PSI-MOD Ontology

Table 1. Metadata
format-version	1.2
date	30:05:2014 00:48
saved-by	John S. Garavelli
auto-generated-by	FormulaOBO.PL
subsetdef	PSI-MOD-slim "subset of protein modifications"
synonymtypedef	DeltaMass-label "Label from MS DeltaMass" EXACT
synonymtypedef	OMSSA-label "Short label from OMSSA" EXACT
synonymtypedef	PSI-MOD-alternate "Alternate name curated by PSI-MOD" EXACT
synonymtypedef	PSI-MOD-label "Short label curated by PSI-MOD" EXACT
synonymtypedef	PSI-MS-label "Agreed label from MS community" RELATED
synonymtypedef	RESID-alternate "Alternate name from RESID" EXACT
synonymtypedef	RESID-misnomer "Misnomer tagged alternate name from RESID" RELATED
synonymtypedef	RESID-name "Name from RESID" EXACT
synonymtypedef	RESID-systematic "Systematic name from RESID" EXACT
synonymtypedef	UniMod-alternate "Alternate name from UniMod" RELATED
synonymtypedef	UniMod-description "Description (full_name) from UniMod" RELATED
synonymtypedef	UniMod-interim "Interim label from UniMod" RELATED
synonymtypedef	UniProt-feature "Protein feature description from UniProtKB" EXACT
default-namespace	PSI-MOD
remark	PSI-MOD version: 1.013.0
remark	RESID release: 75.00
remark	ISO-8601 date: 2014-01-28 14:22Z
remark	Annotation note 1 - "[PSI-MOD:ref]" has been replaced by PubMed:18688235.
remark	Annotation note 2 - When an entry in the RESID Database is annotated with different sources because the same modification can arise from different encoded amino acids, then the PSI-MOD definition for each different source instance carries the RESID cross-reference followed by a hash symbol "#" and a 3 or 4 character label. When an entry in the RESID Database is annotated as a general modification with the same enzymatic activity producing different chemical structures depending on natural variation in the nonproteinaceous substrate, on secondary modifications that do not change the nature of the primary modification, or on a combination of a primary and one or more secondary modifications on the same residue, then the PSI-MOD definition for each different instance carries the RESID cross-reference followed by the special tag "#var".
remark	Annotation note 3 - When an entry in the UniMod database is annotated as a general modification, and one or more instance sites are listed, then the PSI-MOD definition for each different site instance carries the UniMod cross-reference followed by a hash symbol and an amino acid code, "N-term" or "C-term".
remark	Annotation note 4 - The elemental formulas are in strict alphabetical order, not in CAS ("C" and "H" first) order. Isotope numbers are in parentheses before the element symbol, and an element should not occur in a formula both with and without an isotope number. In difference formulas, counts can be zero or negative.
remark	Annotation note 5 - In entries with an isotope indicator in the formula, average masses are meaningless and are assigned the value equal to the monoisotopic mass, but rounded to a lower precision; monoisotopic masses are calculated by using the masses for the indicated isotopes and the most common isotopes for other elements without isotope indicators in the formulas.
remark	Annotation note 6 - For cross-link modifications, the number following "Cross-link" in the comment record indicates the number of amino acid residues that appear in the origin record, used to check the difference formula and masses. This usage differs from RESID, where the cross-link number indicates the maximum number of peptide chains that can be cross-linked.
remark	Annotation note 7 - The synonym cross-reference "MOD:old name" has been replaced by "MOD:alternate name".
remark	Annotation note 8 - The DeltaMass listings for free amino acids have been removed. Most UniMod entries that have not been "approved" have by general agreement not been incorporated unless there has been a request for a specific term by a PRIDE submitter.
remark	Annotation note 9 - The Open Mass Spectrometry Search Algorithm, OMSSA, enumerated list of modifications are being incorporated. The string values are synonyms with the synonymtypedef "OMSSA-label", and their integer values (which are supposed to be stable) are definition cross-references.

Table 2. Term [MOD:00000]
id	MOD:00000
name	protein modification
def	"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModRes" EXACT PSI-MOD-label []

2.1. MOD:00001 alkylated residue

Table 3. Term [MOD:00001]
id	MOD:00001
name	alkylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an alkyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"AlkylRes" EXACT PSI-MOD-label []
xref	Source: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.2. MOD:00002 O-glycosyl-L-serine

Table 4. Term [MOD:00002]
id	MOD:00002
name	O-glycosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-glycosylserine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OGlycoSer" EXACT PSI-MOD-label []
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.3. MOD:00003 UniMod

Table 5. Term [MOD:00003]
id	MOD:00003
name	UniMod
def	"Entry from UniMod." [PubMed:18688235]
comment	This term is for organizational use only and should not be assigned. [JSG]
xref	Source: "none"
is_a	MOD:00032 uncategorized protein modification ! uncategorized protein modification

2.4. MOD:00004 artifact

Table 6. Term [MOD:00004]
id	MOD:00004
name	artifact
def	"Artifact entry from UniMod - OBSOLETE because organizational use is no longer required." [PubMed:18688235]
is_obsolete	true

2.5. MOD:00005 O-glycosyl-L-threonine

Table 7. Term [MOD:00005]
id	MOD:00005
name	O-glycosyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OGlycoThr" EXACT PSI-MOD-label []
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.6. MOD:00006 N-glycosylated residue

Table 8. Term [MOD:00006]
id	MOD:00006
name	N-glycosylated residue
def	"A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NGlycoRes" EXACT PSI-MOD-label []
xref	Source: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.7. MOD:00007 selenium substitution for sulfur

Table 9. Term [MOD:00007]
id	MOD:00007
name	selenium substitution for sulfur
def	"A protein modification that effectively substitutes a selenium atom for a sulfur atom." [PubMed:12148805, UniMod:162]
synonym	"Delta:S(-1)Se(1)" RELATED PSI-MS-label []
synonym	"Se(S)Res" EXACT PSI-MOD-label []
synonym	"Selenium replaces sulphur" RELATED UniMod-description []
xref	DiffAvg: "46.91"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S -1 Se 1"
xref	DiffMono: "47.944450"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00745 selenium containing residue ! selenium containing residue

2.8. MOD:00008 common

Table 10. Term [MOD:00008]
id	MOD:00008
name	common
def	"Entry from UniMod representing one or more entries in RESID. OBSOLETE because organizational use is no longer required." [PubMed:18688235]
is_obsolete	true

2.9. MOD:00009 natural residue

Table 11. Term [MOD:00009]
id	MOD:00009
name	natural residue
def	"A protein modification that removes a residue, or inserts or replaces a residue with a natural, standard or nonstandard, encoded residue." [PubMed:6692818, RESID:AA0000]
subset	PSI-MOD-slim
synonym	"alpha-amino acid" EXACT RESID-name []
synonym	"Res" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "natural"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.10. MOD:00010 L-alanine residue

Table 12. Term [MOD:00010]
id	MOD:00010
name	L-alanine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-alanine." [ChEBI:29948, DeltaMass:0, PubMed:6692818, RESID:AA0001]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"2-aminopropionic acid" EXACT RESID-alternate []
synonym	"2-azanylpropanoic acid" EXACT RESID-alternate []
synonym	"Ala" EXACT PSI-MOD-label []
synonym	"alpha-alanine" EXACT RESID-alternate []
synonym	"alpha-aminopropionic acid" EXACT RESID-alternate []
synonym	"L-alanine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00570 residues isobaric at 71.037114 Da ! residues isobaric at 71.037114 Da
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.11. MOD:00011 L-arginine residue

Table 13. Term [MOD:00011]
id	MOD:00011
name	L-arginine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-arginine." [ChEBI:29952, DeltaMass:0, PubMed:518876, PubMed:6692818, RESID:AA0002]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-(carbamimidamido)pentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-[(aminoiminomethyl)amino]pentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-guanidinopentanoic acid" EXACT RESID-alternate []
synonym	"2-amino-5-guanidinovaleric acid" EXACT RESID-alternate []
synonym	"2-azanyl-5-[bis(azanyl)methylideneazanyl]pentanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-delta-guanidinovaleric acid" EXACT RESID-alternate []
synonym	"Arg" EXACT PSI-MOD-label []
synonym	"L-arginine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 12 N 4 O 1"
xref	MassAvg: "156.19"
xref	MassMono: "156.101111"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.12. MOD:00012 L-asparagine residue

Table 14. Term [MOD:00012]
id	MOD:00012
name	L-asparagine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-asparagine." [ChEBI:29956, DeltaMass:0, PubMed:15736973, PubMed:5681232, PubMed:6692818, PubMed:9789001, RESID:AA0003]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-butanediamic acid" EXACT RESID-systematic []
synonym	"2,4-bis(azanyl)-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"2,4-diamino-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-carbamoylpropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-butanediamic acid" EXACT RESID-alternate []
synonym	"2-aminosuccinamic acid" EXACT RESID-alternate []
synonym	"2-aminosuccinic acid 4-amide" EXACT RESID-alternate []
synonym	"alpha-amino-beta-carbamylpropionic acid" EXACT RESID-alternate []
synonym	"alpha-aminosuccinamic acid" EXACT RESID-alternate []
synonym	"Asn" EXACT PSI-MOD-label []
synonym	"aspartic acid 4-amide" EXACT RESID-alternate []
synonym	"aspartic acid beta-amide" EXACT RESID-alternate []
synonym	"beta-asparagine" EXACT RESID-alternate []
synonym	"L-asparagine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 6 N 2 O 2"
xref	MassAvg: "114.10"
xref	MassMono: "114.042927"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.13. MOD:00013 L-aspartic acid residue

Table 15. Term [MOD:00013]
id	MOD:00013
name	L-aspartic acid residue
def	"A protein modification that effectively converts a source amino acid residue to an L-aspartic acid." [ChEBI:29958, DeltaMass:0, PubMed:1097438, PubMed:339692, PubMed:4399050, PubMed:5764436, PubMed:6692818, PubMed:8089117, PubMed:9521123, PubMed:9582379, RESID:AA0004]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminobutanedioic acid" EXACT RESID-systematic []
synonym	"2-azanylbutanedioic acid" EXACT RESID-alternate []
synonym	"aminosuccinic acid" EXACT RESID-alternate []
synonym	"Asp" EXACT PSI-MOD-label []
synonym	"L-aspartic acid" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.14. MOD:00014 L-cysteine residue

Table 16. Term [MOD:00014]
id	MOD:00014
name	L-cysteine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-cysteine." [ChEBI:29950, DeltaMass:0, PubMed:1310545, PubMed:15790858, PubMed:3447159, PubMed:6692818, PubMed:7338899, RESID:AA0005]
comment	From DeltaMass: Average Mass: 121.
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"®-cysteine" EXACT RESID-alternate []
synonym	"2-amino-3-mercaptopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-mercaptopropionic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"3-mercapto-L-alanine" EXACT RESID-alternate []
synonym	"alpha-amino-beta-mercaptopropanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-mercaptopropionic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-thiolpropionic acid" EXACT RESID-alternate []
synonym	"beta-mercaptoalanine" EXACT RESID-alternate []
synonym	"Cys" EXACT PSI-MOD-label []
synonym	"Cysteine (C, Cys)" EXACT DeltaMass-label []
synonym	"half-cystine" EXACT RESID-alternate []
synonym	"L-(+)-cysteine" EXACT RESID-alternate []
synonym	"L-cysteine" EXACT RESID-name []
synonym	"thioserine" EXACT RESID-alternate []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 1 S 1"
xref	MassAvg: "103.14"
xref	MassMono: "103.009185"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.15. MOD:00015 L-glutamic acid residue

Table 17. Term [MOD:00015]
id	MOD:00015
name	L-glutamic acid residue
def	"A protein modification that effectively converts a source amino acid residue to an L-glutamic acid." [ChEBI:29972, DeltaMass:0, PubMed:1881881, PubMed:4565668, PubMed:4922541, PubMed:6692818, PubMed:9326660, PubMed:957425, RESID:AA0006]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminopentanedioic acid" EXACT RESID-systematic []
synonym	"1-aminopropane-1,3-dicarboxylic acid" EXACT RESID-alternate []
synonym	"2-aminoglutaric acid" EXACT RESID-alternate []
synonym	"2-azanylpentanedioic acid" EXACT RESID-alternate []
synonym	"alpha-aminoglutaric acid" EXACT RESID-alternate []
synonym	"Glu" EXACT PSI-MOD-label []
synonym	"glutaminic acid" EXACT RESID-alternate []
synonym	"L-glutamic acid" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.16. MOD:00016 L-glutamine residue

Table 18. Term [MOD:00016]
id	MOD:00016
name	L-glutamine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-glutamine." [ChEBI:30011, DeltaMass:0, PubMed:3340166, PubMed:6692818, PubMed:9342308, RESID:AA0007]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-pentanediamic acid" EXACT RESID-systematic []
synonym	"2,5-bis(azanyl)-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"2,5-diamino-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-carbamoylbutanoic acid" EXACT RESID-alternate []
synonym	"2-aminoglutaramic acid" EXACT RESID-alternate []
synonym	"alpha-amino-gamma-carbamylbutyric acid" EXACT RESID-alternate []
synonym	"Gln" EXACT PSI-MOD-label []
synonym	"glutamic acid 5-amide" EXACT RESID-alternate []
synonym	"glutamic acid gamma-amide" EXACT RESID-alternate []
synonym	"glutamide" EXACT RESID-alternate []
synonym	"L-glutamine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 8 N 2 O 2"
xref	MassAvg: "128.13"
xref	MassMono: "128.058578"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00894 residues isobaric at 128.058578 Da ! residues isobaric at 128.058578 Da
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.17. MOD:00017 glycine residue

Table 19. Term [MOD:00017]
id	MOD:00017
name	glycine residue
def	"A protein modification that effectively converts a source amino acid residue to a glycine." [ChEBI:29947, DeltaMass:0, PubMed:1310545, PubMed:6692818, RESID:AA0008]
subset	PSI-MOD-slim
synonym	"aminoacetic acid" EXACT RESID-alternate []
synonym	"aminoethanoic acid" EXACT RESID-systematic []
synonym	"azanylethanoic acid" EXACT RESID-alternate []
synonym	"Gly" EXACT PSI-MOD-label []
synonym	"glycine" EXACT RESID-name []
synonym	"glycocoll" EXACT RESID-alternate []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 2 H 3 N 1 O 1"
xref	MassAvg: "57.05"
xref	MassMono: "57.021464"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.18. MOD:00018 L-histidine residue

Table 20. Term [MOD:00018]
id	MOD:00018
name	L-histidine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-histidine." [ChEBI:29979, DeltaMass:0, PubMed:14342316, PubMed:2722967, PubMed:512, PubMed:5460889, PubMed:6129252, PubMed:6692818, PubMed:6876174, RESID:AA0009]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-azanyl-3-(1H-imidazol-4-yl)propanoic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-(1H-imidazol-5-yl)propanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"4-(2-amino-2-carboxyethyl)imidazole" EXACT RESID-alternate []
synonym	"alpha-amino-beta-(4-imidazole)propionic acid" EXACT RESID-alternate []
synonym	"glyoxaline-5-alanine" EXACT RESID-alternate []
synonym	"His" EXACT PSI-MOD-label []
synonym	"L-histidine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 7 N 3 O 1"
xref	MassAvg: "137.14"
xref	MassMono: "137.058912"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.19. MOD:00019 L-isoleucine residue

Table 21. Term [MOD:00019]
id	MOD:00019
name	L-isoleucine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-isoleucine." [ChEBI:30009, DeltaMass:0, PubMed:6692818, RESID:AA0010]
subset	PSI-MOD-slim
synonym	"(2S,3S)-2-amino-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-methylpentanoic acid" EXACT RESID-alternate []
synonym	"3-methyl-norvaline" EXACT RESID-alternate []
synonym	"alpha-amino-beta-methylvaleric acid" EXACT RESID-alternate []
synonym	"Ile" EXACT PSI-MOD-label []
synonym	"Isoleucyl" EXACT DeltaMass-label []
synonym	"L-erythro-isoleucine" EXACT RESID-alternate []
synonym	"L-isoleucine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00306 residues isobaric at 113.084064 Da ! residues isobaric at 113.084064 Da
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.20. MOD:00020 L-leucine residue

Table 22. Term [MOD:00020]
id	MOD:00020
name	L-leucine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-leucine." [ChEBI:30006, DeltaMass:0, PubMed:11478885, PubMed:6692818, RESID:AA0011]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-4-methylpentanoic acid" EXACT RESID-alternate []
synonym	"4-methyl-norvaline" EXACT RESID-alternate []
synonym	"alpha-amino-gamma-methylvaleric acid" EXACT RESID-alternate []
synonym	"alpha-aminoisocaproic acid" EXACT RESID-alternate []
synonym	"L-leucine" EXACT RESID-name []
synonym	"Leu" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00306 residues isobaric at 113.084064 Da ! residues isobaric at 113.084064 Da
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.21. MOD:00021 L-lysine residue

Table 23. Term [MOD:00021]
id	MOD:00021
name	L-lysine residue
def	"A protein modification that effectively converts a source amino acid residue to L-lysine." [ChEBI:29967, DeltaMass:0, PubMed:3106962, PubMed:6120171, PubMed:6692818, RESID:AA0012]
subset	PSI-MOD-slim
synonym	"(2S)-2,6-diaminohexanoic acid" EXACT RESID-systematic []
synonym	"2,6-bis(azanyl)hexanoic acid" EXACT RESID-alternate []
synonym	"6-amino-L-norleucine" EXACT RESID-alternate []
synonym	"ACT_SITE Schiff-base intermediate with substrate" EXACT UniProt-feature []
synonym	"alpha,epsilon-diaminocaproic acid" EXACT RESID-alternate []
synonym	"L-lysine" EXACT RESID-name []
synonym	"Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 12 N 2 O 1"
xref	MassAvg: "128.18"
xref	MassMono: "128.094963"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00893 residues isobaric at 128.0-128.1 ! residues isobaric at 128.0-128.1
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.22. MOD:00022 L-methionine residue

Table 24. Term [MOD:00022]
id	MOD:00022
name	L-methionine residue
def	"A protein modification that effectively converts a source amino acid residue to L-methionine." [ChEBI:29983, DeltaMass:0, PubMed:6411710, PubMed:6692818, RESID:AA0013]
comment	From DeltaMass: Average Mass: 149
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-amino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-(methylthio)butyric acid" EXACT RESID-alternate []
synonym	"2-azanyl-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-gamma-methylmercaptobutyric acid" EXACT RESID-alternate []
synonym	"alpha-amino-gamma-methylthiobutyric acid" EXACT RESID-alternate []
synonym	"gamma-methylthio-alpha-aminobutyric acid" EXACT RESID-alternate []
synonym	"L-(-)-methionine" EXACT RESID-alternate []
synonym	"L-methionine" EXACT RESID-name []
synonym	"Met" EXACT PSI-MOD-label []
synonym	"S-methyl-L-homocysteine" EXACT RESID-alternate []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.040485"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.23. MOD:00023 L-phenylalanine residue

Table 25. Term [MOD:00023]
id	MOD:00023
name	L-phenylalanine residue
def	"A protein modification that effectively converts a source amino acid residue to L-phenylalanine." [ChEBI:29997, DeltaMass:0, PubMed:6692818, RESID:AA0014]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-phenylpropanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-phenylpropionic acid" EXACT RESID-alternate []
synonym	"L-phenylalanine" EXACT RESID-name []
synonym	"Phe" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 9 H 9 N 1 O 1"
xref	MassAvg: "147.18"
xref	MassMono: "147.068414"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.24. MOD:00024 L-proline residue

Table 26. Term [MOD:00024]
id	MOD:00024
name	L-proline residue
def	"A protein modification that effectively converts a source amino acid residue to L-proline." [ChEBI:30017, DeltaMass:0, PubMed:6692818, PubMed:8547259, RESID:AA0015]
subset	PSI-MOD-slim
synonym	"(2S)-2-pyrrolidinecarboxylic acid" EXACT RESID-systematic []
synonym	"L-proline" EXACT RESID-name []
synonym	"Pro" EXACT PSI-MOD-label []
synonym	"pyrrolidine-2-carboxylic acid" EXACT RESID-alternate []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 7 N 1 O 1"
xref	MassAvg: "97.12"
xref	MassMono: "97.052764"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.25. MOD:00025 L-serine residue

Table 27. Term [MOD:00025]
id	MOD:00025
name	L-serine residue
def	"A protein modification that effectively converts a source amino acid residue to L-serine." [ChEBI:29999, DeltaMass:0, PubMed:4399050, PubMed:6692818, RESID:AA0016]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-hydroxypropanoic acid" EXACT RESID-alternate []
synonym	"3-hydroxy-L-alanine" EXACT RESID-alternate []
synonym	"alpha-amino-beta-hydroxypropionic acid" EXACT RESID-alternate []
synonym	"beta-hydroxyalanine" EXACT RESID-alternate []
synonym	"L-serine" EXACT RESID-name []
synonym	"Ser" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 2"
xref	MassAvg: "87.08"
xref	MassMono: "87.032028"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.26. MOD:00026 L-threonine residue

Table 28. Term [MOD:00026]
id	MOD:00026
name	L-threonine residue
def	"A protein modification that effectively converts a source amino acid residue to L-threonine." [ChEBI:30013, DeltaMass:0, PubMed:2989287, PubMed:6692818, RESID:AA0017]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-hydroxybutanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-hydroxybutyric acid" EXACT RESID-alternate []
synonym	"beta-methylserine" EXACT RESID-alternate []
synonym	"L-threo-threonine" EXACT RESID-alternate []
synonym	"L-threonine" EXACT RESID-name []
synonym	"Thr" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 7 N 1 O 2"
xref	MassAvg: "101.10"
xref	MassMono: "101.047678"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.27. MOD:00027 L-tryptophan residue

Table 29. Term [MOD:00027]
id	MOD:00027
name	L-tryptophan residue
def	"A protein modification that effectively converts a source amino acid residue to L-tryptophan." [ChEBI:29954, DeltaMass:0, PubMed:2059637, PubMed:6692818, PubMed:9324768, RESID:AA0018]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-(1H-indol-3-yl)propanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-(3-indolyl)propionoic acid" EXACT RESID-alternate []
synonym	"beta(3-indolyl)alanine" EXACT RESID-alternate []
synonym	"L-tryptophan" EXACT RESID-name []
synonym	"Trp" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 11 H 10 N 2 O 1"
xref	MassAvg: "186.21"
xref	MassMono: "186.079313"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.28. MOD:00028 L-tyrosine residue

Table 30. Term [MOD:00028]
id	MOD:00028
name	L-tyrosine residue
def	"A protein modification that effectively converts a source amino acid residue to L-tyrosine." [ChEBI:29975, DeltaMass:0, PubMed:2190093, PubMed:2542938, PubMed:5550972, PubMed:6061414, PubMed:6120171, PubMed:6692818, RESID:AA0019]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-(para-hydroxyphenyl)propionic acid" EXACT RESID-alternate []
synonym	"L-tyrosine" EXACT RESID-name []
synonym	"p-tyrosine" EXACT RESID-alternate []
synonym	"para-hydroxyphenylalanine" EXACT RESID-alternate []
synonym	"Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 9 H 9 N 1 O 2"
xref	MassAvg: "163.18"
xref	MassMono: "163.063329"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.29. MOD:00029 L-valine residue

Table 31. Term [MOD:00029]
id	MOD:00029
name	L-valine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-valine." [ChEBI:30015, DeltaMass:0, PubMed:6692818, RESID:AA0020]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-methylbutanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-methylbutyric acid" EXACT RESID-alternate []
synonym	"alpha-aminoisovaleric acid" EXACT RESID-alternate []
synonym	"L-valine" EXACT RESID-name []
synonym	"Val" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 9 N 1 O 1"
xref	MassAvg: "99.13"
xref	MassMono: "99.068414"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01441 natural, standard, encoded residue ! natural, standard, encoded residue

2.30. MOD:00030 N-formyl-L-methionine residue

Table 32. Term [MOD:00030]
id	MOD:00030
name	N-formyl-L-methionine residue
def	"A protein modification that effectively converts a source amino acid residue to an N-formyl-L-methionine, a natural pretranslational modification." [ChEBI:33718, OMSSA:22, PubMed:10825024, PubMed:11152118, PubMed:2165784, PubMed:3042771, PubMed:8758896, RESID:AA0021#FMET, UniMod:107#N-term]
subset	PSI-MOD-slim
synonym	"(2S)-2-formylamino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-formamido-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"2-formylamino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"2-formylazanyl-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"Addition of N-formyl met" RELATED UniMod-description []
synonym	"fMet" EXACT PSI-MOD-label []
synonym	"FormylMet" RELATED PSI-MS-label []
synonym	"MOD_RES N-formylmethionine" EXACT UniProt-feature []
synonym	"N-formyl-L-methionine" EXACT RESID-name []
synonym	"N-formylated L-methionine" EXACT PSI-MOD-alternate []
synonym	"nformylmet" EXACT OMSSA-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 10 N 1 O 2 S 1"
xref	MassAvg: "160.21"
xref	MassMono: "160.043225"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00868 natural, non-standard encoded residue ! natural, non-standard encoded residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.31. MOD:00031 L-selenocysteine residue

Table 33. Term [MOD:00031]
id	MOD:00031
name	L-selenocysteine residue
def	"A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification." [ChEBI:30000, PubMed:10523135, PubMed:1066676, PubMed:2037562, PubMed:2963330, PubMed:4734725, PubMed:6076213, PubMed:6217842, PubMed:6714945, RESID:AA0022]
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-selanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-selanylpropanoic acid" EXACT RESID-alternate []
synonym	"3-selenylalanine" EXACT RESID-alternate []
synonym	"L-selenocysteine" EXACT RESID-name []
synonym	"NON_STD Selenocysteine" EXACT UniProt-feature []
synonym	"Sec" EXACT PSI-MOD-label []
synonym	"SeCys" EXACT RESID-alternate []
synonym	"selenium cysteine" EXACT RESID-alternate []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0 Se 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 1 Se 1"
xref	MassAvg: "150.05"
xref	MassMono: "150.953635"
xref	Origin: "U"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00745 selenium containing residue ! selenium containing residue
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00868 natural, non-standard encoded residue ! natural, non-standard encoded residue

2.32. MOD:00032 uncategorized protein modification

Table 34. Term [MOD:00032]
id	MOD:00032
name	uncategorized protein modification
def	"A protein modification that is not chemically categorized." [PubMed:18688235]
comment	This term is for organizational use only and should not be assigned. [JSG]
xref	Source: "none"
is_a	[MOD:00000] ! protein modification

2.33. MOD:00033 crosslinked residues

Table 35. Term [MOD:00033]
id	MOD:00033
name	crosslinked residues
def	"A protein modification that crosslinks two or more amino acid residues with covalent bonds." [PubMed:18688235]
comment	The covalent bond is formed directly between sidechain atoms. If non-aminoacid atoms are involved in connecting two or more peptide chain residues peptide chain, the connection is classified as a multivalent binding site.
subset	PSI-MOD-slim
synonym	"XLNK-Res-Res" EXACT PSI-MOD-label []
xref	Source: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.34. MOD:00034 L-cystine (cross-link)

Table 36. Term [MOD:00034]
id	MOD:00034
name	L-cystine (cross-link)
def	"A protein modification that effectively cross-links two L-cysteine residues to form L-cystine." [ChEBI:16283, DeltaMass:0, PubMed:1988019, PubMed:2001356, PubMed:2076469, PubMed:3083866, PubMed:366603, PubMed:7918467, PubMed:8344916, RESID:AA0025#CYS2]
comment	Cross-link 2; for formation of a disulfide bond between a peptide cysteine and a free cysteine, see MOD:00765.
subset	PSI-MOD-slim
synonym	"(2R,2’R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid" RELATED RESID-misnomer []
synonym	"3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobisalanine" EXACT RESID-alternate []
synonym	"3,3'-dithiodialanine" EXACT RESID-alternate []
synonym	"beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide" EXACT RESID-alternate []
synonym	"beta,beta'-dithiodialanine" EXACT RESID-alternate []
synonym	"bis(alpha-aminopropionic acid)-beta-disulfide" EXACT RESID-alternate []
synonym	"bis(beta-amino-beta-carboxyethyl)disulfide" EXACT RESID-alternate []
synonym	"Cys2" EXACT PSI-MOD-label []
synonym	"Cystine ((Cys)2)" EXACT DeltaMass-label []
synonym	"dicysteine" EXACT RESID-alternate []
synonym	"DISULFID" EXACT UniProt-feature []
synonym	"DISULFID Interchain" EXACT UniProt-feature []
synonym	"L-cystine" EXACT RESID-name []
synonym	"XLNK-SCys-SCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 2 S 2"
xref	MassAvg: "204.26"
xref	MassMono: "204.002720"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00689 disulfide crosslinked residues ! disulfide crosslinked residues

2.35. MOD:00035 (2S,3R)-3-hydroxyasparagine

Table 37. Term [MOD:00035]
id	MOD:00035
name	(2S,3R)-3-hydroxyasparagine
def	"A protein modification that effectively converts an L-asparagine residue to (2S,3R)-3-hydroxyasparagine." [PubMed:11823643, PubMed:2820791, RESID:AA0026]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"(2S,3R)-2-amino-3-hydroxy-4-butanediamic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-3-hydroxyasparagine" EXACT RESID-name []
synonym	"(3R)3HyAsn" EXACT PSI-MOD-label []
synonym	"2-azanyl-3-hydroxy-4-butanediamic acid" EXACT RESID-alternate []
synonym	"erythro-beta-hydroxylated L-asparagine" EXACT PSI-MOD-alternate []
synonym	"L-erythro-beta-hydroxyasparagine" EXACT RESID-alternate []
synonym	"MOD_RES (3R)-3-hydroxyasparagine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 6 N 2 O 3"
xref	MassAvg: "130.10"
xref	MassMono: "130.037842"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01688 3-hydroxy-L-asparagine ! 3-hydroxy-L-asparagine

2.36. MOD:00036 (2S,3R)-3-hydroxyaspartic acid

Table 38. Term [MOD:00036]
id	MOD:00036
name	(2S,3R)-3-hydroxyaspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid." [OMSSA:59, PubMed:6572939, PubMed:6871167, PubMed:8355279, RESID:AA0027, UniMod:35#D]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-hydroxybutanedioic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-3-hydroxyaspartic acid" EXACT RESID-name []
synonym	"(3R)3HyAsp" EXACT PSI-MOD-label []
synonym	"2-amino-3-hydroxysuccinic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-hydroxybutanedioic acid" EXACT RESID-alternate []
synonym	"3-hydroxyaspartic acid" EXACT RESID-alternate []
synonym	"erythro-beta-hydroxylated L-aspartic acid" EXACT PSI-MOD-alternate []
synonym	"hydroxylationd" EXACT OMSSA-label []
synonym	"L-erythro-beta-hydroxyaspartic acid" EXACT RESID-alternate []
synonym	"MOD_RES (3R)-3-hydroxyaspartate" EXACT UniProt-feature []
synonym	"Oxidation" RELATED PSI-MS-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 5 N 1 O 4"
xref	MassAvg: "131.09"
xref	MassMono: "131.021858"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01926 3-hydroxy-L-aspartic acid ! 3-hydroxy-L-aspartic acid

2.37. MOD:00037 5-hydroxy-L-lysine

Table 39. Term [MOD:00037]
id	MOD:00037
name	5-hydroxy-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to one of the diastereomeric 5-hydroxy-L-lysine residues." [ChEBI:60175, PubMed:18688235]
subset	PSI-MOD-slim
synonym	"5-hydroxylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"5HyLys" EXACT PSI-MOD-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 2 O 2"
xref	MassAvg: "144.17"
xref	MassMono: "144.089878"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01047 monohydroxylated lysine ! monohydroxylated lysine

2.38. MOD:00038 3-hydroxy-L-proline

Table 40. Term [MOD:00038]
id	MOD:00038
name	3-hydroxy-L-proline
def	"A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline." [ChEBI:16889, PubMed:2400108, PubMed:3734192, PubMed:4343807, RESID:AA0029]
subset	PSI-MOD-slim
synonym	"(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"3-hydroxy-L-proline" EXACT RESID-name []
synonym	"3-hydroxylated L-proline" EXACT PSI-MOD-alternate []
synonym	"3-trans-hydroxy-L-proline" EXACT RESID-alternate []
synonym	"3HyPro" EXACT PSI-MOD-label []
synonym	"beta-hydroxypyrrolidine-alpha-carboxylic acid" EXACT RESID-alternate []
synonym	"L-threo-3-hydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES 3-hydroxyproline" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01024 monohydroxylated proline ! monohydroxylated proline

2.39. MOD:00039 4-hydroxy-L-proline

Table 41. Term [MOD:00039]
id	MOD:00039
name	4-hydroxy-L-proline
def	"A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline" [ChEBI:18095, PubMed:11292863, PubMed:2400108, PubMed:3734192, RESID:AA0030]
subset	PSI-MOD-slim
synonym	"(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"4-hydroxy-L-proline" EXACT RESID-name []
synonym	"4-hydroxylated L-proline" EXACT PSI-MOD-alternate []
synonym	"4-hydroxyproline" EXACT RESID-alternate []
synonym	"4-trans-hydroxy-L-proline" EXACT RESID-alternate []
synonym	"4HyPro" EXACT PSI-MOD-label []
synonym	"gamma-hydroxypyrrolidine-alpha-carboxylic acid" EXACT RESID-alternate []
synonym	"L-threo-4-hydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES 4-hydroxyproline" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01024 monohydroxylated proline ! monohydroxylated proline

2.40. MOD:00040 2-pyrrolidone-5-carboxylic acid (Gln)

Table 42. Term [MOD:00040]
id	MOD:00040
name	2-pyrrolidone-5-carboxylic acid (Gln)
def	"A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid." [ChEBI:30652, DeltaMass:123, OMSSA:110, PubMed:10214721, PubMed:1836357, PubMed:26343, PubMed:3473473, RESID:AA0031#GLN, UniMod:28#Q]
comment	DeltaMass gives a formula C 5 H 5 N 1 O 2 with mass 111.1
subset	PSI-MOD-slim
synonym	"(2S)-5-oxo-2-pyrrolidinecarboxylic acid" EXACT RESID-systematic []
synonym	"2-oxopyrrolidine-5-carboxylic acid" EXACT RESID-alternate []
synonym	"2-pyrrolidone-5-carboxylic acid" EXACT RESID-name []
synonym	"5-oxoproline" EXACT RESID-alternate []
synonym	"5-oxopyrrolidine-2-carboxylic acid" EXACT RESID-alternate []
synonym	"5-pyrrolidone-2-carboxylic acid" EXACT RESID-alternate []
synonym	"Gln→pyro-Glu" RELATED PSI-MS-label []
synonym	"MOD_RES Pyrrolidone carboxylic acid" EXACT UniProt-feature []
synonym	"N-pyrrolidone carboxyl (N terminus)" EXACT DeltaMass-label []
synonym	"ntermpeppyroq" EXACT OMSSA-label []
synonym	"PCA" EXACT RESID-alternate []
synonym	"PyrGlu(Gln)" EXACT PSI-MOD-label []
synonym	"Pyro-glu from Q" RELATED UniMod-description []
synonym	"pyroglutamic acid" EXACT RESID-alternate []
synonym	"Pyroglutamic Acid formed from Gln" EXACT DeltaMass-label []
synonym	"Pyroglutamyl" EXACT DeltaMass-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 5 H 6 N 1 O 2"
xref	MassAvg: "112.11"
xref	MassMono: "112.039853"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:01048 2-pyrrolidone-5-carboxylic acid ! 2-pyrrolidone-5-carboxylic acid
is_a	MOD:01160 deaminated residue ! deaminated residue

2.41. MOD:00041 L-gamma-carboxyglutamic acid

Table 43. Term [MOD:00041]
id	MOD:00041
name	L-gamma-carboxyglutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid." [DeltaMass:217, OMSSA:48, PubMed:10517147, PubMed:1807167, PubMed:3263814, PubMed:4528109, PubMed:7457858, PubMed:8135347, PubMed:8868490, PubMed:9188685, RESID:AA0032, UniMod:299#E]
comment	DeltaMass has an incorrect formula C 6 H 7 N 5 O 1 (N and O reversed) with mass 173.
subset	PSI-MOD-slim
synonym	"(3S)-3-aminopropane-1,1,3-tricarboxylic acid" EXACT RESID-systematic []
synonym	"(3S)-3-azanylpropane-1,1,3-tricarboxylic acid" EXACT RESID-alternate []
synonym	"1-carboxyglutamic acid" RELATED RESID-misnomer []
synonym	"3-amino-1,1,3-propanetricarboxylic acid" EXACT RESID-alternate []
synonym	"3-azanylpropane-1,1,3-tricarboxylic acid" EXACT RESID-alternate []
synonym	"4-carboxyglutamic acid" EXACT RESID-alternate []
synonym	"4CbxGlu" EXACT PSI-MOD-label []
synonym	"Carboxy" RELATED PSI-MS-label []
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxy Glutamyl" EXACT DeltaMass-label []
synonym	"Carboxylation" RELATED UniMod-description []
synonym	"gamma-carboxylated L-glutamic acid" EXACT PSI-MOD-alternate []
synonym	"gammacarboxyle" EXACT OMSSA-label []
synonym	"L-gamma-carboxyglutamic acid" EXACT RESID-name []
synonym	"MOD_RES 4-carboxyglutamate" EXACT UniProt-feature []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 6 H 7 N 1 O 5"
xref	MassAvg: "173.12"
xref	MassMono: "173.032422"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.42. MOD:00042 L-aspartic 4-phosphoric anhydride

Table 44. Term [MOD:00042]
id	MOD:00042
name	L-aspartic 4-phosphoric anhydride
def	"A protein modification that effectively converts an L-aspartic acid residue to L-aspartic 4-phosphoric anhydride." [ChEBI:15836, PubMed:4357737, RESID:AA0033, UniMod:21#D]
synonym	"(2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acid" EXACT RESID-systematic []
synonym	"2-aminobutanedioic 4-phosphoric anhydride" EXACT RESID-alternate []
synonym	"2-azanyl-4-oxo-4-(phosphonooxy)butanoic acid" EXACT RESID-alternate []
synonym	"4-oxo-O-phosphono-L-homoserine" EXACT RESID-alternate []
synonym	"4-phosphoaspartic acid" EXACT RESID-alternate []
synonym	"4-phosphorylated L-aspartatic acid" EXACT PSI-MOD-alternate []
synonym	"ACT_SITE 4-aspartylphosphate intermediate" EXACT UniProt-feature []
synonym	"beta-aspartyl phosphate" EXACT RESID-alternate []
synonym	"L-aspartic 4-phosphoric anhydride" EXACT RESID-name []
synonym	"MOD_RES 4-aspartylphosphate" EXACT UniProt-feature []
synonym	"PAsp" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phosphorylation" RELATED UniMod-description []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 4 H 6 N 1 O 6 P 1"
xref	MassAvg: "195.07"
xref	MassMono: "194.993274"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01455 O-phosphorylated residue ! O-phosphorylated residue

2.43. MOD:00043 S-phospho-L-cysteine

Table 45. Term [MOD:00043]
id	MOD:00043
name	S-phospho-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine." [PubMed:3142516, PubMed:7961745, PubMed:8128219, RESID:AA0034, UniMod:21#C]
synonym	"(2R)-2-amino-3-(phosphonosulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-(phosphonosulfanyl)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE Phosphocysteine intermediate" EXACT UniProt-feature []
synonym	"cysteine phosphate thioester" EXACT RESID-alternate []
synonym	"MOD_RES Phosphocysteine" EXACT UniProt-feature []
synonym	"PCys" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"S-phospho-L-cysteine" EXACT RESID-name []
synonym	"S-phosphonocysteine" EXACT RESID-alternate []
synonym	"S-phosphorylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S3-phosphocysteine" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1 S 0"
xref	DiffMono: "79.966331"
xref	Formula: "C 3 H 6 N 1 O 4 P 1 S 1"
xref	MassAvg: "183.12"
xref	MassMono: "182.975515"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00696 phosphorylated residue ! phosphorylated residue
is_a	MOD:00777 residues isobaric at 182.96-182.98 Da ! residues isobaric at 182.96-182.98 Da
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.44. MOD:00044 1'-phospho-L-histidine

Table 46. Term [MOD:00044]
id	MOD:00044
name	1'-phospho-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to tele-phospho-L-histidine (N-tau-phospho-L-histidine, 1'-phospho-L-histidine)." [PubMed:11038361, PubMed:5642389, PubMed:6692818, RESID:AA0035]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-phospho-L-histidine" EXACT RESID-name []
synonym	"2-azanyl-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE Tele-phosphohistidine intermediate" EXACT UniProt-feature []
synonym	"histidine-3-phosphate" RELATED RESID-misnomer []
synonym	"histidine-N(epsilon)-phosphate" EXACT RESID-alternate []
synonym	"histidine-N1'-phosphate" EXACT RESID-alternate []
synonym	"MOD_RES Tele-phosphohistidine" EXACT UniProt-feature []
synonym	"N(tau)-phosphohistidine" EXACT RESID-alternate []
synonym	"N1-phosphonohistidine" EXACT RESID-alternate []
synonym	"NE2-phosphonohistidine" EXACT RESID-alternate []
synonym	"Ntau-phosphorylated L-histidine" EXACT PSI-MOD-alternate []
synonym	"NtPHis" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"tele-phosphohistidine" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 6 H 8 N 3 O 4 P 1"
xref	MassAvg: "217.12"
xref	MassMono: "217.025242"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00890 phosphorylated L-histidine ! phosphorylated L-histidine

2.45. MOD:00045 3'-phospho-L-histidine

Table 47. Term [MOD:00045]
id	MOD:00045
name	3'-phospho-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine)." [PubMed:1549615, PubMed:5642389, PubMed:6692818, PubMed:7669763, PubMed:7803390, RESID:AA0036]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid" EXACT RESID-alternate []
synonym	"3'-phospho-L-histidine" EXACT RESID-name []
synonym	"ACT_SITE Pros-phosphohistidine intermediate" EXACT UniProt-feature []
synonym	"histidine-1-phosphate" RELATED RESID-misnomer []
synonym	"histidine-N(delta)-phosphate" EXACT RESID-alternate []
synonym	"histidine-N3'-phosphate" EXACT RESID-alternate []
synonym	"MOD_RES Pros-phosphohistidine" EXACT UniProt-feature []
synonym	"N(pi)-phosphohistidine" EXACT RESID-alternate []
synonym	"N3-phosphonohistidine" EXACT RESID-alternate []
synonym	"ND1-phosphonohistidine" EXACT RESID-alternate []
synonym	"Npi-phosphorylated L-histidine" EXACT PSI-MOD-alternate []
synonym	"NpPHis" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"pros-phosphohistidine" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 6 H 8 N 3 O 4 P 1"
xref	MassAvg: "217.12"
xref	MassMono: "217.025242"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00890 phosphorylated L-histidine ! phosphorylated L-histidine

2.46. MOD:00046 O-phospho-L-serine

Table 48. Term [MOD:00046]
id	MOD:00046
name	O-phospho-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-phospho-L-serine." [ChEBI:15811, DeltaMass:0, OMSSA:6, PubMed:12923550, PubMed:4065410, PubMed:8061611, RESID:AA0037, UniMod:21#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(phosphonooxy)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-hydroxypropanoic acid 3-phosphate" EXACT RESID-alternate []
synonym	"2-azanyl-3-(phosphonooxy)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE Phosphoserine intermediate" EXACT UniProt-feature []
synonym	"MOD_RES Phosphoserine" EXACT UniProt-feature []
synonym	"O-phospho-L-serine" EXACT RESID-name []
synonym	"O-phosphonoserine" EXACT RESID-alternate []
synonym	"O-phosphorylated L-serine" EXACT PSI-MOD-alternate []
synonym	"O3-phosphoserine" EXACT RESID-alternate []
synonym	"OPSer" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phospho Seryl" EXACT DeltaMass-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"phosphorylations" EXACT OMSSA-label []
synonym	"serine phosphate ester" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 3 H 6 N 1 O 5 P 1"
xref	MassAvg: "167.06"
xref	MassMono: "166.998359"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00771 residues isobaric at 166.98-167.00 Da ! residues isobaric at 166.98-167.00 Da
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01455 O-phosphorylated residue ! O-phosphorylated residue

2.47. MOD:00047 O-phospho-L-threonine

Table 49. Term [MOD:00047]
id	MOD:00047
name	O-phospho-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine." [ChEBI:21967, DeltaMass:0, OMSSA:7, PubMed:12923550, PubMed:7678926, RESID:AA0038, UniMod:21#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(phosphonooxy)butanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-hydroxybutanoic acid 3-phosphate" EXACT RESID-alternate []
synonym	"2-azanyl-3-(phosphonooxy)butanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES Phosphothreonine" EXACT UniProt-feature []
synonym	"O-phospho-L-threonine" EXACT RESID-name []
synonym	"O-phosphorylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"O3-phosphothreonine" EXACT RESID-alternate []
synonym	"OPThr" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phospho Threonyl" EXACT DeltaMass-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"phosphorylationt" EXACT OMSSA-label []
synonym	"threonine phosphate ester" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 4 H 8 N 1 O 5 P 1"
xref	MassAvg: "181.08"
xref	MassMono: "181.014009"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00773 residues isobaric at 181.00-181.02 Da ! residues isobaric at 181.00-181.02 Da
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01455 O-phosphorylated residue ! O-phosphorylated residue

2.48. MOD:00048 O4'-phospho-L-tyrosine

Table 50. Term [MOD:00048]
id	MOD:00048
name	O4'-phospho-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine." [DeltaMass:0, OMSSA:8, PubMed:10226369, PubMed:1725475, RESID:AA0039, UniMod:21#Y]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate" EXACT RESID-alternate []
synonym	"2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES Phosphotyrosine" EXACT UniProt-feature []
synonym	"O4'-phospho-L-tyrosine" EXACT RESID-name []
synonym	"O4'-phosphorylated L-tyrosine" EXACT PSI-MOD-alternate []
synonym	"O4-phosphotyrosine" EXACT RESID-alternate []
synonym	"OPTyr" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phospho Tyrosinyl" EXACT DeltaMass-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"phosphorylationy" EXACT OMSSA-label []
synonym	"tyrosine phosphate" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 9 H 10 N 1 O 5 P 1"
xref	MassAvg: "243.15"
xref	MassMono: "243.029659"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00774 residues isobaric at 243.02-243.03 Da ! residues isobaric at 243.02-243.03 Da
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01455 O-phosphorylated residue ! O-phosphorylated residue

2.49. MOD:00049 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine

Table 51. Term [MOD:00049]
id	MOD:00049
name	2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to diphthamide." [ChEBI:16692, DeltaMass:122, PubMed:15316019, PubMed:7430147, RESID:AA0040, UniMod:375#H]
synonym	"(2R)-1-amino-4-(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-aminium" EXACT RESID-systematic []
synonym	"(3-[4-(2-amino-2-carboxy-ethyl)-1H-imidazol-2-yl]-1-carbamoyl-propyl)-trimethylammonium" EXACT RESID-alternate []
synonym	"1-azanyl-4-(4-[2-azanyl-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-azanium" EXACT RESID-alternate []
synonym	"2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine" EXACT RESID-name []
synonym	"2-[®-3-carboxamido-3-(trimethylammonio)propyl]-4-((S)-2-amino-2-carboxyethyl)-1H-imidazole" EXACT RESID-alternate []
synonym	"2-[3-carboxamido-3-(trimethylammonio)propyl]histidine" EXACT RESID-alternate []
synonym	"2-amino-3-[[2-(3-amino-3-carbamoyl-prop-1-enyl)-1,1,3-trimethyl-2,3-dihydroimidazol-5-yl]]propanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-[[5-(2-amino-2-carboxylato-ethyl)-1,1,3-trimethyl-2,3-dihydroimidazol-2-yl]]but-3-enamide" EXACT RESID-alternate []
synonym	"alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1H-imidazole-2-propanaminium" EXACT RESID-alternate []
synonym	"Diphth" EXACT PSI-MOD-label []
synonym	"Diphthamide" RELATED PSI-MS-label []
synonym	"Diphthamide" RELATED UniMod-description []
synonym	"diphthamide" EXACT RESID-alternate []
synonym	"diphthamide (from histidine)" EXACT DeltaMass-label []
synonym	"MOD_RES Diphthamide" EXACT UniProt-feature []
xref	DiffAvg: "143.21"
xref	DiffFormula: "C 7 H 15 N 2 O 1"
xref	DiffMono: "143.117890"
xref	FormalCharge: "1+"
xref	Formula: "C 13 H 22 N 5 O 2"
xref	MassAvg: "280.35"
xref	MassMono: "280.176801"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.50. MOD:00050 N-acetyl-L-alanine

Table 52. Term [MOD:00050]
id	MOD:00050
name	N-acetyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N-acetyl-L-alanine." [PubMed:363452, PubMed:4700463, RESID:AA0041]
subset	PSI-MOD-slim
synonym	"(2S)-2-(acetamido)propanoic acid" EXACT RESID-systematic []
synonym	"2-(acetylamino)propanoic acid" EXACT RESID-alternate []
synonym	"2-(acetylazanyl)propanoic acid" EXACT RESID-alternate []
synonym	"AcAla" EXACT PSI-MOD-label []
synonym	"acetylalanine" EXACT RESID-alternate []
synonym	"MOD_RES N-acetylalanine" EXACT UniProt-feature []
synonym	"N-acetyl-L-alanine" EXACT RESID-name []
synonym	"N-acetylated L-alanine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 8 N 1 O 2"
xref	MassAvg: "114.12"
xref	MassMono: "114.055504"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.51. MOD:00051 N-acetyl-L-aspartic acid

Table 53. Term [MOD:00051]
id	MOD:00051
name	N-acetyl-L-aspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to N-acetyl-L-aspartic acid." [ChEBI:21547, PubMed:1560020, PubMed:2395459, RESID:AA0042]
subset	PSI-MOD-slim
synonym	"(2S)-2-(acetamido)butanedioic acid" EXACT RESID-systematic []
synonym	"2-(acetylamino)butanedioic acid" EXACT RESID-alternate []
synonym	"2-(acetylazanyl)butanedioic acid" EXACT RESID-alternate []
synonym	"AcAsp" EXACT PSI-MOD-label []
synonym	"acetylaspartic acid" EXACT RESID-alternate []
synonym	"MOD_RES N-acetylaspartate" EXACT UniProt-feature []
synonym	"N-acetyl-L-aspartic acid" EXACT RESID-name []
synonym	"N-acetylated L-aspartic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 6 H 8 N 1 O 4"
xref	MassAvg: "158.13"
xref	MassMono: "158.045333"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.52. MOD:00052 N-acetyl-L-cysteine

Table 54. Term [MOD:00052]
id	MOD:00052
name	N-acetyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-acetyl-L-cysteine." [ChEBI:28939, PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:1500421, PubMed:15350136, PubMed:6725286, RESID:AA0043]
comment	incidental to RESID:AA0223
subset	PSI-MOD-slim
synonym	"(2R)-2-acetamido-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-mercaptopropanoic acid" EXACT RESID-alternate []
synonym	"2-acetylamino-3-sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"MOD_RES N-acetylcysteine" EXACT UniProt-feature []
synonym	"N-acetyl-L-cysteine" EXACT RESID-name []
synonym	"N-acetylated cysteine" EXACT PSI-MOD-alternate []
synonym	"N-acetylcysteine" EXACT RESID-alternate []
synonym	"NAcCys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1 S 0"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 8 N 1 O 2 S 1"
xref	MassAvg: "146.18"
xref	MassMono: "146.027574"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00646 acetylated L-cysteine ! acetylated L-cysteine
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.53. MOD:00053 N-acetyl-L-glutamic acid

Table 55. Term [MOD:00053]
id	MOD:00053
name	N-acetyl-L-glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to N-acetyl-L-glutamic acid." [ChEBI:17533, PubMed:6725286, RESID:AA0044]
subset	PSI-MOD-slim
synonym	"(2S)-2-(acetamido)pentanedioic acid" EXACT RESID-systematic []
synonym	"2-(acetylamino)pentanedioic acid" EXACT RESID-alternate []
synonym	"2-(acetylazanyl)pentanedioic acid" EXACT RESID-alternate []
synonym	"acetylglutamic acid" EXACT RESID-alternate []
synonym	"AcGlu" EXACT PSI-MOD-label []
synonym	"MOD_RES N-acetylglutamate" EXACT UniProt-feature []
synonym	"N-acetyl-L-glutamic acid" EXACT RESID-name []
synonym	"N-acetylated L-glutamic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 7 H 10 N 1 O 4"
xref	MassAvg: "172.16"
xref	MassMono: "172.060983"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.54. MOD:00054 N-acetyl-L-glutamine

Table 56. Term [MOD:00054]
id	MOD:00054
name	N-acetyl-L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to N-acetyl-L-glutamine." [RESID:AA0045]
comment	This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S)-2-acetamido-5-pentanediamic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-5-amino-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"2-acetylamino-5-pentanediamic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-5-azanyl-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"acetylglutamine" EXACT RESID-alternate []
synonym	"AcGln" EXACT PSI-MOD-label []
synonym	"N-acetyl-L-glutamine" EXACT RESID-name []
synonym	"N-acetylated L-glutamine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 7 H 11 N 2 O 3"
xref	MassAvg: "171.18"
xref	MassMono: "171.076967"
xref	Origin: "Q"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.55. MOD:00055 N-acetylglycine

Table 57. Term [MOD:00055]
id	MOD:00055
name	N-acetylglycine
def	"A protein modification that effectively converts a glycine residue to N-acetylglycine." [PubMed:272676, PubMed:5545094, PubMed:6754709, RESID:AA0046]
subset	PSI-MOD-slim
synonym	"(acetylamino)acetic acid" EXACT RESID-alternate []
synonym	"(acetylazanyl)ethanoic acid" EXACT RESID-alternate []
synonym	"2-(acetamido)ethanoic acid" EXACT RESID-systematic []
synonym	"2-(acetylamino)ethanoic acid" EXACT RESID-alternate []
synonym	"aceturic acid" EXACT RESID-alternate []
synonym	"AcGly" EXACT PSI-MOD-label []
synonym	"MOD_RES N-acetylglycine" EXACT UniProt-feature []
synonym	"N-acetylated glycine" EXACT PSI-MOD-alternate []
synonym	"N-acetylglycine" EXACT RESID-name []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 4 H 6 N 1 O 2"
xref	MassAvg: "100.10"
xref	MassMono: "100.039853"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.56. MOD:00056 N-acetyl-L-isoleucine

Table 58. Term [MOD:00056]
id	MOD:00056
name	N-acetyl-L-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to N-acetyl-L-isoleucine." [PubMed:8034631, RESID:AA0047]
comment	This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S,3S)-2-acetamido-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-methylpentanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-methylpentanoic acid" EXACT RESID-alternate []
synonym	"acetylisoleucine" EXACT RESID-alternate []
synonym	"AcIle" EXACT PSI-MOD-label []
synonym	"N-acetyl-L-isoleucine" EXACT RESID-name []
synonym	"N-acetylated L-isoleucine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 14 N 1 O 2"
xref	MassAvg: "156.20"
xref	MassMono: "156.102454"
xref	Origin: "I"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.57. MOD:00057 N2-acetyl-L-lysine

Table 59. Term [MOD:00057]
id	MOD:00057
name	N2-acetyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N2-acetyl-L-lysine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, RESID:AA0048]
comment	This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S)-2-acetamido-6-aminohexanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-6-aminohexanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-6-azanylhexanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"N2-acetyl-L-lysine" EXACT RESID-name []
synonym	"N2-acetylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N2-acetyllysine" EXACT RESID-alternate []
synonym	"N2AcLys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 15 N 2 O 2"
xref	MassAvg: "171.22"
xref	MassMono: "171.113353"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00723 N-acetylated L-lysine ! N-acetylated L-lysine
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.58. MOD:00058 N-acetyl-L-methionine

Table 60. Term [MOD:00058]
id	MOD:00058
name	N-acetyl-L-methionine
def	"A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine." [PubMed:7944406, RESID:AA0049]
subset	PSI-MOD-slim
synonym	"(2S)-2-acetamido-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"2-acetylamino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"acetylmethionine" EXACT RESID-alternate []
synonym	"AcMet" EXACT PSI-MOD-label []
synonym	"methionamine" EXACT RESID-alternate []
synonym	"MOD_RES N-acetylmethionine" EXACT UniProt-feature []
synonym	"N-acetyl-L-methionine" EXACT RESID-name []
synonym	"N-acetylated L-methionine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1 S 0"
xref	DiffMono: "42.010565"
xref	Formula: "C 7 H 12 N 1 O 2 S 1"
xref	MassAvg: "174.24"
xref	MassMono: "174.058875"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.59. MOD:00059 N-acetyl-L-proline

Table 61. Term [MOD:00059]
id	MOD:00059
name	N-acetyl-L-proline
def	"A protein modification that effectively converts an L-proline residue to N-acetyl-L-proline." [PubMed:2928307, RESID:AA0050]
subset	PSI-MOD-slim
synonym	"(2S)-1-acetyl-2-pyrrolidinecarboxylic acid" EXACT RESID-systematic []
synonym	"1-acetylproline" EXACT RESID-alternate []
synonym	"acetylproline" EXACT RESID-alternate []
synonym	"MOD_RES N-acetylproline" EXACT UniProt-feature []
synonym	"N-acetyl-L-proline" EXACT RESID-name []
synonym	"N-acetylated L-proline" EXACT PSI-MOD-alternate []
synonym	"N-acetylproline" EXACT RESID-alternate []
synonym	"NAcPro" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 7 H 10 N 1 O 2"
xref	MassAvg: "140.16"
xref	MassMono: "140.071154"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.60. MOD:00060 N-acetyl-L-serine

Table 62. Term [MOD:00060]
id	MOD:00060
name	N-acetyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to N-acetyl-L-serine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, PubMed:1880797, PubMed:2106685, PubMed:6997045, RESID:AA0051]
subset	PSI-MOD-slim
synonym	"(2S)-2-acetamido-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-hydroxypropanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-hydroxypropanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"MOD_RES N-acetylserine" EXACT UniProt-feature []
synonym	"N-acetyl-L-serine" EXACT RESID-name []
synonym	"N-acetylated L-serine" EXACT PSI-MOD-alternate []
synonym	"N-acetylserine" EXACT RESID-alternate []
synonym	"NAcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 8 N 1 O 3"
xref	MassAvg: "130.12"
xref	MassMono: "130.050418"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00647 acetylated L-serine ! acetylated L-serine
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.61. MOD:00061 N-acetyl-L-threonine

Table 63. Term [MOD:00061]
id	MOD:00061
name	N-acetyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to N-acetyl-L-threonine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, PubMed:2106685, PubMed:6997045, RESID:AA0052]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-acetamido-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-hydroxybutanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-hydroxybutanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"MOD_RES N-acetylthreonine" EXACT UniProt-feature []
synonym	"N-acetyl-L-threonine" EXACT RESID-name []
synonym	"N-acetylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"N-acetylthreonine" EXACT RESID-alternate []
synonym	"N-methylcarbonylthreonine" EXACT RESID-alternate []
synonym	"NAcThr" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 6 H 10 N 1 O 3"
xref	MassAvg: "144.15"
xref	MassMono: "144.066068"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01186 acetylated L-threonine ! acetylated L-threonine
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.62. MOD:00062 N-acetyl-L-tyrosine

Table 64. Term [MOD:00062]
id	MOD:00062
name	N-acetyl-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to N-acetyl-L-tyrosine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, PubMed:2506074, PubMed:475783, RESID:AA0053]
synonym	"(2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"AcTyr" EXACT PSI-MOD-label []
synonym	"MOD_RES N-acetyltyrosine" EXACT UniProt-feature []
synonym	"N-acetyl-L-tyrosine" EXACT RESID-name []
synonym	"N-acetylated L-tyrosine" EXACT PSI-MOD-alternate []
synonym	"N-acetyltyrosine" EXACT RESID-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 11 H 12 N 1 O 3"
xref	MassAvg: "206.22"
xref	MassMono: "206.081718"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.63. MOD:00063 N-acetyl-L-valine

Table 65. Term [MOD:00063]
id	MOD:00063
name	N-acetyl-L-valine
def	"A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine." [PubMed:1735421, RESID:AA0054]
subset	PSI-MOD-slim
synonym	"(2S)-2-acetamido-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"2-acetylamino-3-methylbutanoic acid" EXACT RESID-alternate []
synonym	"2-acetylazanyl-3-methylbutanoic acid" EXACT RESID-alternate []
synonym	"AcVal" EXACT PSI-MOD-label []
synonym	"MOD_RES N-acetylvaline" EXACT UniProt-feature []
synonym	"N-acetyl-L-valine" EXACT RESID-name []
synonym	"N-acetylated L-valine" EXACT PSI-MOD-alternate []
synonym	"N-acetylvaline" EXACT RESID-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 7 H 12 N 1 O 2"
xref	MassAvg: "142.18"
xref	MassMono: "142.086804"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.64. MOD:00064 N6-acetyl-L-lysine

Table 66. Term [MOD:00064]
id	MOD:00064
name	N6-acetyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine." [ChEBI:17752, DeltaMass:214, OMSSA:24, PubMed:11369851, PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, PubMed:1680872, PubMed:670159, RESID:AA0055, UniMod:1#K]
subset	PSI-MOD-slim
synonym	"(2S)-6-acetamido-2-aminohexanoic acid" EXACT RESID-systematic []
synonym	"6-acetylamino-2-aminohexanoic acid" EXACT RESID-alternate []
synonym	"6-acetylazanyl-2-aminohexanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"acetylk" EXACT OMSSA-label []
synonym	"epsilon-acetyllysine" EXACT RESID-alternate []
synonym	"MOD_RES N6-acetyllysine" EXACT UniProt-feature []
synonym	"N(zeta)-acetyllysine" EXACT RESID-alternate []
synonym	"N6-acetyl-L-lysine" EXACT RESID-name []
synonym	"N6-acetylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6AcLys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 14 N 2 O 2"
xref	MassAvg: "170.21"
xref	MassMono: "170.105528"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00723 N-acetylated L-lysine ! N-acetylated L-lysine
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.65. MOD:00065 S-acetyl-L-cysteine

Table 67. Term [MOD:00065]
id	MOD:00065
name	S-acetyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-acetyl-L-cysteine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:1310545, PubMed:14730666, PubMed:15350136, RESID:AA0056, UniMod:1#C]
subset	PSI-MOD-slim
synonym	"(2R)-3-acetylsulfanyl-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(acetylthio)propanoic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-(acetylsulfanyl)propanoic acid" EXACT RESID-alternate []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"ACT_SITE S-acetylcysteine intermediate" EXACT UniProt-feature []
synonym	"cysteine acetate thioester" EXACT RESID-alternate []
synonym	"S-acetyl-L-cysteine" EXACT RESID-name []
synonym	"S-acetylcysteine" EXACT RESID-alternate []
synonym	"SAcCys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1 S 0"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 7 N 1 O 2 S 1"
xref	MassAvg: "145.18"
xref	MassMono: "145.019749"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00645 S-acetylated residue ! S-acetylated residue
is_a	MOD:00646 acetylated L-cysteine ! acetylated L-cysteine

2.66. MOD:00066 N-formylglycine

Table 68. Term [MOD:00066]
id	MOD:00066
name	N-formylglycine
def	"A protein modification that effectively converts a glycine residue to N-formylglycine." [PubMed:5139483, RESID:AA0057]
synonym	"(formylamino)acetic acid" EXACT RESID-alternate []
synonym	"(formylamino)ethanoic acid" EXACT RESID-systematic []
synonym	"(formylazanyl)ethanoic acid" EXACT RESID-alternate []
synonym	"2-formamidoacetic acid" EXACT RESID-alternate []
synonym	"2-formamidoethanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N-formylglycine" EXACT UniProt-feature []
synonym	"N(alpha)-formylglycine" EXACT RESID-alternate []
synonym	"N-formylated glycine" EXACT PSI-MOD-alternate []
synonym	"N-formylglycine" EXACT RESID-name []
synonym	"NFoGly" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 3 H 4 N 1 O 2"
xref	MassAvg: "86.07"
xref	MassMono: "86.024203"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.67. MOD:00067 N-D-glucuronoylglycine

Table 69. Term [MOD:00067]
id	MOD:00067
name	N-D-glucuronoylglycine
def	"A protein modification that effectively converts a glycine residue to N-D-glucuronoylglycine." [OMSSA:50, PubMed:10858503, PubMed:12716131, PubMed:6493057, PubMed:7398618, RESID:AA0058]
synonym	"2-(glucuronoylamino)ethanoic acid" EXACT RESID-systematic []
synonym	"Glucuronyl" RELATED PSI-MS-label []
synonym	"MOD_RES N-D-glucuronoyl glycine" EXACT UniProt-feature []
synonym	"N-D-glucuronoyl-glycine" EXACT RESID-name []
synonym	"N-D-glucuronyl-glycine" EXACT RESID-alternate []
synonym	"NGlcAGly" EXACT PSI-MOD-label []
synonym	"ntermpepglucuronylg" EXACT OMSSA-label []
xref	DiffAvg: "176.12"
xref	DiffFormula: "C 6 H 8 N 0 O 6"
xref	DiffMono: "176.032088"
xref	Formula: "C 8 H 12 N 1 O 7"
xref	MassAvg: "234.18"
xref	MassMono: "234.061377"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00447 N-glucuronylated residue ! N-glucuronylated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.68. MOD:00068 N-myristoylglycine

Table 70. Term [MOD:00068]
id	MOD:00068
name	N-myristoylglycine
def	"A protein modification that effectively converts a glycine residue to N-myristoylglycine." [OMSSA:80, PubMed:11955007, PubMed:11955008, PubMed:1326520, PubMed:1386601, PubMed:6436247, PubMed:7543369, RESID:AA0059, UniMod:45#G]
subset	PSI-MOD-slim
synonym	"(tetradecanoylamino)ethanoic acid" EXACT RESID-systematic []
synonym	"LIPID N-myristoyl glycine" EXACT UniProt-feature []
synonym	"Myristoyl" RELATED PSI-MS-label []
synonym	"Myristoylation" RELATED UniMod-description []
synonym	"N-(1-oxotetradecyl)glycine" EXACT RESID-alternate []
synonym	"N-(C14:0 aliphatic acyl)glycine" EXACT PSI-MOD-alternate []
synonym	"N-myristoyl-glycine" EXACT RESID-name []
synonym	"N-myristoylated glycine" EXACT PSI-MOD-alternate []
synonym	"N-myristylglycine" EXACT RESID-alternate []
synonym	"N-tetradecanoylglycine" EXACT RESID-alternate []
synonym	"NMyrGly" EXACT PSI-MOD-label []
synonym	"ntermpepmyristoylationg" EXACT OMSSA-label []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 N 0 O 1"
xref	DiffMono: "210.198365"
xref	Formula: "C 16 H 30 N 1 O 2"
xref	MassAvg: "268.42"
xref	MassMono: "268.227654"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00650 N-myristoylated residue ! N-myristoylated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.69. MOD:00069 N-palmitoyl-L-cysteine

Table 71. Term [MOD:00069]
id	MOD:00069
name	N-palmitoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine." [PubMed:10896212, PubMed:4575979, PubMed:9056182, PubMed:9593755, RESID:AA0060]
comment	incidental to RESID:AA0107 incidental to RESID:AA0309
subset	PSI-MOD-slim
synonym	"(2R)-2-hexadecanoylamino-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-hexadecanamido-3-sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-hexadecanoylamino-3-mercaptopropanoic acid" EXACT RESID-alternate []
synonym	"LIPID N-palmitoyl cysteine" EXACT UniProt-feature []
synonym	"N-(1-oxahexadecyl)-L-cysteine" EXACT RESID-alternate []
synonym	"N-palmitoyl-L-cysteine" EXACT RESID-name []
synonym	"N-palmitoylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"NPamCys" EXACT PSI-MOD-label []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "C 19 H 36 N 1 O 2 S 1"
xref	MassAvg: "342.56"
xref	MassMono: "342.246675"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01684 palmitoylated-L-cysteine ! palmitoylated-L-cysteine
is_a	MOD:01685 alpha-amino palmitoylated residue ! alpha-amino palmitoylated residue

2.70. MOD:00070 N-methyl-L-alanine

Table 72. Term [MOD:00070]
id	MOD:00070
name	N-methyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N-methyl-L-alanine." [ChEBI:17519, PubMed:323502, PubMed:337304, PubMed:7007074, RESID:AA0061]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-methylaminopropanoic acid" EXACT RESID-systematic []
synonym	"2-methylazanylpropanoic acid" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N-methylalanine" EXACT UniProt-feature []
synonym	"N-methyl-L-alanine" EXACT RESID-name []
synonym	"N-methylalanine" EXACT RESID-alternate []
synonym	"N-methylated L-alanine" EXACT PSI-MOD-alternate []
synonym	"NMe1Ala" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 4 H 7 N 1 O 1"
xref	MassAvg: "85.11"
xref	MassMono: "85.052764"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01461 N-methylated alanine ! N-methylated alanine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.71. MOD:00071 N,N,N-trimethyl-L-alanine

Table 73. Term [MOD:00071]
id	MOD:00071
name	N,N,N-trimethyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N,N,N-trimethyl-L-alanine." [PubMed:12590383, PubMed:332162, PubMed:3979397, PubMed:6778808, PubMed:7715456, RESID:AA0062]
subset	PSI-MOD-slim
synonym	"(1S)-1-carboxy-N,N,N-trimethylethanaminium" EXACT RESID-systematic []
synonym	"(1S)-1-carboxy-N,N,N-trimethylethanazanium" EXACT RESID-alternate []
synonym	"(2S)-2-(trimethylammonio)propanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N,N,N-trimethylalanine" EXACT UniProt-feature []
synonym	"N,N,N-trimethyl-L-alanine" EXACT RESID-name []
synonym	"N,N,N-trimethylalanine cation" EXACT RESID-alternate []
synonym	"N,N,N-trimethylalaninium" EXACT RESID-alternate []
synonym	"N,N,N-trimethylated L-alanine" EXACT PSI-MOD-alternate []
synonym	"N2Me3+Ala" EXACT PSI-MOD-label []
synonym	"NMe3Ala" EXACT PSI-MOD-label []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 13 N 1 O 1"
xref	MassAvg: "115.18"
xref	MassMono: "115.099165"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01461 N-methylated alanine ! N-methylated alanine
is_a	MOD:01698 alpha-amino trimethylated protonated-residue ! alpha-amino trimethylated protonated-residue

2.72. MOD:00072 N-methylglycine

Table 74. Term [MOD:00072]
id	MOD:00072
name	N-methylglycine
def	"A protein modification that effectively converts a glycine residue to N-methylglycine." [ChEBI:15611, DeltaMass:0, PubMed:1593629, RESID:AA0063]
comment	DeltaMass also has an entry for the free amino acid. Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
synonym	"L-sarcosine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methylaminoacetic acid" EXACT RESID-alternate []
synonym	"methylaminoethanoic acid" EXACT RESID-systematic []
synonym	"Methylation" RELATED UniMod-description []
synonym	"N-methylated glycine" EXACT PSI-MOD-alternate []
synonym	"N-methylglycine" EXACT RESID-name []
synonym	"NMe1Gly" EXACT PSI-MOD-label []
synonym	"Sar" EXACT DeltaMass-label []
synonym	"Sarcosine" EXACT DeltaMass-label []
synonym	"Sarcosyl" EXACT DeltaMass-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00570 residues isobaric at 71.037114 Da ! residues isobaric at 71.037114 Da
is_a	MOD:00714 methylated glycine ! methylated glycine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.73. MOD:00073 N-methyl-L-methionine

Table 75. Term [MOD:00073]
id	MOD:00073
name	N-methyl-L-methionine
def	"A protein modification that effectively converts an L-methionine residue to N-methyl-L-methionine." [DeltaMass:169, PubMed:323502, PubMed:3298225, RESID:AA0064]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-methylamino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-methylamino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methyl Methionyl" EXACT DeltaMass-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N-methylmethionine" EXACT UniProt-feature []
synonym	"N-methyl-L-methionine" EXACT RESID-name []
synonym	"N-methylated L-methionine" EXACT PSI-MOD-alternate []
synonym	"N-methylmethionine" EXACT RESID-alternate []
synonym	"NMe1Met" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 11 N 1 O 1 S 1"
xref	MassAvg: "145.22"
xref	MassMono: "145.056135"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01463 N-methylated methionine ! N-methylated methionine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.74. MOD:00074 N-methyl-L-phenylalanine

Table 76. Term [MOD:00074]
id	MOD:00074
name	N-methyl-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine." [PubMed:2577730, PubMed:413571, RESID:AA0065]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-methylamino-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N-methylphenylalanine" EXACT UniProt-feature []
synonym	"N-methyl-L-phenylalanine" EXACT RESID-name []
synonym	"N-methylated L-phenylalanine" EXACT PSI-MOD-alternate []
synonym	"N-methylphenylalanine" EXACT RESID-alternate []
synonym	"NMe1Phe" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 10 H 11 N 1 O 1"
xref	MassAvg: "161.20"
xref	MassMono: "161.084064"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01063 monomethylated phenylalanine ! monomethylated phenylalanine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.75. MOD:00075 N,N-dimethyl-L-proline

Table 77. Term [MOD:00075]
id	MOD:00075
name	N,N-dimethyl-L-proline
def	"A protein modification that effectively converts an L-proline residue to N,N-dimethyl-L-proline." [ChEBI:21451, PubMed:12964758, PubMed:14570711, PubMed:193025, PubMed:3882426, PubMed:6254758, RESID:AA0066, UniMod:529]
comment	UniMod terminal specification corrected [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-carboxy-1,1-dimethylpyrrolidinium" EXACT RESID-systematic []
synonym	"1,1-dimethyl-L-prolinium" EXACT RESID-alternate []
synonym	"Delta:H(5)C(2)" RELATED UniMod-interim []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"Dimethylation of proline residue" RELATED UniMod-description []
synonym	"MOD_RES N,N-dimethylproline" EXACT UniProt-feature []
synonym	"N,N-dimethyl-L-proline" EXACT RESID-name []
synonym	"N,N-dimethyl-L-prolinium" EXACT RESID-alternate []
synonym	"N,N-dimethylated L-proline" EXACT PSI-MOD-alternate []
synonym	"NMe2Pro" EXACT PSI-MOD-label []
synonym	"stachydrin" EXACT RESID-alternate []
xref	DiffAvg: "29.06"
xref	DiffFormula: "C 2 H 5 N 0 O 0"
xref	DiffMono: "29.038577"
xref	FormalCharge: "1+"
xref	Formula: "C 7 H 13 N 1 O 1"
xref	MassAvg: "127.19"
xref	MassMono: "127.099165"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00710 protonated-dimethylated residue ! protonated-dimethylated residue
is_a	MOD:01462 N-methylated proline ! N-methylated proline

2.76. MOD:00076 symmetric dimethyl-L-arginine

Table 78. Term [MOD:00076]
id	MOD:00076
name	symmetric dimethyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine." [PubMed:12964758, PubMed:14570711, PubMed:15835918, PubMed:2426402, PubMed:5128665, RESID:AA0067, UniMod:36#R]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acid" EXACT RESID-systematic []
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"MOD_RES Omega-N-methylated arginine" EXACT UniProt-feature []
synonym	"MOD_RES Symmetric dimethylarginine" EXACT UniProt-feature []
synonym	"N3,N4-dimethylarginine" EXACT RESID-alternate []
synonym	"N5-[(methylamino)(methylimino)methyl]ornithine" EXACT RESID-alternate []
synonym	"NG,N’G-dimethylarginine" EXACT RESID-alternate []
synonym	"NoNo’Me2Arg" EXACT PSI-MOD-label []
synonym	"omega-N,omega-N'-dimethyl-L-arginine" EXACT RESID-name []
synonym	"omega-N,omega-N'-dimethylated L-arginine" EXACT PSI-MOD-alternate []
synonym	"symmetric dimethylarginine" EXACT RESID-alternate []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 4 O 1"
xref	MassAvg: "184.24"
xref	MassMono: "184.132411"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00783 dimethylated L-arginine ! dimethylated L-arginine

2.77. MOD:00077 asymmetric dimethyl-L-arginine

Table 79. Term [MOD:00077]
id	MOD:00077
name	asymmetric dimethyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine." [ChEBI:17929, PubMed:11152131, PubMed:12964758, PubMed:14570711, PubMed:15835918, PubMed:3032834, RESID:AA0068, UniMod:36#R]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"asymmetric dimethylarginine" EXACT RESID-alternate []
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"MOD_RES Asymmetric dimethylarginine" EXACT UniProt-feature []
synonym	"MOD_RES Omega-N-methylated arginine" EXACT UniProt-feature []
synonym	"N5-[(dimethylamino)(imino)methyl]ornithine" EXACT RESID-alternate []
synonym	"NG,NG-dimethylarginine" EXACT RESID-alternate []
synonym	"NoNoMe2Arg" EXACT PSI-MOD-label []
synonym	"omega-N,omega-N-dimethlyated L-arginine" EXACT PSI-MOD-alternate []
synonym	"omega-N,omega-N-dimethyl-L-arginine" EXACT RESID-name []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 4 O 1"
xref	MassAvg: "184.24"
xref	MassMono: "184.132411"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00783 dimethylated L-arginine ! dimethylated L-arginine

2.78. MOD:00078 omega-N-methyl-L-arginine

Table 80. Term [MOD:00078]
id	MOD:00078
name	omega-N-methyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine." [PubMed:11875433, PubMed:15835918, PubMed:2426402, PubMed:5128665, RESID:AA0069]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-[(imino(methylamino)methyl)amino]pentanoic acid" EXACT RESID-systematic []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Omega-N-methylarginine" EXACT UniProt-feature []
synonym	"MOD_RES Omega-N-methylated arginine" EXACT UniProt-feature []
synonym	"NG-methylarginine" EXACT RESID-alternate []
synonym	"NoMeArg" EXACT PSI-MOD-label []
synonym	"omega-N-methyl-L-arginine" EXACT RESID-name []
synonym	"omega-N-methylated L-arginine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00414 monomethylated L-arginine ! monomethylated L-arginine
is_a	MOD:00602 N-methylated residue ! N-methylated residue

2.79. MOD:00079 N4-methyl-L-asparagine

Table 81. Term [MOD:00079]
id	MOD:00079
name	N4-methyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-methyl-L-asparagine." [OMSSA:75, PubMed:11875433, PubMed:2356973, PubMed:3782095, RESID:AA0070, UniMod:34#N]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-N4-methylbutanediamic acid" EXACT RESID-systematic []
synonym	"beta-aspartyl methylamide" EXACT RESID-alternate []
synonym	"beta-methylasparagine" RELATED RESID-misnomer []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"methyln" EXACT OMSSA-label []
synonym	"MOD_RES N4-methylasparagine" EXACT UniProt-feature []
synonym	"N(gamma)-methylasparagine" EXACT RESID-alternate []
synonym	"N-methylasparagine" EXACT RESID-alternate []
synonym	"N4-methyl-L-asparagine" EXACT RESID-name []
synonym	"N4-methylated L-asparagine" EXACT PSI-MOD-alternate []
synonym	"N4Me1Asn" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 5 H 8 N 2 O 2"
xref	MassAvg: "128.13"
xref	MassMono: "128.058578"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00673 methylated asparagine ! methylated asparagine
is_a	MOD:00894 residues isobaric at 128.058578 Da ! residues isobaric at 128.058578 Da

2.80. MOD:00080 N5-methyl-L-glutamine

Table 82. Term [MOD:00080]
id	MOD:00080
name	N5-methyl-L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to N5-methyl-L-glutamine." [ChEBI:17592, DeltaMass:166, PubMed:11118225, PubMed:11875433, PubMed:365579, RESID:AA0071]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-methylamino-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N5-methylpentanediamic acid" EXACT RESID-alternate []
synonym	"gamma-methylglutamine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N5-methylglutamine" EXACT UniProt-feature []
synonym	"N(delta)-methylglutamine" EXACT RESID-alternate []
synonym	"N-methylglutamine" EXACT RESID-alternate []
synonym	"N5-methyl-L-glutamine" EXACT RESID-name []
synonym	"N5-methylated L-glutamine" EXACT PSI-MOD-alternate []
synonym	"N5Me1Gln" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 10 N 2 O 2"
xref	MassAvg: "142.16"
xref	MassMono: "142.074228"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00722 monomethylated L-glutamine ! monomethylated L-glutamine

2.81. MOD:00081 L-glutamic acid 5-methyl ester (Glu)

Table 83. Term [MOD:00081]
id	MOD:00081
name	L-glutamic acid 5-methyl ester (Glu)
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-methyl ester." [DeltaMass:167, OMSSA:17, OMSSA:70, PubMed:16888, PubMed:6300110, RESID:AA0072#GLU, UniMod:34#E]
comment	DeltaMass gives the formula "C 6 H 9 O 1 N 3" with mass 143 (formula incorrect, N and O reversed) [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-methoxy-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(5)-methyl L-hydrogen glutamate" EXACT RESID-alternate []
synonym	"2-aminopentanedioic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"5-methyl esterified L-glutamic acid" EXACT PSI-MOD-alternate []
synonym	"5-methyl L-2-aminoglutarate" EXACT RESID-alternate []
synonym	"5-methyl L-glutamate" EXACT RESID-alternate []
synonym	"glutamic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"glutamic acid gamma-methyl ester" EXACT RESID-alternate []
synonym	"L-glutamic acid 5-methyl ester" EXACT RESID-name []
synonym	"meestere" EXACT OMSSA-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methyl ester" RELATED UniMod-alternate []
synonym	"Methylation" RELATED UniMod-description []
synonym	"methyle" EXACT OMSSA-label []
synonym	"MOD_RES Glutamate methyl ester (Glu)" EXACT UniProt-feature []
synonym	"O-methyl Glutamyl" EXACT DeltaMass-label []
synonym	"O5MeGlu" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 9 N 1 O 3"
xref	MassAvg: "143.14"
xref	MassMono: "143.058243"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01453 L-glutamic acid 5-methyl ester ! L-glutamic acid 5-methyl ester

2.82. MOD:00082 3'-methyl-L-histidine

Table 84. Term [MOD:00082]
id	MOD:00082
name	3'-methyl-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to pros-methyl-L-histidine (N-pi-methyl-L-histidine, 3'-methyl-L-histidine)." [PubMed:10660523, PubMed:11875433, PubMed:3467365, PubMed:6692818, PubMed:8076, PubMed:8645219, RESID:AA0073]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(3-methyl-3H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1-methylhistidine" RELATED RESID-misnomer []
synonym	"3'-methyl-L-histidine" EXACT RESID-name []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Pros-methylhistidine" EXACT UniProt-feature []
synonym	"N(delta)-methylhistidine" EXACT RESID-alternate []
synonym	"N(pi)-methylhistidine" EXACT RESID-alternate []
synonym	"NpMeHis" EXACT PSI-MOD-label []
synonym	"pros-methylated L-histidine" EXACT PSI-MOD-alternate []
synonym	"pros-methylhistidine" EXACT RESID-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 9 N 3 O 1"
xref	MassAvg: "151.17"
xref	MassMono: "151.074562"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00724 N-methylated L-histidine ! N-methylated L-histidine

2.83. MOD:00083 N6,N6,N6-trimethyl-L-lysine

Table 85. Term [MOD:00083]
id	MOD:00083
name	N6,N6,N6-trimethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine." [ChEBI:17311, PubMed:12590383, PubMed:3145979, PubMed:4304194, PubMed:6778808, PubMed:7093227, PubMed:8453381, RESID:AA0074]
comment	DeltaMass calculates the mass difference from protonated lysine rather than neutral lysine; for trimethylated lysine starting from protonated lysine see MOD:00855
subset	PSI-MOD-slim
synonym	"(5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium" EXACT RESID-systematic []
synonym	"2-amino-6-(trimethylammonio)hexanoic acid" EXACT RESID-alternate []
synonym	"5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium" EXACT RESID-alternate []
synonym	"epsilon-trimethyllysine" EXACT RESID-alternate []
synonym	"MOD_RES N6,N6,N6-trimethyllysine" EXACT UniProt-feature []
synonym	"N(zeta)-trimethyllysine" EXACT RESID-alternate []
synonym	"N-trimethylation (of lysine)" EXACT DeltaMass-label []
synonym	"N6,N6,N6-trimethyl-L-lysine" EXACT RESID-name []
synonym	"N6,N6,N6-trimethylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6,N6,N6-trimethyllysin-N6-ium" EXACT RESID-alternate []
synonym	"N6,N6,N6-trimethyllysine cation" EXACT RESID-alternate []
synonym	"N6Me3+Lys" EXACT PSI-MOD-label []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "C 9 H 19 N 2 O 1"
xref	MassAvg: "171.26"
xref	MassMono: "171.149190"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00663 methylated lysine ! methylated lysine
is_a	MOD:00711 trimethylated protonated-residue ! trimethylated protonated-residue

2.84. MOD:00084 N6,N6-dimethyl-L-lysine

Table 86. Term [MOD:00084]
id	MOD:00084
name	N6,N6-dimethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine." [OMSSA:36, PubMed:10550045, PubMed:12964758, PubMed:14570711, PubMed:3100523, PubMed:8453381, RESID:AA0075, UniMod:36#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(dimethylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"dimethylk" EXACT OMSSA-label []
synonym	"epsilon-dimethyllysine" EXACT RESID-alternate []
synonym	"lysine derivative Lys(y)" EXACT RESID-alternate []
synonym	"MOD_RES N6,N6-dimethyllysine" EXACT UniProt-feature []
synonym	"N(zeta)-dimethyllysine" EXACT RESID-alternate []
synonym	"N6,N6-dimethyl-L-lysine" EXACT RESID-name []
synonym	"N6,N6-dimethylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6Me2Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 2 O 1"
xref	MassAvg: "156.23"
xref	MassMono: "156.126263"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00429 dimethylated residue ! dimethylated residue
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00663 methylated lysine ! methylated lysine

2.85. MOD:00085 N6-methyl-L-lysine

Table 87. Term [MOD:00085]
id	MOD:00085
name	N6-methyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine." [ChEBI:17604, DeltaMass:165, PubMed:11875433, PubMed:3926756, RESID:AA0076, UniMod:34#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-methylaminohexanoic acid" EXACT RESID-systematic []
synonym	"epsilon-methyllysine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N6-methyllysine" EXACT UniProt-feature []
synonym	"N(zeta)-methyllysine" EXACT RESID-alternate []
synonym	"N-methyl Lysyl" EXACT DeltaMass-label []
synonym	"N6-methyl-L-lysine" EXACT RESID-name []
synonym	"N6-methylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6Me1Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 2 O 1"
xref	MassAvg: "142.20"
xref	MassMono: "142.110613"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:01683 monomethylated L-lysine ! monomethylated L-lysine

2.86. MOD:00086 N6-palmitoyl-L-lysine

Table 88. Term [MOD:00086]
id	MOD:00086
name	N6-palmitoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-palmitoyl-L-lysine." [OMSSA:93, PubMed:2498336, PubMed:7801126, PubMed:7939682, RESID:AA0077, UniMod:47#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(hexadecanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-6-(hexadecanamido)hexanoic acid" EXACT RESID-alternate []
synonym	"epsilon-palmitoyllysine" EXACT RESID-alternate []
synonym	"LIPID N6-palmitoyl lysine" EXACT UniProt-feature []
synonym	"N(zeta)-palmitoyllysine" EXACT RESID-alternate []
synonym	"N6-(1-oxohexadecyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-palmitoyl-L-lysine" EXACT RESID-name []
synonym	"N6-palmitoylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6PamLys" EXACT PSI-MOD-label []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"palmitoylationk" EXACT OMSSA-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "C 22 H 42 N 2 O 2"
xref	MassAvg: "366.59"
xref	MassMono: "366.324629"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00651 N-palmitoylated residue ! N-palmitoylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.87. MOD:00087 N6-myristoyl-L-lysine

Table 89. Term [MOD:00087]
id	MOD:00087
name	N6-myristoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-myristoyl-L-lysine." [OMSSA:81, PubMed:1402651, PubMed:8346241, RESID:AA0078, UniMod:45#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(tetradecanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-6-(tetradecanamido)hexanoic acid" EXACT RESID-alternate []
synonym	"epsilon-myristoyllysine" EXACT RESID-alternate []
synonym	"LIPID N6-myristoyl lysine" EXACT UniProt-feature []
synonym	"Myristoyl" RELATED PSI-MS-label []
synonym	"Myristoylation" RELATED UniMod-description []
synonym	"myristoylationk" EXACT OMSSA-label []
synonym	"N(zeta)-myristoyllysine" EXACT RESID-alternate []
synonym	"N6-(1-oxotetradecyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-(C14:0 aliphatic acyl)lysine" EXACT PSI-MOD-alternate []
synonym	"N6-myristoyl-L-lysine" EXACT RESID-name []
synonym	"N6-myristoylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6MyrLys" EXACT PSI-MOD-label []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 N 0 O 1"
xref	DiffMono: "210.198365"
xref	Formula: "C 20 H 38 N 2 O 2"
xref	MassAvg: "338.54"
xref	MassMono: "338.293328"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00650 N-myristoylated residue ! N-myristoylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.88. MOD:00088 O-palmitoyl-L-threonine

Table 90. Term [MOD:00088]
id	MOD:00088
name	O-palmitoyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-palmitoyl-L-threonine." [OMSSA:95, PubMed:6642431, PubMed:8413602, RESID:AA0079, UniMod:47#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(hexadecanoyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"L-threonine hexadecanoate ester" EXACT RESID-alternate []
synonym	"LIPID O-palmitoyl threonine" EXACT UniProt-feature []
synonym	"O-palmitoyl-L-threonine" EXACT RESID-name []
synonym	"O-palmitoylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"O3-palmitoyl-threonine" EXACT RESID-alternate []
synonym	"OPamThr" EXACT PSI-MOD-label []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"palmitoylationt" EXACT OMSSA-label []
synonym	"threonine palmitate ester" EXACT RESID-alternate []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "C 20 H 37 N 1 O 3"
xref	MassAvg: "339.52"
xref	MassMono: "339.277344"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00652 O-palmitoylated residue ! O-palmitoylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.89. MOD:00089 O-palmitoyl-L-serine

Table 91. Term [MOD:00089]
id	MOD:00089
name	O-palmitoyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-palmitoyl-L-serine." [OMSSA:94, PubMed:3467339, RESID:AA0080, UniMod:47#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(hexadecanoyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE O-palmitoyl serine intermediate" EXACT UniProt-feature []
synonym	"L-serine hexadecanoate ester" EXACT RESID-alternate []
synonym	"LIPID O-palmitoyl serine" EXACT UniProt-feature []
synonym	"O-palmitoyl-L-serine" EXACT RESID-name []
synonym	"O-palmitoylated L-serine" EXACT PSI-MOD-alternate []
synonym	"O3-palmitoyl-serine" EXACT RESID-alternate []
synonym	"OPamSer" EXACT PSI-MOD-label []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"palmitoylations" EXACT OMSSA-label []
synonym	"serine palmitate ester" EXACT RESID-alternate []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "C 19 H 35 N 1 O 3"
xref	MassAvg: "325.49"
xref	MassMono: "325.261694"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00652 O-palmitoylated residue ! O-palmitoylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.90. MOD:00090 L-alanine amide

Table 92. Term [MOD:00090]
id	MOD:00090
name	L-alanine amide
def	"A protein modification that effectively converts an L-alanine residue to L-alanine amide." [PubMed:1377792, PubMed:2069951, PubMed:8472537, PubMed:952951, RESID:AA0081]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminopropanamide" EXACT RESID-systematic []
synonym	"AlaN" EXACT PSI-MOD-label []
synonym	"alaninamide" EXACT RESID-alternate []
synonym	"amidated L-alanine" EXACT PSI-MOD-alternate []
synonym	"L-alanine amide" EXACT RESID-name []
synonym	"MOD_RES Alanine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 3 H 7 N 2 O 1"
xref	MassAvg: "87.10"
xref	MassMono: "87.055838"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.91. MOD:00091 L-arginine amide

Table 93. Term [MOD:00091]
id	MOD:00091
name	L-arginine amide
def	"A protein modification that effectively converts an L-arginine residue to L-arginine amide." [PubMed:2229025, PubMed:2753890, PubMed:743209, RESID:AA0082]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-[(diaminomethylidene)amino]pentanamide" EXACT RESID-systematic []
synonym	"2-amino-5-carbamimidamidopentanamide" EXACT RESID-alternate []
synonym	"2-amino-5-guanidinopentanamide" EXACT RESID-alternate []
synonym	"amidated L-arginine" EXACT PSI-MOD-alternate []
synonym	"argininamide" EXACT RESID-alternate []
synonym	"ArgN" EXACT PSI-MOD-label []
synonym	"L-arginine amide" EXACT RESID-name []
synonym	"MOD_RES Arginine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 6 H 14 N 5 O 1"
xref	MassAvg: "172.21"
xref	MassMono: "172.119835"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.92. MOD:00092 L-asparagine amide

Table 94. Term [MOD:00092]
id	MOD:00092
name	L-asparagine amide
def	"A protein modification that effectively converts an L-asparagine residue to L-asparagine amide." [PubMed:2753132, PubMed:279902, PubMed:3415690, RESID:AA0083]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminobutanediamide" EXACT RESID-systematic []
synonym	"amidated L-asparagine" EXACT PSI-MOD-alternate []
synonym	"AsnN" EXACT PSI-MOD-label []
synonym	"asparaginamide" EXACT RESID-alternate []
synonym	"L-asparagine amide" EXACT RESID-name []
synonym	"MOD_RES Asparagine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 4 H 8 N 3 O 2"
xref	MassAvg: "130.13"
xref	MassMono: "130.061652"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.93. MOD:00093 L-aspartic acid 1-amide

Table 95. Term [MOD:00093]
id	MOD:00093
name	L-aspartic acid 1-amide
def	"A protein modification that effectively converts an L-aspartic acid residue to L-aspartic acid 1-amide." [PubMed:2542051, RESID:AA0084]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-1-butanediamic acid" EXACT RESID-systematic []
synonym	"1-amidated L-aspartic acid" EXACT PSI-MOD-alternate []
synonym	"3,4-diamino-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"3-amino-succinamic acid" EXACT RESID-alternate []
synonym	"alpha-asparagine" EXACT RESID-alternate []
synonym	"AspN" EXACT PSI-MOD-label []
synonym	"isoasparagine" EXACT RESID-alternate []
synonym	"L-aspartic acid 1-amide" EXACT RESID-name []
synonym	"MOD_RES Aspartic acid 1-amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 4 H 7 N 2 O 3"
xref	MassAvg: "131.11"
xref	MassMono: "131.045667"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.94. MOD:00094 L-cysteine amide

Table 96. Term [MOD:00094]
id	MOD:00094
name	L-cysteine amide
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine amide." [PubMed:1892838, PubMed:7149738, RESID:AA0085]
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-sulfanylpropanamide" EXACT RESID-systematic []
synonym	"2-amino-3-mercaptopropanamide" EXACT RESID-alternate []
synonym	"amidated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"CysN" EXACT PSI-MOD-label []
synonym	"cysteinamide" EXACT RESID-alternate []
synonym	"L-cysteine amide" EXACT RESID-name []
synonym	"MOD_RES Cysteine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1 S 0"
xref	DiffMono: "-0.984016"
xref	Formula: "C 3 H 7 N 2 O 1 S 1"
xref	MassAvg: "119.16"
xref	MassMono: "119.027909"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.95. MOD:00095 L-glutamine amide

Table 97. Term [MOD:00095]
id	MOD:00095
name	L-glutamine amide
def	"A protein modification that effectively converts an L-glutamine residue to L-glutamine amide." [PubMed:7673220, PubMed:9048550, RESID:AA0086]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminopentanediamide" EXACT RESID-systematic []
synonym	"amidated L-glutamine" EXACT PSI-MOD-alternate []
synonym	"GlnN" EXACT PSI-MOD-label []
synonym	"glutaminamide" EXACT RESID-alternate []
synonym	"L-glutamine amide" EXACT RESID-name []
synonym	"MOD_RES Glutamine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 5 H 10 N 3 O 2"
xref	MassAvg: "144.15"
xref	MassMono: "144.077302"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.96. MOD:00096 L-glutamic acid 1-amide

Table 98. Term [MOD:00096]
id	MOD:00096
name	L-glutamic acid 1-amide
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamic acid 1-amide." [PubMed:1093875, PubMed:14550575, RESID:AA0087]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-1-pentanediamic acid" EXACT RESID-systematic []
synonym	"1-amidated L-glutamic acid" EXACT PSI-MOD-alternate []
synonym	"4,5-diamino-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"GluN" EXACT PSI-MOD-label []
synonym	"isoglutamine" EXACT RESID-alternate []
synonym	"L-glutamic acid 1-amide" EXACT RESID-name []
synonym	"MOD_RES Glutamic acid 1-amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 5 H 9 N 2 O 3"
xref	MassAvg: "145.14"
xref	MassMono: "145.061317"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.97. MOD:00097 glycine amide

Table 99. Term [MOD:00097]
id	MOD:00097
name	glycine amide
def	"A protein modification that effectively converts a glycine residue to glycine amide." [PubMed:13591312, RESID:AA0088]
subset	PSI-MOD-slim
synonym	"2-aminoacetamide" EXACT RESID-alternate []
synonym	"2-aminoethanamide" EXACT RESID-systematic []
synonym	"2-azanylethanamide" EXACT RESID-alternate []
synonym	"amidated glycine" EXACT PSI-MOD-alternate []
synonym	"glycinamide" EXACT RESID-alternate []
synonym	"glycine amide" EXACT RESID-name []
synonym	"GlyN" EXACT PSI-MOD-label []
synonym	"MOD_RES Glycine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 2 H 5 N 2 O 1"
xref	MassAvg: "73.07"
xref	MassMono: "73.040188"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.98. MOD:00098 L-histidine amide

Table 100. Term [MOD:00098]
id	MOD:00098
name	L-histidine amide
def	"A protein modification that effectively converts an L-histidine residue to L-histidine amide." [PubMed:2153586, PubMed:2307683, PubMed:2839478, RESID:AA0089]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1H-imidazol-4-yl)propanamide" EXACT RESID-systematic []
synonym	"amidated L-histidine" EXACT PSI-MOD-alternate []
synonym	"HisN" EXACT PSI-MOD-label []
synonym	"histidinamide" EXACT RESID-alternate []
synonym	"L-histidine amide" EXACT RESID-name []
synonym	"MOD_RES Histidine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 6 H 9 N 4 O 1"
xref	MassAvg: "153.16"
xref	MassMono: "153.077636"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.99. MOD:00099 L-isoleucine amide

Table 101. Term [MOD:00099]
id	MOD:00099
name	L-isoleucine amide
def	"A protein modification that effectively converts an L-isoleucine residue to L-isoleucine amide." [RESID:AA0090]
subset	PSI-MOD-slim
synonym	"(2S,3S)-2-amino-3-methylpentanamide" EXACT RESID-systematic []
synonym	"amidated L-isoleucine" EXACT PSI-MOD-alternate []
synonym	"IleN" EXACT PSI-MOD-label []
synonym	"isoleucinamide" EXACT RESID-alternate []
synonym	"L-isoleucine amide" EXACT RESID-name []
synonym	"MOD_RES Isoleucine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 6 H 13 N 2 O 1"
xref	MassAvg: "129.18"
xref	MassMono: "129.102788"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue

2.100. MOD:00100 L-leucine amide

Table 102. Term [MOD:00100]
id	MOD:00100
name	L-leucine amide
def	"A protein modification that effectively converts an L-leucine residue to L-leucine amide." [PubMed:2578459, RESID:AA0091]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-methylpentanamide" EXACT RESID-systematic []
synonym	"2-amino-4-methylvaleramide" EXACT RESID-alternate []
synonym	"2-azanyl-4-methylpentanamide" EXACT RESID-alternate []
synonym	"alpha-aminoisocaproamide" EXACT RESID-alternate []
synonym	"amidated L-leucine" EXACT PSI-MOD-alternate []
synonym	"L-leucine amide" EXACT RESID-name []
synonym	"leucinamide" EXACT RESID-alternate []
synonym	"LeuN" EXACT PSI-MOD-label []
synonym	"MOD_RES Leucine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 6 H 13 N 2 O 1"
xref	MassAvg: "129.18"
xref	MassMono: "129.102788"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.101. MOD:00101 L-lysine amide

Table 103. Term [MOD:00101]
id	MOD:00101
name	L-lysine amide
def	"A protein modification that effectively converts an L-lysine residue to L-lysine amide." [PubMed:6579533, RESID:AA0092]
subset	PSI-MOD-slim
synonym	"(2S)-2,6-diaminohexanamide" EXACT RESID-systematic []
synonym	"amidated L-lysine" EXACT PSI-MOD-alternate []
synonym	"L-lysine amide" EXACT RESID-name []
synonym	"lysinamide" EXACT RESID-alternate []
synonym	"LysN" EXACT PSI-MOD-label []
synonym	"MOD_RES Lysine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 6 H 14 N 3 O 1"
xref	MassAvg: "144.20"
xref	MassMono: "144.113687"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.102. MOD:00102 L-methionine amide

Table 104. Term [MOD:00102]
id	MOD:00102
name	L-methionine amide
def	"A protein modification that effectively converts an L-methionine residue to L-methionine amide." [PubMed:4375977, RESID:AA0093]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-(methylsulfanyl)butanamide" EXACT RESID-systematic []
synonym	"2-amino-4-(methylthio)butanamide" EXACT RESID-alternate []
synonym	"amidated L-methionine" EXACT PSI-MOD-alternate []
synonym	"L-methionine amide" EXACT RESID-name []
synonym	"methioninamide" EXACT RESID-alternate []
synonym	"MetN" EXACT PSI-MOD-label []
synonym	"MOD_RES Methionine amide" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1 S 0"
xref	DiffMono: "-0.984016"
xref	Formula: "C 5 H 11 N 2 O 1 S 1"
xref	MassAvg: "147.22"
xref	MassMono: "147.059209"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.103. MOD:00103 L-phenylalanine amide

Table 105. Term [MOD:00103]
id	MOD:00103
name	L-phenylalanine amide
def	"A protein modification that effectively converts an L-phenylalanine residue to L-phenylalanine amide." [PubMed:2905621, PubMed:8868490, RESID:AA0094]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-phenylpropanamide" EXACT RESID-systematic []
synonym	"amidated L-phenylalanine" EXACT PSI-MOD-alternate []
synonym	"L-phenylalanine amide" EXACT RESID-name []
synonym	"MOD_RES Phenylalanine amide" EXACT UniProt-feature []
synonym	"PheN" EXACT PSI-MOD-label []
synonym	"phenylalaninamide" EXACT RESID-alternate []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 9 H 11 N 2 O 1"
xref	MassAvg: "163.20"
xref	MassMono: "163.087138"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.104. MOD:00104 L-proline amide

Table 106. Term [MOD:00104]
id	MOD:00104
name	L-proline amide
def	"A protein modification that effectively converts an L-proline residue to L-proline amide." [PubMed:4982117, PubMed:5760861, RESID:AA0095]
subset	PSI-MOD-slim
synonym	"(2S)-pyrrolidine-2-carboxamide" EXACT RESID-systematic []
synonym	"amidated L-proline" EXACT PSI-MOD-alternate []
synonym	"L-proline amide" EXACT RESID-name []
synonym	"MOD_RES Proline amide" EXACT UniProt-feature []
synonym	"prolinamide" EXACT RESID-alternate []
synonym	"ProN" EXACT PSI-MOD-label []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 5 H 9 N 2 O 1"
xref	MassAvg: "113.14"
xref	MassMono: "113.071488"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.105. MOD:00105 L-serine amide

Table 107. Term [MOD:00105]
id	MOD:00105
name	L-serine amide
def	"A protein modification that effectively converts an L-serine residue to L-serine amide." [PubMed:743209, RESID:AA0096]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-hydroxypropanamide" EXACT RESID-systematic []
synonym	"amidated L-serine" EXACT PSI-MOD-alternate []
synonym	"L-serine amide" EXACT RESID-name []
synonym	"MOD_RES Serine amide" EXACT UniProt-feature []
synonym	"serinamide" EXACT RESID-alternate []
synonym	"SerN" EXACT PSI-MOD-label []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 3 H 7 N 2 O 2"
xref	MassAvg: "103.10"
xref	MassMono: "103.050752"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.106. MOD:00106 L-threonine amide

Table 108. Term [MOD:00106]
id	MOD:00106
name	L-threonine amide
def	"A protein modification that effectively converts an L-threonine residue to L-threonine amide." [PubMed:1390774, RESID:AA0097]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-hydroxybutanamide" EXACT RESID-systematic []
synonym	"amidated L-threonine" EXACT PSI-MOD-alternate []
synonym	"L-threonine amide" EXACT RESID-name []
synonym	"MOD_RES Threonine amide" EXACT UniProt-feature []
synonym	"threoninamide" EXACT RESID-alternate []
synonym	"ThrN" EXACT PSI-MOD-label []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 4 H 9 N 2 O 2"
xref	MassAvg: "117.13"
xref	MassMono: "117.066403"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.107. MOD:00107 L-tryptophan amide

Table 109. Term [MOD:00107]
id	MOD:00107
name	L-tryptophan amide
def	"A protein modification that effectively converts an L-tryptophan residue to L-tryptophan amide." [PubMed:3947348, RESID:AA0098]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1H-indol-3-yl)propanamide" EXACT RESID-systematic []
synonym	"amidated L-tryptophan" EXACT PSI-MOD-alternate []
synonym	"L-tryptophan amide" EXACT RESID-name []
synonym	"MOD_RES Tryptophan amide" EXACT UniProt-feature []
synonym	"TrpN" EXACT PSI-MOD-label []
synonym	"tryptophanamide" EXACT RESID-alternate []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 11 H 12 N 3 O 1"
xref	MassAvg: "202.24"
xref	MassMono: "202.098037"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.108. MOD:00108 L-tyrosine amide

Table 110. Term [MOD:00108]
id	MOD:00108
name	L-tyrosine amide
def	"A protein modification that effectively converts an L-tyrosine residue to L-tyrosine amide." [PubMed:1377792, PubMed:3562898, PubMed:6509012, RESID:AA0099]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-hydoxyphenyl)propanamide" EXACT RESID-systematic []
synonym	"amidated L-tyrosine" EXACT PSI-MOD-alternate []
synonym	"L-tyrosine amide" EXACT RESID-name []
synonym	"MOD_RES Tyrosine amide" EXACT UniProt-feature []
synonym	"TyrN" EXACT PSI-MOD-label []
synonym	"tyrosinamide" EXACT RESID-alternate []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 9 H 11 N 2 O 2"
xref	MassAvg: "179.20"
xref	MassMono: "179.082053"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.109. MOD:00109 L-valine amide

Table 111. Term [MOD:00109]
id	MOD:00109
name	L-valine amide
def	"A protein modification that effectively converts an L-valine residue to L-valine amide." [PubMed:2578459, PubMed:5465996, RESID:AA0100]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-methylbutanamide" EXACT RESID-systematic []
synonym	"L-valine amide" EXACT RESID-name []
synonym	"MOD_RES Valine amide" EXACT UniProt-feature []
synonym	"valinamide" EXACT RESID-alternate []
synonym	"ValN" EXACT PSI-MOD-label []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 5 H 11 N 2 O 1"
xref	MassAvg: "115.16"
xref	MassMono: "115.087138"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00883 C1-amidated residue ! C1-amidated residue
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue

2.110. MOD:00110 L-cysteine methyl disulfide

Table 112. Term [MOD:00110]
id	MOD:00110
name	L-cysteine methyl disulfide
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl disulfide." [OMSSA:179, PubMed:10555576, PubMed:163643, PubMed:2056535, PubMed:6381494, RESID:AA0101, UniMod:39#C]
comment	Produced artifactually by reaction of cysteine residues with methyl methanethiosulfonate (MMTS) [JSG].
synonym	"(2R)-2-amino-3-(methyldisulfanediyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(methyldisulfanediyl)propanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-(methyldithio)propanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-methyldisulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-(methyldisulfanediyl)-propanoic acid" EXACT RESID-alternate []
synonym	"Beta-methylthiolation" RELATED UniMod-description []
synonym	"L-3-(methyldithio)alanine" EXACT RESID-alternate []
synonym	"L-cysteine methyl disulfide" EXACT RESID-name []
synonym	"methyl methanethiolsulfonate derivatized cysteine" EXACT PSI-MOD-alternate []
synonym	"methyl methanethiosulfonate derivatized cysteine" EXACT PSI-MOD-alternate []
synonym	"Methylthio" RELATED PSI-MS-label []
synonym	"Methylthio" RELATED UniMod-interim []
synonym	"mmts" EXACT OMSSA-label []
synonym	"MOD_RES Cysteine methyl disulfide" EXACT UniProt-feature []
synonym	"S-methylthio-L-cysteine" EXACT RESID-alternate []
synonym	"S-methylthiocysteine" EXACT RESID-alternate []
xref	DiffAvg: "46.09"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 1"
xref	DiffMono: "45.987721"
xref	Formula: "C 4 H 7 N 1 O 1 S 2"
xref	MassAvg: "149.23"
xref	MassMono: "148.996906"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01153 methylthiolated residue ! methylthiolated residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.111. MOD:00111 S-farnesyl-L-cysteine

Table 113. Term [MOD:00111]
id	MOD:00111
name	S-farnesyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine." [DeltaMass:293, OMSSA:42, PubMed:1409665, PubMed:15609361, PubMed:1872463, PubMed:2684976, RESID:AA0102, UniMod:44#C]
comment	From DeltaMass: (name misspelled "S-farnesyl cystenyl")
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-([(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(3,7,11-trimethyl-2,6,10-dodecatrienylthio)propanoic acid" EXACT RESID-alternate []
synonym	"Farnesyl" RELATED PSI-MS-label []
synonym	"Farnesylation" RELATED UniMod-description []
synonym	"farnesylationc" EXACT OMSSA-label []
synonym	"LIPID S-farnesyl cysteine" EXACT UniProt-feature []
synonym	"S-farnesyl Cystenyl" EXACT DeltaMass-label []
synonym	"S-farnesyl-L-cysteine" EXACT RESID-name []
synonym	"SFarnCys" EXACT PSI-MOD-label []
xref	DiffAvg: "204.36"
xref	DiffFormula: "C 15 H 24 N 0 O 0 S 0"
xref	DiffMono: "204.187801"
xref	Formula: "C 18 H 29 N 1 O 1 S 1"
xref	MassAvg: "307.50"
xref	MassMono: "307.196986"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00437 farnesylated residue ! farnesylated residue
is_a	MOD:01110 isoprenylated cysteine ! isoprenylated cysteine

2.112. MOD:00112 S-12-hydroxyfarnesyl-L-cysteine

Table 114. Term [MOD:00112]
id	MOD:00112
name	S-12-hydroxyfarnesyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-12-hydroxyfarnesyl-L-cysteine." [PubMed:17790543, RESID:AA0103, UniMod:376]
synonym	"(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(12-hydroxy-3,7,11-trimethyl-3,6,10-dodecatrienylthio)propanoic acid" EXACT RESID-alternate []
synonym	"Hydroxyfarnesyl" RELATED PSI-MS-label []
synonym	"hydroxyfarnesyl" RELATED UniMod-description []
synonym	"LIPID S-12-hydroxyfarnesyl cysteine" EXACT UniProt-feature []
synonym	"S-12-hydroxyfarnesyl-L-cysteine" EXACT RESID-name []
synonym	"S12HyFarnCys" EXACT PSI-MOD-label []
xref	DiffAvg: "220.36"
xref	DiffFormula: "C 15 H 24 N 0 O 1 S 0"
xref	DiffMono: "220.182715"
xref	Formula: "C 18 H 29 N 1 O 2 S 1"
xref	MassAvg: "323.50"
xref	MassMono: "323.191900"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01110 isoprenylated cysteine ! isoprenylated cysteine

2.113. MOD:00113 S-geranylgeranyl-L-cysteine

Table 115. Term [MOD:00113]
id	MOD:00113
name	S-geranylgeranyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine." [DeltaMass:0, OMSSA:49, PubMed:1483450, PubMed:15609361, RESID:AA0104, UniMod:48#C]
comment	DeltaMass calculates the mass with two double bonds rather than four
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenylthio)propanoic acid" EXACT RESID-alternate []
synonym	"Geranyl-geranyl" RELATED UniMod-description []
synonym	"GeranylGeranyl" RELATED PSI-MS-label []
synonym	"geranylgeranylc" EXACT OMSSA-label []
synonym	"LIPID S-geranylgeranyl cysteine" EXACT UniProt-feature []
synonym	"S-geranylgeranyl" EXACT DeltaMass-label []
synonym	"S-geranylgeranyl-L-cysteine" EXACT RESID-name []
synonym	"SGergerCys" EXACT PSI-MOD-label []
xref	DiffAvg: "272.48"
xref	DiffFormula: "C 20 H 32 N 0 O 0 S 0"
xref	DiffMono: "272.250401"
xref	Formula: "C 23 H 37 N 1 O 1 S 1"
xref	MassAvg: "375.62"
xref	MassMono: "375.259586"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00441 geranylgeranylated residue ! geranylgeranylated residue
is_a	MOD:01110 isoprenylated cysteine ! isoprenylated cysteine

2.114. MOD:00114 L-cysteine methyl ester

Table 116. Term [MOD:00114]
id	MOD:00114
name	L-cysteine methyl ester
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl ester." [PubMed:11875433, PubMed:1872463, RESID:AA0105, UniMod:34#C-term]
comment	Secondary to RESID:AA0102; secondary to RESID:AA0103; secondary to RESID:AA0104.
subset	PSI-MOD-slim
synonym	"2-amino-3-mercaptopropanoic methyl ester" EXACT RESID-alternate []
synonym	"2-amino-3-sulfanylpropanoic methyl ester" EXACT RESID-alternate []
synonym	"L-cysteine methyl ester" EXACT RESID-name []
synonym	"mecysteine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methyl (2R)-2-amino-3-sulfanylpropanoate" EXACT RESID-systematic []
synonym	"methyl esterified L-cysteine" EXACT PSI-MOD-alternate []
synonym	"methyl L-cysteinate" EXACT RESID-alternate []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Cysteine methyl ester" EXACT UniProt-feature []
synonym	"OMeCys" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 4 H 8 N 1 O 2 S 1"
xref	MassAvg: "134.17"
xref	MassMono: "134.027574"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01682 monomethylated L-cysteine ! monomethylated L-cysteine
is_a	MOD:01689 alpha-carboxyl methylated residue ! alpha-carboxyl methylated residue

2.115. MOD:00115 S-palmitoyl-L-cysteine

Table 117. Term [MOD:00115]
id	MOD:00115
name	S-palmitoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine." [DeltaMass:303, PubMed:1872406, PubMed:3166978, PubMed:8180229, PubMed:8824274, RESID:AA0106, UniMod:47#C]
comment	From DeltaMass: (name misspelled "S-palmityl Cystenyl" and formula incorrect, N and O reversed) Formula: C19H35O1N2S1 Monoisotopic Mass Change: 341.239 Average Mass Change: 341.556
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-(hexadecanoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(hexadecanoylthio)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE S-palmitoyl cysteine intermediate" EXACT UniProt-feature []
synonym	"cysteine hexadecanoate thioester" EXACT RESID-alternate []
synonym	"cysteine palmitate thioester" EXACT RESID-alternate []
synonym	"LIPID S-palmitoyl cysteine" EXACT UniProt-feature []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"S-palmitoyl-L-cysteine" EXACT RESID-name []
synonym	"S-palmitoylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-palmityl Cystenyl" EXACT DeltaMass-label []
synonym	"SPamCys" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "C 19 H 35 N 1 O 2 S 1"
xref	MassAvg: "341.55"
xref	MassMono: "341.238850"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00653 S-palmitoylated residue ! S-palmitoylated residue
is_a	MOD:01684 palmitoylated-L-cysteine ! palmitoylated-L-cysteine

2.116. MOD:00116 S-diacylglycerol-L-cysteine

Table 118. Term [MOD:00116]
id	MOD:00116
name	S-diacylglycerol-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-diacylglycerol-L-cysteine." [PubMed:10896212, PubMed:4575979, PubMed:9056182, RESID:AA0107, UniMod:377#C]
comment	Incidental to RESID:AA0060.
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-[(2S)-2-((9Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]thiopropanoic acid" EXACT RESID-alternate []
synonym	"Diacylglycerol" RELATED PSI-MS-label []
synonym	"diacylglycerol" RELATED UniMod-description []
synonym	"LIPID S-diacylglycerol cysteine" EXACT UniProt-feature []
synonym	"S-(1-2'-oleoyl-3'-palmitoyl-glycerol)cysteine" EXACT RESID-alternate []
synonym	"S-(2',3'-diacylglycerol)-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-diacylglycerol-L-cysteine" EXACT RESID-name []
synonym	"SAcyl2GlyceroCys" EXACT PSI-MOD-label []
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.117. MOD:00117 S-(L-isoglutamyl)-L-cysteine

Table 119. Term [MOD:00117]
id	MOD:00117
name	S-(L-isoglutamyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-glutamine residue by a thioester bond with the formation of S-(L-isoglutamyl)-L-cysteine and the release of ammonia." [ChEBI:22021, DeltaMass:0, PubMed:6838833, RESID:AA0108]
comment	Cross-link 2; DeltaMass calculates the mass difference from glutamic acid rather than glutamine.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(S,R)-2-amino-4-[S-(2-amino-2-carboxyethyl)thiocarboxy]butanoic acid" EXACT RESID-alternate []
synonym	"2-amino-5-(2-amino-2-carboxyethyl)thio-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoglutamyl cysteine thioester (Cys-Gln)" EXACT UniProt-feature []
synonym	"gamma-(S-cysteinyl)glutamic acid" EXACT RESID-alternate []
synonym	"S-(L-isoglutamyl)-L-cysteine" EXACT RESID-name []
synonym	"S-gamma-glutamyl (crosslinked to cysteine)" EXACT DeltaMass-label []
synonym	"XLNK-SCys-5Glu(Gln)" EXACT PSI-MOD-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0 S 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 8 H 10 N 2 O 3 S 1"
xref	MassAvg: "214.24"
xref	MassMono: "214.041213"
xref	Origin: "C, Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia

2.118. MOD:00118 2'-(S-L-cysteinyl)-L-histidine

Table 120. Term [MOD:00118]
id	MOD:00118
name	2'-(S-L-cysteinyl)-L-histidine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-histidine residue by a thioether bond to form 2'-(S-L-cysteinyl)-L-histidine." [DeltaMass:0, PubMed:6210696, RESID:AA0109]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-[(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)sulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-amino-3-[2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-1H-imidazol-4-yl]propanoic acid" EXACT RESID-alternate []
synonym	"2'-(L-cystein-S-yl)-L-histidine" EXACT RESID-name []
synonym	"CROSSLNK 2'-(S-cysteinyl)-histidine (Cys-His)" EXACT UniProt-feature []
synonym	"S-(2'-histidyl)cysteine" EXACT RESID-alternate []
synonym	"S-(2-histidyl)- (crosslinked to cysteine)" EXACT DeltaMass-label []
synonym	"XLNK-SCys-2’His" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 9 H 10 N 4 O 2 S 1"
xref	MassAvg: "238.26"
xref	MassMono: "238.052447"
xref	Origin: "C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.119. MOD:00119 L-lanthionine (Cys-Ser)

Table 121. Term [MOD:00119]
id	MOD:00119
name	L-lanthionine (Cys-Ser)
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form L-lanthionine." [ChEBI:21347, DeltaMass:7, RESID:AA0110#CSX]
comment	Cross-link 2. The natural occurrence of this modification is rare. For the more common modification see MOD:00120 meso-lanthionine [JSG].
synonym	"(2R,2’R)-3,3'-sulfanediylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"®-S-(2-amino-2-carboxyethyl)-L-cysteine" EXACT RESID-alternate []
synonym	"(R,R)-2,6-diamino-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(R,R)-3,3'-thiobis-(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"(R,R)-bis(2-amino-2-carboxyethyl)sulfide" EXACT RESID-alternate []
synonym	"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"3,3'-thiobis-L-alanine" EXACT RESID-alternate []
synonym	"L-lanthionine" EXACT RESID-name []
synonym	"XLNK-SCys-(L)3Dha" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01839 L-lanthionine ! L-lanthionine

2.120. MOD:00120 meso-lanthionine

Table 122. Term [MOD:00120]
id	MOD:00120
name	meso-lanthionine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form meso-lanthionine." [PubMed:15023056, PubMed:3769923, RESID:AA0111]
comment	Cross-link 2.
synonym	"(2R,2’S)-3,3'-sulfanediylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"(2R,2’S)-3,3'-thiobis-(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"(2R,6S)-2,6-diamino-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(2R,6S)-meso-lanthionine" EXACT RESID-alternate []
synonym	"(2S)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanyl]propanoic acid" EXACT RESID-alternate []
synonym	"(2S,6R)-meso-lanthionine" RELATED RESID-misnomer []
synonym	"®-S-(2-amino-2-carboxyethyl)-D-cysteine" EXACT RESID-alternate []
synonym	"(R,S)-bis(2-amino-2-carboxyethyl)sulfide" EXACT RESID-alternate []
synonym	"3,3'-thiobis-meso-alanine" EXACT RESID-alternate []
synonym	"CROSSLNK Lanthionine (Cys-Ser)" EXACT UniProt-feature []
synonym	"CROSSLNK Lanthionine (Ser-Cys)" EXACT UniProt-feature []
synonym	"cysteine-3-D-alanine thioether" EXACT RESID-alternate []
synonym	"meso-lanthionine" EXACT RESID-name []
synonym	"XLNK-SCys-(D)3Dha" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01841 lanthionine ! lanthionine

2.121. MOD:00121 (2S,3S,2’R)-3-methyllanthionine

Table 123. Term [MOD:00121]
id	MOD:00121
name	(2S,3S,2’R)-3-methyllanthionine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form (2S,3S,2’R)-3-methyllanthionine." [PubMed:3769923, RESID:AA0112]
comment	Cross-link 2.
synonym	"(2S,3S)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"(2S,3S,2’R)-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid" EXACT RESID-alternate []
synonym	"(2S,3S,2’R)-3-methyllanthionine" EXACT RESID-name []
synonym	"(2S,3S,6R)-2,6-diamino-3-methyl-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(2S,3S,6R)-3-methyllanthionine" EXACT RESID-alternate []
synonym	"(2S-[2R,3R(S*)])-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid" EXACT RESID-alternate []
synonym	"3-methyl-D,L-lanthionine" EXACT RESID-alternate []
synonym	"CROSSLNK Beta-methyllanthionine (Cys-Thr)" EXACT UniProt-feature []
synonym	"CROSSLNK Beta-methyllanthionine (Thr-Cys)" EXACT UniProt-feature []
synonym	"cysteine-3-D-butyrine thioether" EXACT RESID-alternate []
synonym	"XLNK-SCys-3Dhb" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 10 N 2 O 2 S 1"
xref	MassAvg: "186.23"
xref	MassMono: "186.046299"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01981 3-methyllanthionine ! 3-methyllanthionine

2.122. MOD:00122 3'-(S-L-cysteinyl)-L-tyrosine

Table 124. Term [MOD:00122]
id	MOD:00122
name	3'-(S-L-cysteinyl)-L-tyrosine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-tyrosine." [DeltaMass:0, PubMed:15917234, PubMed:2002850, RESID:AA0113]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-(3-[(2R)2-amino-2-carboxyethylsulfanyl]-4-hydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-[3-(2-amino-2-carboxyethylthio)-4-hydroxyphenyl]propanoic acid" EXACT RESID-alternate []
synonym	"3'-(cystein-S-yl)tyrosine" EXACT RESID-alternate []
synonym	"3'-(L-cystein-S-yl)-L-tyrosine" EXACT RESID-name []
synonym	"CROSSLNK 3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" EXACT UniProt-feature []
synonym	"CROSSLNK 3'-(S-cysteinyl)-tyrosine (Tyr-Cys)" EXACT UniProt-feature []
synonym	"S-(3-Tyr) (Crosslinked to Cysteine)" EXACT DeltaMass-label []
synonym	"S-(tyros-3'-yl)cysteine" EXACT RESID-alternate []
synonym	"XLNK-SCys-3’Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 3 S 1"
xref	MassAvg: "264.30"
xref	MassMono: "264.056863"
xref	Origin: "C, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.123. MOD:00123 N6-carboxy-L-lysine

Table 125. Term [MOD:00123]
id	MOD:00123
name	N6-carboxy-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-carboxy-L-lysine." [PubMed:11369851, PubMed:4436319, PubMed:637859, PubMed:7754395, RESID:AA0114, UniMod:299#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(carboxyamino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-6-carbamic hexanoic acid" EXACT RESID-alternate []
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxylation" RELATED UniMod-description []
synonym	"lysine NZ-carboxylic acid" EXACT RESID-alternate []
synonym	"MOD_RES N6-carboxylysine" EXACT UniProt-feature []
synonym	"N6-carbamyllysine" RELATED RESID-misnomer []
synonym	"N6-carboxy-L-lysine" EXACT RESID-name []
synonym	"N6-carboxylysine" EXACT RESID-alternate []
synonym	"N6CbxLys" EXACT PSI-MOD-label []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 7 H 12 N 2 O 3"
xref	MassAvg: "172.18"
xref	MassMono: "172.084792"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.124. MOD:00124 N6-1-carboxyethyl-L-lysine

Table 126. Term [MOD:00124]
id	MOD:00124
name	N6-1-carboxyethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-1-carboxyethyl-L-lysine." [PubMed:3123486, PubMed:8253186, PubMed:8421682, RESID:AA0115, UniMod:378#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-([(1S)-1-carboxyethyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"Carboxyethyl" RELATED PSI-MS-label []
synonym	"carboxyethyl" RELATED UniMod-description []
synonym	"MOD_RES N6-1-carboxyethyl lysine" EXACT UniProt-feature []
synonym	"N6-(1-carboxyethyl)-L-lysine" EXACT RESID-name []
synonym	"N6-(1-carboxyethyl)lysine" EXACT RESID-alternate []
synonym	"N6CbzEtLys" EXACT PSI-MOD-label []
synonym	"NZ-(1-carboxyethyl)lysine" EXACT RESID-alternate []
xref	DiffAvg: "72.06"
xref	DiffFormula: "C 3 H 4 N 0 O 2"
xref	DiffMono: "72.021129"
xref	Formula: "C 9 H 16 N 2 O 3"
xref	MassAvg: "200.24"
xref	MassMono: "200.116092"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.125. MOD:00125 hypusine

Table 127. Term [MOD:00125]
id	MOD:00125
name	hypusine
def	"A protein modification that effectively converts an L-lysine residue to hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine." [DeltaMass:0, PubMed:6806267, PubMed:8108861, RESID:AA0116, UniMod:379#K]
comment	This modification occurs uniquely in translation initiation factor eIF-5A [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-([(2R)-4-amino-2-hydroxybutyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"(2S,9R)-2,11-diazanyl-9-hydroxy-7-azaundecanoic acid" EXACT RESID-alternate []
synonym	"(2S,9R)-hypusine" EXACT RESID-alternate []
synonym	"2-azanyl-6-[(4-azanyl-2-hydroxybutyl)azanyl]hexanoic acid" EXACT RESID-alternate []
synonym	"Hypu" EXACT PSI-MOD-label []
synonym	"Hypusine" RELATED PSI-MS-label []
synonym	"hypusine" RELATED UniMod-description []
synonym	"L-hypusine" EXACT RESID-name []
synonym	"MOD_RES Hypusine" EXACT UniProt-feature []
synonym	"N-(4-NH2-2-OH-butyl)- (of Lysine)" EXACT DeltaMass-label []
synonym	"N6-(4-amino-2-hydroxybutyl)-L-lysine" EXACT RESID-alternate []
xref	DiffAvg: "87.12"
xref	DiffFormula: "C 4 H 9 N 1 O 1"
xref	DiffMono: "87.068414"
xref	Formula: "C 10 H 21 N 3 O 2"
xref	MassAvg: "215.30"
xref	MassMono: "215.163377"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01884 4-aminobutylated residue ! 4-aminobutylated residue
relationship	derives_from MOD:01880 L-deoxyhypusine ! L-deoxyhypusine

2.126. MOD:00126 N6-biotinyl-L-lysine

Table 128. Term [MOD:00126]
id	MOD:00126
name	N6-biotinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-biotinyl-L-lysine." [DeltaMass:305, PubMed:16109483, PubMed:3178228, PubMed:7948875, PubMed:8747466, RESID:AA0117, UniMod:3#K]
comment	From DeltaMass: Average Mass: 354 Formula:C 16 H 26 O 4 N 3 S 1 (formula incorrect, N and O reversed) Monoisotopic Mass Change:354.172 Average Mass Change:354.471 References:PE Sciex.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"(3aS-(3aalpha,4beta,6aalpha))-N6-(5-(hexahydro-2-oxo-1H-thieno(3,4-d)imidazol-4-yl)-1-oxopentyl)-L-lysine" EXACT RESID-alternate []
synonym	"biocytin" EXACT RESID-alternate []
synonym	"Biotin" RELATED PSI-MS-label []
synonym	"biotinyl lysyl" EXACT DeltaMass-label []
synonym	"Biotinylation" RELATED UniMod-description []
synonym	"epsilon-N-biotinyllysine" EXACT RESID-alternate []
synonym	"MOD_RES N6-biotinyllysine" EXACT UniProt-feature []
synonym	"N6-[5-((3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]-L-lysine" EXACT RESID-alternate []
synonym	"N6-biotinyl-L-lysine" EXACT RESID-name []
synonym	"N6-biotinyllysine" EXACT RESID-alternate []
synonym	"N6BtnLys" EXACT PSI-MOD-label []
xref	DiffAvg: "226.29"
xref	DiffFormula: "C 10 H 14 N 2 O 2 S 1"
xref	DiffMono: "226.077599"
xref	Formula: "C 16 H 26 N 4 O 3 S 1"
xref	MassAvg: "354.47"
xref	MassMono: "354.172562"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
is_a	MOD:01885 biotinylated residue ! biotinylated residue

2.127. MOD:00127 N6-lipoyl-L-lysine

Table 129. Term [MOD:00127]
id	MOD:00127
name	N6-lipoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-lipoyl-L-lysine." [DeltaMass:0, OMSSA:67, PubMed:3421911, PubMed:3522581, PubMed:7719855, RESID:AA0118, UniMod:42#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(5-[(3R)-1,2-dithiolan-3-yl]pentanamido)hexanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-6-[(5-[(3R)-1,2-dithiolan-3-yl]pentanoyl)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"(2S,6’R)-2-amino-6-(6,8-dithiooctanamido)hexanoic acid" EXACT RESID-alternate []
synonym	"2-amino-6-(5-[1,2-dithiolan-3-yl]-1-oxopentyl)aminohexanoic acid" EXACT RESID-alternate []
synonym	"Lipoyl" RELATED PSI-MS-label []
synonym	"Lipoyl" RELATED UniMod-description []
synonym	"lipoylk" EXACT OMSSA-label []
synonym	"MOD_RES N6-lipoyllysine" EXACT UniProt-feature []
synonym	"N-Lipoyl- (on Lysine)" EXACT DeltaMass-label []
synonym	"N6-6,8-dithiooctanoyllysine" EXACT RESID-alternate []
synonym	"N6-lipoyl-L-lysine" EXACT RESID-name []
synonym	"N6-lipoyllysine" EXACT RESID-alternate []
synonym	"N6LipLys" EXACT PSI-MOD-label []
xref	DiffAvg: "188.30"
xref	DiffFormula: "C 8 H 12 N 0 O 1 S 2"
xref	DiffMono: "188.032957"
xref	Formula: "C 14 H 24 N 2 O 2 S 2"
xref	MassAvg: "316.48"
xref	MassMono: "316.127920"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.128. MOD:00128 N6-pyridoxal phosphate-L-lysine

Table 130. Term [MOD:00128]
id	MOD:00128
name	N6-pyridoxal phosphate-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine." [DeltaMass:0, PubMed:1544460, RESID:AA0119, UniMod:46#K]
comment	From DeltaMass: Average Mass: 231
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-[([3-hydroxy-2-methyl-5-phosphonooxymethylpyridin-4-yl]methylidene)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N6-(pyridoxal phosphate)lysine" EXACT UniProt-feature []
synonym	"N6-pyridoxal phosphate-L-lysine" EXACT RESID-name []
synonym	"N6PydoxLys" EXACT PSI-MOD-label []
synonym	"Pyridoxal phosphate" RELATED UniMod-description []
synonym	"Pyridoxal phosphate (Schiff Base formed to lysine)" EXACT DeltaMass-label []
synonym	"PyridoxalPhosphate" RELATED PSI-MS-label []
xref	DiffAvg: "229.13"
xref	DiffFormula: "C 8 H 8 N 1 O 5 P 1"
xref	DiffMono: "229.014009"
xref	Formula: "C 14 H 20 N 3 O 6 P 1"
xref	MassAvg: "357.30"
xref	MassMono: "357.108972"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.129. MOD:00129 N6-retinylidene-L-lysine

Table 131. Term [MOD:00129]
id	MOD:00129
name	N6-retinylidene-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-retinylidene-L-lysine, the adduct of retinal." [PubMed:6794028, PubMed:6870827, RESID:AA0120, UniMod:380#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)-2,4,6,8-nonatetraenylidene]aminohexanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N6-(retinylidene)lysine" EXACT UniProt-feature []
synonym	"N6-retinal-L-lysine" EXACT RESID-alternate []
synonym	"N6-retinyl-lysine" EXACT RESID-alternate []
synonym	"N6-retinylidene-L-lysine" EXACT RESID-name []
synonym	"N6RetalLys" EXACT PSI-MOD-label []
synonym	"retinal" RELATED UniMod-description []
synonym	"Retinylidene" RELATED PSI-MS-label []
xref	DiffAvg: "266.43"
xref	DiffFormula: "C 20 H 26 N 0 O 0"
xref	DiffMono: "266.203451"
xref	Formula: "C 26 H 38 N 2 O 1"
xref	MassAvg: "394.60"
xref	MassMono: "394.298414"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.130. MOD:00130 L-allysine

Table 132. Term [MOD:00130]
id	MOD:00130
name	L-allysine
def	"A protein modification that effectively converts an L-lysine residue to L-allysine." [ChEBI:17917, DeltaMass:0, PubMed:11120890, PubMed:11332453, PubMed:358196, PubMed:5337886, PubMed:5529814, RESID:AA0121, UniMod:352#K]
comment	From DeltaMass: Average Mass: -1
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-oxohexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-formylvaleric acid" EXACT RESID-alternate []
synonym	"2-amino-adipic acid semialdahyde" EXACT RESID-alternate []
synonym	"2-aminoadipate 6-semialdehyde" EXACT RESID-alternate []
synonym	"5-formyl-norvaline" EXACT RESID-alternate []
synonym	"6-oxonorleucine" EXACT RESID-alternate []
synonym	"AASA" EXACT RESID-alternate []
synonym	"Allysine (from Lysine)" EXACT DeltaMass-label []
synonym	"alpha-amino-adipic acid delta-semialdahyde" EXACT RESID-alternate []
synonym	"L-allysine" EXACT RESID-name []
synonym	"Lys→Allysine" RELATED PSI-MS-label []
synonym	"Lysal" EXACT PSI-MOD-label []
synonym	"Lysine oxidation to aminoadipic semialdehyde" RELATED UniMod-description []
synonym	"MOD_RES Allysine" EXACT UniProt-feature []
synonym	"Oxidation of lysine (to aminoadipic semialdehyde)" EXACT DeltaMass-label []
xref	DiffAvg: "-1.03"
xref	DiffFormula: "C 0 H -3 N -1 O 1"
xref	DiffMono: "-1.031634"
xref	Formula: "C 6 H 9 N 1 O 2"
xref	MassAvg: "127.14"
xref	MassMono: "127.063329"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.131. MOD:00131 L-2-aminoadipic acid

Table 133. Term [MOD:00131]
id	MOD:00131
name	L-2-aminoadipic acid
def	"A protein modification that effectively converts an L-lysine residue to L-2-aminoadipic acid." [DeltaMass:353, PubMed:336041, PubMed:358196, PubMed:7419498, RESID:AA0122, UniMod:381#K]
comment	From DeltaMass: References:Amici A, Levine, RL, Tsai, L, and Stadtman, ER: Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions. Journal of Biological Chemistry 264: 3341-3346 1989.Requena JR, Chao CC, Levine RL, and Stadtman ER: Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins. Proceedings of the National Academy of Sciences USA 98: 69-74 2001. Notes:Expected reaction following oxidation of lysine to aminoadipic semialdehyde. Not proven experimentally but deduced by reference to the similar known reaction of oxidation of Arg to Glu via the semialdehyde. [This has been observed as a natural modification, see RESID:AA0122. JSG]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminohexanedioic acid" EXACT RESID-systematic []
synonym	"2-amino-1,4-butanedicarboxylic acid" EXACT RESID-alternate []
synonym	"alpha-amino adipic acid" RELATED UniMod-description []
synonym	"L-2-aminoadipic acid" EXACT RESID-name []
synonym	"L-alpha-aminoadipic acid" EXACT RESID-alternate []
synonym	"Lys→AminoadipicAcid" RELATED PSI-MS-label []
synonym	"Lysoic" EXACT PSI-MOD-label []
synonym	"Oxidation of lysine (to aminoadipic acid)" EXACT DeltaMass-label []
xref	DiffAvg: "14.97"
xref	DiffFormula: "C 0 H -3 N -1 O 2"
xref	DiffMono: "14.963280"
xref	Formula: "C 6 H 9 N 1 O 3"
xref	MassAvg: "143.14"
xref	MassMono: "143.058243"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.132. MOD:00132 L-lysinoalanine (Lys-Ser)

Table 134. Term [MOD:00132]
id	MOD:00132
name	L-lysinoalanine (Lys-Ser)
def	"A protein modification that effectively crosslinks an L-serine residue and an L-lysine residue to release water and form 2-amino-6-(2-amino-2-carboxyethylamino)hexanoic acid." [DeltaMass:0, PubMed:2544544, RESID:AA0123#KSX]
comment	Cross-link 2. This entry is for the crosslink of peptidyl serine and peptidyl lysine. For the modification of peptidyl lysine by a free serine see MOD:01838. From DeltaMass: Average Mass: -34.
synonym	"(2R,9S)-lysinoalanine" EXACT RESID-alternate []
synonym	"(2S)-2-amino-6-([(2R)-2-amino-2-carboxyethyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"alaninolysine" EXACT RESID-alternate []
synonym	"CROSSLNK Lysinoalanine (Ser-Lys)" EXACT UniProt-feature []
synonym	"L-lysinoalanine" EXACT RESID-name []
synonym	"LAL" EXACT RESID-alternate []
synonym	"Lysinoalanine (from Cysteine)" EXACT DeltaMass-label []
synonym	"N-epsilon-(2-amino-2-carboxyethyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-(2-amino-2-carboxyethyl)-L-lysine" EXACT RESID-alternate []
synonym	"XLNK-N6Lys-3Dha(Ser)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 9 H 15 N 3 O 2"
xref	MassAvg: "197.24"
xref	MassMono: "197.116427"
xref	Origin: "K, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01853 L-lysinoalanine ! L-lysinoalanine

2.133. MOD:00133 N6-(L-isoglutamyl)-L-lysine (Gln)

Table 135. Term [MOD:00133]
id	MOD:00133
name	N6-(L-isoglutamyl)-L-lysine (Gln)
def	"A protein modification that effectively crosslinks an L-glutamine residue and an L-lysine residue by an isopeptide bond with the formation of N6-(L-isoglutamyl)-L-lysine and the release of ammonia." [ChEBI:21863, DeltaMass:0, PubMed:2461365, PubMed:5637041, PubMed:5656070, PubMed:8598899, RESID:AA0124#GLN]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acid" EXACT RESID-alternate []
synonym	"5-glutamyl N6-lysine" EXACT RESID-alternate []
synonym	"CROSSLNK Isoglutamyl lysine isopeptide (Lys-Gln)" EXACT UniProt-feature []
synonym	"N alpha -(gamma-Glutamyl)-lysine" EXACT DeltaMass-label []
synonym	"N(epsilon)-(gamma-glutamyl)lysine" EXACT RESID-alternate []
synonym	"N6-(L-isoglutamyl)-L-lysine" EXACT RESID-name []
synonym	"XLNK-N6Lys-5Glu(Gln)" EXACT PSI-MOD-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 11 H 17 N 3 O 3"
xref	MassAvg: "239.27"
xref	MassMono: "239.126991"
xref	Origin: "K, Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia
is_a	MOD:01630 N6-(L-isoglutamyl)-L-lysine ! N6-(L-isoglutamyl)-L-lysine

2.134. MOD:00134 N6-glycyl-L-lysine

Table 136. Term [MOD:00134]
id	MOD:00134
name	N6-glycyl-L-lysine
def	"A protein modification that effectively crosslinks an L-lysine residue and a glycine residue by an isopeptide bond to form N6-glycyl-L-lysine." [ChEBI:21885, RESID:AA0125]
comment	Cross-link 2; this is the common crosslink structure formed by ubiquitin, SUMO, and similar proteins.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-[(aminoacetyl)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"N6-(glycyl)-L-lysine" EXACT RESID-name []
synonym	"N6-glycyllysine" EXACT RESID-alternate []
synonym	"XLNK-N6Lys-1Gly" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 8 H 14 N 3 O 2"
xref	MassAvg: "184.22"
xref	MassMono: "184.108602"
xref	Origin: "G, K"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.135. MOD:00135 N-(L-isoaspartyl)-glycine (Asn)

Table 137. Term [MOD:00135]
id	MOD:00135
name	N-(L-isoaspartyl)-glycine (Asn)
def	"A protein modification that effectively crosslinks an L-asparagine residue and a glycine residue by an isopeptide bond with formation of N-(L-isoaspartyl)glycine and the release of ammonia." [ChEBI:21479, PubMed:1826288, RESID:AA0126]
comment	Cross-link 2.
synonym	"(2S)-2-amino-4-(carboxymethyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N4-(carboxymethyl)-butanediamic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl glycine isopeptide (Asn-Gly)" EXACT UniProt-feature []
synonym	"CROSSLNK Isoaspartyl glycine isopeptide (Gly-Asn)" EXACT UniProt-feature []
synonym	"isoaspartyl glycine" EXACT RESID-alternate []
synonym	"N-(L-isoaspartyl)-glycine" EXACT RESID-name []
synonym	"N-beta-aspartylglycine" EXACT RESID-alternate []
synonym	"N4-(carboxymethyl)-asparagine" EXACT RESID-alternate []
synonym	"XLNK-4Asp-NGly(Asn)" EXACT PSI-MOD-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 6 H 7 N 2 O 3"
xref	MassAvg: "155.13"
xref	MassMono: "155.045667"
xref	Origin: "G, N"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia
is_a	MOD:01928 N-(L-isoaspartyl)-glycine ! N-(L-isoaspartyl)-glycine

2.136. MOD:00136 pyruvic acid (Cys)

Table 138. Term [MOD:00136]
id	MOD:00136
name	pyruvic acid (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to pyruvic acid." [PubMed:10085076, PubMed:3042771, PubMed:8464063, RESID:AA0127#CYS, UniMod:382]
subset	PSI-MOD-slim
synonym	"2-oxopropanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES Pyruvic acid (Cys)" EXACT UniProt-feature []
synonym	"Pyruv(Cys)" EXACT PSI-MOD-label []
synonym	"pyruvic acid" EXACT RESID-name []
xref	DiffAvg: "-33.09"
xref	DiffFormula: "C 0 H -3 N -1 O 1 S -1"
xref	DiffMono: "-33.003705"
xref	Formula: "C 3 H 3 O 2"
xref	MassAvg: "71.06"
xref	MassMono: "71.013304"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01154 pyruvic acid ! pyruvic acid

2.137. MOD:00137 L-3-phenyllactic acid

Table 139. Term [MOD:00137]
id	MOD:00137
name	L-3-phenyllactic acid
def	"A protein modification that effectively converts an L-phenylalanine residue into L-3-phenyllactic acid." [PubMed:1973541, RESID:AA0128, UniMod:7#F]
comment	This modification is not the result of deamidation, instead the alpha amino group is replaced with an hydroxyl group.
synonym	"(2S)-2-hydroxy-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"Deamidated" RELATED UniMod-interim []
synonym	"Deamidation" RELATED UniMod-description []
synonym	"L-3-phenyllactic acid" EXACT RESID-name []
synonym	"MOD_RES 3-phenyllactic acid" EXACT UniProt-feature []
xref	DiffAvg: "0.98"
xref	DiffFormula: "C 0 H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 9 H 9 O 2"
xref	MassAvg: "149.17"
xref	MassMono: "149.060255"
xref	Origin: "F"
xref	TermSpec: "N-term"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.138. MOD:00138 2-oxobutanoic acid

Table 140. Term [MOD:00138]
id	MOD:00138
name	2-oxobutanoic acid
def	"A protein modification that effectively converts an L-threonine residue into 2-oxobutanoic acid." [PubMed:15023056, PubMed:1680314, PubMed:2253617, PubMed:2764678, RESID:AA0129, UniMod:385#T]
synonym	"2-ketobutyric acid" EXACT RESID-alternate []
synonym	"2-oxobutanoic acid" EXACT RESID-name []
synonym	"2-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-oxobutyric acid" EXACT RESID-alternate []
synonym	"Ammonia-loss" RELATED UniMod-interim []
synonym	"Loss of ammonia" RELATED UniMod-description []
synonym	"MOD_RES 2-oxobutanoic acid" EXACT UniProt-feature []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 4 H 5 O 2"
xref	MassAvg: "85.08"
xref	MassMono: "85.028954"
xref	Origin: "T"
xref	TermSpec: "N-term"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01160 deaminated residue ! deaminated residue

2.139. MOD:00139 N2-succinyl-L-tryptophan

Table 141. Term [MOD:00139]
id	MOD:00139
name	N2-succinyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N2-succinyl-L-tryptophan." [PubMed:11857757, PubMed:12175151, PubMed:8471040, RESID:AA0130, UniMod:64#N-term]
synonym	"(2S)-2-(3-carboxypropanoyl)amino-3-(1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-amino-(6,7-dihydro-6,7-dioxo-1H-indole)-3-propanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N2-succinyltryptophan" EXACT UniProt-feature []
synonym	"N2-succinyl-L-tryptophan" EXACT RESID-name []
synonym	"Succinic anhydride labeling reagent light form (N-term)" RELATED UniMod-description []
synonym	"Succinyl" RELATED PSI-MS-label []
xref	DiffAvg: "100.07"
xref	DiffFormula: "C 4 H 4 N 0 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "C 15 H 15 N 2 O 4"
xref	MassAvg: "287.29"
xref	MassMono: "287.103182"
xref	Origin: "W"
xref	TermSpec: "N-term"
is_a	MOD:00457 alpha-amino succinylated residue ! alpha-amino succinylated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.140. MOD:00140 S-phycocyanobilin-L-cysteine

Table 142. Term [MOD:00140]
id	MOD:00140
name	S-phycocyanobilin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound phycocyanobilin." [ChEBI:15617, DeltaMass:0, PubMed:16644722, PubMed:3208761, PubMed:3838747, PubMed:7918400, RESID:AA0131, UniMod:387#C]
comment	From DeltaMass: Average Mass: 587.
synonym	"(2R,3R)-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-18-ethyl-1,2,3,19,21,22,24-heptahydro-2,7,13,17-tetramethyl-1,19-dioxo-(21H,22H,24H)-bilin-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"(2R,3R)-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-18-ethyl-2,7,13,17-tetramethyl-1,2,3,19,21,22,24-heptahydrobilin-1,19(21H,22H,24H)-dione" EXACT RESID-systematic []
synonym	"BINDING Phycocyanobilin chromophore (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"PCB" EXACT RESID-alternate []
synonym	"phycobilin cysteine" EXACT RESID-alternate []
synonym	"Phycocyanobilin" RELATED PSI-MS-label []
synonym	"phycocyanobilin" RELATED UniMod-description []
synonym	"phycocyanobilin cysteine adduct" EXACT RESID-alternate []
synonym	"S-Phycocyanobilin (on Cysteine)" EXACT DeltaMass-label []
synonym	"S-phycocyanobilin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "586.69"
xref	DiffFormula: "C 33 H 38 N 4 O 6 S 0"
xref	DiffMono: "586.279135"
xref	Formula: "C 36 H 43 N 5 O 7 S 1"
xref	MassAvg: "689.83"
xref	MassMono: "689.288320"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.141. MOD:00141 S-phycoerythrobilin-L-cysteine

Table 143. Term [MOD:00141]
id	MOD:00141
name	S-phycoerythrobilin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound phycoerythrobilin." [ChEBI:15618, PubMed:14588022, PubMed:3208761, PubMed:3838747, PubMed:8876649, RESID:AA0132, UniMod:388#C]
synonym	"(2S,3R,16R)-18-ethenyl-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-2,3,15,16-tetrahydrobilin-1,19(21H,22H,24H)-dione" EXACT RESID-systematic []
synonym	"18-ethenyl-3-[1-((2-amino-2-carboxy)ethylsulfanyl)ethyl]-2,3,15,16-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-(21H,22H,24H)-bilin-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"BINDING Phycoerythrobilin chromophore (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"PEB" EXACT RESID-alternate []
synonym	"Phycoerythrobilin" RELATED PSI-MS-label []
synonym	"phycoerythrobilin" RELATED UniMod-description []
synonym	"phycoerythrobilin cysteine adduct" EXACT RESID-alternate []
synonym	"S-phycoerythrobilin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "588.70"
xref	DiffFormula: "C 33 H 40 N 4 O 6 S 0"
xref	DiffMono: "588.294785"
xref	Formula: "C 36 H 45 N 5 O 7 S 1"
xref	MassAvg: "691.84"
xref	MassMono: "691.303970"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.142. MOD:00142 S-phytochromobilin-L-cysteine

Table 144. Term [MOD:00142]
id	MOD:00142
name	S-phytochromobilin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound phytochromobilin." [ChEBI:15619, PubMed:1634523, PubMed:16593380, PubMed:3208761, PubMed:7918400, RESID:AA0133, UniMod:389#C]
synonym	"(2R,3R)-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-18-ethyl-2,7,13,17-tetramethyl-1,2,3,19,21,22,24-heptahydrobilin-1,19(21H,22H,24H)-dione" EXACT RESID-systematic []
synonym	"18-ethenyl-3-[1-((2-amino-2-carboxy)ethylsulfanyl)ethyl]-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"BINDING Phytochromobilin chromophore (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"phytochrome chromophore" EXACT RESID-alternate []
synonym	"Phytochromobilin" RELATED PSI-MS-label []
synonym	"phytochromobilin" RELATED UniMod-description []
synonym	"phytochromobilin cysteine adduct" EXACT RESID-alternate []
synonym	"S-phytochromobilin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "584.67"
xref	DiffFormula: "C 33 H 36 N 4 O 6 S 0"
xref	DiffMono: "584.263485"
xref	Formula: "C 36 H 41 N 5 O 7 S 1"
xref	MassAvg: "687.81"
xref	MassMono: "687.272670"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.143. MOD:00143 heme-bis-L-cysteine

Table 145. Term [MOD:00143]
id	MOD:00143
name	heme-bis-L-cysteine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [ChEBI:17627, PubMed:5545094, PubMed:8827449, RESID:AA0134]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(7,12-bis[(1S)-1-([(2R)-2-amino-2-carboxyethyl]sulfanyl)ethyl]-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-bis[2-carboxyethyl]-N21,N22,N23,N24)-ferrate" EXACT RESID-systematic []
synonym	"2,4-bis[1-(S-cysteinyl)ethyl]protoporphyrin IX" EXACT RESID-alternate []
synonym	"BINDING Heme (covalent)" EXACT UniProt-feature []
synonym	"biscysteinyl heme" EXACT RESID-alternate []
synonym	"heme-bis-L-cysteine" EXACT RESID-name []
synonym	"HemeCys2" EXACT PSI-MOD-label []
xref	DiffAvg: "616.50"
xref	DiffFormula: "C 34 Fe 1 H 32 N 4 O 4 S 0"
xref	DiffMono: "616.177293"
xref	Formula: "C 40 Fe 1 H 42 N 6 O 6 S 2"
xref	MassAvg: "822.78"
xref	MassMono: "822.195663"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.144. MOD:00144 heme-L-cysteine

Table 146. Term [MOD:00144]
id	MOD:00144
name	heme-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [ChEBI:17627, DeltaMass:0, PubMed:170910, PubMed:192772, PubMed:2536325, PubMed:9535866, RESID:AA0135, UniMod:390#C]
comment	From DeltaMass: Average Mass: 617.
subset	PSI-MOD-slim
synonym	"(12-ethenyl-7-[(1S)-1-([(2R)-2-amino-2-carboxyethyl]sulfanyl)ethyl]-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-bis[2-carboxyethyl]-N21,N22,N23,N24)-ferrate" EXACT RESID-systematic []
synonym	"4-[1-(S-cysteinyl)ethyl]protoporphyrin IX" EXACT RESID-alternate []
synonym	"BINDING Heme (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"cysteinyl heme" EXACT RESID-alternate []
synonym	"Heme" RELATED PSI-MS-label []
synonym	"heme" RELATED UniMod-description []
synonym	"heme-L-cysteine" EXACT RESID-name []
synonym	"HemeCys1" EXACT PSI-MOD-label []
synonym	"S-Heme (on Cysteine)" EXACT DeltaMass-label []
xref	DiffAvg: "616.50"
xref	DiffFormula: "C 34 Fe 1 H 32 N 4 O 4 S 0"
xref	DiffMono: "616.177293"
xref	Formula: "C 37 Fe 1 H 37 N 5 O 5 S 1"
xref	MassAvg: "719.64"
xref	MassMono: "719.186478"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.145. MOD:00145 tetrakis-L-cysteinyl iron

Table 147. Term [MOD:00145]
id	MOD:00145
name	tetrakis-L-cysteinyl iron
def	"A protein modification that effectively converts four L-cysteine residues iron atom to tetrakis-L-cysteinyl iron." [PubMed:1303768, PubMed:2244884, RESID:AA0136]
comment	Cross-link 4.
synonym	"METAL Iron" EXACT UniProt-feature []
synonym	"tetrakis(cysteinato-kappaS)-iron" EXACT RESID-systematic []
synonym	"tetrakis-L-cysteinyl iron" EXACT RESID-name []
xref	DiffAvg: "51.81"
xref	DiffFormula: "C 0 Fe 1 H -4 N 0 O 0 S 0"
xref	DiffMono: "51.904735"
xref	FormalCharge: "2-"
xref	Formula: "C 12 Fe 1 H 16 N 4 O 4 S 4"
xref	MassAvg: "464.37"
xref	MassMono: "463.941474"
xref	Origin: "C, C, C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00738 iron containing modified residue ! iron containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.146. MOD:00146 tetrakis-L-cysteinyl diiron disulfide

Table 148. Term [MOD:00146]
id	MOD:00146
name	tetrakis-L-cysteinyl diiron disulfide
def	"A protein modification that effectively converts four L-cysteine residues and a two-iron two-sulfur cluster to tetrakis-L-cysteinyl diiron disulfide." [PubMed:2123937, PubMed:6801028, PubMed:7763242, PubMed:8688437, RESID:AA0137]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (2Fe-2S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (2Fe-2S); shared with dimeric partner" EXACT UniProt-feature []
synonym	"tetrakis-L-cysteinyl diiron disulfide" EXACT RESID-name []
synonym	"tetrakiscysteinato-1kappa(2)S,2kappa(2)S-di-mu-sulfido-diiron" EXACT RESID-systematic []
xref	DiffAvg: "171.78"
xref	DiffFormula: "C 0 Fe 2 H -4 N 0 O 0 S 2"
xref	DiffMono: "171.783814"
xref	FormalCharge: "2-"
xref	Formula: "C 12 Fe 2 H 16 N 4 O 4 S 6"
xref	MassAvg: "584.34"
xref	MassMono: "583.820553"
xref	Origin: "C, C, C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.147. MOD:00147 hexakis-L-cysteinyl triiron trisulfide

Table 149. Term [MOD:00147]
id	MOD:00147
name	hexakis-L-cysteinyl triiron trisulfide
def	"A protein modification that effectively converts six L-cysteine residues and a three-iron three-sulfur cluster to hexakis-L-cysteinyl triiron trisulfide." [PubMed:3379067, PubMed:3932661, PubMed:7354058, RESID:AA0138]
comment	Cross-link 6. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"hexakis-L-cysteinyl triiron trisulfide" EXACT RESID-name []
synonym	"tri-mu-sulfido-hexakiscysteinato-1kappa(2)S,2kappa(2)S,3kappa(2)S-triiron" EXACT RESID-systematic []
synonym	"tri-mu-sulfidotris(biscysteinato-kappaS-iron)" EXACT RESID-alternate []
xref	DiffAvg: "257.67"
xref	DiffFormula: "C 0 Fe 3 H -6 N 0 O 0 S 3"
xref	DiffMono: "257.675721"
xref	FormalCharge: "3-"
xref	Formula: "C 18 Fe 3 H 24 N 6 O 6 S 9"
xref	MassAvg: "876.50"
xref	MassMono: "875.730830"
xref	Origin: "C, C, C, C, C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.148. MOD:00148 tris-L-cysteinyl triiron tetrasulfide

Table 150. Term [MOD:00148]
id	MOD:00148
name	tris-L-cysteinyl triiron tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues and a three-iron four-sulfur cluster to tris-L-cysteinyl triiron tetrasulfide." [PubMed:10555576, PubMed:2056535, PubMed:3422475, PubMed:6848518, PubMed:7819255, PubMed:9063899, RESID:AA0139]
comment	Cross-link 3.
synonym	"METAL Iron-sulfur (3Fe-4S)" EXACT UniProt-feature []
synonym	"mu3-sulfido tri-mu-sulfido tris-S-L-cysteinyl triiron" EXACT RESID-alternate []
synonym	"mu3-sulfido-tri-mu-sulfido-triscysteinato-1kappaS,2kappaS,3kappaS-triiron" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl triiron tetrasulfide" EXACT RESID-name []
synonym	"tris-L-cysteinyl triiron tetrasulfide C3 cluster" EXACT RESID-alternate []
synonym	"tris-L-cysteinyl triiron tetrasulfide cubane form" EXACT RESID-alternate []
synonym	"tris-L-cysteinyl triiron tetrasulfide cuboid cluster" EXACT RESID-alternate []
synonym	"tris-L-cysteinyl triiron tetrasulfide trigonal cluster" EXACT RESID-alternate []
xref	DiffAvg: "292.75"
xref	DiffFormula: "C 0 Fe 3 H -3 N 0 O 0 S 4"
xref	DiffMono: "292.671267"
xref	FormalCharge: "3-"
xref	Formula: "C 9 Fe 3 H 12 N 3 O 3 S 7"
xref	MassAvg: "602.17"
xref	MassMono: "601.698821"
xref	Origin: "C, C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.149. MOD:00149 tetrakis-L-cysteinyl tetrairon tetrasulfide

Table 151. Term [MOD:00149]
id	MOD:00149
name	tetrakis-L-cysteinyl tetrairon tetrasulfide
def	"A protein modification that effectively converts four L-cysteine residues and a four-iron four-sulfur cluster to tetrakis-L-cysteinyl tetrairon tetrasulfide." [PubMed:3351918, PubMed:7803404, PubMed:7819196, PubMed:932007, RESID:AA0140]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (4Fe-4S); shared with dimeric partner" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfido-tetrakis(cysteinato)-1kappaS,2kappaS,3kappaS,4kappaS-tetrahedro-tetrairon" EXACT RESID-systematic []
synonym	"tetra-mu3-sulfidotetrakis(S-cysteinyliron)" EXACT RESID-alternate []
synonym	"tetrakis-L-cysteinyl tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 12 Fe 4 H 16 N 4 O 4 S 8"
xref	MassAvg: "760.15"
xref	MassMono: "759.634570"
xref	Origin: "C, C, C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.150. MOD:00150 L-cysteinyl-L-histidino-homocitryl molybdenum heptairon nonasulfide

Table 152. Term [MOD:00150]
id	MOD:00150
name	L-cysteinyl-L-histidino-homocitryl molybdenum heptairon nonasulfide
def	"A protein modification that effectively converts an L-cysteine residue, an L-histidine residue, homocitric acid and a one-molybdenum seven-iron nine-sulfur cluster to L-cysteinyl-L-histidino-homocitryl molybdenum heptairon nonasulfide." [PubMed:10525412, PubMed:12215645, PubMed:12733878, PubMed:1529354, PubMed:8027059, RESID:AA0141]
comment	Cross-link 2; incidental to RESID:AA0300.
synonym	"cysteinato-8kappaS-histidino-1kappaN(tau)-[(2R)-4-carboxy-2-(carboxymethyl)-2-oxidobutanoate-1kappaO(1),1kappaO(2)]-mu6-carbido-2:3:4:5:6:7kappa(6)C-hexa-mu3-sulfido-1:2:3kappa(3)S;1:2:4kappa(3)S;1:3:4kappa(3)S;5:6:8kappa(3)S;5:7:8kappa(3)S;6:7:8kappa(3)S-tri-mu2-sulfido-2:5kappa(2)S;3:6kappa(2)S;4:7kappa(2)S molybdenum heptairon" EXACT RESID-systematic []
synonym	"L-cysteinyl-L-histidino-homocitryl molybdenum heptairon nonasulfide carbide" EXACT RESID-name []
synonym	"nitrogenase iron-molybdenum cofactor" EXACT RESID-alternate []
xref	DiffAvg: "991.53"
xref	DiffFormula: "C 7 Fe 7 H 6 Mo 1 N 1 O 7 S 9"
xref	DiffMono: "993.213036"
xref	Formula: "C 16 Fe 7 H 18 Mo 1 N 5 O 9 S 10"
xref	MassAvg: "1231.81"
xref	MassMono: "1233.281133"
xref	Origin: "C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00743 molybdenum containing modified residue ! molybdenum containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.151. MOD:00151 L-cysteinyl molybdopterin

Table 153. Term [MOD:00151]
id	MOD:00151
name	L-cysteinyl molybdopterin
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteinyl molybdopterin." [PubMed:14527393, PubMed:7878465, PubMed:9428520, RESID:AA0142, UniMod:391#C]
subset	PSI-MOD-slim
synonym	"(4R,5aR,11aR)-8-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-4,5a,6,9,10,11,11a-heptahydro-4-(phosphoric acid)methyl-2,2,10-trioxo-pteridino[6,7-5,6]pyrano[3,4-4,3][1,2,5]molybdadithiolene" EXACT RESID-systematic []
synonym	"cysteinyl Mo-molybdopterin" EXACT RESID-alternate []
synonym	"cysteinyl Mo-pterin" EXACT RESID-alternate []
synonym	"L-cysteinyl molybdopterin" EXACT RESID-name []
synonym	"METAL Molybdenum-pterin" EXACT UniProt-feature []
synonym	"molybdoenzyme molybdenum cofactor" EXACT RESID-alternate []
synonym	"Molybdopterin" RELATED PSI-MS-label []
synonym	"molybdopterin" RELATED UniMod-description []
synonym	"MoPterCys" EXACT PSI-MOD-label []
xref	DiffAvg: "520.27"
xref	DiffFormula: "C 10 H 11 Mo 1 N 5 O 8 P 1 S 2"
xref	DiffMono: "521.884074"
xref	Formula: "C 13 H 16 Mo 1 N 6 O 9 P 1 S 3"
xref	MassAvg: "623.41"
xref	MassMono: "624.893259"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.152. MOD:00152 S-(8alpha-FAD)-L-cysteine

Table 154. Term [MOD:00152]
id	MOD:00152
name	S-(8alpha-FAD)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S'-(8alpha-FAD)-L-cystine." [PubMed:10220347, RESID:AA0143, UniMod:50#C]
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine]sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"8alpha-(S-cysteinyl)FAD" EXACT RESID-alternate []
synonym	"FAD" RELATED PSI-MS-label []
synonym	"Flavin adenine dinucleotide" RELATED UniMod-description []
synonym	"MOD_RES S-8alpha-FAD cysteine" EXACT UniProt-feature []
synonym	"S-(8alpha-FAD)-L-cysteine" EXACT RESID-name []
synonym	"S8aFADCys" EXACT PSI-MOD-label []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2 S 0"
xref	DiffMono: "783.141485"
xref	Formula: "C 30 H 36 N 10 O 16 P 2 S 1"
xref	MassAvg: "886.68"
xref	MassMono: "886.150669"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.153. MOD:00153 3'-(8alpha-FAD)-L-histidine

Table 155. Term [MOD:00153]
id	MOD:00153
name	3'-(8alpha-FAD)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 3'-(8alpha-FAD)-L-histidine." [PubMed:241294, PubMed:8076, RESID:AA0144, UniMod:50#H]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(3-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine]imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"3'-(8alpha-FAD)-L-histidine" EXACT RESID-name []
synonym	"8alpha-(N(delta)-histidyl)FAD" EXACT RESID-alternate []
synonym	"8alpha-(N3'-histidyl)FAD" EXACT RESID-alternate []
synonym	"8alpha-N1-histidyl FAD" RELATED RESID-misnomer []
synonym	"FAD" RELATED PSI-MS-label []
synonym	"Flavin adenine dinucleotide" RELATED UniMod-description []
synonym	"MOD_RES Pros-8alpha-FAD histidine" EXACT UniProt-feature []
synonym	"N(pi)-(8alpha-FAD)-histidine" EXACT RESID-alternate []
synonym	"Np8aFADHis" EXACT PSI-MOD-label []
synonym	"pros-(8alpha-FAD)-histidine" EXACT RESID-alternate []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2"
xref	DiffMono: "783.141485"
xref	Formula: "C 33 H 38 N 12 O 16 P 2"
xref	MassAvg: "920.68"
xref	MassMono: "920.200396"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.154. MOD:00154 O4'-(8alpha-FAD)-L-tyrosine

Table 156. Term [MOD:00154]
id	MOD:00154
name	O4'-(8alpha-FAD)-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-(8alpha-FAD)-L-tyrosine." [DeltaMass:0, PubMed:7391034, RESID:AA0145, UniMod:50#Y]
comment	From DeltaMass: Average Mass: 783
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine]oxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"8alpha-(O4'-tyrosyl)FAD" EXACT RESID-alternate []
synonym	"FAD" RELATED PSI-MS-label []
synonym	"Flavin adenine dinucleotide" RELATED UniMod-description []
synonym	"MOD_RES O-8alpha-FAD tyrosine" EXACT UniProt-feature []
synonym	"O-8 alpha-Flavin [FAD])- (of Tyrosine)" EXACT DeltaMass-label []
synonym	"O4'-(8alpha-FAD)-L-tyrosine" EXACT RESID-name []
synonym	"O8aFADTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2"
xref	DiffMono: "783.141485"
xref	Formula: "C 36 H 40 N 10 O 17 P 2"
xref	MassAvg: "946.72"
xref	MassMono: "946.204813"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.155. MOD:00155 3'-hydroxylation of L-tyrosine to L-3',4'-dihydroxyphenylalanine

Table 157. Term [MOD:00155]
id	MOD:00155
name	3'-hydroxylation of L-tyrosine to L-3',4'-dihydroxyphenylalanine
def	"A protein modification that effectively converts an L-tyrosine residue to L-3',4'-dihydroxyphenylalanine." [DeltaMass:0, OMSSA:194, OMSSA:64, PubMed:1610822, PubMed:1903612, PubMed:3734192, RESID:AA0146, UniMod:35#Y]
comment	incidental to RESID:AA0368 From DeltaMass: Average Mass: 16
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3,4-Dihydroxy-Phenylalanine (from Tyrosine) (DOPA)" EXACT DeltaMass-label []
synonym	"3HyTyr" EXACT PSI-MOD-label []
synonym	"hydroxylationy" EXACT OMSSA-label []
synonym	"L-3',4'-dihydroxyphenylalanine" EXACT RESID-name []
synonym	"L-3'-hydroxytyrosine" EXACT RESID-alternate []
synonym	"L-DOPA" EXACT RESID-alternate []
synonym	"levodopa" EXACT RESID-alternate []
synonym	"mod194" EXACT OMSSA-label []
synonym	"MOD_RES 3',4'-dihydroxyphenylalanine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 9 H 9 N 1 O 3"
xref	MassAvg: "179.18"
xref	MassMono: "179.058243"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00707 hydroxylated tyrosine ! hydroxylated tyrosine

2.156. MOD:00156 oxidation of tyrosine to L-2',4',5'-topaquinone

Table 158. Term [MOD:00156]
id	MOD:00156
name	oxidation of tyrosine to L-2',4',5'-topaquinone
def	"A protein modification that effectively converts an L-tyrosine residue to an L-2',4',5'-topaquinone." [ChEBI:21187, PubMed:10387067, PubMed:1457410, PubMed:1569055, PubMed:2111581, RESID:AA0147, UniMod:392#Y]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(5-hydroxy-2,5-cyclohexadien-1,4-dion-2-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2,4,5-trihydroxyphenylalanine quinone" EXACT RESID-alternate []
synonym	"5-(2-carboxy-2-aminoethyl)-2-hydroxy-1,4-benzoquinone" EXACT RESID-alternate []
synonym	"L-2',4',5'-topaquinone" EXACT RESID-name []
synonym	"L-2,4,5-TOPAquinone" EXACT RESID-alternate []
synonym	"MOD_RES 2',4',5'-topaquinone" EXACT UniProt-feature []
synonym	"Quinone" RELATED PSI-MS-label []
synonym	"quinone" RELATED UniMod-description []
synonym	"TopaQ" EXACT PSI-MOD-label []
synonym	"TPQ" EXACT RESID-alternate []
xref	DiffAvg: "29.98"
xref	DiffFormula: "C 0 H -2 N 0 O 2"
xref	DiffMono: "29.974179"
xref	Formula: "C 9 H 7 N 1 O 4"
xref	MassAvg: "193.16"
xref	MassMono: "193.037508"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.157. MOD:00157 oxidation of tryptophan to L-tryptophyl quinone

Table 159. Term [MOD:00157]
id	MOD:00157
name	oxidation of tryptophan to L-tryptophyl quinone
def	"A protein modification that effectively converts an L-tryptophan residue to an L-tryptophan quinone." [DeltaMass:0, PubMed:2028257, RESID:AA0148, UniMod:392#W]
comment	incidental to RESID:AA0149; incidental to RESID:AA0313; From DeltaMass: Average Mass: 30.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(6,7-dioxo-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(6,7-dioxo-6,7-dihydro-1H-indol-3-yl)-propionic acid" EXACT RESID-alternate []
synonym	"3-[(2S)-2-amino-2-carboxyethyl]-6,7-indolinedione" EXACT RESID-alternate []
synonym	"6,7 Dione (from Tryptophan)" EXACT DeltaMass-label []
synonym	"L-tryptophyl quinone" EXACT RESID-name []
synonym	"MOD_RES Tryptophylquinone" EXACT UniProt-feature []
synonym	"N-(3-carboxy-1-oxopropyl)-L-tryptophan" EXACT RESID-alternate []
synonym	"Quinone" RELATED PSI-MS-label []
synonym	"quinone" RELATED UniMod-description []
synonym	"TrpQ" EXACT PSI-MOD-label []
xref	DiffAvg: "29.98"
xref	DiffFormula: "C 0 H -2 N 0 O 2"
xref	DiffMono: "29.974179"
xref	Formula: "C 11 H 8 N 2 O 3"
xref	MassAvg: "216.20"
xref	MassMono: "216.053492"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.158. MOD:00158 4'-(L-tryptophan)-L-tryptophyl quinone

Table 160. Term [MOD:00158]
id	MOD:00158
name	4'-(L-tryptophan)-L-tryptophyl quinone
def	"A protein modification that effectively cross-links two L-tryptophan residues by a carbon-carbon bond to form 4'-(L-tryptophan)-L-tryptophyl quinone." [ChEBI:20251, DeltaMass:0, PubMed:2028257, RESID:AA0149]
comment	Cross-link 2; secondary to RESID:AA0148; From DeltaMass: Average Mass: 28.
subset	PSI-MOD-slim
synonym	"2,4-BisTrp-6,7-dione (from Tryptophan)" EXACT DeltaMass-label []
synonym	"2-amino-3-[2-[2-amino-3-(2-carboxyethyl)-6,7-dioxo-1H-indol-4-yl]-1H-indol-3-yl]propanoic acid" EXACT RESID-alternate []
synonym	"3-[(2S)-2-amino-2-carboxyethyl]-4-(3-[(2S)-2-amino-2-carboxyethyl]-1H-indol-2-yl)-6,7-indolinedione" EXACT RESID-systematic []
synonym	"4'-tryptophan-tryptophylquinone" EXACT RESID-alternate []
synonym	"4-(2'-tryptophyl)tryptophan-6,7-dione" EXACT RESID-alternate []
synonym	"4-(L-tryptophan-2-yl)-L-tryptophyl quinone" EXACT RESID-name []
synonym	"alpha,alpha'-diamino-6',7'-dihydro-6',7'-dioxo-(2,4'-bi-1H-indole)-3,3'-dipropanoic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Tryptophan tryptophylquinone (Trp-Trp)" EXACT UniProt-feature []
synonym	"TTQ" EXACT RESID-alternate []
synonym	"XLNK-4’Trp-TrpQ" EXACT PSI-MOD-label []
xref	DiffAvg: "27.97"
xref	DiffFormula: "C 0 H -4 N 0 O 2"
xref	DiffMono: "27.958529"
xref	Formula: "C 22 H 16 N 4 O 4"
xref	MassAvg: "400.39"
xref	MassMono: "400.117155"
xref	Origin: "W, W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.159. MOD:00159 O-phosphopantetheine-L-serine

Table 161. Term [MOD:00159]
id	MOD:00159
name	O-phosphopantetheine-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-phosphopantetheine-L-serine." [DeltaMass:0, PubMed:10320345, PubMed:10997907, PubMed:12057197, PubMed:12869567, PubMed:4568609, RESID:AA0150, UniMod:49#S]
comment	UniMod has DiffFormula C 11 H 20 N 2 O 6 P 1 S 1 From DeltaMass: Average Mass: 339
subset	PSI-MOD-slim
synonym	"(2R)-2-hydroxy-3,3-dimethyl-4-[(2S)-2-amino-2-carboxyethyl]phosphonato-N-(3-oxo-3-[(2-sulfanylethyl)amino]propyl)butanamide" EXACT RESID-systematic []
synonym	"4'-Phosphopantetheine" EXACT DeltaMass-label []
synonym	"MOD_RES O-(pantetheine 4'-phosphoryl)serine" EXACT UniProt-feature []
synonym	"O-phosphopantetheine-L-serine" EXACT RESID-name []
synonym	"OPpantSer" EXACT PSI-MOD-label []
synonym	"Phosphopantetheine" RELATED PSI-MS-label []
synonym	"Phosphopantetheine" RELATED UniMod-description []
xref	DiffAvg: "340.33"
xref	DiffFormula: "C 11 H 21 N 2 O 6 P 1 S 1"
xref	DiffMono: "340.085794"
xref	Formula: "C 14 H 26 N 3 O 8 P 1 S 1"
xref	MassAvg: "427.41"
xref	MassMono: "427.117822"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.160. MOD:00160 N4-glycosyl-L-asparagine

Table 162. Term [MOD:00160]
id	MOD:00160
name	N4-glycosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine." [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var]
subset	PSI-MOD-slim
synonym	"N4GlycoAsn" EXACT PSI-MOD-label []
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00006 N-glycosylated residue ! N-glycosylated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.161. MOD:00161 S-glucosyl-L-cysteine

Table 163. Term [MOD:00161]
id	MOD:00161
name	S-glucosyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-glucosylated L-cysteine." [PubMed:1145128, PubMed:15279557, PubMed:5286858, RESID:AA0152, UniMod:41#C]
synonym	"(2R)-2-amino-3-[(beta-D-glucopyranosyl)sulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD S-linked (Glc)" EXACT UniProt-feature []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
synonym	"S-(beta-D-glucopyranosyl)cysteine" EXACT RESID-alternate []
synonym	"S-glucosyl-L-cysteine" EXACT RESID-name []
synonym	"S-glycosyl-cysteine" EXACT RESID-alternate []
synonym	"SGlcCys" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5 S 0"
xref	DiffMono: "162.052823"
xref	Formula: "C 9 H 15 N 1 O 6 S 1"
xref	MassAvg: "265.28"
xref	MassMono: "265.062008"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00426 S-glycosylated residue ! S-glycosylated residue
is_a	MOD:00433 glucosylated residue ! glucosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.162. MOD:00162 O5-glucosylgalactosyl-L-hydroxylysine

Table 164. Term [MOD:00162]
id	MOD:00162
name	O5-glucosylgalactosyl-L-hydroxylysine
def	"A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine." [PubMed:15149698, PubMed:4288358, PubMed:4319110, RESID:AA0153, UniMod:393]
comment	Secondary to RESID:AA0028.
subset	PSI-MOD-slim
synonym	"(2S,5R)-2,6-diamino-5-[2-O-(alpha-D-glucopyranosyl)-beta-D-galactopyranosyloxy]hexanoic acid" EXACT RESID-systematic []
synonym	"5-(2-O-alpha-D-glucopyranosyl-beta-D-galactopyranosyl)oxy-L-lysine" EXACT RESID-alternate []
synonym	"Glucosylgalactosyl" RELATED PSI-MS-label []
synonym	"glucosylgalactosyl hydroxylysine" RELATED UniMod-description []
synonym	"O5-glucosylgalactosyl-L-hydroxylysine" EXACT RESID-name []
synonym	"OGlcGal5HyLys" EXACT PSI-MOD-label []
xref	DiffAvg: "340.28"
xref	DiffFormula: "C 12 H 20 N 0 O 11"
xref	DiffMono: "340.100561"
xref	Formula: "C 18 H 32 N 2 O 12"
xref	MassAvg: "468.46"
xref	MassMono: "468.195524"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00476 galactosylated residue ! galactosylated residue
is_a	MOD:00726 glucosylated ! glucosylated

2.163. MOD:00163 O-(N-acetylamino)galactosyl-L-serine

Table 165. Term [MOD:00163]
id	MOD:00163
name	O-(N-acetylamino)galactosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine." [PubMed:115869, PubMed:16005634, PubMed:3086323, PubMed:8948436, PubMed:9092502, RESID:AA0154]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(2-acetamido-2-deoxy-alpha-D-galactopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GalNAc)" EXACT UniProt-feature []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"mucin type O-glycosylserine" EXACT RESID-alternate []
synonym	"O-(N-acetylamino)galactosyl-L-serine" EXACT RESID-name []
synonym	"O3-(N-acetylgalactosaminyl)serine" EXACT RESID-alternate []
synonym	"OGalNAcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 11 H 18 N 2 O 7"
xref	MassAvg: "290.27"
xref	MassMono: "290.111401"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00563 N-acetylaminogalactosylated residue ! N-acetylaminogalactosylated residue
is_a	MOD:01675 O-(N-acetylamino)hexosyl-L-serine ! O-(N-acetylamino)hexosyl-L-serine

2.164. MOD:00164 O-(N-acetylamino)galactosyl-L-threonine

Table 166. Term [MOD:00164]
id	MOD:00164
name	O-(N-acetylamino)galactosyl-L-threonine
def	"A protein modification that effectively converts an L-asparagine residue to O-(N-acetylaminogalactosyl)-L-threonine." [PubMed:16005634, PubMed:1997327, PubMed:3086323, PubMed:8948436, PubMed:9092502, RESID:AA0155]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(2-acetamido-2-deoxy-alpha-D-galactopyranosyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GalNAc)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (HexNAc)" EXACT UniProt-feature []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"mucin type O-glycosylthreonine" EXACT RESID-alternate []
synonym	"O-(N-acetylamino)galactosyl-L-threonine" EXACT RESID-name []
synonym	"O3-(N-acetylgalactosaminyl)threonine" EXACT RESID-alternate []
synonym	"OGalNAcThr" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 20 N 2 O 7"
xref	MassAvg: "304.30"
xref	MassMono: "304.127051"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00563 N-acetylaminogalactosylated residue ! N-acetylaminogalactosylated residue
is_a	MOD:01676 O-(N-acetylamino)hexosyl-L-threonine ! O-(N-acetylamino)hexosyl-L-threonine

2.165. MOD:00165 1'-mannosyl-L-tryptophan

Table 167. Term [MOD:00165]
id	MOD:00165
name	1'-mannosyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 1'-mannosyl-L-tryptophan." [PubMed:1482345, PubMed:16150691, RESID:AA0156]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-glycosyl-L-tryptophan" EXACT RESID-alternate []
synonym	"1'-mannosyl-L-tryptophan" EXACT RESID-name []
synonym	"CARBOHYD N-linked (Man)" EXACT UniProt-feature []
synonym	"N-mannosyl-tryptophan" EXACT RESID-alternate []
synonym	"N1’ManTrp" EXACT PSI-MOD-label []
synonym	"N1-mannosyl-tryptophan" EXACT RESID-alternate []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 17 H 20 N 2 O 6"
xref	MassAvg: "348.36"
xref	MassMono: "348.132136"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00006 N-glycosylated residue ! N-glycosylated residue
is_a	MOD:00595 mannosylated residue ! mannosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.166. MOD:00166 O4'-glucosyl-L-tyrosine

Table 168. Term [MOD:00166]
id	MOD:00166
name	O4'-glucosyl-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-glucosyl-tyrosine." [PubMed:15279557, PubMed:3181138, RESID:AA0157, UniMod:41#Y]
synonym	"(2S)-2-amino-3-(4-alpha-D-glucopyranosyloxy)phenylpropanoic acid" EXACT RESID-systematic []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
synonym	"O4'-glucosyl-L-tyrosine" EXACT RESID-name []
synonym	"O4'-glycosyl-L-tyrosine" EXACT RESID-alternate []
synonym	"O4GlcTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 15 H 19 N 1 O 7"
xref	MassAvg: "325.32"
xref	MassMono: "325.116152"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00433 glucosylated residue ! glucosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:01927 O-glycosyl-L-tyrosine ! O-glycosyl-L-tyrosine

2.167. MOD:00167 N-asparaginyl-glycosylphosphatidylinositolethanolamine

Table 169. Term [MOD:00167]
id	MOD:00167
name	N-asparaginyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-asparagine residue to N-asparaginyl-glycosylphosphatidylinositolethanolamine." [PubMed:1824714, PubMed:8276756, RESID:AA0158]
synonym	"GPIAsn" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated asparagine" EXACT UniProt-feature []
synonym	"N-asparaginyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 6 H 13 N 3 O 6 P 1"
xref	MassAvg: "254.16"
xref	MassMono: "254.054197"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.168. MOD:00168 N-aspartyl-glycosylphosphatidylinositolethanolamine

Table 170. Term [MOD:00168]
id	MOD:00168
name	N-aspartyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-aspartic acid residue to N-(aspart-1-yl)-glycosylphosphatidylinositolethanolamine." [PubMed:7120400, RESID:AA0159]
synonym	"GPIAsp" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated aspartate" EXACT UniProt-feature []
synonym	"N-aspartyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 6 H 12 N 2 O 7 P 1"
xref	MassAvg: "255.14"
xref	MassMono: "255.038212"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.169. MOD:00169 N-cysteinyl-glycosylphosphatidylinositolethanolamine

Table 171. Term [MOD:00169]
id	MOD:00169
name	N-cysteinyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-cysteine residue to N-cysteinyl-glycosylphosphatidylinositolethanolamine." [PubMed:2897081, RESID:AA0160]
synonym	"GPICys" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated cysteine" EXACT UniProt-feature []
synonym	"N-cysteinyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1 S 0"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 12 N 2 O 5 P 1 S 1"
xref	MassAvg: "243.19"
xref	MassMono: "243.020454"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.170. MOD:00170 N-glycyl-glycosylphosphatidylinositolethanolamine

Table 172. Term [MOD:00170]
id	MOD:00170
name	N-glycyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts a glycine residue to N-glycyl-glycosylphosphatidylinositolethanolamine." [PubMed:2341397, RESID:AA0161]
synonym	"GPIGly" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated glycine" EXACT UniProt-feature []
synonym	"N-glycyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 4 H 10 N 2 O 5 P 1"
xref	MassAvg: "197.11"
xref	MassMono: "197.032733"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.171. MOD:00171 N-seryl-glycosylphosphatidylinositolethanolamine

Table 173. Term [MOD:00171]
id	MOD:00171
name	N-seryl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-serine residue to N-seryl-glycosylphosphatidylinositolethanolamine." [PubMed:2111324, PubMed:8448158, RESID:AA0162]
synonym	"GPISer" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated serine" EXACT UniProt-feature []
synonym	"N-seryl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 12 N 2 O 6 P 1"
xref	MassAvg: "227.13"
xref	MassMono: "227.043298"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.172. MOD:00172 N-alanyl-glycosylphosphatidylinositolethanolamine

Table 174. Term [MOD:00172]
id	MOD:00172
name	N-alanyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-alanine residue to N-alanyl-glycosylphosphatidylinositolethanolamine." [PubMed:7682556, PubMed:7744038, RESID:AA0163]
synonym	"GPIAla" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated alanine" EXACT UniProt-feature []
synonym	"N-alanyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 12 N 2 O 5 P 1"
xref	MassAvg: "211.13"
xref	MassMono: "211.048383"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.173. MOD:00173 N-threonyl-glycosylphosphatidylinositolethanolamine

Table 175. Term [MOD:00173]
id	MOD:00173
name	N-threonyl-glycosylphosphatidylinositolethanolamine
def	"A protein modification that effectively converts an L-threonine residue to N-threonyl-glycosylphosphatidylinositolethanolamine." [RESID:AA0164]
synonym	"GPIThr" EXACT PSI-MOD-label []
synonym	"LIPID GPI-anchor amidated threonine" EXACT UniProt-feature []
synonym	"N-threonyl-glycosylphosphatidylinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 6 H 14 N 2 O 6 P 1"
xref	MassAvg: "241.16"
xref	MassMono: "241.058948"
xref	Origin: "T"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00818 glycosylphosphatidylinositolated residue ! glycosylphosphatidylinositolated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.174. MOD:00174 N-glycyl-glycosylsphingolipidinositolethanolamine

Table 176. Term [MOD:00174]
id	MOD:00174
name	N-glycyl-glycosylsphingolipidinositolethanolamine
def	"A protein modification that effectively converts a glycine residue to N-glycyl-glycosylsphingolipidinositolethanolamine." [PubMed:12626404, PubMed:8404891, RESID:AA0165]
synonym	"GSIGly" EXACT PSI-MOD-label []
synonym	"LIPID GPI-like-anchor amidated glycine" EXACT UniProt-feature []
synonym	"N-glycyl-glycosylsphingolipidinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 4 H 10 N 2 O 5 P 1"
xref	MassAvg: "197.11"
xref	MassMono: "197.032733"
xref	Origin: "G"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00466 glycosylsphingolipidinositolated residue ! glycosylsphingolipidinositolated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.175. MOD:00175 N-seryl-glycosylsphingolipidinositolethanolamine

Table 177. Term [MOD:00175]
id	MOD:00175
name	N-seryl-glycosylsphingolipidinositolethanolamine
def	"A protein modification that effectively converts an L-serine residue to N-seryl-glycosylsphingolipidinositolethanolamine." [PubMed:12626404, PubMed:2721485, PubMed:8269952, RESID:AA0166]
synonym	"GSISer" EXACT PSI-MOD-label []
synonym	"LIPID GPI-like-anchor amidated serine" EXACT UniProt-feature []
synonym	"N-seryl-glycosylsphingolipidinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 12 N 2 O 6 P 1"
xref	MassAvg: "227.13"
xref	MassMono: "227.043298"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00466 glycosylsphingolipidinositolated residue ! glycosylsphingolipidinositolated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.176. MOD:00176 O-(phosphoribosyl dephospho-coenzyme A)-L-serine

Table 178. Term [MOD:00176]
id	MOD:00176
name	O-(phosphoribosyl dephospho-coenzyme A)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(phosphoribosyl dephospho-coenzyme A)-L-serine." [PubMed:10924139, PubMed:11052675, PubMed:179809, PubMed:180526, PubMed:368065, RESID:AA0167, UniMod:395#S]
comment	pRibodePcoA
subset	PSI-MOD-slim
synonym	"MOD_RES O-(phosphoribosyl dephospho-coenzyme A)serine" EXACT UniProt-feature []
synonym	"O-(phosphoribosyl dephospho-coenzyme A)-L-serine" EXACT RESID-name []
synonym	"O3-(phosphate-5-ribosyl-alpha-2-adenosine-5-diphosphate pantetheine)-L-serine" EXACT RESID-alternate []
synonym	"O3-(phosphoribosyl dephospho-coenzyme A)-L-serine" EXACT RESID-alternate []
synonym	"O3-2'-(5''-phosphoribosyl-3'-dephosphocoenzyme A)-L-serine" EXACT RESID-alternate []
synonym	"OPRibdPCoASer" EXACT PSI-MOD-label []
synonym	"phosphoribosyl dephospho-coenzyme A" RELATED UniMod-description []
synonym	"PhosphoribosyldephosphoCoA" RELATED PSI-MS-label []
xref	DiffAvg: "881.63"
xref	DiffFormula: "C 26 H 42 N 7 O 19 P 3 S 1"
xref	DiffMono: "881.146903"
xref	Formula: "C 29 H 47 N 8 O 21 P 3 S 1"
xref	MassAvg: "968.71"
xref	MassMono: "968.178931"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.177. MOD:00177 omega-N-(ADP-ribosyl)-L-arginine

Table 179. Term [MOD:00177]
id	MOD:00177
name	omega-N-(ADP-ribosyl)-L-arginine
def	"A protein modification that effectively converts an L-argininine residue to omega-N-(ADP-ribosyl)-L-arginine." [DeltaMass:0, PubMed:15842200, PubMed:209022, PubMed:3090031, PubMed:3923473, PubMed:6582062, RESID:AA0168, UniMod:213#R]
comment	From DeltaMass: Average Mass: 541.
subset	PSI-MOD-slim
synonym	"(S)-2-amino-5-([imino([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]amino)methyl]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"ADP Ribose addition" RELATED UniMod-description []
synonym	"ADP-Ribosyl" RELATED PSI-MS-label []
synonym	"ADPRibArg" EXACT PSI-MOD-label []
synonym	"MOD_RES ADP-ribosylarginine" EXACT UniProt-feature []
synonym	"N(omega)-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-arginine" EXACT RESID-alternate []
synonym	"N(omega)-alpha-D-ribofuranosyl-L-arginine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
synonym	"N-(ADP-ribosyl)- (on Arginine)" EXACT DeltaMass-label []
synonym	"omega-N-(ADP-ribosyl)-L-arginine" EXACT RESID-name []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 21 H 33 N 9 O 14 P 2"
xref	MassAvg: "697.49"
xref	MassMono: "697.162220"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.178. MOD:00178 S-(ADP-ribosyl)-L-cysteine

Table 180. Term [MOD:00178]
id	MOD:00178
name	S-(ADP-ribosyl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(ADP-ribosyl)-L-cysteine." [DeltaMass:0, PubMed:15842200, PubMed:3863818, RESID:AA0169, UniMod:213#C]
comment	From DeltaMass: Average Mass: 541.
subset	PSI-MOD-slim
synonym	"®-2-amino-3-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"ADP Ribose addition" RELATED UniMod-description []
synonym	"ADP-Ribosyl" RELATED PSI-MS-label []
synonym	"ADPRibCys" EXACT PSI-MOD-label []
synonym	"MOD_RES ADP-ribosylcysteine" EXACT UniProt-feature []
synonym	"S-(ADP-ribosyl)- (on Cysteine)" EXACT DeltaMass-label []
synonym	"S-(ADP-ribosyl)-L-cysteine" EXACT RESID-name []
synonym	"S-alpha-D-ribofuranosyl-L-cysteine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
synonym	"S-L-cysteine alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2 S 0"
xref	DiffMono: "541.061109"
xref	Formula: "C 18 H 26 N 6 O 14 P 2 S 1"
xref	MassAvg: "644.44"
xref	MassMono: "644.070294"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.179. MOD:00179 L-glutamyl 5-glycerylphosphorylethanolamine

Table 181. Term [MOD:00179]
id	MOD:00179
name	L-glutamyl 5-glycerylphosphorylethanolamine
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl 5-glycerylphosphorylethanolamine." [PubMed:2511205, PubMed:2569467, PubMed:9662537, RESID:AA0170, UniMod:396#E]
comment	glycerylPE
subset	PSI-MOD-slim
synonym	"(S)-2-amino-5-[2-([([2,3-dihydroxypropyl]oxy)(hydroxy)phosphoryl]oxy)ethyl]amino-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"5-L-glutamyl glycerylphosphorylethanolamine" EXACT RESID-name []
synonym	"5GlyceroPEtAGlu" EXACT PSI-MOD-label []
synonym	"GlycerylPE" RELATED PSI-MS-label []
synonym	"glycerylphosphorylethanolamine" RELATED UniMod-description []
synonym	"L-glutamyl 5-glycerophosphoethanolamine" EXACT RESID-alternate []
synonym	"L-glutamyl 5-glycerophosphorylethanolamine" EXACT RESID-alternate []
synonym	"L-glutamyl 5-glycerylphosphorylethanolamine" EXACT RESID-alternate []
synonym	"MOD_RES 5-glutamyl glycerylphosphorylethanolamine" EXACT UniProt-feature []
xref	DiffAvg: "197.13"
xref	DiffFormula: "C 5 H 12 N 1 O 5 P 1"
xref	DiffMono: "197.045309"
xref	Formula: "C 10 H 19 N 2 O 8 P 1"
xref	MassAvg: "326.24"
xref	MassMono: "326.087902"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.180. MOD:00180 S-sulfo-L-cysteine

Table 182. Term [MOD:00180]
id	MOD:00180
name	S-sulfo-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-sulfo-L-cysteine." [PubMed:12876326, PubMed:14752058, PubMed:643076, RESID:AA0171, UniMod:40#C]
synonym	"(2R)-2-amino-3-(sulfosulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(sulfothio)propanoic acid" EXACT RESID-alternate []
synonym	"3-(sulfosulfanyl)-L-alanine" EXACT RESID-alternate []
synonym	"cysteine sulfate thioester" EXACT RESID-alternate []
synonym	"cysteine-S-sulfonic acid" EXACT RESID-alternate []
synonym	"O-Sulfonation" RELATED UniMod-description []
synonym	"S-sulfo-L-cysteine" EXACT RESID-name []
synonym	"S-sulfocysteine" EXACT PSI-MOD-alternate []
synonym	"S-sulfocysteine" EXACT RESID-alternate []
synonym	"SSulfCys" EXACT PSI-MOD-label []
synonym	"Sulfo" RELATED PSI-MS-label []
xref	DiffAvg: "80.06"
xref	DiffFormula: "C 0 H 0 N 0 O 3 S 1"
xref	DiffMono: "79.956815"
xref	Formula: "C 3 H 5 N 1 O 4 S 2"
xref	MassAvg: "183.20"
xref	MassMono: "182.966000"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00695 sulfated residue ! sulfated residue
is_a	MOD:00777 residues isobaric at 182.96-182.98 Da ! residues isobaric at 182.96-182.98 Da
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.181. MOD:00181 O4'-sulfo-L-tyrosine

Table 183. Term [MOD:00181]
id	MOD:00181
name	O4'-sulfo-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-sulfo-L-tyrosine." [DeltaMass:88, OMSSA:114, PubMed:10226369, PubMed:14752058, PubMed:2303439, PubMed:3778455, PubMed:3801003, RESID:AA0172, UniMod:40#Y]
comment	From DeltaMass: Average Mass: 80 Average Mass Change:80 PubMed:9624161.
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(4-sulfooxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-sulfate" EXACT RESID-alternate []
synonym	"MOD_RES Sulfotyrosine" EXACT UniProt-feature []
synonym	"O-Sulfonation" RELATED UniMod-description []
synonym	"O4'-sulfo-L-tyrosine" EXACT RESID-name []
synonym	"O4-sulfotyrosine" EXACT RESID-alternate []
synonym	"OSulfTyr" EXACT PSI-MOD-label []
synonym	"sulfationy" EXACT OMSSA-label []
synonym	"Sulfo" RELATED PSI-MS-label []
synonym	"Sulphation (of O of Tyrosine)" EXACT DeltaMass-label []
synonym	"tyrosine sulfate" EXACT RESID-alternate []
synonym	"tyrosine-O-sulfonic acid" EXACT RESID-alternate []
synonym	"tyrosine-O-sulphonic acid" EXACT RESID-alternate []
synonym	"Tyrosinyl Sulphate" EXACT DeltaMass-label []
xref	DiffAvg: "80.06"
xref	DiffFormula: "C 0 H 0 N 0 O 3 S 1"
xref	DiffMono: "79.956815"
xref	Formula: "C 9 H 9 N 1 O 5 S 1"
xref	MassAvg: "243.23"
xref	MassMono: "243.020143"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00695 sulfated residue ! sulfated residue
is_a	MOD:00774 residues isobaric at 243.02-243.03 Da ! residues isobaric at 243.02-243.03 Da
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.182. MOD:00182 L-bromohistidine

Table 184. Term [MOD:00182]
id	MOD:00182
name	L-bromohistidine
def	"A protein modification that effectively converts an L-histidine residue to L-bromohistidine." [PubMed:2076468, PubMed:9033387, RESID:AA0173, UniMod:340#H]
synonym	"Br1His" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
synonym	"L-bromohistidine" EXACT RESID-name []
synonym	"MOD_RES Bromohistidine" EXACT UniProt-feature []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 6 H 6 N 3 O 1"
xref	MassAvg: "216.04"
xref	MassMono: "214.969424"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01049 halogenated histidine ! halogenated histidine
is_a	MOD:01912 monobrominated residue ! monobrominated residue

2.183. MOD:00183 L-2'-bromophenylalanine

Table 185. Term [MOD:00183]
id	MOD:00183
name	L-2'-bromophenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to L-2'-bromophenylalanine." [DeltaMass:83, PubMed:2059627, PubMed:2076468, PubMed:9033387, RESID:AA0174]
comment	From DeltaMass: Average Mass: 78 Average Mass Change:78 References:Yoshino,K et.al. Biochemistry Vol. 30 pg 6203-9 (1991) Identifidation of a novel amino acid, o-bromo-L-phenylananine, in egg-associated peptides that activate spermatozoa.
synonym	"(S)-2-amino-3-(2-bromophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2’BrPhe" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
synonym	"L-2'-bromophenylalanine" EXACT RESID-name []
synonym	"L-o-bromination of Phe with 79Br" EXACT DeltaMass-label []
synonym	"o-bromophenylalanine" EXACT RESID-alternate []
synonym	"ortho-bromophenylalanine" EXACT RESID-alternate []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 9 H 8 N 1 O 1"
xref	MassAvg: "226.07"
xref	MassMono: "224.978926"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00972 monobrominated L-phenylalanine ! monobrominated L-phenylalanine

2.184. MOD:00184 L-3'-bromophenylalanine

Table 186. Term [MOD:00184]
id	MOD:00184
name	L-3'-bromophenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to L-3'-bromophenylalanine." [PubMed:2076468, PubMed:9033387, RESID:AA0175]
synonym	"(S)-2-amino-3-(3-bromophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3’BrPhe" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
synonym	"L-3'-bromophenylalanine" EXACT RESID-name []
synonym	"m-bromophenylalanine" EXACT RESID-alternate []
synonym	"meta-bromophenylalanine" EXACT RESID-alternate []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 9 H 8 N 1 O 1"
xref	MassAvg: "226.07"
xref	MassMono: "224.978926"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00972 monobrominated L-phenylalanine ! monobrominated L-phenylalanine

2.185. MOD:00185 L-4'-bromophenylalanine

Table 187. Term [MOD:00185]
id	MOD:00185
name	L-4'-bromophenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to L-4'-bromophenylalanine." [PubMed:2076468, PubMed:9033387, RESID:AA0176]
synonym	"(2S)-2-amino-3-(4-bromophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"4’BrPhe" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
synonym	"L-4'-bromophenylalanine" EXACT RESID-name []
synonym	"p-bromophenylalanine" EXACT RESID-alternate []
synonym	"para-bromophenylalanine" EXACT RESID-alternate []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 9 H 8 N 1 O 1"
xref	MassAvg: "226.07"
xref	MassMono: "224.978926"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00972 monobrominated L-phenylalanine ! monobrominated L-phenylalanine

2.186. MOD:00186 3',3'',5'-triiodo-L-thyronine

Table 188. Term [MOD:00186]
id	MOD:00186
name	3',3'',5'-triiodo-L-thyronine
def	"A protein modification that effectively substitutes an L-tyrosine residue with 3',3'',5'-triiodo-L-thyronine." [ChEBI:18258, DeltaMass:0, RESID:AA0177, UniMod:397]
comment	From DeltaMass: Average Mass: 470.
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid" EXACT RESID-systematic []
synonym	"3',3'',5'-triiodo-L-thyronine" EXACT RESID-name []
synonym	"3,3',5-triiodo-L-thyronine" EXACT RESID-alternate []
synonym	"3,5,3'-triiodo-L-thyronine" EXACT RESID-alternate []
synonym	"3,5,3'-Triiodothyronine (from Tyrosine)" EXACT DeltaMass-label []
synonym	"4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine" EXACT RESID-alternate []
synonym	"I3Thy" EXACT PSI-MOD-label []
synonym	"liothyronine" EXACT RESID-alternate []
synonym	"MOD_RES Triiodothyronine" EXACT UniProt-feature []
synonym	"O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine" EXACT RESID-alternate []
synonym	"T3" EXACT RESID-alternate []
synonym	"triiodo" RELATED UniMod-description []
synonym	"Triiodothyronine" RELATED PSI-MS-label []
xref	DiffAvg: "469.79"
xref	DiffFormula: "C 6 H 1 I 3 N 0 O 1"
xref	DiffMono: "469.716158"
xref	Formula: "C 15 H 10 I 3 N 1 O 3"
xref	MassAvg: "632.96"
xref	MassMono: "632.779486"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00502 triiodinated residue ! triiodinated residue
is_a	MOD:00998 iodinated tyrosine ! iodinated tyrosine

2.187. MOD:00187 L-thyroxine

Table 189. Term [MOD:00187]
id	MOD:00187
name	L-thyroxine
def	"A protein modification that effectively substitutes an L-tyrosine residue with L-thyroxine." [ChEBI:18332, PubMed:6704086, RESID:AA0178, UniMod:398]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid" EXACT RESID-systematic []
synonym	"3',3'',5',5''-tetraiodo-L-thyronine" EXACT RESID-alternate []
synonym	"3,3',5,5'-tetraiodo-L-thyronine" EXACT RESID-alternate []
synonym	"3,5,3',5'-tetraiodo-L-thyronine" EXACT RESID-alternate []
synonym	"4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine" EXACT RESID-alternate []
synonym	"I4Thy" EXACT PSI-MOD-label []
synonym	"L-thyroxine" EXACT RESID-name []
synonym	"MOD_RES Thyroxine" EXACT UniProt-feature []
synonym	"O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine" EXACT RESID-alternate []
synonym	"T4" EXACT RESID-alternate []
synonym	"tetraiodo" RELATED UniMod-description []
synonym	"Thyroxine" RELATED PSI-MS-label []
xref	DiffAvg: "595.68"
xref	DiffFormula: "C 6 H 0 I 4 N 0 O 1"
xref	DiffMono: "595.612805"
xref	Formula: "C 15 H 9 I 4 N 1 O 3"
xref	MassAvg: "758.86"
xref	MassMono: "758.676134"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00998 iodinated tyrosine ! iodinated tyrosine

2.188. MOD:00188 6'-bromo-L-tryptophan

Table 190. Term [MOD:00188]
id	MOD:00188
name	6'-bromo-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 6'-bromo-L-tryptophan." [PubMed:12118011, PubMed:9030520, PubMed:9033387, PubMed:9434739, RESID:AA0179, UniMod:340#W]
synonym	"(2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"6'-bromo-L-tryptophan" EXACT RESID-name []
synonym	"6'-BrTrp" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
synonym	"MOD_RES 6'-bromotryptophan" EXACT UniProt-feature []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 11 H 9 N 2 O 1"
xref	MassAvg: "265.11"
xref	MassMono: "263.989825"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01068 halogenated tryptophan ! halogenated tryptophan
is_a	MOD:01912 monobrominated residue ! monobrominated residue

2.189. MOD:00189 dehydroalanine (Ser)

Table 191. Term [MOD:00189]
id	MOD:00189
name	dehydroalanine (Ser)
def	"A protein modification that effectively converts an L-serine residue to dehydroalanine." [DeltaMass:0, OMSSA:140, OMSSA:164, OMSSA:96, PubMed:10220322, PubMed:1547888, PubMed:1815586, PubMed:2914619, PubMed:7947813, PubMed:8239649, RESID:AA0181#SER, UniMod:23#S]
subset	PSI-MOD-slim
synonym	"2,3-didehydroalanine" EXACT RESID-alternate []
synonym	"2-aminoacrylic acid" EXACT RESID-alternate []
synonym	"2-aminopropenoic acid" EXACT RESID-systematic []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"anhydroserine" EXACT RESID-alternate []
synonym	"beta-elim-s" EXACT OMSSA-label []
synonym	"Dehydrated" RELATED PSI-MS-label []
synonym	"dehydro" EXACT OMSSA-label []
synonym	"dehydroalanine" EXACT RESID-name []
synonym	"Dha" EXACT RESID-alternate []
synonym	"Dha(Ser)" EXACT PSI-MOD-label []
synonym	"MOD_RES 2,3-didehydroalanine (Ser)" EXACT UniProt-feature []
synonym	"phospholosss" EXACT OMSSA-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00416 phosphorylation of an hydroxyl amino acid with prompt loss of phosphate ! phosphorylation of an hydroxyl amino acid with prompt loss of phosphate
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01168 dehydroalanine ! dehydroalanine

2.190. MOD:00190 dehydrobutyrine (Thr)

Table 192. Term [MOD:00190]
id	MOD:00190
name	dehydrobutyrine (Thr)
def	"A protein modification that effectively converts an L-threonine residue to dehydrobutyrine." [DeltaMass:0, OMSSA:141, OMSSA:164, OMSSA:97, PubMed:1547888, PubMed:3769923, RESID:AA0182, UniMod:23#T]
subset	PSI-MOD-slim
synonym	"(2Z)-2-aminobut-2-enoic acid" EXACT RESID-systematic []
synonym	"(Z)-2-amino-2-butenoic acid" EXACT RESID-alternate []
synonym	"(Z)-2-aminobutenoic acid" EXACT RESID-alternate []
synonym	"(Z)-dehydrobutyrine" EXACT RESID-name []
synonym	"2,3-didehydrobutyrine" EXACT RESID-alternate []
synonym	"3-methyldehydroalanine" EXACT RESID-alternate []
synonym	"alpha,beta-dehydroaminobutyric acid" EXACT RESID-alternate []
synonym	"anhydrothreonine" EXACT RESID-alternate []
synonym	"beta-elim-t" EXACT OMSSA-label []
synonym	"Dehydrated" RELATED PSI-MS-label []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"dehydro" EXACT OMSSA-label []
synonym	"Dehydroamino butyric acid" EXACT DeltaMass-label []
synonym	"Dhb" EXACT RESID-alternate []
synonym	"Dhb(Thr)" EXACT PSI-MOD-label []
synonym	"methyl-dehydroalanine" EXACT RESID-alternate []
synonym	"MOD_RES (Z)-2,3-didehydrobutyrine" EXACT UniProt-feature []
synonym	"phospholosst" EXACT OMSSA-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00416 phosphorylation of an hydroxyl amino acid with prompt loss of phosphate ! phosphorylation of an hydroxyl amino acid with prompt loss of phosphate
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01703 dehydrobutyrine ! dehydrobutyrine

2.191. MOD:00191 (Z)-2,3-didehydrotyrosine

Table 193. Term [MOD:00191]
id	MOD:00191
name	(Z)-2,3-didehydrotyrosine
def	"A protein modification that effectively converts L-tyrosine to (Z)-2,3-didehydrotyrosine." [PubMed:1347277, PubMed:9631087, RESID:AA0183]
comment	incidental to RESID:AA0184; incidental to RESID:AA0187; incidental to RESID:AA0188; incidental to RESID:AA0189; incidental to RESID:AA0378; incidental to RESID:AA0379; incidental to RESID:AA0380; incidental to RESID:AA0381
subset	PSI-MOD-slim
synonym	"(2Z)-2-amino-3-(4-hydroxyphenyl)prop-2-enoic acid" EXACT RESID-systematic []
synonym	"(Z)-2,3-didehydrogenated tyrosine" EXACT PSI-MOD-alternate []
synonym	"(Z)-2,3-didehydrotyrosine" EXACT RESID-name []
synonym	"2-amino-3-oxo-butanoic_acid" RELATED UniMod-description []
synonym	"amino-(para-hydroxybenzylidenyl)acetic acid" EXACT RESID-alternate []
synonym	"cis-dehydrotyrosine" EXACT RESID-alternate []
synonym	"Didehydro" RELATED PSI-MS-label []
synonym	"green fluorescent protein chromophore" EXACT RESID-alternate []
synonym	"MOD_RES (Z)-2,3-didehydrotyrosine" EXACT UniProt-feature []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"red fluorescent protein chromophore" EXACT RESID-alternate []
synonym	"Z-dHTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 9 H 7 N 1 O 2"
xref	MassAvg: "161.16"
xref	MassMono: "161.047678"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00706 dehydrogenated tyrosine ! dehydrogenated tyrosine

2.192. MOD:00192 L-serine 5-imidazolinone glycine

Table 194. Term [MOD:00192]
id	MOD:00192
name	L-serine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-serine residue and a glycine residue to form L-serine 5-imidazolinone glycine." [ChEBI:21393, PubMed:1347277, PubMed:9631087, RESID:AA0184]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[(1R)-1-amino-2-hydroxyethyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2-[1-amino-2-hydroxyethyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"CROSSLNK 5-imidazolinone (Ser-Gly)" EXACT UniProt-feature []
synonym	"green fluorescent protein chromophore" EXACT RESID-alternate []
synonym	"L-serine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"seryl-5-imidazolinone glycine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 6 N 2 O 2"
xref	MassAvg: "126.11"
xref	MassMono: "126.042927"
xref	Origin: "G, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.193. MOD:00193 L-3-oxoalanine (Cys)

Table 195. Term [MOD:00193]
id	MOD:00193
name	L-3-oxoalanine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to L-oxoalanine." [DeltaMass:350, PubMed:14563551, PubMed:7628016, PubMed:8681943, PubMed:9478923, RESID:AA0185#CYS, UniMod:402#C]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-oxopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-oxopropionic acid" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine" RELATED RESID-misnomer []
synonym	"L-3-oxoalanine" EXACT RESID-name []
synonym	"L-amino-malonic acid semialdehyde" EXACT RESID-alternate []
synonym	"L-aminomalonaldehydic acid" EXACT RESID-alternate []
synonym	"L-serinesemialdehyde" RELATED RESID-misnomer []
synonym	"MOD_RES 3-oxoalanine (Cys)" EXACT UniProt-feature []
synonym	"Oxala(Cys)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.08"
xref	DiffFormula: "C 0 H -2 N 0 O 1 S -1"
xref	DiffMono: "-17.992806"
xref	Formula: "C 3 H 3 N 1 O 2"
xref	MassAvg: "85.06"
xref	MassMono: "85.016378"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01169 L-3-oxoalanine ! L-3-oxoalanine

2.194. MOD:00194 lactic acid

Table 196. Term [MOD:00194]
id	MOD:00194
name	lactic acid
def	"A protein modification that effectively converts an L-serine residue to an amino-terminal lactic acid." [PubMed:7607233, RESID:AA0186, UniMod:403#S]
synonym	"(2R)-2-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-hydroxypropionic acid" EXACT RESID-alternate []
synonym	"alpha-hydroxypropionic acid" EXACT RESID-alternate []
synonym	"Lac(Ser)" EXACT PSI-MOD-label []
synonym	"lactic acid" EXACT RESID-name []
synonym	"lactic acid from N-term Ser" RELATED UniMod-description []
synonym	"MOD_RES Lactic acid" EXACT UniProt-feature []
synonym	"Ser→LacticAcid" RELATED PSI-MS-label []
xref	DiffAvg: "-15.02"
xref	DiffFormula: "C 0 H -1 N -1 O 0"
xref	DiffMono: "-15.010899"
xref	Formula: "C 3 H 5 O 2"
xref	MassAvg: "73.07"
xref	MassMono: "73.028954"
xref	Origin: "S"
xref	TermSpec: "N-term"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.195. MOD:00195 L-alanine 5-imidazolinone glycine

Table 197. Term [MOD:00195]
id	MOD:00195
name	L-alanine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-alanine residue and a glycine residue to form L-alanine 5-imidazolinone glycine." [PubMed:10220322, RESID:AA0187]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0181; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[(1S)-1-aminoethyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2-[1-aminoethyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"4-methylidene-imidazole-5-one active site" EXACT RESID-alternate []
synonym	"alanyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"CROSSLNK 5-imidazolinone (Ala-Gly)" EXACT UniProt-feature []
synonym	"L-alanine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"XLNK-1Ala-NGly(Imidazole)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 6 N 2 O 1"
xref	MassAvg: "110.12"
xref	MassMono: "110.048013"
xref	Origin: "A, G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.196. MOD:00196 L-cysteine 5-imidazolinone glycine

Table 198. Term [MOD:00196]
id	MOD:00196
name	L-cysteine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue to form L-cysteine 5-imidazolinone glycine." [PubMed:1537807, RESID:AA0188]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0181; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[(1R)-1-amino-2-sulfanylethyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2-[1-amino-2-sulfanylethyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"CROSSLNK 5-imidazolinone (Cys-Gly)" EXACT UniProt-feature []
synonym	"cysteinyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"L-cysteine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"XLNK-1Cys-NGly(Imidazole)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 6 N 2 O 1 S 1"
xref	MassAvg: "142.18"
xref	MassMono: "142.020084"
xref	Origin: "C, G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.197. MOD:00197 2-imino-glutamine 5-imidazolinone glycine

Table 199. Term [MOD:00197]
id	MOD:00197
name	2-imino-glutamine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-glutamine residue and a glycine residue to form 2-imino-glutamine 5-imidazolinone glycine." [PubMed:11050230, PubMed:11209050, RESID:AA0189]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"2,N-didehydroglutaminyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"2-(3-carbamoyl-1-imino-propyl)-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"2-imino-glutamine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"[2-(3-carbamoyl-1-imino-propyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid" EXACT RESID-alternate []
synonym	"[2-(4-amino-4-oxobutanimidoyl)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid" EXACT RESID-systematic []
synonym	"CROSSLNK 2-iminomethyl-5-imidazolinone (Gln-Gly)" EXACT UniProt-feature []
synonym	"fluorescent protein FP583 chromophore" EXACT RESID-alternate []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"red fluorescent protein chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 7 N 3 O 2"
xref	MassAvg: "165.15"
xref	MassMono: "165.053826"
xref	Origin: "G, Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.198. MOD:00198 D-alanine (Ala)

Table 200. Term [MOD:00198]
id	MOD:00198
name	D-alanine (Ala)
def	"A protein modification that effectively converts an L-alanine residue to D-alanine." [PubMed:15023056, PubMed:7287302, PubMed:7961627, RESID:AA0191#ALA]
synonym	"®-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"D-Ala(Ala)" EXACT PSI-MOD-label []
synonym	"D-alanine" EXACT RESID-name []
synonym	"MOD_RES D-alanine (Ala)" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00570 residues isobaric at 71.037114 Da ! residues isobaric at 71.037114 Da
is_a	MOD:00862 D-alanine ! D-alanine
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.199. MOD:00199 D-allo-isoleucine

Table 201. Term [MOD:00199]
id	MOD:00199
name	D-allo-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a D-allo-isoleucine." [ChEBI:30007, PubMed:8223491, RESID:AA0192]
synonym	"(2R,3S)-2-amino-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-methylpentanoic acid" EXACT RESID-alternate []
synonym	"3-methyl-norvaline" EXACT RESID-alternate []
synonym	"allo-D-isoleucine" EXACT RESID-alternate []
synonym	"alpha-amino-beta-methylvaleric acid" EXACT RESID-alternate []
synonym	"D-allo-isoleucine" EXACT RESID-name []
synonym	"D-Ile" EXACT PSI-MOD-label []
synonym	"D-threo-isoleucine" EXACT RESID-alternate []
synonym	"MOD_RES D-allo-isoleucine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00306 residues isobaric at 113.084064 Da ! residues isobaric at 113.084064 Da
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue

2.200. MOD:00200 D-methionine

Table 202. Term [MOD:00200]
id	MOD:00200
name	D-methionine
def	"A protein modification that effectively converts an L-methionine residue to D-methionine." [ChEBI:29984, PubMed:16033333, PubMed:2542051, RESID:AA0193]
synonym	"(2R)-2-amino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-amino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-(methylthio)butyric acid" EXACT RESID-alternate []
synonym	"D-Met" EXACT PSI-MOD-label []
synonym	"D-methionine" EXACT RESID-name []
synonym	"MOD_RES D-methionine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.040485"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.201. MOD:00201 D-phenylalanine

Table 203. Term [MOD:00201]
id	MOD:00201
name	D-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to D-phenylalanine." [ChEBI:29996, PubMed:1548227, PubMed:1644179, PubMed:2597281, RESID:AA0194]
synonym	"®-2-amino-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"D-Phe" EXACT PSI-MOD-label []
synonym	"D-phenylalanine" EXACT RESID-name []
synonym	"MOD_RES D-phenylalanine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 9 H 9 N 1 O 1"
xref	MassAvg: "147.18"
xref	MassMono: "147.068414"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.202. MOD:00202 D-serine (Ser)

Table 204. Term [MOD:00202]
id	MOD:00202
name	D-serine (Ser)
def	"A protein modification that effectively converts an L-serine residue to D-serine." [PubMed:7973665, RESID:AA0195#SER]
synonym	"®-2-amino-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"D-Ser(Ser)" EXACT PSI-MOD-label []
synonym	"D-serine" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 3 H 5 N 1 O 2"
xref	MassAvg: "87.08"
xref	MassMono: "87.032028"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00891 D-serine ! D-serine
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.203. MOD:00203 D-asparagine

Table 205. Term [MOD:00203]
id	MOD:00203
name	D-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to D-asparagine." [ChEBI:29957, PubMed:1859408, RESID:AA0196]
synonym	"®-2-amino-4-butanediamic acid" EXACT RESID-systematic []
synonym	"D-alpha-aminosuccinamic acid" EXACT RESID-alternate []
synonym	"D-Asn" EXACT PSI-MOD-label []
synonym	"D-asparagine" EXACT RESID-name []
synonym	"D-aspartic acid beta-amide" EXACT RESID-alternate []
synonym	"MOD_RES D-asparagine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 6 N 2 O 2"
xref	MassAvg: "114.10"
xref	MassMono: "114.042927"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.204. MOD:00204 D-leucine

Table 206. Term [MOD:00204]
id	MOD:00204
name	D-leucine
def	"A protein modification that effectively converts an L-leucine residue to D-leucine." [ChEBI:30005, PubMed:10461743, PubMed:12135762, PubMed:1358533, PubMed:1548227, RESID:AA0197]
synonym	"(2R)-2-amino-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"alpha-aminoisocaproic acid" EXACT RESID-alternate []
synonym	"D-Leu" EXACT PSI-MOD-label []
synonym	"D-leucine" EXACT RESID-name []
synonym	"MOD_RES D-leucine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00306 residues isobaric at 113.084064 Da ! residues isobaric at 113.084064 Da
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.205. MOD:00205 D-tryptophan

Table 207. Term [MOD:00205]
id	MOD:00205
name	D-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to D-tryptophan." [ChEBI:29955, PubMed:8910408, RESID:AA0198]
synonym	"®-2-amino-3-(1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"alpha-amino-beta-(3-indolyl)propionoic acid" EXACT RESID-alternate []
synonym	"D-Trp" EXACT PSI-MOD-label []
synonym	"D-tryptophan" EXACT RESID-name []
synonym	"MOD_RES D-tryptophan" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 11 H 10 N 2 O 1"
xref	MassAvg: "186.21"
xref	MassMono: "186.079313"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.206. MOD:00206 L-isoglutamyl-polyglycine

Table 208. Term [MOD:00206]
id	MOD:00206
name	L-isoglutamyl-polyglycine
def	"A protein modification that effectively converts an L-glutamic acid residue to L-isoglutamyl-polyglycine." [ChEBI:21343, PubMed:10074368, PubMed:16368691, PubMed:7992051, RESID:AA0201]
synonym	"gamma-glutamylpolyglycine" EXACT RESID-alternate []
synonym	"L-isoglutamyl-polyglycine" EXACT RESID-name []
synonym	"MOD_RES 5-glutamyl polyglycine" EXACT UniProt-feature []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "C 7 H 10 N 2 O 4"
xref	MassAvg: "186.17"
xref	MassMono: "186.064057"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.207. MOD:00207 L-isoglutamyl-polyglutamic acid

Table 209. Term [MOD:00207]
id	MOD:00207
name	L-isoglutamyl-polyglutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to isoglutamyl-polyglutamic acid, forming an isopeptide bond with a polyglutamic acid." [PubMed:10747868, PubMed:1680872, RESID:AA0202]
synonym	"gamma-glutamylpolyglutamic acid" EXACT RESID-alternate []
synonym	"L-isoglutamyl-polyglutamic acid" EXACT RESID-name []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 10 H 14 N 2 O 6"
xref	MassAvg: "258.23"
xref	MassMono: "258.085186"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.208. MOD:00208 O4'-(phospho-5'-adenosine)-L-tyrosine

Table 210. Term [MOD:00208]
id	MOD:00208
name	O4'-(phospho-5'-adenosine)-L-tyrosine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and 5'-phosphoadenosine through a phosphodiester bond to form O4'-(phospho-5'-adenosine)-L-tyrosine." [DeltaMass:0, PubMed:5543675, RESID:AA0203, UniMod:405#Y]
comment	From DeltaMass: Average Mass: 329.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-[4-(5'-adenosine phosphonoxy)phenyl]propanoic acid" EXACT RESID-systematic []
synonym	"5'-adenylic-O-tyrosine" EXACT RESID-alternate []
synonym	"AMP binding site" RELATED UniMod-description []
synonym	"hydrogen 5'-adenylate tyrosine ester" EXACT RESID-alternate []
synonym	"MOD_RES O-AMP-tyrosine" EXACT UniProt-feature []
synonym	"O-5'-Adenosylation ( of Tyrosine)" EXACT DeltaMass-label []
synonym	"O4'-(phospho-5'-adenosine)-L-tyrosine" EXACT RESID-name []
synonym	"O4'-L-tyrosine 5'-adenosine phosphodiester" EXACT RESID-alternate []
synonym	"OAMPTyr" EXACT PSI-MOD-label []
synonym	"Phosphoadenosine" RELATED PSI-MS-label []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "C 19 H 21 N 6 O 8 P 1"
xref	MassAvg: "492.38"
xref	MassMono: "492.115848"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01165 adenylated residue ! adenylated residue

2.209. MOD:00209 S-(2-aminovinyl)-D-cysteine (Cys-Ser)

Table 211. Term [MOD:00209]
id	MOD:00209
name	S-(2-aminovinyl)-D-cysteine (Cys-Ser)
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form S-(2-aminovinyl)-D-cysteine." [PubMed:3181159, PubMed:3769923, RESID:AA0204#SER]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-([(Z)-2-aminoethenyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(S,Z)-S-(2-aminovinyl)cysteine" EXACT RESID-alternate []
synonym	"CROSSLNK S-(2-aminovinyl)-D-cysteine (Ser-Cys)" EXACT UniProt-feature []
synonym	"S-(2-aminovinyl)-D-cysteine" EXACT RESID-name []
synonym	"XLNK-(D)SCys-VinAm" EXACT PSI-MOD-label []
xref	DiffAvg: "-64.04"
xref	DiffFormula: "C -1 H -4 N 0 O -3 S 0"
xref	DiffMono: "-64.016044"
xref	Formula: "C 5 H 7 N 2 O 1 S 1"
xref	MassAvg: "143.18"
xref	MassMono: "143.027909"
xref	Origin: "C, S"
xref	TermSpec: "C-term"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01850 S-(2-aminovinyl)-D-cysteine ! S-(2-aminovinyl)-D-cysteine

2.210. MOD:00210 L-cysteine sulfenic acid

Table 212. Term [MOD:00210]
id	MOD:00210
name	L-cysteine sulfenic acid
def	"A protein modification that effectively monooxygenates an L-cysteine residue to L-cysteine sulfenic acid." [DeltaMass:41, OMSSA:193, PubMed:10964927, PubMed:2501303, PubMed:8756456, PubMed:9214307, PubMed:9586994, PubMed:9587003, RESID:AA0205, UniMod:35#C]
comment	From DeltaMass: Average Mass: 16 Average Mass Change:16 Notes:Green et al. in J. B. C. 270, 18209-18211 (1995) quote Kim and Raines in Eur. J. Biochem. 224, 109-114 (1994). Kim and Raines using ESI-MS and sulfhydryl group titration found that bovine seminal ribonuclease contains a single oxidized sulfhydryl group, which cannot participate in a disulfide bond. This form of cysteine is called sulfenic acid (-SOH).
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-(hydroxysulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(2R)-2-amino-3-(oxido-lambda(4)-sulfanyl)propanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-2-carboxyethanesulfenic acid" EXACT RESID-alternate []
synonym	"2-amino-3-sulfinylpropanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"3-sulfenoalanine" EXACT RESID-alternate []
synonym	"ACT_SITE Cysteine sulfenic acid (-SOH) intermediate" EXACT UniProt-feature []
synonym	"CysOH" EXACT PSI-MOD-label []
synonym	"cysteine S-oxide [tautomer]" EXACT RESID-alternate []
synonym	"cysteine sulfoxide [tautomer]" EXACT RESID-alternate []
synonym	"cysteine sulphenic acid" EXACT RESID-alternate []
synonym	"L-cysteine sulfenic acid" EXACT RESID-name []
synonym	"mod193" EXACT OMSSA-label []
synonym	"MOD_RES Cysteine sulfenic acid (-SOH)" EXACT UniProt-feature []
synonym	"Oxidation" RELATED PSI-MS-label []
synonym	"S-hydroxycysteine" EXACT RESID-alternate []
synonym	"S-oxocysteine [tautomer]" EXACT RESID-alternate []
synonym	"S-oxycysteine [tautomer]" EXACT RESID-alternate []
synonym	"Sulfenic Acid (from Cysteine)" EXACT DeltaMass-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S 0"
xref	DiffMono: "15.994915"
xref	Formula: "C 3 H 5 N 1 O 2 S 1"
xref	MassAvg: "119.14"
xref	MassMono: "119.004099"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01854 sulfur monooxygenated residue ! sulfur monooxygenated residue

2.211. MOD:00211 S-(glycyl)-L-cysteine (Cys-Gly)

Table 213. Term [MOD:00211]
id	MOD:00211
name	S-(glycyl)-L-cysteine (Cys-Gly)
def	"A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine." [ChEBI:22050, PubMed:3306404, RESID:AA0206]
comment	Cross-link 2. For the modification of a C-terminal glycine by formation of a thioester bond with free L-cycteine see MOD:01777 [JSG].
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-[(aminoacetyl)sulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"1-(cystein-S-yl)-glycinate" EXACT RESID-alternate []
synonym	"ACT_SITE Glycyl thioester intermediate" EXACT UniProt-feature []
synonym	"glycine cysteine thioester" EXACT RESID-alternate []
synonym	"S-(2-amino-1-oxoethyl)cysteine" EXACT RESID-alternate []
synonym	"S-(glycyl)-L-cysteine" EXACT RESID-name []
synonym	"XLNK-SCys-1Gly" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 7 N 2 O 2 S 1"
xref	MassAvg: "159.18"
xref	MassMono: "159.022823"
xref	Origin: "C, G"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.212. MOD:00212 S-4-hydroxycinnamyl-L-cysteine

Table 214. Term [MOD:00212]
id	MOD:00212
name	S-4-hydroxycinnamyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-4-hydroxycinnamyl-L-cysteine." [PubMed:7947803, PubMed:7981196, RESID:AA0207, UniMod:407]
synonym	"(2R)-2-amino-3-([(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"cinnamate cysteine thioester" EXACT RESID-alternate []
synonym	"Hydroxycinnamyl" RELATED PSI-MS-label []
synonym	"hydroxycinnamyl" RELATED UniMod-description []
synonym	"MOD_RES S-(4-hydroxycinnamyl)cysteine" EXACT UniProt-feature []
synonym	"S-4-hydroxycinnamyl-L-cysteine" EXACT RESID-name []
synonym	"S-para-coumaryl-L-cysteine" EXACT RESID-alternate []
xref	DiffAvg: "146.14"
xref	DiffFormula: "C 9 H 6 N 0 O 2 S 0"
xref	DiffMono: "146.036779"
xref	Formula: "C 12 H 11 N 1 O 3 S 1"
xref	MassAvg: "249.28"
xref	MassMono: "249.045964"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.213. MOD:00213 chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

Table 215. Term [MOD:00213]
id	MOD:00213
name	chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine
def	"A protein modification that effectively cross-links an L-serine residue to the polymer chondroitin sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide." [PubMed:1794445, PubMed:1898736, PubMed:3472204, RESID:AA0208]
synonym	"chondroitin 4-sulfate (chondroitin sulfate A)" EXACT RESID-alternate []
synonym	"chondroitin 6-sulfate (chondroitin sulfate C)" EXACT RESID-alternate []
synonym	"chondroitin sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT RESID-name []
synonym	"poly[beta-1,4-D-glucopyranuronosyl-beta-1,3-(2-acetamido-2-deoxy-4-sulfate-D-galactosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine; poly[beta-1,4-D-glucopyranuronosyl-beta-1,3-(2-acetamido-2-deoxy-6-sulfate D-galactosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine" EXACT RESID-systematic []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 3 H 4 N 1 O 2"
xref	MassAvg: "86.07"
xref	MassMono: "86.024203"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.214. MOD:00214 dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

Table 216. Term [MOD:00214]
id	MOD:00214
name	dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine
def	"A protein modification that effectively cross-links an L-serine residue to the polymer dermatan 4-sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide." [PubMed:2914936, PubMed:3472204, RESID:AA0209]
synonym	"beta-heparin" EXACT RESID-alternate []
synonym	"chondroitin sulfate B" EXACT RESID-alternate []
synonym	"dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT RESID-name []
synonym	"poly[beta-1,4-L-idopyranuronosyl-alpha-1,3-(2-acetamido-2-deoxy-4-sulfate D-galactosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine" EXACT RESID-systematic []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 3 H 4 N 1 O 2"
xref	MassAvg: "86.07"
xref	MassMono: "86.024203"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.215. MOD:00215 heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

Table 217. Term [MOD:00215]
id	MOD:00215
name	heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine
def	"A protein modification that effectively cross-links an L-serine residue to the polymer heparan sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide." [PubMed:3472204, RESID:AA0210]
synonym	"heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine" EXACT RESID-name []
synonym	"heparin" EXACT RESID-alternate []
synonym	"heparitin sulfate" EXACT RESID-alternate []
synonym	"poly[alpha-1,4-(2-sulfate D-glucopyranuronosyl)-beta-1,4-(2-sulfamino-2-deoxy-6-sulfate D-glucosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine" EXACT RESID-systematic []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 3 H 4 N 1 O 2"
xref	MassAvg: "86.07"
xref	MassMono: "86.024203"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.216. MOD:00216 N6-formyl-L-lysine

Table 218. Term [MOD:00216]
id	MOD:00216
name	N6-formyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-formyl-L-lysine." [OMSSA:43, PubMed:15799070, RESID:AA0211, UniMod:122#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(formylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"epsilon-formyllysine" EXACT RESID-alternate []
synonym	"Formyl" RELATED PSI-MS-label []
synonym	"Formylation" RELATED UniMod-description []
synonym	"formylk" EXACT OMSSA-label []
synonym	"MOD_RES N6-formyllysine" EXACT UniProt-feature []
synonym	"N(zeta)-formyllysine" EXACT RESID-alternate []
synonym	"N6-formyl-L-lysine" EXACT RESID-name []
synonym	"N6-formylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6FoLys" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 7 H 12 N 2 O 2"
xref	MassAvg: "156.19"
xref	MassMono: "156.089878"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.217. MOD:00217 O4-arabinosyl-L-hydroxyproline

Table 219. Term [MOD:00217]
id	MOD:00217
name	O4-arabinosyl-L-hydroxyproline
def	"A protein modification that effectively converts an L-proline residue to O4-arabinosyl-L-hydroxyproline." [DeltaMass:0, PubMed:666730, PubMed:7852316, RESID:AA0212, UniMod:408]
comment	secondary to RESID:AA0030; From DeltaMass: Average Mass: 147.
subset	PSI-MOD-slim
synonym	"(2S,4R)-4-(beta-L-arabinofuranosyloxy)pyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"4-(beta-L-arabinofuranosyloxy)proline" EXACT RESID-alternate []
synonym	"4-Glycosyloxy- (pentosyl,C5) (of Proline)" EXACT DeltaMass-label []
synonym	"beta-arabinofuranosyl-4-hydroxyproline" EXACT RESID-alternate []
synonym	"Glycosyl" RELATED PSI-MS-label []
synonym	"glycosyl-L-hydroxyproline" RELATED UniMod-description []
synonym	"O4-arabinosyl-L-hydroxyproline" EXACT RESID-name []
synonym	"O4-glycosyl-hydroxyproline" EXACT RESID-alternate []
synonym	"OAra4HyPro" EXACT PSI-MOD-label []
xref	DiffAvg: "148.11"
xref	DiffFormula: "C 5 H 8 N 0 O 5"
xref	DiffMono: "148.037173"
xref	Formula: "C 10 H 15 N 1 O 6"
xref	MassAvg: "245.23"
xref	MassMono: "245.089937"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.218. MOD:00218 O-(phospho-5'-RNA)-L-serine

Table 220. Term [MOD:00218]
id	MOD:00218
name	O-(phospho-5'-RNA)-L-serine
def	"A protein modification that effectively crosslinks an L-serine residue and the 5'-end of RNA through a phosphodiester to form O4'-(phospho-5'-RNA)-L-serine." [PubMed:1705009, RESID:AA0213]
synonym	"(S)-2-amino-3-(5'-ribonucleic acid phosphonoxy)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES O-(5'-phospho-RNA)-serine" EXACT UniProt-feature []
synonym	"O-(phospho-5'-RNA)-L-serine" EXACT RESID-name []
synonym	"O3-(phospho-5'-RNA)-L-serine" EXACT RESID-alternate []
synonym	"O3-L-serine 5'-RNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "78.97"
xref	DiffFormula: "C 0 H 0 N 0 O 3 P 1"
xref	DiffMono: "78.958505"
xref	Formula: "C 3 H 5 N 1 O 5 P 1"
xref	MassAvg: "166.05"
xref	MassMono: "165.990534"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00751 ribonucleic acid linked residue ! ribonucleic acid linked residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.219. MOD:00219 L-citrulline

Table 221. Term [MOD:00219]
id	MOD:00219
name	L-citrulline
def	"A protein modification that effectively converts an L-arginine residue to L-citrulline." [DeltaMass:0, OMSSA:33, PubMed:2466844, RESID:AA0214, UniMod:7#R]
comment	This modification is not the result of deamidation, instead the guanidino group is replaced with an ureido group.
subset	PSI-MOD-slim
synonym	"(S)-2-amino-5-(carbamoylamino)pentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-(aminocarbonyl)aminopentanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-delta-ureidovaleric acid" EXACT RESID-alternate []
synonym	"Cit" EXACT PSI-MOD-label []
synonym	"citrullinationr" EXACT OMSSA-label []
synonym	"Citrulline" EXACT DeltaMass-label []
synonym	"Deamidated" RELATED PSI-MS-label []
synonym	"Deamidated" RELATED UniMod-interim []
synonym	"Deamidation" RELATED UniMod-description []
synonym	"delta-ureidonorvaline" EXACT RESID-alternate []
synonym	"L-citrulline" EXACT RESID-name []
synonym	"MOD_RES Citrulline" EXACT UniProt-feature []
synonym	"N5-(aminocarbonyl)ornithine" EXACT RESID-alternate []
synonym	"N5-carbamoylornithine" EXACT RESID-alternate []
synonym	"N5-carbamylornithine" EXACT RESID-alternate []
xref	DiffAvg: "0.98"
xref	DiffFormula: "C 0 H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 6 H 11 N 3 O 2"
xref	MassAvg: "157.17"
xref	MassMono: "157.085127"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.220. MOD:00220 4-hydroxy-L-arginine

Table 222. Term [MOD:00220]
id	MOD:00220
name	4-hydroxy-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to a 4-hydroxy-L-arginine." [PubMed:10966817, PubMed:7650037, RESID:AA0215]
synonym	"(2S,4Xi)-2-amino-5-[(diaminomethylidene)amino]-4-hydroxypentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-(carbamimidamido)-4-hydroxypentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-[(aminoiminomethyl)amino]-4-hydroxypentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-guanidino-4-hydroxypentanoic acid" EXACT RESID-alternate []
synonym	"4-hydroxy-L-arginine" EXACT RESID-name []
synonym	"4-hydroxylated L-arginine" EXACT PSI-MOD-alternate []
synonym	"4HyArg" EXACT PSI-MOD-label []
synonym	"C(gamma)-hydroxyarginine" EXACT RESID-alternate []
synonym	"gamma-hydroxyarginine" EXACT RESID-alternate []
synonym	"MOD_RES 4-hydroxyarginine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 4 O 2"
xref	MassAvg: "172.19"
xref	MassMono: "172.096026"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00682 hydroxylated arginine ! hydroxylated arginine

2.221. MOD:00221 N-(L-isoaspartyl)-L-cysteine

Table 223. Term [MOD:00221]
id	MOD:00221
name	N-(L-isoaspartyl)-L-cysteine
def	"A protein modification that effectively crosslinks L-aspartic acid and L-cysteine residues via an isopeptide bond to form N-(L-isoaspartyl)-L-cysteine." [PubMed:8286361, RESID:AA0216]
comment	Cross-link 2.
synonym	"(S)-2-amino-4-(®-1-carboxy-2-sulfanylethyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-(3-amino-3-carboxypropanoyl)amino-3-mercaptopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-N4-(1-carboxy-2-mercaptoethyl)butanediamic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl cysteine isopeptide (Cys-Asn)" EXACT UniProt-feature []
synonym	"N-(L-isoaspartyl)-L-cysteine" EXACT RESID-name []
synonym	"N-beta-aspartylcysteine" EXACT RESID-alternate []
synonym	"N-isoaspartyl cysteine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0 S 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 7 H 9 N 2 O 3 S 1"
xref	MassAvg: "201.22"
xref	MassMono: "201.033388"
xref	Origin: "C, N"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.222. MOD:00222 2'-alpha-mannosyl-L-tryptophan

Table 224. Term [MOD:00222]
id	MOD:00222
name	2'-alpha-mannosyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 2'-alpha-mannosyl-L-tryptophan." [PubMed:15279557, PubMed:7547911, PubMed:7947762, RESID:AA0217, UniMod:41#W]
synonym	"(2S)-2-amino-3-(2-beta-D-mannopyranosyl-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2'-mannosyl-L-tryptophan" EXACT RESID-name []
synonym	"2'-tryptophan C-mannoside" EXACT RESID-alternate []
synonym	"C2’ManTrp" EXACT PSI-MOD-label []
synonym	"CARBOHYD C-linked (Man)" EXACT UniProt-feature []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 17 H 20 N 2 O 6"
xref	MassAvg: "348.36"
xref	MassMono: "348.132136"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00421 C-glycosylated residue ! C-glycosylated residue
is_a	MOD:00595 mannosylated residue ! mannosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.223. MOD:00223 N6-mureinyl-L-lysine

Table 225. Term [MOD:00223]
id	MOD:00223
name	N6-mureinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-mureinyl-L-lysine." [PubMed:4261992, RESID:AA0218]
synonym	"MOD_RES N6-murein peptidoglycan lysine" EXACT UniProt-feature []
synonym	"N6-[(2R,6S)-2-(N-(N-mureinyl-®-alanyl)-(S)-glutamyl)amino-6-amino-6-carboxy-1-oxohex-1-yl]lysine" EXACT RESID-alternate []
synonym	"N6-mureinyl-L-lysine" EXACT RESID-name []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 6 H 11 N 2 O 1"
xref	MassAvg: "127.17"
xref	MassMono: "127.087138"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01159 peptidoglycanated residue ! peptidoglycanated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.224. MOD:00224 1-chondroitin sulfate-L-aspartic acid ester

Table 226. Term [MOD:00224]
id	MOD:00224
name	1-chondroitin sulfate-L-aspartic acid ester
def	"A protein modification that effectively converts an L-aspartic acid residue to 1-chondroitin sulfate-L-aspartic acid ester" [PubMed:1898736, RESID:AA0219]
synonym	"1-aspartic acid ester with 6-chondroitin 4-sulfate" EXACT RESID-alternate []
synonym	"1-chondroitin sulfate-L-aspartic acid ester" EXACT RESID-name []
synonym	"MOD_RES Aspartate 1-(chondroitin 4-sulfate)-ester" EXACT UniProt-feature []
synonym	"poly[beta-1,4-D-glucopyranuronosyl-beta-1,3-(2-acetamido-2-deoxy-4-sulfate D-galactosyl)]beta-1,4-D-glucopyranuronosyl-beta-1,3-(2-acetamido-2-deoxy-4-sulfate-6-(1-L-aspartyl)-D-galactose)" EXACT RESID-alternate []
synonym	"protein-glycosaminoglycan-protein cross-link" EXACT RESID-alternate []
xref	DiffAvg: "441.36"
xref	DiffFormula: "C 14 H 19 N 1 O 13 S 1"
xref	DiffMono: "441.057711"
xref	Formula: "C 18 H 25 N 2 O 17 S 1"
xref	MassAvg: "573.45"
xref	MassMono: "573.087393"
xref	Origin: "D"
xref	TermSpec: "C-term"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.225. MOD:00225 S-(6-FMN)-L-cysteine

Table 227. Term [MOD:00225]
id	MOD:00225
name	S-(6-FMN)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(6-FMN)-L-cysteine." [PubMed:10869173, PubMed:1551870, PubMed:620783, RESID:AA0220, UniMod:409#C]
subset	PSI-MOD-slim
synonym	"®-2-amino-3-[6-riboflavin 5'-dihydrogen phosphate]sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"6-[S-cysteinyl]flavin mononucleotide" EXACT RESID-alternate []
synonym	"6-[S-cysteinyl]FMN" EXACT RESID-alternate []
synonym	"flavin mononucleotide" RELATED UniMod-description []
synonym	"FMNH" RELATED PSI-MS-label []
synonym	"MOD_RES S-6-FMN cysteine" EXACT UniProt-feature []
synonym	"S-(6-FMN)-L-cysteine" EXACT RESID-name []
synonym	"S6FMNCys" EXACT PSI-MOD-label []
xref	DiffAvg: "454.33"
xref	DiffFormula: "C 17 H 19 N 4 O 9 P 1 S 0"
xref	DiffMono: "454.088965"
xref	Formula: "C 20 H 24 N 5 O 10 P 1 S 1"
xref	MassAvg: "557.47"
xref	MassMono: "557.098150"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.226. MOD:00226 1'-(8alpha-FAD)-L-histidine

Table 228. Term [MOD:00226]
id	MOD:00226
name	1'-(8alpha-FAD)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 1'-(8alpha-FAD)-L-histidine." [DeltaMass:0, PubMed:10585424, PubMed:1396672, PubMed:4339951, PubMed:9261083, RESID:AA0221, UniMod:50#H]
comment	From DeltaMass: Average Mass: 784
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(1-[8alpha riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine]imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-(8alpha-FAD)-L-histidine" EXACT RESID-name []
synonym	"8alpha-(N(epsilon)-histidyl)FAD" EXACT RESID-alternate []
synonym	"8alpha-(N1'-histidyl)FAD" EXACT RESID-alternate []
synonym	"8alpha-N3-histidyl FAD" RELATED RESID-misnomer []
synonym	"FAD" RELATED PSI-MS-label []
synonym	"Flavin adenine dinucleotide" RELATED UniMod-description []
synonym	"MOD_RES Tele-8alpha-FAD histidine" EXACT UniProt-feature []
synonym	"N theta and N pi-(8alpha-Flavin) (on Histidine)" EXACT DeltaMass-label []
synonym	"N(tau)-(8alpha-FAD)-histidine" EXACT RESID-alternate []
synonym	"Nt8aFADHis" EXACT PSI-MOD-label []
synonym	"tele-(8alpha-FAD)-histidine" EXACT RESID-alternate []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2"
xref	DiffMono: "783.141485"
xref	Formula: "C 33 H 38 N 12 O 16 P 2"
xref	MassAvg: "920.68"
xref	MassMono: "920.200396"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.227. MOD:00227 omega-N-phospho-L-arginine

Table 229. Term [MOD:00227]
id	MOD:00227
name	omega-N-phospho-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to omega-N-phospho-L-arginine." [PubMed:8300603, RESID:AA0222, UniMod:21#R]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-([amino(phosphonoamino)methylidene]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-amino-5-(N'-phosphonocarbamimidamido)pentanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-delta-phosphonoguanidinovaleric acid" EXACT RESID-alternate []
synonym	"MOD_RES Phosphoarginine" EXACT UniProt-feature []
synonym	"N(gamma)-phosphoarginine" EXACT RESID-alternate []
synonym	"N(omega)-phosphono-L-arginine" EXACT RESID-alternate []
synonym	"N5-[imino(phosphonoamino)methyl]-L-ornithine" EXACT RESID-alternate []
synonym	"omega-N-phospho-L-arginine" EXACT RESID-name []
synonym	"PArg" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"phosphoarginine" EXACT RESID-alternate []
synonym	"Phosphorylation" RELATED UniMod-description []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 6 H 13 N 4 O 4 P 1"
xref	MassAvg: "236.17"
xref	MassMono: "236.067442"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01456 N-phosphorylated residue ! N-phosphorylated residue

2.228. MOD:00228 S-diphytanylglycerol diether-L-cysteine

Table 230. Term [MOD:00228]
id	MOD:00228
name	S-diphytanylglycerol diether-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-diphytanylglycerol diether-L-cysteine." [PubMed:7797461, PubMed:8195126, RESID:AA0223, UniMod:410]
comment	incidental to RESID:AA0043.
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-([(2S)-2,3-bis(3,7,11,15-tetramethylhexadecanyloxy)propyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"Archaeol" RELATED PSI-MS-label []
synonym	"LIPID S-archaeol cysteine" EXACT UniProt-feature []
synonym	"S-(diphytanylglyceryl)-L-cysteine" EXACT RESID-name []
synonym	"S-[2',3'-bis(phytanyloxy)propyl]cysteine" EXACT RESID-alternate []
synonym	"S-archaeol cysteine" EXACT RESID-alternate []
synonym	"S-diphytanylglycerol diether" RELATED UniMod-description []
synonym	"SPhyt2GlyceroCys" EXACT PSI-MOD-label []
xref	DiffAvg: "635.16"
xref	DiffFormula: "C 43 H 86 N 0 O 2 S 0"
xref	DiffMono: "634.662782"
xref	Formula: "C 46 H 91 N 1 O 3 S 1"
xref	MassAvg: "738.30"
xref	MassMono: "737.671967"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.229. MOD:00229 alpha-1-microglobulin-Ig alpha complex chromophore

Table 231. Term [MOD:00229]
id	MOD:00229
name	alpha-1-microglobulin-Ig alpha complex chromophore
def	"A protein modification that effectively converts two L-cysteine residues to form alpha-1-microglobulin-Ig alpha complex chromophore." [PubMed:11058759, PubMed:11877257, PubMed:7506257, PubMed:7535251, RESID:AA0224]
comment	Cross-link 2.
synonym	"alpha-1-microglobulin-Ig alpha complex chromophore" EXACT RESID-name []
synonym	"BINDING Multimeric 3-hydroxykynurenine chromophore (covalent)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 2 S 2"
xref	MassAvg: "204.26"
xref	MassMono: "204.002720"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.230. MOD:00230 bis-L-cysteinyl bis-L-histidino diiron disulfide

Table 232. Term [MOD:00230]
id	MOD:00230
name	bis-L-cysteinyl bis-L-histidino diiron disulfide
def	"A protein modification that effectively converts two L-cysteine residues, two L-histidine residues and a two-iron two-sulfur cluster to bis-L-cysteinyl bis-L-histidino diiron disulfide." [PubMed:2765515, PubMed:9651245, RESID:AA0225]
comment	Cross-link 4.
synonym	"bis-L-cysteinyl bis-L-histidino diiron disulfide" EXACT RESID-name []
synonym	"di-mu-sulfido(bis-S-cysteinyliron)(bis-N3'-histidinoiron)" EXACT RESID-systematic []
synonym	"METAL Iron-sulfur (2Fe-2S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (2Fe-2S); via pros nitrogen" EXACT UniProt-feature []
synonym	"Rieske iron-sulfur cofactor" EXACT RESID-alternate []
xref	DiffAvg: "171.78"
xref	DiffFormula: "C 0 Fe 2 H -4 N 0 O 0 S 2"
xref	DiffMono: "171.783814"
xref	FormalCharge: "2-"
xref	Formula: "C 18 Fe 2 H 20 N 8 O 4 S 4"
xref	MassAvg: "652.34"
xref	MassMono: "651.920007"
xref	Origin: "C, C, H, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.231. MOD:00231 hexakis-L-cysteinyl hexairon hexasulfide

Table 233. Term [MOD:00231]
id	MOD:00231
name	hexakis-L-cysteinyl hexairon hexasulfide
def	"A protein modification that effectively converts six L-cysteine residues and a six-iron six-sulfur cluster to hexakis-L-cysteinyl hexairon hexasulfide." [PubMed:1311311, PubMed:1318833, RESID:AA0226]
comment	Cross-link 6. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"hexa-mu3-sulfido-hexakis(cysteinato-kappaS)-hexairon" EXACT RESID-systematic []
synonym	"hexa-mu3-sulfido-hexakis(S-cysteinyliron)" EXACT RESID-alternate []
synonym	"hexakis-L-cysteinyl hexairon hexasulfide" EXACT RESID-name []
synonym	"prismane iron-sulfur cofactor" EXACT RESID-alternate []
xref	DiffAvg: "521.38"
xref	DiffFormula: "C 0 Fe 6 H -6 N 0 O 0 S 6"
xref	DiffMono: "521.395649"
xref	FormalCharge: "1-"
xref	Formula: "C 18 Fe 6 H 24 N 6 O 6 S 12"
xref	MassAvg: "1140.22"
xref	MassMono: "1139.450758"
xref	Origin: "C, C, C, C, C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.232. MOD:00232 N6-(phospho-5'-adenosine)-L-lysine

Table 234. Term [MOD:00232]
id	MOD:00232
name	N6-(phospho-5'-adenosine)-L-lysine
def	"A protein modification that effectively crosslinks an L-lysine residue and 5'-phosphoadenosine through a phosphoramide ester bond to form N6-(phospho-5'-adenosine)-L-lysine." [DeltaMass:316, PubMed:3882425, PubMed:4944632, RESID:AA0227, UniMod:405#K]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(5'-adenosine phosphonamino)hexanoic acid" EXACT RESID-systematic []
synonym	"5'-adenylic-N6-L-lysine" EXACT RESID-alternate []
synonym	"ACT_SITE N6-AMP-lysine intermediate" EXACT UniProt-feature []
synonym	"AMP binding site" RELATED UniMod-description []
synonym	"AMP Lysyl" EXACT DeltaMass-label []
synonym	"epsilon-5'-adenylic-L-lysine" EXACT RESID-alternate []
synonym	"L-lysine monoanhydride with 5'-adenylic acid" EXACT RESID-alternate []
synonym	"N(zeta)-5'-adenylic-L-lysine" EXACT RESID-alternate []
synonym	"N6-(phospho-5'-adenosine)-L-lysine" EXACT RESID-name []
synonym	"N6-L-lysine 5'-adenosine phosphoramidester" EXACT RESID-alternate []
synonym	"N6AMPLys" EXACT PSI-MOD-label []
synonym	"Phosphoadenosine" RELATED PSI-MS-label []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "C 16 H 24 N 7 O 7 P 1"
xref	MassAvg: "457.38"
xref	MassMono: "457.147483"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01165 adenylated residue ! adenylated residue

2.233. MOD:00233 N6-(phospho-5'-guanosine)-L-lysine

Table 235. Term [MOD:00233]
id	MOD:00233
name	N6-(phospho-5'-guanosine)-L-lysine
def	"A protein modification that effectively crosslinks an L-lysine residue and 5'-phosphoguanosine through a phosphoramide ester bond to form N6-(phospho-5'-guanosine)-L-lysine." [DeltaMass:304, PubMed:6092377, PubMed:6264433, RESID:AA0228, UniMod:413#K]
comment	From DeltaMass: Average Mass: 345 Formula:C10H12O5N7P1 Monoisotopic Mass Change:345.047 Average Mass Change:345.209 References:PE Sciex
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(5'-guanosine phosphonamino)hexanoic acid" EXACT RESID-systematic []
synonym	"5'-guanylic-N6-L-lysine" EXACT RESID-alternate []
synonym	"5’phos Guanosyl" EXACT DeltaMass-label []
synonym	"ACT_SITE N6-GMP-lysine intermediate" EXACT UniProt-feature []
synonym	"epsilon-5'-guanylic-L-lysine" EXACT RESID-alternate []
synonym	"L-lysine monoanhydride with 5'-guanylic acid" EXACT RESID-alternate []
synonym	"lysine guanosine-5'-monophosphate" EXACT RESID-alternate []
synonym	"N(zeta)-5'-guanylic-lysine" EXACT RESID-alternate []
synonym	"N6-(5'-guanylyl)-lysine" EXACT RESID-alternate []
synonym	"N6-(phospho-5'-guanosine)-L-lysine" EXACT RESID-name []
synonym	"N6-L-lysine 5'-guanosine phosphoramidester" EXACT RESID-alternate []
synonym	"N6GMPLys" EXACT PSI-MOD-label []
synonym	"phospho-guanosine" RELATED UniMod-description []
synonym	"Phosphoguanosine" RELATED PSI-MS-label []
xref	DiffAvg: "345.21"
xref	DiffFormula: "C 10 H 12 N 5 O 7 P 1"
xref	DiffMono: "345.047434"
xref	Formula: "C 16 H 24 N 7 O 8 P 1"
xref	MassAvg: "473.38"
xref	MassMono: "473.142397"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01163 guanylated residue ! guanylated residue

2.234. MOD:00234 L-cysteine glutathione disulfide

Table 236. Term [MOD:00234]
id	MOD:00234
name	L-cysteine glutathione disulfide
def	"A protein modification that effectively converts an L-cysteine residue to S-glutathionyl-L-cysteine." [ChEBI:21264, DeltaMass:0, OMSSA:51, PubMed:3083866, PubMed:8344916, RESID:AA0229, UniMod:55]
comment	From DeltaMass: Average Mass: 305
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-((2S)-2-((4R)-4-amino-4-carboxyl-1-oxobutyl)amino-3-(carboxylmethyl)amino-3-oxo-propyl)dithio-propanoic acid" EXACT RESID-systematic []
synonym	"cysteinyl glutathione" EXACT RESID-alternate []
synonym	"Glutathionation" EXACT DeltaMass-label []
synonym	"Glutathione" RELATED PSI-MS-label []
synonym	"glutathione disulfide" RELATED UniMod-description []
synonym	"glutathionec" EXACT OMSSA-label []
synonym	"L-cysteine glutathione disulfide" EXACT RESID-name []
synonym	"L-gamma-glutamyl-L-cysteinyl-glycine (2-1')-disulfide with L-cysteine" EXACT RESID-alternate []
synonym	"MOD_RES S-glutathionyl cysteine" EXACT UniProt-feature []
synonym	"N-(N-gamma-glutamyl-cystinyl)-glycine" EXACT RESID-alternate []
synonym	"SGltCys" EXACT PSI-MOD-label []
xref	DiffAvg: "305.30"
xref	DiffFormula: "C 10 H 15 N 3 O 6 S 1"
xref	DiffMono: "305.068156"
xref	Formula: "C 13 H 20 N 4 O 7 S 2"
xref	MassAvg: "408.44"
xref	MassMono: "408.077341"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.235. MOD:00235 S-nitrosyl-L-cysteine

Table 237. Term [MOD:00235]
id	MOD:00235
name	S-nitrosyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-nitrosyl-L-cysteine." [PubMed:10442087, PubMed:11562475, PubMed:15688001, PubMed:8626764, PubMed:8637569, RESID:AA0230, UniMod:275]
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-nitrososulfanyl-propanoic acid" EXACT RESID-systematic []
synonym	"L-cysteine nitrite ester" EXACT RESID-alternate []
synonym	"MOD_RES S-nitrosocysteine" EXACT UniProt-feature []
synonym	"Nitrosyl" RELATED PSI-MS-label []
synonym	"S-nitrosocysteine" EXACT RESID-alternate []
synonym	"S-nitrosyl-L-cysteine" EXACT RESID-name []
synonym	"S-nitrosylation" RELATED UniMod-description []
synonym	"SNOCys" EXACT PSI-MOD-label []
xref	DiffAvg: "29.00"
xref	DiffFormula: "C 0 H -1 N 1 O 1 S 0"
xref	DiffMono: "28.990164"
xref	Formula: "C 3 H 4 N 2 O 2 S 1"
xref	MassAvg: "132.14"
xref	MassMono: "131.999348"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.236. MOD:00236 N4-(ADP-ribosyl)-L-asparagine

Table 238. Term [MOD:00236]
id	MOD:00236
name	N4-(ADP-ribosyl)-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-(ADP-ribosyl)-L-asparagine." [PubMed:15842200, PubMed:2498316, RESID:AA0231, UniMod:213#N]
synonym	"(S)-2-amino-4-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]amino)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"ADP Ribose addition" RELATED UniMod-description []
synonym	"ADP-Ribosyl" RELATED PSI-MS-label []
synonym	"MOD_RES ADP-ribosylasparagine" EXACT UniProt-feature []
synonym	"N4-(ADP-ribosyl)-L-asparagine" EXACT RESID-name []
synonym	"N4-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-asparagine" EXACT RESID-alternate []
synonym	"N4-alpha-D-ribofuranosyl-L-asparagine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 19 H 27 N 7 O 15 P 2"
xref	MassAvg: "655.41"
xref	MassMono: "655.104036"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.237. MOD:00237 L-beta-methylthioaspartic acid

Table 239. Term [MOD:00237]
id	MOD:00237
name	L-beta-methylthioaspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to L-beta-methylthioaspartic acid." [DeltaMass:61, OMSSA:13, OMSSA:26, PubMed:15473684, PubMed:8844851, RESID:AA0232, UniMod:39#D]
subset	PSI-MOD-slim
synonym	"(2R,3Xi)-2-amino-3-(methylsulfanyl)butanedioic acid" EXACT RESID-systematic []
synonym	"3-(methylthio)-L-aspartic acid" EXACT RESID-name []
synonym	"3-carboxy-S-methyl-cysteine" EXACT RESID-alternate []
synonym	"3-methylthio-aspartic acid" EXACT RESID-alternate []
synonym	"3MeSAsp" EXACT PSI-MOD-label []
synonym	"beta-Methylthio-aspartic acid" EXACT DeltaMass-label []
synonym	"beta-methylthio-aspartic acid" EXACT RESID-alternate []
synonym	"Beta-methylthiolation" RELATED UniMod-description []
synonym	"bmethylthiold" EXACT OMSSA-label []
synonym	"Methylthio" RELATED UniMod-interim []
synonym	"methythiold" EXACT OMSSA-label []
synonym	"MOD_RES 3-methylthioaspartic acid" EXACT UniProt-feature []
xref	DiffAvg: "46.09"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 1"
xref	DiffMono: "45.987721"
xref	Formula: "C 5 H 7 N 1 O 3 S 1"
xref	MassAvg: "161.18"
xref	MassMono: "161.014664"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01153 methylthiolated residue ! methylthiolated residue

2.238. MOD:00238 5'-(N6-L-lysine)-L-topaquinone

Table 240. Term [MOD:00238]
id	MOD:00238
name	5'-(N6-L-lysine)-L-topaquinone
def	"A protein modification that effectively cross-links an L-lysine residue and an L-tyrosine residue by a carbon-nitrogen bond to form 5'-(N6-L-lysine)-L-topaquinone." [PubMed:8688089, RESID:AA0233]
comment	Cross-link 2; secondary to RESID:AA0147.
synonym	"1-[(S)-5-amino-5-carboxypentyl]amino-2-[(S)-2-amino-2-carboxyethyl]-2,6-cyclohexadien-4,5-dione" EXACT RESID-systematic []
synonym	"2'-(L-lys-N6-yl)-L-4',5'-topaquinone" EXACT RESID-name []
synonym	"2'-(L-lysine)-L-tyrosyl-4',5'-quinone" EXACT RESID-alternate []
synonym	"CROSSLNK Lysine tyrosylquinone (Lys-Tyr)" EXACT UniProt-feature []
synonym	"CROSSLNK Lysine tyrosylquinone (Tyr-Lys)" EXACT UniProt-feature []
synonym	"LTQ" EXACT RESID-alternate []
synonym	"lysyl oxidase cofactor" EXACT RESID-alternate []
xref	DiffAvg: "11.97"
xref	DiffFormula: "C 0 H -4 N 0 O 1"
xref	DiffMono: "11.963614"
xref	Formula: "C 15 H 17 N 3 O 4"
xref	MassAvg: "303.32"
xref	MassMono: "303.121906"
xref	Origin: "K, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.239. MOD:00239 S-methyl-L-cysteine

Table 241. Term [MOD:00239]
id	MOD:00239
name	S-methyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-methyl-L-cysteine." [PubMed:10660523, PubMed:11875433, PubMed:1339288, RESID:AA0234, UniMod:34#C]
subset	PSI-MOD-slim
synonym	"®-2-amino-3-(methylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE S-methylcysteine intermediate" EXACT UniProt-feature []
synonym	"L-3-(methylthio)alanine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES S-methylcysteine" EXACT UniProt-feature []
synonym	"S-methyl-L-cysteine" EXACT RESID-name []
synonym	"S-methylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"SMeCys" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 4 H 7 N 1 O 1 S 1"
xref	MassAvg: "117.17"
xref	MassMono: "117.024835"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00654 S-methylated residue ! S-methylated residue
is_a	MOD:01682 monomethylated L-cysteine ! monomethylated L-cysteine

2.240. MOD:00240 4-hydroxy-L-lysine

Table 242. Term [MOD:00240]
id	MOD:00240
name	4-hydroxy-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4-hydroxy-L-lysine." [PubMed:4005040, RESID:AA0235]
comment	This modification was not structurally confirmed. Later 5-hydroxy-L-lysine was found at a homologous position in the same protein from closely related species. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S,4R)-2,6-diamino-4-hydroxyhexanoic acid" EXACT RESID-systematic []
synonym	"4-hydroxy-L-lysine" EXACT RESID-name []
synonym	"4-hydroxylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"4HyLys" EXACT PSI-MOD-label []
synonym	"alpha,epsilon-diamino-gamma-hydroxycaproic acid" EXACT RESID-alternate []
synonym	"L-threo-gamma-hydroxylysine" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 2 O 2"
xref	MassAvg: "144.17"
xref	MassMono: "144.089878"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01047 monohydroxylated lysine ! monohydroxylated lysine

2.241. MOD:00241 N4-hydroxymethyl-L-asparagine

Table 243. Term [MOD:00241]
id	MOD:00241
name	N4-hydroxymethyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-hydroxymethyl-L-asparagine." [RESID:AA0236, UniMod:414]
comment	N4-methyl-L-asparagine, see MOD:0079, was found at a homologous position of the same protein in a closely related species. Since the peptide containing this modification was obtained by enzymatic cleavage, not cyanogen bromide cleavage, it could have experienced oxidation of the following methionine residue, leading to the erroneous attribution of a mass of 29 for the modification rather than 14. comment: This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S)-2-amino-4-[(hydroxymethyl)amino]-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N4-hydroxymethylbutanediamic acid" EXACT RESID-alternate []
synonym	"beta-hydroxymethylasparagine" EXACT RESID-alternate []
synonym	"Hydroxymethyl" RELATED PSI-MS-label []
synonym	"hydroxymethyl" RELATED UniMod-description []
synonym	"N(gamma)-hydroxymethylasparagine" EXACT RESID-alternate []
synonym	"N4-hydroxymethyl-L-asparagine" EXACT RESID-name []
synonym	"N4-hydroxymethylasparagine" EXACT RESID-alternate []
xref	DiffAvg: "30.03"
xref	DiffFormula: "C 1 H 2 N 0 O 1"
xref	DiffMono: "30.010565"
xref	Formula: "C 5 H 8 N 2 O 3"
xref	MassAvg: "144.13"
xref	MassMono: "144.053492"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.242. MOD:00242 O-(ADP-ribosyl)-L-serine

Table 244. Term [MOD:00242]
id	MOD:00242
name	O-(ADP-ribosyl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(ADP-ribosyl)-L-serine." [PubMed:15842200, PubMed:3141412, RESID:AA0237, UniMod:213#S]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]oxy)-propanoic acid" EXACT RESID-systematic []
synonym	"ADP Ribose addition" RELATED UniMod-description []
synonym	"ADP-Ribosyl" RELATED PSI-MS-label []
synonym	"MOD_RES ADP-ribosylserine" EXACT UniProt-feature []
synonym	"O-(ADP-ribosyl)-L-serine" EXACT RESID-name []
synonym	"O3-(ADP-ribosyl)-L-serine" EXACT RESID-alternate []
synonym	"O3-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-serine" EXACT RESID-alternate []
synonym	"O3-alpha-D-ribofuranosyl-L-serine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
synonym	"OADPRibSer" EXACT PSI-MOD-label []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 18 H 26 N 6 O 15 P 2"
xref	MassAvg: "628.38"
xref	MassMono: "628.093137"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.243. MOD:00243 L-cysteine oxazole-4-carboxylic acid

Table 245. Term [MOD:00243]
id	MOD:00243
name	L-cysteine oxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-serine residue to form L-cysteine oxazole-4-carboxylic acid." [PubMed:8183941, PubMed:8895467, RESID:AA0238]
comment	Cross-link 2.
synonym	"2-(1-azanyl-2-sulfanylethyl)-4-oxazolecarboxylic acid" EXACT RESID-alternate []
synonym	"2-[(1R)-1-amino-2-sulfanylethyl]-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Oxazole-4-carboxylic acid (Cys-Ser)" EXACT UniProt-feature []
synonym	"L-cysteine oxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 6 H 6 N 2 O 2 S 1"
xref	MassAvg: "170.19"
xref	MassMono: "170.014998"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser) ! oxazole/oxazoline ring crosslinked residues (Ser)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.244. MOD:00244 L-cysteine oxazoline-4-carboxylic acid

Table 246. Term [MOD:00244]
id	MOD:00244
name	L-cysteine oxazoline-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-serine residue to form L-cysteine oxazoline-4-carboxylic acid." [PubMed:1880060, RESID:AA0239]
comment	Cross-link 2.
synonym	"(4S)-2-[(1R)-1-amino-2-sulfanylethyl]-4,5-dihydro-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-sulfanylethyl]-4,5-dihydro-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Oxazoline-4-carboxylic acid (Cys-Ser)" EXACT UniProt-feature []
synonym	"L-cysteine oxazoline-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser) ! oxazole/oxazoline ring crosslinked residues (Ser)

2.245. MOD:00245 glycine oxazole-4-carboxylic acid

Table 247. Term [MOD:00245]
id	MOD:00245
name	glycine oxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks a glycine residue and an L-serine residue to form glycine oxazole-4-carboxylic acid." [PubMed:8183941, PubMed:8895467, RESID:AA0240]
comment	Cross-link 2.
synonym	"2-aminomethyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-azanylmethyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Oxazole-4-carboxylic acid (Gly-Ser)" EXACT UniProt-feature []
synonym	"glycine oxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 5 H 4 N 2 O 2"
xref	MassAvg: "124.10"
xref	MassMono: "124.027277"
xref	Origin: "G, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser) ! oxazole/oxazoline ring crosslinked residues (Ser)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.246. MOD:00246 glycine thiazole-4-carboxylic acid

Table 248. Term [MOD:00246]
id	MOD:00246
name	glycine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue to form glycine thiazole-4-carboxylic acid." [ChEBI:21276, PubMed:8183941, PubMed:8895467, RESID:AA0241]
comment	Cross-link 2.
synonym	"2-(aminomethyl)-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-(azanylmethyl)-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Gly-Cys)" EXACT UniProt-feature []
synonym	"glycine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 5 H 4 N 2 O 1 S 1"
xref	MassAvg: "140.16"
xref	MassMono: "140.004434"
xref	Origin: "C, G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.247. MOD:00247 L-serine thiazole-4-carboxylic acid

Table 249. Term [MOD:00247]
id	MOD:00247
name	L-serine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-serine residue to form L-serine thiazole-4-carboxylic acid." [PubMed:8183941, PubMed:8895467, RESID:AA0242]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-hydroxyethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-hydroxyethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Ser-Cys)" EXACT UniProt-feature []
synonym	"L-serine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 6 H 6 N 2 O 2 S 1"
xref	MassAvg: "170.19"
xref	MassMono: "170.014998"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.248. MOD:00248 L-phenylalanine thiazole-4-carboxylic acid

Table 250. Term [MOD:00248]
id	MOD:00248
name	L-phenylalanine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-phenylalanine residue to form L-phenylalanine thiazole-4-carboxylic acid." [PubMed:1880060, RESID:AA0243]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-phenylethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-phenylethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Phe-Cys)" EXACT UniProt-feature []
synonym	"L-phenylalanine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 12 H 10 N 2 O 1 S 1"
xref	MassAvg: "230.29"
xref	MassMono: "230.051384"
xref	Origin: "C, F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.249. MOD:00249 L-cysteine thiazole-4-carboxylic acid

Table 251. Term [MOD:00249]
id	MOD:00249
name	L-cysteine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks two L-cysteine residues to form L-cysteine thiazole-4-carboxylic acid." [PubMed:1880060, RESID:AA0244]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-sulfanylethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-sulfanylethyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Cys-Cys)" EXACT UniProt-feature []
synonym	"L-cysteine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 6 H 6 N 2 O 1 S 2"
xref	MassAvg: "186.25"
xref	MassMono: "185.992155"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.250. MOD:00250 L-lysine thiazole-4-carboxylic acid

Table 252. Term [MOD:00250]
id	MOD:00250
name	L-lysine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-lysine residue to form L-lysine thiazole-4-carboxylic acid." [PubMed:1880060, RESID:AA0245]
comment	Cross-link 2. Lysine is now thought not to be encoded in the peptide sequence modified to produce GE2270. See RESID:AA0470. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"2-[(1S)-1,5-diaminopentyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1,5-bis(azanyl)pentyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"L-lysine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 9 H 13 N 3 O 1 S 1"
xref	MassAvg: "211.28"
xref	MassMono: "211.077933"
xref	Origin: "C, K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.251. MOD:00251 O-(phospho-5'-DNA)-L-serine

Table 253. Term [MOD:00251]
id	MOD:00251
name	O-(phospho-5'-DNA)-L-serine
def	"A protein modification that effectively crosslinks an L-serine residue and the 5'-end of DNA through a phosphodiester bond to form O-(phospho-5'-DNA)-L-serine." [PubMed:7142163, PubMed:7265205, RESID:AA0246]
synonym	"(S)-2-amino-3-(5'-deoxyribonucleic acid phosphonoxy)propanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE O-(5'-phospho-DNA)-serine intermediate" EXACT UniProt-feature []
synonym	"MOD_RES O-(5'-phospho-DNA)-serine" EXACT UniProt-feature []
synonym	"O-(phospho-5'-DNA)-L-serine" EXACT RESID-name []
synonym	"O3-(phospho-5'-DNA)-L-serine" EXACT RESID-alternate []
synonym	"O3-L-serine 5'-DNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "78.97"
xref	DiffFormula: "C 0 H 0 N 0 O 3 P 1"
xref	DiffMono: "78.958505"
xref	Formula: "C 3 H 5 N 1 O 5 P 1"
xref	MassAvg: "166.05"
xref	MassMono: "165.990534"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.252. MOD:00252 keratan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine

Table 254. Term [MOD:00252]
id	MOD:00252
name	keratan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine
def	"A protein modification that effectively cross-links an L-threonine residue to the polymer keratan sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide." [PubMed:1417734, PubMed:3472204, RESID:AA0247]
synonym	"keratan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine" EXACT RESID-name []
synonym	"keratosulfate" EXACT RESID-alternate []
synonym	"poly[beta-1,4-(2-acetamido-2-deoxy-6-sulfate D-glucosyl)-beta-1,3-D-galactosyl]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-threonine" EXACT RESID-systematic []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 4 H 6 N 1 O 2"
xref	MassAvg: "100.10"
xref	MassMono: "100.039853"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine

2.253. MOD:00253 L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) (Sec)

Table 255. Term [MOD:00253]
id	MOD:00253
name	L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) (Sec)
def	"A protein modification that effectively converts an L-selenocysteine residue to L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)." [PubMed:14235557, PubMed:2211698, PubMed:8052647, PubMed:9036855, RESID:AA0248#SEC, UniMod:415]
xref	DiffAvg: "1572.02"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 26 P 4 S 4 Se 0"
xref	DiffMono: "1572.985775"
xref	Formula: "C 43 H 52 Mo 1 N 21 O 27 P 4 S 4 Se 1"
xref	MassAvg: "1722.07"
xref	MassMono: "1723.939410"
xref	Origin: "U"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification
is_a	MOD:01158 modified L-selenocysteine residue ! modified L-selenocysteine residue

2.254. MOD:00254 O4'-(phospho-5'-RNA)-L-tyrosine

Table 256. Term [MOD:00254]
id	MOD:00254
name	O4'-(phospho-5'-RNA)-L-tyrosine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and the 5'-end of RNA through a phosphodiester to form O4'-(phospho-5'-RNA)-L-tyrosine." [PubMed:1702164, PubMed:209034, PubMed:217003, PubMed:6264310, RESID:AA0249]
synonym	"(S)-2-amino-3-[4-(5'-ribonucleic acid phosphonoxy)phenyl]propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES O-(5'-phospho-RNA)-tyrosine" EXACT UniProt-feature []
synonym	"O4'-(phospho-5'-RNA)-L-tyrosine" EXACT RESID-name []
synonym	"O4'-L-tyrosine 5'-RNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 9 H 10 N 1 O 5 P 1"
xref	MassAvg: "243.15"
xref	MassMono: "243.029659"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00751 ribonucleic acid linked residue ! ribonucleic acid linked residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.255. MOD:00255 3-(3'-L-histidyl)-L-tyrosine

Table 257. Term [MOD:00255]
id	MOD:00255
name	3-(3'-L-histidyl)-L-tyrosine
def	"A protein modification that effectively cross-links an L-histidine residue and an L-tyrosine residue by a carbon-nitrogen bond to form 3-(3'-L-histidyl)-L-tyrosine." [PubMed:9144772, RESID:AA0250]
comment	Cross-link 2.
synonym	"(2S,3R)-2-amino-3-(5-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl)-3-(4-hydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3-(3'-L-histidyl)-L-tyrosine" EXACT RESID-name []
synonym	"3-(N3'-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"3-(pi-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"3-(pros-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"beta-(N(delta)-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"beta-(N3'-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"CROSSLNK 3'-histidyl-3-tyrosine (His-Tyr)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 15 H 14 N 4 O 3"
xref	MassAvg: "298.30"
xref	MassMono: "298.106590"
xref	Origin: "H, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.256. MOD:00256 L-methionine sulfone

Table 258. Term [MOD:00256]
id	MOD:00256
name	L-methionine sulfone
def	"A protein modification that dioxygenates an L-methionine residue to L-methionine sulfone." [DeltaMass:205, OMSSA:115, PubMed:12686488, PubMed:7786407, PubMed:7791219, PubMed:9252331, RESID:AA0251, UniMod:425#M]
comment	DeltaMass gives the formula C 5 H 9 N 3 O 1 S 1 with mass 163
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-(methylsulfonyl)butanoic acid" EXACT RESID-systematic []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"L-methionine S,S-dioxide" EXACT RESID-alternate []
synonym	"L-methionine sulfone" EXACT RESID-name []
synonym	"MethionylSulphone" EXACT DeltaMass-label []
synonym	"MetO2" EXACT PSI-MOD-label []
synonym	"MOD_RES Methionine sulfone" EXACT UniProt-feature []
synonym	"Oxidation of Methionine (to Sulphone)" EXACT DeltaMass-label []
synonym	"S,S-dioxymethionine" EXACT RESID-alternate []
synonym	"suphonem" EXACT OMSSA-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2 S 0"
xref	DiffMono: "31.989829"
xref	Formula: "C 5 H 9 N 1 O 3 S 1"
xref	MassAvg: "163.19"
xref	MassMono: "163.030314"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00709 sulfur oxygenated L-methionine ! sulfur oxygenated L-methionine
is_a	MOD:01855 sulfur dioxygenated residue ! sulfur dioxygenated residue

2.257. MOD:00257 dipyrrolylmethanemethyl-L-cysteine

Table 259. Term [MOD:00257]
id	MOD:00257
name	dipyrrolylmethanemethyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to dipyrrolylmethanemethyl-L-cysteine." [PubMed:3042456, PubMed:3196304, PubMed:3421931, PubMed:8727319, RESID:AA0252, UniMod:416]
synonym	"(2S)-3-[5-[4-(2-carboxy)ethyl-3-carboxymethyl-1-pyrrol-2-yl]methyl-4-(2-carboxy)ethyl-3-carboxymethyl-1-pyrrol-2-yl]methylthio-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"3-[5-(3-acetic acid-4-propanoic acid-1-pyrrol-2-yl)methyl-3-acetic acid-4-propanoic acid-1-pyrrol-2-yl]methylthio-2-aminopropanoic acid" EXACT RESID-alternate []
synonym	"dipyrrole cofactor" EXACT RESID-alternate []
synonym	"Dipyrrolylmethanemethyl" RELATED PSI-MS-label []
synonym	"dipyrrolylmethanemethyl" RELATED UniMod-description []
synonym	"dipyrrolylmethanemethyl-L-cysteine" EXACT RESID-name []
synonym	"dipyrrolylmethyl-L-cysteine" EXACT RESID-alternate []
synonym	"dipyrromethane cofactor" EXACT RESID-alternate []
synonym	"MOD_RES S-(dipyrrolylmethanemethyl)cysteine" EXACT UniProt-feature []
synonym	"pyrromethane cofactor" EXACT RESID-alternate []
xref	DiffAvg: "418.40"
xref	DiffFormula: "C 20 H 22 N 2 O 8 S 0"
xref	DiffMono: "418.137616"
xref	Formula: "C 23 H 27 N 3 O 9 S 1"
xref	MassAvg: "521.54"
xref	MassMono: "521.146800"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.258. MOD:00258 S-(2-aminovinyl)-3-methyl-D-cysteine

Table 260. Term [MOD:00258]
id	MOD:00258
name	S-(2-aminovinyl)-3-methyl-D-cysteine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form S-(2-aminovinyl)-3-methyl-D-cysteine." [PubMed:9119018, RESID:AA0253]
comment	Cross-link 2.
synonym	"(2S,3S)-2-amino-3-[((Z)-2-aminoethenyl)sulfanyl]butanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-[(2-aminovinyl)sulfanyl]butanoic acid" EXACT RESID-alternate []
synonym	"CROSSLNK S-(2-aminovinyl)-3-methyl-D-cysteine (Thr-Cys)" EXACT UniProt-feature []
synonym	"decarboxylated methyllanthionine" EXACT RESID-alternate []
synonym	"S-(2-aminovinyl)-3-methyl-D-cysteine" EXACT RESID-name []
xref	DiffAvg: "-64.04"
xref	DiffFormula: "C -1 H -4 N 0 O -3 S 0"
xref	DiffMono: "-64.016044"
xref	Formula: "C 6 H 9 N 2 O 1 S 1"
xref	MassAvg: "157.21"
xref	MassMono: "157.043559"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.259. MOD:00259 O4'-(phospho-5'-DNA)-L-tyrosine

Table 261. Term [MOD:00259]
id	MOD:00259
name	O4'-(phospho-5'-DNA)-L-tyrosine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and the 5'-end of DNA through a phosphodiester bond to form O4'-(phospho-5'-DNA)-L-tyrosine." [PubMed:1861973, PubMed:2940511, PubMed:3684578, RESID:AA0254]
synonym	"(S)-2-amino-3-[4-(5'-deoxyribonucleic acid phosphonoxy)phenyl]propanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE O-(5'-phospho-DNA)-tyrosine intermediate" EXACT UniProt-feature []
synonym	"MOD_RES O-(5'-phospho-DNA)-tyrosine" EXACT UniProt-feature []
synonym	"O4'-(phospho-5'-DNA)-L-tyrosine" EXACT RESID-name []
synonym	"O4'-L-tyrosine 5'-DNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 9 H 10 N 1 O 5 P 1"
xref	MassAvg: "243.15"
xref	MassMono: "243.029659"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.260. MOD:00260 O-(phospho-5'-DNA)-L-threonine

Table 262. Term [MOD:00260]
id	MOD:00260
name	O-(phospho-5'-DNA)-L-threonine
def	"A protein modification that effectively crosslinks an L-threonine residue and the 5'-end of DNA through a phosphodiester bond to form O-(phospho-5'-DNA)-L-threonine." [PubMed:3081736, RESID:AA0255]
synonym	"(S)-2-amino-3-(5'-deoxyribonucleic acid phosphonoxy)butanoic acid" EXACT RESID-systematic []
synonym	"O-(phospho-5'-DNA)-L-threonine" EXACT RESID-name []
synonym	"O3-(phospho-5'-DNA)-L-threonine" EXACT RESID-alternate []
synonym	"O3-L-threonine 5'-DNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "78.97"
xref	DiffFormula: "C 0 H 0 N 0 O 3 P 1"
xref	DiffMono: "78.958505"
xref	Formula: "C 4 H 7 N 1 O 5 P 1"
xref	MassAvg: "180.08"
xref	MassMono: "180.006184"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.261. MOD:00261 O4'-(phospho-5'-uridine)-L-tyrosine

Table 263. Term [MOD:00261]
id	MOD:00261
name	O4'-(phospho-5'-uridine)-L-tyrosine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and 5'-phosphouridine through a phosphodiester bond to form O4'-(phospho-5'-uridine)-L-tyrosine." [DeltaMass:0, PubMed:11467524, PubMed:2885322, RESID:AA0256, UniMod:417#Y]
comment	From DeltaMass: Average Mass: 306.
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-[4-(5'-uridine phosphonoxy)phenyl]propanoic acid" EXACT RESID-systematic []
synonym	"5'-uridylic-O-tyrosine" EXACT RESID-alternate []
synonym	"hydrogen 5'-uridylate tyrosine ester" EXACT RESID-alternate []
synonym	"MOD_RES O-UMP-tyrosine" EXACT UniProt-feature []
synonym	"O-Uridinylylation (of Tyrosine)" EXACT DeltaMass-label []
synonym	"O4'-(phospho-5'-uridine)-L-tyrosine" EXACT RESID-name []
synonym	"O4'-L-tyrosine 5'-uridine phosphodiester" EXACT RESID-alternate []
synonym	"OUMPTyr" EXACT PSI-MOD-label []
synonym	"PhosphoUridine" RELATED PSI-MS-label []
synonym	"uridine phosphodiester" RELATED UniMod-description []
xref	DiffAvg: "306.17"
xref	DiffFormula: "C 9 H 11 N 2 O 8 P 1"
xref	DiffMono: "306.025302"
xref	Formula: "C 18 H 20 N 3 O 10 P 1"
xref	MassAvg: "469.34"
xref	MassMono: "469.088630"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01166 uridylated residue ! uridylated residue

2.262. MOD:00262 N-(L-glutamyl)-L-tyrosine

Table 264. Term [MOD:00262]
id	MOD:00262
name	N-(L-glutamyl)-L-tyrosine
def	"A protein modification that effectively forms a peptide bond between a C-terminal L-glutamic acid residue and a free L-tyrosine." [ChEBI:21477, PubMed:6387372, PubMed:8093886, RESID:AA0257]
comment	Cross-link 2.
synonym	"(S,S)-2-(2-aminopentanedio-1-yl)amino-3-(4-hydoxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"L-glutamyl L-tyrosine" EXACT RESID-name []
synonym	"N-(L-glutamyl)-L-tyrosine" EXACT RESID-alternate []
synonym	"SITE Involved in polymerization" EXACT UniProt-feature []
xref	DiffAvg: "-17.01"
xref	DiffFormula: "C 0 H -1 N 0 O -1"
xref	DiffMono: "-17.002740"
xref	Formula: "C 14 H 16 N 2 O 5"
xref	MassAvg: "292.29"
xref	MassMono: "292.105922"
xref	Origin: "E, Y"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.263. MOD:00263 S-phycoviolobilin-L-cysteine

Table 265. Term [MOD:00263]
id	MOD:00263
name	S-phycoviolobilin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound phycoviolobilin." [PubMed:2106585, PubMed:3208761, RESID:AA0258, UniMod:387]
synonym	"(4S)-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-18-ethyl-4,5-dihydro-2,7,13,17-tetramethyl-(21H,22H,24H)-biladiene-bc-1,19-dione" EXACT RESID-systematic []
synonym	"BINDING Phycoviolobilin chromophore (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"cryptobiliviolin" EXACT RESID-alternate []
synonym	"cryptoviolin" EXACT RESID-alternate []
synonym	"cryptoviolobilin" EXACT RESID-alternate []
synonym	"PBV" EXACT RESID-alternate []
synonym	"Phycocyanobilin" RELATED PSI-MS-label []
synonym	"phycocyanobilin" RELATED UniMod-description []
synonym	"PVB" EXACT RESID-alternate []
synonym	"PXB" EXACT RESID-alternate []
synonym	"S-phycobiliviolin-L-cysteine" EXACT RESID-alternate []
synonym	"S-phycoviolobilin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "586.69"
xref	DiffFormula: "C 33 H 38 N 4 O 6 S 0"
xref	DiffMono: "586.279135"
xref	Formula: "C 36 H 43 N 5 O 7 S 1"
xref	MassAvg: "689.83"
xref	MassMono: "689.288320"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.264. MOD:00264 phycoerythrobilin-bis-L-cysteine

Table 266. Term [MOD:00264]
id	MOD:00264
name	phycoerythrobilin-bis-L-cysteine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues and the tetrapyrrole compound phycoerythrobilin." [PubMed:3208761, PubMed:3838747, RESID:AA0259]
comment	Cross-link 2.
synonym	"(2S,3R,16R)-3,18-bis-[®-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-2,3,15,16-tetrahydrobilin-1,19(21H,22H,24H)-dione" EXACT RESID-systematic []
synonym	"3,18-bis-[1-((2-amino-2-carboxy)ethylsulfanyl)ethyl]-2,3,15,16-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-(21H,22H,24H)-biladiene-ab-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"BINDING Phycoerythrobilin chromophore (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"PEB" EXACT RESID-alternate []
synonym	"phycoerythrobilin biscysteine adduct" EXACT RESID-alternate []
synonym	"phycoerythrobilin-bis-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "586.69"
xref	DiffFormula: "C 33 H 38 N 4 O 6 S 0"
xref	DiffMono: "586.279135"
xref	Formula: "C 39 H 48 N 6 O 8 S 2"
xref	MassAvg: "792.97"
xref	MassMono: "792.297505"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.265. MOD:00265 phycourobilin-bis-L-cysteine

Table 267. Term [MOD:00265]
id	MOD:00265
name	phycourobilin-bis-L-cysteine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues and the tetrapyrrole compound phycourobilin." [PubMed:3208761, PubMed:3838665, PubMed:3838747, PubMed:8876649, RESID:AA0260]
comment	Cross-link 2.
synonym	"3,18-bis(1-[®-2-amino-2-carboxyethyl]sulfanylethyl)-2,7,13,17-tetramethyl-1,19-dioxo-4,5,15,16-tetrahydro-(21H,22H,24H)-bilene-b-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"3,18-bis(1-[®-2-amino-2-carboxyethyl]sulfanylethyl)-8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-4,5,15,16-tetrahydro-(21H,22H,24H)-bilene-b-1,19(4H,16H)-dione" EXACT RESID-systematic []
synonym	"BINDING Phycourobilin chromophore (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"phycourobilin biscysteine adduct" EXACT RESID-alternate []
synonym	"phycourobilin-bis-L-cysteine" EXACT RESID-name []
synonym	"PUB" EXACT RESID-alternate []
xref	DiffAvg: "586.69"
xref	DiffFormula: "C 33 H 38 N 4 O 6 S 0"
xref	DiffMono: "586.279135"
xref	Formula: "C 39 H 48 N 6 O 8 S 2"
xref	MassAvg: "792.97"
xref	MassMono: "792.297505"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.266. MOD:00266 N-L-glutamyl-poly-L-glutamic acid

Table 268. Term [MOD:00266]
id	MOD:00266
name	N-L-glutamyl-poly-L-glutamic acid
def	"A protein modification that effectively forms a peptide bond between a C-terminal L-glutamic acid residue and one or more free L-glutamic acid molecules to form N-(L-glutamyl)-poly-L-glutamic acid." [PubMed:2570347, PubMed:328274, RESID:AA0261]
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 10 H 15 N 2 O 7"
xref	MassAvg: "275.24"
xref	MassMono: "275.087926"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.267. MOD:00267 L-cysteine sulfinic acid

Table 269. Term [MOD:00267]
id	MOD:00267
name	L-cysteine sulfinic acid
def	"A protein modification that effectively dioxygenates an L-cysteine residue to L-cysteine sulfinic acid." [ChEBI:16345, OMSSA:162, PubMed:12686488, PubMed:9252331, PubMed:9586994, RESID:AA0262, UniMod:425#C]
comment	"Hyun Ae Woo, et. al., Science 300 (5619), 653-656"
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-sulfinopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-2-carboxyethanesulfinic acid" EXACT RESID-alternate []
synonym	"2-amino-3-(dioxido-lambda(6)-sulfanyl)propanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-3-sulfonylpropanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"3-sulfinoalanine" EXACT RESID-alternate []
synonym	"3-sulphinoalanine" EXACT RESID-alternate []
synonym	"CysO2H" EXACT PSI-MOD-label []
synonym	"cysteine sulphinic acid" EXACT RESID-alternate []
synonym	"cysteine-S,S-dioxide [tautomer]" EXACT RESID-alternate []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"L-cysteine sulfinic acid" EXACT RESID-name []
synonym	"MOD_RES Cysteine sulfinic acid (-SO2H)" EXACT UniProt-feature []
synonym	"S-cysteinesulfinic acid" EXACT RESID-alternate []
synonym	"S-sulfinocysteine" EXACT RESID-alternate []
synonym	"sulfinicacid" EXACT OMSSA-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2 S 0"
xref	DiffMono: "31.989829"
xref	Formula: "C 3 H 5 N 1 O 3 S 1"
xref	MassAvg: "135.14"
xref	MassMono: "134.999014"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01855 sulfur dioxygenated residue ! sulfur dioxygenated residue

2.268. MOD:00268 L-3',4',5'-trihydroxyphenylalanine

Table 270. Term [MOD:00268]
id	MOD:00268
name	L-3',4',5'-trihydroxyphenylalanine
def	"A protein modification that effectively converts an L-tyrosine residue to L-3',4',5'-trihydroxyphenylalanine." [DeltaMass:0, PubMed:12686488, PubMed:12771378, PubMed:8554314, PubMed:9252331, PubMed:9434739, RESID:AA0263, UniMod:425#Y]
comment	From DeltaMass: Average Mass: 32
synonym	"(S)-2-amino-3-(3,4,5-trihydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3,4,6-Trihydroxy-Phenylalanine (from Tyrosine) (TOPA)" EXACT DeltaMass-label []
synonym	"35Hy2Tyr" EXACT PSI-MOD-label []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"L-3',4',5'-trihydroxyphenylalanine" EXACT RESID-name []
synonym	"L-3,4,5-TOPA" EXACT RESID-alternate []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 9 H 9 N 1 O 4"
xref	MassAvg: "195.17"
xref	MassMono: "195.053158"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:00707 hydroxylated tyrosine ! hydroxylated tyrosine

2.269. MOD:00269 O-(sn-1-glycerophosphoryl)-L-serine

Table 271. Term [MOD:00269]
id	MOD:00269
name	O-(sn-1-glycerophosphoryl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(sn-1-glycerophosphoryl)-L-serine." [PubMed:8645220, RESID:AA0264, UniMod:419#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-[(2Xi)-2,3-dihydroxypropyl]phosphonoxypropanoic acid" EXACT RESID-systematic []
synonym	"alpha-glycerophosphoryl serine" EXACT RESID-alternate []
synonym	"Glycerophospho" RELATED PSI-MS-label []
synonym	"glycerophospho" RELATED UniMod-description []
synonym	"glycerophosphoserine" EXACT RESID-alternate []
synonym	"MOD_RES O-(sn-1-glycerophosphoryl)serine" EXACT UniProt-feature []
synonym	"O-(sn-1-glycerophosphoryl)-L-serine" EXACT RESID-name []
synonym	"O3-(sn-1-glycerophosphoryl)-L-serine" EXACT RESID-alternate []
synonym	"O3-2,3-dihydroxypropyl hydrogen phosphate-L-serine ester" EXACT RESID-alternate []
synonym	"O3-L-serine glyceryl-1-phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "154.06"
xref	DiffFormula: "C 3 H 7 N 0 O 5 P 1"
xref	DiffMono: "154.003110"
xref	Formula: "C 6 H 12 N 1 O 7 P 1"
xref	MassAvg: "241.14"
xref	MassMono: "241.035138"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.270. MOD:00270 1-thioglycine (internal)

Table 272. Term [MOD:00270]
id	MOD:00270
name	1-thioglycine (internal)
def	"A protein modification that effectively converts a glycine residue to an internal 1-thioglycine." [PubMed:11463785, PubMed:9367957, RESID:AA0265#INT]
comment	This modification occurs naturally in two forms. At an interior peptide location it exists as aminoethanethionic acid (or aminoethanethioic O-acid). At the carboxyl-terminal it exists as aminoethanethiolic acid (or aminoethanethioic S-acid).
subset	PSI-MOD-slim
synonym	"1-thioglycine" EXACT RESID-name []
synonym	"2-amino-1-sulfanylethanone" EXACT RESID-alternate []
synonym	"aminoethanethioic acid" EXACT RESID-systematic []
synonym	"aminoethanethioic O-acid" EXACT RESID-alternate []
synonym	"aminoethanethionic acid" EXACT RESID-alternate []
synonym	"aminothioacetic acid" EXACT RESID-alternate []
synonym	"Carboxy→Thiocarboxy" RELATED PSI-MS-label []
synonym	"MOD_RES 1-thioglycine" EXACT UniProt-feature []
synonym	"S(O)Gly" EXACT PSI-MOD-label []
synonym	"thiocarboxylic acid" RELATED UniMod-description []
xref	DiffAvg: "16.06"
xref	DiffFormula: "C 0 H 0 N 0 O -1 S 1"
xref	DiffMono: "15.977156"
xref	Formula: "C 2 H 3 N 1 S 1"
xref	MassAvg: "73.11"
xref	MassMono: "72.998620"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01625 1-thioglycine ! 1-thioglycine

2.271. MOD:00271 heme P460-bis-L-cysteine-L-tyrosine

Table 273. Term [MOD:00271]
id	MOD:00271
name	heme P460-bis-L-cysteine-L-tyrosine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues, the C-3' of a tyrosine residue, and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:8325841, PubMed:9095195, RESID:AA0266]
comment	Cross-link 3.
synonym	"(10S,11S)-[7,12-bis((S)-1-[(®-2-amino-2-carboxy)ethylsulfanyl]ethyl)-10-(2-hydroxy-5-[(S)-2-amino-2-carboxy]ethylphenyl)-3,8,13,17-tetramethyl-21H,23H-10,11-dihydroporphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via 3 links)" EXACT UniProt-feature []
synonym	"bis(S-cysteinyl)-(tyros-3'-yl)-heme" EXACT RESID-alternate []
synonym	"heme P460-bis-L-cysteine-L-tyrosine" EXACT RESID-name []
xref	DiffAvg: "614.48"
xref	DiffFormula: "C 34 Fe 1 H 30 N 4 O 4 S 0"
xref	DiffMono: "614.161643"
xref	Formula: "C 49 Fe 1 H 49 N 7 O 8 S 2"
xref	MassAvg: "983.94"
xref	MassMono: "983.243341"
xref	Origin: "C, C, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.272. MOD:00272 O-(phospho-5'-adenosine)-L-threonine

Table 274. Term [MOD:00272]
id	MOD:00272
name	O-(phospho-5'-adenosine)-L-threonine
def	"A protein modification that effectively crosslinks an L-threonine residue and 5'-phosphoadenosine through a phosphodiester bond to form O-(phospho-5'-adenosine)-L-threonine." [PubMed:2989287, PubMed:8917428, RESID:AA0267, UniMod:405#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(5'-adenosine phosphonoxy)butanoic acid" EXACT RESID-systematic []
synonym	"5'-adenylic-O3-L-threonine" EXACT RESID-alternate []
synonym	"ACT_SITE O-AMP-threonine intermediate" EXACT UniProt-feature []
synonym	"AMP binding site" RELATED UniMod-description []
synonym	"beta-5'-adenylic-L-threonine" EXACT RESID-alternate []
synonym	"L-threonine monoanhydride with 5'-adenylic acid" EXACT RESID-alternate []
synonym	"MOD_RES O-AMP-threonine" EXACT UniProt-feature []
synonym	"O(gamma)-5'-adenylic-L-threonine" EXACT RESID-alternate []
synonym	"O-(phospho-5'-adenosine)-L-threonine" EXACT RESID-name []
synonym	"O3-(phospho-5'-adenosine)-L-threonine" EXACT RESID-alternate []
synonym	"O3-L-threonine 5'-adenosine phosphodiester" EXACT RESID-alternate []
synonym	"Phosphoadenosine" RELATED PSI-MS-label []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "C 14 H 19 N 6 O 8 P 1"
xref	MassAvg: "430.31"
xref	MassMono: "430.100198"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01165 adenylated residue ! adenylated residue

2.273. MOD:00273 tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino tetrairon disulfide trioxide

Table 275. Term [MOD:00273]
id	MOD:00273
name	tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino tetrairon disulfide trioxide
def	"A protein modification that effectively converts four L-cysteine residues, two L-glutamic acid residues, an L-histidine residue and a four-iron three-sulfur three-oxygen cluster to tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino tetrairon disulfide trioxide." [PubMed:12764602, RESID:AA0268]
comment	Cross-link 7; secondary to RESID:AA0269.
synonym	"4Fe-2S-3O cluster" EXACT RESID-alternate []
synonym	"hybrid four iron cluster 2" EXACT RESID-alternate []
synonym	"METAL Iron-oxo-sulfur (4Fe-2O-2S)" EXACT UniProt-feature []
synonym	"METAL Iron-oxo-sulfur (4Fe-2O-2S); via persulfide group" EXACT UniProt-feature []
synonym	"METAL Iron-oxo-sulfur (4Fe-2O-2S); via tele nitrogen" EXACT UniProt-feature []
synonym	"mu-1:2kappaO-oxido-mu-1:3kappaO-oxido-mu-2:4kappaO-oxido-mu-3:4kappaS-sulfido-mu3-2:3:4kappaS-sulfido-S-cysteinyl-N1'-histidino-O5-glutamato 1-iron-S5-cysteine persulfido-O5-glutamato 2-iron-3,4-bis-(S-cysteinyl iron)" EXACT RESID-systematic []
synonym	"prismane iron-sulfur cofactor" RELATED RESID-misnomer []
synonym	"tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino tetrairon disulfide trioxide" EXACT RESID-name []
xref	DiffAvg: "360.50"
xref	DiffFormula: "C 0 Fe 4 H -7 N 0 O 3 S 3"
xref	DiffMono: "360.585932"
xref	Formula: "C 28 Fe 4 H 34 N 9 O 14 S 7"
xref	MassAvg: "1168.43"
xref	MassMono: "1167.766769"
xref	Origin: "C, C, C, C, E, E, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.274. MOD:00274 L-cysteine persulfide

Table 276. Term [MOD:00274]
id	MOD:00274
name	L-cysteine persulfide
def	"A protein modification that effectively replaces the hydrogen atom of a cysteine sulfanyl group with a sulfanyl group, forming a disulfanyl group, and converting an L-cysteine residue to L-cysteine persulfide." [ChEBI:28839, PubMed:15096637, PubMed:4276457, PubMed:8161529, RESID:AA0269, UniMod:421]
subset	PSI-MOD-slim
synonym	"®-2-amino-3-disulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-disulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-hydrodisulfidopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-hydropersulfidopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-persulfhydrylpropanoic acid" EXACT RESID-alternate []
synonym	"3-(thiosulfeno)-alanine" EXACT RESID-alternate []
synonym	"3-disulfanylalanine" EXACT RESID-alternate []
synonym	"ACT_SITE Cysteine persulfide intermediate" EXACT UniProt-feature []
synonym	"L-cysteine persulfide" EXACT RESID-name []
synonym	"MOD_RES Cysteine persulfide" EXACT UniProt-feature []
synonym	"persulfide" RELATED UniMod-description []
synonym	"S-mercaptocysteine" EXACT RESID-alternate []
synonym	"S-sulfanylcysteine" EXACT RESID-alternate []
synonym	"Sulfide" RELATED PSI-MS-label []
synonym	"thiocysteine" EXACT RESID-alternate []
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 1"
xref	DiffMono: "31.972071"
xref	Formula: "C 3 H 5 N 1 O 1 S 2"
xref	MassAvg: "135.20"
xref	MassMono: "134.981256"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01886 thiolated residue ! thiolated residue

2.275. MOD:00275 3'-(1'-L-histidyl)-L-tyrosine

Table 277. Term [MOD:00275]
id	MOD:00275
name	3'-(1'-L-histidyl)-L-tyrosine
def	"A protein modification that effectively cross-links an L-histidine residue and an L-tyrosine residue by a carbon-nitrogen bond to form 3'-(1'-L-histidyl)-L-tyrosine." [ChEBI:19837, PubMed:10338009, RESID:AA0270]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-[1-(5-[(2S)-2-amino-2-carboxyethyl]-2-hydroxyphenyl)-1H-imidazol-4-yl]propanoic acid" EXACT RESID-systematic []
synonym	"3'-(1'-L-histidyl)-L-tyrosine" EXACT RESID-name []
synonym	"3'-(N(epsilon)-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"3'-(N1'-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"3'-(tau-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"3'-(tele-histidyl)tyrosine" EXACT RESID-alternate []
synonym	"CROSSLNK 1'-histidyl-3'-tyrosine (His-Tyr)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 15 H 14 N 4 O 3"
xref	MassAvg: "298.30"
xref	MassMono: "298.106590"
xref	Origin: "H, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.276. MOD:00276 heme P460-bis-L-cysteine-L-lysine

Table 278. Term [MOD:00276]
id	MOD:00276
name	heme P460-bis-L-cysteine-L-lysine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues, a lysine residue, and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:12709052, PubMed:9237682, RESID:AA0271]
comment	Cross-link 3.
synonym	"(19S,20S)-[7,12-bis((S)-1-[(®-2-amino-2-carboxy)ethylsulfanyl]ethyl)-20-([(S)-5-amino-5-carboxypentyl]amino)-3,8,13,17-tetramethyl-21H,23H-19,20-dihydroporphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via 3 links)" EXACT UniProt-feature []
synonym	"bis(S-cysteinyl)-N6-lysino-heme" EXACT RESID-alternate []
synonym	"heme P460-bis-L-cysteine-L-lysine" EXACT RESID-name []
xref	DiffAvg: "614.48"
xref	DiffFormula: "C 34 Fe 1 H 30 N 4 O 4 S 0"
xref	DiffMono: "614.161643"
xref	Formula: "C 46 Fe 1 H 52 N 8 O 7 S 2"
xref	MassAvg: "948.94"
xref	MassMono: "948.274976"
xref	Origin: "C, C, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.277. MOD:00277 5-methyl-L-arginine

Table 279. Term [MOD:00277]
id	MOD:00277
name	5-methyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to 5-methyl-L-arginine." [PubMed:10660523, PubMed:11875433, PubMed:9367957, RESID:AA0272]
synonym	"(2S,5S)-2-amino-5-carbamimidamidohexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-guanidinohexanoic acid" EXACT RESID-alternate []
synonym	"4-methylarginine" RELATED RESID-misnomer []
synonym	"5-methyl-L-arginine" EXACT RESID-name []
synonym	"5-methylated L-arginine" EXACT PSI-MOD-alternate []
synonym	"C5Me1Arg" EXACT PSI-MOD-label []
synonym	"delta-methylarginine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES 5-methylarginine" EXACT UniProt-feature []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00414 monomethylated L-arginine ! monomethylated L-arginine
is_a	MOD:00656 C-methylated residue ! C-methylated residue

2.278. MOD:00278 2-methyl-L-glutamine

Table 280. Term [MOD:00278]
id	MOD:00278
name	2-methyl-L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to 2-methyl-L-glutamine." [PubMed:10660523, PubMed:11875433, PubMed:9367957, RESID:AA0273]
synonym	"(S)-2-amino-2-methylpentanediamic acid" EXACT RESID-systematic []
synonym	"2-methyl-L-glutamine" EXACT RESID-name []
synonym	"2-methylated L-glutamine" EXACT PSI-MOD-alternate []
synonym	"2-methylglutamine" EXACT RESID-alternate []
synonym	"alpha-methylglutamine" EXACT RESID-alternate []
synonym	"C2MeGln" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES 2-methylglutamine" EXACT UniProt-feature []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 10 N 2 O 2"
xref	MassAvg: "142.16"
xref	MassMono: "142.074228"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00656 C-methylated residue ! C-methylated residue
is_a	MOD:00722 monomethylated L-glutamine ! monomethylated L-glutamine

2.279. MOD:00279 N-pyruvic acid 2-iminyl-L-cysteine

Table 281. Term [MOD:00279]
id	MOD:00279
name	N-pyruvic acid 2-iminyl-L-cysteine
def	"A protein modification that effectively converts an Lcysteline residue to N-pyruvic acid 2-iminyl-L-cysteine." [PubMed:1388164, RESID:AA0274, UniMod:422#C]
subset	PSI-MOD-slim
synonym	"®-2-(1-carboxy-2-sulfanylethanimino)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N-pyruvate 2-iminyl-cysteine" EXACT UniProt-feature []
synonym	"N-pyruvic acid 2-iminyl" RELATED UniMod-description []
synonym	"N-pyruvic acid 2-iminyl-L-cysteine" EXACT RESID-name []
synonym	"PyruvicAcidIminyl" RELATED PSI-MS-label []
xref	DiffAvg: "70.05"
xref	DiffFormula: "C 3 H 2 N 0 O 2 S 0"
xref	DiffMono: "70.005479"
xref	Formula: "C 6 H 8 N 1 O 3 S 1"
xref	MassAvg: "174.19"
xref	MassMono: "174.022489"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01170 pyruvic acid iminylated residue ! pyruvic acid iminylated residue

2.280. MOD:00280 N-pyruvic acid 2-iminyl-L-valine

Table 282. Term [MOD:00280]
id	MOD:00280
name	N-pyruvic acid 2-iminyl-L-valine
def	"A protein modification that effectively converts an L-valine residue to N-pyruvic acid 2-iminyl-L-valine." [PubMed:2071591, RESID:AA0275, UniMod:422#V]
subset	PSI-MOD-slim
synonym	"(S)-2-(1-carboxy-2-methylpropanimino)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N-pyruvate 2-iminyl-valine" EXACT UniProt-feature []
synonym	"N-pyruvic acid 2-iminyl" RELATED UniMod-description []
synonym	"N-pyruvic acid 2-iminyl-L-valine" EXACT RESID-name []
synonym	"PyruvicAcidIminyl" RELATED PSI-MS-label []
xref	DiffAvg: "70.05"
xref	DiffFormula: "C 3 H 2 N 0 O 2"
xref	DiffMono: "70.005479"
xref	Formula: "C 8 H 12 N 1 O 3"
xref	MassAvg: "170.19"
xref	MassMono: "170.081718"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01170 pyruvic acid iminylated residue ! pyruvic acid iminylated residue

2.281. MOD:00281 3'-heme-L-histidine

Table 283. Term [MOD:00281]
id	MOD:00281
name	3'-heme-L-histidine
def	"A protein modification that effectively results from forming an adduct between the pros nitrogen of a histidine residue and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:12119398, PubMed:12429096, PubMed:12486054, PubMed:9712585, RESID:AA0276]
synonym	"2-[1-(N3'-histidyl)ethyl]protoporphyrin IX" EXACT RESID-alternate []
synonym	"3'-heme-L-histidine" EXACT RESID-name []
synonym	"[7-ethenyl-12-((S)-1-[(®-2-amino-2-carboxyethyl)-3H-imidazol-3-yl]ethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via pros nitrogen)" EXACT UniProt-feature []
synonym	"N(delta)-histidyl heme" EXACT RESID-alternate []
synonym	"N(pi)-histidyl heme" EXACT RESID-alternate []
synonym	"N3'-histidyl heme" EXACT RESID-alternate []
synonym	"pros-histidyl heme" EXACT RESID-alternate []
xref	DiffAvg: "616.50"
xref	DiffFormula: "C 34 Fe 1 H 32 N 4 O 4"
xref	DiffMono: "616.177293"
xref	Formula: "C 40 Fe 1 H 39 N 7 O 5"
xref	MassAvg: "753.64"
xref	MassMono: "753.236205"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.282. MOD:00282 S-selenyl-L-cysteine

Table 284. Term [MOD:00282]
id	MOD:00282
name	S-selenyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-selenyl-L-cysteine." [PubMed:10430865, PubMed:10966817, PubMed:11827487, PubMed:12716131, PubMed:14594807, RESID:AA0277, UniMod:423#C]
synonym	"®-2-amino-3-(selanylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-hydroselenosulfidopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-hydroselenylsulfidopropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-hydroselenylthiopropanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE S-selanylcysteine intermediate" EXACT UniProt-feature []
synonym	"cysteine perselenide" RELATED RESID-misnomer []
synonym	"Delta:Se(1)" RELATED PSI-MS-label []
synonym	"MOD_RES S-selanylcysteine" EXACT UniProt-feature []
synonym	"S-selanyl-L-cysteine" EXACT RESID-name []
synonym	"S-selanylcysteine" EXACT RESID-alternate []
synonym	"S-selenylcysteine" EXACT RESID-alternate []
synonym	"selenyl" RELATED UniMod-description []
xref	DiffAvg: "78.97"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S 0 Se 1"
xref	DiffMono: "79.916521"
xref	Formula: "C 3 H 5 N 1 O 1 S 1 Se 1"
xref	MassAvg: "182.11"
xref	MassMono: "182.925706"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00745 selenium containing residue ! selenium containing residue
is_a	MOD:00778 residues isobaric at 182.9-183.0 Da ! residues isobaric at 182.9-183.0 Da
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.283. MOD:00283 N6-propylamino-poly(propylmethylamino)-propyldimethylamine-L-lysine

Table 285. Term [MOD:00283]
id	MOD:00283
name	N6-propylamino-poly(propylmethylamino)-propyldimethylamine-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to an N6-propylamino-poly(propylmethylamino)-propyldimethylamine-L-lysine." [PubMed:10550045, PubMed:11349130, RESID:AA0278]
synonym	"(alpha)- ([([(5S)-5-amino-5-carboxypentyl]amino)propyl][(methyl)amino])-(omega)-methyl poly[propane-1,3-diyl(methylimino)]" EXACT RESID-systematic []
synonym	"lysine derivative Lys(x)" EXACT RESID-alternate []
synonym	"MOD_RES N6-poly(methylaminopropyl)lysine" EXACT UniProt-feature []
synonym	"N6-[3-([(omega)-(dimethyl)aminopropyl-poly(3-[methylamino]propyl)]amino)propyl]lysine" EXACT RESID-alternate []
synonym	"N6-propylamino-poly(propylmethylamino)-propyldimethylamine-L-lysine" EXACT RESID-name []
synonym	"silaffin polycationic lysine derivative" EXACT RESID-alternate []
xref	DiffAvg: "426.74"
xref	DiffFormula: "C 24 H 54 N 6 O 0"
xref	DiffMono: "426.440996"
xref	Formula: "C 30 H 66 N 8 O 1"
xref	MassAvg: "554.91"
xref	MassMono: "554.535959"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.284. MOD:00284 dihydroxyheme-L-aspartate ester-L-glutamate ester

Table 286. Term [MOD:00284]
id	MOD:00284
name	dihydroxyheme-L-aspartate ester-L-glutamate ester
def	"A protein modification that effectively results from forming an adduct between an aspartic acid residue, a glutamic acid residue, and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:10447690, RESID:AA0279]
comment	Cross-link 2.
synonym	"1,5-bishydroxymethyl protoporphyrin IX 1-glutamate ester 5-aspartate ester" EXACT RESID-alternate []
synonym	"[13-[(S)-(4-amino-4-carboxy)butanoyloxymethyl]-3-[(S)-(3-amino-3-carboxy)propanoyloxymethyl]-7,12-diethenyl-8,17-dimethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"dihydroxyheme-L-aspartate ester-L-glutamate ester" EXACT RESID-name []
synonym	"peroxidase heme cofactor" EXACT RESID-alternate []
xref	DiffAvg: "612.47"
xref	DiffFormula: "C 34 Fe 1 H 28 N 4 O 4"
xref	DiffMono: "612.145993"
xref	Formula: "C 43 Fe 1 H 40 N 6 O 10"
xref	MassAvg: "856.67"
xref	MassMono: "856.215529"
xref	Origin: "D, E"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.285. MOD:00285 dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfonium

Table 287. Term [MOD:00285]
id	MOD:00285
name	dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfonium
def	"A protein modification that effectively results from forming an adduct between an aspartic acid residue, a glutamic acid residue, a methionine residue (forming a sulfonium ether), and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:10447690, PubMed:10480885, PubMed:1320128, PubMed:7840679, RESID:AA0280]
comment	Cross-link 3.
synonym	"1,5-bishydroxymethyl protoporphyrin IX 1-glutamate ester 5-aspartate ester 2-methionine sulfonium" EXACT RESID-alternate []
synonym	"[13-[(S)-(4-amino-4-carboxy)butanoyloxymethyl]-3-[(S)-(3-amino-3-carboxy)propanoyloxymethyl]-12-[(S)-(3-amino-3-carboxy)propylsulfoniumethyl]-7-ethenyl-8,17-dimethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via 3 links)" EXACT UniProt-feature []
synonym	"dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfonium" EXACT RESID-name []
synonym	"myeloperoxidase heme cofactor" EXACT RESID-alternate []
xref	DiffAvg: "613.47"
xref	DiffFormula: "C 34 Fe 1 H 29 N 4 O 4 S 0"
xref	DiffMono: "613.153269"
xref	FormalCharge: "1+"
xref	Formula: "C 48 Fe 1 H 50 N 7 O 11 S 1"
xref	MassAvg: "988.87"
xref	MassMono: "988.263290"
xref	Origin: "D, E, M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.286. MOD:00286 L-cysteinyl molybdenum bis(molybdopterin guanine dinucleotide)

Table 288. Term [MOD:00286]
id	MOD:00286
name	L-cysteinyl molybdenum bis(molybdopterin guanine dinucleotide)
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteinyl molybdenum bis(molybdopterin guanine dinucleotide)." [RESID:AA0281, UniMod:424#C]
synonym	"2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotide" EXACT RESID-alternate []
synonym	"bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-cystein-S-yl-molybdenum" EXACT RESID-systematic []
synonym	"L-cysteinyl molybdenum bis(molybdopterin guanine dinucleotide)" EXACT RESID-name []
synonym	"molybdenum bis(molybdopterin guanine dinucleotide)" RELATED UniMod-description []
synonym	"MolybdopterinGD" RELATED PSI-MS-label []
xref	DiffAvg: "1572.02"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 26 P 4 S 4"
xref	DiffMono: "1572.985775"
xref	Formula: "C 43 H 52 Mo 1 N 21 O 27 P 4 S 5"
xref	MassAvg: "1675.15"
xref	MassMono: "1675.994960"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01167 molybdopterin guanine dinucleotide ! molybdopterin guanine dinucleotide

2.287. MOD:00287 (2S,3R,4S)-3,4-dihydroxyproline

Table 289. Term [MOD:00287]
id	MOD:00287
name	(2S,3R,4S)-3,4-dihydroxyproline
def	"A protein modification that effectively converts an L-proline residue to a (2S,3R,4S)-3,4-dihydroxyproline." [DeltaMass:0, PubMed:12686488, RESID:AA0282, UniMod:425#P]
comment	From DeltaMass: Average Mass: 32.
synonym	"(2S,3R,4S)-3,4-dihydroxyproline" EXACT RESID-name []
synonym	"(2S,3R,4S)-3,4-dihydroxypyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"2,3-trans-3,4-cis-3,4-dihydroxy-L-proline" EXACT RESID-alternate []
synonym	"2-alpha-3-beta-4-beta-3,4-dihydroxyproline" EXACT RESID-alternate []
synonym	"3,4-dihydroxylated L-proline" EXACT PSI-MOD-alternate []
synonym	"3,4-Dihydroxylation (of Proline)" EXACT DeltaMass-label []
synonym	"34Hy2Pro" EXACT PSI-MOD-label []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"MOD_RES (3R,4S)-3,4-dihydroxyproline" EXACT UniProt-feature []
synonym	"trans-2,3-cis-3,4-dihydroxy-L-proline" EXACT RESID-alternate []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00866 dihydroxylated proline ! dihydroxylated proline

2.288. MOD:00288 pyrroloquinoline quinone

Table 290. Term [MOD:00288]
id	MOD:00288
name	pyrroloquinoline quinone
def	"A protein modification that effectively doubly cross-links an L-glutamic acid residue and an L-tyrosine residue with a carbon-carbon bond and a carbon-nitrogen bond to form pyrroloquinoline quinone." [ChEBI:18315, PubMed:1310505, PubMed:7665488, RESID:AA0283]
comment	Cross-link 2.
synonym	"2,4,6-tricarboxylic-pyrrolo[2,3-5,6]quinoline 8,9-quinone" EXACT RESID-alternate []
synonym	"2,7,9-tricarboxy-1H-pyrrolo(2,3-f)quinoline-4,5-dione" EXACT RESID-alternate []
synonym	"4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-5,6]quinoline-2,7,9-tricarboxylic acid" EXACT RESID-systematic []
synonym	"coenzyme PQQ" EXACT RESID-alternate []
synonym	"CROSSLNK Pyrroloquinoline quinone (Glu-Tyr)" EXACT UniProt-feature []
synonym	"methoxatin" EXACT RESID-alternate []
synonym	"pyrroloquinoline quinone" EXACT RESID-name []
xref	DiffAvg: "37.92"
xref	DiffFormula: "C 0 H -10 N 0 O 3"
xref	DiffMono: "37.906494"
xref	Formula: "C 14 H 6 N 2 O 8"
xref	MassAvg: "330.21"
xref	MassMono: "330.012415"
xref	Origin: "E, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.289. MOD:00289 tris-L-cysteinyl L-N1'-histidino tetrairon tetrasulfide

Table 291. Term [MOD:00289]
id	MOD:00289
name	tris-L-cysteinyl L-N1'-histidino tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-histidine residue and a four-iron four-sulfur cluster to tris-L-cysteinyl L-N1'-histidino tetrairon tetrasulfide." [PubMed:9836629, RESID:AA0284]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (4Fe-4S); via tele nitrogen" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfidotris(S-cysteinyliron)(N1'-histidinoiron)" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl L-N1'-histidino tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 15 Fe 4 H 18 N 6 O 4 S 7"
xref	MassAvg: "794.15"
xref	MassMono: "793.684297"
xref	Origin: "C, C, C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.290. MOD:00290 tris-L-cysteinyl L-N3'-histidino tetrairon tetrasulfide

Table 292. Term [MOD:00290]
id	MOD:00290
name	tris-L-cysteinyl L-N3'-histidino tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-histidine residue and a four-iron four-sulfur cluster to tris-L-cysteinyl L-N3'-histidino tetrairon tetrasulfide." [PubMed:7854413, RESID:AA0285]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (4Fe-4S); via pros nitrogen" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfidotris(S-cysteinyliron)(N3'-histidinoiron)" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl L-N3'-histidino tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 15 Fe 4 H 18 N 6 O 4 S 7"
xref	MassAvg: "794.15"
xref	MassMono: "793.684297"
xref	Origin: "C, C, C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.291. MOD:00291 tris-L-cysteinyl L-aspartato tetrairon tetrasulfide

Table 293. Term [MOD:00291]
id	MOD:00291
name	tris-L-cysteinyl L-aspartato tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-aspartic acid residue and a four-iron four-sulfur cluster to tris-L-cysteinyl L-aspartato tetrairon tetrasulfide." [PubMed:7819255, PubMed:9283079, RESID:AA0286]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfidotris(S-cysteinyliron)(O4-aspartatoiron)" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl L-aspartato tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 13 Fe 4 H 16 N 4 O 6 S 7"
xref	MassAvg: "772.09"
xref	MassMono: "771.652328"
xref	Origin: "C, C, C, D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.292. MOD:00292 N6-pyruvic acid 2-iminyl-L-lysine

Table 294. Term [MOD:00292]
id	MOD:00292
name	N6-pyruvic acid 2-iminyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-pyruvic acid 2-iminyl-L-lysine." [PubMed:1463470, PubMed:7853400, PubMed:9047371, RESID:AA0287, UniMod:422#K]
synonym	"(2S)-2-amino-6-([1-carboxyethylidene]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE Schiff-base intermediate with substrate" EXACT UniProt-feature []
synonym	"N-pyruvic acid 2-iminyl" RELATED UniMod-description []
synonym	"N6-pyruvic acid 2-iminyl-L-lysine" EXACT RESID-name []
synonym	"PyruvicAcidIminyl" RELATED PSI-MS-label []
xref	DiffAvg: "70.05"
xref	DiffFormula: "C 3 H 2 N 0 O 2"
xref	DiffMono: "70.005479"
xref	Formula: "C 9 H 14 N 2 O 3"
xref	MassAvg: "198.22"
xref	MassMono: "198.100442"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01170 pyruvic acid iminylated residue ! pyruvic acid iminylated residue

2.293. MOD:00293 tris-L-cysteinyl L-serinyl tetrairon tetrasulfide

Table 295. Term [MOD:00293]
id	MOD:00293
name	tris-L-cysteinyl L-serinyl tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-serine residue and a four-iron four-sulfur cluster to tris-L-cysteinyl L-serinyl tetrairon tetrasulfide." [RESID:AA0288]
comment	Cross-link 4.
synonym	"tetra-mu3-sulfidotris(S-cysteinyliron)(O3-serinyliron)" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl L-serinyl tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 12 Fe 4 H 16 N 4 O 5 S 7"
xref	MassAvg: "744.08"
xref	MassMono: "743.657414"
xref	Origin: "C, C, C, S"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.294. MOD:00294 bis-L-cysteinyl L-N3'-histidino L-serinyl tetrairon tetrasulfide

Table 296. Term [MOD:00294]
id	MOD:00294
name	bis-L-cysteinyl L-N3'-histidino L-serinyl tetrairon tetrasulfide
def	"A protein modification that effectively converts two L-cysteine residues, an L-histidine residues, an L-serine residue and a four-iron four-sulfur cluster to bis-L-cysteinyl L-N3'-histidino L-serinyl tetrairon tetrasulfide." [RESID:AA0289]
comment	Cross-link 4.
synonym	"bis-L-cysteinyl L-N3'-histidino L-serinyl tetrairon tetrasulfide" EXACT RESID-name []
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (4Fe-4S); via pros nitrogen" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfidobis(S-cysteinyliron)(N3'-histidinoiron)(O3-serinyliron)" EXACT RESID-systematic []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.597831"
xref	FormalCharge: "2-"
xref	Formula: "C 15 Fe 4 H 18 N 6 O 5 S 6"
xref	MassAvg: "778.09"
xref	MassMono: "777.707141"
xref	Origin: "C, C, H, S"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.295. MOD:00295 O-octanoyl-L-serine

Table 297. Term [MOD:00295]
id	MOD:00295
name	O-octanoyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-octanoyl-L-serine." [PubMed:10604470, PubMed:12716131, RESID:AA0290, UniMod:426#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(octanoyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"L-serine octanoate ester" EXACT RESID-alternate []
synonym	"LIPID O-octanoyl serine" EXACT UniProt-feature []
synonym	"O-octanoyl-L-serine" EXACT RESID-name []
synonym	"O-octanoylated L-serine" EXACT PSI-MOD-alternate []
synonym	"O3-octanoyl-L-serine" EXACT RESID-alternate []
synonym	"Octanoyl" RELATED PSI-MS-label []
synonym	"octanoyl" RELATED UniMod-description []
synonym	"OOctSer" EXACT PSI-MOD-label []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1"
xref	DiffMono: "126.104465"
xref	Formula: "C 11 H 19 N 1 O 3"
xref	MassAvg: "213.28"
xref	MassMono: "213.136493"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00669 O-octanoylated residue ! O-octanoylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.296. MOD:00296 O-D-glucuronosyl-L-serine

Table 298. Term [MOD:00296]
id	MOD:00296
name	O-D-glucuronosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-D-glucuronosyl-L-serine." [PubMed:10858503, PubMed:12716131, PubMed:7398618, RESID:AA0291, UniMod:54#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(beta-D-glucopyranuronosyl)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GlcA)" EXACT UniProt-feature []
synonym	"Glucuronyl" RELATED PSI-MS-label []
synonym	"N-glucuronylation" RELATED UniMod-description []
synonym	"O-D-glucuronosyl-L-serine" EXACT RESID-name []
synonym	"O3-D-glucuronosyl-L-serine" EXACT RESID-alternate []
xref	DiffAvg: "176.12"
xref	DiffFormula: "C 6 H 8 N 0 O 6"
xref	DiffMono: "176.032088"
xref	Formula: "C 9 H 13 N 1 O 8"
xref	MassAvg: "263.20"
xref	MassMono: "263.064116"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00447 N-glucuronylated residue ! N-glucuronylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.297. MOD:00297 tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

Table 299. Term [MOD:00297]
id	MOD:00297
name	tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide
def	"A protein modification that effectively converts four L-cysteine residues, two L-glutamic acid residues, an L-histidine residue and a three-iron three-sulfur three-oxygen cluster to tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide." [RESID:AA0292]
comment	Cross-link 7; secondary to RESID:AA0269. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"carbon monoxide dehydrogenase nickel-iron cofactor" EXACT RESID-alternate []
synonym	"hybrid nickel-triiron cluster" EXACT RESID-alternate []
synonym	"mu-1:2kappaO-oxido-mu-1:3kappaO-oxido-mu-2:4kappaO-oxido-mu-3:4kappaS-sulfido-mu3-2:3:4kappaS-sulfido-S-cysteinyl-N1'-histidino-O5-glutamato 1-iron-S5-cysteine persulfido-O5-glutamato 2-nickel-3,4-bis-(S-cysteinyl iron)" EXACT RESID-systematic []
synonym	"Ni-3Fe-2S-3O cluster" EXACT RESID-alternate []
synonym	"tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide" EXACT RESID-name []
xref	DiffAvg: "363.35"
xref	DiffFormula: "C 0 Fe 3 H -7 N 0 Ni 1 O 3 S 3"
xref	DiffMono: "362.586337"
xref	Formula: "C 28 Fe 3 H 34 N 9 Ni 1 O 14 S 7"
xref	MassAvg: "1171.28"
xref	MassMono: "1169.767174"
xref	Origin: "C, C, C, C, E, E, H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00741 nickel containing modified residue ! nickel containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.298. MOD:00298 tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide

Table 300. Term [MOD:00298]
id	MOD:00298
name	tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide
def	"A protein modification that effectively converts four L-cysteine residues, an L-glutamic acid residue, an L-histidine residue, an L-serine residue and a one-nickel three-iron three-sulfur three-oxygen cluster to tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide." [PubMed:2550436, RESID:AA0293]
comment	Cross-link 7; secondary to RESID:AA0269. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"carbon monoxide dehydrogenase nickel-iron cofactor" EXACT RESID-alternate []
synonym	"hybrid nickel-triiron cluster" EXACT RESID-alternate []
synonym	"mu-1:2kappaO-oxido-mu-1:3kappaO-oxido-mu-2:4kappaO-oxido-mu-3:4kappaS-sulfido-mu3-2:3:4kappaS-sulfido-S-cysteinyl-N1'-histidino-O5-glutamato 1-iron-S5-cysteine persulfido-O3-serinyl 2-nickel-3,4-bis-(S-cysteinyl iron)" EXACT RESID-systematic []
synonym	"Ni-3Fe-2S-3O cluster" EXACT RESID-alternate []
synonym	"tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide" EXACT RESID-name []
xref	DiffAvg: "363.35"
xref	DiffFormula: "C 0 Fe 3 H -7 N 0 Ni 1 O 3 S 3"
xref	DiffMono: "362.586337"
xref	Formula: "C 26 Fe 3 H 32 N 9 Ni 1 O 13 S 7"
xref	MassAvg: "1129.24"
xref	MassMono: "1127.756609"
xref	Origin: "C, C, C, C, E, H, S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00741 nickel containing modified residue ! nickel containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.299. MOD:00299 N6-(L-isoaspartyl)-L-lysine (Asn)

Table 301. Term [MOD:00299]
id	MOD:00299
name	N6-(L-isoaspartyl)-L-lysine (Asn)
def	"A protein modification that effectively crosslinks an L-asparagine residue and an L-lysine residue by an isopeptide bond with the formation of N6-(L-isoaspartyl)-L-lysine and the release of ammonia." [ChEBI:21862, DeltaMass:0, PubMed:11000116, PubMed:6503713, RESID:AA0294]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(3S)-3-amino-3-carboxypropanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"beta-(N6-lysyl)aspartyl acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl lysine isopeptide (Lys-Asn)" EXACT UniProt-feature []
synonym	"isoaspartyl N6-lysine" EXACT RESID-alternate []
synonym	"N(epsilon)-(beta-aspartyl)lysine" EXACT RESID-alternate []
synonym	"N-(beta-Aspartyl)-Lysine (Crosslink)" EXACT DeltaMass-label []
synonym	"N6-(L-isoaspartyl)-L-lysine" EXACT RESID-name []
synonym	"XLNK-4Asp-N6Lys(Asn)" EXACT PSI-MOD-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 10 H 15 N 3 O 3"
xref	MassAvg: "225.25"
xref	MassMono: "225.111341"
xref	Origin: "K, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia
is_a	MOD:01929 N6-(L-isoaspartyl)-L-lysine ! N6-(L-isoaspartyl)-L-lysine

2.300. MOD:00300 L-glutamyl-5-poly(ADP-ribose)

Table 302. Term [MOD:00300]
id	MOD:00300
name	L-glutamyl-5-poly(ADP-ribose)
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose)." [DeltaMass:0, PubMed:11246023, PubMed:15842200, PubMed:8533153, RESID:AA0295, UniMod:213#E]
synonym	"(S)-2-amino-5-poly[2'-adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with 1alpha-D-ribofuranosyl]oxy-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"ADP Ribose addition" RELATED UniMod-description []
synonym	"ADP-Ribosyl" RELATED PSI-MS-label []
synonym	"L-glutamyl-5-poly(ADP-ribose)" EXACT RESID-name []
synonym	"L-isoglutamyl-poly(ADP-ribose)" EXACT RESID-alternate []
synonym	"MOD_RES PolyADP-ribosyl glutamic acid" EXACT UniProt-feature []
synonym	"O-ADP-ribosylation (on Glutamate or C terminus)" EXACT DeltaMass-label []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 20 H 28 N 6 O 16 P 2"
xref	MassAvg: "670.42"
xref	MassMono: "670.103702"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.301. MOD:00301 O-(N-acetylglucosamine-1-phosphoryl)-L-serine

Table 303. Term [MOD:00301]
id	MOD:00301
name	O-(N-acetylglucosamine-1-phosphoryl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(N-acetylglucosamine-1-phosphoryl)-L-serine." [DeltaMass:0, PubMed:6438439, PubMed:6993483, PubMed:8631906, RESID:AA0296, UniMod:428]
synonym	"(2S)-2-amino-3-[([(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)oxy][hydroxy]phosphoryl)oxy]propanoic acid" EXACT RESID-systematic []
synonym	"N-acetylglucosamine-1-phosphoryl" RELATED UniMod-description []
synonym	"O-(N-acetylglucosamine-1-phosphoryl)-L-serine" EXACT RESID-name []
synonym	"O-beta(N-acetyl-glucosamine-alpha1-phosphate)serine" EXACT RESID-alternate []
synonym	"O-GlcNAc-1-phosphorylation (of Serine)" EXACT DeltaMass-label []
synonym	"O3-(N-acetylglucosamine-1-phosphoryl)-L-serine" EXACT RESID-alternate []
synonym	"O3-L-serine 2-(acetylamino)-2-deoxy-D-glucopyranose 1-phosphodiester" EXACT RESID-alternate []
synonym	"PhosphoHexNAc" RELATED PSI-MS-label []
xref	DiffAvg: "283.17"
xref	DiffFormula: "C 8 H 14 N 1 O 8 P 1"
xref	DiffMono: "283.045703"
xref	Formula: "C 11 H 19 N 2 O 10 P 1"
xref	MassAvg: "370.25"
xref	MassMono: "370.077731"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01804 glycosylphosphorylated residue ! glycosylphosphorylated residue

2.302. MOD:00302 O-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine

Table 304. Term [MOD:00302]
id	MOD:00302
name	O-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine." [PubMed:10037765, PubMed:15649890, RESID:AA0297, UniMod:429]
synonym	"O-(alpha-D-mannosyl-1-phosphoryl)-L-serine" EXACT RESID-alternate []
synonym	"O-(D-mannose-1-phosphoryl)-L-serine" EXACT RESID-name []
synonym	"O-[alpha-D-mannopyranosyloxy(hydroxy)phosphoryl]-L-serine" EXACT RESID-systematic []
synonym	"O3-(D-mannose-1-phosphoryl)-L-serine" EXACT RESID-alternate []
synonym	"O3-L-serine alpha-D-mannopyranose 1-phosphodiester" EXACT RESID-alternate []
synonym	"phosphoglycosyl-D-mannose-1-phosphoryl" RELATED UniMod-description []
synonym	"PhosphoHex" RELATED PSI-MS-label []
xref	DiffAvg: "242.12"
xref	DiffFormula: "C 6 H 11 N 0 O 8 P 1"
xref	DiffMono: "242.019154"
xref	Formula: "C 9 H 16 N 1 O 10 P 1"
xref	MassAvg: "329.20"
xref	MassMono: "329.051182"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01804 glycosylphosphorylated residue ! glycosylphosphorylated residue

2.303. MOD:00303 heptakis-L-histidino tetracopper mu4-sulfide hydroxide

Table 305. Term [MOD:00303]
id	MOD:00303
name	heptakis-L-histidino tetracopper mu4-sulfide hydroxide
def	"A protein modification that effectively converts seven L-histidinine residues and a four-copper one-sulfur one-hydroxide cluster to heptakis-L-histidino tetracopper mu4-sulfide hydroxide." [PubMed:11024061, PubMed:11041839, RESID:AA0298]
comment	Cross-link 7.
synonym	"heptakis-L-histidino tetracopper mu4-sulfide hydroxide" EXACT RESID-name []
synonym	"mu4-sulfido bis(bis-N1'-histidino copper)(N1'-histidino-N3'-histidino copper)(N3'-histidino hydroxide copper)" EXACT RESID-systematic []
synonym	"nitrous oxide reductase nosZ CuZ cluster" EXACT RESID-alternate []
synonym	"pentakis-L-N1'-histidino-bis-L-N3'-histidino tetracopper sulfide hydroxide" EXACT RESID-alternate []
xref	DiffAvg: "296.19"
xref	DiffFormula: "C 0 Cu 4 H -6 N 0 O 1 S 1"
xref	DiffMono: "293.638425"
xref	Formula: "C 42 Cu 4 H 43 N 21 O 8 S 1"
xref	MassAvg: "1256.19"
xref	MassMono: "1253.050808"
xref	Origin: "H, H, H, H, H, H, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.304. MOD:00304 L-leucine methyl ester

Table 306. Term [MOD:00304]
id	MOD:00304
name	L-leucine methyl ester
def	"A protein modification that effectively converts an L-leucine residue to L-leucine methyl ester." [PubMed:10191253, PubMed:11875433, PubMed:8206937, RESID:AA0299, UniMod:34#C-term]
comment	incidental to RESID:AA0039
subset	PSI-MOD-slim
synonym	"2-amino-4-methylpentanoic methyl ester" EXACT RESID-alternate []
synonym	"alpha-aminoisocaproic methyl ester" EXACT RESID-alternate []
synonym	"L-leucine methyl ester" EXACT RESID-name []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methyl (2S)-2-amino-4-methylpentanoate" EXACT RESID-systematic []
synonym	"methyl esterified L-leucine" EXACT PSI-MOD-alternate []
synonym	"methyl L-leucinate" EXACT RESID-alternate []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Leucine methyl ester" EXACT UniProt-feature []
synonym	"OMeLeu" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 1 O 2"
xref	MassAvg: "144.19"
xref	MassMono: "144.102454"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00662 methylated leucine ! methylated leucine
is_a	MOD:01689 alpha-carboxyl methylated residue ! alpha-carboxyl methylated residue

2.305. MOD:00305 hexakis-L-cysteinyl L-serinyl octairon heptasulfide

Table 307. Term [MOD:00305]
id	MOD:00305
name	hexakis-L-cysteinyl L-serinyl octairon heptasulfide
def	"A protein modification that effectively converts six L-cysteine residues, an L-serine residue and a eight-iron seven-sulfur cluster to hexakis-L-cysteinyl L-serinyl octairon heptasulfide." [PubMed:10525412, PubMed:12215645, PubMed:9063865, RESID:AA0300]
comment	Cross-link 7; incidental to RESID:AA0141.
synonym	"Cys6Ser-[8Fe7S]" EXACT PSI-MOD-label []
synonym	"hexakis-L-cysteinyl L-serinyl octairon heptasulfide" EXACT RESID-name []
synonym	"METAL Iron-sulfur (8Fe-7S)" EXACT UniProt-feature []
synonym	"nitrogenase P-cluster" EXACT RESID-alternate []
xref	DiffAvg: "663.12"
xref	DiffFormula: "C 0 Fe 8 H -8 N 0 O 0 S 7"
xref	DiffMono: "663.223042"
xref	FormalCharge: "3-"
xref	Formula: "C 21 Fe 8 H 27 N 7 O 8 S 13"
xref	MassAvg: "1369.03"
xref	MassMono: "1368.310179"
xref	Origin: "C, C, C, C, C, C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.306. MOD:00306 residues isobaric at 113.084064 Da

Table 308. Term [MOD:00306]
id	MOD:00306
name	residues isobaric at 113.084064 Da
def	"Natural or modified residues with a mass of 113.084064 Da." [PubMed:10523135, RESID:AA0301]
subset	PSI-MOD-slim
synonym	"L-isoleucine or L-leucine" EXACT RESID-name []
synonym	"Xle" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00569 residues isobaric at a resolution below 0.000001 Da ! residues isobaric at a resolution below 0.000001 Da
is_a	MOD:00624 residues isobaric at 113.0-113.1 Da ! residues isobaric at 113.0-113.1 Da

2.307. MOD:00307 L-aspartimide

Table 309. Term [MOD:00307]
id	MOD:00307
name	L-aspartimide
def	"A protein modification that effectively cyclizes an L-asparagine residue to form a carboxyl-terminal L-aspartimide." [DeltaMass:18, PubMed:12771378, PubMed:2378679, PubMed:7662664, PubMed:7988548, PubMed:9309583, RESID:AA0302, UniMod:23#N]
comment	From DeltaMass: Average Mass: -17 Average Mass Change:-17 References:Clarke, S., Lability of Aspargine and Aspartic Acid Residues in Protein and Peptides, in: Stability of Protein Pharmaceuticals : Chemical and Physical Paths of Protein Degradation, Part A (T.J. Ahern and M.C. Manning, eds.), 1992,Plenum Press, New York, pp.1-29Xie, M.; Vander Velde, D.; Morton, M.; Borchardt, R.T.; Schowen,R.L.: pH-Induced Change in the Rate-Determining Step for the Hydrolysis of the Asp/Asn-Derived Cyclic-Imide Intermediate in Protein Degradation. (1996) J. Am. Chem. Soc. 118: 8955-8956.
synonym	"(3S)-3-amino-2,5-pyrrolidinedione" EXACT RESID-systematic []
synonym	"2-amino-butanimide" EXACT RESID-alternate []
synonym	"alpha-aminosuccinimide" EXACT RESID-alternate []
synonym	"ASI" EXACT RESID-alternate []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"L-2-aminosuccinimide" EXACT RESID-alternate []
synonym	"L-3-aminosuccinimide" RELATED RESID-misnomer []
synonym	"L-asparaginimide" EXACT RESID-alternate []
synonym	"L-aspartimide" EXACT RESID-name []
synonym	"Succinimide formation from asparagine" EXACT DeltaMass-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 4 H 5 N 2 O 2"
xref	MassAvg: "113.10"
xref	MassMono: "113.035102"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00704 dehydrated residue ! dehydrated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.308. MOD:00308 L-glutamimide

Table 310. Term [MOD:00308]
id	MOD:00308
name	L-glutamimide
def	"A protein modification that effectively cyclizes an L-glutamine residue to form a carboxyl-terminal L-glutamimide." [PubMed:12771378, PubMed:14593103, RESID:AA0303, UniMod:23#Q]
synonym	"(3S)-3-aminopiperidine-2,6-dione" EXACT RESID-systematic []
synonym	"2-aminopentanimide" EXACT RESID-alternate []
synonym	"3-amino-2,6-piperidinedione" EXACT RESID-alternate []
synonym	"alpha-aminoglutarimide" EXACT RESID-alternate []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"L-glutamimide" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 7 N 2 O 2"
xref	MassAvg: "127.12"
xref	MassMono: "127.050752"
xref	Origin: "Q"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00704 dehydrated residue ! dehydrated residue
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.309. MOD:00309 L-beta-carboxyaspartic acid

Table 311. Term [MOD:00309]
id	MOD:00309
name	L-beta-carboxyaspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to L-beta-carboxyaspartic acid." [OMSSA:47, PubMed:6390094, PubMed:7138832, PubMed:7457858, PubMed:8135347, RESID:AA0304, UniMod:299#D]
comment	References to this modification as a gamma-carboxylation are in error [JSG].
synonym	"(2S)-2-aminoethane-1,1,2-tricarboxylic acid" EXACT RESID-systematic []
synonym	"2-amino-3-carboxybutanedioic acid" EXACT RESID-alternate []
synonym	"3-carboxy-L-aspartic acid" EXACT RESID-name []
synonym	"3-carboxyaspartic acid" EXACT RESID-alternate []
synonym	"3CbxAsp" EXACT PSI-MOD-label []
synonym	"beta-carboxyaspartic acid" EXACT RESID-alternate []
synonym	"Carboxy" RELATED PSI-MS-label []
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxylation" RELATED UniMod-description []
synonym	"gammacarboxyld" EXACT OMSSA-label []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 5 H 5 N 1 O 5"
xref	MassAvg: "159.10"
xref	MassMono: "159.016772"
xref	Origin: "D"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.310. MOD:00310 N5-methyl-L-arginine

Table 312. Term [MOD:00310]
id	MOD:00310
name	N5-methyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N5-methyl-L-arginine." [PubMed:11875433, PubMed:9792625, PubMed:9873020, RESID:AA0305]
synonym	"(2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic acid" EXACT RESID-systematic []
synonym	"delta-N-methylarginine" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N5-methylarginine" EXACT UniProt-feature []
synonym	"N5-carbamimidoyl-N5-methyl-L-ornithine" EXACT RESID-alternate []
synonym	"N5-methyl-L-arginine" EXACT RESID-name []
synonym	"N5-methylated L-arginine" EXACT PSI-MOD-alternate []
synonym	"N5Me1Arg" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "R"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00414 monomethylated L-arginine ! monomethylated L-arginine
is_a	MOD:00602 N-methylated residue ! N-methylated residue

2.311. MOD:00311 L-cysteine coenzyme A disulfide

Table 313. Term [MOD:00311]
id	MOD:00311
name	L-cysteine coenzyme A disulfide
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine coenzyme A disulfide." [DeltaMass:0, PubMed:1734967, RESID:AA0306, UniMod:281#C]
comment	DeltaMass gives no formula with mass as 454.
synonym	"(2R)-2-amino-3-(2-((3-(((2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino)-1-oxopropyl)amino)ethyl)dithio-propanoic acid 4'-ester with adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate)" EXACT RESID-systematic []
synonym	"coenzyme A L-cysteine mixed disulfide" EXACT RESID-alternate []
synonym	"CoenzymeA" RELATED PSI-MS-label []
synonym	"Cysteine modified Coenzyme A" RELATED UniMod-description []
synonym	"L-cysteine coenzyme A disulfide" EXACT RESID-name []
synonym	"SCoACys" EXACT PSI-MOD-label []
xref	DiffAvg: "765.52"
xref	DiffFormula: "C 21 H 34 N 7 O 16 P 3 S 1"
xref	DiffMono: "765.099559"
xref	Formula: "C 24 H 39 N 8 O 17 P 3 S 2"
xref	MassAvg: "868.66"
xref	MassMono: "868.108744"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.312. MOD:00312 S-myristoyl-L-cysteine

Table 314. Term [MOD:00312]
id	MOD:00312
name	S-myristoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-myristoyl-L-cysteine." [PubMed:10026218, PubMed:10080938, PubMed:8824274, RESID:AA0307, UniMod:45#C]
synonym	"®-2-amino-3-(tetradecanoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"LIPID S-myristoyl cysteine" EXACT UniProt-feature []
synonym	"Myristoyl" RELATED PSI-MS-label []
synonym	"Myristoylation" RELATED UniMod-description []
synonym	"S-(C14:1 aliphatic acyl)cysteine" EXACT PSI-MOD-alternate []
synonym	"S-myristoyl-L-cysteine" EXACT RESID-name []
synonym	"S-myristoylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"SMyrCys" EXACT PSI-MOD-label []
synonym	"tetradecanoate cysteine thioester" EXACT RESID-alternate []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 N 0 O 1 S 0"
xref	DiffMono: "210.198365"
xref	Formula: "C 17 H 31 N 1 O 2 S 1"
xref	MassAvg: "313.50"
xref	MassMono: "313.207550"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00655 S-myristoylated residue ! S-myristoylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.313. MOD:00313 S-palmitoleyl-L-cysteine

Table 315. Term [MOD:00313]
id	MOD:00313
name	S-palmitoleyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-palmitoleyl-L-cysteine." [OMSSA:187, PubMed:8294460, RESID:AA0308, UniMod:431#C]
synonym	"®-2-amino-3-((Z)-9-hexadecenoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"cis-9-hexadecenoate cysteine thioester" EXACT RESID-alternate []
synonym	"mod187" EXACT OMSSA-label []
synonym	"Palmitoleyl" RELATED PSI-MS-label []
synonym	"palmitoleyl" RELATED UniMod-description []
synonym	"S-palmitoleyl-L-cysteine" EXACT RESID-name []
synonym	"S-palmitoleylated L-cysteine" EXACT PSI-MOD-alternate []
synonym	"SPamD1Cys" EXACT PSI-MOD-label []
xref	DiffAvg: "236.40"
xref	DiffFormula: "C 16 H 28 N 0 O 1 S 0"
xref	DiffMono: "236.214016"
xref	Formula: "C 19 H 33 N 1 O 2 S 1"
xref	MassAvg: "339.54"
xref	MassMono: "339.223200"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00672 S-acylated residue ! S-acylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01423 palmitoleylated residue ! palmitoleylated residue

2.314. MOD:00314 glycine cholesterol ester

Table 316. Term [MOD:00314]
id	MOD:00314
name	glycine cholesterol ester
def	"A protein modification that effectively converts a glycine residue to glycine cholesterol ester." [PubMed:11111088, PubMed:8824192, RESID:AA0309, UniMod:432#C-term]
comment	Incidental to RESID:AA0060. UniMod origin corrected [JSG].
subset	PSI-MOD-slim
synonym	"C-cholesterol" RELATED UniMod-interim []
synonym	"cholesterol ester" RELATED UniMod-description []
synonym	"cholesteryl glycinate" EXACT RESID-alternate []
synonym	"glycine cholest-5-en-3beta-ol ester" EXACT RESID-systematic []
synonym	"glycine cholesterol ester" EXACT RESID-name []
synonym	"hedgehog lipophilic adduct" EXACT RESID-alternate []
synonym	"LIPID Cholesterol glycine ester" EXACT UniProt-feature []
xref	DiffAvg: "368.65"
xref	DiffFormula: "C 27 H 44 N 0 O 0"
xref	DiffMono: "368.344301"
xref	Formula: "C 29 H 48 N 1 O 2"
xref	MassAvg: "442.71"
xref	MassMono: "442.368505"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.315. MOD:00315 pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

Table 317. Term [MOD:00315]
id	MOD:00315
name	pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide
def	"A protein modification that effectively converts five L-cysteine residues, an L-histidine residue and a one-nickel four-iron five-sulfur cluster to pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide." [PubMed:11509720, PubMed:2550436, RESID:AA0310]
comment	Cross-link 6.
synonym	"carbon monoxide dehydrogenase nickel-iron cofactor" EXACT RESID-alternate []
synonym	"METAL Nickel-iron-sulfur (Ni-4Fe-5S)" EXACT UniProt-feature []
synonym	"METAL Nickel-iron-sulfur (Ni-4Fe-5S); via tele nitrogen" EXACT UniProt-feature []
synonym	"mu-1:2kappaS-sulfido-mu3-1:3:5kappaS-sulfido-mu3-2:3:4kappaS-sulfido-mu3-2:4:5kappaS-sulfido-mu3-3:4:5kappaS-sulfido-N1'-histidino-S-cysteinyl-1-iron-S-cysteinyl-2-nickel-3,4,5-tris-(S-cysteinyl iron)" EXACT RESID-systematic []
synonym	"Ni-4Fe-5S cluster" EXACT RESID-alternate []
synonym	"pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide" EXACT RESID-name []
xref	DiffAvg: "436.33"
xref	DiffFormula: "C 0 Fe 4 H -6 N 0 Ni 1 O 0 S 5"
xref	DiffMono: "435.488498"
xref	Formula: "C 21 Fe 4 H 26 N 8 Ni 1 O 6 S 10"
xref	MassAvg: "1089.16"
xref	MassMono: "1087.593333"
xref	Origin: "C, C, C, C, C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00741 nickel containing modified residue ! nickel containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.316. MOD:00316 N4,N4-dimethyl-L-asparagine

Table 318. Term [MOD:00316]
id	MOD:00316
name	N4,N4-dimethyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4,N4-dimethyl-L-asparagine." [PubMed:12964758, PubMed:14570711, PubMed:8783012, RESID:AA0311, UniMod:36#N]
synonym	"(2S)-2-amino-4-(dimethylamino)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N4,N4-dimethylbutanediamic acid" EXACT RESID-alternate []
synonym	"beta-dimethylasparagine" RELATED RESID-misnomer []
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"MOD_RES N4,N4-dimethylasparagine" EXACT UniProt-feature []
synonym	"N(gamma),N(gamma)-dimethylasparagine" EXACT RESID-alternate []
synonym	"N4,N4-dimethyl-L-asparagine" EXACT RESID-name []
synonym	"N4,N4-dimethylated L-asparagine" EXACT PSI-MOD-alternate []
synonym	"N4Me2Asn" EXACT PSI-MOD-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 6 H 10 N 2 O 2"
xref	MassAvg: "142.16"
xref	MassMono: "142.074228"
xref	Origin: "N"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00429 dimethylated residue ! dimethylated residue
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00673 methylated asparagine ! methylated asparagine

2.317. MOD:00317 N6-3,4-didehydroretinylidene-L-lysine

Table 319. Term [MOD:00317]
id	MOD:00317
name	N6-3,4-didehydroretinylidene-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-3,4-didehydroretinylidene-L-lysine." [PubMed:10717661, PubMed:3257009, PubMed:4056688, RESID:AA0312, UniMod:433#K]
synonym	"(S)-2-amino-6-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)-2,4,6,8-nonatetraenylidene]aminohexanoic acid" EXACT RESID-systematic []
synonym	"3,4-didehydroretinylidene" RELATED UniMod-description []
synonym	"Didehydroretinylidene" RELATED PSI-MS-label []
synonym	"N6-(3,4-didehydroretinylidene)-L-lysine" EXACT RESID-name []
synonym	"N6-3-dehydroretinal-L-lysine" EXACT RESID-alternate []
synonym	"N6-3-dehydroretinyl-lysine" EXACT RESID-alternate []
xref	DiffAvg: "264.41"
xref	DiffFormula: "C 20 H 24 N 0 O 0"
xref	DiffMono: "264.187801"
xref	Formula: "C 26 H 36 N 2 O 1"
xref	MassAvg: "392.59"
xref	MassMono: "392.282764"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.318. MOD:00318 4'-(S-L-cysteinyl)-L-tryptophyl quinone

Table 320. Term [MOD:00318]
id	MOD:00318
name	4'-(S-L-cysteinyl)-L-tryptophyl quinone
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-tryptophan residue by a thioether bond to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone." [PubMed:11555656, PubMed:11717396, RESID:AA0313]
comment	Cross-link 2; secondary to RESID:AA0148.
synonym	"(2R)-2-amino-3-[(3-[(2S)-2-amino-2-carboxyethyl]-6,7-dioxo-6,7-dihydro-1H-indol-4-yl)sulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"3-(2-amino-2-carboxyethyl)-4-[2-amino-2-carboxyethyl]sulfanyl-6,7-indolinedione" EXACT RESID-alternate []
synonym	"4'-(L-cystein-S-yl)-L-tryptophyl quinone" EXACT RESID-name []
synonym	"4-(S-cysteinyl)tryptophan-6,7-dione" EXACT RESID-alternate []
synonym	"CROSSLNK 4'-cysteinyl-tryptophylquinone (Cys-Trp)" EXACT UniProt-feature []
synonym	"CTQ" EXACT RESID-alternate []
synonym	"cysteine tryptophylquinone" EXACT RESID-alternate []
xref	DiffAvg: "27.97"
xref	DiffFormula: "C 0 H -4 N 0 O 2 S 0"
xref	DiffMono: "27.958529"
xref	Formula: "C 14 H 11 N 3 O 4 S 1"
xref	MassAvg: "317.32"
xref	MassMono: "317.047027"
xref	Origin: "C, W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.319. MOD:00319 3-(S-L-cysteinyl)-L-aspartic acid

Table 321. Term [MOD:00319]
id	MOD:00319
name	3-(S-L-cysteinyl)-L-aspartic acid
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-aspartic acid residue by a thioether bond to form 2-(S-L-cysteinyl)-L-aspartic acid." [PubMed:11555656, PubMed:11717396, RESID:AA0314]
comment	Cross-link 2.
synonym	"(2R,3S)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanedioic acid" EXACT RESID-systematic []
synonym	"(2R,3S,6R)-2,6-diamino-3-carboxy-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"3-(L-cystein-S-yl)-L-aspartic acid" EXACT RESID-name []
synonym	"3-carboxy-L-lanthionine" EXACT RESID-alternate []
synonym	"CROSSLNK 3-cysteinyl-aspartic acid (Cys-Asp)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 7 H 8 N 2 O 4 S 1"
xref	MassAvg: "216.21"
xref	MassMono: "216.020478"
xref	Origin: "C, D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues

2.320. MOD:00320 4-(S-L-cysteinyl)-L-glutamic acid

Table 322. Term [MOD:00320]
id	MOD:00320
name	4-(S-L-cysteinyl)-L-glutamic acid
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-glutamic acid residue by a thioether bond to form 4-(S-L-cysteinyl)-L-glutamic acid." [ChEBI:20293, PubMed:11555656, PubMed:11717396, RESID:AA0315]
comment	Cross-link 2.
synonym	"(2S,3S,7R)-2,7-diamino-4-carboxy-5-thiaoctanedioic acid" EXACT RESID-alternate []
synonym	"(2S,4S)-2-amino-4-[®-2-amino-2-carboxyethyl]sulfanylpentanedioic acid" EXACT RESID-systematic []
synonym	"4-(L-cystein-S-yl)-L-glutamic acid" EXACT RESID-name []
synonym	"CROSSLNK 4-cysteinyl-glutamic acid (Cys-Glu)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 8 H 10 N 2 O 4 S 1"
xref	MassAvg: "230.24"
xref	MassMono: "230.036128"
xref	Origin: "C, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.321. MOD:00321 cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid L-aspartate ester

Table 323. Term [MOD:00321]
id	MOD:00321
name	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid L-aspartate ester
def	"A protein modification that effectively converts an L-aspartic acid residue to cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid L-aspartate ester." [PubMed:11435437, PubMed:7949339, RESID:AA0316, UniMod:434#D]
synonym	"(7Z,14Xi)-14-[(S)-3-amino-3-carboxy-propanoyl]oxy-10,13-dioxo-7-heptadecenoic acid" EXACT RESID-systematic []
synonym	"barley lipid transfer protein modification" EXACT RESID-alternate []
synonym	"CHDH" RELATED PSI-MS-label []
synonym	"cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid L-aspartate ester" EXACT RESID-name []
synonym	"cis-14-hydroxy-10,13-dioxo-7-heptadecenoic ester" RELATED UniMod-description []
synonym	"LIPID Cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester" EXACT UniProt-feature []
xref	DiffAvg: "294.39"
xref	DiffFormula: "C 17 H 26 N 0 O 4"
xref	DiffMono: "294.183109"
xref	Formula: "C 21 H 31 N 1 O 7"
xref	MassAvg: "409.48"
xref	MassMono: "409.210052"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.322. MOD:00322 1'-methyl-L-histidine

Table 324. Term [MOD:00322]
id	MOD:00322
name	1'-methyl-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to tele-methyl-L-histidine." [PubMed:10601317, PubMed:11474090, PubMed:11875433, PubMed:6692818, PubMed:8076, PubMed:8645219, RESID:AA0317]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-methyl-L-histidine" EXACT RESID-name []
synonym	"3-methylhistidine" RELATED RESID-misnomer []
synonym	"4-methyl-histidine" RELATED RESID-misnomer []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Tele-methylhistidine" EXACT UniProt-feature []
synonym	"N(epsilon)-methylhistidine" EXACT RESID-alternate []
synonym	"N(tau)-methylhistidine" EXACT RESID-alternate []
synonym	"NteleMeHis" EXACT PSI-MOD-label []
synonym	"tele-methylated L-histidine" EXACT PSI-MOD-alternate []
synonym	"tele-methylhistidine" EXACT RESID-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 9 N 3 O 1"
xref	MassAvg: "151.17"
xref	MassMono: "151.074562"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00724 N-methylated L-histidine ! N-methylated L-histidine

2.323. MOD:00323 L-lysine methyl ester

Table 325. Term [MOD:00323]
id	MOD:00323
name	L-lysine methyl ester
def	"A protein modification that effectively converts an L-lysine residue to L-lysine methyl ester." [PubMed:10973948, PubMed:11875433, RESID:AA0318, UniMod:34#C-term]
subset	PSI-MOD-slim
synonym	"2,6-diaminohexanoic methyl ester" EXACT RESID-alternate []
synonym	"alpha,epsilon-diaminocaproic methyl ester" EXACT RESID-alternate []
synonym	"L-lysine methyl ester" EXACT RESID-name []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methyl (S)-2,6-diaminohexanoate" EXACT RESID-systematic []
synonym	"methyl esterified L-lysine" EXACT PSI-MOD-alternate []
synonym	"methyl L-lysinate" EXACT RESID-alternate []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES Lysine methyl ester" EXACT UniProt-feature []
synonym	"OMeLys" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 15 N 2 O 2"
xref	MassAvg: "159.21"
xref	MassMono: "159.113353"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01683 monomethylated L-lysine ! monomethylated L-lysine
is_a	MOD:01689 alpha-carboxyl methylated residue ! alpha-carboxyl methylated residue

2.324. MOD:00324 L-serinyl molybdenum bis(molybdopterin guanine dinucleotide)

Table 326. Term [MOD:00324]
id	MOD:00324
name	L-serinyl molybdenum bis(molybdopterin guanine dinucleotide)
def	"A protein modification that effectively converts an L-serine residue to L-serinyl molybdenum bis(molybdopterin guanine dinucleotide)." [PubMed:8658132, PubMed:8658134, RESID:AA0319]
synonym	"2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotide" EXACT RESID-alternate []
synonym	"bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-O3-serinyl-molybdenum oxide" EXACT RESID-systematic []
synonym	"L-serinyl molybdenum bis(molybdopterin guanine dinucleotide)" EXACT RESID-name []
xref	DiffAvg: "1588.01"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 27 P 4 S 4"
xref	DiffMono: "1588.980690"
xref	Formula: "C 43 H 52 Mo 1 N 21 O 29 P 4 S 4"
xref	MassAvg: "1675.09"
xref	MassMono: "1676.012718"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.325. MOD:00325 L-beta-methylthioasparagine

Table 327. Term [MOD:00325]
id	MOD:00325
name	L-beta-methylthioasparagine
def	"A protein modification that effectively converts an L-asparagine residue to L-beta-methylthioasparagine." [RESID:AA0320, UniMod:39#N]
comment	This modification was predicted for ribosomal protein S12 in Bacillus subtilis when the sequence in the original version of the genome was reported to have asparagine rather than aspartic acid at the position of the methylthioaspartic acid modification (see MOD:00237). Two groups independently confirmed that the genome sequence was incorrect. The sequence in the revised genome has aspartic acid at that position. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2R,3Xi)-2-amino-3-(methylsulfanyl)-4-butanediamic acid" EXACT RESID-systematic []
synonym	"2,4-diamino-3-(methylsulfanyl)-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"3-(methylthio)-L-asparagine" EXACT RESID-name []
synonym	"3-carboxamido-S-methyl-cysteine" EXACT RESID-alternate []
synonym	"beta-(methylthio)asparagine" EXACT RESID-alternate []
synonym	"Beta-methylthiolation" RELATED UniMod-description []
synonym	"Methylthio" RELATED UniMod-interim []
xref	DiffAvg: "46.09"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 1"
xref	DiffMono: "45.987721"
xref	Formula: "C 5 H 8 N 2 O 2 S 1"
xref	MassAvg: "160.19"
xref	MassMono: "160.030649"
xref	Origin: "N"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01153 methylthiolated residue ! methylthiolated residue

2.326. MOD:00326 L-pyrrolysine (Lys)

Table 328. Term [MOD:00326]
id	MOD:00326
name	L-pyrrolysine (Lys)
def	"A protein modification that effectively converts an L-lysine residue to L-pyrrolysine (not known as a natural, post-translational modification process)." [PubMed:11435424, PubMed:12029131, PubMed:12029132, PubMed:15314242, PubMed:16096277, RESID:AA0321#LYS, UniMod:435#K]
comment	This entry is for the artifactual formation of L-pyrrolysine from lysine. For encoded L-pyrrolysine, use MOD:01187 [JSG].
synonym	"(2S)-2-amino-6-[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-ylcarbonyl]aminohexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-ylcarbonyl]azanylhexanoic acid" EXACT RESID-alternate []
synonym	"L-pyrrolysine" EXACT RESID-name []
synonym	"monomethylamine methyltransferase cofactor lysine adduct" EXACT RESID-alternate []
synonym	"N6-(4-methyl-1,2-didehydropyrrolidine-5-carboxyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-(4-methyl-delta-1-pyrroline-5-carboxyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-([(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl)-L-lysine" EXACT RESID-alternate []
synonym	"NON_STD Pyrrolysine" EXACT UniProt-feature []
synonym	"Pyl(Lys)" EXACT PSI-MOD-label []
xref	DiffAvg: "109.13"
xref	DiffFormula: "C 6 H 7 N 1 O 1"
xref	DiffMono: "109.052764"
xref	Formula: "C 12 H 19 N 3 O 2"
xref	MassAvg: "237.30"
xref	MassMono: "237.147727"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01187 L-pyrrolysine residue ! L-pyrrolysine residue

2.327. MOD:00327 3-hydroxy-L-tryptophan

Table 329. Term [MOD:00327]
id	MOD:00327
name	3-hydroxy-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to a 3-hydroxy-L-tryptophan." [PubMed:10024453, PubMed:11457355, RESID:AA0322]
synonym	"(2S,3S)-2-amino-3-hydroxy-3-(1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"3-hydroxy-L-tryptophan" EXACT RESID-name []
synonym	"3-hydroxylated L-tryptophan" EXACT PSI-MOD-alternate []
synonym	"3-hydroxytryptophan" EXACT RESID-alternate []
synonym	"3HyTrp" EXACT PSI-MOD-label []
synonym	"beta-hydroxytryptophan" EXACT RESID-alternate []
synonym	"MOD_RES 3-hydroxytryptophan" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 11 H 10 N 2 O 2"
xref	MassAvg: "202.21"
xref	MassMono: "202.074228"
xref	Origin: "W"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01622 monohydroxylated tryptophan ! monohydroxylated tryptophan

2.328. MOD:00328 O4'-(phospho-3'-DNA)-L-tyrosine

Table 330. Term [MOD:00328]
id	MOD:00328
name	O4'-(phospho-3'-DNA)-L-tyrosine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and the 3'-end of DNA through a phosphodiester bond to form O4'-(phospho-3'-DNA)-L-tyrosine." [PubMed:2211714, RESID:AA0323]
synonym	"(S)-2-amino-3-[4-(3'-deoxyribonucleic acid phosphonoxy)phenyl]propanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE O-(3'-phospho-DNA)-tyrosine intermediate" EXACT UniProt-feature []
synonym	"O4'-(phospho-3'-DNA)-L-tyrosine" EXACT RESID-name []
synonym	"O4'-L-tyrosine 3'-DNA phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 9 H 10 N 1 O 5 P 1"
xref	MassAvg: "243.15"
xref	MassMono: "243.029659"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.329. MOD:00329 hydroxyheme-L-glutamate ester

Table 331. Term [MOD:00329]
id	MOD:00329
name	hydroxyheme-L-glutamate ester
def	"A protein modification that effectively results from forming an adduct between a glutamic acid residue and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:11139583, PubMed:11821421, PubMed:11980497, RESID:AA0324, UniMod:436#E]
synonym	"5-hydroxymethyl protoporphyrin IX 5-glutamate ester" EXACT RESID-alternate []
synonym	"[3-[(S)-(4-amino-4-carboxy)butanoyloxymethyl]-7,12-diethenyl-8,13,17-trimethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"BINDING Heme (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"cytochrome P450 CYP4A family heme cofactor" EXACT RESID-alternate []
synonym	"Hydroxyheme" RELATED PSI-MS-label []
synonym	"hydroxyheme" RELATED UniMod-description []
synonym	"hydroxyheme-L-glutamate ester" EXACT RESID-name []
xref	DiffAvg: "614.48"
xref	DiffFormula: "C 34 Fe 1 H 30 N 4 O 4"
xref	DiffMono: "614.161643"
xref	Formula: "C 39 Fe 1 H 37 N 5 O 7"
xref	MassAvg: "743.60"
xref	MassMono: "743.204236"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.330. MOD:00330 (phospho-5'-guanosine)-L-histidine

Table 332. Term [MOD:00330]
id	MOD:00330
name	(phospho-5'-guanosine)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to a (phospho-5'-guanosine)-L-histidine." [PubMed:10529169, PubMed:10869342, PubMed:7559521, RESID:AA0325, UniMod:413#H]
synonym	"(2S)-2-amino-3-(1-(5'-adenosine phosphono)imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-(phospho-5'-guanosine)-L-histidine" EXACT RESID-name []
synonym	"ACT_SITE GMP-histidine intermediate" EXACT UniProt-feature []
synonym	"L-histidine 5'-guanosine phosphoramidester" EXACT RESID-alternate []
synonym	"L-histidine monoanhydride with 5'-guanylic acid" EXACT RESID-alternate []
synonym	"N(tau)-5'-guanylic-L-histidine" EXACT RESID-alternate []
synonym	"N1'-guanylylated histidine" EXACT RESID-alternate []
synonym	"phospho-guanosine" RELATED UniMod-description []
synonym	"Phosphoguanosine" RELATED PSI-MS-label []
synonym	"tele-5'-guanylic-L-histidine" EXACT RESID-alternate []
xref	DiffAvg: "345.21"
xref	DiffFormula: "C 10 H 12 N 5 O 7 P 1"
xref	DiffMono: "345.047434"
xref	Formula: "C 16 H 19 N 8 O 8 P 1"
xref	MassAvg: "482.35"
xref	MassMono: "482.106346"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01163 guanylated residue ! guanylated residue

2.331. MOD:00331 tetrakis-L-cysteinyl triiron tetrasulfide

Table 333. Term [MOD:00331]
id	MOD:00331
name	tetrakis-L-cysteinyl triiron tetrasulfide
def	"A protein modification that effectively converts four L-cysteine residues and a three-iron four-sulfur cluster to tetrakis-L-cysteinyl triiron tetrasulfide." [PubMed:11592901, PubMed:11941493, PubMed:2511202, PubMed:6094558, RESID:AA0326]
comment	Cross-link 4.
synonym	"bis[bis-L-cysteinyl iron disulfido]iron" EXACT RESID-alternate []
synonym	"di-mu-1:2kappaS-sulfido di-mu-2:3kappaS-sulfido iron bis(bis-S-cysteinyliron)" EXACT RESID-systematic []
synonym	"tetra-mu-sulfido tetrakis-S-L-cysteinyl triiron" EXACT RESID-alternate []
synonym	"tetrakis-L-cysteinyl linear [3Fe-4S] cluster" EXACT RESID-alternate []
synonym	"tetrakis-L-cysteinyl triiron tetrasulfide" EXACT RESID-name []
synonym	"tetrakis-L-cysteinyl triiron tetrasulfide D2 cluster" EXACT RESID-alternate []
xref	DiffAvg: "291.74"
xref	DiffFormula: "C 0 Fe 3 H -4 N 0 O 0 S 4"
xref	DiffMono: "291.663442"
xref	FormalCharge: "3-"
xref	Formula: "C 12 Fe 3 H 16 N 4 O 4 S 8"
xref	MassAvg: "704.30"
xref	MassMono: "703.700181"
xref	Origin: "C, C, C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.332. MOD:00332 omega-N-glucosyl-L-arginine

Table 334. Term [MOD:00332]
id	MOD:00332
name	omega-N-glucosyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N4-glucosyl-arginine." [PubMed:15279557, PubMed:8521968, PubMed:9536051, RESID:AA0327, UniMod:41#R]
synonym	"(2S)-2-amino-5-(beta-D-glucopyranosyl[imino(methylamino)methyl]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
synonym	"NG-beta-D-glucosylarginine" EXACT RESID-alternate []
synonym	"omega-N-(beta-D-glucosyl)-L-arginine" EXACT RESID-alternate []
synonym	"omega-N-glucosyl-L-arginine" EXACT RESID-name []
synonym	"omega-N-glycosyl-L-arginine" EXACT RESID-alternate []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 12 H 22 N 4 O 6"
xref	MassAvg: "318.33"
xref	MassMono: "318.153934"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00433 glucosylated residue ! glucosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:01980 omega-N-glycosyl-L-arginine ! omega-N-glycosyl-L-arginine

2.333. MOD:00333 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine

Table 335. Term [MOD:00333]
id	MOD:00333
name	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine
def	"A protein modification that effectively converts an L-asparagine residue to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine." [PubMed:7559516, PubMed:7835418, PubMed:8183363, RESID:AA0328, UniMod:437#C-term]
comment	UniMod origin shown as C-term [JSG].
synonym	"(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine" EXACT RESID-name []
synonym	"(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5-adenosine" RELATED UniMod-description []
synonym	"5'-O-[(3-aminopropoxy)(L-aspart-1-ylamino)phosphoryl]adenosine" EXACT RESID-systematic []
synonym	"9-(5'-O-[(3-aminopropoxy)(L-aspart-1-ylamino)phosphoryl]-beta-D-ribofuranosyl)adenine" EXACT RESID-alternate []
synonym	"C-Asn-deriv" RELATED UniMod-interim []
synonym	"microcin C7 asparagine modification" EXACT RESID-alternate []
synonym	"MOD_RES Aspartic acid 1-[(3-aminopropyl)(5'-adenosyl)phosphono]amide" EXACT UniProt-feature []
synonym	"N-(aspart-1-yl)-O-(3-aminopropyl)-O-(5'-adenosyl)phosphoramide" EXACT RESID-alternate []
xref	DiffAvg: "386.30"
xref	DiffFormula: "C 13 H 19 N 6 O 6 P 1"
xref	DiffMono: "386.110369"
xref	Formula: "C 17 H 26 N 8 O 9 P 1"
xref	MassAvg: "517.42"
xref	MassMono: "517.156036"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.334. MOD:00334 1'-heme-L-histidine

Table 336. Term [MOD:00334]
id	MOD:00334
name	1'-heme-L-histidine
def	"A protein modification that effectively results from forming an adduct between the tele nitrogen of a histidine residue and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron." [PubMed:12033922, PubMed:12121092, RESID:AA0329, UniMod:390#H]
synonym	"(S)-[7-ethenyl-12-[1-((2-amino-2-carboxyethyl)-1H-imidazol-1-yl)ethyl]-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate" EXACT RESID-systematic []
synonym	"1'-heme-L-histidine" EXACT RESID-name []
synonym	"2-[1-(N1'-histidyl)ethyl]protoporphyrin IX" EXACT RESID-alternate []
synonym	"BINDING Heme (covalent; via tele nitrogen)" EXACT UniProt-feature []
synonym	"Heme" RELATED PSI-MS-label []
synonym	"heme" RELATED UniMod-description []
synonym	"N(epsilon)-histidyl heme" EXACT RESID-alternate []
synonym	"N(tau)-histidyl heme" EXACT RESID-alternate []
synonym	"N1'-histidyl heme" EXACT RESID-alternate []
synonym	"tele-histidyl heme" EXACT RESID-alternate []
xref	DiffAvg: "616.50"
xref	DiffFormula: "C 34 Fe 1 H 32 N 4 O 4"
xref	DiffMono: "616.177293"
xref	Formula: "C 40 Fe 1 H 39 N 7 O 5"
xref	MassAvg: "753.64"
xref	MassMono: "753.236205"
xref	Origin: "H"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00699 porphyrin modified residue ! porphyrin modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.335. MOD:00335 (2S,3S,2’R)-3-methyllanthionine sulfoxide

Table 337. Term [MOD:00335]
id	MOD:00335
name	(2S,3S,2’R)-3-methyllanthionine sulfoxide
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form (2S,3S,2’R)-3-methyllanthionine sulfoxide." [PubMed:7737178, PubMed:9219543, RESID:AA0330]
comment	Cross-link 2.
synonym	"(2S,3S,4Xi,6R)-2,6-diamino-3-methyl-4-oxo-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(2S,3S,SXi)-2-amino-3-([®-2-amino-2-carboxyethyl]sulfinyl)butanoic acid" EXACT RESID-systematic []
synonym	"3-methyl-L-lanthionine S-oxide" EXACT RESID-alternate []
synonym	"3-methyl-L-lanthionine sulfoxide" EXACT RESID-name []
synonym	"CROSSLNK Beta-methyllanthionine sulfoxide (Thr-Cys)" EXACT UniProt-feature []
synonym	"S-oxy-3-methyllanthionine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 7 H 10 N 2 O 3 S 1"
xref	MassAvg: "202.23"
xref	MassMono: "202.041213"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues
relationship	has_functional_parent MOD:01981 3-methyllanthionine ! 3-methyllanthionine

2.336. MOD:00336 tris-L-cysteinyl L-aspartato diiron disulfide

Table 338. Term [MOD:00336]
id	MOD:00336
name	tris-L-cysteinyl L-aspartato diiron disulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-aspartic acid residue and a two-iron two-sulfur cluster to tris-L-cysteinyl L-aspartato diiron disulfide." [PubMed:10968624, PubMed:1312028, PubMed:7947772, RESID:AA0331]
comment	Cross-link 4.
synonym	"di-mu-sulfido(bis-S-cysteinyliron)(S-cysteinyl-O4-aspartatoiron)" EXACT RESID-systematic []
synonym	"METAL Iron-sulfur (2Fe-2S)" EXACT UniProt-feature []
synonym	"tris-L-cysteinyl L-aspartato diiron disulfide" EXACT RESID-name []
xref	DiffAvg: "171.78"
xref	DiffFormula: "C 0 Fe 2 H -4 N 0 O 0 S 2"
xref	DiffMono: "171.783814"
xref	FormalCharge: "2-"
xref	Formula: "C 13 Fe 2 H 16 N 4 O 6 S 5"
xref	MassAvg: "596.28"
xref	MassMono: "595.838311"
xref	Origin: "C, C, C, D"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.337. MOD:00337 S-carbamoyl-L-cysteine

Table 339. Term [MOD:00337]
id	MOD:00337
name	S-carbamoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-carbamoyl-L-cysteine." [PubMed:12586941, PubMed:240389, RESID:AA0332, UniMod:5#C]
synonym	"®-2-amino-3-(carbamoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(aminocarbonyl)sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-(aminocarbonyl)thiopropanoic acid" EXACT RESID-alternate []
synonym	"alpha-amino-beta-carbamylthiopropionic acid" EXACT RESID-alternate []
synonym	"beta-carbamylthioalanine" EXACT RESID-alternate []
synonym	"MOD_RES S-carbamoylcysteine" EXACT UniProt-feature []
synonym	"S-(aminocarbonyl)cysteine" EXACT RESID-alternate []
synonym	"S-carbamoyl-L-cysteine" EXACT RESID-name []
synonym	"S-carbamoylcysteine" EXACT RESID-alternate []
synonym	"S-carbamylcysteine" EXACT RESID-alternate []
synonym	"S-cysteinyl carbamate ester" EXACT RESID-alternate []
synonym	"SCbmCys" EXACT PSI-MOD-label []
xref	DiffAvg: "43.02"
xref	DiffFormula: "C 1 H 1 N 1 O 1 S 0"
xref	DiffMono: "43.005814"
xref	Formula: "C 4 H 6 N 2 O 2 S 1"
xref	MassAvg: "146.16"
xref	MassMono: "146.014998"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00398 carbamoylated residue ! carbamoylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.338. MOD:00338 S-cyano-L-cysteine

Table 340. Term [MOD:00338]
id	MOD:00338
name	S-cyano-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-cyano-L-cysteine." [PubMed:12586941, PubMed:4808702, RESID:AA0333, UniMod:438#C]
synonym	"(2R)-2-amino-3-thiocyanatopropanoic acid" EXACT RESID-systematic []
synonym	"alpha-amino-beta-thiocyanatopropionic acid" EXACT RESID-alternate []
synonym	"beta-thiocyanatoalanine" EXACT RESID-alternate []
synonym	"Cyano" RELATED PSI-MS-label []
synonym	"cyano" RELATED UniMod-description []
synonym	"MOD_RES S-cyanocysteine" EXACT UniProt-feature []
synonym	"S-cyano-L-cysteine" EXACT RESID-name []
synonym	"S-cyanocysteine" EXACT RESID-alternate []
synonym	"serine thiocyanic acid ester" EXACT RESID-alternate []
xref	DiffAvg: "25.01"
xref	DiffFormula: "C 1 H -1 N 1 O 0 S 0"
xref	DiffMono: "24.995249"
xref	Formula: "C 4 H 4 N 2 O 1 S 1"
xref	MassAvg: "128.15"
xref	MassMono: "128.004434"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00893 residues isobaric at 128.0-128.1 ! residues isobaric at 128.0-128.1
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.339. MOD:00339 L-cysteinyl hydrogenase diiron subcluster

Table 341. Term [MOD:00339]
id	MOD:00339
name	L-cysteinyl hydrogenase diiron subcluster
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteinyl hydrogenase diiron subcluster." [PubMed:10694885, PubMed:9836629, RESID:AA0334, UniMod:439#C]
comment	incidental to RESID:AA0140.
synonym	"1,7-biscarbonyl-1-(cystein-S-yl)-8-oxo-4-aza-2lambda(3),6 lambda(3)-dithia-1,7-diferratricyclo[4.2.0.0(2,7)]octane-1,7-dicarbonitrile" EXACT RESID-alternate []
synonym	"Diironsubcluster" RELATED PSI-MS-label []
synonym	"hydrogenase diiron subcluster" RELATED UniMod-description []
synonym	"L-cysteinyl hydrogenase diiron subcluster" EXACT RESID-name []
synonym	"METAL Diiron subcluster" EXACT UniProt-feature []
synonym	"mu-carbonyl-dicarbonyl-1kappaC,2kappaC-dicyanido-1kappaC,2kappaC-cysteinato-1kS-1,2-azadimethanthiol-1kS,2kS'-diiron" EXACT RESID-systematic []
xref	DiffAvg: "342.87"
xref	DiffFormula: "C 5 Fe 2 H -1 N 2 O 5 S 2"
xref	DiffMono: "342.786913"
xref	Formula: "C 8 Fe 2 H 4 N 3 O 6 S 3"
xref	MassAvg: "446.01"
xref	MassMono: "445.796098"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00738 iron containing modified residue ! iron containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.340. MOD:00340 S-amidino-L-cysteine

Table 342. Term [MOD:00340]
id	MOD:00340
name	S-amidino-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-amidino-L-cysteine." [PubMed:9148748, RESID:AA0335, UniMod:440#C]
synonym	"(2R)-2-amino-3-(carbamimidoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-amidinosulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-amidinothiopropanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE Amidino-cysteine intermediate" EXACT UniProt-feature []
synonym	"alpha-amino-beta-amidinothiopropionic acid" EXACT RESID-alternate []
synonym	"Amidino" RELATED PSI-MS-label []
synonym	"amidino" RELATED UniMod-description []
synonym	"beta-(S-isothiourea)alanine" EXACT RESID-alternate []
synonym	"beta-amidinothioalanine" EXACT RESID-alternate []
synonym	"S-amidino-L-cysteine" EXACT RESID-name []
synonym	"S-amidinocysteine" EXACT RESID-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 1 H 2 N 2 O 0 S 0"
xref	DiffMono: "42.021798"
xref	Formula: "C 4 H 7 N 3 O 1 S 1"
xref	MassAvg: "145.18"
xref	MassMono: "145.030983"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.341. MOD:00341 N-methyl-L-isoleucine

Table 343. Term [MOD:00341]
id	MOD:00341
name	N-methyl-L-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to N-methyl-L-isoleucine." [PubMed:11875433, RESID:AA0336]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
synonym	"(2S,3S)-2-methylamino-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N-methylisoleucine" EXACT UniProt-feature []
synonym	"N-methyl-L-isoleucine" EXACT RESID-name []
synonym	"N-methylated L-isoleucine" EXACT PSI-MOD-alternate []
synonym	"N-methylisoleucine" EXACT RESID-alternate []
synonym	"NMe1Ile" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 13 N 1 O 1"
xref	MassAvg: "127.19"
xref	MassMono: "127.099714"
xref	Origin: "I"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00715 methylated isoleucine ! methylated isoleucine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.342. MOD:00342 N-methyl-L-leucine

Table 344. Term [MOD:00342]
id	MOD:00342
name	N-methyl-L-leucine
def	"A protein modification that effectively converts an L-leucine residue to N-methyl-L-leucine." [PubMed:11875433, RESID:AA0337]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
synonym	"(S)-2-methylamino-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-(methylamino)-4-methyl-valeric acid" EXACT RESID-alternate []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"MOD_RES N-methylleucine" EXACT UniProt-feature []
synonym	"N-methyl-L-leucine" EXACT RESID-name []
synonym	"N-methylated L-leucine" EXACT PSI-MOD-alternate []
synonym	"N-methylleucine" EXACT RESID-alternate []
synonym	"NMe1Leu" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 13 N 1 O 1"
xref	MassAvg: "127.19"
xref	MassMono: "127.099714"
xref	Origin: "L"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue
is_a	MOD:01808 N-methylated leucine ! N-methylated leucine

2.343. MOD:00343 N-methyl-L-tyrosine

Table 345. Term [MOD:00343]
id	MOD:00343
name	N-methyl-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to N-methyl-L-tyrosine." [DeltaMass:0, RESID:AA0338]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
synonym	"(2S)-3-(4-hydroxyphenyl)-2-(methylamino)propanoic acid" EXACT RESID-systematic []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"MOD_RES N-methyltyrosine" EXACT UniProt-feature []
synonym	"N-methyl Tyrosinyl" EXACT DeltaMass-label []
synonym	"N-methyl-L-tyrosine" EXACT RESID-name []
synonym	"N-methylated L-tyrosine" EXACT PSI-MOD-alternate []
synonym	"N-methyltyrosine" EXACT RESID-alternate []
synonym	"NMe1Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 10 H 11 N 1 O 2"
xref	MassAvg: "177.20"
xref	MassMono: "177.078979"
xref	Origin: "Y"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00718 methylated tyrosine ! methylated tyrosine
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.344. MOD:00344 N-palmitoylglycine

Table 346. Term [MOD:00344]
id	MOD:00344
name	N-palmitoylglycine
def	"A protein modification that effectively converts a glycine residue to N-palmitoylglycine." [PubMed:12574119, RESID:AA0339]
comment	incidental to RESID:AA0060
subset	PSI-MOD-slim
synonym	"(hexadecanamido)acetic acid" EXACT RESID-alternate []
synonym	"(hexadecanoylamino)acetic acid" EXACT RESID-alternate []
synonym	"(hexadecanoylamino)ethanoic acid" EXACT RESID-systematic []
synonym	"LIPID N-palmitoyl glycine" EXACT UniProt-feature []
synonym	"N-(1-oxohexadecyl)glycine" EXACT RESID-alternate []
synonym	"N-palmitoyl-glycine" EXACT RESID-name []
synonym	"N-palmitoylated glycine" EXACT PSI-MOD-alternate []
synonym	"NPamGly" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "C 18 H 34 N 1 O 2"
xref	MassAvg: "296.47"
xref	MassMono: "296.258954"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01685 alpha-amino palmitoylated residue ! alpha-amino palmitoylated residue

2.345. MOD:00345 2-(S-L-cysteinyl)-L-phenylalanine

Table 347. Term [MOD:00345]
id	MOD:00345
name	2-(S-L-cysteinyl)-L-phenylalanine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-phenylalanine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-phenylalanine." [PubMed:12696888, PubMed:3936839, RESID:AA0340]
comment	Cross-link 2.
synonym	"(2R)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"(2R,5R)-2,5-diamino-3-thia-2-phenylmethylhexanedioic acid" EXACT RESID-alternate []
synonym	"2-(L-cystein-S-yl)-L-phenylalanine" EXACT RESID-name []
synonym	"alpha-(L-cystein-S-yl)-L-phenylalanine" EXACT RESID-alternate []
synonym	"CROSSLNK 2-cysteinyl-L-phenylalanine (Cys-Phe)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 2 S 1"
xref	MassAvg: "248.30"
xref	MassMono: "248.061949"
xref	Origin: "C, F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.346. MOD:00346 2-(S-L-cysteinyl)-D-phenylalanine

Table 348. Term [MOD:00346]
id	MOD:00346
name	2-(S-L-cysteinyl)-D-phenylalanine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-phenylalanine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-phenylalanine." [PubMed:12696888, PubMed:3936839, RESID:AA0341]
comment	Cross-link 2.
synonym	"(2S)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"(2S,5R)-2,5-diamino-3-thia-2-phenylmethylhexanedioic acid" EXACT RESID-alternate []
synonym	"2-(L-cystein-S-yl)-D-phenylalanine" EXACT RESID-name []
synonym	"alpha-(L-cystein-S-yl)-D-phenylalanine" EXACT RESID-alternate []
synonym	"CROSSLNK 2-cysteinyl-D-phenylalanine (Cys-Phe)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 2 S 1"
xref	MassAvg: "248.30"
xref	MassMono: "248.061949"
xref	Origin: "C, F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.347. MOD:00347 2-(S-L-cysteinyl)-D-allo-threonine

Table 349. Term [MOD:00347]
id	MOD:00347
name	2-(S-L-cysteinyl)-D-allo-threonine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-allo-threonine." [PubMed:12696888, PubMed:3936839, RESID:AA0342]
comment	Cross-link 2.
synonym	"(2R,5S,6R)-2,5-diamino-5-carboxy-6-hydroxy-4-thiaheptanoic acid" EXACT RESID-alternate []
synonym	"(2S,3R)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"2-(L-cystein-S-yl)-D-allo-threonine" EXACT RESID-name []
synonym	"alpha-(L-cystein-S-yl)-D-allo-threonine" EXACT RESID-alternate []
synonym	"CROSSLNK 2-cysteinyl-D-allo-threonine (Cys-Thr)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 7 H 10 N 2 O 3 S 1"
xref	MassAvg: "202.23"
xref	MassMono: "202.041213"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.348. MOD:00348 N-carbamoyl-L-alanine

Table 350. Term [MOD:00348]
id	MOD:00348
name	N-carbamoyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N-carbamoyl-L-alanine." [PubMed:12203680, RESID:AA0343]
synonym	"(S)-2-(carbamoylamino)propanoic acid" EXACT RESID-systematic []
synonym	"2-ureidopropanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N-carbamoylalanine" EXACT UniProt-feature []
synonym	"N-carbamoyl-L-alanine" EXACT RESID-name []
synonym	"N-carbamylalanine" EXACT RESID-alternate []
synonym	"N2CbmAla" EXACT PSI-MOD-label []
xref	DiffAvg: "43.02"
xref	DiffFormula: "C 1 H 1 N 1 O 1"
xref	DiffMono: "43.005814"
xref	Formula: "C 4 H 7 N 2 O 2"
xref	MassAvg: "115.11"
xref	MassMono: "115.050752"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01679 alpha-aminocarbamoylated residue ! alpha-aminocarbamoylated residue

2.349. MOD:00349 4-amino-3-isothiazolidinone-L-serine

Table 351. Term [MOD:00349]
id	MOD:00349
name	4-amino-3-isothiazolidinone-L-serine
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-serine residue to form 4-amino-3-isothiazolidinone-L-serine." [PubMed:12802338, PubMed:12802339, RESID:AA0344]
comment	Cross-link 2.
synonym	"(2S)-2-[(4R)-4-amino-3-oxo-1,2-thiazolidin-2-yl]-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-(4-amino-3-oxo-isothiazolidin-2-yl)-3-hydroxy-propanoic acid" EXACT RESID-alternate []
synonym	"4-amino-3-isothiazolidinone-L-serine" EXACT RESID-alternate []
synonym	"CROSSLNK N,N-(cysteine-1,S-diyl)serine (Cys-Ser)" EXACT UniProt-feature []
synonym	"N,N-(L-cysteine-1,S-diyl)-L-serine" EXACT RESID-name []
synonym	"serine-cysteine sulfenyl amide cross-link" EXACT RESID-alternate []
synonym	"serine-cysteine sulphenyl amide cross-link" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 3 S 1"
xref	MassAvg: "188.20"
xref	MassMono: "188.025563"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01861 isothiazolidinone ring crosslinked residues ! isothiazolidinone ring crosslinked residues

2.350. MOD:00350 L-threonyl-pentaglycyl-murein peptidoglycan

Table 352. Term [MOD:00350]
id	MOD:00350
name	L-threonyl-pentaglycyl-murein peptidoglycan
def	"A protein modification that effectively attaches an L-threonine residue to murein peptidoglycan by a pentaglycine linker peptide." [PubMed:10754567, PubMed:1638631, RESID:AA0345]
synonym	"(2R,6S)-2-(N-mureinyl-®-alanyl-(S)-isoglutamyl)amino-6-(threonyl-pentaglycyl)amino-pimeloyl-(S)-alanyl-(S)-alanine" EXACT RESID-alternate []
synonym	"L-threonyl-pentaglycyl-murein peptidoglycan" EXACT RESID-name []
synonym	"MOD_RES Pentaglycyl murein peptidoglycan amidated threonine" EXACT UniProt-feature []
xref	DiffAvg: "268.25"
xref	DiffFormula: "C 10 H 14 N 5 O 4"
xref	DiffMono: "268.104579"
xref	Formula: "C 14 H 22 N 6 O 7"
xref	MassAvg: "386.37"
xref	MassMono: "386.154997"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01159 peptidoglycanated residue ! peptidoglycanated residue

2.351. MOD:00351 N-glycyl-1-(phosphatidyl)ethanolamine

Table 353. Term [MOD:00351]
id	MOD:00351
name	N-glycyl-1-(phosphatidyl)ethanolamine
def	"A protein modification that effectively converts a glycine residue to N-glycyl-1-(phosphatidyl)ethanolamine." [PubMed:11100732, RESID:AA0346]
synonym	"®-1-hexadecanoyloxy-2-((Z)-9-octadecenoyloxy)-3-[2-(aminoacetylamino)ethyloxyphospho]propane" EXACT RESID-systematic []
synonym	"LIPID Phosphatidylethanolamine amidated glycine" EXACT UniProt-feature []
synonym	"N-glycyl-1-(phosphatidyl)ethanolamine" EXACT RESID-name []
synonym	"N-glycyl-1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine" EXACT RESID-alternate []
xref	DiffAvg: "699.99"
xref	DiffFormula: "C 39 H 74 N 1 O 7 P 1"
xref	DiffMono: "699.520290"
xref	Formula: "C 41 H 78 N 2 O 9 P 1"
xref	MassAvg: "774.05"
xref	MassMono: "773.544494"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.352. MOD:00352 L-glutamyl 5-omega-hydroxyceramide ester

Table 354. Term [MOD:00352]
id	MOD:00352
name	L-glutamyl 5-omega-hydroxyceramide ester
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl 5-omega-hydroxyceramide ester." [PubMed:10411887, PubMed:9651377, RESID:AA0347]
synonym	"(S)-2-amino-5-[30-((2S,3R,4E)-1,3-dihydroxyicos-4-en-2-ylamino)-30-oxotriacontan-1-yloxy]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"2-[30-(isoglutamyloxy)triacontanoyl]icosasphingosine" EXACT RESID-alternate []
synonym	"L-glutamyl 5-omega-hydroxyceramide ester" EXACT RESID-name []
synonym	"LIPID Omega-hydroxyceramide glutamate ester" EXACT UniProt-feature []
xref	DiffAvg: "761.31"
xref	DiffFormula: "C 50 H 96 N 0 O 4"
xref	DiffMono: "760.730862"
xref	Formula: "C 55 H 104 N 2 O 6"
xref	MassAvg: "889.44"
xref	MassMono: "888.789439"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.353. MOD:00353 S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium

Table 355. Term [MOD:00353]
id	MOD:00353
name	S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium
def	"A protein modification that effectively cross-links an L-tryptophan residue with an L-tyrosine residue by a carbon-carbon bond, and cross-links the L-tyrosine residue to an L-methionine residue by a thioether bond to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium." [PubMed:12172540, PubMed:16285713, RESID:AA0348]
comment	Cross-link 3.
synonym	"5'-(6'-tryptophyl)-tyrosin-3'-yl-methionin-S-ium" EXACT RESID-alternate []
synonym	"S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium" EXACT RESID-name []
xref	DiffAvg: "-3.02"
xref	DiffFormula: "C 0 H -3 N 0 O 0 S 0"
xref	DiffMono: "-3.024024"
xref	FormalCharge: "1+"
xref	Formula: "C 25 H 25 N 4 O 4 S 1"
xref	MassAvg: "477.56"
xref	MassMono: "477.159103"
xref	Origin: "M, W, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.354. MOD:00354 O-(riboflavin phosphoryl)-L-threonine

Table 356. Term [MOD:00354]
id	MOD:00354
name	O-(riboflavin phosphoryl)-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-(riboflavin phosphoryl)-L-threonine." [PubMed:10587447, PubMed:11163785, PubMed:11248234, RESID:AA0349, UniMod:442#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(riboflavin 5'-hydrogen phosphonoxy)butanoic acid" EXACT RESID-systematic []
synonym	"FMN" RELATED PSI-MS-label []
synonym	"MOD_RES FMN phosphoryl threonine" EXACT UniProt-feature []
synonym	"O-(riboflavin phosphoryl)-L-threonine" EXACT RESID-name []
synonym	"O3-(riboflavin phosphoryl)" RELATED UniMod-description []
synonym	"O3-threonyl flavin mononucleotide" EXACT RESID-alternate []
synonym	"O3-threonyl FMN" EXACT RESID-alternate []
synonym	"OFMNThr" EXACT PSI-MOD-label []
xref	DiffAvg: "438.33"
xref	DiffFormula: "C 17 H 19 N 4 O 8 P 1"
xref	DiffMono: "438.094050"
xref	Formula: "C 21 H 26 N 5 O 10 P 1"
xref	MassAvg: "539.44"
xref	MassMono: "539.141729"
xref	Origin: "T"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01164 riboflavin-phosphoryl ! riboflavin-phosphoryl

2.355. MOD:00355 O-(riboflavin phosphoryl)-L-serine

Table 357. Term [MOD:00355]
id	MOD:00355
name	O-(riboflavin phosphoryl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(riboflavin phosphoryl)-L-serine." [RESID:AA0350, UniMod:442#S]
subset	PSI-MOD-slim
synonym	"®-2-amino-3-(riboflavin 5'-hydrogen phosphonoxy)propanoic acid" EXACT RESID-systematic []
synonym	"FMN" RELATED PSI-MS-label []
synonym	"MOD_RES FMN phosphoryl serine" EXACT UniProt-feature []
synonym	"O-(riboflavin phosphoryl)-L-serine" EXACT RESID-name []
synonym	"O3-(riboflavin phosphoryl)" RELATED UniMod-description []
synonym	"O3-seryl flavin mononucleotide" EXACT RESID-alternate []
synonym	"O3-seryl FMN" EXACT RESID-alternate []
synonym	"OFMNSer" EXACT PSI-MOD-label []
xref	DiffAvg: "438.33"
xref	DiffFormula: "C 17 H 19 N 4 O 8 P 1"
xref	DiffMono: "438.094050"
xref	Formula: "C 20 H 24 N 5 O 10 P 1"
xref	MassAvg: "525.41"
xref	MassMono: "525.126079"
xref	Origin: "S"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01164 riboflavin-phosphoryl ! riboflavin-phosphoryl

2.356. MOD:00356 S-(4a-FMN)-L-cysteine

Table 358. Term [MOD:00356]
id	MOD:00356
name	S-(4a-FMN)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(4a-FMN)-L-cysteine." [PubMed:12668455, PubMed:12846567, PubMed:7692961, RESID:AA0351, UniMod:443#C]
subset	PSI-MOD-slim
synonym	"®-2-amino-3-(4a-riboflavin 5'-dihydrogen phosphate)sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"4a-(S-cysteinyl)flavin mononucleotide" EXACT RESID-alternate []
synonym	"4a-(S-cysteinyl)FMN" EXACT RESID-alternate []
synonym	"FMNC" RELATED PSI-MS-label []
synonym	"MOD_RES S-4a-FMN cysteine" EXACT UniProt-feature []
synonym	"S-(4a-FMN)" RELATED UniMod-description []
synonym	"S-(4a-FMN)-L-cysteine" EXACT RESID-name []
synonym	"S4aFMNCys" EXACT PSI-MOD-label []
xref	DiffAvg: "456.35"
xref	DiffFormula: "C 17 H 21 N 4 O 9 P 1 S 0"
xref	DiffMono: "456.104615"
xref	Formula: "C 20 H 26 N 5 O 10 P 1 S 1"
xref	MassAvg: "559.49"
xref	MassMono: "559.113800"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.357. MOD:00357 1'-(8alpha-FMN)-L-histidine

Table 359. Term [MOD:00357]
id	MOD:00357
name	1'-(8alpha-FMN)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 1'-(8alpha-FMN)-L-histidine." [PubMed:11902668, PubMed:8611516, RESID:AA0352, UniMod:409#H]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(1-[8alpha riboflavin 5'-dihydrogen phosphate]imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"1'-(8alpha-FMN)-L-histidine" EXACT RESID-name []
synonym	"8alpha-(N(epsilon)-histidyl)FMN" EXACT RESID-alternate []
synonym	"8alpha-(N1'-histidyl)FMN" EXACT RESID-alternate []
synonym	"flavin mononucleotide" RELATED UniMod-description []
synonym	"FMNH" RELATED PSI-MS-label []
synonym	"MOD_RES Tele-8alpha-FMN histidine" EXACT UniProt-feature []
synonym	"N(tau)-(8alpha-FMN)-histidine" EXACT RESID-alternate []
synonym	"Ntele8aFMNHis" EXACT PSI-MOD-label []
synonym	"tele-(8alpha-FMN)-histidine" EXACT RESID-alternate []
xref	DiffAvg: "454.33"
xref	DiffFormula: "C 17 H 19 N 4 O 9 P 1"
xref	DiffMono: "454.088965"
xref	Formula: "C 23 H 26 N 7 O 10 P 1"
xref	MassAvg: "591.47"
xref	MassMono: "591.147877"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.358. MOD:00358 3'-(8alpha-FMN)-L-histidine

Table 360. Term [MOD:00358]
id	MOD:00358
name	3'-(8alpha-FMN)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 3'-(8alpha-FMN)-L-histidine." [PubMed:12417325, RESID:AA0353, UniMod:409#H]
comment	In a later publication, PubMed:19438211, the authors changed the enzyme activity, the connection from a histidine nitrogen to a cysteine sulfur, and the identity of the flavin from FMN to FAD. They now believe the modification is S-(8alpha-FAD)-L-cysteine, see MOD:00152. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(3-[8alpha riboflavin 5'-dihydrogen phosphate]imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"3'-(8alpha-FMN)-L-histidine" EXACT RESID-name []
synonym	"8alpha-(N(delta)-histidyl)FMN" EXACT RESID-alternate []
synonym	"8alpha-(N3'-histidyl)FMN" EXACT RESID-alternate []
synonym	"flavin mononucleotide" RELATED UniMod-description []
synonym	"FMNH" RELATED PSI-MS-label []
synonym	"N(pi)-(8alpha-FMN)-histidine" EXACT RESID-alternate []
synonym	"Npros8aFMNHis" EXACT PSI-MOD-label []
synonym	"pros-(8alpha-FMN)-histidine" EXACT RESID-alternate []
xref	DiffAvg: "454.33"
xref	DiffFormula: "C 17 H 19 N 4 O 9 P 1"
xref	DiffMono: "454.088965"
xref	Formula: "C 23 H 26 N 7 O 10 P 1"
xref	MassAvg: "591.47"
xref	MassMono: "591.147877"
xref	Origin: "H"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.359. MOD:00359 N2-acetyl-L-arginine

Table 361. Term [MOD:00359]
id	MOD:00359
name	N2-acetyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N2-acetyl-L-arginine." [PubMed:12883043, PubMed:1894641, RESID:AA0354]
synonym	"(S)-2-acetamido-5-carbamimidamidopentanoic acid" EXACT RESID-systematic []
synonym	"2-acetamido-5-guanidinopentanoic acid" EXACT RESID-alternate []
synonym	"2-acetylamino-5-guanidinopentanoic acid" EXACT RESID-alternate []
synonym	"AcArg" EXACT PSI-MOD-label []
synonym	"acetylarginine" EXACT RESID-alternate []
synonym	"alpha-acetylamino-delta-guanidinovaleric acid" EXACT RESID-alternate []
synonym	"MOD_RES N2-acetylarginine" EXACT UniProt-feature []
synonym	"N(alpha)-acetylarginine" EXACT RESID-alternate []
synonym	"N2-acetyl-L-arginine" EXACT RESID-name []
synonym	"N2-acetylated L-arginine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 15 N 4 O 2"
xref	MassAvg: "199.23"
xref	MassMono: "199.119501"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.360. MOD:00360 L-cysteinyl copper sulfido molybdopterin cytosine dinuncleotide

Table 362. Term [MOD:00360]
id	MOD:00360
name	L-cysteinyl copper sulfido molybdopterin cytosine dinuncleotide
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteinyl copper sulfido molybdopterin cytosine dinuncleotide." [PubMed:12475995, RESID:AA0355, UniMod:444#C]
synonym	"[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with cytosine)methyl-6-oxo-3,4-dimercapto-pteridino[6,7-5,6]pyranoato-S3,S4]-cysteinyl-S-copper-mu-sulfido-molybdenum hydroxide oxide" EXACT RESID-systematic []
synonym	"copper sulfido molybdopterin cytosine dinuncleotide" RELATED UniMod-description []
synonym	"CuSMo" RELATED PSI-MS-label []
synonym	"cysteinyl copper mu-sulfido Mo-pterin cytosine dinucleotide" EXACT RESID-alternate []
synonym	"L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide" EXACT RESID-name []
xref	DiffAvg: "922.07"
xref	DiffFormula: "C 19 Cu 1 H 24 Mo 1 N 8 O 15 P 2 S 3"
xref	DiffMono: "922.834854"
xref	Formula: "C 22 Cu 1 H 29 Mo 1 N 9 O 16 P 2 S 4"
xref	MassAvg: "1025.20"
xref	MassMono: "1025.844039"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.361. MOD:00361 tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide

Table 363. Term [MOD:00361]
id	MOD:00361
name	tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an S-adenosylmethionine and a four-iron four-sulfur cluster to tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide." [PubMed:11222759, PubMed:14704425, RESID:AA0356]
comment	Cross-link 3.
synonym	"METAL Iron-sulfur (4Fe-4S-S-AdoMet)" EXACT UniProt-feature []
synonym	"tetra-mu3-sulfido(S-adenosylmethion-N,O-diyliron)tris(S-cysteinyliron)" EXACT RESID-systematic []
synonym	"tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide" EXACT RESID-name []
xref	DiffAvg: "747.03"
xref	DiffFormula: "C 15 Fe 4 H 19 N 6 O 5 S 5"
xref	DiffMono: "746.742346"
xref	FormalCharge: "1-"
xref	Formula: "C 24 Fe 4 H 34 N 9 O 8 S 8"
xref	MassAvg: "1056.45"
xref	MassMono: "1055.769901"
xref	Origin: "C, C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.362. MOD:00362 tris-L-cysteinyl L-arginyl diiron disulfide

Table 364. Term [MOD:00362]
id	MOD:00362
name	tris-L-cysteinyl L-arginyl diiron disulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-arginine residue and a two-iron two-sulfur cluster to tris-L-cysteinyl L-arginyl diiron disulfide." [PubMed:14704425, RESID:AA0357]
comment	Cross-link 4.
synonym	"di-mu-sulfido(N(eta1)-arginyl-S-cysteinyliron)(bis-S-cysteinyliron)" EXACT RESID-systematic []
synonym	"METAL Iron-sulfur (2Fe-2S)" EXACT UniProt-feature []
synonym	"tris-L-cysteinyl L-arginyl diiron disulfide" EXACT RESID-name []
xref	DiffAvg: "172.79"
xref	DiffFormula: "C 0 Fe 2 H -3 N 0 O 0 S 2"
xref	DiffMono: "172.791639"
xref	FormalCharge: "2-"
xref	Formula: "C 15 Fe 2 H 24 N 7 O 4 S 5"
xref	MassAvg: "638.39"
xref	MassMono: "637.920304"
xref	Origin: "C, C, C, R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.363. MOD:00363 L-cysteinyl-L-selenocysteine (Cys-Sec)

Table 365. Term [MOD:00363]
id	MOD:00363
name	L-cysteinyl-L-selenocysteine (Cys-Sec)
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-selenocysteine residues to form L-cysteinyl-L-selenocystine." [PubMed:12911312, RESID:AA0358#SEC]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(R,R)-2-amino-3-[3-(2-aminopropanoic acid)sulfanyl]selanylpropanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Cysteinyl-selenocysteine (Cys-Sec)" EXACT UniProt-feature []
synonym	"CROSSLNK Cysteinyl-selenocysteine (Sec-Cys)" EXACT UniProt-feature []
synonym	"L-cysteinyl-L-selenocysteine" EXACT RESID-name []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0 Se 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 2 S 1 Se 1"
xref	MassAvg: "251.17"
xref	MassMono: "251.947170"
xref	Origin: "C, U"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01158 modified L-selenocysteine residue ! modified L-selenocysteine residue
is_a	MOD:01627 L-cysteinyl-L-selenocysteine ! L-cysteinyl-L-selenocysteine

2.364. MOD:00364 5-hydroxy-N6,N6,N6-trimethyl-L-lysine

Table 366. Term [MOD:00364]
id	MOD:00364
name	5-hydroxy-N6,N6,N6-trimethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 5-hydroxy-N6,N6,N6-trimethyl-L-lysine." [PubMed:11349130, PubMed:14661085, RESID:AA0359, UniMod:445#K]
comment	Incidental to RESID:AA0278; secondary to RESID:AA0028; secondary to RESID:AA0074.
synonym	"(2R,5Xi)-5-amino-5-carboxy-2-hydroxy-N,N,N-trimethylpentan-1-aminium" EXACT RESID-systematic []
synonym	"(2Xi,5S)-5-amino-5-carboxy-2-hydroxy-N,N,N-trimethylpentanaminium" EXACT RESID-alternate []
synonym	"(2Xi,5S)-5-azanyl-5-carboxy-2-hydroxy-N,N,N-trimethylpentanazanium" EXACT RESID-alternate []
synonym	"5-hydroxy-N(zeta)-trimethyllysine" EXACT RESID-alternate []
synonym	"5-hydroxy-N6,N6,N6-trimethyl" RELATED UniMod-description []
synonym	"5-hydroxy-N6,N6,N6-trimethyl-L-lysine" EXACT RESID-name []
synonym	"5-hydroxy-N6,N6,N6-trimethyllysin-N6-ium" EXACT RESID-alternate []
synonym	"5-hydroxy-N6,N6,N6-trimethyllysine cation" EXACT RESID-alternate []
synonym	"5-hydroxylated N6,N6,N6-trimethylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"5HyN6Me3Lys" EXACT PSI-MOD-label []
synonym	"alpha-amino-epsilon-dimethylamino-delta-hydroxycaproic acid" EXACT RESID-alternate []
synonym	"delta-hydroxy-epsilon-N,N,N-trimethyllysine" EXACT RESID-alternate []
synonym	"Hydroxytrimethyl" RELATED PSI-MS-label []
synonym	"lysine derivative Lys(z)" EXACT RESID-alternate []
synonym	"MOD_RES N6,N6,N6-trimethyl-5-hydroxylysine" EXACT UniProt-feature []
xref	DiffAvg: "59.09"
xref	DiffFormula: "C 3 H 7 N 0 O 1"
xref	DiffMono: "59.049141"
xref	FormalCharge: "1+"
xref	Formula: "C 9 H 19 N 2 O 2"
xref	MassAvg: "187.26"
xref	MassMono: "187.144104"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
relationship	has_functional_parent MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine
relationship	has_functional_parent MOD:00083 N6,N6,N6-trimethyl-L-lysine ! N6,N6,N6-trimethyl-L-lysine

2.365. MOD:00365 N-(L-isoglutamyl)-glycine

Table 367. Term [MOD:00365]
id	MOD:00365
name	N-(L-isoglutamyl)-glycine
def	"A protein modification that effectively crosslinks an L-glutamic acid residue and a glycine residue by an isopeptide bond to form N-(L-isoglutamyl)-glycine." [PubMed:14531691, RESID:AA0360]
comment	Cross-link 2.
synonym	"(S)-2-amino-5-(carboxymethyl)amino-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N5-(carboxymethyl)-pentanediamic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoglutamyl glycine isopeptide (Gly-Glu)" EXACT UniProt-feature []
synonym	"isoglutamyl glycine" EXACT RESID-alternate []
synonym	"N-(L-isoglutamyl)-glycine" EXACT RESID-name []
synonym	"N-gamma-glutamylglycine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 9 N 2 O 3"
xref	MassAvg: "169.16"
xref	MassMono: "169.061317"
xref	Origin: "E, G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.366. MOD:00366 O-sulfo-L-serine

Table 368. Term [MOD:00366]
id	MOD:00366
name	O-sulfo-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-sulfo-L-serine." [PubMed:14752058, RESID:AA0361, UniMod:40#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(sulfooxy)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-hydroxypropanoic acid 3-sulfate" EXACT RESID-alternate []
synonym	"MOD_RES Sulfoserine" EXACT UniProt-feature []
synonym	"O-sulfo-L-serine" EXACT RESID-name []
synonym	"O-Sulfonation" RELATED UniMod-description []
synonym	"O3-sulfonoserine" EXACT RESID-alternate []
synonym	"O3-sulfoserine" EXACT RESID-alternate []
synonym	"serine sulfate ester" EXACT RESID-alternate []
synonym	"Sulfo" RELATED PSI-MS-label []
xref	DiffAvg: "80.06"
xref	DiffFormula: "C 0 H 0 N 0 O 3 S 1"
xref	DiffMono: "79.956815"
xref	Formula: "C 3 H 5 N 1 O 5 S 1"
xref	MassAvg: "167.13"
xref	MassMono: "166.988843"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00695 sulfated residue ! sulfated residue
is_a	MOD:00771 residues isobaric at 166.98-167.00 Da ! residues isobaric at 166.98-167.00 Da
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.367. MOD:00367 O-sulfo-L-threonine

Table 369. Term [MOD:00367]
id	MOD:00367
name	O-sulfo-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-sulfo-L-threonine." [PubMed:14752058, RESID:AA0362, UniMod:40#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(sulfooxy)butanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-hydroxybutanoic acid 3-sulfate" EXACT RESID-alternate []
synonym	"MOD_RES Sulfothreonine" EXACT UniProt-feature []
synonym	"O-sulfo-L-threonine" EXACT RESID-name []
synonym	"O-Sulfonation" RELATED UniMod-description []
synonym	"O3-sulfonothreonine" EXACT RESID-alternate []
synonym	"O3-sulfothreonine" EXACT RESID-alternate []
synonym	"Sulfo" RELATED PSI-MS-label []
synonym	"threonine sulfate ester" EXACT RESID-alternate []
xref	DiffAvg: "80.06"
xref	DiffFormula: "C 0 H 0 N 0 O 3 S 1"
xref	DiffMono: "79.956815"
xref	Formula: "C 4 H 7 N 1 O 5 S 1"
xref	MassAvg: "181.16"
xref	MassMono: "181.004493"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00695 sulfated residue ! sulfated residue
is_a	MOD:00773 residues isobaric at 181.00-181.02 Da ! residues isobaric at 181.00-181.02 Da
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.368. MOD:00368 N-carboxy-L-methionine

Table 370. Term [MOD:00368]
id	MOD:00368
name	N-carboxy-L-methionine
def	"A protein modification that effectively converts an L-methionine residue to N-carboxy-L-methionine." [PubMed:10368287, PubMed:11120890, PubMed:12595263, PubMed:8312270, RESID:AA0363, UniMod:299#M]
comment	At least three protein crystallographic structures have been reported with this modification. However, no chemical evidence for this modification is provided, there were no reports of this modification before these crystallographic reports, and there is no metabolic explanation for the conversion of a formyl group to a carboxy group. There is confusion in its description, and misnaming is common. This modification is probably a misidentification of N-(dihydroxymethyl)methionine, the hydrated form of N-formylmethionine. See MOD:01446 [JSG].
synonym	"(S)-2-carboxyamino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-carbamic-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"2-carbamic-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxylation" RELATED UniMod-description []
synonym	"N-carboxy-L-methionine" EXACT RESID-name []
synonym	"N-carboxymethionine" EXACT RESID-alternate []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2 S 0"
xref	DiffMono: "43.989829"
xref	Formula: "C 6 H 10 N 1 O 3 S 1"
xref	MassAvg: "176.21"
xref	MassMono: "176.038139"
xref	Origin: "M"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.369. MOD:00369 O-acetyl-L-serine

Table 371. Term [MOD:00369]
id	MOD:00369
name	O-acetyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-acetyl-L-serine." [ChEBI:17981, PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, PubMed:16731519, PubMed:489587, PubMed:7309355, RESID:AA0364, UniMod:1#S]
comment	incidental to RESID:AA0051
subset	PSI-MOD-slim
synonym	"(2S)-3-(acetyloxy)-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"MOD_RES O-acetylserine" EXACT UniProt-feature []
synonym	"O-acetyl-L-serine" EXACT RESID-name []
synonym	"O-acetylated L-serine" EXACT PSI-MOD-alternate []
synonym	"O-acetylserine" EXACT RESID-alternate []
synonym	"OAcSer" EXACT PSI-MOD-label []
synonym	"serine acetate ester" EXACT RESID-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00644 O-acetylated residue ! O-acetylated residue
is_a	MOD:00647 acetylated L-serine ! acetylated L-serine

2.370. MOD:00370 (E)-2,3-didehydrotyrosine

Table 372. Term [MOD:00370]
id	MOD:00370
name	(E)-2,3-didehydrotyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to (E)-2,3-didehydrotyrosine." [PubMed:12623015, RESID:AA0365]
comment	incidental to RESID:AA0184; incidental to RESID:AA0187; incidental to RESID:AA0188; incidental to RESID:AA0189; incidental to RESID:AA0378; incidental to RESID:AA0379; incidental to RESID:AA0380; incidental to RESID:AA0381
subset	PSI-MOD-slim
synonym	"(2E)-2-amino-3-(4-hydroxyphenyl)prop-2-enoic acid" EXACT RESID-systematic []
synonym	"(E)-2,3-didehydrogenated tyrosine" EXACT PSI-MOD-alternate []
synonym	"(E)-2,3-didehydrotyrosine" EXACT RESID-name []
synonym	"2-amino-3-oxo-butanoic_acid" RELATED UniMod-description []
synonym	"amino-(para-hydroxybenzylidenyl)acetic acid" EXACT RESID-alternate []
synonym	"blue non-fluorescent pocilloporin chromophore" EXACT RESID-alternate []
synonym	"Didehydro" RELATED PSI-MS-label []
synonym	"E-dHTyr" EXACT PSI-MOD-label []
synonym	"MOD_RES (E)-2,3-didehydrotyrosine" EXACT UniProt-feature []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"trans-dehydrotyrosine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 9 H 7 N 1 O 2"
xref	MassAvg: "161.16"
xref	MassMono: "161.047678"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00706 dehydrogenated tyrosine ! dehydrogenated tyrosine

2.371. MOD:00371 bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide

Table 373. Term [MOD:00371]
id	MOD:00371
name	bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide
def	"A protein modification that effectively converts two L-aspartic acid residues, three L-glutamic acid residues, an L-histidine residue, and a one-calcium, four-iron, four-oxygen cluster to bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide." [PubMed:14764885, RESID:AA0366]
comment	Cross-link 6.
synonym	"4Mn-Ca-4O cluster" EXACT RESID-alternate []
synonym	"bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide" EXACT RESID-name []
synonym	"mu3-1:2:3kappaO-oxido-mu3-1:3:4kappaO-oxido-mu3-2:3:4kappaO-oxido-mu4-1:2:4:5kappaO-oxido-N1'-histidino-O5-glutamato 2-manganese-O5,O5-glutamato 3-manganese-O4-aspartato 4-manganese-O4-aspartato-O5-glutamato 5-manganese" EXACT RESID-systematic []
synonym	"photosystem II catalytic cluster" EXACT RESID-alternate []
xref	DiffAvg: "317.78"
xref	DiffFormula: "C 0 Ca 1 H -6 Mn 4 N 0 O 4"
xref	DiffMono: "317.647480"
xref	Formula: "C 29 Ca 1 H 32 Mn 4 N 8 O 20"
xref	MassAvg: "1072.44"
xref	MassMono: "1071.888057"
xref	Origin: "D, D, E, E, E, H"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00740 manganese containing modified residue ! manganese containing modified residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01482 calcium containing modified residue ! calcium containing modified residue

2.372. MOD:00372 3'-(3'-L-tyrosinyl)-L-tyrosine

Table 374. Term [MOD:00372]
id	MOD:00372
name	3'-(3'-L-tyrosinyl)-L-tyrosine
def	"A protein modification that effectively cross-links two L-tyrosine residues with a carbon-carbon bond to form 3'-(3'-L-tyrosinyl)-L-tyrosine." [DeltaMass:0, PubMed:14249161, PubMed:637884, PubMed:8702710, PubMed:8937563, RESID:AA0367]
comment	Cross-link 2; From DeltaMass: Average Mass: -2.
synonym	"(2S,2’S)-3,3'-(6,6'-dihydroxybiphenyl-3,3'-diyl)bis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"3'-(L-tyros-3'-yl)-L-tyrosine" EXACT RESID-name []
synonym	"3,3'-BiTyr (Crosslink)" EXACT DeltaMass-label []
synonym	"6,6'-dihydroxy-(1,1'-biphenyl)-3,3'-bis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"alpha,alpha'-diamino-6,6'-dihydroxy-(1,1'-biphenyl)-3,3'-dipropanoic acid" EXACT RESID-alternate []
synonym	"bityrosine" EXACT RESID-alternate []
synonym	"o,o-dityrosine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 18 H 16 N 2 O 4"
xref	MassAvg: "324.34"
xref	MassMono: "324.111007"
xref	Origin: "Y, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.373. MOD:00373 3'-(O4'-L-tyrosinyl)-L-tyrosine

Table 375. Term [MOD:00373]
id	MOD:00373
name	3'-(O4'-L-tyrosinyl)-L-tyrosine
def	"A protein modification that effectively cross-links L-tyrosine residues with an ether bond to form 3'-(O4'-L-tyrosinyl)-L-tyrosine." [DeltaMass:0, PubMed:12719529, PubMed:7115340, PubMed:8702710, RESID:AA0368]
comment	Cross-link 2; secondary to RESID:AA0146; From DeltaMass: Average Mass: -2.
synonym	"(2S)-2-amino-3-[3-(4-[(2S)-2-amino-2-carboxyethyl]phenoxy)-4-hydroxyphenyl]propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-[4-(5-[(2S)-2-amino-2-carboxyethyl]-2-hydroxyphenoxy)phenyl]propanoic acid" EXACT RESID-alternate []
synonym	"3'-(L-tyros-O4'-yl)-L-tyrosine" EXACT RESID-name []
synonym	"CROSSLNK Isodityrosine (Tyr-Tyr)" EXACT UniProt-feature []
synonym	"IsodiTyr (Crosslink)" EXACT DeltaMass-label []
synonym	"isodityrosine" EXACT RESID-alternate []
synonym	"O-(5-(2-amino-2-carboxyethyl)-2-hydroxyphenyl)-L-tyrosine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 18 H 16 N 2 O 4"
xref	MassAvg: "324.34"
xref	MassMono: "324.111007"
xref	Origin: "Y, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.374. MOD:00374 3,4-dihydroxy-L-arginine

Table 376. Term [MOD:00374]
id	MOD:00374
name	3,4-dihydroxy-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to 3,4-dihydroxy-L-arginine." [PubMed:10978343, PubMed:12686488, RESID:AA0369, UniMod:425#R]
synonym	"(2S,3Xi,4Xi)-2-amino-5-carbamimidamido-3,4-dihydroxypentanoic acid" EXACT RESID-systematic []
synonym	"2-amino-5-guanidino-3,4-dihydroxypentanoic acid" EXACT RESID-alternate []
synonym	"3,4-dihydroxy-L-arginine" EXACT RESID-name []
synonym	"3,4-dihydroxylated L-arginine" EXACT PSI-MOD-alternate []
synonym	"34Hy2Arg" EXACT PSI-MOD-label []
synonym	"beta,gamma-dihydroxyarginine" EXACT RESID-alternate []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"MOD_RES 3,4-dihydroxyarginine" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 12 N 4 O 3"
xref	MassAvg: "188.19"
xref	MassMono: "188.090940"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:00682 hydroxylated arginine ! hydroxylated arginine

2.375. MOD:00375 4,5-dihydroxy-L-lysine

Table 377. Term [MOD:00375]
id	MOD:00375
name	4,5-dihydroxy-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4,5-dihydroxy-L-lysine." [PubMed:10978343, PubMed:12686488, RESID:AA0370, UniMod:425#K]
synonym	"(2S,4Xi,5Xi)-2,6-diamino-4,5-dihydroxyhexanoic acid" EXACT RESID-systematic []
synonym	"4,5-dihydroxy-L-lysine" EXACT RESID-name []
synonym	"4,5-dihydroxylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"45Hy2Lys" EXACT PSI-MOD-label []
synonym	"alpha,epsilon-diamino-delta,gamma-dihydroxycaproic acid" EXACT RESID-alternate []
synonym	"delta,gamma-dihydroxylysine" EXACT RESID-alternate []
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"MOD_RES 4,5-dihydroxylysine" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 12 N 2 O 3"
xref	MassAvg: "160.17"
xref	MassMono: "160.084792"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:00681 hydroxylated lysine ! hydroxylated lysine

2.376. MOD:00376 1'-(phospho-5'-adenosine)-L-histidine

Table 378. Term [MOD:00376]
id	MOD:00376
name	1'-(phospho-5'-adenosine)-L-histidine
def	"A protein modification that effectively crosslinks an L-histidine residue and 5'-phosphoadenosine through a phosphoramide ester bond to form 1'-(phospho-5'-adenosine)-L-histidine." [PubMed:15182206, PubMed:9323207, RESID:AA0371, UniMod:405#H]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-[1-(5'-adenosine phosphono)imidazol-4-yl]propanoic acid" EXACT RESID-systematic []
synonym	"1'-(phospho-5'-adenosine)-L-histidine" EXACT RESID-name []
synonym	"ACT_SITE Tele-AMP-histidine intermediate" EXACT UniProt-feature []
synonym	"AMP binding site" RELATED UniMod-description []
synonym	"L-histidine 5'-adenosine phosphoramidester" EXACT RESID-alternate []
synonym	"L-histidine monoanhydride with 5'-adenylic acid" EXACT RESID-alternate []
synonym	"N(tau)-5'-adenylic-L-histidine" EXACT RESID-alternate []
synonym	"N1'-adenylylated histidine" EXACT RESID-alternate []
synonym	"Phosphoadenosine" RELATED PSI-MS-label []
synonym	"tele-5'-adenylic-L-histidine" EXACT RESID-alternate []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "C 16 H 19 N 8 O 7 P 1"
xref	MassAvg: "466.35"
xref	MassMono: "466.111432"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01165 adenylated residue ! adenylated residue

2.377. MOD:00377 1'-(phospho-5'-uridine)-L-histidine

Table 379. Term [MOD:00377]
id	MOD:00377
name	1'-(phospho-5'-uridine)-L-histidine
def	"A protein modification that effectively crosslinks an L-histidine residue and 5'-phosphouridine through a phosphoramide ester bond to form 1'-(phospho-5'-uridine)-L-histidine." [PubMed:11467524, PubMed:321007, PubMed:380639, PubMed:8794735, RESID:AA0372, UniMod:417#H]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-[1-(5'-uridine phosphono)imidazol-4-yl]propanoic acid" EXACT RESID-systematic []
synonym	"1'-(phospho-5'-uridine)-L-histidine" EXACT RESID-name []
synonym	"ACT_SITE Tele-UMP-histidine intermediate" EXACT UniProt-feature []
synonym	"L-histidine 5'-uridine phosphoramidester" EXACT RESID-alternate []
synonym	"L-histidine monoanhydride with 5'-uridylic acid" EXACT RESID-alternate []
synonym	"N(tau)-5'-uridylic-L-histidine" EXACT RESID-alternate []
synonym	"N1'-uridylylated histidine" EXACT RESID-alternate []
synonym	"PhosphoUridine" RELATED PSI-MS-label []
synonym	"tele-5'-uridylic-L-histidine" EXACT RESID-alternate []
synonym	"uridine phosphodiester" RELATED UniMod-description []
xref	DiffAvg: "306.17"
xref	DiffFormula: "C 9 H 11 N 2 O 8 P 1"
xref	DiffMono: "306.025302"
xref	Formula: "C 15 H 18 N 5 O 9 P 1"
xref	MassAvg: "443.31"
xref	MassMono: "443.084214"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01166 uridylated residue ! uridylated residue

2.378. MOD:00378 L-aspartyl semialdehyde

Table 380. Term [MOD:00378]
id	MOD:00378
name	L-aspartyl semialdehyde
def	"A protein modification that effectively converts an L-aspartic acid residue to L-aspartyl semialdehyde." [PubMed:1093385, PubMed:14235557, PubMed:15237995, RESID:AA0373, UniMod:447#D]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"aspartyl 4-semialdehyde" EXACT PSI-MOD-alternate []
synonym	"aspartyl aldehyde" EXACT PSI-MOD-alternate []
synonym	"Deoxy" RELATED PSI-MS-label []
synonym	"L-aminosuccinaldehydic acid" EXACT RESID-alternate []
synonym	"L-aminosuccinic acid semialdehyde" EXACT RESID-alternate []
synonym	"L-aspartate-beta-semialdehyde" EXACT RESID-alternate []
synonym	"L-aspartic beta-semialdehyde" EXACT RESID-alternate []
synonym	"L-aspartyl aldehyde" EXACT RESID-name []
synonym	"L-beta-formylalanine" EXACT RESID-alternate []
synonym	"MOD_RES Aspartyl aldehyde" EXACT UniProt-feature []
synonym	"reduction" RELATED UniMod-description []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "C 0 H 0 N 0 O -1"
xref	DiffMono: "-15.994915"
xref	Formula: "C 4 H 5 N 1 O 2"
xref	MassAvg: "99.09"
xref	MassMono: "99.032028"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01161 deoxygenated residue ! deoxygenated residue

2.379. MOD:00379 L-serine microcin E492 siderophore ester

Table 381. Term [MOD:00379]
id	MOD:00379
name	L-serine microcin E492 siderophore ester
def	"A protein modification that effectively converts an L-serine residue to L-serine microcin E492 siderophore ester." [PubMed:15102848, RESID:AA0374, UniMod:448#C-term]
comment	UniMod origin corrected [JSG].
synonym	"L-serine microcin E492 siderophore ester" EXACT RESID-name []
synonym	"Microcin" RELATED PSI-MS-label []
synonym	"microcin E492 siderophore ester from serine" RELATED UniMod-description []
synonym	"MOD_RES Serine microcin E492 siderophore ester" EXACT UniProt-feature []
synonym	"N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine" EXACT RESID-systematic []
xref	DiffAvg: "831.69"
xref	DiffFormula: "C 36 H 37 N 3 O 20"
xref	DiffMono: "831.197041"
xref	Formula: "C 39 H 43 N 4 O 23"
xref	MassAvg: "935.78"
xref	MassMono: "935.231809"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.380. MOD:00380 L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)

Table 382. Term [MOD:00380]
id	MOD:00380
name	L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)
def	"A protein modification that effectively converts an L-aspartic acid residue to L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)." [PubMed:12910261, PubMed:14725769, RESID:AA0375, UniMod:424#D]
synonym	"2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotide" EXACT RESID-alternate []
synonym	"bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-aspartyl-molybdenum" EXACT RESID-systematic []
synonym	"L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)" EXACT RESID-name []
synonym	"molybdenum bis(molybdopterin guanine dinucleotide)" RELATED UniMod-description []
synonym	"MolybdopterinGD" RELATED PSI-MS-label []
synonym	"nitrate reductase A aspartyl Mo-bisMGD cofactor" EXACT RESID-alternate []
synonym	"phosphoric acid 4-(2-amino-4-oxo-3,4,5,6,-tetrahydro-pteridin-6-yl)-2-hydroxy-3,4-dimercapto-but-3-en-yl ester guanylate ester" EXACT RESID-alternate []
xref	DiffAvg: "1572.02"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 26 P 4 S 4"
xref	DiffMono: "1572.985775"
xref	Formula: "C 44 H 52 Mo 1 N 21 O 29 P 4 S 4"
xref	MassAvg: "1687.10"
xref	MassMono: "1688.012718"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01167 molybdopterin guanine dinucleotide ! molybdopterin guanine dinucleotide

2.381. MOD:00381 L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) (Sec)

Table 383. Term [MOD:00381]
id	MOD:00381
name	L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) (Sec)
def	"A protein modification that effectively converts an L-selenocysteine residue to L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)." [PubMed:11372198, PubMed:12220497, RESID:AA0376#SEC]
xref	DiffAvg: "1691.97"
xref	DiffFormula: "C 40 H 47 N 20 O 26 P 4 S 5 Se 0 W 1"
xref	DiffMono: "1691.003369"
xref	Formula: "C 43 H 52 N 21 O 27 P 4 S 5 Se 1 W 1"
xref	MassAvg: "1842.02"
xref	MassMono: "1841.957004"
xref	Origin: "U"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00746 tungsten containing modified residue ! tungsten containing modified residue
is_a	MOD:00748 pterin modified residue ! pterin modified residue
is_a	MOD:01158 modified L-selenocysteine residue ! modified L-selenocysteine residue

2.382. MOD:00382 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one

Table 384. Term [MOD:00382]
id	MOD:00382
name	3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one
def	"A protein modification that effectively crosslinks an L-methionyl-L-tyrosine dipeptide to form 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one." [PubMed:10852900, PubMed:11259412, PubMed:15491166, RESID:AA0377]
comment	carboxamidine; cross-link 1. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"3-(2-methylsulfanyl)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one" EXACT RESID-systematic []
synonym	"3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-amino-3,6-didehydropyrazin-2-ol" EXACT RESID-alternate []
synonym	"3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one" EXACT RESID-name []
synonym	"GFP-like chromoprotein asFP595 chromophore" EXACT RESID-alternate []
synonym	"L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine" EXACT RESID-alternate []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 14 H 15 N 2 O 2 S 1"
xref	MassAvg: "275.35"
xref	MassMono: "275.085424"
xref	Origin: "M, Y"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.383. MOD:00383 2-imino-glutamic acid 5-imidazolinone glycine

Table 385. Term [MOD:00383]
id	MOD:00383
name	2-imino-glutamic acid 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-glutamic acid residue and a glycine residue to form 2-imino-glutamic acid 5-imidazolinone glycine." [PubMed:11682051, RESID:AA0378]
comment	Cross-link 2; carboxamidine; cross-link 1; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"2,N-didehydroglutamyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"2-(3-carboxy-1-iminopropyl)-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"2-imino-glutamic acid 5-imidazolinone glycine" EXACT RESID-name []
synonym	"2-imino-glutamyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"4-[1-(carboxymethyl)-5-oxo-4,5-dihydro-1H-imidazol-2-yl]-4-iminobutanoic acid" EXACT RESID-systematic []
synonym	"[2-(3-carboxy-1-iminopropyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 2-iminomethyl-5-imidazolinone (Glu-Gly)" EXACT UniProt-feature []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 6 N 2 O 3"
xref	MassAvg: "166.14"
xref	MassMono: "166.037842"
xref	Origin: "E, G"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.384. MOD:00384 2-imino-methionine 5-imidazolinone glycine

Table 386. Term [MOD:00384]
id	MOD:00384
name	2-imino-methionine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-methionine residue and a glycine residue to form 2-imino-methionine 5-imidazolinone glycine." [PubMed:10852900, PubMed:12185250, PubMed:12909624, PubMed:15542608, RESID:AA0379]
comment	Cross-link 2; carboxamidine; cross-link 1; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[1-imino-3-(methylsulfanyl)propyl]-5-oxo-4,5-dihydro-imidazol-1-yl)acetic acid" EXACT RESID-alternate []
synonym	"(2-[3-(methylsulfanyl)propanimidoyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2,N-didehydromethionyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"2-[1-imino-3-(methylsulfanyl)propyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"2-imino-methionine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"2-imino-methionyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"CROSSLNK 2-iminomethyl-5-imidazolinone (Met-Gly)" EXACT UniProt-feature []
synonym	"GFP-like chromoprotein asFP595 chromophore" EXACT RESID-alternate []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"red fluorescent protein eqFP611 chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 8 N 2 O 1 S 1"
xref	MassAvg: "168.21"
xref	MassMono: "168.035734"
xref	Origin: "G, M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.385. MOD:00385 L-asparagine 5-imidazolinone glycine

Table 387. Term [MOD:00385]
id	MOD:00385
name	L-asparagine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-asparagine residue and a glycine residue to form L-asparagine 5-imidazolinone glycine." [PubMed:10504696, RESID:AA0380]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[(1S)-1,3-diamino-3-oxopropyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2-[(S)-1,3-diamino-3-oxopropyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"[2-(1,3-diamino-3-oxopropyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid" EXACT RESID-alternate []
synonym	"asparaginyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"CROSSLNK 5-imidazolinone (Asn-Gly)" EXACT UniProt-feature []
synonym	"L-asparagine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"Zoanthus sp. fluorescent protein FP506 chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 7 N 3 O 2"
xref	MassAvg: "153.14"
xref	MassMono: "153.053826"
xref	Origin: "G, N"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.386. MOD:00386 L-lysine 5-imidazolinone glycine

Table 388. Term [MOD:00386]
id	MOD:00386
name	L-lysine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-lysine residue and a glycine residue to form L-lysine 5-imidazolinone glycine." [PubMed:10504696, RESID:AA0381]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"(2-[(1S)-1,5-diaminopentyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2-[(S)-1,5-diaminopentanyl]-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"[2-(1,5-diaminopentanyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid" EXACT RESID-alternate []
synonym	"Anemonia majano fluorescent protein FP486 chromophore" EXACT RESID-alternate []
synonym	"CROSSLNK 5-imidazolinone (Lys-Gly)" EXACT UniProt-feature []
synonym	"L-lysine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"lysyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 8 H 13 N 3 O 1"
xref	MassAvg: "167.21"
xref	MassMono: "167.105862"
xref	Origin: "G, K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.387. MOD:00387 2-tetrahydropyridinyl-5-imidazolinone glycine

Table 389. Term [MOD:00387]
id	MOD:00387
name	2-tetrahydropyridinyl-5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-lysine residue and a glycine residue to form 2-tetrahydropyridinyl-5-imidazolinone glycine." [PubMed:10504696, PubMed:15628861, RESID:AA0382]
comment	Cross-link 2; carboxamidine; incidental to RESID:AA0183; incidental to RESID:AA0365.
synonym	"2-(3,4,5,6-tetrahydropyridin-2-yl)-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"2-(tetrahydropyrid-2-yl)-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"2-tetrahydropyridinyl-5-imidazolinone glycine" EXACT RESID-name []
synonym	"[5-oxo-2-(3,4,5,6-tetrahydropyridin-2-yl)-4,5-dihydro-1H-imidazol-1-yl]acetic acid" EXACT RESID-alternate []
synonym	"[5-oxo-2-(3,4,5,6-tetrahydropyridin-2-yl)-4,5-dihydro-1H-imidazol-1-yl]acetic acid" EXACT RESID-systematic []
synonym	"CROSSLNK 2-tetrahydro-2-pyridyl-5-imidazolinone (Lys-Gly)" EXACT UniProt-feature []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"Zoanthus sp. fluorescent protein zFP538 chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-37.06"
xref	DiffFormula: "C 0 H -7 N -1 O -1"
xref	DiffMono: "-37.052764"
xref	Formula: "C 8 H 9 N 2 O 1"
xref	MassAvg: "149.17"
xref	MassMono: "149.071488"
xref	Origin: "G, K"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.388. MOD:00388 L-alanyl-pentaglycyl-murein peptidoglycan

Table 390. Term [MOD:00388]
id	MOD:00388
name	L-alanyl-pentaglycyl-murein peptidoglycan
def	"A protein modification that effectively attaches an L-alanine residue to murein peptidoglycan by a pentaglycine linker peptide." [PubMed:8163519, RESID:AA0383]
synonym	"(2R,6S)-2-(N-mureinyl-®-alanyl-(S)-isoglutamyl)amino-6-(alanyl-pentaglycyl)amino-pimeloyl-(S)-alanyl-(S)-alanine" EXACT RESID-alternate []
synonym	"L-alanyl-pentaglycyl-murein peptidoglycan" EXACT RESID-name []
synonym	"MOD_RES Pentaglycyl murein peptidoglycan amidated alanine" EXACT UniProt-feature []
xref	DiffAvg: "268.25"
xref	DiffFormula: "C 10 H 14 N 5 O 4"
xref	DiffMono: "268.104579"
xref	Formula: "C 13 H 20 N 6 O 6"
xref	MassAvg: "356.34"
xref	MassMono: "356.144432"
xref	Origin: "A"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01159 peptidoglycanated residue ! peptidoglycanated residue

2.389. MOD:00389 N-formyl-L-proline

Table 391. Term [MOD:00389]
id	MOD:00389
name	N-formyl-L-proline
def	"A protein modification that effectively converts an L-proline residue to N-formyl-L-proline." [PubMed:12051774, PubMed:5464655, RESID:AA0384, UniMod:122#N-term]
comment	CAUTION - observations of this modification can be attributed to unintended artifactual production, or to spurious peptide MS identification. This modification is probably not a natural post-translational modification [JSG].
synonym	"(2S)-1-formylpyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"1-formyl-2-pyrrolidinecarboxylic acid" EXACT RESID-alternate []
synonym	"1-formylproline" EXACT RESID-alternate []
synonym	"N-formyl-L-proline" EXACT RESID-name []
synonym	"N-formylated L-proline" EXACT PSI-MOD-alternate []
synonym	"NFoPro" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 6 H 8 N 1 O 2"
xref	MassAvg: "126.14"
xref	MassMono: "126.055504"
xref	Origin: "P"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.390. MOD:00390 O-decanoyl-L-serine

Table 392. Term [MOD:00390]
id	MOD:00390
name	O-decanoyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-decanoyl-L-serine." [PubMed:12630926, RESID:AA0385, UniMod:449#S]
synonym	"(2S)-2-amino-3-(decanoyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"Decanoyl" RELATED PSI-MS-label []
synonym	"L-serine decanoate ester" EXACT RESID-alternate []
synonym	"lipid" RELATED UniMod-description []
synonym	"LIPID O-decanoyl serine" EXACT UniProt-feature []
synonym	"O-decanoyl-L-serine" EXACT RESID-name []
synonym	"O-decanoylated L-serine" EXACT PSI-MOD-alternate []
synonym	"O3-decanoyl-L-serine" EXACT RESID-alternate []
synonym	"ODecSer" EXACT PSI-MOD-label []
xref	DiffAvg: "154.25"
xref	DiffFormula: "C 10 H 18 N 0 O 1"
xref	DiffMono: "154.135765"
xref	Formula: "C 13 H 23 N 1 O 3"
xref	MassAvg: "241.33"
xref	MassMono: "241.167794"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00668 O-decanoylated residue ! O-decanoylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.391. MOD:00391 O-octanoyl-L-threonine

Table 393. Term [MOD:00391]
id	MOD:00391
name	O-octanoyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-octanoyl-L-threonine." [PubMed:11546772, PubMed:12716131, RESID:AA0386, UniMod:426#T]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(octanoyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"L-threonine octanoate ester" EXACT RESID-alternate []
synonym	"LIPID O-octanoyl threonine" EXACT UniProt-feature []
synonym	"O-octanoyl-L-threonine" EXACT RESID-name []
synonym	"O-octanoylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"O3-octanoyl-L-threonine" EXACT RESID-alternate []
synonym	"Octanoyl" RELATED PSI-MS-label []
synonym	"octanoyl" RELATED UniMod-description []
synonym	"OOctThr" EXACT PSI-MOD-label []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1"
xref	DiffMono: "126.104465"
xref	Formula: "C 12 H 21 N 1 O 3"
xref	MassAvg: "227.30"
xref	MassMono: "227.152144"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00669 O-octanoylated residue ! O-octanoylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.392. MOD:00392 O-decanoyl-L-threonine

Table 394. Term [MOD:00392]
id	MOD:00392
name	O-decanoyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-decanoyl-L-threonine." [PubMed:11546772, RESID:AA0387, UniMod:449#T]
synonym	"(2S)-2-amino-3-(decanoyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"Decanoyl" RELATED PSI-MS-label []
synonym	"L-threonine decanoate ester" EXACT RESID-alternate []
synonym	"lipid" RELATED UniMod-description []
synonym	"LIPID O-decanoyl threonine" EXACT UniProt-feature []
synonym	"O-decanoyl-L-threonine" EXACT RESID-name []
synonym	"O-decanoylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"O3-decanoyl-L-threonine" EXACT RESID-alternate []
synonym	"ODecThr" EXACT PSI-MOD-label []
xref	DiffAvg: "154.25"
xref	DiffFormula: "C 10 H 18 N 0 O 1"
xref	DiffMono: "154.135765"
xref	Formula: "C 14 H 25 N 1 O 3"
xref	MassAvg: "255.36"
xref	MassMono: "255.183444"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00668 O-decanoylated residue ! O-decanoylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.393. MOD:00393 O-methylated residue

Table 395. Term [MOD:00393]
id	MOD:00393
name	O-methylated residue
def	"A protein modification that effectively replaces a hydroxyl group hydrogen with a methyl group to produce either an ether from an alcohol or an ester from an acid." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OMeRes" EXACT PSI-MOD-label []
is_a	MOD:00427 methylated residue ! methylated residue

2.394. MOD:00394 acetylated residue

Table 396. Term [MOD:00394]
id	MOD:00394
name	acetylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an acetyl group." [DeltaMass:0, PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:14730666, PubMed:15350136, UniMod:1]
comment	Amino hydrogens are replaced to produce amides; hydroxyl hydrogens are replaced to produce esters; and hydrosulfanyl (thiol) hydrogens are replaced to produce sulfanyl esters (thiol esters). From DeltaMass: Average Mass: 42
subset	PSI-MOD-slim
synonym	"Acetyl" RELATED PSI-MS-label []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"Acetylation (N terminus, N epsilon of Lysine, O of Serine) (Ac)" EXACT DeltaMass-label []
synonym	"AcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.395. MOD:00395 thioester crosslinked residues

Table 397. Term [MOD:00395]
id	MOD:00395
name	thioester crosslinked residues
def	"A protein modification that crosslinks two residues by formation of a thioester bond between a cysteine thiol and either an alpha-carbonyl, as in S-(L-methionyl-L-cysteine), or a sidechain carbonyl, as in S-(L-isoglutamyl)-L-cysteine." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.396. MOD:00396 O-glycosylated residue

Table 398. Term [MOD:00396]
id	MOD:00396
name	O-glycosylated residue
def	"A protein modification that effectively replaces a residue hydrogen atom on an oxygen with a carbohydrate-like group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OGlycoRes" EXACT PSI-MOD-label []
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.397. MOD:00397 iodoacetamide derivatized residue

Table 399. Term [MOD:00397]
id	MOD:00397
name	iodoacetamide derivatized residue
def	"A protein modification that is produced by reaction with iodoacetamide, usually replacement of a reactive hydrogen with a methylcarboxamido group." [PubMed:11327326, PubMed:11510821, PubMed:12422359, UniMod:4]
subset	PSI-MOD-slim
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.398. MOD:00398 carbamoylated residue

Table 400. Term [MOD:00398]
id	MOD:00398
name	carbamoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a carbamoyl (carboxamido) group. Replacement of an amino hydrogen produces a ureido group." [DeltaMass:56, PubMed:10978403, PubMed:12203680, UniMod:5]
comment	This modification can be produced by hydrogen cyanate, either used as a reagent or as released by urea degradation in solution [JSG].
subset	PSI-MOD-slim
synonym	"Carbamyl" RELATED UniMod-interim []
synonym	"Carbamylation" EXACT DeltaMass-label []
synonym	"Carbamylation" RELATED UniMod-description []
xref	DiffAvg: "43.02"
xref	DiffFormula: "C 1 H 1 N 1 O 1"
xref	DiffMono: "43.005814"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.399. MOD:00399 iodoacetic acid derivatized residue

Table 401. Term [MOD:00399]
id	MOD:00399
name	iodoacetic acid derivatized residue
def	"A protein modification that is produced by reaction with iodoacetic acid, usually replacement of a reactive hydrogen with a methylcarboxy group." [DeltaMass:64, UniMod:6]
comment	From DeltaMass: Average Mass: 58 Abbreviation:CmC Average Mass Change:58 Notes:Cysteine reacts with iodoacetic acid to produce carboxymethyl cysteine.
subset	PSI-MOD-slim
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Carboxymethyl (on Cysteine)" EXACT DeltaMass-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.400. MOD:00400 deamidated residue

Table 402. Term [MOD:00400]
id	MOD:00400
name	deamidated residue
def	"A protein modification that effectively replaces a carboxamido group with a carboxyl group, with both a gain of oxygen and loss of a nitrogen and a hydrogen." [DeltaMass:32, OMSSA:4, UniMod:7]
comment	From DeltaMass: References:Vish Katta.
subset	PSI-MOD-slim
synonym	"Deamidated" RELATED PSI-MS-label []
synonym	"Deamidation" RELATED UniMod-description []
synonym	"Deamidation of Asparagine and Glutamine to Aspartate and Glutamate" EXACT DeltaMass-label []
synonym	"deamidationkq" EXACT OMSSA-label []
synonym	"dNRes" EXACT PSI-MOD-label []
xref	DiffAvg: "0.98"
xref	DiffFormula: "H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.401. MOD:00401 Gygi ICAT™ d0 modified cysteine

Table 403. Term [MOD:00401]
id	MOD:00401
name	Gygi ICAT™ d0 modified cysteine
def	"A protein modification that is produced by formation of an adduct of a cysteine residue with the Gygi isotope-coded affinity tag d0 reagent." [PubMed:10504701, UniMod:8#C]
synonym	"Gygi ICAT™ d0" RELATED UniMod-description []
synonym	"ICAT-G" RELATED PSI-MS-label []
xref	DiffAvg: "486.63"
xref	DiffFormula: "C 22 H 38 N 4 O 6 S 1"
xref	DiffMono: "486.251206"
xref	Formula: "C 25 H 43 N 5 O 7 S 2"
xref	MassAvg: "589.77"
xref	MassMono: "589.260391"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01820 isotope tagged sufhydryl reagent modified cysteine ! isotope tagged sufhydryl reagent modified cysteine

2.402. MOD:00402 Gygi ICAT™ d8 modified cysteine

Table 404. Term [MOD:00402]
id	MOD:00402
name	Gygi ICAT™ d8 modified cysteine
def	"A protein modification that is produced by formation of an adduct of a cysteine residue with the Gygi isotope-coded affinity tag d8 reagent." [PubMed:10504701, UniMod:9#C]
synonym	"Gygi ICAT™ d8" RELATED UniMod-description []
synonym	"ICAT-G:2H(8)" RELATED PSI-MS-label []
xref	DiffAvg: "494.30"
xref	DiffFormula: "C 22 (1)H 30 (2)H 8 N 4 O 6 S 1"
xref	DiffMono: "494.301420"
xref	Formula: "C 25 (1)H 35 (2)H 8 N 5 O 7 S 2"
xref	MassAvg: "597.31"
xref	MassMono: "597.310605"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent
is_a	MOD:01820 isotope tagged sufhydryl reagent modified cysteine ! isotope tagged sufhydryl reagent modified cysteine

2.403. MOD:00403 homoserine

Table 405. Term [MOD:00403]
id	MOD:00403
name	homoserine
def	"A protein modification that effectively converts an L-methionine residue to homoserine." [DeltaMass:113, OMSSA:56, UniMod:10#M]
comment	Usually formed from methionine by reaction with cyanogen bromide, CNBr, which cleaves the peptide at the methionine carboxyl group and the following residue amino group.
subset	PSI-MOD-slim
synonym	"ctermpephsem" EXACT OMSSA-label []
synonym	"Homoserine" RELATED UniMod-description []
synonym	"Homoserine formed from Met by CNBr treatment" EXACT DeltaMass-label []
synonym	"Met→Hse" RELATED PSI-MS-label []
xref	DiffAvg: "-30.09"
xref	DiffFormula: "C -1 H -2 O 1 S -1"
xref	DiffMono: "-29.992806"
xref	Formula: "C 4 H 7 N 1 O 2"
xref	MassAvg: "101.10"
xref	MassMono: "101.047678"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.404. MOD:00404 homoserine lactone

Table 406. Term [MOD:00404]
id	MOD:00404
name	homoserine lactone
def	"A protein modification that effectively converts an L-methionine residue to homoserine lactone." [DeltaMass:90, OMSSA:57, UniMod:11#M]
comment	Usually formed from methionine by reaction with cyanogen bromide, CNBr, which cleaves the peptide at the methionine carboxyl group. Under acid conditions the homoserine dehydrates to form the cyclic lactone.
subset	PSI-MOD-slim
synonym	"ctermpephselactm" EXACT OMSSA-label []
synonym	"Homoserine lactone" RELATED UniMod-description []
synonym	"Met→Hsl" RELATED UniMod-interim []
xref	DiffAvg: "-48.10"
xref	DiffFormula: "C -1 H -4 S -1"
xref	DiffMono: "-48.003371"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.405. MOD:00405 Applied Biosystems original ICAT™ d8 modified cysteine

Table 407. Term [MOD:00405]
id	MOD:00405
name	Applied Biosystems original ICAT™ d8 modified cysteine
def	"A protein modification that is produced by formation of an adduct of a cysteine residue with the Applied Biosystems original isotope-coded affinity tag d8 reagent." [UniMod:12#C]
subset	PSI-MOD-slim
synonym	"Applied Biosystems original ICAT™ d8" RELATED UniMod-description []
synonym	"ICAT-D:2H(8)" RELATED PSI-MS-label []
xref	DiffAvg: "450.28"
xref	DiffFormula: "C 20 (1)H 26 (2)H 8 N 4 O 5 S 1"
xref	DiffMono: "450.275205"
xref	Formula: "C 23 (1)H 31 (2)H 8 N 5 O 6 S 2"
xref	MassAvg: "553.28"
xref	MassMono: "553.284390"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent
is_a	MOD:01820 isotope tagged sufhydryl reagent modified cysteine ! isotope tagged sufhydryl reagent modified cysteine

2.406. MOD:00406 Applied Biosystems original ICAT™ d0 modified cysteine

Table 408. Term [MOD:00406]
id	MOD:00406
name	Applied Biosystems original ICAT™ d0 modified cysteine
def	"A protein modification that is produced by formation of an adduct of a cysteine residue with the Applied Biosystems original isotope-coded affinity tag d0 reagent." [UniMod:13#C]
subset	PSI-MOD-slim
synonym	"Applied Biosystems original ICAT™ d0" RELATED UniMod-description []
synonym	"ICAT-D" RELATED PSI-MS-label []
xref	DiffAvg: "442.22"
xref	DiffFormula: "C 20 (1)H 34 N 4 O 5 S 1"
xref	DiffMono: "442.224991"
xref	Formula: "C 23 (1)H 39 N 5 O 6 S 2"
xref	MassAvg: "545.23"
xref	MassMono: "545.234176"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01820 isotope tagged sufhydryl reagent modified cysteine ! isotope tagged sufhydryl reagent modified cysteine

2.407. MOD:00407 residue methyl ester

Table 409. Term [MOD:00407]
id	MOD:00407
name	residue methyl ester
def	"A protein modification that effectively replaces a carboxyl group with a carboxy methyl ester group. OBSOLETE because UniMod:14 merged with entry 34, remap to MOD:00599." [PubMed:18688235]
synonym	"ResOMe" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2"
xref	DiffMono: "14.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.408. MOD:00408 N-acetylated residue

Table 410. Term [MOD:00408]
id	MOD:00408
name	N-acetylated residue
def	"A protein modification that effectively replaces a residue amino or imino hydrogen with an acetyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"N-Acetyl" EXACT PSI-MOD-alternate []
synonym	"N-Acetylation" EXACT PSI-MOD-alternate []
synonym	"NAcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.409. MOD:00409 N-formylated residue

Table 411. Term [MOD:00409]
id	MOD:00409
name	N-formylated residue
def	"A protein modification that effectively replaces a residue amino group with a formamido group." [OMSSA:44, OMSSA:82]
subset	PSI-MOD-slim
synonym	"Formyl" RELATED PSI-MS-label []
synonym	"NFoRes" EXACT PSI-MOD-label []
synonym	"ntermformyl" EXACT OMSSA-label []
synonym	"ntermpepformyl" EXACT OMSSA-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00493 formylated residue ! formylated residue
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.410. MOD:00410 S-(N-isopropylcarboxamidomethyl)-L-cysteine

Table 412. Term [MOD:00410]
id	MOD:00410
name	S-(N-isopropylcarboxamidomethyl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(N-isopropylcarboxamidomethyl)-L-cysteine." [OMSSA:84, PubMed:11465505, PubMed:8465942, UniMod:17#C]
synonym	"N-isopropylcarboxamidomethyl" RELATED UniMod-description []
synonym	"NIPCAM" RELATED PSI-MS-label []
synonym	"nipcam" EXACT OMSSA-label []
xref	DiffAvg: "99.13"
xref	DiffFormula: "C 5 H 9 N 1 O 1 S 0"
xref	DiffMono: "99.068414"
xref	Formula: "C 8 H 14 N 2 O 2 S 1"
xref	MassAvg: "202.27"
xref	MassMono: "202.077599"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.411. MOD:00411 O18 label

Table 413. Term [MOD:00411]
id	MOD:00411
name	O18 label
def	"modification from UniMod Isotopic label. OBSOLETE because UniMod:18 is now merged with entry 258 remap to MOD:00581 'single 018 label'" [PubMed:18688235]
comment	A modification from UniMod:18
xref	DiffAvg: "2.00"
xref	DiffFormula: "(16)O -1 (18)O 1"
xref	DiffMono: "2.004246"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.412. MOD:00412 oxidation

Table 414. Term [MOD:00412]
id	MOD:00412
name	oxidation
def	"modification from UniMod artifact. OBSOLETE because UniMod entry 19 is now merged with UniMod 35 remap to MOD:00425 'monohydroxylated residue'." [PubMed:18688235]
xref	DiffAvg: "16.00"
xref	DiffFormula: "O 1"
xref	DiffMono: "15.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.413. MOD:00413 biotinyl-iodoacetamidyl-3,6-dioxaoctanediamine derivatized cysteine

Table 415. Term [MOD:00413]
id	MOD:00413
name	biotinyl-iodoacetamidyl-3,6-dioxaoctanediamine derivatized cysteine
def	"A protein modification that is produced by reaction of a cysteine residue with biotinyl-iodoacetamidyl-3,6-dioxaoctanediamine." [UniMod:20#C]
synonym	"Biotinyl-iodoacetamidyl-3,6-dioxaoctanediamine" RELATED UniMod-description []
synonym	"PEO-Iodoacetyl-LC-Biotin" RELATED UniMod-interim []
xref	DiffAvg: "414.52"
xref	DiffFormula: "C 18 H 30 N 4 O 5 S 1"
xref	DiffMono: "414.193691"
xref	Formula: "C 21 H 35 N 5 O 6 S 2"
xref	MassAvg: "517.66"
xref	MassMono: "517.202876"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.414. MOD:00414 monomethylated L-arginine

Table 416. Term [MOD:00414]
id	MOD:00414
name	monomethylated L-arginine
def	"A protein modification that effectively replaces one hydrogen atom of an L-arginine residue with one methyl group." [DeltaMass:215, OMSSA:77, UniMod:34#R]
comment	From DeltaMass: formula incorrect, N and O reversed
subset	PSI-MOD-slim
synonym	"Me1Arg" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methylr" EXACT OMSSA-label []
synonym	"N-methyl Arginyl" EXACT DeltaMass-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "R"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00658 methylated arginine ! methylated arginine

2.415. MOD:00415 phosphorylation without neutral loss

Table 417. Term [MOD:00415]
id	MOD:00415
name	phosphorylation without neutral loss
def	"modification from UniMod - OBSOLETE because UniMod entry 22 is now merged with entry 21 remap to MOD:00696 'phosphorylated residue'." [PubMed:18688235]
xref	DiffAvg: "79.98"
xref	DiffFormula: "H 1 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.416. MOD:00416 phosphorylation of an hydroxyl amino acid with prompt loss of phosphate

Table 418. Term [MOD:00416]
id	MOD:00416
name	phosphorylation of an hydroxyl amino acid with prompt loss of phosphate
def	"A change resulting in an alteration of the measured molecular mass of a peptide or protein hydroxyl amino acid phosphorylated promptly followed by secondary loss of a neutral trihydrogen phosphate molecular fragment." [UniMod:23]
comment	O4-phosphotyrosine does not lose phosphate by this mechanism. UniMod does not provide a citation for this particular modification [JSG].
subset	PSI-MOD-slim
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "H -2 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00432 modified residue with neutral loss of phosphate ! modified residue with neutral loss of phosphate
is_a	MOD:00704 dehydrated residue ! dehydrated residue

2.417. MOD:00417 S-carboxamidoethyl-L-cysteine

Table 419. Term [MOD:00417]
id	MOD:00417
name	S-carboxamidoethyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxamidoethyl-L-cysteine." [DeltaMass:72, OMSSA:5, PubMed:1481983, UniMod:24#C]
comment	From DeltaMass: References: Anal. Biochem. Vol 216 No. 1 p131 (citation not found) Notes: Residual acrylamide in SDS gels can label free cysteines to produce propionamido-Cys (also known as PAM-Cys)
synonym	"Acrylamide adduct" RELATED UniMod-description []
synonym	"PAM-Cys" EXACT DeltaMass-label []
synonym	"Propionamide" RELATED PSI-MS-label []
synonym	"Propionamide or Acrylamide adduct" EXACT DeltaMass-label []
synonym	"propionamidec" EXACT OMSSA-label []
synonym	"S-(3-amino-3-oxopropyl)cysteine" EXACT PSI-MOD-alternate []
synonym	"S-carbamoylethyl-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-propanamide-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "71.08"
xref	DiffFormula: "C 3 H 5 N 1 O 1 S 0"
xref	DiffMono: "71.037114"
xref	Formula: "C 6 H 10 N 2 O 2 S 1"
xref	MassAvg: "174.22"
xref	MassMono: "174.046299"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.418. MOD:00418 pyridylacetylated residue

Table 420. Term [MOD:00418]
id	MOD:00418
name	pyridylacetylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an (pyridin-3-yl)acetyl group." [PubMed:9276974, UniMod:25]
comment	Produced by reaction with N-[(pyrid-3-yl)acetyl]oxy-succinimide [JSG].
synonym	"Pyridylacetyl" RELATED PSI-MS-label []
synonym	"pyridylacetyl" RELATED UniMod-description []
xref	DiffAvg: "119.12"
xref	DiffFormula: "C 7 H 5 N 1 O 1"
xref	DiffMono: "119.037114"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.419. MOD:00419 ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid

Table 421. Term [MOD:00419]
id	MOD:00419
name	®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid
def	"A protein modification that effectively converts an L-cysteine residue to ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid." [DeltaMass:336, PubMed:12643538, UniMod:26#C]
comment	From DeltaMass: A secondary modification affecting peptides with S-carbamoylmethyl-L-cysteine (CamC) at the N-terminus. These exist in enzymatic digests of proteins that have been S-alkylated with iodoacetamide. Cyclization of N-terminal CamC gives a residue of ®-5-oxoperhydro-1,4-thiazine-3-carboxylic acid. Peptides in which this has occurred become more hydrophobic, and lose 17 Da from the N-terminal residue.
synonym	"®-5-oxoperhydro-1,4-thiazine-3-carboxylic acid" EXACT DeltaMass-label []
synonym	"5-oxothiomorpholine-3-carboxylic acid" EXACT PSI-MOD-alternate []
synonym	"Otc" EXACT DeltaMass-label []
synonym	"Pyro-carbamidomethyl" RELATED UniMod-interim []
synonym	"S-carbamoylmethylcysteine cyclization (N-terminus)" EXACT DeltaMass-label []
synonym	"S-carbamoylmethylcysteine cyclization (N-terminus)" RELATED UniMod-description []
xref	DiffAvg: "40.02"
xref	DiffFormula: "C 2 H 0 N 0 O 1 S 0"
xref	DiffMono: "39.994915"
xref	Formula: "C 5 H 6 N 1 O 2 S 1"
xref	MassAvg: "144.17"
xref	MassMono: "144.011924"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.420. MOD:00420 2-pyrrolidone-5-carboxylic acid (Glu)

Table 422. Term [MOD:00420]
id	MOD:00420
name	2-pyrrolidone-5-carboxylic acid (Glu)
def	"A protein modification that effectively converts an L-glutamic acid residue to 2-pyrrolidone-5-carboxylic acid." [DeltaMass:16, OMSSA:109, PubMed:10214721, PubMed:1836357, PubMed:3473473, PubMed:8382902, RESID:AA0031#GLU, UniMod:27#E]
comment	From DeltaMass: References: The conversion of glutamic acid to pyroglutamic was reported for the beta-amyloid protein. Miller et al. Arch. Biochem. Biophy. (1993) 301, 41-52 [DeltaMass]. The modification in amyloid protein is probably an artifact of treatment with strong acid under anhydrous conditions. Peptides with N-terminal glutamic acid isolated from single cells of Aplysia neurons show partial conversion to pyroglutamic acid, possibly dependent on a temperature sensitive factor [JSG].
synonym	"(2S)-5-oxo-2-pyrrolidinecarboxylic acid" EXACT RESID-systematic []
synonym	"2-oxopyrrolidine-5-carboxylic acid" EXACT RESID-alternate []
synonym	"2-pyrrolidone-5-carboxylic acid" EXACT RESID-name []
synonym	"5-oxoproline" EXACT RESID-alternate []
synonym	"5-oxopyrrolidine-2-carboxylic acid" EXACT RESID-alternate []
synonym	"5-pyrrolidone-2-carboxylic acid" EXACT RESID-alternate []
synonym	"Glu→pyro-Glu" RELATED PSI-MS-label []
synonym	"MOD_RES Pyrrolidone carboxylic acid (Glu)" EXACT UniProt-feature []
synonym	"ntermpeppyroe" EXACT OMSSA-label []
synonym	"PCA" EXACT RESID-alternate []
synonym	"PyrGlu(Glu)" EXACT PSI-MOD-label []
synonym	"Pyro-glu from E" RELATED UniMod-description []
synonym	"pyroglutamic acid" EXACT RESID-alternate []
synonym	"Pyroglutamic Acid formed from Glutamic Acid" EXACT DeltaMass-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 6 N 1 O 2"
xref	MassAvg: "112.11"
xref	MassMono: "112.039853"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01048 2-pyrrolidone-5-carboxylic acid ! 2-pyrrolidone-5-carboxylic acid

2.421. MOD:00421 C-glycosylated residue

Table 423. Term [MOD:00421]
id	MOD:00421
name	C-glycosylated residue
def	"A protein modification that effectively replaces a residue hydrogen atom on a carbon with a carbohydrate-like group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"CGlycoRes" EXACT PSI-MOD-label []
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.422. MOD:00422 alpha-amino morpholine-2-acetylated residue

Table 424. Term [MOD:00422]
id	MOD:00422
name	alpha-amino morpholine-2-acetylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a morpholine-2-acetyl group." [PubMed:10446193, UniMod:29#N-term]
comment	The UniMod name "N-Succinimidyl-3-morpholine acetate" appears to have been a typographical error [JSG].
synonym	"N-Succinimidyl-2-morpholine acetate" RELATED UniMod-description []
synonym	"N-succinimidylmorpholine-2-acetate alpha-amino derivative" EXACT PSI-MOD-alternate []
synonym	"SMA" RELATED PSI-MS-label []
xref	DiffAvg: "127.14"
xref	DiffFormula: "C 6 H 9 N 1 O 2"
xref	DiffMono: "127.063329"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue
is_a	MOD:01813 morpholine-2-acetylated residue ! morpholine-2-acetylated residue

2.423. MOD:00423 monosodium salt

Table 425. Term [MOD:00423]
id	MOD:00423
name	monosodium salt
def	"A protein modification that effectively substitutes one sodium atom for one hydrogen atom." [DeltaMass:0, UniMod:30]
subset	PSI-MOD-slim
synonym	"Cation:Na" RELATED PSI-MS-label []
synonym	"Na1Res" EXACT PSI-MOD-label []
synonym	"Sodium" EXACT DeltaMass-label []
synonym	"Sodium adduct" RELATED UniMod-description []
xref	DiffAvg: "21.98"
xref	DiffFormula: "H -1 Na 1"
xref	DiffMono: "21.981944"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00747 sodium containing modified residue ! sodium containing modified residue

2.424. MOD:00424 S-pyridylethyl-L-cysteine

Table 426. Term [MOD:00424]
id	MOD:00424
name	S-pyridylethyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-pyridylethyl-L-cysteine." [DeltaMass:253, OMSSA:112, PubMed:11760118, PubMed:626389, PubMed:8297018, PubMed:8783016, UniMod:31#C]
comment	From DeltaMass: Formula:C10H12O2N1S1 (formula incorrect, N and O reversed) Monoisotopic Mass Change:208.067 Average Mass Change:208.286 (mass incorrect, aggregate not delta) References:PE Sciex
synonym	"PECys" EXACT DeltaMass-label []
synonym	"Pyridylethyl" RELATED PSI-MS-label []
synonym	"Pyridylethyl Cystenyl" EXACT DeltaMass-label []
synonym	"S-pyridinylethyl-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-pyridylethylation" RELATED UniMod-description []
synonym	"spyridylethylc" EXACT OMSSA-label []
synonym	"vinylpyridine derivatized cysteine residue" EXACT PSI-MOD-alternate []
xref	DiffAvg: "105.14"
xref	DiffFormula: "C 7 H 7 N 1"
xref	DiffMono: "105.057849"
xref	Formula: "C 10 H 12 N 2 O 1 S 1"
xref	MassAvg: "208.28"
xref	MassMono: "208.067034"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.425. MOD:00425 monohydroxylated residue

Table 427. Term [MOD:00425]
id	MOD:00425
name	monohydroxylated residue
def	"A protein modification that effectively replaces one hydrogen atom with a hydroxyl group." [UniMod:35]
subset	PSI-MOD-slim
synonym	"Hy1Res" EXACT PSI-MOD-label []
synonym	"Oxidation" RELATED UniMod-interim []
synonym	"Oxidation or Hydroxylation" RELATED UniMod-description []
xref	DiffAvg: "16.00"
xref	DiffFormula: "O 1"
xref	DiffMono: "15.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "C-term"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue

2.426. MOD:00426 S-glycosylated residue

Table 428. Term [MOD:00426]
id	MOD:00426
name	S-glycosylated residue
def	"A protein modification that effectively replaces a residue hydrogen atom on a sulfur with a carbohydrate-like group through a glycosidic bond." [PubMed:18688235]
synonym	"SGlycoRes" EXACT PSI-MOD-label []
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.427. MOD:00427 methylated residue

Table 429. Term [MOD:00427]
id	MOD:00427
name	methylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a methyl group." [DeltaMass:36]
comment	From DeltaMass: Average Mass: 14 Average Mass Change:14 References:Methylation of Asparagine (found in phycobiliproteins) Klotz and Glazer (1987) J. Biol. Chem. 262; 17350-17355
subset	PSI-MOD-slim
synonym	"MeRes" EXACT PSI-MOD-label []
synonym	"Methylation (N terminus, N epsilon of Lysine, O of Serine, Threonine or C terminus, N of Asparagine)" EXACT DeltaMass-label []
is_a	MOD:00001 alkylated residue ! alkylated residue

2.428. MOD:00428 dihydroxylated residue

Table 430. Term [MOD:00428]
id	MOD:00428
name	dihydroxylated residue
def	"A protein modification that effectively replaces two hydrogen atoms with two hydroxyl groups." [PubMed:12686488, UniMod:425]
subset	PSI-MOD-slim
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"Hy2Res" EXACT PSI-MOD-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue

2.429. MOD:00429 dimethylated residue

Table 431. Term [MOD:00429]
id	MOD:00429
name	dimethylated residue
def	"A protein modification that effectively replaces two hydrogen atoms with two methyl groups." [DeltaMass:0, PubMed:12964758, PubMed:14570711, UniMod:36]
comment	For amino-terminal proline residues, dimethylation can effectively only be accomplished with a protonated imino group. This process accounts only for dimethylation and not protonation. The alternative Me2+Res process accounts for both protonation and dimethylation [JSG].
subset	PSI-MOD-slim
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"Me2Res" EXACT PSI-MOD-label []
synonym	"N,N dimethylation (of Arginine or Lysine)" EXACT DeltaMass-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue

2.430. MOD:00430 trimethylated residue

Table 432. Term [MOD:00430]
id	MOD:00430
name	trimethylated residue
def	"A protein modification that effectively replaces three hydrogen atoms with three methyl groups." [PubMed:12590383, PubMed:3145979, PubMed:4304194, PubMed:6778808, PubMed:7093227, PubMed:8453381, UniMod:37]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative Me3+Res process accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"Me3Res" EXACT PSI-MOD-label []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6"
xref	DiffMono: "42.046950"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue

2.431. MOD:00431 modified residue with a secondary neutral loss

Table 433. Term [MOD:00431]
id	MOD:00431
name	modified residue with a secondary neutral loss
def	"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue with a secondary loss of a neutral molecular fragment." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NLModRes" EXACT PSI-MOD-label []
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.432. MOD:00432 modified residue with neutral loss of phosphate

Table 434. Term [MOD:00432]
id	MOD:00432
name	modified residue with neutral loss of phosphate
def	"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue with a secondary loss of a neutral trihydrogen phosphate molecular fragment." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"dPhosModRes" EXACT PSI-MOD-label []
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss

2.433. MOD:00433 glucosylated residue

Table 435. Term [MOD:00433]
id	MOD:00433
name	glucosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an glucose group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"GlcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00434 hexosylated residue ! hexosylated residue
is_a	MOD:00726 glucosylated ! glucosylated

2.434. MOD:00434 hexosylated residue

Table 436. Term [MOD:00434]
id	MOD:00434
name	hexosylated residue
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a hexose sugar group through a glycosidic bond." [DeltaMass:203, PubMed:15279557, UniMod:41]
comment	From DeltaMass: Average Mass: 162 Formula:C6 H10 05 Monoisotopic Mass Change:162.053 Average Mass Change:162.143 References:PE Sciex.
subset	PSI-MOD-slim
synonym	"Hex" EXACT PSI-MOD-label []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
synonym	"Hexoses (Fru, Gal, Glc, Man)" EXACT DeltaMass-label []
synonym	"O-Glycosyl-" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.435. MOD:00435 O-phospho-L-serine with neutral loss of phosphate

Table 437. Term [MOD:00435]
id	MOD:00435
name	O-phospho-L-serine with neutral loss of phosphate
def	"Covalent modification of a peptide or protein amino acid phosphorylated serine with a secondary loss of a neutral trihydrogen phosphate molecular fragment." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"dPhosOPhosSer" EXACT PSI-MOD-label []
xref	DiffAvg: "-97.99"
xref	DiffFormula: "C 0 H -3 N 0 O -4 P -1"
xref	DiffMono: "-97.976895"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "MOD:00046"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01151 phosphorylated residue with neutral loss of phosphate ! phosphorylated residue with neutral loss of phosphate
relationship	derives_from MOD:00046 O-phospho-L-serine ! O-phospho-L-serine

2.436. MOD:00436 N-acetylhexosaminylated

Table 438. Term [MOD:00436]
id	MOD:00436
name	N-acetylhexosaminylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with an N-acetylhexosamine group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"HexNAc" EXACT PSI-MOD-label []
synonym	"N-Acetylhexosamine" RELATED UniMod-description []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.437. MOD:00437 farnesylated residue

Table 439. Term [MOD:00437]
id	MOD:00437
name	farnesylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a farnesyl group." [DeltaMass:0, PubMed:15609361, UniMod:44]
comment	From DeltaMass: Average Mass: 204
subset	PSI-MOD-slim
synonym	"Farnesyl" RELATED PSI-MS-label []
synonym	"Farnesylation" EXACT DeltaMass-label []
synonym	"Farnesylation" RELATED UniMod-description []
synonym	"FarnRes" EXACT PSI-MOD-label []
xref	DiffAvg: "204.36"
xref	DiffFormula: "C 15 H 24"
xref	DiffMono: "204.187801"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00703 isoprenylated residue ! isoprenylated residue

2.438. MOD:00438 myristoylated residue

Table 440. Term [MOD:00438]
id	MOD:00438
name	myristoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a myristoyl group." [DeltaMass:0, UniMod:45]
comment	From DeltaMass: Average Mass: 210
subset	PSI-MOD-slim
synonym	"C14:0 aliphatic acylated residue" EXACT PSI-MOD-alternate []
synonym	"Myristoyl" RELATED PSI-MS-label []
synonym	"Myristoylation" EXACT DeltaMass-label []
synonym	"Myristoylation" RELATED UniMod-description []
synonym	"MyrRes" EXACT PSI-MOD-label []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 O 1"
xref	DiffMono: "210.198365"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.439. MOD:00439 O-phospho-L-threonine with neutral loss of phosphate

Table 441. Term [MOD:00439]
id	MOD:00439
name	O-phospho-L-threonine with neutral loss of phosphate
def	"Covalent modification of a peptide or protein amino acid phosphorylated threonine with a secondary loss of a neutral trihydrogen phosphate molecular fragment." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"dPhosOPhosThr" EXACT PSI-MOD-label []
xref	DiffAvg: "-97.99"
xref	DiffFormula: "C 0 H -3 N 0 O -4 P -1"
xref	DiffMono: "-97.976895"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "MOD:00047"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01151 phosphorylated residue with neutral loss of phosphate ! phosphorylated residue with neutral loss of phosphate
relationship	derives_from MOD:00047 O-phospho-L-threonine ! O-phospho-L-threonine

2.440. MOD:00440 palmitoylated residue

Table 442. Term [MOD:00440]
id	MOD:00440
name	palmitoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a palmitoyl group." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 238
subset	PSI-MOD-slim
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" EXACT DeltaMass-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"PamRes" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.441. MOD:00441 geranylgeranylated residue

Table 443. Term [MOD:00441]
id	MOD:00441
name	geranylgeranylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a geranylgeranyl group." [DeltaMass:0, PubMed:15609361, UniMod:48]
comment	From DeltaMass: Average Mass: 272
subset	PSI-MOD-slim
synonym	"Geranyl-geranyl" RELATED UniMod-description []
synonym	"GeranylGeranyl" RELATED PSI-MS-label []
synonym	"Geranylgeranylation" EXACT DeltaMass-label []
synonym	"GergerRes" EXACT PSI-MOD-label []
xref	DiffAvg: "272.48"
xref	DiffFormula: "C 20 H 32"
xref	DiffMono: "272.250401"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00703 isoprenylated residue ! isoprenylated residue

2.442. MOD:00442 protonated omega-N,omega-N'-dimethylated L-arginine with secondary neutral loss of N,N'-carbodiimide

Table 444. Term [MOD:00442]
id	MOD:00442
name	protonated omega-N,omega-N'-dimethylated L-arginine with secondary neutral loss of N,N'-carbodiimide
def	"Covalent modification of a peptide or protein L-arginine residue to protonated omega-N,omega-N'-dimethylated L-arginine with secondary loss of an N,N'-carbodiimide molecular fragment." [PubMed:15835918, PubMed:18688235]
synonym	"dCDI-NNMe2+Arg" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 1 H 2 N 2 O 0"
xref	DiffMono: "42.021798"
xref	Formula: "C 7 H 14 N 2 O 1"
xref	MassAvg: "142.20"
xref	MassMono: "142.110613"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.443. MOD:00443 protonated omega-N,omega-N-dimethlyated L-arginine with secondary neutral loss of N,N-dimethylamine

Table 445. Term [MOD:00443]
id	MOD:00443
name	protonated omega-N,omega-N-dimethlyated L-arginine with secondary neutral loss of N,N-dimethylamine
def	"Covalent modification of a peptide or protein L-arginine residue to protonated omega-N,omega-N-dimethlyated L-arginine with secondary neutral loss of an N,N-dimethylamine molecular fragment." [PubMed:15835918, PubMed:18688235]
synonym	"dDMA-NoMe2+Arg" EXACT PSI-MOD-label []
xref	DiffAvg: "59.09"
xref	DiffFormula: "C 2 H 7 N 2"
xref	DiffMono: "59.060923"
xref	Formula: "C 6 H 10 N 3 O 1"
xref	MassAvg: "140.17"
xref	MassMono: "140.082387"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.444. MOD:00444 N-palmitoyl-S-(sn-1-2,3-dipalmitoyl-glycerol)cysteine

Table 446. Term [MOD:00444]
id	MOD:00444
name	N-palmitoyl-S-(sn-1-2,3-dipalmitoyl-glycerol)cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-S-(sn-1-2,3-dipalmitoyl-glycerol)cysteine." [OMSSA:118, PubMed:10356335, UniMod:51]
synonym	"N-acyl diglyceride cysteine" RELATED UniMod-description []
synonym	"ntermpeptripalmitatec" EXACT OMSSA-label []
synonym	"Tripalmitate" RELATED PSI-MS-label []
xref	DiffAvg: "789.32"
xref	DiffFormula: "C 51 H 96 O 5"
xref	DiffMono: "788.725776"
xref	Formula: "C 54 H 101 N 1 O 6 S 1"
xref	MassAvg: "892.46"
xref	MassMono: "891.734961"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00899 N-palmitoyl-S-diacylglycerol-L-cysteine ! N-palmitoyl-S-diacylglycerol-L-cysteine
relationship	has_functional_parent MOD:01144 S-(sn-1-2,3-dipalmitoylglycerol)-L-cysteine ! S-(sn-1-2,3-dipalmitoylglycerol)-L-cysteine

2.445. MOD:00445 L-homoarginine

Table 447. Term [MOD:00445]
id	MOD:00445
name	L-homoarginine
def	"A protein modification that effectively converts an L-lysine residue to L-homoarginine, such as reaction with O-methylisourea." [OMSSA:53, PubMed:11078590, PubMed:11085420, PubMed:11821862, UniMod:52]
subset	PSI-MOD-slim
synonym	"Guanidination" RELATED UniMod-description []
synonym	"guanidinationk" EXACT OMSSA-label []
synonym	"Guanidinyl" RELATED PSI-MS-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 1 H 2 N 2"
xref	DiffMono: "42.021798"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.446. MOD:00446 4-hydroxynonenal adduct

Table 448. Term [MOD:00446]
id	MOD:00446
name	4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of a residue with 4-hydroxynonenal." [PubMed:11327326, PubMed:15133838, UniMod:53]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"4-hydroxynonenal (HNE)" RELATED UniMod-description []
synonym	"HNE" RELATED PSI-MS-label []
xref	DiffAvg: "156.22"
xref	DiffFormula: "C 9 H 16 O 2"
xref	DiffMono: "156.115030"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.447. MOD:00447 N-glucuronylated residue

Table 449. Term [MOD:00447]
id	MOD:00447
name	N-glucuronylated residue
def	"A protein modification that effectively results from forming an adduct with a glucuronic acid either through a carboxyl group amide or ester bond, or through C1-glycosylation." [DeltaMass:0, PubMed:7398618, UniMod:54#N-term]
subset	PSI-MOD-slim
synonym	"Glucuronyl" RELATED PSI-MS-label []
synonym	"N-Glucuronyl (N terminus)" EXACT DeltaMass-label []
synonym	"N-glucuronylation" RELATED UniMod-description []
xref	DiffAvg: "176.12"
xref	DiffFormula: "C 6 H 8 O 6"
xref	DiffMono: "176.032088"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue

2.448. MOD:00448 N-acetylaminoglucosylated residue

Table 450. Term [MOD:00448]
id	MOD:00448
name	N-acetylaminoglucosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an N-acetylaminoglucose group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"GlcNAcRes" EXACT PSI-MOD-label []
synonym	"HexNAc" RELATED PSI-MS-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00733 N-acetylaminoglucosylated ! N-acetylaminoglucosylated
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.449. MOD:00449 acetate labeling reagent (N-term) (heavy form, +3amu)

Table 451. Term [MOD:00449]
id	MOD:00449
name	acetate labeling reagent (N-term) (heavy form, +3amu)
def	"modification from UniMod Isotopic label" [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:56]
synonym	"Acetate labeling reagent (N-term & K) (heavy form, +3amu)" RELATED UniMod-description []
synonym	"Acetyl:2H(3)" RELATED PSI-MS-label []
xref	DiffAvg: "45.03"
xref	DiffFormula: "C 2 (1)H -1 (2)H 3 O 1"
xref	DiffMono: "45.029395"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.450. MOD:00450 acetate labeling reagent light form (K)

Table 452. Term [MOD:00450]
id	MOD:00450
name	acetate labeling reagent light form (K)
def	"OBSOLETE because this isotopic label from UniMod entry 57 is deprecated" [PubMed:11857757]
xref	DiffAvg: "42.01"
xref	DiffFormula: "C 2 (1)H 2 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.451. MOD:00451 alpha-amino propanoylated residue

Table 453. Term [MOD:00451]
id	MOD:00451
name	alpha-amino propanoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a propanoyl group." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:58#N-term]
synonym	"Propionate labeling reagent light form (N-term & K)" RELATED UniMod-description []
synonym	"Propionyl" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01894 propanoylated residue ! propanoylated residue

2.452. MOD:00452 alpha-amino 3x(13)C-labeled propanoylated residue

Table 454. Term [MOD:00452]
id	MOD:00452
name	alpha-amino 3x(13)C-labeled propanoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a 3x(13)C-labeled propanoyl group." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:59#N-term]
synonym	"Propionate labeling reagent heavy form (+3amu), N-term & K" RELATED UniMod-description []
synonym	"Propionyl:13C(3)" RELATED PSI-MS-label []
xref	DiffAvg: "59.04"
xref	DiffFormula: "(13)C 3 H 4 O 1"
xref	DiffMono: "59.036279"
xref	Formula: "(12)C 6 (13)C 3 H 16 N 2 O 2"
xref	MassAvg: "187.13"
xref	MassMono: "187.131242"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00451 alpha-amino propanoylated residue ! alpha-amino propanoylated residue

2.453. MOD:00453 quaternary amine labeling reagent light form (N-term & K)

Table 455. Term [MOD:00453]
id	MOD:00453
name	quaternary amine labeling reagent light form (N-term & K)
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a quaternary amine reagent light form group." [PubMed:11857757, UniMod:60]
synonym	"GIST-Quat" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent light form (N-term & K)" RELATED UniMod-description []
xref	DiffAvg: "127.19"
xref	DiffFormula: "C 7 H 13 N 1 O 1"
xref	DiffMono: "127.099714"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.454. MOD:00454 quaternary amine labeling reagent heavy form (+3amu) (N-term & K)

Table 456. Term [MOD:00454]
id	MOD:00454
name	quaternary amine labeling reagent heavy form (+3amu) (N-term & K)
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a quaternary amine reagent heavy (+3amu) form group." [PubMed:11857757, UniMod:61]
synonym	"GIST-Quat:2H(3)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy (+3amu) form, N-term & K" RELATED UniMod-description []
xref	DiffAvg: "130.12"
xref	DiffFormula: "C 7 (1)H 10 (2)H 3 N 1 O 1"
xref	DiffMono: "130.118544"
xref	Formula: "C 13 (1)H 22 (2)H 3 N 3 O 2"
xref	MassAvg: "258.21"
xref	MassMono: "258.213507"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.455. MOD:00455 quaternary amine labeling reagent heavy form (+6amu) (N-term & K)

Table 457. Term [MOD:00455]
id	MOD:00455
name	quaternary amine labeling reagent heavy form (+6amu) (N-term & K)
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a quaternary amine reagent heavy (+6amu) form group." [PubMed:11857757, UniMod:62]
synonym	"GIST-Quat:2H(6)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy form (+6amu), N-term & K" RELATED UniMod-description []
xref	DiffAvg: "133.14"
xref	DiffFormula: "C 7 H 7 (2)H 6 N 1 O 1"
xref	DiffMono: "133.137375"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.456. MOD:00456 quaternary amine labeling reagent heavy form (+9amu) (N-term & K)

Table 458. Term [MOD:00456]
id	MOD:00456
name	quaternary amine labeling reagent heavy form (+9amu) (N-term & K)
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a quaternary amine reagent heavy (+9amu) form group." [PubMed:11857757, UniMod:63]
synonym	"GIST-Quat:2H(9)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy form (+9amu), N-term & K" RELATED UniMod-description []
xref	DiffAvg: "136.16"
xref	DiffFormula: "C 7 (1)H 4 (2)H 9 N 1 O 1"
xref	DiffMono: "136.156205"
xref	Formula: "C 13 (1)H 16 (2)H 9 N 3 O 2"
xref	MassAvg: "264.25"
xref	MassMono: "264.251168"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.457. MOD:00457 alpha-amino succinylated residue

Table 459. Term [MOD:00457]
id	MOD:00457
name	alpha-amino succinylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a succinyl group." [PubMed:11857757, PubMed:12175151, UniMod:64#N-term]
synonym	"Succinic anhydride labeling reagent light form (N-term)" RELATED UniMod-description []
synonym	"Succinyl" RELATED PSI-MS-label []
xref	DiffAvg: "100.02"
xref	DiffFormula: "(12)C 4 (1)H 4 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:01029 succinylated residue ! succinylated residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.458. MOD:00458 4x(2)H labeled alpha-amino succinylated residue

Table 460. Term [MOD:00458]
id	MOD:00458
name	4x(2)H labeled alpha-amino succinylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a 4x(2)H labeled succinyl group." [PubMed:11857757, PubMed:12175151, UniMod:65#N-term]
synonym	"Succinic anhydride labeling reagent, heavy form (+4amu, 4H2), N-term" RELATED UniMod-description []
synonym	"Succinyl:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "104.04"
xref	DiffFormula: "C 4 (2)H 4 O 3"
xref	DiffMono: "104.041151"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00457 alpha-amino succinylated residue ! alpha-amino succinylated residue

2.459. MOD:00459 4x(13)C labeled alpha-amino succinylated residue

Table 461. Term [MOD:00459]
id	MOD:00459
name	4x(13)C labeled alpha-amino succinylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a 4x(13)C labeled succinyl group." [PubMed:11857757, PubMed:12175151, UniMod:66#N-term]
synonym	"Succinic anhydride labeling reagent, heavy form (+4amu, 4C13), N-term & K" RELATED UniMod-description []
synonym	"Succinyl:13C(4)" RELATED PSI-MS-label []
xref	DiffAvg: "104.03"
xref	DiffFormula: "(13)C 4 H 4 O 3"
xref	DiffMono: "104.029463"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00457 alpha-amino succinylated residue ! alpha-amino succinylated residue

2.460. MOD:00460 L-cysteic acid (L-cysteine sulfonic acid)

Table 462. Term [MOD:00460]
id	MOD:00460
name	L-cysteic acid (L-cysteine sulfonic acid)
def	"A protein modification that effectively trioxygenates an L-cysteine residue to L-cysteine sulfonic acid." [ChEBI:17285, DeltaMass:334, OMSSA:34, PubMed:14678012, PubMed:18306178, PubMed:19522542, PubMed:9252331, RESID:AA0556, UniMod:345#C]
comment	From DeltaMass: Notes:Treatment of cysteine by strongly oxidising reagents such as performic acid results in the complete oxidation of the sulphur atom. Such treatment is often carried out prior to amino acid analysis as the resulting cysteic acid is then resistant to acid degradation during the hydrolysis procedure.
subset	PSI-MOD-slim
synonym	"(2R)-2-amino-3-sulfopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-2-carboxyethanesulfonic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-sulfopropanoic acid" EXACT RESID-alternate []
synonym	"3-sulfoalanine" EXACT RESID-alternate []
synonym	"Cya" EXACT DeltaMass-label []
synonym	"CysO3H" EXACT PSI-MOD-label []
synonym	"cysteic acid" EXACT RESID-alternate []
synonym	"Cysteic acid, oxidation of cysteine" EXACT DeltaMass-label []
synonym	"cysteicacidc" EXACT OMSSA-label []
synonym	"cysteine oxidation to cysteic acid" RELATED UniMod-description []
synonym	"cysteine sulphonic acid" EXACT RESID-alternate []
synonym	"L-cysteine sulfonic acid" EXACT RESID-name []
synonym	"Trioxidation" RELATED PSI-MS-label []
xref	DiffAvg: "48.00"
xref	DiffFormula: "C 0 H 0 N 0 O 3 S 0"
xref	DiffMono: "47.984744"
xref	Formula: "C 3 H 5 N 1 O 4 S 1"
xref	MassAvg: "151.14"
xref	MassMono: "150.993929"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine

2.461. MOD:00461 nitrosylation

Table 463. Term [MOD:00461]
id	MOD:00461
name	nitrosylation
def	"A protein modification that effectively substitutes a nitrite (NO2) group for a hydrogen atom." [DeltaMass:0, PubMed:8839040, PubMed:9252331, UniMod:354]
comment	Note, this is often misrepresented as the introduction of a nitrate (NO3) group [JSG].
subset	PSI-MOD-slim
synonym	"Nitro" RELATED PSI-MS-label []
synonym	"Nitro (NO2)" EXACT DeltaMass-label []
synonym	"Oxidation to nitro" RELATED UniMod-description []
xref	DiffAvg: "45.00"
xref	DiffFormula: "H -1 N 1 O 2"
xref	DiffMono: "44.985078"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.462. MOD:00462 L-kynurenine

Table 464. Term [MOD:00462]
id	MOD:00462
name	L-kynurenine
def	"A protein modification that effectively converts an L-tryptophan residue to L-kynurenine." [DeltaMass:357, OMSSA:66, PubMed:11029593, PubMed:9252331, UniMod:351#W]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-(2-aminophenyl)-4-oxo-butanoic acid" EXACT PSI-MOD-alternate []
synonym	"kynureninw" EXACT OMSSA-label []
synonym	"Trp→Kynurenin" RELATED PSI-MS-label []
synonym	"tryptophan oxidation to kynurenin" RELATED UniMod-description []
xref	DiffAvg: "3.99"
xref	DiffFormula: "C -1 O 1"
xref	DiffMono: "3.994915"
xref	Formula: "C 10 H 10 N 2 O 2"
xref	MassAvg: "190.20"
xref	MassMono: "190.074228"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.463. MOD:00463 3'-hydroxy-L-kynurenine

Table 465. Term [MOD:00463]
id	MOD:00463
name	3'-hydroxy-L-kynurenine
def	"A protein modification that effectively converts an L-tryptophan residue to 3'-hydroxy-L-kynurenine." [OMSSA:58, PubMed:9252331, UniMod:350#W]
subset	PSI-MOD-slim
synonym	"hydroxykynureninw" EXACT OMSSA-label []
synonym	"Trp→Hydroxykynurenin" RELATED PSI-MS-label []
synonym	"tryptophan oxidation to hydroxykynurenin" RELATED UniMod-description []
xref	DiffAvg: "19.99"
xref	DiffFormula: "C -1 O 2"
xref	DiffMono: "19.989829"
xref	Formula: "C 10 H 10 N 2 O 3"
xref	MassAvg: "206.20"
xref	MassMono: "206.069142"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.464. MOD:00464 N'-formyl-L-kynurenine

Table 466. Term [MOD:00464]
id	MOD:00464
name	N'-formyl-L-kynurenine
def	"A protein modification that effectively converts an L-tryptophan residue to N'-formyl-L-kynurenine." [DeltaMass:356, OMSSA:45, PubMed:12124932, PubMed:12686488, PubMed:9252331, UniMod:425#W]
comment	From DeltaMass: References:Willy V. Bienvenut, Catherine Déon, Carla Pasquarello, Jennifer M. Campbell, Jean-Charles Sanchez, Marvin L. Vestal, Denis F. Hochstrasser Matrix-assisted laser desorption/ionization-tandemmass spectrometry with high resolution andsensitivity for identification and characterizationof proteins. Proteomics 2002, 2, 868-876 Notes: A double oxidation of tryptophan for which the N-formylkynurenine (+32) structure can be proposed. Many minor peaks accompanying the main peak might also be attributed to other oxidation products of the tryptophan such as kynurenine (+4), an unknown by-product found in all oxidized tryptophan patterns (+13), hydroxytryptophan (+16), 3-hydroxykynurenine (+20) and hydroxy-N-formylkynurenine (+48). See proposed structures at http://www.abrf.org/images/misc/dmass32.jpg.
subset	PSI-MOD-slim
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
synonym	"Double oxidation of Trp" EXACT DeltaMass-label []
synonym	"formylkynureninw" EXACT OMSSA-label []
synonym	"tryptophan oxidation to formylkynurenin" RELATED UniMod-alternate []
xref	DiffAvg: "32.00"
xref	DiffFormula: "O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 11 H 10 N 2 O 3"
xref	MassAvg: "218.21"
xref	MassMono: "218.069142"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.465. MOD:00465 dihydroxyphenylalanine (Phe)

Table 467. Term [MOD:00465]
id	MOD:00465
name	dihydroxyphenylalanine (Phe)
def	"A protein modification that effectively converts an L-phenylalanine residue to a dihydroxyphenylalanine." [OMSSA:39, PubMed:1610822, PubMed:1903612, PubMed:3734192, PubMed:9252331, RESID:AA0146#var, UniMod:425#F]
comment	Dihydroxyphenyalanines with a 4'-hydroxyl orginate naturally by a monohydroxylation of tyrosine, and not by dihydroxylation of phenylalanine [JSG].
subset	PSI-MOD-slim
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"dihydroxyf" EXACT OMSSA-label []
synonym	"Dioxidation" RELATED PSI-MS-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 9 H 9 N 1 O 3"
xref	MassAvg: "179.17"
xref	MassMono: "179.058243"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.466. MOD:00466 glycosylsphingolipidinositolated residue

Table 468. Term [MOD:00466]
id	MOD:00466
name	glycosylsphingolipidinositolated residue
def	"A protein modification that effectively converts a residue to a glycosylsphingolipidinositolethanolamidated." [PubMed:12626404, PubMed:18688235, PubMed:8404891]
synonym	"GSIRes" EXACT PSI-MOD-label []
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.467. MOD:00467 iminobiotinyl modified residue

Table 469. Term [MOD:00467]
id	MOD:00467
name	iminobiotinyl modified residue
def	"A protein modification that effectively substitutes an iminobiotinyl group for a hydrogen atom." [PubMed:9750125, UniMod:89]
synonym	"Iminobiotin" RELATED PSI-MS-label []
synonym	"Iminobiotinylation" RELATED UniMod-description []
xref	DiffAvg: "225.31"
xref	DiffFormula: "C 10 H 15 N 3 O 1 S 1"
xref	DiffMono: "225.093583"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.468. MOD:00468 ESP-Tag light d0

Table 470. Term [MOD:00468]
id	MOD:00468
name	ESP-Tag light d0
def	"modification from UniMod Isotopic label" [UniMod:90]
synonym	"ESP" RELATED PSI-MS-label []
synonym	"ESP-Tag light d0" RELATED UniMod-description []
xref	DiffAvg: "338.47"
xref	DiffFormula: "C 16 H 26 N 4 O 2 S 1"
xref	DiffMono: "338.177647"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.469. MOD:00469 ESP-Tag heavy d10

Table 471. Term [MOD:00469]
id	MOD:00469
name	ESP-Tag heavy d10
def	"modification from UniMod Isotopic label" [UniMod:91]
synonym	"ESP-Tag heavy d10" RELATED UniMod-description []
synonym	"ESP:2H(10)" RELATED PSI-MS-label []
xref	DiffAvg: "348.24"
xref	DiffFormula: "C 16 (1)H 16 (2)H 10 N 4 O 2 S 1"
xref	DiffMono: "348.240415"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.470. MOD:00470 NHS-LC-Biotin

Table 472. Term [MOD:00470]
id	MOD:00470
name	NHS-LC-Biotin
def	"modification from UniMod Chemical derivative" [UniMod:92]
synonym	"NHS-LC-Biotin" RELATED UniMod-interim []
synonym	"NHS-LC-Biotin" RELATED UniMod-description []
xref	DiffAvg: "339.45"
xref	DiffFormula: "C 16 H 25 N 3 O 3 S 1"
xref	DiffMono: "339.161663"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.471. MOD:00471 EDT-maleimide-PEO-biotin

Table 473. Term [MOD:00471]
id	MOD:00471
name	EDT-maleimide-PEO-biotin
def	"modification from UniMod Chemical derivative" [UniMod:93]
synonym	"EDT-maleimide-PEO-biotin" RELATED UniMod-interim []
synonym	"EDT-maleimide-PEO-biotin" RELATED UniMod-description []
xref	DiffAvg: "601.80"
xref	DiffFormula: "C 25 H 39 N 5 O 6 S 3"
xref	DiffMono: "601.206247"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.472. MOD:00472 IMID d0

Table 474. Term [MOD:00472]
id	MOD:00472
name	IMID d0
def	"modification from UniMod Isotopic label" [PubMed:11746907, UniMod:94, URL:http\://dx.doi.org/10.1002/rcm.517]
synonym	"IMID" RELATED PSI-MS-label []
synonym	"IMID d0" RELATED UniMod-description []
xref	DiffAvg: "68.04"
xref	DiffFormula: "C 3 (1)H 4 N 2"
xref	DiffMono: "68.037448"
xref	Formula: "C 9 H 16 N 4 O 1"
xref	MassAvg: "196.13"
xref	MassMono: "196.132411"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.473. MOD:00473 IMID d4

Table 475. Term [MOD:00473]
id	MOD:00473
name	IMID d4
def	"modification from UniMod Isotopic label" [PubMed:11746907, UniMod:95, URL:http\://dx.doi.org/10.1002/rcm.517]
synonym	"IMID d4" RELATED UniMod-description []
synonym	"IMID:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "72.06"
xref	DiffFormula: "C 3 (2)H 4 N 2"
xref	DiffMono: "72.062555"
xref	Formula: "C 9 (1)H 12 (2)H 4 N 4 O 1"
xref	MassAvg: "200.16"
xref	MassMono: "200.157518"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.474. MOD:00474 S-([1,1,2-(2)H3]-carboxamidoethyl)-L-cysteine

Table 476. Term [MOD:00474]
id	MOD:00474
name	S-([1,1,2-(2)H3]-carboxamidoethyl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(1,1,2-(2)H3)-propanamide-L-cysteine." [UniMod:97#C]
synonym	"Acrylamide d3" RELATED UniMod-description []
synonym	"Propionamide:2H(3)" RELATED PSI-MS-label []
synonym	"S-([1,1,2-(2)H3]-3-amino-3-oxopropyl)cysteine" EXACT PSI-MOD-alternate []
synonym	"S-([1,1,2-(2)H3]-carbamoylethyl)-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-([1,1,2-(2)H3]-propanamide)-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "74.06"
xref	DiffFormula: "C 3 (1)H 2 (2)H 3 N 1 O 1"
xref	DiffMono: "74.055944"
xref	Formula: "C 6 (1)H 7 (2)H 3 N 2 O 2 S 1"
xref	MassAvg: "177.07"
xref	MassMono: "177.065129"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00417 S-carboxamidoethyl-L-cysteine ! S-carboxamidoethyl-L-cysteine
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.475. MOD:00475 tyrosine oxidation to 2-aminotyrosine

Table 477. Term [MOD:00475]
id	MOD:00475
name	tyrosine oxidation to 2-aminotyrosine
def	"modification from UniMod Chemical derivative" [PubMed:8839040, PubMed:9252331, UniMod:342#Y]
comment	May be misdescribed. Name (if not misdescribed) should be 2'-aminotyrosine [JSG].
synonym	"Amino" RELATED PSI-MS-label []
synonym	"Tyrosine oxidation to 2-aminotyrosine" RELATED UniMod-description []
xref	DiffAvg: "15.02"
xref	DiffFormula: "H 1 N 1"
xref	DiffMono: "15.010899"
xref	Formula: "C 9 H 10 N 2 O 2"
xref	MassAvg: "178.19"
xref	MassMono: "178.074228"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.476. MOD:00476 galactosylated residue

Table 478. Term [MOD:00476]
id	MOD:00476
name	galactosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an galactose group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"GalRes" EXACT PSI-MOD-label []
is_a	MOD:00434 hexosylated residue ! hexosylated residue
is_a	MOD:00728 galactosylated ! galactosylated

2.477. MOD:00477 2-pyrrolidone

Table 479. Term [MOD:00477]
id	MOD:00477
name	2-pyrrolidone
def	"A protein modification that effectively converts, by oxidative decarboxylation, an L-proline residue to 2-pyrrolidone with breakage of the peptide chain." [PubMed:2161657, PubMed:9252331, UniMod:360#P]
comment	The oxidative decarboxylation of a proline residue results in breaking of the peptide chain, leaving a peptidyl-2-pyrrolidone at the C-terminus. The difference formula, derived from the result in the original citation, has been corrected from the UniMod entry.
synonym	"Pro→Pyrrolidinone" RELATED PSI-MS-label []
synonym	"Proline oxidation to pyrrolidinone" RELATED UniMod-description []
xref	DiffAvg: "-13.02"
xref	DiffFormula: "C -1 H -1 N 0 O 0"
xref	DiffMono: "-13.007825"
xref	Formula: "C 4 H 6 N 1 O 1"
xref	MassAvg: "84.10"
xref	MassMono: "84.044939"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00683 dehydrogenated residue ! dehydrogenated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:00960 decarboxylated residue ! decarboxylated residue

2.478. MOD:00478 glutamyl semialdehyde (Pro)

Table 480. Term [MOD:00478]
id	MOD:00478
name	glutamyl semialdehyde (Pro)
def	"A protein modification that effectively converts an L-proline residue to L-glutamyl semialdehyde." [DeltaMass:354, PubMed:11120890, PubMed:2563380, PubMed:9252331, UniMod:35#P]
synonym	"gamma-glutamyl semialdehyde" EXACT PSI-MOD-alternate []
synonym	"glutamyl 5-semialdehyde" EXACT PSI-MOD-alternate []
synonym	"glutamyl aldehyde" EXACT PSI-MOD-alternate []
synonym	"Oxidation" RELATED UniMod-interim []
synonym	"Oxidation of proline to gamma-glutamyl semialdehyde" EXACT DeltaMass-label []
synonym	"Oxidation or Hydroxylation" RELATED UniMod-description []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01440 glutamyl semialdehyde ! glutamyl semialdehyde

2.479. MOD:00479 glutamyl semialdehyde (Arg)

Table 481. Term [MOD:00479]
id	MOD:00479
name	glutamyl semialdehyde (Arg)
def	"A protein modification that effectively converts an L-arginine residue to L-glutamyl semialdehyde." [DeltaMass:351, PubMed:11120890, PubMed:1680314, PubMed:9252331, UniMod:344#R]
comment	From DeltaMass: Average Mass: -27 Monoisotopic Mass Change:-27.06 Average Mass Change:-27.07 References:Amici A, Levine, RL, Tsai, L, and Stadtman, ER: Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions. Journal of Biological Chemistry 264: 3341-3346 1989.Requena JR, Chao CC, Levine RL, and Stadtman ER: Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins. Proceedings of the National Academy of Sciences USA 98: 69-74 2001.
synonym	"Arg→GluSA" RELATED PSI-MS-label []
synonym	"Arginine oxidation to glutamic semialdehyde" RELATED UniMod-description []
synonym	"Oxidation of arginine (to glutamic acid)" EXACT DeltaMass-label []
xref	DiffAvg: "-43.07"
xref	DiffFormula: "C -1 H -5 N -3 O 1"
xref	DiffMono: "-43.053433"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01440 glutamyl semialdehyde ! glutamyl semialdehyde

2.480. MOD:00480 Applied Biosystems cleavable ICAT™ light

Table 482. Term [MOD:00480]
id	MOD:00480
name	Applied Biosystems cleavable ICAT™ light
def	"modification from UniMod Isotopic label" [OMSSA:129, UniMod:105#C, URL:http\://www.appliedbiosystems.com/products/productdetail.cfm?prod_id=153]
subset	PSI-MOD-slim
synonym	"Applied Biosystems cleavable ICAT™ light" RELATED UniMod-description []
synonym	"ICAT-C" RELATED PSI-MS-label []
synonym	"icatlight" EXACT OMSSA-label []
xref	DiffAvg: "227.26"
xref	DiffFormula: "C 10 H 17 N 3 O 3"
xref	DiffMono: "227.126991"
xref	Formula: "C 13 H 22 N 4 O 4 S 1"
xref	MassAvg: "330.40"
xref	MassMono: "330.136176"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.481. MOD:00481 Applied Biosystems cleavable ICAT™ heavy

Table 483. Term [MOD:00481]
id	MOD:00481
name	Applied Biosystems cleavable ICAT™ heavy
def	"modification from UniMod Isotopic label" [OMSSA:130, UniMod:106#C, URL:http\://www.appliedbiosystems.com/products/productdetail.cfm?prod_id=153]
subset	PSI-MOD-slim
synonym	"Applied Biosystems cleavable ICAT™ heavy" RELATED UniMod-description []
synonym	"ICAT-C:13C(9)" RELATED PSI-MS-label []
synonym	"icatheavy" EXACT OMSSA-label []
xref	DiffAvg: "236.16"
xref	DiffFormula: "(12)C 1 (13)C 9 H 17 N 3 O 3"
xref	DiffMono: "236.157185"
xref	Formula: "(12)C 4 (13)C 9 H 22 N 4 O 4 S 1"
xref	MassAvg: "339.17"
xref	MassMono: "339.166370"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent

2.482. MOD:00482 N-formyl-L-methionine (Met)

Table 484. Term [MOD:00482]
id	MOD:00482
name	N-formyl-L-methionine (Met)
def	"A protein modification that effectively converts an L-methionine residue to N-formyl-L-methionine (not known as a natural, post-translational modification process)." [PubMed:11152118, PubMed:2165784, PubMed:3042771, RESID:AA0021#MET]
comment	This entry is for the artifactual formation of N-formyl-L-methionine from methionine. For encoded N-formyl-L-methionine, use MOD:00030 [JSG].
synonym	"(2S)-2-formylamino-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-formamido-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"2-formylamino-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"2-formylazanyl-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N-formylmethionine" EXACT UniProt-feature []
synonym	"N-formyl-L-methionine" EXACT RESID-name []
synonym	"N-formylated L-methionine" EXACT PSI-MOD-alternate []
synonym	"NFoMet" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1 S 0"
xref	DiffMono: "27.994915"
xref	Formula: "C 6 H 10 N 1 O 2 S 1"
xref	MassAvg: "160.21"
xref	MassMono: "160.043225"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00030 N-formyl-L-methionine residue ! N-formyl-L-methionine residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.483. MOD:00483 N-ethylmaleimide derivatized cysteine

Table 485. Term [MOD:00483]
id	MOD:00483
name	N-ethylmaleimide derivatized cysteine
def	"A protein modification that is produced by reaction with N-ethylmaleimide." [OMSSA:83, PubMed:11813307, PubMed:12777388, UniMod:108#C]
synonym	"N-ethylmaleimide on cysteines" RELATED UniMod-description []
synonym	"nemc" EXACT OMSSA-label []
synonym	"Nethylmaleimide" RELATED PSI-MS-label []
xref	DiffAvg: "125.13"
xref	DiffFormula: "C 6 H 7 N 1 O 2"
xref	DiffMono: "125.047678"
xref	Formula: "C 9 H 12 N 2 O 3 S 1"
xref	MassAvg: "228.27"
xref	MassMono: "228.056863"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.484. MOD:00484 oxidized lysine biotinylated with biotin-LC-hydrazide, reduced

Table 486. Term [MOD:00484]
id	MOD:00484
name	oxidized lysine biotinylated with biotin-LC-hydrazide, reduced
def	"modification from UniMod Chemical derivative" [UniMod:112#K]
synonym	"Oxidized lysine biotinylated with biotin-LC-hydrazide, reduced" RELATED UniMod-description []
synonym	"OxLysBiotinRed" RELATED UniMod-interim []
xref	DiffAvg: "354.47"
xref	DiffFormula: "C 16 H 26 N 4 O 3 S 1"
xref	DiffMono: "354.172562"
xref	Formula: "C 22 H 38 N 6 O 4 S 1"
xref	MassAvg: "482.64"
xref	MassMono: "482.267525"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.485. MOD:00485 oxidized lysine biotinylated with biotin-LC-hydrazide

Table 487. Term [MOD:00485]
id	MOD:00485
name	oxidized lysine biotinylated with biotin-LC-hydrazide
def	"modification from UniMod Chemical derivative" [UniMod:113#K]
synonym	"Oxidized lysine biotinylated with biotin-LC-hydrazide" RELATED UniMod-description []
synonym	"OxLysBiotin" RELATED UniMod-interim []
xref	DiffAvg: "352.45"
xref	DiffFormula: "C 16 H 24 N 4 O 3 S 1"
xref	DiffMono: "352.156912"
xref	Formula: "C 22 H 36 N 6 O 4 S 1"
xref	MassAvg: "480.63"
xref	MassMono: "480.251875"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.486. MOD:00486 oxidized proline biotinylated with biotin-LC-hydrazide, reduced

Table 488. Term [MOD:00486]
id	MOD:00486
name	oxidized proline biotinylated with biotin-LC-hydrazide, reduced
def	"modification from UniMod Chemical derivative" [UniMod:114#C]
synonym	"Oxidized proline biotinylated with biotin-LC-hydrazide, reduced" RELATED UniMod-description []
synonym	"OxProBiotinRed" RELATED UniMod-interim []
xref	DiffAvg: "371.50"
xref	DiffFormula: "C 16 H 29 N 5 O 3 S 1"
xref	DiffMono: "371.199111"
xref	Formula: "C 21 H 36 N 6 O 4 S 1"
xref	MassAvg: "468.62"
xref	MassMono: "468.251875"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.487. MOD:00487 oxidized proline biotinylated with biotin-LC-hydrazide

Table 489. Term [MOD:00487]
id	MOD:00487
name	oxidized proline biotinylated with biotin-LC-hydrazide
def	"modification from UniMod Chemical derivative" [UniMod:115#C]
synonym	"Oxidized Proline biotinylated with biotin-LC-hydrazide" RELATED UniMod-description []
synonym	"OxProBiotin" RELATED UniMod-interim []
xref	DiffAvg: "369.48"
xref	DiffFormula: "C 16 H 27 N 5 O 3 S 1"
xref	DiffMono: "369.183461"
xref	Formula: "C 21 H 34 N 6 O 4 S 1"
xref	MassAvg: "466.60"
xref	MassMono: "466.236225"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.488. MOD:00488 oxidized arginine biotinylated with biotin-LC-hydrazide

Table 490. Term [MOD:00488]
id	MOD:00488
name	oxidized arginine biotinylated with biotin-LC-hydrazide
def	"modification from UniMod Chemical derivative" [UniMod:116#C]
synonym	"OxArgBiotin" RELATED UniMod-interim []
synonym	"Oxidized arginine biotinylated with biotin-LC-hydrazide" RELATED UniMod-description []
xref	DiffAvg: "310.41"
xref	DiffFormula: "C 15 H 22 N 2 O 3 S 1"
xref	DiffMono: "310.135114"
xref	Formula: "C 21 H 34 N 6 O 4 S 1"
xref	MassAvg: "466.60"
xref	MassMono: "466.236225"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.489. MOD:00489 oxidized arginine biotinylated with biotin-LC-hydrazide, reduced

Table 491. Term [MOD:00489]
id	MOD:00489
name	oxidized arginine biotinylated with biotin-LC-hydrazide, reduced
def	"modification from UniMod Chemical derivative" [UniMod:117#C]
synonym	"OxArgBiotinRed" RELATED UniMod-interim []
synonym	"Oxidized arginine biotinylated with biotin-LC-hydrazide, reduced" RELATED UniMod-description []
xref	DiffAvg: "312.43"
xref	DiffFormula: "C 15 H 24 N 2 O 3 S 1"
xref	DiffMono: "312.150764"
xref	Formula: "C 21 H 36 N 6 O 4 S 1"
xref	MassAvg: "468.62"
xref	MassMono: "468.251875"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.490. MOD:00490 EDT-iodo-PEO-biotin

Table 492. Term [MOD:00490]
id	MOD:00490
name	EDT-iodo-PEO-biotin
def	"modification from UniMod Chemical derivative" [UniMod:118]
synonym	"EDT-iodo-PEO-biotin" RELATED UniMod-description []
synonym	"EDT-iodoacetyl-PEO-biotin" RELATED PSI-MS-label []
xref	DiffAvg: "490.70"
xref	DiffFormula: "C 20 H 34 N 4 O 4 S 3"
xref	DiffMono: "490.174219"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.491. MOD:00491 thio ether formation - BTP Adduct

Table 493. Term [MOD:00491]
id	MOD:00491
name	thio ether formation - BTP Adduct
def	"modification from UniMod Chemical derivative" [PubMed:11861642, UniMod:119#C]
synonym	"IBTP" RELATED PSI-MS-label []
synonym	"Thio Ether Formation - BTP Adduct" RELATED UniMod-description []
xref	DiffAvg: "316.38"
xref	DiffFormula: "C 22 H 21 P 1"
xref	DiffMono: "316.138087"
xref	Formula: "C 25 H 26 N 1 O 1 P 1 S 1"
xref	MassAvg: "419.52"
xref	MassMono: "419.147272"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.492. MOD:00492 ubiquitination signature dipeptidyl lysine

Table 494. Term [MOD:00492]
id	MOD:00492
name	ubiquitination signature dipeptidyl lysine
def	"A protein modification that crosslinks the N6-amino of a peptidyl lysine with the carboxyl of glycylglycine, the two glycine residues left after tryptic digestion of ubiquitin." [OMSSA:52, PubMed:11125103, PubMed:12612601, PubMed:12872131, RESID:AA0125#var, UniMod:121#K]
synonym	"GlyGly" RELATED PSI-MS-label []
synonym	"glyglyk" EXACT OMSSA-label []
synonym	"N6-(glycylglycyl)lysine" EXACT PSI-MOD-alternate []
synonym	"N6-glycylglycyl-L-lysine" EXACT PSI-MOD-alternate []
synonym	"ubiquitinylation residue" RELATED UniMod-description []
xref	DiffAvg: "114.10"
xref	DiffFormula: "C 4 H 6 N 2 O 2"
xref	DiffMono: "114.042927"
xref	Formula: "C 10 H 18 N 4 O 3"
xref	MassAvg: "242.28"
xref	MassMono: "242.137890"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
relationship	derives_from MOD:01148 ubiquitinylated lysine ! ubiquitinylated lysine

2.493. MOD:00493 formylated residue

Table 495. Term [MOD:00493]
id	MOD:00493
name	formylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a formyl group." [DeltaMass:0, PubMed:15799070, UniMod:122]
comment	From DeltaMass: Average Mass: 28
subset	PSI-MOD-slim
synonym	"FoRes" EXACT PSI-MOD-label []
synonym	"Formyl" RELATED PSI-MS-label []
synonym	"Formylation" RELATED UniMod-description []
synonym	"Formylation (CHO)" EXACT DeltaMass-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.494. MOD:00494 N-iodoacetyl, p-chlorobenzyl-12C6-glucamine

Table 496. Term [MOD:00494]
id	MOD:00494
name	N-iodoacetyl, p-chlorobenzyl-12C6-glucamine
def	"modification from UniMod Isotopic label" [PubMed:12185208, UniMod:123#C]
synonym	"ICAT-H" RELATED PSI-MS-label []
synonym	"N-iodoacetyl, p-chlorobenzyl-12C6-glucamine" RELATED UniMod-description []
xref	DiffAvg: "345.78"
xref	DiffFormula: "C 15 Cl 1 H 20 N 1 O 6 S 0"
xref	DiffMono: "345.097915"
xref	Formula: "C 18 Cl 1 H 25 N 2 O 7 S 1"
xref	MassAvg: "448.91"
xref	MassMono: "448.107100"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.495. MOD:00495 N-iodoacetyl, p-chlorobenzyl-13C6-glucamine

Table 497. Term [MOD:00495]
id	MOD:00495
name	N-iodoacetyl, p-chlorobenzyl-13C6-glucamine
def	"modification from UniMod Isotopic label" [PubMed:12185208, UniMod:124#C]
synonym	"ICAT-H:13C(6)" RELATED PSI-MS-label []
synonym	"N-iodoacetyl, p-chlorobenzyl-13C6-glucamine" RELATED UniMod-description []
xref	DiffAvg: "351.12"
xref	DiffFormula: "(12)C 9 (13)C 6 Cl 1 H 20 N 1 O 6 S 0"
xref	DiffMono: "351.118044"
xref	Formula: "(12)C 12 (13)C 6 Cl 1 H 25 N 2 O 7 S 1"
xref	MassAvg: "454.13"
xref	MassMono: "454.127229"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.496. MOD:00496 reductive amination-D

Table 498. Term [MOD:00496]
id	MOD:00496
name	reductive amination-D
def	"OBSOLETE because UniMod entry 125 is merged with entry 199, remap to id: MOD:00552" [UniMod:125]
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 2 (2)H 4"
xref	DiffMono: "32.056407"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.497. MOD:00497 3-sulfanylpropanoyl (N-term and Lys)

Table 499. Term [MOD:00497]
id	MOD:00497
name	3-sulfanylpropanoyl (N-term and Lys)
def	"modification from UniMod [(35)S]dithiobis(succinimidyl propionate) crosslinking" [PubMed:957432, UniMod:126]
comment	The name "thioacylation of primary amines" in UniMod was a misdescription [JSG].
synonym	"3,3-Dithio-bis-(sulfosuccinimidyl)propionate" RELATED UniMod-alternate []
synonym	"3-sulfanylpropanoyl" RELATED UniMod-description []
synonym	"Thioacyl" RELATED PSI-MS-label []
xref	DiffAvg: "88.12"
xref	DiffFormula: "C 3 H 4 O 1 S 1"
xref	DiffMono: "87.998286"
xref	Formula: "C 9 H 16 N 2 O 2 S 1"
xref	MassAvg: "216.30"
xref	MassMono: "216.093249"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.498. MOD:00498 fluorinated residue

Table 500. Term [MOD:00498]
id	MOD:00498
name	fluorinated residue
def	"A protein modification that effectively substitutes a hydrogen of a residue with a fluorine atom." [PubMed:18688235]
synonym	"Fluoro" RELATED PSI-MS-label []
synonym	"fluorophenylalanine replacement of phenylalanine" RELATED UniMod-description []
synonym	"Fluorophenylalanyl" EXACT DeltaMass-label []
synonym	"FRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue

2.499. MOD:00499 5-iodoacetamidofluorescein

Table 501. Term [MOD:00499]
id	MOD:00499
name	5-iodoacetamidofluorescein
def	"modification from UniMod Chemical derivative" [PubMed:3311742, PubMed:3578767, UniMod:128#C]
synonym	"5-Iodoacetamidofluorescein (Molecular Probe, Eugene, OR)" RELATED UniMod-description []
synonym	"Fluorescein" RELATED PSI-MS-label []
xref	DiffAvg: "388.35"
xref	DiffFormula: "C 22 H 14 N 1 O 6"
xref	DiffMono: "388.082112"
xref	Formula: "C 25 H 19 N 2 O 7 S 1"
xref	MassAvg: "491.49"
xref	MassMono: "491.091297"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.500. MOD:00500 monoiodinated residue

Table 502. Term [MOD:00500]
id	MOD:00500
name	monoiodinated residue
def	"A protein modification that effectively substitutes one hydrogen atom of a residue with one iodine atom." [DeltaMass:0, PubMed:15627961, PubMed:2026710, UniMod:129]
comment	From DeltaMass: Average Mass: 126
subset	PSI-MOD-slim
synonym	"I1Res" EXACT PSI-MOD-label []
synonym	"Iodination" RELATED UniMod-description []
synonym	"Iodination (of Histidine[C4] or Tyrosine[C3])" EXACT DeltaMass-label []
synonym	"Iodo" RELATED PSI-MS-label []
xref	DiffAvg: "125.90"
xref	DiffFormula: "H -1 I 1"
xref	DiffMono: "125.896648"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00755 iodinated residue ! iodinated residue

2.501. MOD:00501 diiodinated residue

Table 503. Term [MOD:00501]
id	MOD:00501
name	diiodinated residue
def	"A protein modification that effectively substitutes two hydrogen atoms of a residue with two iodine atoms." [UniMod:130]
comment	From DeltaMass: Average Mass: 252
subset	PSI-MOD-slim
synonym	"di-Iodination" RELATED UniMod-description []
synonym	"Diiodo" RELATED PSI-MS-label []
synonym	"I2Res" EXACT PSI-MOD-label []
xref	DiffAvg: "251.79"
xref	DiffFormula: "H -2 I 2"
xref	DiffMono: "251.793295"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00755 iodinated residue ! iodinated residue

2.502. MOD:00502 triiodinated residue

Table 504. Term [MOD:00502]
id	MOD:00502
name	triiodinated residue
def	"A protein modification that effectively substitutes three hydrogen atoms of a residue with three iodine atoms." [OMSSA:116, PubMed:15627961, PubMed:2026710, UniMod:131]
comment	From UniMod. In PubMed:2026710, mono- and diiodination of tyrosine are discussed, but triiodination of tyrosine is not mentioned. In PubMed:15627961, triiodothyronine (see MOD:00186) is discussed, but triiodotyrosine is not mentioned. This modification probably does not exist, and may be a confusion of "tyrosine" for "thyronine", a common error [JSG].
subset	PSI-MOD-slim
synonym	"I3Res" EXACT PSI-MOD-label []
synonym	"tri-Iodination" RELATED UniMod-description []
synonym	"triiodinationy" EXACT OMSSA-label []
synonym	"Triiodo" RELATED PSI-MS-label []
xref	DiffAvg: "377.69"
xref	DiffFormula: "H -3 I 3"
xref	DiffMono: "377.689943"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00755 iodinated residue ! iodinated residue

2.503. MOD:00503 N-(cis-delta 5)-tetradecaenoylglycine

Table 505. Term [MOD:00503]
id	MOD:00503
name	N-(cis-delta 5)-tetradecaenoylglycine
def	"A protein modification that effectively converts a glycine residue to N-(cis-delta 5)-tetradecaenoylglycine." [OMSSA:78, PubMed:11955007, PubMed:11955008, PubMed:1326520, PubMed:1386601, PubMed:6436247, PubMed:7543369, RESID:AA0059#var, UniMod:134#G]
synonym	"(cis-delta 5)-tetradecaenoyl" RELATED UniMod-description []
synonym	"Myristoleyl" RELATED PSI-MS-label []
synonym	"myristoleylation (one double bond)" EXACT DeltaMass-label []
synonym	"N-(C14:1 aliphatic acyl)glycine" EXACT PSI-MOD-alternate []
synonym	"ntermpepmyristoyeylationg" EXACT OMSSA-label []
xref	DiffAvg: "208.35"
xref	DiffFormula: "C 14 H 24 N 0 O 1"
xref	DiffMono: "208.182715"
xref	Formula: "C 16 H 27 N 1 O 2"
xref	MassAvg: "265.40"
xref	MassMono: "265.204179"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.504. MOD:00504 N-(cis,cis-delta 5,delta 8)-tetradecadienoylglycine

Table 506. Term [MOD:00504]
id	MOD:00504
name	N-(cis,cis-delta 5,delta 8)-tetradecadienoylglycine
def	"A protein modification that effectively converts a glycine residue to N-(cis,cis-delta 5,delta 8)-tetradecadienoylglycine." [OMSSA:79, PubMed:11955007, PubMed:11955008, PubMed:1326520, PubMed:1386601, PubMed:6436247, PubMed:7543369, RESID:AA0059#var, UniMod:135#G]
synonym	"(cis,cis-delta 5, delta 8)-tetradecadienoyl" RELATED UniMod-description []
synonym	"Myristoyl+Delta:H(-4)" RELATED PSI-MS-label []
synonym	"myristoylation-4H (two double bonds)" EXACT DeltaMass-label []
synonym	"N-(C14:2 aliphatic acyl)glycine" EXACT PSI-MOD-alternate []
synonym	"ntermpepmyristoyl4hg" EXACT OMSSA-label []
xref	DiffAvg: "206.33"
xref	DiffFormula: "C 14 H 22 O 1"
xref	DiffMono: "206.167065"
xref	Formula: "C 16 H 25 N 1 O 2"
xref	MassAvg: "263.38"
xref	MassMono: "263.188529"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.505. MOD:00505 benzoyl labeling reagent light form (N-term and K)

Table 507. Term [MOD:00505]
id	MOD:00505
name	benzoyl labeling reagent light form (N-term and K)
def	"modification from UniMod Isotopic label" [DeltaMass:0, PubMed:15456300, UniMod:136]
comment	From DeltaMass: Average Mass: 104
synonym	"Benzoyl" RELATED PSI-MS-label []
synonym	"Benzoyl (Bz)" EXACT DeltaMass-label []
synonym	"labeling reagent light form (N-term & K)" RELATED UniMod-description []
xref	DiffAvg: "104.11"
xref	DiffFormula: "C 7 H 4 O 1"
xref	DiffMono: "104.026215"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.506. MOD:00506 N-linked glycan core

Table 508. Term [MOD:00506]
id	MOD:00506
name	N-linked glycan core
def	"modification from UniMod N-linked glycosylation, Hex(5) HexNAc(2)" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:137#N]
synonym	"Hex(5)HexNAc(2)" RELATED PSI-MS-label []
synonym	"N-linked glycan core" RELATED UniMod-description []
xref	DiffAvg: "1217.09"
xref	DiffFormula: "C 46 H 76 N 2 O 35"
xref	DiffMono: "1216.422862"
xref	Formula: "C 50 H 82 N 4 O 37"
xref	MassAvg: "1331.20"
xref	MassMono: "1330.465790"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.507. MOD:00507 5-dimethylaminonaphthalene-1-sulfonyl

Table 509. Term [MOD:00507]
id	MOD:00507
name	5-dimethylaminonaphthalene-1-sulfonyl
def	"OBSOLETE because redundant, replaced by MOD:01653. Remap to MOD:01653." [DeltaMass:0, UniMod:139]
comment	From DeltaMass: Average Mass: 233
synonym	"5-dimethylaminonaphthalene-1-sulfonyl" RELATED UniMod-description []
synonym	"Dansyl" RELATED PSI-MS-label []
synonym	"Dansyl (Dns)" EXACT DeltaMass-label []
xref	DiffAvg: "233.29"
xref	DiffFormula: "C 12 H 11 N 1 O 2 S 1"
xref	DiffMono: "233.051050"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.508. MOD:00508 ISD a-series (C-Term)

Table 510. Term [MOD:00508]
id	MOD:00508
name	ISD a-series (C-Term)
def	"modification from UniMod Other" [PubMed:14588022, UniMod:140]
comment	Virtual Modification for MS/MS of a-type ions, by decarboxylation of C-terminus as reaction inside the mass spectrometer.
synonym	"a-type-ion" RELATED PSI-MS-label []
synonym	"ISD a-series (C-Term)" RELATED UniMod-description []
xref	DiffAvg: "-29.02"
xref	DiffFormula: "C -1 H -1 O -1"
xref	DiffMono: "-29.002740"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00003 UniMod ! UniMod

2.509. MOD:00509 amidination of lysines or N-terminal amines with methyl acetimidate

Table 511. Term [MOD:00509]
id	MOD:00509
name	amidination of lysines or N-terminal amines with methyl acetimidate
def	"modification from UniMod Chemical derivative" [PubMed:12643539, PubMed:6273432, UniMod:141]
synonym	"amidination of lysines or N-terminal amines with methyl acetimidate" RELATED UniMod-description []
synonym	"Amidine" RELATED PSI-MS-label []
xref	DiffAvg: "41.05"
xref	DiffFormula: "C 2 H 3 N 1"
xref	DiffMono: "41.026549"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.510. MOD:00510 HexNAc1dHex1

Table 512. Term [MOD:00510]
id	MOD:00510
name	HexNAc1dHex1
def	"modification from UniMod N-linked glycosylation, dHex HexNAc" [OMSSA:183, PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:142]
synonym	"dHexHexNAcN" EXACT OMSSA-label []
synonym	"HexNAc(1)dHex(1)" RELATED PSI-MS-label []
synonym	"HexNAc1dHex1" RELATED UniMod-description []
xref	DiffAvg: "349.34"
xref	DiffFormula: "C 14 H 23 N 1 O 9"
xref	DiffMono: "349.137281"
xref	Formula: "C 18 H 29 N 3 O 11"
xref	MassAvg: "463.44"
xref	MassMono: "463.180209"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.511. MOD:00511 HexNAc2

Table 513. Term [MOD:00511]
id	MOD:00511
name	HexNAc2
def	"modification from UniMod N-linked glycosylation, HexNAc(2)" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:143]
synonym	"HexNAc(2)" RELATED PSI-MS-label []
synonym	"HexNAc2" RELATED UniMod-description []
xref	DiffAvg: "406.39"
xref	DiffFormula: "C 16 H 26 N 2 O 10"
xref	DiffMono: "406.158745"
xref	Formula: "C 20 H 32 N 4 O 12"
xref	MassAvg: "520.49"
xref	MassMono: "520.201672"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.512. MOD:00512 Hex3

Table 514. Term [MOD:00512]
id	MOD:00512
name	Hex3
def	"modification from UniMod N-linked glycosylation, Hex3" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:144]
synonym	"Hex(3)" RELATED PSI-MS-label []
synonym	"Hex3" RELATED UniMod-description []
xref	DiffAvg: "486.42"
xref	DiffFormula: "C 18 H 30 O 15"
xref	DiffMono: "486.158470"
xref	Formula: "C 22 H 36 N 2 O 17"
xref	MassAvg: "600.53"
xref	MassMono: "600.201398"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.513. MOD:00513 HexNAc1dHex2

Table 515. Term [MOD:00513]
id	MOD:00513
name	HexNAc1dHex2
def	"modification from UniMod N-linked glycosylation, dHex(2) HexNAc" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:145]
synonym	"HexNAc(1)dHex(2)" RELATED PSI-MS-label []
synonym	"HexNAc1dHex2" RELATED UniMod-description []
xref	DiffAvg: "495.48"
xref	DiffFormula: "C 20 H 33 N 1 O 13"
xref	DiffMono: "495.195190"
xref	Formula: "C 24 H 39 N 3 O 15"
xref	MassAvg: "609.58"
xref	MassMono: "609.238118"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.514. MOD:00514 Hex1HexNAc1dHex1

Table 516. Term [MOD:00514]
id	MOD:00514
name	Hex1HexNAc1dHex1
def	"modification from UniMod N-linked glycosylation, dHex Hex HexNAc" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:146]
synonym	"Hex(1)HexNAc(1)dHex(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1dHex1" RELATED UniMod-description []
xref	DiffAvg: "511.48"
xref	DiffFormula: "C 20 H 33 N 1 O 14"
xref	DiffMono: "511.190105"
xref	Formula: "C 24 H 39 N 3 O 16"
xref	MassAvg: "625.58"
xref	MassMono: "625.233032"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.515. MOD:00515 HexNAc2dHex1

Table 517. Term [MOD:00515]
id	MOD:00515
name	HexNAc2dHex1
def	"modification from UniMod N-linked glycosylation, dHex HexNAc(2)" [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var, UniMod:147]
synonym	"HexNAc(2)dHex(1)" RELATED PSI-MS-label []
synonym	"HexNAc2dHex1" RELATED UniMod-description []
xref	DiffAvg: "552.53"
xref	DiffFormula: "C 22 H 36 N 2 O 14"
xref	DiffMono: "552.216654"
xref	Formula: "C 26 H 42 N 4 O 16"
xref	MassAvg: "666.63"
xref	MassMono: "666.259581"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.516. MOD:00516 Hex1HexNAc2

Table 518. Term [MOD:00516]
id	MOD:00516
name	Hex1HexNAc2
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:148]
synonym	"Hex(1)HexNAc(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc2" RELATED UniMod-description []
xref	DiffAvg: "568.53"
xref	DiffFormula: "C 22 H 36 N 2 O 15"
xref	DiffMono: "568.211568"
xref	Formula: "C 26 H 42 N 4 O 17"
xref	MassAvg: "682.63"
xref	MassMono: "682.254496"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.517. MOD:00517 Hex1HexNAc1NeuAc1 glycosylated residue

Table 519. Term [MOD:00517]
id	MOD:00517
name	Hex1HexNAc1NeuAc1 glycosylated residue
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a carbohydrate-like group composed of Hex1HexNAc1NeuAc1 linked through a glycosidic bond." [DeltaMass:0, UniMod:149]
comment	From DeltaMass: Average Mass: 657
synonym	"Hex(1)HexNAc(1)NeuAc(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc1" RELATED UniMod-description []
synonym	"NeuAc-Hex-HexNAc" EXACT DeltaMass-label []
xref	DiffAvg: "657.60"
xref	DiffFormula: "C 25 H 41 N 2 O 18"
xref	DiffMono: "657.235437"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.518. MOD:00518 HexNAc2dHex2

Table 520. Term [MOD:00518]
id	MOD:00518
name	HexNAc2dHex2
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:150]
synonym	"HexNAc(2)dHex(2)" RELATED PSI-MS-label []
synonym	"HexNAc2dHex2" RELATED UniMod-description []
xref	DiffAvg: "698.67"
xref	DiffFormula: "C 28 H 46 N 2 O 18"
xref	DiffMono: "698.274563"
xref	Formula: "C 32 H 52 N 4 O 20"
xref	MassAvg: "812.78"
xref	MassMono: "812.317490"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.519. MOD:00519 Hex1HexNAc2Pent1

Table 521. Term [MOD:00519]
id	MOD:00519
name	Hex1HexNAc2Pent1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:151]
synonym	"Hex(1)HexNAc(2)Pent(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc2Pent1" RELATED UniMod-description []
xref	DiffAvg: "700.64"
xref	DiffFormula: "C 27 H 44 N 2 O 19"
xref	DiffMono: "700.253827"
xref	Formula: "C 31 H 50 N 4 O 21"
xref	MassAvg: "814.75"
xref	MassMono: "814.296755"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.520. MOD:00520 Hex1HexNAc2dHex1

Table 522. Term [MOD:00520]
id	MOD:00520
name	Hex1HexNAc2dHex1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:152]
synonym	"Hex(1)HexNAc(2)dHex(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc2dHex1" RELATED UniMod-description []
xref	DiffAvg: "714.67"
xref	DiffFormula: "C 28 H 46 N 2 O 19"
xref	DiffMono: "714.269477"
xref	Formula: "C 32 H 52 N 4 O 21"
xref	MassAvg: "828.77"
xref	MassMono: "828.312405"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.521. MOD:00521 Hex2HexNAc2

Table 523. Term [MOD:00521]
id	MOD:00521
name	Hex2HexNAc2
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:153]
synonym	"Hex(2)HexNAc(2)" RELATED PSI-MS-label []
synonym	"Hex2HexNAc2" RELATED UniMod-description []
xref	DiffAvg: "730.67"
xref	DiffFormula: "C 28 H 46 N 2 O 20"
xref	DiffMono: "730.264392"
xref	Formula: "C 32 H 52 N 4 O 22"
xref	MassAvg: "844.77"
xref	MassMono: "844.307319"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.522. MOD:00522 Hex3HexNAc1Pent1

Table 524. Term [MOD:00522]
id	MOD:00522
name	Hex3HexNAc1Pent1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:154]
synonym	"Hex(3)HexNAc(1)Pent(1)" RELATED PSI-MS-label []
synonym	"Hex3HexNAc1Pent1" RELATED UniMod-description []
xref	DiffAvg: "821.73"
xref	DiffFormula: "C 31 H 51 N 1 O 24"
xref	DiffMono: "821.280102"
xref	Formula: "C 35 H 57 N 3 O 26"
xref	MassAvg: "935.84"
xref	MassMono: "935.323029"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.523. MOD:00523 Hex1HexNAc2dHex1Pent1

Table 525. Term [MOD:00523]
id	MOD:00523
name	Hex1HexNAc2dHex1Pent1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:155]
synonym	"Hex(1)HexNAc(2)dHex(1)Pent(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc2dHex1Pent1" RELATED UniMod-description []
xref	DiffAvg: "846.79"
xref	DiffFormula: "C 33 H 54 N 2 O 23"
xref	DiffMono: "846.311736"
xref	Formula: "C 35 H 57 N 3 O 26"
xref	MassAvg: "935.84"
xref	MassMono: "935.323029"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.524. MOD:00524 Hex1HexNAc2dHex2

Table 526. Term [MOD:00524]
id	MOD:00524
name	Hex1HexNAc2dHex2
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:156]
synonym	"Hex(1)HexNAc(2)dHex(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc2dHex2" RELATED UniMod-description []
xref	DiffAvg: "860.81"
xref	DiffFormula: "C 34 H 56 N 2 O 23"
xref	DiffMono: "860.327386"
xref	Formula: "C 38 H 62 N 4 O 25"
xref	MassAvg: "974.92"
xref	MassMono: "974.370313"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.525. MOD:00525 Hex2HexNAc2Pent1

Table 527. Term [MOD:00525]
id	MOD:00525
name	Hex2HexNAc2Pent1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:157]
synonym	"Hex(2)HexNAc(2)Pent(1)" RELATED PSI-MS-label []
synonym	"Hex2HexNAc2Pent1" RELATED UniMod-description []
xref	DiffAvg: "862.79"
xref	DiffFormula: "C 33 H 54 N 2 O 24"
xref	DiffMono: "862.306651"
xref	Formula: "C 37 H 60 N 4 O 26"
xref	MassAvg: "976.89"
xref	MassMono: "976.349578"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.526. MOD:00526 Hex2HexNAc2dHex1

Table 528. Term [MOD:00526]
id	MOD:00526
name	Hex2HexNAc2dHex1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:158]
synonym	"Hex(2)HexNAc(2)dHex(1)" RELATED PSI-MS-label []
synonym	"Hex2HexNAc2dHex1" RELATED UniMod-description []
xref	DiffAvg: "876.81"
xref	DiffFormula: "C 34 H 56 N 2 O 24"
xref	DiffMono: "876.322301"
xref	Formula: "C 38 H 62 N 4 O 26"
xref	MassAvg: "990.92"
xref	MassMono: "990.365228"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.527. MOD:00527 Hex3HexNAc2

Table 529. Term [MOD:00527]
id	MOD:00527
name	Hex3HexNAc2
def	"modification from UniMod N-linked glycosylation" [DeltaMass:0, RESID:AA0151#var, UniMod:159]
comment	From DeltaMass: Average Mass: 893
synonym	"(Hex)3-HexNAc-HexNAc" EXACT DeltaMass-label []
synonym	"Hex(3)HexNAc(2)" RELATED PSI-MS-label []
synonym	"Hex3HexNAc2" RELATED UniMod-description []
xref	DiffAvg: "892.81"
xref	DiffFormula: "C 34 H 56 N 2 O 25"
xref	DiffMono: "892.317215"
xref	Formula: "C 38 H 62 N 4 O 27"
xref	MassAvg: "1006.92"
xref	MassMono: "1006.360143"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.528. MOD:00528 Hex1HexNAc1NeuAc2 glycosylated residue

Table 530. Term [MOD:00528]
id	MOD:00528
name	Hex1HexNAc1NeuAc2 glycosylated residue
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a carbohydrate-like group composed of Hex1HexNAc1NeuAc2 linked through a glycosidic bond." [UniMod:160]
synonym	"Hex(1)HexNAc(1)NeuAc(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc2" RELATED UniMod-description []
xref	DiffAvg: "947.85"
xref	DiffFormula: "C 36 H 57 N 3 O 26"
xref	DiffMono: "947.323029"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.529. MOD:00529 Hex3HexNAc2P1

Table 531. Term [MOD:00529]
id	MOD:00529
name	Hex3HexNAc2P1
def	"modification from UniMod N-linked glycosylation" [RESID:AA0151#var, UniMod:161]
synonym	"Hex(3)HexNAc(2)P(1)" RELATED PSI-MS-label []
synonym	"Hex3HexNAc2P1" RELATED UniMod-description []
xref	DiffAvg: "972.79"
xref	DiffFormula: "C 34 H 57 N 2 O 28 P 1"
xref	DiffMono: "972.283546"
xref	Formula: "C 38 H 63 N 4 O 30 P 1"
xref	MassAvg: "1086.89"
xref	MassMono: "1086.326473"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.530. MOD:00530 L-selenomethionine

Table 532. Term [MOD:00530]
id	MOD:00530
name	L-selenomethionine
def	"A protein modification that effectively converts an L-methionine residue to L-selenomethionine." [OMSSA:113, PubMed:12148805, UniMod:162#M]
synonym	"Delta:S(-1)Se(1)" RELATED PSI-MS-label []
synonym	"Se(S)Met" EXACT PSI-MOD-label []
synonym	"Selenium replaces sulphur" RELATED UniMod-description []
synonym	"semetm" EXACT OMSSA-label []
xref	DiffAvg: "46.91"
xref	DiffFormula: "C 0 H 0 N 0 S -1 Se 1"
xref	DiffMono: "47.944450"
xref	Formula: "C 5 H 9 N 1 O 1 Se 1"
xref	MassAvg: "178.10"
xref	MassMono: "178.984935"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00007 selenium substitution for sulfur ! selenium substitution for sulfur
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.531. MOD:00531 (18)O labeled deglycosylated asparagine

Table 533. Term [MOD:00531]
id	MOD:00531
name	(18)O labeled deglycosylated asparagine
def	"A protein modification that effectively converts an L-asparagine residue to L-aspartic acid with one (18)O as the result of having been deglycosylated in (18)O water." [PubMed:14435542, UniMod:170]
subset	PSI-MOD-slim
synonym	"Delta:H(1)O(-1)18O(1)" RELATED PSI-MS-label []
synonym	"glycosylated asparagine 18O labeling" RELATED UniMod-description []
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "C 4 H 5 N 1 (16)O 2 (18)O 1"
xref	MassAvg: "117.03"
xref	MassMono: "117.031189"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01293 1x(18)O labeled deamidated L-asparagine ! 1x(18)O labeled deamidated L-asparagine

2.532. MOD:00532 Shimadzu 13CNBS

Table 534. Term [MOD:00532]
id	MOD:00532
name	Shimadzu 13CNBS
def	"modification from UniMod Chemical derivative" [PubMed:12845591, UniMod:171]
synonym	"NBS:13C(6)" RELATED UniMod-interim []
synonym	"Shimadzu NBS-13C" RELATED UniMod-description []
xref	DiffAvg: "159.01"
xref	DiffFormula: "(13)C 6 H 3 N 1 O 2 S 1"
xref	DiffMono: "159.008578"
xref	Formula: "(12)C 11 (13)C 6 H 13 N 3 O 3 S 1"
xref	MassAvg: "345.09"
xref	MassMono: "345.087891"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.533. MOD:00533 Shimadzu 12CNBS

Table 535. Term [MOD:00533]
id	MOD:00533
name	Shimadzu 12CNBS
def	"modification from UniMod Chemical derivative" [PubMed:12845591, UniMod:172]
synonym	"NBS" RELATED UniMod-interim []
synonym	"Shimadzu NBS-12C" RELATED UniMod-description []
xref	DiffAvg: "152.99"
xref	DiffFormula: "(12)C 6 H 3 N 1 O 2 S 1"
xref	DiffMono: "152.988449"
xref	Formula: "(12)C 17 H 13 N 3 O 3 S 1"
xref	MassAvg: "339.07"
xref	MassMono: "339.067762"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.534. MOD:00534 Michael addition of BHT quinone methide to cysteine and lysine

Table 536. Term [MOD:00534]
id	MOD:00534
name	Michael addition of BHT quinone methide to cysteine and lysine
def	"modification from UniMod Post-translational" [PubMed:9448752, UniMod:176]
comment	Butylated Hydroxytoluene adduct.
synonym	"BHT" RELATED PSI-MS-label []
synonym	"Michael addition of BHT quinone methide to Cysteine and Lysine" RELATED UniMod-description []
xref	DiffAvg: "218.34"
xref	DiffFormula: "C 15 H 22 O 1"
xref	DiffMono: "218.167065"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.535. MOD:00535 phosphorylation to amine thiol

Table 537. Term [MOD:00535]
id	MOD:00535
name	phosphorylation to amine thiol
def	"modification from UniMod Chemical derivative" [PubMed:12216740, UniMod:178]
comment	DAET = 2-(dimethylamino)ethanethiol. The phosphorylation to amine is the beta elimination of phosphate and Michael addition of 2-(dimethylamino)ethanethiol to the site.
synonym	"DAET" RELATED PSI-MS-label []
synonym	"phosphorylation to amine thiol" RELATED UniMod-description []
xref	DiffAvg: "87.18"
xref	DiffFormula: "C 4 H 9 N 1 O -1 S 1"
xref	DiffMono: "87.050656"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.536. MOD:00536 L-serine to L-alanine replacement

Table 538. Term [MOD:00536]
id	MOD:00536
name	L-serine to L-alanine replacement
def	"OBSOLETE because UniMod 179 merged wth UniMod 447 remap to ??? a protein modification that replaces an L-serine residue with an L-alanine residue" [UniMod:179]
synonym	"Ser_Ala" EXACT PSI-MOD-label []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "O -1"
xref	DiffMono: "-15.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.537. MOD:00537 L-alanine residue (Thr)

Table 539. Term [MOD:00537]
id	MOD:00537
name	L-alanine residue (Thr)
def	"A protein modification that effectively converts an L-threonine residue to L-alanine." [UniMod:659]
comment	This could represent either an engineered replacement or a chemical modification.
synonym	"Thr(Ala)" EXACT PSI-MOD-label []
synonym	"Thr→Ala" RELATED UniMod-interim []
synonym	"Thr→Ala substitution" RELATED UniMod-description []
xref	DiffAvg: "-30.03"
xref	DiffFormula: "C -1 H -2 O -1"
xref	DiffMono: "-30.010565"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "T"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00010 L-alanine residue ! L-alanine residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.538. MOD:00538 protein modification categorized by isobaric sets

Table 540. Term [MOD:00538]
id	MOD:00538
name	protein modification categorized by isobaric sets
def	"Modified amino acid residues groups into isobaric sets at particular mass resolution cut-offs." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	[MOD:00000] ! protein modification

2.539. MOD:00539 threonine reduced to aminobutynate

Table 541. Term [MOD:00539]
id	MOD:00539
name	threonine reduced to aminobutynate
def	"OBSOLETE because UniMod 179 merged wth UniMod 447 remap to ??? modification from UniMod O-linked glycosylation" [UniMod:182]
xref	DiffAvg: "-17.01"
xref	DiffFormula: "H -1 O -1"
xref	DiffMono: "-17.002740"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.540. MOD:00540 9x(13)C labeled residue

Table 542. Term [MOD:00540]
id	MOD:00540
name	9x(13)C labeled residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 9x(13)C labeled residue." [PubMed:12716131, UniMod:184]
synonym	"13C(9) Silac label" RELATED UniMod-description []
synonym	"Label:13C(9)" RELATED PSI-MS-label []
xref	DiffAvg: "9.03"
xref	DiffFormula: "(12)C -9 (13)C 9"
xref	DiffMono: "9.030194"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue

2.541. MOD:00541 9x(13)C labeled L-phosphotyrosine

Table 543. Term [MOD:00541]
id	MOD:00541
name	9x(13)C labeled L-phosphotyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 9x(13)C labeled L-phosphotyrosine." [PubMed:12716131, UniMod:185]
synonym	"C13 label (Phosphotyrosine)" RELATED UniMod-description []
synonym	"Label:13C(9)+Phospho" RELATED PSI-MS-label []
xref	DiffAvg: "89.00"
xref	DiffFormula: "(12)C -9 (13)C 9 H 1 O 3 P 1"
xref	DiffMono: "88.996524"
xref	Formula: "(13)C 9 H 10 N 1 O 5 P 1"
xref	MassAvg: "252.06"
xref	MassMono: "252.059853"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00540 9x(13)C labeled residue ! 9x(13)C labeled residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
relationship	derives_from MOD:00048 O4'-phospho-L-tyrosine ! O4'-phospho-L-tyrosine

2.542. MOD:00542 hydroxyphenylglyoxal arginine

Table 544. Term [MOD:00542]
id	MOD:00542
name	hydroxyphenylglyoxal arginine
def	"modification from UniMod Chemical derivative" [PubMed:11698400, PubMed:11914093, UniMod:186]
synonym	"HPG" RELATED PSI-MS-label []
synonym	"Hydroxyphenylglyoxal arginine" RELATED UniMod-description []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 8 H 4 O 2"
xref	DiffMono: "132.021129"
xref	Formula: "C 14 H 16 N 4 O 3"
xref	MassAvg: "288.31"
xref	MassMono: "288.122240"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.543. MOD:00543 bis(hydroxyphenylglyoxal) arginine

Table 545. Term [MOD:00543]
id	MOD:00543
name	bis(hydroxyphenylglyoxal) arginine
def	"modification from UniMod Chemical derivative" [PubMed:11698400, UniMod:187]
comment	OH-PGO and PGO react with arginine at a stoichiometry of 2:1 [UniMod].
synonym	"2HPG" RELATED PSI-MS-label []
synonym	"bis(hydroxphenylglyoxal) arginine" RELATED UniMod-description []
xref	DiffAvg: "282.25"
xref	DiffFormula: "C 16 H 10 O 5"
xref	DiffMono: "282.052823"
xref	Formula: "C 22 H 22 N 4 O 6"
xref	MassAvg: "438.44"
xref	MassMono: "438.153934"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.544. MOD:00544 6x(13)C labeled residue

Table 546. Term [MOD:00544]
id	MOD:00544
name	6x(13)C labeled residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 6x(13)C labeled residue." [PubMed:12716131, UniMod:188]
subset	PSI-MOD-slim
synonym	"13C(6) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "6.02"
xref	DiffFormula: "(12)C -6 (13)C 6"
xref	DiffMono: "6.020129"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue

2.545. MOD:00545 deuterated dimethyl labeling (D)

Table 547. Term [MOD:00545]
id	MOD:00545
name	deuterated dimethyl labeling (D)
def	"OBSOLETE because redundant with MOD:00927. Remap to MOD:00927." [PubMed:14670044]
xref	DiffAvg: "34.07"
xref	DiffFormula: "C 2 (1)H -2 (2)H 6"
xref	DiffMono: "34.068961"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_obsolete	true

2.546. MOD:00546 (18)O label at both C-terminal oxygens

Table 548. Term [MOD:00546]
id	MOD:00546
name	(18)O label at both C-terminal oxygens
def	"A protein modification that effectively substitutes two (18)O atom for the two (16)O atoms of an alpha-carboxyl (1-carboxyl) group." [OMSSA:88, PubMed:11467524, UniMod:193]
subset	PSI-MOD-slim
synonym	"ctermpepdio18" EXACT OMSSA-label []
synonym	"Label:18O(2)" RELATED PSI-MS-label []
synonym	"O18 label at both C-terminal oxygens" RELATED UniMod-description []
xref	DiffAvg: "4.01"
xref	DiffFormula: "(16)O -2 (18)O 2"
xref	DiffMono: "4.008493"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00847 (18)O disubstituted residue ! (18)O disubstituted residue

2.547. MOD:00547 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate

Table 549. Term [MOD:00547]
id	MOD:00547
name	6-aminoquinolyl-N-hydroxysuccinimidyl carbamate
def	"modification from UniMod Chemical derivative" [PubMed:14997490, UniMod:194]
synonym	"6-aminoquinolyl-N-hydroxysuccinimidyl carbamate" RELATED UniMod-description []
synonym	"AccQTag" RELATED PSI-MS-label []
xref	DiffAvg: "170.17"
xref	DiffFormula: "C 10 H 6 N 2 O 1"
xref	DiffMono: "170.048013"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.548. MOD:00548 APTA-d0

Table 550. Term [MOD:00548]
id	MOD:00548
name	APTA-d0
def	"modification from UniMod Chemical derivative" [PubMed:15283597, UniMod:195]
comment	Derivatization of cysteine with 3-acrylamidopropyl)trimethylammonium chloride [JSG].
synonym	"APTA-d0" RELATED UniMod-description []
synonym	"QAT" RELATED PSI-MS-label []
xref	DiffAvg: "171.26"
xref	DiffFormula: "C 9 H 19 N 2 O 1"
xref	DiffMono: "171.149738"
xref	Formula: "C 12 H 24 N 3 O 2 S 1"
xref	MassAvg: "274.40"
xref	MassMono: "274.158923"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.549. MOD:00549 APTA d3

Table 551. Term [MOD:00549]
id	MOD:00549
name	APTA d3
def	"modification from UniMod Isotopic label" [PubMed:15283597, UniMod:196]
comment	Derivatization of cysteine with 3-acrylamidopropyl)trimethylammonium chloride (difference formula correct) [JSG].
synonym	"(3-acrylamidopropyl)trimethylammonium" RELATED UniMod-description []
synonym	"APTA d3" RELATED UniMod-description []
synonym	"QAT:2H(3)" RELATED PSI-MS-label []
xref	DiffAvg: "174.17"
xref	DiffFormula: "C 9 (1)H 16 (2)H 3 N 2 O 1"
xref	DiffMono: "174.168568"
xref	Formula: "C 12 (1)H 21 (2)H 3 N 3 O 2 S 1"
xref	MassAvg: "277.18"
xref	MassMono: "277.177753"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.550. MOD:00550 EAPTA d0

Table 552. Term [MOD:00550]
id	MOD:00550
name	EAPTA d0
def	"modification from UniMod Chemical derivative" [UniMod:197]
synonym	"EAPTA d0" RELATED UniMod-description []
synonym	"EQAT" RELATED PSI-MS-label []
xref	DiffAvg: "184.28"
xref	DiffFormula: "C 10 H 20 N 2 O 1"
xref	DiffMono: "184.157563"
xref	Formula: "C 13 H 25 N 3 O 2 S 1"
xref	MassAvg: "287.42"
xref	MassMono: "287.166748"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.551. MOD:00551 EAPTA d5

Table 553. Term [MOD:00551]
id	MOD:00551
name	EAPTA d5
def	"modification from UniMod Isotopic label" [UniMod:198]
synonym	"EAPTA d5" RELATED UniMod-description []
synonym	"EQAT:2H(5)" RELATED PSI-MS-label []
xref	DiffAvg: "189.19"
xref	DiffFormula: "C 10 (1)H 15 (2)H 5 N 2 O 1"
xref	DiffMono: "189.188947"
xref	Formula: "C 13 (1)H 20 (2)H 5 N 3 O 2 S 1"
xref	MassAvg: "292.20"
xref	MassMono: "292.198132"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.552. MOD:00552 4x(2)H labeled dimethylated residue

Table 554. Term [MOD:00552]
id	MOD:00552
name	4x(2)H labeled dimethylated residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 4x(2)H labeled dimethylated residue." [PubMed:14670044, UniMod:199]
comment	Supposed to be alpha-amino and Lys-N6 derivatized by C(2)H2O and reduction.
subset	PSI-MOD-slim
synonym	"DiMethyl-CHD2" RELATED UniMod-description []
synonym	"Dimethyl:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 2 (2)H 4"
xref	DiffMono: "32.056407"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue

2.553. MOD:00553 1,2-ethanedithiol modified residue

Table 555. Term [MOD:00553]
id	MOD:00553
name	1,2-ethanedithiol modified residue
def	"A protein modification that effectively substitutes a (2-sulfanylethyl)sulfanyl (or thioethylthiol) group for a hydroxy group." [DeltaMass:0, PubMed:11507762, UniMod:200]
comment	From DeltaMass: Average Mass: 93; supposed to be derivatization of serine and threonine.
synonym	"1,2-ethanedithiol (EDT)" EXACT DeltaMass-label []
synonym	"EDT" RELATED UniMod-description []
synonym	"Ethanedithiol" RELATED PSI-MS-label []
xref	DiffAvg: "76.18"
xref	DiffFormula: "C 2 H 4 O -1 S 2"
xref	DiffMono: "75.980528"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.554. MOD:00554 APTA-d0 with no neutral loss

Table 556. Term [MOD:00554]
id	MOD:00554
name	APTA-d0 with no neutral loss
def	"OBSOLETE because UniMod entry 202 was merged with entry 195, remap to MOD:00548. modification from UniMod Chemical derivative" [UniMod:202]
xref	DiffAvg: "170.26"
xref	DiffFormula: "C 9 H 18 N 2 O 1"
xref	DiffMono: "170.141913"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.555. MOD:00555 APTA-d0 with quaternary amine loss

Table 557. Term [MOD:00555]
id	MOD:00555
name	APTA-d0 with quaternary amine loss
def	"OBSOLETE because UniMod entry 202 was merged with entry 195, remap to MOD:00548. modification from UniMod Chemical derivative" [UniMod:203]
xref	DiffAvg: "170.26"
xref	DiffFormula: "C 9 H 18 N 2 O 1"
xref	DiffMono: "170.141913"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.556. MOD:00556 acrolein addition +94

Table 558. Term [MOD:00556]
id	MOD:00556
name	acrolein addition +94
def	"modification from UniMod Other" [UniMod:205]
synonym	"Acrolein addition +94" RELATED UniMod-description []
synonym	"Delta:H(6)C(6)O(1)" RELATED PSI-MS-label []
xref	DiffAvg: "94.11"
xref	DiffFormula: "C 6 H 6 O 1"
xref	DiffMono: "94.041865"
xref	Formula: "C 12 H 18 N 2 O 2"
xref	MassAvg: "222.29"
xref	MassMono: "222.136828"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.557. MOD:00557 acrolein addition +56

Table 559. Term [MOD:00557]
id	MOD:00557
name	acrolein addition +56
def	"modification from UniMod Other" [PubMed:10825247, PubMed:15541752, UniMod:206]
synonym	"Acrolein addition +56" RELATED UniMod-description []
synonym	"Delta:H(4)C(3)O(1)" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.558. MOD:00558 acrolein addition +38

Table 560. Term [MOD:00558]
id	MOD:00558
name	acrolein addition +38
def	"modification from UniMod Other" [UniMod:207]
synonym	"Acrolein addition +38" RELATED UniMod-description []
synonym	"Delta:H(2)C(3)" RELATED PSI-MS-label []
xref	DiffAvg: "38.05"
xref	DiffFormula: "C 3 H 2"
xref	DiffMono: "38.015650"
xref	Formula: "C 9 H 14 N 2 O 1"
xref	MassAvg: "166.22"
xref	MassMono: "166.110613"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.559. MOD:00559 acrolein addition +76

Table 561. Term [MOD:00559]
id	MOD:00559
name	acrolein addition +76
def	"modification from UniMod Other" [UniMod:208]
synonym	"Acrolein addition +76" RELATED UniMod-description []
synonym	"Delta:H(4)C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "76.10"
xref	DiffFormula: "C 6 H 4"
xref	DiffMono: "76.031300"
xref	Formula: "C 12 H 16 N 2 O 1"
xref	MassAvg: "204.27"
xref	MassMono: "204.126263"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.560. MOD:00560 acrolein addition +112

Table 562. Term [MOD:00560]
id	MOD:00560
name	acrolein addition +112
def	"modification from UniMod Other" [UniMod:209]
synonym	"Acrolein addition +112" RELATED UniMod-description []
synonym	"Delta:H(8)C(6)O(2)" RELATED PSI-MS-label []
xref	DiffAvg: "112.13"
xref	DiffFormula: "C 6 H 8 O 2"
xref	DiffMono: "112.052429"
xref	Formula: "C 12 H 20 N 2 O 3"
xref	MassAvg: "240.30"
xref	MassMono: "240.147393"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.561. MOD:00561 N-ethyl iodoacetamide-d0

Table 563. Term [MOD:00561]
id	MOD:00561
name	N-ethyl iodoacetamide-d0
def	"modification from UniMod Isotopic label" [PubMed:12766232, UniMod:211]
synonym	"N-ethyl iodoacetamide-d0" RELATED UniMod-description []
synonym	"NEIAA" RELATED PSI-MS-label []
xref	DiffAvg: "85.11"
xref	DiffFormula: "C 4 H 7 N 1 O 1"
xref	DiffMono: "85.052764"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.562. MOD:00562 N-ethyl iodoacetamide-d5

Table 564. Term [MOD:00562]
id	MOD:00562
name	N-ethyl iodoacetamide-d5
def	"modification from UniMod Isotopic label" [PubMed:12766232, UniMod:212]
synonym	"N-ethyl iodoacetamide-d5" RELATED UniMod-description []
synonym	"NEIAA:2H(5)" RELATED PSI-MS-label []
xref	DiffAvg: "90.08"
xref	DiffFormula: "C 4 (1)H 2 (2)H 5 N 1 O 1"
xref	DiffMono: "90.084148"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.563. MOD:00563 N-acetylaminogalactosylated residue

Table 565. Term [MOD:00563]
id	MOD:00563
name	N-acetylaminogalactosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an N-acetylaminogalactose group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"GalNAcRes" EXACT PSI-MOD-label []
synonym	"HexNAc" RELATED PSI-MS-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00734 N-acetylaminogalactosylated ! N-acetylaminogalactosylated
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.564. MOD:00564 Applied Biosystems iTRAQ™ multiplexed quantitation chemistry

Table 566. Term [MOD:00564]
id	MOD:00564
name	Applied Biosystems iTRAQ™ multiplexed quantitation chemistry
def	"Modification from UniMod Isotopic label. The UniMod term was extracted when it had not been approved. OBSOLETE because redundant to MOD:01505. Remap to MOD:01505, or one of the child terms MOD:01493 or MOD:01497." [UniMod:214, URL:http\://docs.appliedbiosystems.com/pebiodocs/04351918.pdf]
synonym	"iTRAQ4plex" RELATED UniMod-interim []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 O 1"
xref	DiffMono: "144.102062"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.565. MOD:00565 deglycosylated asparagine

Table 567. Term [MOD:00565]
id	MOD:00565
name	deglycosylated asparagine
def	"modification from UniMod N-linked glycosylation" [UniMod:7#N]
comment	Conversion of glycosylated asparagine residues upon deglycosylation with PGNase F in H2O. CAUTION - the difference formula appears to be based on a partial structure [JSG].
synonym	"Deamidated" RELATED UniMod-interim []
synonym	"Deamidation" RELATED UniMod-description []
xref	DiffAvg: "0.98"
xref	DiffFormula: "H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.566. MOD:00566 label cysteine with IGBP reagent

Table 568. Term [MOD:00566]
id	MOD:00566
name	label cysteine with IGBP reagent
def	"modification from UniMod Chemical derivative" [UniMod:243]
comment	"IDBEST tag for quantitation, http://www.targetdiscovery.com/index.php?topic=prod.idbe"
synonym	"IGBP" RELATED PSI-MS-label []
synonym	"Light IDBEST tag for quantitation" RELATED UniMod-description []
xref	DiffAvg: "297.15"
xref	DiffFormula: "Br 1 C 12 H 13 N 2 O 2"
xref	DiffMono: "296.016040"
xref	Formula: "Br 1 C 15 H 18 N 3 O 3 S 1"
xref	MassAvg: "400.29"
xref	MassMono: "399.025225"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.567. MOD:00567 histidine oxidation to asparagine

Table 569. Term [MOD:00567]
id	MOD:00567
name	histidine oxidation to asparagine
def	"OBSOLETE because UniMod entry 244 is redundant with UniMod 348. Remap to MOD:00775." [ChEBI:29956, PubMed:15736973, PubMed:5681232, PubMed:6692818, PubMed:9789001, RESID:AA0003, UniMod:244]
xref	DiffAvg: "-23.04"
xref	DiffFormula: "C -2 H -1 N -1 O 1"
xref	DiffMono: "-23.015984"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.568. MOD:00568 histidine oxidation to aspartic acid

Table 570. Term [MOD:00568]
id	MOD:00568
name	histidine oxidation to aspartic acid
def	"OBSOLETE because UniMod entry 245 is redundant with UniMod 349. Remap to MOD:00776" [PubMed:1097438, PubMed:339692, PubMed:4399050, PubMed:5764436, PubMed:6692818, PubMed:8089117, PubMed:9521123, PubMed:9582379, UniMod:245]
xref	DiffAvg: "-22.05"
xref	DiffFormula: "C -2 H -2 N -2 O 2"
xref	DiffMono: "-22.031969"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.569. MOD:00569 residues isobaric at a resolution below 0.000001 Da

Table 571. Term [MOD:00569]
id	MOD:00569
name	residues isobaric at a resolution below 0.000001 Da
def	"Natural or modified residues that are isobaric at a resolution below 0.000001 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00770 residues isobaric at a resolution below 0.01 Da ! residues isobaric at a resolution below 0.01 Da

2.570. MOD:00570 residues isobaric at 71.037114 Da

Table 572. Term [MOD:00570]
id	MOD:00570
name	residues isobaric at 71.037114 Da
def	"Natural or modified residues with a mass of 71.037114 Da." [PubMed:18688235]
is_a	MOD:00569 residues isobaric at a resolution below 0.000001 Da ! residues isobaric at a resolution below 0.000001 Da
is_a	MOD:00769 residues isobaric at 71.0-71.1 Da ! residues isobaric at 71.0-71.1 Da

2.571. MOD:00571 2-pyrrolidone-5-carboxylic acid (Pro)

Table 573. Term [MOD:00571]
id	MOD:00571
name	2-pyrrolidone-5-carboxylic acid (Pro)
def	"A modification that effectively oxygenates C5 of an L-proline residue to form a 2-pyrrolidone-5-carboxylic acid, pyroglutamic acid." [OMSSA:111, PubMed:9252331, UniMod:359]
comment	The review article PubMed:9252331 does not provide an original citation for this modification [JSG].
synonym	"Pro→pyro-Glu" RELATED PSI-MS-label []
synonym	"PyrGlu(Pro)" EXACT PSI-MOD-label []
synonym	"Pyroglutamic" RELATED UniMod-interim []
synonym	"pyroglutamicp" EXACT OMSSA-label []
xref	DiffAvg: "13.98"
xref	DiffFormula: "H -2 O 1"
xref	DiffMono: "13.979265"
xref	Formula: "C 5 H 6 N 1 O 2"
xref	MassAvg: "112.11"
xref	MassMono: "112.039853"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01048 2-pyrrolidone-5-carboxylic acid ! 2-pyrrolidone-5-carboxylic acid

2.572. MOD:00572 oxidized arginine biotinylated with biotin hydrazide

Table 574. Term [MOD:00572]
id	MOD:00572
name	oxidized arginine biotinylated with biotin hydrazide
def	"modification from UniMod Chemical derivative" [PubMed:15174056, PubMed:15828771, UniMod:343]
synonym	"Argbiotinhydrazide" RELATED UniMod-interim []
synonym	"oxidized Arginine biotinylated with biotin hydrazide" RELATED UniMod-description []
xref	DiffAvg: "199.27"
xref	DiffFormula: "C 9 H 13 N 1 O 2 S 1"
xref	DiffMono: "199.066700"
xref	Formula: "C 15 H 25 N 5 O 3 S 1"
xref	MassAvg: "355.46"
xref	MassMono: "355.167811"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.573. MOD:00573 oxidized lysine biotinylated with biotin hydrazide

Table 575. Term [MOD:00573]
id	MOD:00573
name	oxidized lysine biotinylated with biotin hydrazide
def	"modification from UniMod Chemical derivative" [PubMed:15174056, UniMod:353]
comment	"http://www.piercenet.com/Proteomics/browse.cfm?fldID=84EBE112-F871-4CA5-807F-47327153CFCB"
synonym	"Lysbiotinhydrazide" RELATED UniMod-interim []
synonym	"oxidized Lysine biotinylated with biotin hydrazide" RELATED UniMod-description []
xref	DiffAvg: "241.31"
xref	DiffFormula: "C 10 H 15 N 3 O 2 S 1"
xref	DiffMono: "241.088498"
xref	Formula: "C 16 H 27 N 5 O 3 S 1"
xref	MassAvg: "369.48"
xref	MassMono: "369.183461"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.574. MOD:00574 oxidized proline biotinylated with biotin hydrazide

Table 576. Term [MOD:00574]
id	MOD:00574
name	oxidized proline biotinylated with biotin hydrazide
def	"modification from UniMod Chemical derivative" [PubMed:15174056, UniMod:357]
comment	"http://www.piercenet.com/Proteomics/browse.cfm?fldID=84EBE112-F871-4CA5-807F-47327153CFCB"
synonym	"oxidized proline biotinylated with biotin hydrazide" RELATED UniMod-description []
synonym	"probiotinhydrazide" RELATED UniMod-interim []
xref	DiffAvg: "258.34"
xref	DiffFormula: "C 10 H 18 N 4 O 2 S 1"
xref	DiffMono: "258.115047"
xref	Formula: "C 15 H 25 N 5 O 3 S 1"
xref	MassAvg: "355.46"
xref	MassMono: "355.167811"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.575. MOD:00575 oxidized threonine biotinylated with biotin hydrazide

Table 577. Term [MOD:00575]
id	MOD:00575
name	oxidized threonine biotinylated with biotin hydrazide
def	"modification from UniMod Chemical derivative" [PubMed:15174056, UniMod:361]
comment	"http://www.piercenet.com/Proteomics/browse.cfm?fldID=84EBE112-F871-4CA5-807F-47327153CFCB"
synonym	"oxidized Threonine biotinylated with biotin hydrazide" RELATED UniMod-description []
synonym	"Thrbiotinhydrazide" RELATED UniMod-interim []
xref	DiffAvg: "240.32"
xref	DiffFormula: "C 10 H 16 N 4 O 1 S 1"
xref	DiffMono: "240.104482"
xref	Formula: "C 14 H 23 N 5 O 3 S 1"
xref	MassAvg: "341.43"
xref	MassMono: "341.152161"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.576. MOD:00576 crotonaldehyde

Table 578. Term [MOD:00576]
id	MOD:00576
name	crotonaldehyde
def	"modification from UniMod Other" [PubMed:11283024, UniMod:253]
synonym	"Crotonaldehyde" RELATED PSI-MS-label []
synonym	"Crotonaldehyde" RELATED UniMod-description []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.577. MOD:00577 acetaldehyde +26

Table 579. Term [MOD:00577]
id	MOD:00577
name	acetaldehyde +26
def	"modification from UniMod Other" [PubMed:7744761, UniMod:254]
synonym	"Acetaldehyde +26" RELATED UniMod-description []
synonym	"Delta:H(2)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "26.04"
xref	DiffFormula: "C 2 H 2"
xref	DiffMono: "26.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.578. MOD:00578 acetaldehyde +28

Table 580. Term [MOD:00578]
id	MOD:00578
name	acetaldehyde +28
def	"modification from UniMod Other" [UniMod:255]
synonym	"Acetaldehyde +28" RELATED UniMod-description []
synonym	"Delta:H(4)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.579. MOD:00579 propionaldehyde +40

Table 581. Term [MOD:00579]
id	MOD:00579
name	propionaldehyde +40
def	"modification from UniMod Other" [UniMod:256]
synonym	"Delta:H(4)C(3)" RELATED PSI-MS-label []
synonym	"Propionaldehyde +40" RELATED UniMod-description []
xref	DiffAvg: "40.06"
xref	DiffFormula: "C 3 H 4"
xref	DiffMono: "40.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.580. MOD:00580 propionaldehyde +42

Table 582. Term [MOD:00580]
id	MOD:00580
name	propionaldehyde +42
def	"OBSOLETE because entry removed from UniMod. Remap potentially to MOD:00579 propionaldehyde +40" [UniMod:257]
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6"
xref	DiffMono: "42.046950"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.581. MOD:00581 (18)O monosubstituted residue

Table 583. Term [MOD:00581]
id	MOD:00581
name	(18)O monosubstituted residue
def	"A protein modification that effectively substitutes one (18)O atom for one (16)O atom." [OMSSA:87, PubMed:11467524, UniMod:258]
subset	PSI-MOD-slim
synonym	"ctermpepo18" EXACT OMSSA-label []
synonym	"Label:18O(1)" RELATED PSI-MS-label []
synonym	"O18 Labeling" RELATED UniMod-description []
xref	DiffAvg: "2.00"
xref	DiffFormula: "(16)O -1 (18)O 1"
xref	DiffMono: "2.004246"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00845 (18)O substituted residue ! (18)O substituted residue

2.582. MOD:00582 6x(13)C,2x(15)N labeled L-lysine

Table 584. Term [MOD:00582]
id	MOD:00582
name	6x(13)C,2x(15)N labeled L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 6x(13)C,2x(15)N labeled L-lysine." [OMSSA:181, PubMed:12716131, UniMod:259]
synonym	"13C(6) 15N(2) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)15N(2)" RELATED PSI-MS-label []
synonym	"lys-13C615N2" EXACT OMSSA-label []
xref	DiffAvg: "8.01"
xref	DiffFormula: "(12)C -6 (13)C 6 (14)N -2 (15)N 2"
xref	DiffMono: "8.014199"
xref	Formula: "(13)C 6 H 12 (15)N 2 O 1"
xref	MassAvg: "136.11"
xref	MassMono: "136.109162"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.583. MOD:00583 thiophosphorylated residue

Table 585. Term [MOD:00583]
id	MOD:00583
name	thiophosphorylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a thiophosphono group (H2PO2S, 'thiophosphate')." [PubMed:12110917, UniMod:260]
synonym	"Thiophospho" RELATED PSI-MS-label []
synonym	"Thiophosphorylation" RELATED UniMod-description []
xref	DiffAvg: "96.04"
xref	DiffFormula: "H 1 O 2 P 1 S 1"
xref	DiffMono: "95.943487"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.584. MOD:00584 4-sulfophenyl isothiocyanate derivatized residue

Table 586. Term [MOD:00584]
id	MOD:00584
name	4-sulfophenyl isothiocyanate derivatized residue
def	"A protein modification produced by formation of an adduct with 4-sulfophenyl isothiocyanate." [PubMed:14689565, PubMed:14745769, PubMed:16526082, UniMod:261]
synonym	"4-sulfophenyl isothiocyanate" RELATED UniMod-description []
synonym	"SPITC" RELATED PSI-MS-label []
xref	DiffAvg: "215.24"
xref	DiffFormula: "C 7 H 5 N 1 O 3 S 2"
xref	DiffMono: "214.971085"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00841 isothiocyanate reagent derivatized residue ! isothiocyanate reagent derivatized residue

2.585. MOD:00585 deuterium trisubstituted residue

Table 587. Term [MOD:00585]
id	MOD:00585
name	deuterium trisubstituted residue
def	"A protein modification that effectively substitutes three (2)H deuterium atoms for three (1)H protium atoms." [UniMod:262]
synonym	"D(H)3Res" EXACT PSI-MOD-label []
synonym	"Label:2H(3)" RELATED PSI-MS-label []
synonym	"Trideuteration" RELATED UniMod-description []
xref	DiffAvg: "3.02"
xref	DiffFormula: "(1)H -3 (2)H 3"
xref	DiffMono: "3.018830"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00786 deuterium substituted residue ! deuterium substituted residue

2.586. MOD:00586 phosphorylation to pyridyl thiol

Table 588. Term [MOD:00586]
id	MOD:00586
name	phosphorylation to pyridyl thiol
def	"modification from UniMod Chemical derivative" [UniMod:264]
synonym	"PET" RELATED PSI-MS-label []
synonym	"phosphorylation to pyridyl thiol" RELATED UniMod-description []
xref	DiffAvg: "121.20"
xref	DiffFormula: "C 7 H 7 N 1 O -1 S 1"
xref	DiffMono: "121.035006"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.587. MOD:00587 6x(13)C,4x(15)N labeled L-arginine

Table 589. Term [MOD:00587]
id	MOD:00587
name	6x(13)C,4x(15)N labeled L-arginine
def	"A protein modification that effectively converts an L-arginine residue to 6x(13)C, 4x(15)N labeled L-arginine." [OMSSA:137, PubMed:12716131, UniMod:267]
subset	PSI-MOD-slim
synonym	"13C(6) 15N(4) Silac label" RELATED UniMod-description []
synonym	"arg-13c6-15n4" EXACT OMSSA-label []
synonym	"Label:13C(6)15N(4)" RELATED PSI-MS-label []
xref	DiffAvg: "10.01"
xref	DiffFormula: "(12)C -6 (13)C 6 (14)N -4 (15)N 4"
xref	DiffMono: "10.008269"
xref	Formula: "(13)C 6 H 12 (15)N 4 O 1"
xref	MassAvg: "166.11"
xref	MassMono: "166.109380"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.588. MOD:00588 5x(13)C,1x(15)N labeled L-valine

Table 590. Term [MOD:00588]
id	MOD:00588
name	5x(13)C,1x(15)N labeled L-valine
def	"A protein modification that effectively converts an L-valine residue to 5x(13)C,1x(15)N labeled L-valine." [PubMed:12771378, UniMod:268#V]
synonym	"13C(5) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "6.01"
xref	DiffFormula: "(12)C -5 (13)C 5 (14)N -1 (15)N 1"
xref	DiffMono: "6.013809"
xref	Formula: "(13)C 5 H 9 (15)N 1 O 1"
xref	MassAvg: "105.08"
xref	MassMono: "105.082223"
xref	Origin: "V"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01809 5x(13)C,1x(15)N labeled residue ! 5x(13)C,1x(15)N labeled residue

2.589. MOD:00589 1x(13)C,1x(15)N labeled L-phenylalanine

Table 591. Term [MOD:00589]
id	MOD:00589
name	1x(13)C,1x(15)N labeled L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to (13)C,(15)N labeled L-phenylalanine." [PubMed:12771378, UniMod:269]
synonym	"13C(9) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(9)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "10.03"
xref	DiffFormula: "(12)C -9 (13)C 9 (14)N -1 (15)N 1"
xref	DiffMono: "10.027228"
xref	Formula: "(13)C 9 H 9 (15)N 1 O 1"
xref	MassAvg: "157.10"
xref	MassMono: "157.095642"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.590. MOD:00590 nucleophilic addtion to cytopiloyne

Table 592. Term [MOD:00590]
id	MOD:00590
name	nucleophilic addtion to cytopiloyne
def	"modification from UniMod Chemical derivative" [PubMed:15549660, UniMod:270]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.591. MOD:00591 nucleophilic addition to cytopiloyne+H2O

Table 593. Term [MOD:00591]
id	MOD:00591
name	nucleophilic addition to cytopiloyne+H2O
def	"modification from UniMod Chemical derivative" [PubMed:15549660, UniMod:271]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.592. MOD:00592 sulfonation of N-terminal

Table 594. Term [MOD:00592]
id	MOD:00592
name	sulfonation of N-terminal
def	"modification from UniMod Chemical derivative" [PubMed:12705581, PubMed:15732931, PubMed:16046801, UniMod:272]
synonym	"CAF" RELATED PSI-MS-label []
synonym	"sulfonation of N-terminus" RELATED UniMod-description []
xref	DiffAvg: "136.12"
xref	DiffFormula: "C 3 H 4 O 4 S 1"
xref	DiffMono: "135.983030"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00003 UniMod ! UniMod

2.593. MOD:00593 covalent modification of lysine by omega-maleimido alkanoyl N-hydroxysuccinimido esters

Table 595. Term [MOD:00593]
id	MOD:00593
name	covalent modification of lysine by omega-maleimido alkanoyl N-hydroxysuccinimido esters
def	"modification from UniMod Chemical derivative" [UniMod:273]
comment	J. Prot. Chem. 2, 263-277, 1983
synonym	"covalent modification of lysine by cross-linking reagent" RELATED UniMod-description []
synonym	"Xlink:SSD" RELATED PSI-MS-label []
xref	DiffAvg: "253.25"
xref	DiffFormula: "C 12 H 15 N 1 O 5"
xref	DiffMono: "253.095023"
xref	Formula: "C 18 H 27 N 3 O 6"
xref	MassAvg: "381.43"
xref	MassMono: "381.189986"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.594. MOD:00594 residues isobaric at 113.047678 Da

Table 596. Term [MOD:00594]
id	MOD:00594
name	residues isobaric at 113.047678 Da
def	"Natural or modified resiues with a mass of 113.047678 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00569 residues isobaric at a resolution below 0.000001 Da ! residues isobaric at a resolution below 0.000001 Da
is_a	MOD:00624 residues isobaric at 113.0-113.1 Da ! residues isobaric at 113.0-113.1 Da

2.595. MOD:00595 mannosylated residue

Table 597. Term [MOD:00595]
id	MOD:00595
name	mannosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an manose group through a glycosidic bond" [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ManRes" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00434 hexosylated residue ! hexosylated residue
is_a	MOD:00727 mannosylated ! mannosylated

2.596. MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue

Table 598. Term [MOD:00596]
id	MOD:00596
name	4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue
def	"A protein modification that is produced by formation of an adduct with 4-(2-aminoethyl)benzenesulfonyl fluoride, AEBS." [DeltaMass:235, PubMed:8597590, UniMod:276]
comment	From DeltaMass: Average Mass: 183 Average Mass Change:183 References:We have found that AEBSF modifies many proteins by covalent attachment, preferentially on Tyr, and to a lesser extent on Lys, His, and the amino-terminus. These modifications were identified by electrospray MS of the proteins (adds 183 Da per AEBS-group) and by peptide mapping and MS/MS. All the proteins we examined were modified after 24 hrs. at 4 C with 1 mM AEBSF in TRIS, pH 8.0. The reaction is 10-20x slower at pH 7; however AEBSF is quite stable in aqueous solution and the extent of to which the protein is modified continues to increase for several days. We have seen the addition of 10 or more AEBS-groups to proteins after prolonged storage. We found no equivalent modification from PMSF, probably because it degrades so quickly. We no longer use AEBSF, and urge caution to those who do. To address the problem, Boehringer Mannheim (now Roche Molecular Biochemicals) introduced Pefabloc PLUS which includes an additional component to compete for these side reactions. In our limited experience with Pefabloc PLUS, it reduces the +183 modifications, but does not always eliminate them. As a result, we prefer PMSF, despite its own set of drawbacks. We have never found PMSF-induced modification of proteins (except trypsin), probably due to its short half-life in aqeous solution.
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"AEBSF" EXACT DeltaMass-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01652 sulfonyl halide reagent derivatized residue ! sulfonyl halide reagent derivatized residue

2.597. MOD:00597 methyl methanethiosulfonate

Table 599. Term [MOD:00597]
id	MOD:00597
name	methyl methanethiosulfonate
def	"OBSOLETE because UniMod entry 277 redundant with UniMod 39. Remap to MOD:00110." [UniMod:277]
xref	DiffAvg: "46.09"
xref	DiffFormula: "C 1 H 2 S 1"
xref	DiffMono: "45.987721"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.598. MOD:00598 S-(2-hydroxyethyl)cysteine

Table 600. Term [MOD:00598]
id	MOD:00598
name	S-(2-hydroxyethyl)cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(2-hydroxyethyl)cysteine" [PubMed:15351294, UniMod:278]
comment	This modification of cysteine is produced by the reagent iodoethanol with triethylphosphine [JSG].
subset	PSI-MOD-slim
synonym	"Ethanolation of Cys" RELATED UniMod-description []
synonym	"Ethanolyl" RELATED PSI-MS-label []
xref	DiffAvg: "44.05"
xref	DiffFormula: "C 2 H 4 O 1"
xref	DiffMono: "44.026215"
xref	Formula: "C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "147.19"
xref	MassMono: "147.035400"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.599. MOD:00599 monomethylated residue

Table 601. Term [MOD:00599]
id	MOD:00599
name	monomethylated residue
def	"A protein modification that effectively replaces one hydrogen atom with one methyl group." [PubMed:11875433, UniMod:34]
subset	PSI-MOD-slim
synonym	"Me1Res" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2"
xref	DiffMono: "14.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue

2.600. MOD:00600 L-glutamic acid 5-ethyl ester

Table 602. Term [MOD:00600]
id	MOD:00600
name	L-glutamic acid 5-ethyl ester
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-ethyl ester." [DeltaMass:0, PubMed:9629898, UniMod:280#E]
comment	From DeltaMass: Average Mass: 28 with no citation. The UniMod citation refers to the formation of glutamate ethyl ester and not to either lysine or N-terminal alkylation. For dimethylated residues, see MOD:00429 and its children [JSG].
synonym	"Ethyl" EXACT DeltaMass-label []
synonym	"Ethyl" RELATED PSI-MS-label []
synonym	"Ethylation" RELATED UniMod-description []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "C 7 H 11 N 1 O 3"
xref	MassAvg: "157.17"
xref	MassMono: "157.073893"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01339 ethylated residue ! ethylated residue

2.601. MOD:00601 cyclized residue

Table 603. Term [MOD:00601]
id	MOD:00601
name	cyclized residue
def	"A protein modification that effectively produces an heterocyclic amino acid with a covalent bond between the side chain and either its alpha amino or 1-carboxyl group, possibly breaking the peptide chain." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"CycRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.602. MOD:00602 N-methylated residue

Table 604. Term [MOD:00602]
id	MOD:00602
name	N-methylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue amino or imino group with an methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NMeRes" EXACT PSI-MOD-label []
is_a	MOD:00427 methylated residue ! methylated residue

2.603. MOD:00603 N-ethylation

Table 605. Term [MOD:00603]
id	MOD:00603
name	N-ethylation
def	"OBSOLETE because UniMod entry 283 is redundant with UniMod 280. Remap to MOD:00600" [UniMod:283]
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_obsolete	true

2.604. MOD:00604 2x(2)H monomethylated L-lysine

Table 606. Term [MOD:00604]
id	MOD:00604
name	2x(2)H monomethylated L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 2x(2)H labeled monomethylated L-lysine." [PubMed:15525938, UniMod:284]
synonym	"Deuterium Methylation of Lysine" RELATED UniMod-description []
synonym	"Methyl:2H(2)" RELATED PSI-MS-label []
xref	DiffAvg: "16.03"
xref	DiffFormula: "C 1 (2)H 2"
xref	DiffMono: "16.028204"
xref	Formula: "C 7 (1)H 12 (2)H 2 N 2 O 1"
xref	MassAvg: "144.12"
xref	MassMono: "144.123167"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
relationship	derives_from MOD:00085 N6-methyl-L-lysine ! N6-methyl-L-lysine

2.605. MOD:00605 Sulfanilic Acid (SA), light C12

Table 607. Term [MOD:00605]
id	MOD:00605
name	Sulfanilic Acid (SA), light C12
def	"modification from UniMod Chemical derivative, C-Terminal/Glutamate/Aspartate sulfonation" [UniMod:285]
synonym	"Light Sulfanilic Acid (SA) C12" RELATED UniMod-description []
synonym	"SulfanilicAcid" RELATED PSI-MS-label []
xref	DiffAvg: "155.17"
xref	DiffFormula: "C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "155.004099"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.606. MOD:00606 Sulfanilic Acid (SA), heavy C13

Table 608. Term [MOD:00606]
id	MOD:00606
name	Sulfanilic Acid (SA), heavy C13
def	"modification from UniMod Chemical derivative" [PubMed:9254591, UniMod:286]
synonym	"Heavy Sulfanilic Acid (SA) C13" RELATED UniMod-description []
synonym	"SulfanilicAcid:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "161.02"
xref	DiffFormula: "(13)C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "161.024228"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.607. MOD:00607 dioxoindolealanine lactone

Table 609. Term [MOD:00607]
id	MOD:00607
name	dioxoindolealanine lactone
def	"modification from UniMod Chemical derivative" [PubMed:7949339, UniMod:288]
comment	UniMod name, formula, and terminal specification corrected. Formula corresponded to uncleaved intermediate [JSG].
synonym	"Trp→Oxolactone" RELATED PSI-MS-label []
synonym	"Tryptophan oxidation to oxolactone" RELATED UniMod-description []
xref	DiffAvg: "30.99"
xref	DiffFormula: "H -1 O 2"
xref	DiffMono: "30.982004"
xref	Formula: "C 11 H 9 N 2 O 3"
xref	MassAvg: "217.20"
xref	MassMono: "217.061317"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.608. MOD:00608 biotin polyethyleneoxide amine

Table 610. Term [MOD:00608]
id	MOD:00608
name	biotin polyethyleneoxide amine
def	"modification from UniMod Chemical derivative" [UniMod:289]
synonym	"Biotin polyethyleneoxide amine" RELATED UniMod-description []
synonym	"Biotin-PEO-Amine" RELATED UniMod-interim []
xref	DiffAvg: "356.49"
xref	DiffFormula: "C 16 H 28 N 4 O 3 S 1"
xref	DiffMono: "356.188212"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.609. MOD:00609 Pierce EZ-Link Biotin-HPDP

Table 611. Term [MOD:00609]
id	MOD:00609
name	Pierce EZ-Link Biotin-HPDP
def	"modification from UniMod Chemical derivative" [UniMod:290]
synonym	"Biotin-HPDP" RELATED UniMod-interim []
synonym	"Pierce EZ-Link Biotin-HPDP" RELATED UniMod-description []
xref	DiffAvg: "428.61"
xref	DiffFormula: "C 19 H 32 N 4 O 3 S 2"
xref	DiffMono: "428.191583"
xref	Formula: "C 22 H 37 N 5 O 4 S 3"
xref	MassAvg: "531.75"
xref	MassMono: "531.200768"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.610. MOD:00610 cysteinyl mercury

Table 612. Term [MOD:00610]
id	MOD:00610
name	cysteinyl mercury
def	"modification from UniMod Chemical derivative" [PubMed:10695144, UniMod:291]
synonym	"Delta:Hg(1)" RELATED PSI-MS-label []
synonym	"Mercury Mercaptan" RELATED UniMod-description []
xref	DiffAvg: "200.59"
xref	DiffFormula: "Hg 1"
xref	DiffMono: "201.970643"
xref	Formula: "C 3 H 5 Hg 1 N 1 O 1 S 1"
xref	MassAvg: "303.73"
xref	MassMono: "304.979828"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01075 mercury containing modified residue ! mercury containing modified residue

2.611. MOD:00611 iodouridine monophosphate derivatized residue

Table 613. Term [MOD:00611]
id	MOD:00611
name	iodouridine monophosphate derivatized residue
def	"A protein modification that is produced by reaction of iodouridine monophosphate, or a polynucleotide containing iodouridine, with a residue." [PubMed:11112526, PubMed:11567090, PubMed:6540775, UniMod:292]
synonym	"Cross-link of (Iodo)-uracil MP with W,F,Y" RELATED UniMod-description []
synonym	"IodoU-AMP" RELATED PSI-MS-label []
xref	DiffAvg: "322.17"
xref	DiffFormula: "C 9 H 11 N 2 O 9 P 1"
xref	DiffMono: "322.020217"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.612. MOD:00612 3-(carboxamidomethylthio)propanoylated residue

Table 614. Term [MOD:00612]
id	MOD:00612
name	3-(carboxamidomethylthio)propanoylated residue
def	"A protein modification that is produced by derivatization of a residue with 3,3-dithiobis[sulfosuccinimidyl propanoate], DTSSP, or with Pierce EZ-Link Sulfo-NHS-SS-Biotin reagent, sulfosuccinimidyl 3-[(2-[biotinamido]ethyl)disulfanyl]propanoate, followed by reduction with dithiothreitol and then reaction with iodoacetamide." [PubMed:15121203, UniMod:293]
synonym	"3-(carbamidomethylthio)propanoyl" RELATED UniMod-description []
synonym	"CAMthiopropanoyl" RELATED PSI-MS-label []
xref	DiffAvg: "145.18"
xref	DiffFormula: "C 5 H 7 N 1 O 2 S 1"
xref	DiffMono: "145.019749"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.613. MOD:00613 biotinoyl-iodoacetyl-ethylenediamine

Table 615. Term [MOD:00613]
id	MOD:00613
name	biotinoyl-iodoacetyl-ethylenediamine
def	"modification from UniMod Chemical derivative" [PubMed:10906242, UniMod:294]
synonym	"biotinoyl-iodoacetyl-ethylenediamine" RELATED UniMod-description []
synonym	"IED-Biotin" RELATED PSI-MS-label []
xref	DiffAvg: "326.42"
xref	DiffFormula: "C 14 H 22 N 4 O 3 S 1"
xref	DiffMono: "326.141262"
xref	Formula: "C 17 H 27 N 5 O 4 S 2"
xref	MassAvg: "429.55"
xref	MassMono: "429.150446"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.614. MOD:00614 fucosylated

Table 616. Term [MOD:00614]
id	MOD:00614
name	fucosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a fucose (6-deoxy-D-galactose) group through a glycosidic bond." [PubMed:11344537, PubMed:15189151, UniMod:295]
subset	PSI-MOD-slim
synonym	"dHex" RELATED PSI-MS-label []
synonym	"Fuc" EXACT PSI-MOD-label []
synonym	"Fucose" RELATED UniMod-description []
xref	DiffAvg: "146.14"
xref	DiffFormula: "C 6 H 10 O 4"
xref	DiffMono: "146.057909"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00736 deoxyhexosylated ! deoxyhexosylated

2.615. MOD:00615 4-sulfophenyl isothiocyante modification to N-term R

Table 617. Term [MOD:00615]
id	MOD:00615
name	4-sulfophenyl isothiocyante modification to N-term R
def	"OBSOLETE because entry UniMod:261 site N-term R was abandoned. Remap to MOD:00584" [PubMed:14689565, UniMod:261]
xref	DiffAvg: "215.24"
xref	DiffFormula: "C 7 H 5 N 1 O 3 S 2"
xref	DiffMono: "214.971085"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_obsolete	true

2.616. MOD:00616 residues isobaric at a resolution below 0.1 Da

Table 618. Term [MOD:00616]
id	MOD:00616
name	residues isobaric at a resolution below 0.1 Da
def	"Natural or modified residues that are isobaric at a resolution below 0.1 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00538 protein modification categorized by isobaric sets ! protein modification categorized by isobaric sets

2.617. MOD:00617 3x(2)H residue methyl ester

Table 619. Term [MOD:00617]
id	MOD:00617
name	3x(2)H residue methyl ester
def	"A protein modification that effectively converts a residue containing common isotopes to a 3x(2)H labeled residue methyl ester." [OMSSA:21, UniMod:298]
synonym	"ctermpeptrideuteromethyl" EXACT OMSSA-label []
synonym	"deuterated methyl ester" RELATED UniMod-description []
synonym	"Methyl:2H(3)" RELATED PSI-MS-label []
xref	DiffAvg: "17.03"
xref	DiffFormula: "C 1 (1)H -1 (2)H 3"
xref	DiffMono: "17.034480"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "C-term"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue

2.618. MOD:00618 tryptophan carboxylation

Table 620. Term [MOD:00618]
id	MOD:00618
name	tryptophan carboxylation
def	"modification from UniMod Chemical derivative" [UniMod:299#W]
comment	There is no literature citation for this UniMod entry [JSG].
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxylation" RELATED UniMod-description []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 12 H 10 N 2 O 3"
xref	MassAvg: "230.22"
xref	MassMono: "230.069142"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.619. MOD:00619 hydroxylethanone

Table 621. Term [MOD:00619]
id	MOD:00619
name	hydroxylethanone
def	"OBSOLETE because entry 300 is redundant with UniMod 6 remap to MOD:01328" [UniMod:300]
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.620. MOD:00620 cysteine monobromobimane derivative

Table 622. Term [MOD:00620]
id	MOD:00620
name	cysteine monobromobimane derivative
def	"modification from UniMod Chemical derivative" [PubMed:7856876, UniMod:301]
comment	1-(bromomethyl)-2,6,7-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione, C 10 H 11 Br 1 N 2 O 2.
synonym	"Bromobimane" RELATED PSI-MS-label []
synonym	"Monobromobimane derivative" RELATED UniMod-description []
xref	DiffAvg: "190.20"
xref	DiffFormula: "C 10 H 10 N 2 O 2"
xref	DiffMono: "190.074228"
xref	Formula: "C 13 H 15 N 3 O 3 S 1"
xref	MassAvg: "293.34"
xref	MassMono: "293.083412"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.621. MOD:00621 menadione quinone derivative

Table 623. Term [MOD:00621]
id	MOD:00621
name	menadione quinone derivative
def	"modification from UniMod Chemical derivative" [PubMed:15939799, UniMod:302]
synonym	"Menadione" RELATED UniMod-interim []
synonym	"Menadione quinone derivative" RELATED UniMod-description []
xref	DiffAvg: "170.17"
xref	DiffFormula: "C 11 H 6 O 2"
xref	DiffMono: "170.036779"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.622. MOD:00622 cysteine mercaptoethanol

Table 624. Term [MOD:00622]
id	MOD:00622
name	cysteine mercaptoethanol
def	"modification from UniMod Chemical derivative" [DeltaMass:80, PubMed:12442261, UniMod:303]
comment	From DeltaMass: Average Mass: 76 Average Mass Change:76 PubMed:8019414.
synonym	"Beta mercaptoethanol adduct" EXACT DeltaMass-label []
synonym	"Cysteine mercaptoethanol" RELATED UniMod-description []
synonym	"DeStreak" RELATED PSI-MS-label []
xref	DiffAvg: "76.11"
xref	DiffFormula: "C 2 H 4 O 1 S 1"
xref	DiffMono: "75.998286"
xref	Formula: "C 5 H 9 N 1 O 2 S 2"
xref	MassAvg: "179.25"
xref	MassMono: "179.007471"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.623. MOD:00623 fucosylated biantennary (-2 galactose)

Table 625. Term [MOD:00623]
id	MOD:00623
name	fucosylated biantennary (-2 galactose)
def	"modification from UniMod N-linked glycosylation" [UniMod:305]
synonym	"dHex(1)Hex(3)HexNAc(4)" RELATED PSI-MS-label []
synonym	"Fucosylated biantennary (-2 galactose)" RELATED UniMod-description []
xref	DiffAvg: "1443.33"
xref	DiffFormula: "C 56 H 90 N 4 O 39"
xref	DiffMono: "1442.518219"
xref	Formula: "C 60 H 96 N 6 O 41"
xref	MassAvg: "1557.43"
xref	MassMono: "1556.561147"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.624. MOD:00624 residues isobaric at 113.0-113.1 Da

Table 626. Term [MOD:00624]
id	MOD:00624
name	residues isobaric at 113.0-113.1 Da
def	"Natural or modified residues with a mass of 113.0-113.1 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00616 residues isobaric at a resolution below 0.1 Da ! residues isobaric at a resolution below 0.1 Da

2.625. MOD:00625 N-methylmaleimide derivatized residue

Table 627. Term [MOD:00625]
id	MOD:00625
name	N-methylmaleimide derivatized residue
def	"modification from UniMod Chemical derivative" [UniMod:314]
synonym	"Nmethylmaleimide" RELATED PSI-MS-label []
synonym	"Nmethylmaleimide" RELATED UniMod-description []
xref	DiffAvg: "111.10"
xref	DiffFormula: "C 5 H 5 N 1 O 2"
xref	DiffMono: "111.032028"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.626. MOD:00626 fluorescein-5-thiosemicarbazide

Table 628. Term [MOD:00626]
id	MOD:00626
name	fluorescein-5-thiosemicarbazide
def	"modification from UniMod Chemical derivative" [PubMed:2883911, UniMod:478]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.627. MOD:00627 2,5-dimethylpyrrole lysine from 2,5-hexanedione adduct

Table 629. Term [MOD:00627]
id	MOD:00627
name	2,5-dimethylpyrrole lysine from 2,5-hexanedione adduct
def	"modification from UniMod Chemical derivative" [UniMod:316]
comment	There is no citation for this UniMod entry. Add PubMed:7981420, correct spelling [JSG].
synonym	"(2S)-2-amino-6-(2,5-dimethylpyrrolidin-1-yl)hexanoic acid" EXACT PSI-MOD-alternate []
synonym	"2,5-dimethypyrrole" RELATED UniMod-description []
synonym	"6-(2,5-dimethylpyrrolidin-1-yl)norleucine" EXACT PSI-MOD-alternate []
synonym	"DimethylpyrroleAdduct" RELATED PSI-MS-label []
xref	DiffAvg: "78.11"
xref	DiffFormula: "C 6 H 6"
xref	DiffMono: "78.046950"
xref	Formula: "C 12 H 18 N 2 O 1"
xref	MassAvg: "206.29"
xref	MassMono: "206.141913"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.628. MOD:00628 Hex2

Table 630. Term [MOD:00628]
id	MOD:00628
name	Hex2
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with two hexose sugar groups through glycosidic bonds" [PubMed:18688235]
xref	DiffAvg: "324.28"
xref	DiffFormula: "C 12 H 20 O 10"
xref	DiffMono: "324.105647"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.629. MOD:00629 MDA adduct +62

Table 631. Term [MOD:00629]
id	MOD:00629
name	MDA adduct +62
def	"modification from UniMod Chemical derivative" [UniMod:318]
comment	Usually major adduct formed from malondialdehyde (MDA) with the amino group of lysine residues [UniProt].
synonym	"Delta:H(2)C(5)" RELATED PSI-MS-label []
synonym	"MDA adduct +62" RELATED UniMod-description []
xref	DiffAvg: "62.07"
xref	DiffFormula: "C 5 H 2"
xref	DiffMono: "62.015650"
xref	Formula: "C 11 H 14 N 2 O 1"
xref	MassAvg: "190.25"
xref	MassMono: "190.110613"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.630. MOD:00630 C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine.

Table 632. Term [MOD:00630]
id	MOD:00630
name	C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine.
def	"modification from UniMod Chemical derivative" [PubMed:9328283, UniMod:319]
comment	This is not a legitimate ontological entry and will become obsolete when the children are reassigned [JSG]
synonym	"Delta:H(2)C(3)O(1)" RELATED PSI-MS-label []
synonym	"MDA adduct +54" RELATED UniMod-description []
xref	DiffAvg: "54.05"
xref	DiffFormula: "C 3 H 2 O 1"
xref	DiffMono: "54.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.631. MOD:00631 hydrolyzed N-ethylmaleimide adduct

Table 633. Term [MOD:00631]
id	MOD:00631
name	hydrolyzed N-ethylmaleimide adduct
def	"modification from UniMod Chemical derivative" [UniMod:320]
comment	N-ethylmaeimide adduct + H20 (a mixture of isobaric products) [JSG].
synonym	"Nethylmaleimide+water" RELATED PSI-MS-label []
synonym	"Nethylmaleimidehydrolysis" RELATED UniMod-description []
xref	DiffAvg: "143.14"
xref	DiffFormula: "C 6 H 9 N 1 O 3"
xref	DiffMono: "143.058243"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.632. MOD:00632 N-succinimide

Table 634. Term [MOD:00632]
id	MOD:00632
name	N-succinimide
def	"OBSOLETE because this chemical derivative modification from UniMod 321 is deprecated." [UniMod:321]
xref	DiffAvg: "-17.01"
xref	DiffFormula: "H -1 O -1"
xref	DiffMono: "-17.002740"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.633. MOD:00633 bis-N-I-sulfonerahodamine

Table 635. Term [MOD:00633]
id	MOD:00633
name	bis-N-I-sulfonerahodamine
def	"modification from UniMod Chemical derivative" [UniMod:323]
comment	Invitrogen B-10621, a red fluorescent cross-linking reagent (only link to Cys is indicated) [UniMod].
synonym	"bis-((N-iodoacetyl)piperazinyl)sulfonerhodamine" EXACT PSI-MOD-alternate []
synonym	"bis-N-I-sulfonerahodamine" RELATED UniMod-description []
synonym	"Xlink:B10621" RELATED PSI-MS-label []
xref	DiffAvg: "713.57"
xref	DiffFormula: "C 31 H 30 I 1 N 4 O 6 S 1"
xref	DiffMono: "713.093078"
xref	Formula: "C 34 H 35 I 1 N 5 O 7 S 2"
xref	MassAvg: "816.71"
xref	MassMono: "816.102263"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.634. MOD:00634 dimethyl 3,3'-dithiobispropionimidate

Table 636. Term [MOD:00634]
id	MOD:00634
name	dimethyl 3,3'-dithiobispropionimidate
def	"modification from UniMod Chemical derivative" [PubMed:770170, UniMod:324]
comment	Pierce reagent, needs sites for N, Q, R, K, and N-term [JSG].
synonym	"dimethyl 3,3'-dithiobispropionimidate" RELATED UniMod-description []
synonym	"DTBP" RELATED UniMod-interim []
xref	DiffAvg: "123.60"
xref	DiffFormula: "C 3 Cl 1 H 6 N 1 S 1"
xref	DiffMono: "122.990948"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.635. MOD:00635 10-fluoroethoxyphosphinyl-N-(biotinamidopentyl)decanamide

Table 637. Term [MOD:00635]
id	MOD:00635
name	10-fluoroethoxyphosphinyl-N-(biotinamidopentyl)decanamide
def	"modification from UniMod Chemical derivative" [PubMed:10611275, UniMod:325]
synonym	"10-ethoxyphosphinyl-N-(biotinamidopentyl)decanamide" RELATED UniMod-description []
synonym	"FP-Biotin" RELATED UniMod-interim []
xref	DiffAvg: "572.75"
xref	DiffFormula: "C 27 H 49 N 4 O 5 P 1 S 1"
xref	DiffMono: "572.316128"
xref	Formula: "C 30 H 54 N 5 O 7 P 1 S 1"
xref	MassAvg: "659.82"
xref	MassMono: "659.348157"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.636. MOD:00636 S-ethylcysteine (Ser)

Table 638. Term [MOD:00636]
id	MOD:00636
name	S-ethylcysteine (Ser)
def	"A protein modification that effectively converts an L-serine residue to S-ethylcysteine." [UniMod:327]
comment	Modification from UniMod. Phosphoserine is converted to dehydroalanine then by Michael addition of ethanethiol to S-ethylcysteine. Needs parent and sibling for S-ethyl-cysteine.
synonym	"Delta:H(4)C(2)O(-1)S(1)" RELATED PSI-MS-label []
synonym	"S-Ethylcystine from Serine" RELATED UniMod-description []
xref	DiffAvg: "44.11"
xref	DiffFormula: "C 2 H 4 O -1 S 1"
xref	DiffMono: "44.008457"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.040485"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.637. MOD:00637 1x(13)C,3x(2)H labeled monomethylated L-arginine

Table 639. Term [MOD:00637]
id	MOD:00637
name	1x(13)C,3x(2)H labeled monomethylated L-arginine
def	"A protein modification that effectively replaces one hydrogen atom of an L-arginine residue with a (13)C,3x(2)H labeled methyl group to form a 1x(13)C,3x(2)H labeled monomethylated L-arginine." [UniMod:329]
synonym	"Methyl:2H(3)13C(1)" RELATED PSI-MS-label []
synonym	"monomethylated arginine" RELATED UniMod-description []
xref	DiffAvg: "18.04"
xref	DiffFormula: "(13)C 1 (1)H -1 (2)H 3"
xref	DiffMono: "18.037835"
xref	Formula: "(12)C 6 (13)C 1 (1)H 11 (2)H 3 N 4 O 1"
xref	MassAvg: "174.14"
xref	MassMono: "174.138946"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
relationship	derives_from MOD:00414 monomethylated L-arginine ! monomethylated L-arginine

2.638. MOD:00638 2x(13)C,6x(2)H labeled dimethylated L-arginine

Table 640. Term [MOD:00638]
id	MOD:00638
name	2x(13)C,6x(2)H labeled dimethylated L-arginine
def	"A protein modification that effectively replaces two hydrogen atoms of an L-arginine residue with two (13)C,3x(2)H labeled methyl groups to form a 2x(13)C,6x(2)H labeled dimethylated L-arginine." [PubMed:15782174, UniMod:330]
synonym	"Dimethyl:2H(6)13C(2)" RELATED PSI-MS-label []
synonym	"dimethylated arginine" RELATED UniMod-description []
xref	DiffAvg: "36.08"
xref	DiffFormula: "(13)C 2 (1)H -2 (2)H 6"
xref	DiffMono: "36.075670"
xref	Formula: "(12)C 6 (13)C 2 (1)H 10 (2)H 6 N 4 O 1"
xref	MassAvg: "192.18"
xref	MassMono: "192.176781"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
relationship	derives_from MOD:00783 dimethylated L-arginine ! dimethylated L-arginine

2.639. MOD:00639 thiophosphate labeled with biotin-HPDP

Table 641. Term [MOD:00639]
id	MOD:00639
name	thiophosphate labeled with biotin-HPDP
def	"modification from UniMod Chemical derivative" [UniMod:332]
synonym	"Thiophos-S-S-biotin" RELATED PSI-MS-label []
synonym	"thiophosphate labeled with biotin-HPDP" RELATED UniMod-description []
xref	DiffAvg: "525.66"
xref	DiffFormula: "C 19 H 34 N 4 O 5 P 1 S 3"
xref	DiffMono: "525.142895"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.640. MOD:00640 6-N-biotinylaminohexyl isopropyl phosphorofluoridate

Table 642. Term [MOD:00640]
id	MOD:00640
name	6-N-biotinylaminohexyl isopropyl phosphorofluoridate
def	"modification from UniMod Chemical derivative" [UniMod:333]
synonym	"6-N-biotinylaminohexyl isopropyl phosphate" RELATED UniMod-description []
synonym	"Can-FP-biotin" RELATED UniMod-interim []
xref	DiffAvg: "467.54"
xref	DiffFormula: "C 19 F 1 H 35 N 3 O 5 P 1 S 1"
xref	DiffMono: "467.201907"
xref	Formula: "C 22 F 1 H 40 N 4 O 7 P 1 S 1"
xref	MassAvg: "554.62"
xref	MassMono: "554.233935"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.641. MOD:00641 CAMthiopropanoyl of Lys

Table 643. Term [MOD:00641]
id	MOD:00641
name	CAMthiopropanoyl of Lys
def	"OBSOLETE because UniMod entry 334 is merged with UniMod 293. Remap to MOD:00612" [UniMod:334]
xref	DiffAvg: "146.18"
xref	DiffFormula: "C 5 H 8 N 1 O 2 S 1"
xref	DiffMono: "146.027574"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.642. MOD:00642 reduced 4-hydroxynonenal adduct

Table 644. Term [MOD:00642]
id	MOD:00642
name	reduced 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of a residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4." [PubMed:11910026, PubMed:15133838, UniMod:335]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"HNE+Delta:H(2)" RELATED PSI-MS-label []
synonym	"reduced 4-Hydroxynonenal" RELATED UniMod-description []
xref	DiffAvg: "158.24"
xref	DiffFormula: "C 9 H 18 O 2"
xref	DiffMono: "158.130680"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue
relationship	derives_from MOD:00446 4-hydroxynonenal adduct ! 4-hydroxynonenal adduct

2.643. MOD:00643 methylamine Michael addition derivatized residue

Table 645. Term [MOD:00643]
id	MOD:00643
name	methylamine Michael addition derivatized residue
def	"modification from UniMod Artifact" [PubMed:11968134, UniMod:337]
synonym	"Methylamine" RELATED PSI-MS-label []
synonym	"Michael addition with methylamine" RELATED UniMod-description []
xref	DiffAvg: "13.04"
xref	DiffFormula: "C 1 H 3 N 1 O -1"
xref	DiffMono: "13.031634"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00003 UniMod ! UniMod

2.644. MOD:00644 O-acetylated residue

Table 646. Term [MOD:00644]
id	MOD:00644
name	O-acetylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with an acetoxy group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OAcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.645. MOD:00645 S-acetylated residue

Table 647. Term [MOD:00645]
id	MOD:00645
name	S-acetylated residue
def	"A protein modification that effectively replaces a residue sulfanyl group with an acetylsulfanyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SAcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 O 1 S 0"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00672 S-acylated residue ! S-acylated residue

2.646. MOD:00646 acetylated L-cysteine

Table 648. Term [MOD:00646]
id	MOD:00646
name	acetylated L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to either N-acetyl-L-cysteine or S-acetyl-L-cysteine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"AcCys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1 S 0"
xref	DiffMono: "42.010565"
xref	Formula: "C 5 H 7 N 1 O 2 S 1"
xref	MassAvg: "145.18"
xref	MassMono: "145.019749"
xref	Origin: "C"
xref	Source: "natural"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.647. MOD:00647 acetylated L-serine

Table 649. Term [MOD:00647]
id	MOD:00647
name	acetylated L-serine
def	"A protein modification that effectively converts an L-serine residue to either N-acetyl-L-serine, O-acetyl-L-serine, or N,O-diacetyl-L-serine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"AcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "natural"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.648. MOD:00648 N,O-diacetylated L-serine

Table 650. Term [MOD:00648]
id	MOD:00648
name	N,O-diacetylated L-serine
def	"A protein modification that effectively converts an L-serine residue to N,O-diacetyl-L-serine." [PubMed:16731519, PubMed:489587, PubMed:7309355, RESID:AA0051#var, RESID:AA0364#var]
comment	The samples were prepared using glacial acetic acid, and were probably artifactual [JSG].
synonym	"(S)-2-acetamido-3-acetyloxypropanoic acid" EXACT PSI-MOD-alternate []
synonym	"N,O-diacetyl-L-serine" EXACT PSI-MOD-alternate []
synonym	"N,O-diacetylserine" EXACT PSI-MOD-alternate []
synonym	"NOAc2Ser" EXACT PSI-MOD-label []
xref	DiffAvg: "84.07"
xref	DiffFormula: "C 4 H 4 N 0 O 2"
xref	DiffMono: "84.021129"
xref	Formula: "C 7 H 10 N 1 O 4"
xref	MassAvg: "172.16"
xref	MassMono: "172.060983"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00408 N-acetylated residue ! N-acetylated residue
is_a	MOD:00644 O-acetylated residue ! O-acetylated residue
is_a	MOD:00647 acetylated L-serine ! acetylated L-serine
relationship	has_functional_parent MOD:00060 N-acetyl-L-serine ! N-acetyl-L-serine
relationship	has_functional_parent MOD:00369 O-acetyl-L-serine ! O-acetyl-L-serine

2.649. MOD:00649 acylated residue

Table 651. Term [MOD:00649]
id	MOD:00649
name	acylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"AcylRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.650. MOD:00650 N-myristoylated residue

Table 652. Term [MOD:00650]
id	MOD:00650
name	N-myristoylated residue
def	"A protein modification that effectively replaces a residue amino group with a myristoylamino group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NMyrRes" EXACT PSI-MOD-label []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 O 1"
xref	DiffMono: "210.198365"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00438 myristoylated residue ! myristoylated residue
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.651. MOD:00651 N-palmitoylated residue

Table 653. Term [MOD:00651]
id	MOD:00651
name	N-palmitoylated residue
def	"A protein modification that effectively replaces a residue amino group with a palmitoylamino group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NPamRes" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00440 palmitoylated residue ! palmitoylated residue
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.652. MOD:00652 O-palmitoylated residue

Table 654. Term [MOD:00652]
id	MOD:00652
name	O-palmitoylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a palmitoyloxy group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OPamRes" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 O 1"
xref	DiffMono: "238.229666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00440 palmitoylated residue ! palmitoylated residue
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.653. MOD:00653 S-palmitoylated residue

Table 655. Term [MOD:00653]
id	MOD:00653
name	S-palmitoylated residue
def	"A protein modification that effectively replaces a residue sulfanyl group with an palmitoylsulfanyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SPamRes" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00440 palmitoylated residue ! palmitoylated residue
is_a	MOD:00672 S-acylated residue ! S-acylated residue

2.654. MOD:00654 S-methylated residue

Table 656. Term [MOD:00654]
id	MOD:00654
name	S-methylated residue
def	"a protein modification that effectively replaces a sulfanyl group with a methylsulfanyl group" [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SMeRes" EXACT PSI-MOD-label []
is_a	MOD:00427 methylated residue ! methylated residue

2.655. MOD:00655 S-myristoylated residue

Table 657. Term [MOD:00655]
id	MOD:00655
name	S-myristoylated residue
def	"A protein modification that effectively replaces a residue sulfanyl group with an myristoylsulfanyl group." [PubMed:18688235]
synonym	"SMyrRes" EXACT PSI-MOD-label []
xref	DiffAvg: "210.36"
xref	DiffFormula: "C 14 H 26 O 1 S 0"
xref	DiffMono: "210.198365"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00438 myristoylated residue ! myristoylated residue
is_a	MOD:00672 S-acylated residue ! S-acylated residue

2.656. MOD:00656 C-methylated residue

Table 658. Term [MOD:00656]
id	MOD:00656
name	C-methylated residue
def	"A protein modification that effectively replaces a residue hydrocarbyl hydrogen with an methyl group." [PubMed:18688235]
synonym	"CMeRes" EXACT PSI-MOD-label []
is_a	MOD:00427 methylated residue ! methylated residue

2.657. MOD:00657 L-glutamic acid 5-methyl ester (Gln)

Table 659. Term [MOD:00657]
id	MOD:00657
name	L-glutamic acid 5-methyl ester (Gln)
def	"A protein modification that effectively converts an L-glutamine residue to L-glutamate 5-methyl ester." [PubMed:16888, PubMed:6300110, RESID:AA0072#GLN, UniMod:528]
comment	This is known to be a natural modification of glutamine in prokaryotes.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-methoxy-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(5)-methyl L-hydrogen glutamate" EXACT RESID-alternate []
synonym	"2-aminopentanedioic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"5-methyl L-2-aminoglutarate" EXACT RESID-alternate []
synonym	"5-methyl L-glutamate" EXACT RESID-alternate []
synonym	"deamidated 5-methyl esterified glutamine" EXACT PSI-MOD-alternate []
synonym	"Deamidation followed by a methylation" RELATED UniMod-description []
synonym	"glutamic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"glutamic acid gamma-methyl ester" EXACT RESID-alternate []
synonym	"L-glutamic acid 5-methyl ester" EXACT RESID-name []
synonym	"Methyl+Deamidated" RELATED PSI-MS-label []
synonym	"MOD_RES Glutamate methyl ester (Gln)" EXACT UniProt-feature []
synonym	"O5MeGlu(Gln)" EXACT PSI-MOD-label []
xref	DiffAvg: "15.01"
xref	DiffFormula: "C 1 H 1 N -1 O 1"
xref	DiffMono: "14.999666"
xref	Formula: "C 6 H 9 N 1 O 3"
xref	MassAvg: "143.14"
xref	MassMono: "143.058243"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01369 deamidated and methyl esterified residue ! deamidated and methyl esterified residue
is_a	MOD:01453 L-glutamic acid 5-methyl ester ! L-glutamic acid 5-methyl ester
relationship	has_functional_parent MOD:00659 methylated glutamine ! methylated glutamine

2.658. MOD:00658 methylated arginine

Table 660. Term [MOD:00658]
id	MOD:00658
name	methylated arginine
def	"A protein modification that effectively converts an L-arginine residue to a methylated arginine, either 5-methylargine, N5-methylarginine, or an omega-N-methylated L-arginine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeArg" EXACT PSI-MOD-label []
xref	Origin: "R"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.659. MOD:00659 methylated glutamine

Table 661. Term [MOD:00659]
id	MOD:00659
name	methylated glutamine
def	"A protein modification that effectively converts an L-glutamine residue to a methylated glutamine, either 2-methylated glutamine, N5-methylated glutamine, or methyl esterified deamidated glutamine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeGln" EXACT PSI-MOD-label []
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.660. MOD:00660 methylated cysteine

Table 662. Term [MOD:00660]
id	MOD:00660
name	methylated cysteine
def	"A protein modification that effectively converts an L-cysteine residue to a methylated cysteine, either S-methylcysteine, or cysteine methyl ester." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeCys" EXACT PSI-MOD-label []
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.661. MOD:00661 methylated histidine

Table 663. Term [MOD:00661]
id	MOD:00661
name	methylated histidine
def	"A protein modification that effectively converts an L-histidine residue to a methylated histidine, such as pros-methylhistidine, or tele-methylhistidine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeHis" EXACT PSI-MOD-label []
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.662. MOD:00662 methylated leucine

Table 664. Term [MOD:00662]
id	MOD:00662
name	methylated leucine
def	"A protein modification that effectively converts an L-leucine residue to a methylated leucine, either N-methylleucine, or leucine methyl ester." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeLeu" EXACT PSI-MOD-label []
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.663. MOD:00663 methylated lysine

Table 665. Term [MOD:00663]
id	MOD:00663
name	methylated lysine
def	"A protein modification that effectively converts an L-lysine residue to a methylated lysine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeLys" EXACT PSI-MOD-label []
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.664. MOD:00664 stereoisomerized residue

Table 666. Term [MOD:00664]
id	MOD:00664
name	stereoisomerized residue
def	"A protein modification that effectively replaces a residue L-enantiomer (stereoisomer) with a D-enantiomer or with a different diastereomeric isomer." [PubMed:18688235]
synonym	"D-Res" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.665. MOD:00665 methylated alanine

Table 667. Term [MOD:00665]
id	MOD:00665
name	methylated alanine
def	"A protein modification that effectively converts an L-alanine residue to a methylated alanine, such as N-methylalanine, N,N-dimethylalanine, or N,N,N-trimethylalanine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeAla" EXACT PSI-MOD-label []
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.666. MOD:00666 octanoylated residue

Table 668. Term [MOD:00666]
id	MOD:00666
name	octanoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an octanoyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OctRes" EXACT PSI-MOD-label []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1"
xref	DiffMono: "126.104465"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.667. MOD:00667 decanoylated residue

Table 669. Term [MOD:00667]
id	MOD:00667
name	decanoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a decanoyl group." [PubMed:18688235]
synonym	"DecRes" EXACT PSI-MOD-label []
xref	DiffAvg: "154.25"
xref	DiffFormula: "C 10 H 18 N 0 O 1"
xref	DiffMono: "154.135765"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.668. MOD:00668 O-decanoylated residue

Table 670. Term [MOD:00668]
id	MOD:00668
name	O-decanoylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a decanoyloxy group." [UniMod:449]
synonym	"Decanoyl" RELATED PSI-MS-label []
synonym	"lipid" RELATED UniMod-description []
synonym	"ODecRes" EXACT PSI-MOD-label []
xref	DiffAvg: "154.25"
xref	DiffFormula: "C 10 H 18 N 0 O 1"
xref	DiffMono: "154.135765"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00667 decanoylated residue ! decanoylated residue
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.669. MOD:00669 O-octanoylated residue

Table 671. Term [MOD:00669]
id	MOD:00669
name	O-octanoylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a octanoyloxy group." [UniMod:426]
subset	PSI-MOD-slim
synonym	"Octanoyl" RELATED PSI-MS-label []
synonym	"octanoyl" RELATED UniMod-description []
synonym	"OOctRes" EXACT PSI-MOD-label []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1"
xref	DiffMono: "126.104465"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00666 octanoylated residue ! octanoylated residue
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.670. MOD:00670 N-acylated residue

Table 672. Term [MOD:00670]
id	MOD:00670
name	N-acylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NAcylRes" EXACT PSI-MOD-label []
is_a	MOD:00649 acylated residue ! acylated residue

2.671. MOD:00671 O-acylated residue

Table 673. Term [MOD:00671]
id	MOD:00671
name	O-acylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a acyloxy group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OAcylRes" EXACT PSI-MOD-label []
is_a	MOD:00649 acylated residue ! acylated residue

2.672. MOD:00672 S-acylated residue

Table 674. Term [MOD:00672]
id	MOD:00672
name	S-acylated residue
def	"A protein modification that effectively replaces a residue sulfanyl group with an acylsulfanyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SAcylRes" EXACT PSI-MOD-label []
is_a	MOD:00649 acylated residue ! acylated residue

2.673. MOD:00673 methylated asparagine

Table 675. Term [MOD:00673]
id	MOD:00673
name	methylated asparagine
def	"A protein modification that effectively converts an L-asparagine residue to a methylated asparagine, such as N4-methyl-L-asparagine, or N4,N4-dimethyl-L-asparagine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeAsn" EXACT PSI-MOD-label []
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.674. MOD:00674 amidated residue

Table 676. Term [MOD:00674]
id	MOD:00674
name	amidated residue
def	"A protein modification that effectively replaces a carboxyl group with a carboxamido group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.675. MOD:00675 oxidized residue

Table 677. Term [MOD:00675]
id	MOD:00675
name	oxidized residue
def	"A protein modification that effectively either removes neutral hydrogen atoms (proton and electron), or adds oxygen atoms to a residue with or without the removal of hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OxRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.676. MOD:00676 oxygenated residue

Table 678. Term [MOD:00676]
id	MOD:00676
name	oxygenated residue
def	"A protein modification that effectively adds oxygen atoms to a residue with or without the removal of hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OxyRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00675 oxidized residue ! oxidized residue

2.677. MOD:00677 hydroxylated residue

Table 679. Term [MOD:00677]
id	MOD:00677
name	hydroxylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an hydroxyl group." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 16
subset	PSI-MOD-slim
synonym	"Hydroxylation (of delta C of Lysine, beta C of Tryptophan, C3 or C4 of Proline, beta C of Aspartate)" EXACT DeltaMass-label []
synonym	"HyRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue

2.678. MOD:00678 hydroxylated proline

Table 680. Term [MOD:00678]
id	MOD:00678
name	hydroxylated proline
def	"A protein modification that effectively converts an L-proline residue to an hydroxylated L-proline." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HyPro" EXACT PSI-MOD-label []
xref	Origin: "P"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.679. MOD:00679 carbon oxygenated residue

Table 681. Term [MOD:00679]
id	MOD:00679
name	carbon oxygenated residue
def	"A protein modification that effectively adds oxygen atoms to a carbon atom of a residue and removes hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"COxyRes" EXACT PSI-MOD-label []
is_a	MOD:00676 oxygenated residue ! oxygenated residue

2.680. MOD:00680 sulfur oxygenated residue

Table 682. Term [MOD:00680]
id	MOD:00680
name	sulfur oxygenated residue
def	"A protein modification that effectively adds oxygen atoms to a sulfur atom of a residue without removing hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SOxyRes" EXACT PSI-MOD-label []
is_a	MOD:00676 oxygenated residue ! oxygenated residue

2.681. MOD:00681 hydroxylated lysine

Table 683. Term [MOD:00681]
id	MOD:00681
name	hydroxylated lysine
def	"A protein modification that effectively converts an L-lysine residue to a hydroxylated L-lysine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HyLys" EXACT PSI-MOD-label []
xref	Origin: "K"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.682. MOD:00682 hydroxylated arginine

Table 684. Term [MOD:00682]
id	MOD:00682
name	hydroxylated arginine
def	"A protein modification that effectively converts an L-arginine residue to a hydroxylated L-arginine." [PubMed:18688235]
synonym	"HyArg" EXACT PSI-MOD-label []
xref	Origin: "R"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.683. MOD:00683 dehydrogenated residue

Table 685. Term [MOD:00683]
id	MOD:00683
name	dehydrogenated residue
def	"A protein modification that effectively removes neutral hydrogen atoms (proton and electron) from a residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"dHRes" EXACT PSI-MOD-label []
xref	Origin: "X"
is_a	MOD:00675 oxidized residue ! oxidized residue

2.684. MOD:00684 deamidated L-asparagine

Table 686. Term [MOD:00684]
id	MOD:00684
name	deamidated L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to L-aspartic acid." [PubMed:1097438, PubMed:339692, PubMed:4399050, PubMed:5764436, PubMed:6692818, PubMed:8089117, PubMed:9521123, PubMed:9582379, RESID:AA0004#ASN, UniMod:7#N]
comment	incidental to RESID:AA0059
subset	PSI-MOD-slim
synonym	"(2S)-2-aminobutanedioic acid" EXACT RESID-systematic []
synonym	"2-azanylbutanedioic acid" EXACT RESID-alternate []
synonym	"aminosuccinic acid" EXACT RESID-alternate []
synonym	"dNAsn" EXACT PSI-MOD-label []
synonym	"L-aspartic acid" EXACT RESID-name []
synonym	"MOD_RES Deamidated asparagine" EXACT UniProt-feature []
xref	DiffAvg: "0.98"
xref	DiffFormula: "C 0 H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00013 L-aspartic acid residue ! L-aspartic acid residue
is_a	MOD:00400 deamidated residue ! deamidated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.685. MOD:00685 deamidated L-glutamine

Table 687. Term [MOD:00685]
id	MOD:00685
name	deamidated L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to L-glutamic acid." [PubMed:1881881, PubMed:4565668, PubMed:4922541, PubMed:6692818, PubMed:9192900, PubMed:957425, RESID:AA0006#GLN, UniMod:7#Q]
subset	PSI-MOD-slim
synonym	"(2S)-2-aminopentanedioic acid" EXACT RESID-systematic []
synonym	"1-aminopropane-1,3-dicarboxylic acid" EXACT RESID-alternate []
synonym	"2-aminoglutaric acid" EXACT RESID-alternate []
synonym	"2-azanylpentanedioic acid" EXACT RESID-alternate []
synonym	"alpha-aminoglutaric acid" EXACT RESID-alternate []
synonym	"dNGln" EXACT PSI-MOD-label []
synonym	"glutaminic acid" EXACT RESID-alternate []
synonym	"L-glutamic acid" EXACT RESID-name []
synonym	"MOD_RES Deamidated glutamine" EXACT UniProt-feature []
xref	DiffAvg: "0.98"
xref	DiffFormula: "C 0 H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00015 L-glutamic acid residue ! L-glutamic acid residue
is_a	MOD:00400 deamidated residue ! deamidated residue

2.686. MOD:00686 L-selenocysteine (Cys)

Table 688. Term [MOD:00686]
id	MOD:00686
name	L-selenocysteine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to L-selenocysteine (not known as a natural, post-translational modification process)." [PubMed:10523135, PubMed:2037562, PubMed:2963330, PubMed:6217842, PubMed:6714945, RESID:AA0022#CYS, UniMod:162#C]
comment	This entry is for the artifactual formation of L-selenocysteine from cysteine. For encoded L-selenocysteine, use MOD:00031 [JSG].
synonym	"(2R)-2-amino-3-selanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-selanylpropanoic acid" EXACT RESID-alternate []
synonym	"3-selenylalanine" EXACT RESID-alternate []
synonym	"L-selenocysteine" EXACT RESID-name []
synonym	"NON_STD Selenocysteine" EXACT UniProt-feature []
synonym	"Sec(Cys)" EXACT PSI-MOD-label []
synonym	"SeCys" EXACT RESID-alternate []
synonym	"selenium cysteine" EXACT RESID-alternate []
xref	DiffAvg: "46.91"
xref	DiffFormula: "C 0 H 0 N 0 O 0 S -1 Se 1"
xref	DiffMono: "47.944450"
xref	Formula: "C 3 H 5 N 1 O 1 Se 1"
xref	MassAvg: "150.05"
xref	MassMono: "150.953635"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00007 selenium substitution for sulfur ! selenium substitution for sulfur
is_a	MOD:00031 L-selenocysteine residue ! L-selenocysteine residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.687. MOD:00687 thioether crosslinked residues

Table 689. Term [MOD:00687]
id	MOD:00687
name	thioether crosslinked residues
def	"A protein modification that crosslinks two residues by formation of a thioether bond between a cysteine thiol and either an alkyl C as in lanthionine, or an aryl C as 2'-(S-cysteinyl)-L-histidine." [PubMed:18688235]
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.688. MOD:00688 isopeptide crosslinked residues

Table 690. Term [MOD:00688]
id	MOD:00688
name	isopeptide crosslinked residues
def	"A protein modification that crosslinks two residues with an amide bond where either the donor amino or carboxyl is not an alpha group." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.689. MOD:00689 disulfide crosslinked residues

Table 691. Term [MOD:00689]
id	MOD:00689
name	disulfide crosslinked residues
def	"A protein modification that crosslinks two cysteine residues by formation of a disulfide bond." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01619 multisulfide crosslinked residues ! multisulfide crosslinked residues

2.690. MOD:00690 oxazole/thiazole ring crosslinked residues

Table 692. Term [MOD:00690]
id	MOD:00690
name	oxazole/thiazole ring crosslinked residues
def	"A protein modification that crosslinks two residues by formation of an oxazole or thiazole ring." [PubMed:18688235]
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.691. MOD:00691 5-imidazolinone ring crosslinked residues

Table 693. Term [MOD:00691]
id	MOD:00691
name	5-imidazolinone ring crosslinked residues
def	"A protein modification that crosslinks two residues by formation of an 5-imidazolinone ring." [PubMed:18688235]
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.692. MOD:00692 uncategorized crosslinked residues

Table 694. Term [MOD:00692]
id	MOD:00692
name	uncategorized crosslinked residues
def	"A protein crosslink modification that is not chemically categorized." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.693. MOD:00693 glycosylated residue

Table 695. Term [MOD:00693]
id	MOD:00693
name	glycosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"GlycoRes" EXACT PSI-MOD-label []
xref	Source: "natural"
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue

2.694. MOD:00694 halogen containing residue

Table 696. Term [MOD:00694]
id	MOD:00694
name	halogen containing residue
def	"A protein modification that effectively substitutes a halogen atom for a hydrogen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"halogenated residue" EXACT PSI-MOD-alternate []
synonym	"HalRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.695. MOD:00695 sulfated residue

Table 697. Term [MOD:00695]
id	MOD:00695
name	sulfated residue
def	"A protein modification that effectively substitutes a sulfonyl group for the hydrogen atom of a hydroxyl or sulfanyl group." [DeltaMass:0, PubMed:14752058, UniMod:40]
comment	From DeltaMass: Average Mass: 80.
subset	PSI-MOD-slim
synonym	"O-Sulfonation" RELATED UniMod-description []
synonym	"Sulfo" RELATED PSI-MS-label []
synonym	"SulfRes" EXACT PSI-MOD-label []
synonym	"Sulphonation (SO3H) (of PMC group)" EXACT DeltaMass-label []
xref	DiffAvg: "80.06"
xref	DiffFormula: "O 3 S 1"
xref	DiffMono: "79.956815"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue

2.696. MOD:00696 phosphorylated residue

Table 698. Term [MOD:00696]
id	MOD:00696
name	phosphorylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a phosphono group (H2PO3 or 'phosphate')." [DeltaMass:0, UniMod:21]
comment	From DeltaMass: Average Mass: 80.
subset	PSI-MOD-slim
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"Phosphorylation" RELATED UniMod-description []
synonym	"Phosphorylation (O of Serine, Threonine, Tyrosine and Aspartate, N epsilon of Lysine)" EXACT DeltaMass-label []
synonym	"PhosRes" EXACT PSI-MOD-label []
xref	DiffAvg: "79.98"
xref	DiffFormula: "H 1 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.697. MOD:00697 flavin modified residue

Table 699. Term [MOD:00697]
id	MOD:00697
name	flavin modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a flavin group." [UniMod:50]
subset	PSI-MOD-slim
synonym	"FAD" RELATED PSI-MS-label []
synonym	"Flavin adenine dinucleotide" RELATED UniMod-description []
synonym	"FlavRes" EXACT PSI-MOD-label []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2 S 0"
xref	DiffMono: "783.141485"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.698. MOD:00698 metal or metal cluster containing modified residue

Table 700. Term [MOD:00698]
id	MOD:00698
name	metal or metal cluster containing modified residue
def	"A protein modification that effectively substitutes a metal atom or a metal cluster for hydrogen atoms, or coordinates a metal ion." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MetalRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.699. MOD:00699 porphyrin modified residue

Table 701. Term [MOD:00699]
id	MOD:00699
name	porphyrin modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a porphyrin group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"PorphRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.700. MOD:00700 tetrapyrrole modified residue

Table 702. Term [MOD:00700]
id	MOD:00700
name	tetrapyrrole modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a tetrapyrrole group." [PubMed:18688235]
synonym	"TetrapyrRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.701. MOD:00701 nucleotide or nucleic acid modified residue

Table 703. Term [MOD:00701]
id	MOD:00701
name	nucleotide or nucleic acid modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a nucleotide or a polynucleotide through formation of either a phosphodiester bond, a phosphoramide ester bond, or a glycosidic bond." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NucRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.702. MOD:00702 isotope labeled residue

Table 704. Term [MOD:00702]
id	MOD:00702
name	isotope labeled residue
def	"A protein modification that effectively substitutes atoms of particular common isotopes with atoms or groups containing isotopes that are not the most common." [PubMed:18688235]
comment	In SILAC (stable isotope labelling of amino acids in cell culture), the label may be introduced either through labeling of an incorporated residue or labeling of the substrates in a metabolic modification. For isotope labeling introduced through a modification reagent see MOD:01426.
subset	PSI-MOD-slim
synonym	"IsoTagRes" EXACT PSI-MOD-label []
synonym	"SILAC" EXACT PSI-MOD-alternate []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.703. MOD:00703 isoprenylated residue

Table 705. Term [MOD:00703]
id	MOD:00703
name	isoprenylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a group derived from an isoprene polymer, such as a geranyl (C10), farnesyl (C15) or geranylgeranyl (C20) group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"IpRes" EXACT PSI-MOD-label []
is_a	MOD:00001 alkylated residue ! alkylated residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.704. MOD:00704 dehydrated residue

Table 706. Term [MOD:00704]
id	MOD:00704
name	dehydrated residue
def	"A protein modification that effectively forms a double bond by removing a molecule of water from a residue." [DeltaMass:0, UniMod:23]
subset	PSI-MOD-slim
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.705. MOD:00705 D-valine

Table 707. Term [MOD:00705]
id	MOD:00705
name	D-valine
def	"A protein modification that effectively converts an L-valine residue to D-valine." [ChEBI:30016, PubMed:15853325, RESID:AA0200]
synonym	"®-2-amino-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"alpha-amino-beta-methylbutyric acid" EXACT RESID-alternate []
synonym	"alpha-aminoisovaleric acid" EXACT RESID-alternate []
synonym	"D-Val" EXACT PSI-MOD-label []
synonym	"D-valine" EXACT RESID-name []
synonym	"MOD_RES D-valine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 5 H 9 N 1 O 1"
xref	MassAvg: "99.13"
xref	MassMono: "99.068414"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue

2.706. MOD:00706 dehydrogenated tyrosine

Table 708. Term [MOD:00706]
id	MOD:00706
name	dehydrogenated tyrosine
def	"A protein modification that effectively converts L-tyrosine to 2,3-didehydrotyrosine." [UniMod:401#Y]
subset	PSI-MOD-slim
synonym	"dHTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 9 H 7 N 1 O 2"
xref	MassAvg: "161.16"
xref	MassMono: "161.047678"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.707. MOD:00707 hydroxylated tyrosine

Table 709. Term [MOD:00707]
id	MOD:00707
name	hydroxylated tyrosine
def	"a protein modification that effectively converts an L-tyrosine residue to a multihydroxylated L-phenylalanine" [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HyTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.708. MOD:00708 sulfur oxygenated L-cysteine

Table 710. Term [MOD:00708]
id	MOD:00708
name	sulfur oxygenated L-cysteine
def	"A protein modification that effectively adds oxygen atoms to a sulfur atom of L-cysteine residue without removing hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SOxyCys" EXACT PSI-MOD-label []
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00680 sulfur oxygenated residue ! sulfur oxygenated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.709. MOD:00709 sulfur oxygenated L-methionine

Table 711. Term [MOD:00709]
id	MOD:00709
name	sulfur oxygenated L-methionine
def	"A protein modification that effectively adds oxygen atoms to a sulfur atom of L-methionine residue without removing hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SOxyMet" EXACT PSI-MOD-label []
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00680 sulfur oxygenated residue ! sulfur oxygenated residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.710. MOD:00710 protonated-dimethylated residue

Table 712. Term [MOD:00710]
id	MOD:00710
name	protonated-dimethylated residue
def	"A protein modification that effectively adds a proton and replaces two hydrogen atoms with two methyl groups." [PubMed:18688235]
comment	For N-terminal proline residues, dimethylation can effectively only be accomplished with a protonated imino group. This process accounts for both protonation and dimethylation. The alternative Me2Res process accounts only for dimethylation and not protonation.
subset	PSI-MOD-slim
synonym	"Me2+Res" EXACT PSI-MOD-label []
is_a	MOD:00429 dimethylated residue ! dimethylated residue

2.711. MOD:00711 trimethylated protonated-residue

Table 713. Term [MOD:00711]
id	MOD:00711
name	trimethylated protonated-residue
def	"A protein modification that effectively replaces three hydrogen atoms with three methyl groups, after a proton has been added to form an aminium group." [PubMed:18688235]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with a protonated primary amino group. This process accounts for both protonation and trimethylation. The alternative Me3Res process accounts only for trimethylation and not protonation.
subset	PSI-MOD-slim
synonym	"Me3+Res" EXACT PSI-MOD-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0 S 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00430 trimethylated residue ! trimethylated residue

2.712. MOD:00712 methylated proline

Table 714. Term [MOD:00712]
id	MOD:00712
name	methylated proline
def	"A protein modification that effectively converts an L-proline residue to a methylated proline, such as N,N-dimethylproline." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MePro" EXACT PSI-MOD-label []
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.713. MOD:00713 methylated glutamic acid

Table 715. Term [MOD:00713]
id	MOD:00713
name	methylated glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to a methylated glutamic acid, such as L-glutamate 5-methyl ester." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeGlu" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.714. MOD:00714 methylated glycine

Table 716. Term [MOD:00714]
id	MOD:00714
name	methylated glycine
def	"A protein modification that effectively converts a glycine residue to a methylated glycine, such as N-methylglycine." [PubMed:18688235]
synonym	"MeGly" EXACT PSI-MOD-label []
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.715. MOD:00715 methylated isoleucine

Table 717. Term [MOD:00715]
id	MOD:00715
name	methylated isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a methylated isoleucine residue, such as N-methyl-L-isoleucine." [PubMed:18688235]
synonym	"MeIle" EXACT PSI-MOD-label []
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue

2.716. MOD:00716 methylated methionine

Table 718. Term [MOD:00716]
id	MOD:00716
name	methylated methionine
def	"A protein modification that effectively converts an L-methionine residue to a methylated methionine, such as N-methyl-L-methionine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeMet" EXACT PSI-MOD-label []
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.717. MOD:00717 methylated phenylalanine

Table 719. Term [MOD:00717]
id	MOD:00717
name	methylated phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to a methylated phenylalanine, such as N-methyl-L-phenylalanine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MePhe" EXACT PSI-MOD-label []
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.718. MOD:00718 methylated tyrosine

Table 720. Term [MOD:00718]
id	MOD:00718
name	methylated tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to a methylated tyrosine, such as N-methyl-L-tyrosine." [PubMed:18688235]
synonym	"MeTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.719. MOD:00719 L-methionine sulfoxide

Table 721. Term [MOD:00719]
id	MOD:00719
name	L-methionine sulfoxide
def	"A protein modification that oxygenates an L-methionine residue to one of the diastereomeric L-methionine sulfoxide residues." [DeltaMass:177, OMSSA:1, PubMed:21406390, PubMed:22116028, RESID:AA0581, UniMod:35#M]
comment	From DeltaMass: Average Mass: 147 Formula:C5H9O1N2S Monoisotopic Mass Change:147.035 Average Mass Change:147.195 (formula incorrect, N and O reversed) References:PE Sciex.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-[®-methylsulfinyl]butanoic acid" EXACT RESID-systematic []
synonym	"L-methionine ®-S-oxide" EXACT RESID-alternate []
synonym	"L-methionine ®-sulfoxide" EXACT RESID-name []
synonym	"L-methionine S-oxide" EXACT PSI-MOD-alternate []
synonym	"L-methionine sulfoxide" EXACT PSI-MOD-alternate []
synonym	"Methionyl Sulfoxide" EXACT DeltaMass-label []
synonym	"MetO" EXACT PSI-MOD-label []
synonym	"MOD_RES Methionine ®-sulfoxide" EXACT UniProt-feature []
synonym	"Oxidation" RELATED PSI-MS-label []
synonym	"oxym" EXACT OMSSA-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S 0"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "147.19"
xref	MassMono: "147.035400"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00709 sulfur oxygenated L-methionine ! sulfur oxygenated L-methionine
is_a	MOD:01854 sulfur monooxygenated residue ! sulfur monooxygenated residue

2.720. MOD:00720 L-methionine ®-sulfoxide

Table 722. Term [MOD:00720]
id	MOD:00720
name	L-methionine ®-sulfoxide
def	"A protein modification that effectively oxygenates an L-methionine residue to L-methionine sulfoxide R-diastereomer." [ChEBI:45764, PubMed:21406390, PubMed:22116028, PubMed:23911929, RESID:AA0581]
synonym	"(2S)-2-amino-4-[®-methylsulfinyl]butanoic acid" EXACT RESID-systematic []
synonym	"L-methionine ®-S-oxide" EXACT RESID-alternate []
synonym	"L-methionine ®-sulfoxide" EXACT RESID-name []
synonym	"MOD_RES Methionine ®-sulfoxide" EXACT UniProt-feature []
synonym	"R-MetO" EXACT PSI-MOD-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S 0"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "147.19"
xref	MassMono: "147.035400"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00719 L-methionine sulfoxide ! L-methionine sulfoxide

2.721. MOD:00721 L-methionine (S)-sulfoxide

Table 723. Term [MOD:00721]
id	MOD:00721
name	L-methionine (S)-sulfoxide
def	"A protein modification that effectively oxygenates an L-methionine residue to L-methionine sulfoxide S-diastereomer." [PubMed:18688235]
synonym	"S-MetO" EXACT PSI-MOD-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S 0"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "147.19"
xref	MassMono: "147.035400"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00719 L-methionine sulfoxide ! L-methionine sulfoxide

2.722. MOD:00722 monomethylated L-glutamine

Table 724. Term [MOD:00722]
id	MOD:00722
name	monomethylated L-glutamine
def	"A protein modification that effectively replaces one hydrogen atom of an L-glutamine residue with one methyl group." [OMSSA:14, UniMod:34#Q]
subset	PSI-MOD-slim
synonym	"Me1Gln" EXACT PSI-MOD-label []
synonym	"methylq" EXACT OMSSA-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 10 N 2 O 2"
xref	MassAvg: "142.16"
xref	MassMono: "142.074228"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00659 methylated glutamine ! methylated glutamine

2.723. MOD:00723 N-acetylated L-lysine

Table 725. Term [MOD:00723]
id	MOD:00723
name	N-acetylated L-lysine
def	"A protein modification that effectively converts an L-lysine residue to either N2-acetyl-L-lysine, or N6-acetyl-L-lysine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NAcLys" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 15 N 2 O 2"
xref	MassAvg: "171.22"
xref	MassMono: "171.113353"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00408 N-acetylated residue ! N-acetylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.724. MOD:00724 N-methylated L-histidine

Table 726. Term [MOD:00724]
id	MOD:00724
name	N-methylated L-histidine
def	"A protein modification that effectively replaces one hydrogen atom on a nitrogen of an L-histidine residue with one methyl group." [OMSSA:74, UniMod:34#H]
subset	PSI-MOD-slim
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"methylh" EXACT OMSSA-label []
synonym	"NMeHis" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 9 N 3 O 1"
xref	MassAvg: "151.17"
xref	MassMono: "151.074562"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00661 methylated histidine ! methylated histidine

2.725. MOD:00725 complex glycosylation

Table 727. Term [MOD:00725]
id	MOD:00725
name	complex glycosylation
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a carbohydrate-like group linked through a glycosidic bond." [PubMed:18688235]
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.726. MOD:00726 glucosylated

Table 728. Term [MOD:00726]
id	MOD:00726
name	glucosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a glucose group through a glycosidic bond." [PubMed:18688235]
synonym	"Glc" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.727. MOD:00727 mannosylated

Table 729. Term [MOD:00727]
id	MOD:00727
name	mannosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a mannose group through a glycosidic bond," [PubMed:18688235]
synonym	"Man" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.728. MOD:00728 galactosylated

Table 730. Term [MOD:00728]
id	MOD:00728
name	galactosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a galactose group through a glycosidic bond." [PubMed:18688235]
synonym	"Gal" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.729. MOD:00729 pentosylated residue

Table 731. Term [MOD:00729]
id	MOD:00729
name	pentosylated residue
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a pentose sugar group through a glycosidic bond" [DeltaMass:172]
comment	for Pentoses DeltaMass gives mass 132, for Pentosyl DeltaMass gives formula C 6 H 10 N4 with mass 146
synonym	"Pent" EXACT PSI-MOD-label []
synonym	"Pentoses (Ara, Rib, Xyl)" EXACT DeltaMass-label []
synonym	"Pentosyl" EXACT DeltaMass-label []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 5 H 8 O 4"
xref	DiffMono: "132.042259"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.730. MOD:00730 arabinosylated

Table 732. Term [MOD:00730]
id	MOD:00730
name	arabinosylated
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a arabinose sugar group through a glycosidic bond" [PubMed:18688235]
synonym	"Ara" EXACT PSI-MOD-label []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 5 H 8 O 4"
xref	DiffMono: "132.042259"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00729 pentosylated residue ! pentosylated residue

2.731. MOD:00731 ribosylated

Table 733. Term [MOD:00731]
id	MOD:00731
name	ribosylated
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a ribose sugar group through a glycosidic bond" [PubMed:18688235]
synonym	"Rib" EXACT PSI-MOD-label []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 5 H 8 O 4"
xref	DiffMono: "132.042259"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00729 pentosylated residue ! pentosylated residue

2.732. MOD:00732 xylosylated

Table 734. Term [MOD:00732]
id	MOD:00732
name	xylosylated
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a xylose sugar group through a glycosidic bond" [PubMed:18688235]
synonym	"Xyl" EXACT PSI-MOD-label []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 5 H 8 O 4"
xref	DiffMono: "132.042259"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00729 pentosylated residue ! pentosylated residue

2.733. MOD:00733 N-acetylaminoglucosylated

Table 735. Term [MOD:00733]
id	MOD:00733
name	N-acetylaminoglucosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with an N-acetylglucosamine group through a glycosidic bond." [PubMed:18688235]
synonym	"GlcNAc" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00436 N-acetylhexosaminylated ! N-acetylhexosaminylated

2.734. MOD:00734 N-acetylaminogalactosylated

Table 736. Term [MOD:00734]
id	MOD:00734
name	N-acetylaminogalactosylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with an N-acetylgalactosamine group through a glycosidic bond." [DeltaMass:247]
comment	From DeltaMass: Average Mass: 203 Formula:C8H13O5N1 Monoisotopic Mass Change:203.079 Average Mass Change:203.196 References:PE Sciex
synonym	"GalNAc" EXACT PSI-MOD-label []
synonym	"N-acetylhexosamines (GalNAc, GlcNAc)" EXACT DeltaMass-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00436 N-acetylhexosaminylated ! N-acetylhexosaminylated

2.735. MOD:00735 hexosuronylated

Table 737. Term [MOD:00735]
id	MOD:00735
name	hexosuronylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a hexosuronic acid group through a glycosidic bond." [PubMed:18688235]
synonym	"HexA" EXACT PSI-MOD-label []
xref	DiffAvg: "176.12"
xref	DiffFormula: "C 6 H 8 O 6"
xref	DiffMono: "176.032088"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.736. MOD:00736 deoxyhexosylated

Table 738. Term [MOD:00736]
id	MOD:00736
name	deoxyhexosylated
def	"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a deoxyhexose group through a glycosidic bond" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 146
subset	PSI-MOD-slim
synonym	"Deoxyhexoses (Fuc, Rha)" EXACT DeltaMass-label []
synonym	"dHex" EXACT PSI-MOD-label []
xref	DiffAvg: "146.14"
xref	DiffFormula: "C 6 H 10 O 4"
xref	DiffMono: "146.057909"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.737. MOD:00737 N-acetylneuraminylated

Table 739. Term [MOD:00737]
id	MOD:00737
name	N-acetylneuraminylated
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with an N-acetylneuraminic acid (sialic acid) group through a glycosidic bond." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 291
synonym	"N-acetylneuraminic acid (Sialic acid, NeuAc, NANA, SA)" EXACT DeltaMass-label []
synonym	"NeuNAc" EXACT PSI-MOD-label []
xref	DiffAvg: "291.26"
xref	DiffFormula: "C 11 H 17 N 1 O 8"
xref	DiffMono: "291.095417"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.738. MOD:00738 iron containing modified residue

Table 740. Term [MOD:00738]
id	MOD:00738
name	iron containing modified residue
def	"A protein modification that effectively substitutes an iron atom or a cluster containing iron for hydrogen atoms, or that coordinates an iron ion." [PubMed:18688235]
synonym	"FeRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.739. MOD:00739 iron-sulfur cluster containing modification

Table 741. Term [MOD:00739]
id	MOD:00739
name	iron-sulfur cluster containing modification
def	"A protein modification that effectively substitutes a cluster of iron and sulfur atoms for hydrogen atoms." [PubMed:18688235]
synonym	"FeSRes" EXACT PSI-MOD-label []
is_a	MOD:00738 iron containing modified residue ! iron containing modified residue
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue

2.740. MOD:00740 manganese containing modified residue

Table 742. Term [MOD:00740]
id	MOD:00740
name	manganese containing modified residue
def	"A protein modification that effectively substitutes a manganese atom or a cluster containing manganese for hydrogen atoms, or that coordinates a manganese ion." [PubMed:18688235]
synonym	"MnRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.741. MOD:00741 nickel containing modified residue

Table 743. Term [MOD:00741]
id	MOD:00741
name	nickel containing modified residue
def	"A protein modification that effectively substitutes a nickel atom or a cluster containing nickel for hydrogen atoms, or that coordinates a nickel ion." [PubMed:18688235]
synonym	"NiRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.742. MOD:00742 copper containing modified residue

Table 744. Term [MOD:00742]
id	MOD:00742
name	copper containing modified residue
def	"A protein modification that effectively substitutes a copper atom or a cluster containing copper for hydrogen atoms, or that coordinates a copper ion." [PubMed:18688235]
synonym	"CuRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.743. MOD:00743 molybdenum containing modified residue

Table 745. Term [MOD:00743]
id	MOD:00743
name	molybdenum containing modified residue
def	"A protein modification that effectively substitutes a molybdenum atom or a cluster containing molybdenum for hydrogen atoms, or that coordinates a molybdenum ion." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MoRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.744. MOD:00744 molybdenum pterin containing modification

Table 746. Term [MOD:00744]
id	MOD:00744
name	molybdenum pterin containing modification
def	"A protein modification containing a molybdenum atom in a pterin ring system." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MoPterRes" EXACT PSI-MOD-label []
is_a	MOD:00743 molybdenum containing modified residue ! molybdenum containing modified residue
is_a	MOD:00748 pterin modified residue ! pterin modified residue

2.745. MOD:00745 selenium containing residue

Table 747. Term [MOD:00745]
id	MOD:00745
name	selenium containing residue
def	"A protein modification that effectively substitutes a selenium atom or a cluster containing selenium for hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"SeRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.746. MOD:00746 tungsten containing modified residue

Table 748. Term [MOD:00746]
id	MOD:00746
name	tungsten containing modified residue
def	"A protein modification that effectively substitutes a tungsten atom or a cluster containing tungsten for hydrogen atoms, or that coordinates a tungsten ion." [PubMed:18688235]
synonym	"WRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.747. MOD:00747 sodium containing modified residue

Table 749. Term [MOD:00747]
id	MOD:00747
name	sodium containing modified residue
def	"A protein modification that effectively substitutes a sodium atom for a hydrogen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"NaRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.748. MOD:00748 pterin modified residue

Table 750. Term [MOD:00748]
id	MOD:00748
name	pterin modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a pterin group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"PterRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.749. MOD:00749 sulfur substitution for oxygen

Table 751. Term [MOD:00749]
id	MOD:00749
name	sulfur substitution for oxygen
def	"A protein modification that effectively substitutes a sulfur atom for an oxygen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"S(O)Res" EXACT PSI-MOD-label []
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue

2.750. MOD:00750 deoxyribonucleic acid linked residue

Table 752. Term [MOD:00750]
id	MOD:00750
name	deoxyribonucleic acid linked residue
def	"A protein modification that effectively crosslinks an amino acid residue and the 3'- or 5'-end of DNA through a phosphodiester bond." [PubMed:18688235]
synonym	"DNARes" EXACT PSI-MOD-label []
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.751. MOD:00751 ribonucleic acid linked residue

Table 753. Term [MOD:00751]
id	MOD:00751
name	ribonucleic acid linked residue
def	"a protein modification" [PubMed:18688235]
synonym	"RNARes" EXACT PSI-MOD-label []
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.752. MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue

Table 754. Term [MOD:00752]
id	MOD:00752
name	adenosine diphosphoribosyl (ADP-ribosyl) modified residue
def	"A protein modification that effectively results from forming an adduct with ADP-ribose through formation of a glycosidic bond." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 541.
subset	PSI-MOD-slim
synonym	"ADP-rybosylation (from NAD)" EXACT DeltaMass-label []
synonym	"ADPRibRes" EXACT PSI-MOD-label []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.753. MOD:00753 chlorinated residue

Table 755. Term [MOD:00753]
id	MOD:00753
name	chlorinated residue
def	"A protein modification that effectively substitutes a chlorine atom for a hydrogen atom." [PubMed:18688235]
synonym	"ClRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue

2.754. MOD:00754 brominated residue

Table 756. Term [MOD:00754]
id	MOD:00754
name	brominated residue
def	"A protein modification that effectively substitutes a bromine atom for a hydrogen atom." [PubMed:18688235]
synonym	"BrRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue

2.755. MOD:00755 iodinated residue

Table 757. Term [MOD:00755]
id	MOD:00755
name	iodinated residue
def	"A protein modification that effectively substitutes an iodine atom of a residue for a hydrogen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"IRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue

2.756. MOD:00756 4-hydroxy-D-valine

Table 758. Term [MOD:00756]
id	MOD:00756
name	4-hydroxy-D-valine
def	"A protein modification that effectively converts an L-valine residue to 4-hydroxy-D-valine." [PubMed:15853325, RESID:AA0388]
synonym	"(2R,3Xi)-2-amino-4-hydroxy-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"4-hydroxy-D-valine" EXACT RESID-name []
synonym	"D-4HyVal" EXACT PSI-MOD-label []
synonym	"D-gamma-hydroxyvaline" EXACT RESID-alternate []
synonym	"MOD_RES D-4-hydroxyvaline" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2"
xref	MassAvg: "115.13"
xref	MassMono: "115.063329"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue

2.757. MOD:00757 O4-galactosyl-L-hydroxyproline

Table 759. Term [MOD:00757]
id	MOD:00757
name	O4-galactosyl-L-hydroxyproline
def	"A protein modification that effectively converts an L-proline residue to O4-galactosyl-L-hydroxyproline." [RESID:AA0389]
comment	secondary to RESID:AA0030
synonym	"(2S,4R)-4-(beta-D-galactopyranosyloxy)pyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"4-(beta-D-galactopyranosyloxy)proline" EXACT RESID-alternate []
synonym	"4-(galactosyloxy)proline" EXACT RESID-alternate []
synonym	"beta-galactopyranosyl-4-hydroxyproline" EXACT RESID-alternate []
synonym	"O4-galactosyl-L-hydroxyproline" EXACT RESID-name []
synonym	"O4-glycosyl-hydroxyproline" EXACT RESID-alternate []
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 N 0 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "C 11 H 17 N 1 O 7"
xref	MassAvg: "275.26"
xref	MassMono: "275.100502"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.758. MOD:00758 O4-(N-acetylamino)glucosyl-L-hydroxyproline

Table 760. Term [MOD:00758]
id	MOD:00758
name	O4-(N-acetylamino)glucosyl-L-hydroxyproline
def	"A protein modification that effectively converts an L-proline residue to O4-(N-acetylamino)glucosyl-L-hydroxyproline." [PubMed:15238247, PubMed:9660787, RESID:AA0390]
comment	secondary to RESID:AA0030
synonym	"(2S,4R)-4-[2-acetamido-2-deoxy-alpha-D-glucopyranosyloxy]pyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"4-(N-acetylglucosaminyloxy)proline" EXACT RESID-alternate []
synonym	"4-[(2-N-acetylamino)-alpha-D-glucopyranosyl]oxyproline" EXACT RESID-alternate []
synonym	"alpha-2-(N-acetylamino)glucopyranosyl-4-hydroxyproline" EXACT RESID-alternate []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"O4-(N-acetylamino)glucosyl-L-hydroxyproline" EXACT RESID-name []
synonym	"O4-glycosyl-hydroxyproline" EXACT RESID-alternate []
synonym	"O4GlcNAcHyPro" EXACT PSI-MOD-label []
xref	DiffAvg: "219.19"
xref	DiffFormula: "C 8 H 13 N 1 O 6"
xref	DiffMono: "219.074287"
xref	Formula: "C 13 H 20 N 2 O 7"
xref	MassAvg: "316.31"
xref	MassMono: "316.127051"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:01677 O4-(N-acetylamino)hexosyl-L-hydroxyproline ! O4-(N-acetylamino)hexosyl-L-hydroxyproline

2.759. MOD:00759 fucosylated biantennary (-1 galactose)

Table 761. Term [MOD:00759]
id	MOD:00759
name	fucosylated biantennary (-1 galactose)
def	"modification from UniMod N-linked glycosylation" [UniMod:307]
synonym	"dHex(1)Hex(4)HexNAc(4)" RELATED PSI-MS-label []
synonym	"Fucosylated biantennary (-1 galactose)" RELATED UniMod-description []
xref	DiffAvg: "1607.48"
xref	DiffFormula: "C 62 H 102 N 4 O 44"
xref	DiffMono: "1606.586693"
xref	Formula: "C 66 H 108 N 6 O 46"
xref	MassAvg: "1721.59"
xref	MassMono: "1720.629620"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.760. MOD:00760 biantennary

Table 762. Term [MOD:00760]
id	MOD:00760
name	biantennary
def	"modification from UniMod N-linked glycosylation - missing ref" [UniMod:311]
synonym	"Biantennary" RELATED UniMod-description []
synonym	"Hex(5)HexNAc(4)" RELATED PSI-MS-label []
xref	DiffAvg: "1623.48"
xref	DiffFormula: "C 62 H 102 N 4 O 45"
xref	DiffMono: "1622.581607"
xref	Formula: "C 66 H 108 N 6 O 47"
xref	MassAvg: "1737.59"
xref	MassMono: "1736.624535"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.761. MOD:00761 monohexosylated (Hex1)

Table 763. Term [MOD:00761]
id	MOD:00761
name	monohexosylated (Hex1)
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with one hexose sugar group through a glycosidic bond." [PubMed:18688235]
synonym	"Hex1" EXACT PSI-MOD-alternate []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00434 hexosylated residue ! hexosylated residue

2.762. MOD:00762 biantennary (-2 galactose)

Table 764. Term [MOD:00762]
id	MOD:00762
name	biantennary (-2 galactose)
def	"modification from UniMod N-linked glycosylation - missing ref" [UniMod:309]
synonym	"Biantennary (-2 galactose)" RELATED UniMod-description []
synonym	"Hex(3)HexNAc(4)" RELATED PSI-MS-label []
xref	DiffAvg: "1299.20"
xref	DiffFormula: "C 50 H 82 N 4 O 35"
xref	DiffMono: "1298.475960"
xref	Formula: "C 54 H 88 N 6 O 37"
xref	MassAvg: "1413.30"
xref	MassMono: "1412.518888"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.763. MOD:00763 biantennary (-1 galactose)

Table 765. Term [MOD:00763]
id	MOD:00763
name	biantennary (-1 galactose)
def	"modification from UniMod N-linked glycosylation - missing ref" [UniMod:310]
synonym	"Biantennary (-1 galactose)" RELATED UniMod-description []
synonym	"Hex(4)HexNAc(4)" RELATED PSI-MS-label []
xref	DiffAvg: "1461.34"
xref	DiffFormula: "C 56 H 92 N 4 O 40"
xref	DiffMono: "1460.528784"
xref	Formula: "C 60 H 98 N 6 O 42"
xref	MassAvg: "1575.44"
xref	MassMono: "1574.571711"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.764. MOD:00764 glycoconjugated residue

Table 766. Term [MOD:00764]
id	MOD:00764
name	glycoconjugated residue
def	"A protein modification that effectively results from forming an adduct with a carbohydrate-like group either through enzymatic formation of a glycosidic bond, or through non-enzymatic glycation formation of a Schiff-base or an Amadori ketosamine residue adduct." [PubMed:18688235, PubMed:3743566]
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.765. MOD:00765 cysteinylation (disulfide with free L-cysteine)

Table 767. Term [MOD:00765]
id	MOD:00765
name	cysteinylation (disulfide with free L-cysteine)
def	"A protein modification that effectively converts an L-cysteine residue to S-(L-cysteinyl)-L-cysteine, forming a disulfide bond with free cysteine." [DeltaMass:260, PubMed:1988019, PubMed:2001356, PubMed:2076469, PubMed:3083866, PubMed:366603, PubMed:7918467, PubMed:8344916, RESID:AA0025#CYS1, UniMod:312]
comment	This entry is for formation of a disulfide bond between a peptide cysteine and a free cysteine. For the cystine cross-link, see MOD:00234. From DeltaMass: (name misspelled and formula incorrect, N and O reversed) Formula: C6H10O2N3S2 Monoisotopic Mass Change: 222.013 Average Mass Change: 222.283
subset	PSI-MOD-slim
synonym	"(2R,2’R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid" RELATED RESID-misnomer []
synonym	"3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobisalanine" EXACT RESID-alternate []
synonym	"3,3'-dithiodialanine" EXACT RESID-alternate []
synonym	"beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide" EXACT RESID-alternate []
synonym	"beta,beta'-dithiodialanine" EXACT RESID-alternate []
synonym	"bis(alpha-aminopropionic acid)-beta-disulfide" EXACT RESID-alternate []
synonym	"bis(beta-amino-beta-carboxyethyl)disulfide" EXACT RESID-alternate []
synonym	"Cysteinylation" EXACT DeltaMass-label []
synonym	"dicysteine" EXACT RESID-alternate []
synonym	"L-cystine" EXACT RESID-name []
synonym	"MOD_RES S-cysteinyl cysteine" EXACT UniProt-feature []
synonym	"S-cystenyl cystenyl" EXACT DeltaMass-label []
synonym	"SCysCys" EXACT PSI-MOD-label []
xref	DiffAvg: "119.14"
xref	DiffFormula: "C 3 H 5 N 1 O 2 S 1"
xref	DiffMono: "119.004099"
xref	Formula: "C 6 H 10 N 2 O 3 S 2"
xref	MassAvg: "222.28"
xref	MassMono: "222.013284"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.766. MOD:00766 C terminal -K from HC of MAb

Table 768. Term [MOD:00766]
id	MOD:00766
name	C terminal -K from HC of MAb
def	"modification from UniMod Post-translational - C-terminal loss of lysine" [PubMed:16078144, UniMod:313]
synonym	"Loss of C-terminal K from Heavy Chain of MAb" RELATED UniMod-description []
synonym	"Lys-loss" RELATED PSI-MS-label []
xref	DiffAvg: "-128.18"
xref	DiffFormula: "C -6 H -12 N -2 O -1"
xref	DiffMono: "-128.094963"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	TermSpec: "C-term"
is_a	MOD:00003 UniMod ! UniMod

2.767. MOD:00767 glycated residue

Table 769. Term [MOD:00767]
id	MOD:00767
name	glycated residue
def	"A modification produced in a non-enzymatic reaction between a carbohydrate carbonyl group (C1 of aldohexose or C2 of fructose) and a protein amino group to form a Schiff-base or an Amadori ketosamine residue adduct." [PubMed:18688235]
xref	Source: "artifact"
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue

2.768. MOD:00768 methionine oxidation with neutral loss of 80 Da

Table 770. Term [MOD:00768]
id	MOD:00768
name	methionine oxidation with neutral loss of 80 Da
def	"Oxidation of methionine to methionine sulfone with neutral loss of CH3SO2H." [PubMed:18688235, PubMed:9004526]
comment	Originally created from UniMod:508 that was later deleted.
xref	DiffAvg: "-80.10"
xref	DiffFormula: "C -1 H -4 N 0 O -2 S -1"
xref	DiffMono: "-79.993200"
xref	Formula: "C 4 H 5 N 1 O 1 S 0"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss

2.769. MOD:00769 residues isobaric at 71.0-71.1 Da

Table 771. Term [MOD:00769]
id	MOD:00769
name	residues isobaric at 71.0-71.1 Da
def	"Natural or modified residues with a mass of 71.0-71.1 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00616 residues isobaric at a resolution below 0.1 Da ! residues isobaric at a resolution below 0.1 Da

2.770. MOD:00770 residues isobaric at a resolution below 0.01 Da

Table 772. Term [MOD:00770]
id	MOD:00770
name	residues isobaric at a resolution below 0.01 Da
def	"Natural or modified residues that are isobaric at a resolution below 0.01 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00616 residues isobaric at a resolution below 0.1 Da ! residues isobaric at a resolution below 0.1 Da

2.771. MOD:00771 residues isobaric at 166.98-167.00 Da

Table 773. Term [MOD:00771]
id	MOD:00771
name	residues isobaric at 166.98-167.00 Da
def	"Natural or modified residues with a mass of 166.98-167.00 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00770 residues isobaric at a resolution below 0.01 Da ! residues isobaric at a resolution below 0.01 Da

2.772. MOD:00772 vanadium containing modified residue

Table 774. Term [MOD:00772]
id	MOD:00772
name	vanadium containing modified residue
def	"A protein modification that effectively substitutes a vanadium atom or a cluster containing vanadium for hydrogen atoms, or that coordinates a vanadium ion." [PubMed:18688235]
synonym	"VRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.773. MOD:00773 residues isobaric at 181.00-181.02 Da

Table 775. Term [MOD:00773]
id	MOD:00773
name	residues isobaric at 181.00-181.02 Da
def	"Natural or modified residues with a mass of 181.00-181.02 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00770 residues isobaric at a resolution below 0.01 Da ! residues isobaric at a resolution below 0.01 Da

2.774. MOD:00774 residues isobaric at 243.02-243.03 Da

Table 776. Term [MOD:00774]
id	MOD:00774
name	residues isobaric at 243.02-243.03 Da
def	"Natural or modified residues with a mass of 243.02-243.03 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00770 residues isobaric at a resolution below 0.01 Da ! residues isobaric at a resolution below 0.01 Da

2.775. MOD:00775 L-asparagine (His)

Table 777. Term [MOD:00775]
id	MOD:00775
name	L-asparagine (His)
def	"An artifactual protein modification that converts an L-histidine residue to L-asparagine by oxidative degradation." [OMSSA:54, PubMed:9252331, UniMod:348]
synonym	"His→Asn" RELATED PSI-MS-label []
synonym	"his2asnh" EXACT OMSSA-label []
synonym	"histidine oxidation to aspargine" RELATED UniMod-description []
xref	DiffAvg: "-23.04"
xref	DiffFormula: "C -2 H -1 N -1 O 1"
xref	DiffMono: "-23.015984"
xref	Formula: "C 4 H 6 N 2 O 2"
xref	MassAvg: "114.10"
xref	MassMono: "114.042927"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00012 L-asparagine residue ! L-asparagine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.776. MOD:00776 L-aspartic acid (His)

Table 778. Term [MOD:00776]
id	MOD:00776
name	L-aspartic acid (His)
def	"An artifactual protein modification that converts an L-histidine residue to L-aspartic acid by oxidative degradation." [OMSSA:55, PubMed:9252331, UniMod:349]
comment	From OMSSA: desc="oxidation of H to D" monomass= -23.015984 (this is the same mass difference as OMSSA:54, his2asnh) [JSG].
synonym	"His→Asp" RELATED PSI-MS-label []
synonym	"his2asph" EXACT OMSSA-label []
synonym	"histidine oxidation to aspartic acid" RELATED UniMod-description []
xref	DiffAvg: "-22.05"
xref	DiffFormula: "C -2 H -2 N -2 O 2"
xref	DiffMono: "-22.031969"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00013 L-aspartic acid residue ! L-aspartic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.777. MOD:00777 residues isobaric at 182.96-182.98 Da

Table 779. Term [MOD:00777]
id	MOD:00777
name	residues isobaric at 182.96-182.98 Da
def	"Natural or modified residues with a mass of 182.96-182.98 Da." [PubMed:18688235]
is_a	MOD:00770 residues isobaric at a resolution below 0.01 Da ! residues isobaric at a resolution below 0.01 Da
is_a	MOD:00778 residues isobaric at 182.9-183.0 Da ! residues isobaric at 182.9-183.0 Da

2.778. MOD:00778 residues isobaric at 182.9-183.0 Da

Table 780. Term [MOD:00778]
id	MOD:00778
name	residues isobaric at 182.9-183.0 Da
def	"Natural or modified residues with a mass of 182.9-183.0 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00616 residues isobaric at a resolution below 0.1 Da ! residues isobaric at a resolution below 0.1 Da

2.779. MOD:00779 lysine oxidation to aminoadipic semialdehyde

Table 781. Term [MOD:00779]
id	MOD:00779
name	lysine oxidation to aminoadipic semialdehyde
def	"OBSOLETE because redundant with MOD:00130. Remap to MOD:00130." [DeltaMass:352, PubMed:11332453, PubMed:358196, PubMed:5337886, PubMed:5529814, UniMod:352]
comment	From DeltaMass: Average Mass: -1 Average Mass Change:-1 References:Amici A, Levine, RL, Tsai, L, and Stadtman, ER: Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions. Journal of Biological Chemistry 264: 3341-3346 1989.Requena JR, Chao CC, Levine RL, and Stadtman ER: Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins. Proceedings of the National Academy of Sciences USA 98: 69-74 2001.
synonym	"Oxidation of lysine (to aminoadipic semialdehyde)" EXACT DeltaMass-label []
xref	DiffAvg: "-1.03"
xref	DiffFormula: "H -3 N -1 O 1"
xref	DiffMono: "-1.031634"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.780. MOD:00780 N-acetyl-L-asparagine

Table 782. Term [MOD:00780]
id	MOD:00780
name	N-acetyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N-acetyl-L-asparagine." [PubMed:18688235]
comment	This modification has not been observed to occur naturally.
synonym	"AcAsn" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 6 H 8 N 2 O 3"
xref	MassAvg: "156.14"
xref	MassMono: "156.053492"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.781. MOD:00781 N2-acetyl-L-histidine

Table 783. Term [MOD:00781]
id	MOD:00781
name	N2-acetyl-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to N2-acetyl-L-histidine." [PubMed:18688235]
comment	This modification has not been observed to occur naturally.
synonym	"AcHis" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 9 N 3 O 2"
xref	MassAvg: "179.18"
xref	MassMono: "179.069477"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.782. MOD:00782 N-acetyl-L-leucine

Table 784. Term [MOD:00782]
id	MOD:00782
name	N-acetyl-L-leucine
def	"A protein modification that effectively converts an L-leucine residue to N-acetyl-L-leucine." [PubMed:18688235]
comment	This modification has not been observed to occur naturally.
synonym	"AcLeu" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 8 H 14 N 1 O 2"
xref	MassAvg: "156.20"
xref	MassMono: "156.102454"
xref	Origin: "L"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.783. MOD:00783 dimethylated L-arginine

Table 785. Term [MOD:00783]
id	MOD:00783
name	dimethylated L-arginine
def	"A protein modification that effectively replaces two hydrogen atoms of an L-arginine residue with two methyl groups." [OMSSA:37, UniMod:36#R]
subset	PSI-MOD-slim
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"dimethylr" EXACT OMSSA-label []
synonym	"NNMe2Arg" EXACT PSI-MOD-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 4 O 1"
xref	MassAvg: "184.24"
xref	MassMono: "184.132411"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00429 dimethylated residue ! dimethylated residue
is_a	MOD:00658 methylated arginine ! methylated arginine

2.784. MOD:00784 N-acetyl-L-phenylalanine

Table 786. Term [MOD:00784]
id	MOD:00784
name	N-acetyl-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to N-acetyl-L-phenylalanine." [PubMed:18688235]
comment	This modification has not been observed to occur naturally.
synonym	"AcPhe" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 11 H 11 N 1 O 2"
xref	MassAvg: "189.21"
xref	MassMono: "189.078979"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.785. MOD:00785 N2-acetyl-L-tryptophan

Table 787. Term [MOD:00785]
id	MOD:00785
name	N2-acetyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N2-acetyl-L-tryptophan." [PubMed:18688235]
comment	This modification has not been observed to occur naturally.
synonym	"AcTrp" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 13 H 12 N 2 O 2"
xref	MassAvg: "228.25"
xref	MassMono: "228.089878"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:01458 alpha-amino acetylated residue ! alpha-amino acetylated residue

2.786. MOD:00786 deuterium substituted residue

Table 788. Term [MOD:00786]
id	MOD:00786
name	deuterium substituted residue
def	"A protein modification that effectively substitutes one or more (2)H deuterium atoms for (1)H protium atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"D(H)Res" EXACT PSI-MOD-label []
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue

2.787. MOD:00787 diisopropylphosphoserine

Table 789. Term [MOD:00787]
id	MOD:00787
name	diisopropylphosphoserine
def	"modification from UniMod - label for the active site serine of the serine esterase/protease family also shown to label tyrosine in serum albumin" [UniMod:362]
synonym	"Diisopropylphosphate" RELATED UniMod-interim []
synonym	"O-Diisopropylphosphorylation" RELATED UniMod-description []
xref	DiffAvg: "164.14"
xref	DiffFormula: "C 6 H 13 O 3 P 1"
xref	DiffMono: "164.060231"
xref	Formula: "C 9 H 18 N 1 O 5 P 1"
xref	MassAvg: "251.22"
xref	MassMono: "251.092259"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.788. MOD:00788 isopropylphosphotyrosine

Table 790. Term [MOD:00788]
id	MOD:00788
name	isopropylphosphotyrosine
def	"modification from UniMod" [UniMod:363]
synonym	"Isopropylphospho" RELATED UniMod-interim []
synonym	"O-Isopropylphosphorylation" RELATED UniMod-description []
xref	DiffAvg: "122.06"
xref	DiffFormula: "C 3 H 7 O 3 P 1"
xref	DiffMono: "122.013281"
xref	Formula: "C 12 H 16 N 1 O 5 P 1"
xref	MassAvg: "285.24"
xref	MassMono: "285.076609"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.789. MOD:00789 Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form

Table 791. Term [MOD:00789]
id	MOD:00789
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form
def	"modification from UniMod - isotopic label ICPL method - The paper describes an H/D labeling strategy whereas the commercial product follows a C/13C labeling strategy. The digest is typically applied AFTER ICPL_light/heavy labeling, only Protein N-term labeling and Lys-specific labeling is applied." [PubMed:15602776, UniMod:364, URL:http\://www.serva.de/products/sheets/39230-E.pdf]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form" RELATED UniMod-description []
synonym	"ICPL:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "111.04"
xref	DiffFormula: "(13)C 6 H 3 N 1 O 1"
xref	DiffMono: "111.041593"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.790. MOD:00790 Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form

Table 792. Term [MOD:00790]
id	MOD:00790
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form
def	"modification from UniMod - isotopic label ICPL method - The paper describes an H/D labeling strategy whereas the commercial product follows a C/13C labeling strategy. The digest is typically applied AFTER ICPL_light/heavy labeling, only Protein N-term labeling and Lys-specific labeling is applied." [PubMed:15602776, UniMod:365, URL:http\://www.serva.de/products/sheets/39230-E.pdf]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form" RELATED UniMod-description []
synonym	"ICPL" RELATED PSI-MS-label []
xref	DiffAvg: "105.02"
xref	DiffFormula: "(12)C 6 H 3 N 1 O 1"
xref	DiffMono: "105.021464"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.791. MOD:00791 1x(18)O labeled deamidated L-glutamine

Table 793. Term [MOD:00791]
id	MOD:00791
name	1x(18)O labeled deamidated L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to L-glutamic acid with one (18)O." [PubMed:8382902, UniMod:366#Q]
subset	PSI-MOD-slim
synonym	"Deamidated:18O(1)" RELATED PSI-MS-label []
synonym	"Deamidation in presence of O18" RELATED UniMod-description []
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "C 5 H 7 N 1 (16)O 2 (18)O 1"
xref	MassAvg: "131.05"
xref	MassMono: "131.046839"
xref	Origin: "Q"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00685 deamidated L-glutamine ! deamidated L-glutamine
is_a	MOD:00852 1x(18)O labeled deamidated residue ! 1x(18)O labeled deamidated residue

2.792. MOD:00792 deuterium monosubstituted residue

Table 794. Term [MOD:00792]
id	MOD:00792
name	deuterium monosubstituted residue
def	"A protein modification that effectively substitutes one (2)H deuterium atom for one (1)H protium atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"D(H)1Res" EXACT PSI-MOD-label []
is_a	MOD:00786 deuterium substituted residue ! deuterium substituted residue

2.793. MOD:00793 dehydroalanine (Cys)

Table 795. Term [MOD:00793]
id	MOD:00793
name	dehydroalanine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to dehydroalanine." [ChEBI:17123, DeltaMass:8, PubMed:10220322, PubMed:11212008, PubMed:1547888, PubMed:15799070, PubMed:1815586, PubMed:20805503, PubMed:2914619, PubMed:7947813, PubMed:8239649, RESID:AA0181#CYS, UniMod:368]
comment	From DeltaMass: In an attempt to clarfiy the difference between the modification of cysteine to lanthionine and cysteine to dehydroalanine, the following contributions from the ABRF email forum are presented:Structurally speaking lanthionine is like cystine but lacks one S atom. I imagine one can think of it as a condensation of cysteine and dehydroalanine but I do not know how it is made biologically. Dehydroalanine could be derived from either serine or cysteine. If I recall Biochem 101 correctly lanthionine was first found in wool.-Lowell Ericsson (ERICSSONLH@U.WASHINGTON.EDU)As far as I know, the structure of lanthionine is two Ala’s joined by a single sulphur with the loss of two hydrogens from the methyl group of the Ala.Stephen Bayne (sbay@novo.dk)Regarding the structure of lanthionine and dehydroalanine: dehydroalanine is formed by the loss of one sulfur atom and two hydrogen atoms from ONE cysteine residue. lanthionine is formed from TWO cysteines, is a thioether, and contains one sulfur atom less than the amino acid cystine. Dan McCormick (MCCORMICK@rcf.mayo.edu) [DeltaMass]. Most bacterially produced lanthionine crosslinks are made by dehydration of L-serine to dehydroalanine, and then reaction with L-cysteine so as to produce chiral inversion at the alpha-carbon of the original L-serine; the lanthionine is a meso-diastereomer with L-configuration of the original cysteine alpha-carbon and D-configuration of the original L-serine alpha-carbon. In cypemycin dehydroalanine has been shown to be produced by loss of hydrogen sulfide from cysteine. Beta-elimination of hydrogen sulfide does occur during treatment with performic acid [JSG].
subset	PSI-MOD-slim
synonym	"2,3-didehydroalanine" EXACT RESID-alternate []
synonym	"2-aminoacrylic acid" EXACT RESID-alternate []
synonym	"2-aminopropenoic acid" EXACT RESID-systematic []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"anhydroserine" EXACT RESID-alternate []
synonym	"Cys→Dha" RELATED PSI-MS-label []
synonym	"dehydroalanine" EXACT RESID-name []
synonym	"Dehydroalanine (from Cysteine)" EXACT DeltaMass-label []
synonym	"Dehydroalanine (from Cysteine)" RELATED UniMod-description []
synonym	"Dha" EXACT RESID-alternate []
synonym	"dHAla(Cys)" EXACT PSI-MOD-label []
synonym	"MOD_RES 2,3-didehydroalanine (Cys)" EXACT UniProt-feature []
xref	DiffAvg: "-34.08"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S -1"
xref	DiffMono: "-33.987721"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01168 dehydroalanine ! dehydroalanine

2.794. MOD:00794 pyrrolidone from proline

Table 796. Term [MOD:00794]
id	MOD:00794
name	pyrrolidone from proline
def	"OBSOLETE because redundant and identical to MOD:00477. Remap to MOD:00477." [PubMed:9252331, UniMod:369]
comment	This UniMod entry appears to have come from the same description in PubMed:9252331 as UniMod:360. This entry was not annotated as being approved. Neither difference formula corresponds to the result described in the original citation PubMed:2161657.
synonym	"Pro→Pyrrolidone" RELATED UniMod-interim []
synonym	"Pyrrolidone from Proline" RELATED UniMod-description []
xref	DiffAvg: "-28.01"
xref	DiffFormula: "C -1 O -1"
xref	DiffMono: "-27.994915"
xref	Formula: "C 4 H 7 N 1 O 0"
xref	MassAvg: "69.11"
xref	MassMono: "69.057849"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.795. MOD:00795 Michael addition of hydroxymethylvinyl ketone to cysteine

Table 797. Term [MOD:00795]
id	MOD:00795
name	Michael addition of hydroxymethylvinyl ketone to cysteine
def	"modification from UniMod" [PubMed:11743741, UniMod:371]
synonym	"HMVK" RELATED PSI-MS-label []
synonym	"Michael addition of hydroxymethylvinyl ketone to cysteine" RELATED UniMod-description []
xref	DiffAvg: "86.09"
xref	DiffFormula: "C 4 H 6 O 2"
xref	DiffMono: "86.036779"
xref	Formula: "C 7 H 11 N 1 O 3 S 1"
xref	MassAvg: "189.23"
xref	MassMono: "189.045964"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.796. MOD:00796 L-ornithine (Arg)

Table 798. Term [MOD:00796]
id	MOD:00796
name	L-ornithine (Arg)
def	"A protein modification that effectively converts an L-arginine residue to L-ornithine." [DeltaMass:129, OMSSA:163, PubMed:15489230, UniMod:372]
subset	PSI-MOD-slim
synonym	"Arg→Orn" RELATED PSI-MS-label []
synonym	"arg2orn" EXACT OMSSA-label []
synonym	"Ornithine (from Arginine)" EXACT DeltaMass-label []
synonym	"Ornithine from Arginine" RELATED UniMod-description []
synonym	"Ornithyl" EXACT DeltaMass-label []
xref	DiffAvg: "-42.04"
xref	DiffFormula: "C -1 H -2 N -2"
xref	DiffMono: "-42.021798"
xref	Formula: "C 5 H 10 N 2 O 1"
xref	MassAvg: "114.15"
xref	MassMono: "114.079313"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.797. MOD:00797 2-(S-L-cysteinyl)pyruvic acid O-phosphothioketal

Table 799. Term [MOD:00797]
id	MOD:00797
name	2-(S-L-cysteinyl)pyruvic acid O-phosphothioketal
def	"a protein modification that effectively converts an L-cysteine residue to the PEP adduct, 2-(S-L-cysteinyl)pyruvic acid O-phosphothioketal" [PubMed:4696757, PubMed:7999765, PubMed:8664284, RESID:AA0391]
synonym	"(2R)-2-amino-3-[1-carboxy-1-(phosphonooxy)ethyl]sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-2-(phosphonooxy)propanoic acid" EXACT RESID-alternate []
synonym	"2-([(2R)-2-azanyl-2-carboxyethyl]sulfanyl)-2-(phosphonooxy)propanoic acid" EXACT RESID-alternate []
synonym	"2-(S-L-cysteinyl)pyruvic acid O-phosphothioketal" EXACT RESID-name []
synonym	"cysteinyl pyruvate O-phosphothioketal" EXACT RESID-alternate []
synonym	"MOD_RES 2-(S-cysteinyl)pyruvic acid O-phosphothioketal" EXACT UniProt-feature []
synonym	"phosphoenolpyruvate cysteine adduct" EXACT RESID-alternate []
synonym	"phospholactoyl cysteine adduct" EXACT RESID-alternate []
synonym	"S-[1-carboxy-1-(phosphonooxy)ethyl]cysteine" EXACT RESID-alternate []
synonym	"SPEPCys" EXACT PSI-MOD-label []
xref	DiffAvg: "168.04"
xref	DiffFormula: "C 3 H 5 N 0 O 6 P 1 S 0"
xref	DiffMono: "167.982375"
xref	Formula: "C 6 H 10 N 1 O 7 P 1 S 1"
xref	MassAvg: "271.18"
xref	MassMono: "270.991559"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.798. MOD:00798 half cystine

Table 800. Term [MOD:00798]
id	MOD:00798
name	half cystine
def	"A protein modification that can be regarded as effectively either one half of a cystine cross-link, or a cysteine residue with one hydrogen atom or proton removed." [PubMed:1988019, PubMed:2001356, PubMed:2076469, PubMed:3083866, PubMed:366603, PubMed:7918467, PubMed:8344916, UniMod:374]
synonym	"Dehydro" RELATED PSI-MS-label []
synonym	"Half of a disulfide bridge" RELATED UniMod-description []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0 S 0"
xref	DiffMono: "-1.007825"
xref	Formula: "C 3 H 4 N 1 O 1 S 1"
xref	MassAvg: "102.13"
xref	MassMono: "102.001360"
xref	Origin: "C"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.799. MOD:00799 S-galactosyl-L-cysteine

Table 801. Term [MOD:00799]
id	MOD:00799
name	S-galactosyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-galactosyl-L-cysteine." [PubMed:11945907, RESID:AA0392]
comment	The reported peptide has not been isolated or characterized in subsequent work, and the peptide sequence has not been found in the human proteome. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2R)-2-amino-3-(D-galactopyranosylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"S-(beta-D-galactopyranosyl)cysteine" EXACT RESID-alternate []
synonym	"S-galactosyl-L-cysteine" EXACT RESID-name []
synonym	"S-glycosyl-cysteine" EXACT RESID-alternate []
synonym	"SGalCys" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5 S 0"
xref	DiffMono: "162.052823"
xref	Formula: "C 9 H 15 N 1 O 6 S 1"
xref	MassAvg: "265.28"
xref	MassMono: "265.062008"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00426 S-glycosylated residue ! S-glycosylated residue
is_a	MOD:00476 galactosylated residue ! galactosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.800. MOD:00800 L-cysteinyl-L-histidino-homocitryl vanadium heptairon nonasulfide

Table 802. Term [MOD:00800]
id	MOD:00800
name	L-cysteinyl-L-histidino-homocitryl vanadium heptairon nonasulfide
def	"A protein modification that effectively converts an L-cysteine residue, an L-histidine residue, homocitric acid and a one-vanadium seven-iron nine-sulfur cluster to L-cysteinyl-L-histidino-homocitryl vanadium heptairon nonasulfide." [PubMed:2345152, RESID:AA0393]
comment	Cross-link 2; incidental to RESID:AA0300.
synonym	"CysHis-[V7Fe9S]" EXACT PSI-MOD-label []
synonym	"L-cysteinyl-L-histidino-homocitryl vanadium heptairon nonasulfide carbide" EXACT RESID-name []
synonym	"nitrogenase iron-vanadium cofactor" EXACT RESID-alternate []
xref	DiffAvg: "932.51"
xref	DiffFormula: "C 7 Fe 7 H 6 N 0 O 7 S 9 V 1"
xref	DiffMono: "932.248513"
xref	Formula: "C 16 Fe 7 H 18 N 4 O 9 S 10 V 1"
xref	MassAvg: "1172.80"
xref	MassMono: "1172.316610"
xref	Origin: "C, H"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00772 vanadium containing modified residue ! vanadium containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.801. MOD:00801 L-cysteinyl-L-histidino-homocitryl octairon nonasulfide

Table 803. Term [MOD:00801]
id	MOD:00801
name	L-cysteinyl-L-histidino-homocitryl octairon nonasulfide
def	"A protein modification that effectively converts an L-cysteine residue, an L-histidine residue, homocitric acid and an eight-iron nine-sulfur cluster to L-cysteinyl-L-histidino-homocitryl octairon nonasulfide." [PubMed:8392330, RESID:AA0394]
comment	Cross-link 2; incidental to RESID:AA0300.
synonym	"CysHis-[8Fe9S]" EXACT PSI-MOD-label []
synonym	"L-cysteinyl-L-histidino-homocitryl octairon nonasulfide carbide" EXACT RESID-name []
synonym	"nitrogenase iron-iron cofactor" EXACT RESID-alternate []
xref	DiffAvg: "937.42"
xref	DiffFormula: "C 7 Fe 8 H 6 N 0 O 7 S 9"
xref	DiffMono: "937.240588"
xref	FormalCharge: "2-"
xref	Formula: "C 16 Fe 8 H 18 N 4 O 9 S 10"
xref	MassAvg: "1177.70"
xref	MassMono: "1177.308685"
xref	Origin: "C, H"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.802. MOD:00802 L-histidino vanadium tetraoxide

Table 804. Term [MOD:00802]
id	MOD:00802
name	L-histidino vanadium tetraoxide
def	"a protein modification that effectively converts an L-histidine residue to L-histidino vanadium tetraoxide" [PubMed:10543953, PubMed:16494433, PubMed:8552646, RESID:AA0395]
synonym	"(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl) (dihydroxy)dioxovanadium" EXACT RESID-alternate []
synonym	"1'-vanadato-L-histidine" EXACT RESID-alternate []
synonym	"bromoperoxidase vanadium cofactor" EXACT RESID-alternate []
synonym	"chloroperoxidase vanadium cofactor" EXACT RESID-alternate []
synonym	"dihydrogen (4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl) (tetraoxido)vanadate" EXACT RESID-systematic []
synonym	"haloperoxidase vanadium cofactor" EXACT RESID-alternate []
synonym	"histidine-1-vanadate" EXACT RESID-alternate []
synonym	"histidine-N(epsilon)-vanadate" EXACT RESID-alternate []
synonym	"histidine-N1'-vanadate" EXACT RESID-alternate []
synonym	"L-histidino vanadium tetraoxide" EXACT RESID-name []
synonym	"N(tau)-vanadatohistidine" EXACT RESID-alternate []
synonym	"NtauH2VO4His" EXACT PSI-MOD-label []
synonym	"tele-vanadatohistidine" EXACT RESID-alternate []
xref	DiffAvg: "116.95"
xref	DiffFormula: "C 0 H 2 N 0 O 4 V 1"
xref	DiffMono: "116.939268"
xref	Formula: "C 6 H 9 N 3 O 5 V 1"
xref	MassAvg: "254.10"
xref	MassMono: "253.998180"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00772 vanadium containing modified residue ! vanadium containing modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.803. MOD:00803 3-(S-L-cysteinyl)-L-tyrosine

Table 805. Term [MOD:00803]
id	MOD:00803
name	3-(S-L-cysteinyl)-L-tyrosine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 3-(S-L-cysteinyl)-L-tyrosine." [PubMed:15342250, RESID:AA0396]
comment	Cross-link 2.
synonym	"(2S,3R)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-(4-hydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(2-amino-2-carboxyethylthio)-3-(4-hydroxyphenyl)propanoic acid" EXACT RESID-alternate []
synonym	"3-(L-cystein-S-yl)-L-tyrosine" EXACT RESID-name []
synonym	"CROSSLNK 3-(S-cysteinyl)-tyrosine (Cys-Tyr)" EXACT UniProt-feature []
synonym	"S-(tyros-3'-yl)cysteine" EXACT RESID-alternate []
synonym	"XLNKSCys3Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 3 S 1"
xref	MassAvg: "264.30"
xref	MassMono: "264.056863"
xref	Origin: "C, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues

2.804. MOD:00804 O-glucosyl-L-serine

Table 806. Term [MOD:00804]
id	MOD:00804
name	O-glucosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine." [PubMed:10734111, PubMed:2105311, PubMed:2511201, RESID:AA0397]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(beta-D-glucopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (Glc)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Hex)" EXACT UniProt-feature []
synonym	"O-glucosyl-L-serine" EXACT RESID-name []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O3-glucosylserine" EXACT RESID-alternate []
synonym	"OGlcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 9 H 15 N 1 O 7"
xref	MassAvg: "249.22"
xref	MassMono: "249.084852"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine
is_a	MOD:00433 glucosylated residue ! glucosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)

2.805. MOD:00805 O-(N-acetylamino)glucosyl-L-serine

Table 807. Term [MOD:00805]
id	MOD:00805
name	O-(N-acetylamino)glucosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-(N-acetylaminoglucosyl)-L-serine." [PubMed:3086323, PubMed:8404891, RESID:AA0398]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(2-acetamido-2-deoxy-beta-D-glucopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GlcNAc)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (HexNAc)" EXACT UniProt-feature []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"O-(2-acetylamino-2-deoxy-beta-D-glucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O-(N-acetylamino)glucosyl-L-serine" EXACT RESID-name []
synonym	"O-(N-acetylglucosaminyl)serine" EXACT RESID-alternate []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O-seryl-beta-N-acetylglucosaminide" EXACT RESID-alternate []
synonym	"O3-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O3-(N-acetylglucosaminyl)serine" EXACT RESID-alternate []
synonym	"OGlcNAcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 11 H 18 N 2 O 7"
xref	MassAvg: "290.27"
xref	MassMono: "290.111401"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:01675 O-(N-acetylamino)hexosyl-L-serine ! O-(N-acetylamino)hexosyl-L-serine

2.806. MOD:00806 O-(N-acetylamino)glucosyl-L-threonine

Table 808. Term [MOD:00806]
id	MOD:00806
name	O-(N-acetylamino)glucosyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O3-(N-acetylaminoglucosyl)-L-threonine." [PubMed:3086323, PubMed:8404891, RESID:AA0399]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(2-acetamido-2-deoxy-beta-D-glucopyranosyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GlcNAc)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (HexNAc)" EXACT UniProt-feature []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"O-(2-acetylamino-2-deoxy-beta-D-glucopyranosyl)-L-threonine" EXACT RESID-alternate []
synonym	"O-(N-acetylamino)glucosyl-L-threonine" EXACT RESID-name []
synonym	"O-(N-acetylglucosaminyl)-L-threonine" EXACT RESID-alternate []
synonym	"O-glycosylthreonine" EXACT RESID-alternate []
synonym	"O-threonyl-beta-N-acetylglucosaminide" EXACT RESID-alternate []
synonym	"O3-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-threonine" EXACT RESID-alternate []
synonym	"O3-(N-acetylglucosaminyl)threonine" EXACT RESID-alternate []
synonym	"OGlcNAcThr" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 20 N 2 O 7"
xref	MassAvg: "304.30"
xref	MassMono: "304.127051"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:01676 O-(N-acetylamino)hexosyl-L-threonine ! O-(N-acetylamino)hexosyl-L-threonine

2.807. MOD:00807 pyruvic acid (Ser)

Table 809. Term [MOD:00807]
id	MOD:00807
name	pyruvic acid (Ser)
def	"A protein modification that effectively converts an L-serine residue to pyruvic acid." [DeltaMass:23, PubMed:10085076, PubMed:3042771, PubMed:8464063, RESID:AA0127#SER, UniMod:385#S]
comment	DeltaMass gives mass 70 and difference mass -16 with no formula
subset	PSI-MOD-slim
synonym	"2-oxopropanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES Pyruvic acid (Ser)" EXACT UniProt-feature []
synonym	"Pyruvate" EXACT DeltaMass-label []
synonym	"pyruvic acid" EXACT RESID-name []
synonym	"Pyruvoyl- (Serine)" EXACT DeltaMass-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 3 H 3 O 2"
xref	MassAvg: "71.06"
xref	MassMono: "71.013304"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01154 pyruvic acid ! pyruvic acid
is_a	MOD:01160 deaminated residue ! deaminated residue

2.808. MOD:00808 O-galactosyl-L-serine

Table 810. Term [MOD:00808]
id	MOD:00808
name	O-galactosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-galactosylserine." [PubMed:666730, RESID:AA0400]
synonym	"(2S)-2-amino-3-(alpha-D-galactopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (Gal)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Hex)" EXACT UniProt-feature []
synonym	"O-galactosyl-L-serine" EXACT RESID-name []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O3-galactosylserine" EXACT RESID-alternate []
synonym	"OGalSer" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 9 H 15 N 1 O 7"
xref	MassAvg: "249.22"
xref	MassMono: "249.084852"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine
is_a	MOD:00476 galactosylated residue ! galactosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)

2.809. MOD:00809 O-galactosyl-L-threonine

Table 811. Term [MOD:00809]
id	MOD:00809
name	O-galactosyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O3-galactosylthreonine." [PubMed:2673008, RESID:AA0401]
synonym	"(2S,3R)-2-amino-3-(alpha-D-galactopyranosyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (Gal)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Hex)" EXACT UniProt-feature []
synonym	"O-galactosyl-L-threonine" EXACT RESID-name []
synonym	"O-glycosylthreonine" EXACT RESID-alternate []
synonym	"O3-galactosylthreonine" EXACT RESID-alternate []
synonym	"OGalThr" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 10 H 17 N 1 O 7"
xref	MassAvg: "263.25"
xref	MassMono: "263.100502"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00476 galactosylated residue ! galactosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:01348 O-hexosylated threonine ! O-hexosylated threonine

2.810. MOD:00810 O-mannosyl-L-serine

Table 812. Term [MOD:00810]
id	MOD:00810
name	O-mannosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-mannosylserine." [PubMed:391559, RESID:AA0402]
synonym	"(2S)-2-amino-3-(alpha-D-mannopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (Hex)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Man)" EXACT UniProt-feature []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O-mannopyranosylserine" EXACT RESID-alternate []
synonym	"O-mannosyl-L-serine" EXACT RESID-name []
synonym	"O3-mannosylserine" EXACT RESID-alternate []
synonym	"OManSer" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 9 H 15 N 1 O 7"
xref	MassAvg: "249.22"
xref	MassMono: "249.084852"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine
is_a	MOD:00595 mannosylated residue ! mannosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)

2.811. MOD:00811 O-mannosyl-L-threonine

Table 813. Term [MOD:00811]
id	MOD:00811
name	O-mannosyl-L-threonine
def	"a protein modification that effectively forms a O3-mannosylthreonine" [PubMed:391559, RESID:AA0403]
synonym	"(2S,3R)-2-amino-3-(alpha-D-mannopyranosyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (Hex)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Man)" EXACT UniProt-feature []
synonym	"O-glycosylthreonine" EXACT RESID-alternate []
synonym	"O-mannosyl-L-threonine" EXACT RESID-name []
synonym	"O3-mannosylthreonine" EXACT RESID-alternate []
synonym	"OManThr" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 10 H 17 N 1 O 7"
xref	MassAvg: "263.25"
xref	MassMono: "263.100502"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00595 mannosylated residue ! mannosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:01348 O-hexosylated threonine ! O-hexosylated threonine

2.812. MOD:00812 O-fucosyl-L-serine

Table 814. Term [MOD:00812]
id	MOD:00812
name	O-fucosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to an O-fucosylserine." [PubMed:10734111, PubMed:11067851, PubMed:11344537, PubMed:12096136, PubMed:1517205, PubMed:15189151, PubMed:1904059, PubMed:3311742, PubMed:3578767, RESID:AA0404, UniMod:295#S]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(6-deoxy-alpha-D-galactopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (dHex)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Fuc)" EXACT UniProt-feature []
synonym	"dHex" RELATED PSI-MS-label []
synonym	"Fucose" RELATED UniMod-description []
synonym	"O-fucosyl-L-serine" EXACT RESID-name []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O3-fucosylserine" EXACT RESID-alternate []
synonym	"OFucSer" EXACT PSI-MOD-label []
xref	DiffAvg: "146.14"
xref	DiffFormula: "C 6 H 10 N 0 O 4"
xref	DiffMono: "146.057909"
xref	Formula: "C 9 H 15 N 1 O 6"
xref	MassAvg: "233.22"
xref	MassMono: "233.089937"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine
is_a	MOD:00614 fucosylated ! fucosylated

2.813. MOD:00813 O-fucosyl-L-threonine

Table 815. Term [MOD:00813]
id	MOD:00813
name	O-fucosyl-L-threonine
def	"A protein modification that effectively converts an threonine residue to an O-fucosylthreonine." [PubMed:11344537, PubMed:11857757, PubMed:15189151, PubMed:1740125, PubMed:1900431, RESID:AA0405, UniMod:295#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(6-deoxy-alpha-D-galactopyranosyloxy)butanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (dHex)" EXACT UniProt-feature []
synonym	"CARBOHYD O-linked (Fuc)" EXACT UniProt-feature []
synonym	"dHex" RELATED PSI-MS-label []
synonym	"Fucose" RELATED UniMod-description []
synonym	"O-fucosyl-L-threonine" EXACT RESID-name []
synonym	"O-glycosylthreonine" EXACT RESID-alternate []
synonym	"O3-fucosylthreonine" EXACT RESID-alternate []
synonym	"OFucThr" EXACT PSI-MOD-label []
xref	DiffAvg: "146.14"
xref	DiffFormula: "C 6 H 10 N 0 O 4"
xref	DiffMono: "146.057909"
xref	Formula: "C 10 H 17 N 1 O 6"
xref	MassAvg: "247.25"
xref	MassMono: "247.105587"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine
is_a	MOD:00614 fucosylated ! fucosylated

2.814. MOD:00814 O-xylosyl-L-serine

Table 816. Term [MOD:00814]
id	MOD:00814
name	O-xylosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-xylosylserine." [PubMed:8747463, RESID:AA0406]
comment	One glycosylated serine with weak electron density was modeled as O3-alpha-xylosylserine, while O3-alpha-mannosyl serine and threonine were modeled at ten other positions. The authors do not discuss this exception or provide chemical evidence for it. Since an O3-xylosyl serine modification has not been reported in any other fungal proteins, the modification is probably also an O3-alpha-mannosyl serine, see MOD:00810 [JSG].
synonym	"(2S)-2-amino-3-(alpha-D-xylopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"O-(beta-D-xylopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O-glycosylserine" EXACT RESID-alternate []
synonym	"O-xylosyl-L-serine" EXACT RESID-name []
synonym	"O3-xylosylserine" EXACT RESID-alternate []
synonym	"OXylSer" EXACT PSI-MOD-label []
xref	DiffAvg: "132.12"
xref	DiffFormula: "C 5 H 8 N 0 O 4"
xref	DiffMono: "132.042259"
xref	Formula: "C 8 H 13 N 1 O 6"
xref	MassAvg: "219.19"
xref	MassMono: "219.074287"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.815. MOD:00815 molybdopterin

Table 817. Term [MOD:00815]
id	MOD:00815
name	molybdopterin
def	"OBSOLETE because redundant with MOD:00151. Remap to MOD:00151." [PubMed:14527393, PubMed:7878465, PubMed:9428520]
xref	DiffAvg: "520.27"
xref	DiffFormula: "C 10 H 11 Mo 1 N 5 O 8 P 1 S 2"
xref	DiffMono: "521.884074"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.816. MOD:00816 S-stearoyl-L-cysteine

Table 818. Term [MOD:00816]
id	MOD:00816
name	S-stearoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-stearoyl-L-cysteine." [DeltaMass:0, PubMed:2371783, PubMed:3143715, PubMed:8761467, RESID:AA0407]
comment	From DeltaMass: Average Mass: 266
subset	PSI-MOD-slim
synonym	"®-2-amino-3-(octadecanoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(octadecanoylthio)propanoic acid" EXACT RESID-alternate []
synonym	"cysteine octadecanoate thioester" EXACT RESID-alternate []
synonym	"cysteine stearate thioester" EXACT RESID-alternate []
synonym	"LIPID S-stearoyl cysteine" EXACT UniProt-feature []
synonym	"S-stearoyl-L-cysteine" EXACT RESID-name []
synonym	"SSteCys" EXACT PSI-MOD-label []
synonym	"Stearoylation" EXACT DeltaMass-label []
xref	DiffAvg: "266.47"
xref	DiffFormula: "C 18 H 34 N 0 O 1 S 0"
xref	DiffMono: "266.260966"
xref	Formula: "C 21 H 39 N 1 O 2 S 1"
xref	MassAvg: "369.61"
xref	MassMono: "369.270150"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00672 S-acylated residue ! S-acylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.817. MOD:00817 3'-geranyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan

Table 819. Term [MOD:00817]
id	MOD:00817
name	3'-geranyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 3'-geranyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan." [ChEBI:35304, PubMed:16407988, PubMed:8168130, RESID:AA0408]
synonym	"(2S,3aR,8aS)-3a-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-3-geranyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophan" EXACT RESID-alternate []
synonym	"3'-geranyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan" EXACT RESID-name []
synonym	"3’Ger2’N2cycTrp" EXACT PSI-MOD-label []
synonym	"LIPID 3'-geranyl-2',N2-cyclotryptophan" EXACT UniProt-feature []
xref	DiffAvg: "136.24"
xref	DiffFormula: "C 10 H 16 N 0 O 0"
xref	DiffMono: "136.125201"
xref	Formula: "C 21 H 26 N 2 O 1"
xref	MassAvg: "322.45"
xref	MassMono: "322.204513"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:01115 isoprenylated tryptophan ! isoprenylated tryptophan

2.818. MOD:00818 glycosylphosphatidylinositolated residue

Table 820. Term [MOD:00818]
id	MOD:00818
name	glycosylphosphatidylinositolated residue
def	"A protein modification that effectively converts a residue to a glycosylphosphatidylinositolethanolamidated." [PubMed:12643538, UniMod:394#C-term]
synonym	"glycosylphosphatidylinositol" RELATED UniMod-description []
synonym	"GPIanchor" RELATED UniMod-interim []
synonym	"GPIRes" EXACT PSI-MOD-label []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.819. MOD:00819 L-2-aminobutanoic acid (Glu)

Table 821. Term [MOD:00819]
id	MOD:00819
name	L-2-aminobutanoic acid (Glu)
def	"A protein modification that effectively converts an L-glutamic acid residue to L-2-aminobutanoic acid." [ChEBI:35619, DeltaMass:0, PubMed:11740505, RESID:AA0409]
synonym	"(S)-2-aminobutanoic acid" EXACT RESID-systematic []
synonym	"Abu" EXACT DeltaMass-label []
synonym	"Abu" EXACT PSI-MOD-label []
synonym	"alpha-amino-n-butyric acid" EXACT PSI-MOD-alternate []
synonym	"alpha-aminobutyric acid" EXACT PSI-MOD-alternate []
synonym	"butyrine" EXACT PSI-MOD-alternate []
synonym	"dCbxGlu" EXACT PSI-MOD-alternate []
synonym	"L-2-amino-n-butyric acid" EXACT RESID-alternate []
synonym	"L-2-aminobutanoic acid" EXACT RESID-name []
synonym	"L-2-aminobutyric acid" EXACT RESID-alternate []
synonym	"L-alpha-amino-n-butyric acid" EXACT RESID-alternate []
synonym	"L-alpha-aminobutyric acid" EXACT RESID-alternate []
synonym	"L-butyrine" EXACT RESID-alternate []
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "C 4 H 7 N 1 O 1"
xref	MassAvg: "85.11"
xref	MassMono: "85.052764"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.820. MOD:00820 2-imino-alanine 5-imidazolinone glycine

Table 822. Term [MOD:00820]
id	MOD:00820
name	2-imino-alanine 5-imidazolinone glycine
def	"A protein modification that effectively crosslinks an L-aspartic acid residue and a glycine residue to form 2-imino-alanine 5-imidazolinone glycine." [PubMed:16627946, RESID:AA0410]
comment	Cross-link 2; carboxamidine.
synonym	"(2-ethanimidoyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acid" EXACT RESID-systematic []
synonym	"2,N-didehydroalanyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"2-(1-iminoethyl)-1-carboxymethyl-1-imidazolin-5-one" EXACT RESID-alternate []
synonym	"2-imino-alanine 5-imidazolinone glycine" EXACT RESID-name []
synonym	"2-imino-alanyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"[2-(1-iminoethyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid" EXACT RESID-alternate []
synonym	"alanyl-5-imidazolinone glycine" EXACT RESID-alternate []
synonym	"para-hydroxybenzylidene-imidazolidinone chromophore" EXACT RESID-alternate []
synonym	"red fluorescent protein zRFP574 chromophore" EXACT RESID-alternate []
xref	DiffAvg: "-64.04"
xref	DiffFormula: "C -1 H -4 N 0 O -3"
xref	DiffMono: "-64.016044"
xref	Formula: "C 5 H 4 N 2 O 1"
xref	MassAvg: "108.10"
xref	MassMono: "108.032363"
xref	Origin: "D, G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01882 5-imidazolinone ring crosslinked residues (Gly) ! 5-imidazolinone ring crosslinked residues (Gly)

2.821. MOD:00821 S-(L-alanyl)-L-cysteine

Table 823. Term [MOD:00821]
id	MOD:00821
name	S-(L-alanyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-alanine residue and an L-cysteine residue by a thioester bond to form S-(L-alanyl)-L-cysteine." [PubMed:11807079, RESID:AA0411]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-aminopropanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"alanine cysteine thioester" EXACT RESID-alternate []
synonym	"CROSSLNK Alanyl cysteine thioester (Cys-Ala)" EXACT UniProt-feature []
synonym	"S-(2-aminopropanoyl)cysteine" EXACT RESID-alternate []
synonym	"S-(L-alanyl)-L-cysteine" EXACT RESID-name []
synonym	"XLNK1AlaSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 9 N 2 O 2 S 1"
xref	MassAvg: "173.21"
xref	MassMono: "173.038474"
xref	Origin: "A, C"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.822. MOD:00822 S-(L-leucyl)-L-cysteine

Table 824. Term [MOD:00822]
id	MOD:00822
name	S-(L-leucyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-leucine residue and an L-cysteine residue by a thioester bond to form S-(L-leucyl)-L-cysteine." [PubMed:12591958, RESID:AA0412]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-amino-4-methylpentanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Leucyl cysteine thioester (Cys-Leu)" EXACT UniProt-feature []
synonym	"leucine cysteine thioester" EXACT RESID-alternate []
synonym	"S-(2-amino-4-methylpentanoyl)cysteine" EXACT RESID-alternate []
synonym	"S-(L-leucyl)-L-cysteine" EXACT RESID-name []
synonym	"XLNK1LeuSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 9 H 15 N 2 O 2 S 1"
xref	MassAvg: "215.29"
xref	MassMono: "215.085424"
xref	Origin: "C, L"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.823. MOD:00823 S-(L-methionyl)-L-cysteine

Table 825. Term [MOD:00823]
id	MOD:00823
name	S-(L-methionyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-methionine residue and an L-cysteine residue by a thioester bond to form S-(L-methionyl)-L-cysteine." [PubMed:12146974, RESID:AA0413]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-amino-4-(methylsulfanyl)butanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Methionyl cysteine thioester (Cys-Met)" EXACT UniProt-feature []
synonym	"methionine cysteine thioester" EXACT RESID-alternate []
synonym	"S-(2-amino-4-methylthiobutanoyl)cysteine" EXACT RESID-alternate []
synonym	"S-(L-methionyl)-L-cysteine" EXACT RESID-name []
synonym	"XLNK1MetSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 8 H 13 N 2 O 2 S 2"
xref	MassAvg: "233.32"
xref	MassMono: "233.041845"
xref	Origin: "C, M"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.824. MOD:00824 dehydroalanine (Tyr)

Table 826. Term [MOD:00824]
id	MOD:00824
name	dehydroalanine (Tyr)
def	"A protein modification that effectively converts an L-tyrosine residue to dehydroalanine." [PubMed:10220322, PubMed:1547888, PubMed:1815586, PubMed:2914619, PubMed:6838602, PubMed:7947813, PubMed:8239649, RESID:AA0181#TYR, UniMod:400]
comment	incidental to RESID:AA0178
synonym	"2,3-didehydroalanine" EXACT RESID-alternate []
synonym	"2-aminoacrylic acid" EXACT RESID-alternate []
synonym	"2-aminopropenoic acid" EXACT RESID-systematic []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"anhydroserine" EXACT RESID-alternate []
synonym	"dehydroalanine" EXACT RESID-name []
synonym	"Dha" EXACT RESID-alternate []
synonym	"dHAla(Tyr)" EXACT PSI-MOD-label []
xref	DiffAvg: "-94.11"
xref	DiffFormula: "C -6 H -6 N 0 O -1"
xref	DiffMono: "-94.041865"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01168 dehydroalanine ! dehydroalanine

2.825. MOD:00825 S-(L-phenylalanyl)-L-cysteine

Table 827. Term [MOD:00825]
id	MOD:00825
name	S-(L-phenylalanyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-phenylalanine residue and an L-cysteine residue by a thioester bond to form S-(L-phenylalaninyl)-L-cysteine." [PubMed:12591958, RESID:AA0414]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-amino-3-phenylpropanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Phenylalanyl cysteine thioester (Cys-Phe)" EXACT UniProt-feature []
synonym	"phenylalanine cysteine thioester" EXACT RESID-alternate []
synonym	"S-(2-amino-3-phenylpropanoyl)cysteine" EXACT RESID-alternate []
synonym	"S-(L-phenylalanyl)-L-cysteine" EXACT RESID-name []
synonym	"XLNK1PheSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 12 H 13 N 2 O 2 S 1"
xref	MassAvg: "249.31"
xref	MassMono: "249.069774"
xref	Origin: "C, F"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.826. MOD:00826 S-(L-threonyl)-L-cysteine

Table 828. Term [MOD:00826]
id	MOD:00826
name	S-(L-threonyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-threonine residue and an L-cysteine residue by a thioester bond to form S-(L-threonyl)-L-cysteine." [PubMed:15268951, RESID:AA0415]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S,3R)-2-amino-3-hydroxybutanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Threonyl cysteine thioester (Cys-Thr)" EXACT UniProt-feature []
synonym	"S-(2-amino-3-hydroxybutanoyl)cysteine" EXACT RESID-alternate []
synonym	"S-(L-threonyl)-L-cysteine" EXACT RESID-name []
synonym	"threonine cysteine thioester" EXACT RESID-alternate []
synonym	"XLNK1ThrSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 11 N 2 O 3 S 1"
xref	MassAvg: "203.24"
xref	MassMono: "203.049038"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.827. MOD:00827 S-(L-tyrosyl)-L-cysteine

Table 829. Term [MOD:00827]
id	MOD:00827
name	S-(L-tyrosyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-tyrosine residue and an L-cysteine residue by a thioester bond to form S-(L-tyrosyl)-L-cysteine." [PubMed:11807079, RESID:AA0416]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Tyrosyl cysteine thioester (Cys-Tyr)" EXACT UniProt-feature []
synonym	"S-(L-tyrosyl)-L-cysteine" EXACT RESID-name []
synonym	"S-[2-amino-3-(4-hydoxyphenyl)propanoyl]cysteine" EXACT RESID-alternate []
synonym	"tyrosine cysteine thioester" EXACT RESID-alternate []
synonym	"XLNK1TyrSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 12 H 13 N 2 O 3 S 1"
xref	MassAvg: "265.31"
xref	MassMono: "265.064688"
xref	Origin: "C, Y"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.828. MOD:00828 S-(L-tryptophanyl)-L-cysteine

Table 830. Term [MOD:00828]
id	MOD:00828
name	S-(L-tryptophanyl)-L-cysteine
def	"A protein modification that effectively crosslinks an L-tryptophan residue and an L-cysteine residue by a thioester bond to form S-(L-tryptophanyl)-L-cysteine." [PubMed:16030216, RESID:AA0417]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Tryptophanyl cysteine thioester (Cys-Trp)" EXACT UniProt-feature []
synonym	"S-(L-tryptophanyl)-L-cysteine" EXACT RESID-name []
synonym	"S-[2-amino-3-(1H-indol-3-yl)propanoyl]cysteine" EXACT RESID-alternate []
synonym	"tryptophan cysteine thioester" EXACT RESID-alternate []
synonym	"XLNK1TrpSCys" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 14 H 14 N 3 O 2 S 1"
xref	MassAvg: "288.35"
xref	MassMono: "288.080673"
xref	Origin: "C, W"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.829. MOD:00829 O-(L-phenylalanyl)-L-serine

Table 831. Term [MOD:00829]
id	MOD:00829
name	O-(L-phenylalanyl)-L-serine
def	"A protein modification that effectively crosslinks an L-phenylalanine residue and an L-serine residue by an ester bond to form S-(L-phenylalaninyl)-L-serine." [PubMed:12591958, RESID:AA0418]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-([(2S)-2-amino-3-phenylpropanoyl]oxy)propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Phenylalanyl serine ester (Ser-Phe)" EXACT UniProt-feature []
synonym	"O-(2-amino-3-phenylpropanoyl)serine" EXACT RESID-alternate []
synonym	"O-(L-phenylalanyl)-L-serine" EXACT RESID-name []
synonym	"phenylalanine serine ester" EXACT RESID-alternate []
synonym	"XLNK1PheOSer" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 12 H 13 N 2 O 3"
xref	MassAvg: "233.25"
xref	MassMono: "233.092617"
xref	Origin: "F, S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.830. MOD:00830 N-methyl-L-proline

Table 832. Term [MOD:00830]
id	MOD:00830
name	N-methyl-L-proline
def	"A protein modification that effectively converts an L-proline residue to an N-methyl-L-proline." [PubMed:3127388, RESID:AA0419]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
subset	PSI-MOD-slim
synonym	"(S)-1-methylpyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"1-methylpyrrolidine-2-carboxylic acid" EXACT RESID-alternate []
synonym	"hygric acid" EXACT RESID-alternate []
synonym	"MOD_RES N-methylproline" EXACT UniProt-feature []
synonym	"N-methyl-L-proline" EXACT RESID-name []
synonym	"N-methylated L-proline" EXACT PSI-MOD-alternate []
synonym	"NMePro" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 10 N 1 O 1"
xref	MassAvg: "112.15"
xref	MassMono: "112.076239"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01417 monomethylated proline ! monomethylated proline
is_a	MOD:01462 N-methylated proline ! N-methylated proline
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue

2.831. MOD:00831 N4-(N-acetylamino)glucosyl-L-asparagine

Table 833. Term [MOD:00831]
id	MOD:00831
name	N4-(N-acetylamino)glucosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine." [PubMed:111247, PubMed:1694179, PubMed:5490222, RESID:AA0151#var]
subset	PSI-MOD-slim
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"N4GlcNAcAsn" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 19 N 3 O 7"
xref	MassAvg: "317.30"
xref	MassMono: "317.122300"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:01674 N4-(N-acetylamino)hexosyl-L-asparagine ! N4-(N-acetylamino)hexosyl-L-asparagine

2.832. MOD:00832 N4-(N-acetylamino)galactosyl-L-asparagine

Table 834. Term [MOD:00832]
id	MOD:00832
name	N4-(N-acetylamino)galactosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-(N-acetaminogalactosyl)-L-asparagine." [PubMed:8262914, RESID:AA0420]
synonym	"(2S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"N4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-L-asparagine" EXACT RESID-alternate []
synonym	"N4-(2-acetylamino-2-deoxy-beta-D-galactopyranosyl)-L-asparagine" EXACT RESID-alternate []
synonym	"N4-(N-acetylamino)galactosyl-L-asparagine" EXACT RESID-name []
synonym	"N4-(N-acetylgalactosaminyl)asparagine" EXACT RESID-alternate []
synonym	"N4-asparagine-beta-N-acetylgalactosaminide" EXACT RESID-alternate []
synonym	"N4-glycosyl-L-asparagine" EXACT RESID-alternate []
synonym	"N4-glycosylasparagine" EXACT RESID-alternate []
synonym	"N4GalNAcAsn" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 19 N 3 O 7"
xref	MassAvg: "317.30"
xref	MassMono: "317.122300"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00563 N-acetylaminogalactosylated residue ! N-acetylaminogalactosylated residue
is_a	MOD:01674 N4-(N-acetylamino)hexosyl-L-asparagine ! N4-(N-acetylamino)hexosyl-L-asparagine

2.833. MOD:00833 N4-glucosyl-L-asparagine

Table 835. Term [MOD:00833]
id	MOD:00833
name	N4-glucosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-glucosyl-asparagine." [PubMed:1569073, PubMed:3410849, RESID:AA0421]
synonym	"(2S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD N-linked (Glc)" EXACT UniProt-feature []
synonym	"N4-(D-glucopyranosyl)-L-asparagine" EXACT RESID-alternate []
synonym	"N4-asparagine-glucoside" EXACT RESID-alternate []
synonym	"N4-glucosyl-L-asparagine" EXACT RESID-name []
synonym	"N4-glucosylasparagine" EXACT RESID-alternate []
synonym	"N4-glycosyl-L-asparagine" EXACT RESID-alternate []
synonym	"N4-glycosylasparagine" EXACT RESID-alternate []
synonym	"N4GlcAsn" EXACT PSI-MOD-label []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 10 H 16 N 2 O 7"
xref	MassAvg: "276.25"
xref	MassMono: "276.095751"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00433 glucosylated residue ! glucosylated residue
is_a	MOD:00761 monohexosylated (Hex1) ! monohexosylated (Hex1)
is_a	MOD:01346 N4-hexosylated asparagine ! N4-hexosylated asparagine

2.834. MOD:00834 O-(N-acetylamino)fucosyl-L-serine

Table 836. Term [MOD:00834]
id	MOD:00834
name	O-(N-acetylamino)fucosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-(N-acetamino)fucosylserine." [PubMed:11342554, PubMed:12010970, RESID:AA0422]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(2-acetamido-2-deoxy-beta-D-fucopyranosyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"O-(2-acetylamino-2-deoxy-beta-D-fucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O-(N-acetylamino)fucosyl-L-serine" EXACT RESID-name []
synonym	"O-(N-acetylfucosaminyl)serine" EXACT RESID-alternate []
synonym	"O-seryl-beta-N-acetylfucosaminide" EXACT RESID-alternate []
synonym	"O3-(2-acetamido-2-deoxy-beta-D-fucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O3-(N-acetylfucosaminyl)serine" EXACT RESID-alternate []
synonym	"OFucNAcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "187.19"
xref	DiffFormula: "C 8 H 13 N 1 O 4"
xref	DiffMono: "187.084458"
xref	Formula: "C 11 H 18 N 2 O 6"
xref	MassAvg: "274.27"
xref	MassMono: "274.116486"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.835. MOD:00835 L-3-oxoalanine (Ser)

Table 837. Term [MOD:00835]
id	MOD:00835
name	L-3-oxoalanine (Ser)
def	"A protein modification that effectively converts an L-serine residue to L-oxoalanine." [DeltaMass:349, PubMed:14563551, PubMed:7628016, PubMed:8681943, PubMed:9276974, PubMed:9478923, RESID:AA0185#SER, UniMod:401#S]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-oxopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-oxopropionic acid" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine" RELATED RESID-misnomer []
synonym	"dehydrogenated serine residue" RELATED UniMod-description []
synonym	"Didehydro" RELATED PSI-MS-label []
synonym	"formylglycine" RELATED UniMod-alternate []
synonym	"formylglycine (from serine)" EXACT DeltaMass-label []
synonym	"L-3-oxoalanine" EXACT RESID-name []
synonym	"L-amino-malonic acid semialdehyde" EXACT RESID-alternate []
synonym	"L-aminomalonaldehydic acid" EXACT RESID-alternate []
synonym	"L-serinesemialdehyde" RELATED RESID-misnomer []
synonym	"MOD_RES 3-oxoalanine (Ser)" EXACT UniProt-feature []
synonym	"oxoalanine" RELATED UniMod-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 3 H 3 N 1 O 2"
xref	MassAvg: "85.06"
xref	MassMono: "85.016378"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01169 L-3-oxoalanine ! L-3-oxoalanine
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.836. MOD:00836 deuterium disubstituted residue

Table 838. Term [MOD:00836]
id	MOD:00836
name	deuterium disubstituted residue
def	"A protein modification that effectively substitutes two (2)H deuterium atoms for two (1)H protium atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"D(H)2Res" EXACT PSI-MOD-label []
is_a	MOD:00786 deuterium substituted residue ! deuterium substituted residue

2.837. MOD:00837 deuterium tetrasubstituted residue

Table 839. Term [MOD:00837]
id	MOD:00837
name	deuterium tetrasubstituted residue
def	"A protein modification that effectively substitutes four (2)H deuterium atoms for four (1)H protium atoms." [PubMed:18688235]
synonym	"D(H)4Res" EXACT PSI-MOD-label []
is_a	MOD:00786 deuterium substituted residue ! deuterium substituted residue

2.838. MOD:00838 3x(2)H labeled L-leucine

Table 840. Term [MOD:00838]
id	MOD:00838
name	3x(2)H labeled L-leucine
def	"A protein modification that effectively substitutes three (1)H protium atoms with three (2)H deuterium atoms to produce 3x(2)H labeled L-leucine." [UniMod:262#L]
synonym	"D(H)3Leu" EXACT PSI-MOD-label []
synonym	"Label:2H(3)" RELATED PSI-MS-label []
synonym	"Trideuteration" RELATED UniMod-description []
xref	DiffAvg: "3.02"
xref	DiffFormula: "(1)H -3 (2)H 3"
xref	DiffMono: "3.018830"
xref	Formula: "C 6 (1)H 8 (2)H 3 N 1 O 1"
xref	MassAvg: "116.10"
xref	MassMono: "116.102894"
xref	Origin: "L"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00585 deuterium trisubstituted residue ! deuterium trisubstituted residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.839. MOD:00839 (2)H deuterium labeled residue

Table 841. Term [MOD:00839]
id	MOD:00839
name	(2)H deuterium labeled residue
def	"A protein modification that effectively substitutes atoms of particular common isotopes with atoms of or groups containing deuteriumm, (2)H." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00702 isotope labeled residue ! isotope labeled residue

2.840. MOD:00840 isocyanate reagent derivatized residue

Table 842. Term [MOD:00840]
id	MOD:00840
name	isocyanate reagent derivatized residue
def	"A protein modification produced by formation of an adduct with an isocyanate compound." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.841. MOD:00841 isothiocyanate reagent derivatized residue

Table 843. Term [MOD:00841]
id	MOD:00841
name	isothiocyanate reagent derivatized residue
def	"A protein modification produced by formation of an adduct with an isothiocyanate compound." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.842. MOD:00842 (13)C labeled residue

Table 844. Term [MOD:00842]
id	MOD:00842
name	(13)C labeled residue
def	"A protein modification that effectively substitutes atoms of particular common isotopes with atoms of or groups containing (13)C." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00702 isotope labeled residue ! isotope labeled residue

2.843. MOD:00843 (15)N labeled residue

Table 845. Term [MOD:00843]
id	MOD:00843
name	(15)N labeled residue
def	"A protein modification that effectively substitutes atoms of particular common isotopes with atoms of or groups containing (15)N." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00702 isotope labeled residue ! isotope labeled residue

2.844. MOD:00844 (18)O labeled residue

Table 846. Term [MOD:00844]
id	MOD:00844
name	(18)O labeled residue
def	"A protein modification that effectively substitutes atoms of particular common isotopes with atoms of or groups containing (18)O." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00702 isotope labeled residue ! isotope labeled residue

2.845. MOD:00845 (18)O substituted residue

Table 847. Term [MOD:00845]
id	MOD:00845
name	(18)O substituted residue
def	"A protein modification that effectively substitutes one or more (18)O atoms for (16)O atoms." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00844 (18)O labeled residue ! (18)O labeled residue

2.846. MOD:00846 levuglandinyl (prostaglandin H2) adduct

Table 848. Term [MOD:00846]
id	MOD:00846
name	levuglandinyl (prostaglandin H2) adduct
def	"stub" [PubMed:18688235]
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.847. MOD:00847 (18)O disubstituted residue

Table 849. Term [MOD:00847]
id	MOD:00847
name	(18)O disubstituted residue
def	"A protein modification that effectively substitutes two (18)O atom for two (16)O atoms." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00845 (18)O substituted residue ! (18)O substituted residue

2.848. MOD:00848 reagent derivatized residue

Table 850. Term [MOD:00848]
id	MOD:00848
name	reagent derivatized residue
def	"A protein modification that is produced by formation of an adduct with a particular compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.849. MOD:00849 potassium containing modified residue

Table 851. Term [MOD:00849]
id	MOD:00849
name	potassium containing modified residue
def	"A protein modification that effectively substitutes a potassium atom for a hydrogen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"KRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.850. MOD:00850 unnatural residue

Table 852. Term [MOD:00850]
id	MOD:00850
name	unnatural residue
def	"A protein modification that inserts or replaces a residue with an unnatural residue that is not considered to be derived from a natural residue by some chemical process." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.851. MOD:00851 (18)O labeled deamidated residue

Table 853. Term [MOD:00851]
id	MOD:00851
name	(18)O labeled deamidated residue
def	"A protein modification that effectively replaces a carboxamido group with a carboxyl group labeled with (18)O." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00400 deamidated residue ! deamidated residue
is_a	MOD:00844 (18)O labeled residue ! (18)O labeled residue

2.852. MOD:00852 1x(18)O labeled deamidated residue

Table 854. Term [MOD:00852]
id	MOD:00852
name	1x(18)O labeled deamidated residue
def	"A protein modification that effectively replaces a carboxamido group with a carboxyl group labeled with one (18)O." [PubMed:8382902, UniMod:366]
subset	PSI-MOD-slim
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00851 (18)O labeled deamidated residue ! (18)O labeled deamidated residue

2.853. MOD:00853 2x(18)O labeled deamidated residue

Table 855. Term [MOD:00853]
id	MOD:00853
name	2x(18)O labeled deamidated residue
def	"A protein modification that effectively replaces a carboxamido group with a carboxyl group labeled with two (18)O." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "4.99"
xref	DiffFormula: "H -1 N -1 (16)O -1 (18)O 2"
xref	DiffMono: "4.992508"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00851 (18)O labeled deamidated residue ! (18)O labeled deamidated residue

2.854. MOD:00854 protonated L-lysine (L-lysinium) residue

Table 856. Term [MOD:00854]
id	MOD:00854
name	protonated L-lysine (L-lysinium) residue
def	"A protein modification that effectively converts an L-lysine to L-lysinium (protonated L-lysine)." [PubMed:18688235]
comment	Some sources compute the difference formula for charged, quatenary modified lysine based on protonated lysine rather than neutral lysine residue. In such cases, a comparable difference formula can be calculated based on this derivative.
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 13 N 2 O 1"
xref	MassAvg: "129.18"
xref	MassMono: "129.102239"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01699 protonated residue ! protonated residue

2.855. MOD:00855 N6,N6,N6-trimethyl-L-lysine (from L-lysinium residue)

Table 857. Term [MOD:00855]
id	MOD:00855
name	N6,N6,N6-trimethyl-L-lysine (from L-lysinium residue)
def	"A protein modification that effectively converts an L-lysinium (N6-protonated L-lysine) residue to an N6,N6,N6-trimethyl-L-lysine." [DeltaMass:0, OMSSA:15, PubMed:12590383, PubMed:3145979, PubMed:4304194, PubMed:6778808, PubMed:7093227, PubMed:8453381, UniMod:37#K]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N6Me3+Lys process (MOD:00083) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N6Me3Lys" EXACT PSI-MOD-label []
synonym	"trimethylk" EXACT OMSSA-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "C 9 H 19 N 2 O 1"
xref	MassAvg: "171.26"
xref	MassMono: "171.149190"
xref	Origin: "MOD:00854"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00430 trimethylated residue ! trimethylated residue
relationship	derives_from MOD:00854 protonated L-lysine (L-lysinium) residue ! protonated L-lysine (L-lysinium) residue

2.856. MOD:00856 protonated L-alanine (L-alaninium) residue

Table 858. Term [MOD:00856]
id	MOD:00856
name	protonated L-alanine (L-alaninium) residue
def	"A protein modification that effectively converts an L-alanine residue to an L-alaninium (protonated L-alanine)." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 3 H 7 N 1 O 1"
xref	MassAvg: "73.09"
xref	MassMono: "73.052215"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.857. MOD:00857 N,N,N-trimethyl-L-alanine (from L-alaninium)

Table 859. Term [MOD:00857]
id	MOD:00857
name	N,N,N-trimethyl-L-alanine (from L-alaninium)
def	"A protein modification that effectively converts an L-alaninium (protonated L-alanine) residue to an N,N,N-trimethyl-L-alanine." [PubMed:12590383, PubMed:332162, PubMed:3979397, PubMed:6778808, PubMed:7715456, UniMod:37#A]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N2Me3+Ala process (MOD:00071) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N2Me3Ala" EXACT PSI-MOD-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 13 N 1 O 1"
xref	MassAvg: "115.18"
xref	MassMono: "115.099165"
xref	Origin: "MOD:00856"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01687 alpha-amino trimethylated residue ! alpha-amino trimethylated residue
relationship	derives_from MOD:00856 protonated L-alanine (L-alaninium) residue ! protonated L-alanine (L-alaninium) residue

2.858. MOD:00858 D-alanine (Ser)

Table 860. Term [MOD:00858]
id	MOD:00858
name	D-alanine (Ser)
def	"A protein modification that effectively converts an L-serine residue to D-alanine." [PubMed:7961627, RESID:AA0191#SER]
synonym	"®-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"D-Ala(Ser)" EXACT PSI-MOD-label []
synonym	"D-alanine" EXACT RESID-name []
synonym	"MOD_RES D-alanine (Ser)" EXACT UniProt-feature []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "C 0 H 0 N 0 O -1"
xref	DiffMono: "-15.994915"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00862 D-alanine ! D-alanine
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01161 deoxygenated residue ! deoxygenated residue

2.859. MOD:00859 modified residue that can arise from different natural residues

Table 861. Term [MOD:00859]
id	MOD:00859
name	modified residue that can arise from different natural residues
def	"A protein modification that can be derived from different natural residues by different chemical processes." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.860. MOD:00860 sulfur containing modified residue

Table 862. Term [MOD:00860]
id	MOD:00860
name	sulfur containing modified residue
def	"A protein modification that produces an amino acid residue containing an exogenous sulfur atom." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.861. MOD:00861 phosphorus containing modified residue

Table 863. Term [MOD:00861]
id	MOD:00861
name	phosphorus containing modified residue
def	"A protein modification that produces an amino acid residue containing a phosphorus atom." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.862. MOD:00862 D-alanine

Table 864. Term [MOD:00862]
id	MOD:00862
name	D-alanine
def	"A protein modification that effectively converts a source amino acid residue to D-alanine." [ChEBI:29949, PubMed:7287302, PubMed:7961627, RESID:AA0191]
synonym	"®-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"D-alanine" EXACT RESID-name []
synonym	"MOD_RES D-alanine (Ala)" EXACT UniProt-feature []
synonym	"MOD_RES D-alanine (Ser)" EXACT UniProt-feature []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.863. MOD:00863 D-allo-threonine

Table 865. Term [MOD:00863]
id	MOD:00863
name	D-allo-threonine
def	"A protein modification that effectively converts an L-threonine residue to D-allo-threonine." [ChEBI:32826, PubMed:18025465, PubMed:6893271, RESID:AA0199]
synonym	"(2R,3R)-2-amino-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"D-Thr" EXACT PSI-MOD-label []
synonym	"D-threonine" EXACT RESID-name []
synonym	"MOD_RES D-threonine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 7 N 1 O 2"
xref	MassAvg: "101.10"
xref	MassMono: "101.047678"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.864. MOD:00864 tris-L-cysteinyl L-histidino diiron disulfide

Table 866. Term [MOD:00864]
id	MOD:00864
name	tris-L-cysteinyl L-histidino diiron disulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-histidine residue and a two-iron two-sulfur cluster to tris-L-cysteinyl L-histidino diiron disulfide." [PubMed:17766439, PubMed:17766440, RESID:AA0438]
comment	Cross-link 4.
synonym	"CDGSH domain iron-sulfur cluster" EXACT RESID-alternate []
synonym	"di-mu-sulfido(bis-S-cysteinyliron)(S-cysteinyl-N3'-histidinoiron)" EXACT RESID-systematic []
synonym	"METAL Iron-sulfur (2Fe-2S)" EXACT UniProt-feature []
synonym	"METAL Iron-sulfur (2Fe-2S); via pros nitrogen" EXACT UniProt-feature []
synonym	"tris-L-cysteinyl L-histidino diiron disulfide" EXACT RESID-name []
xref	DiffAvg: "171.78"
xref	DiffFormula: "C 0 Fe 2 H -4 N 0 O 0 S 2"
xref	DiffMono: "171.783814"
xref	FormalCharge: "2-"
xref	Formula: "C 15 Fe 2 H 18 N 6 O 4 S 5"
xref	MassAvg: "618.34"
xref	MassMono: "617.870280"
xref	Origin: "C, C, C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.865. MOD:00865 N-aspartyl-glycosylsphingolipidinositolethanolamine

Table 867. Term [MOD:00865]
id	MOD:00865
name	N-aspartyl-glycosylsphingolipidinositolethanolamine
def	"A protein modification that effectively converts an L-aspartic acid residue to N-aspartyl-glycosylsphingolipidinositolethanolamine." [RESID:AA0439]
synonym	"GSIAsp" EXACT PSI-MOD-label []
synonym	"LIPID GPI-like-anchor amidated aspartate" EXACT UniProt-feature []
synonym	"N-aspartyl-glycosylsphingolipidinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 6 H 12 N 2 O 7 P 1"
xref	MassAvg: "255.14"
xref	MassMono: "255.038212"
xref	Origin: "D"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00466 glycosylsphingolipidinositolated residue ! glycosylsphingolipidinositolated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.866. MOD:00866 dihydroxylated proline

Table 868. Term [MOD:00866]
id	MOD:00866
name	dihydroxylated proline
def	"A protein modification that effectively converts an L-proline residue to one of several dihydroxylated proline residues, such as (2S,3R,4R)-3,4-dihydroxyproline or (2S,3R,4S)-3,4-dihydroxyproline." [PubMed:18688235]
synonym	"Hy2Pro" EXACT PSI-MOD-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:00678 hydroxylated proline ! hydroxylated proline

2.867. MOD:00867 L-cysteinyl-L-selenocysteine (Cys-Cys)

Table 869. Term [MOD:00867]
id	MOD:00867
name	L-cysteinyl-L-selenocysteine (Cys-Cys)
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-cysteine converted to an L-selenocysteine residue to form L-cysteinyl-L-selenocystine." [PubMed:10801974, PubMed:12911312, PubMed:17177418, RESID:AA0358#CYS]
comment	Cross-link 2.
synonym	"(R,R)-2-amino-3-[3-(2-aminopropanoic acid)sulfanyl]selanylpropanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Cysteinyl-selenocysteine (Cys-Sec)" EXACT UniProt-feature []
synonym	"CROSSLNK Cysteinyl-selenocysteine (Sec-Cys)" EXACT UniProt-feature []
synonym	"L-cysteinyl-L-selenocysteine" EXACT RESID-name []
xref	DiffAvg: "44.90"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S -1 Se 1"
xref	DiffMono: "45.928800"
xref	Formula: "C 6 H 8 N 2 O 2 S 1 Se 1"
xref	MassAvg: "251.17"
xref	MassMono: "251.947170"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00007 selenium substitution for sulfur ! selenium substitution for sulfur
is_a	MOD:01627 L-cysteinyl-L-selenocysteine ! L-cysteinyl-L-selenocysteine

2.868. MOD:00868 natural, non-standard encoded residue

Table 870. Term [MOD:00868]
id	MOD:00868
name	natural, non-standard encoded residue
def	"A protein modification that inserts or replaces a residue with a natural, non-standard encoded residue, such as N-formyl-L-methionine, L-selenocysteine, or L-pyrrolysine." [PubMed:18688235]
comment	These are produced exclusively by modification of amino acids acylated to special tRNA before incorporation by ribosomes into proteins. For this reason, they have also been referred to as pre-translational modifications.
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "natural"
is_a	MOD:00009 natural residue ! natural residue

2.869. MOD:00869 L-alanine residue (Asp)

Table 871. Term [MOD:00869]
id	MOD:00869
name	L-alanine residue (Asp)
def	"A protein modification that effectively converts an L-aspartic acid residue to L-alanine." [PubMed:17138938, RESID:AA0001#ASP]
comment	This has been reported to occur by a natural process of beta-decarboxylation.
synonym	"(2S)-2-aminopropanoic acid" EXACT RESID-systematic []
synonym	"2-aminopropionic acid" EXACT RESID-alternate []
synonym	"2-azanylpropanoic acid" EXACT RESID-alternate []
synonym	"alpha-alanine" EXACT RESID-alternate []
synonym	"alpha-aminopropionic acid" EXACT RESID-alternate []
synonym	"Asp(Ala)" EXACT PSI-MOD-label []
synonym	"L-alanine" EXACT RESID-name []
synonym	"MOD_RES Beta-decarboxylated aspartate" EXACT UniProt-feature []
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "C 3 H 5 N 1 O 1"
xref	MassAvg: "71.08"
xref	MassMono: "71.037114"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00010 L-alanine residue ! L-alanine residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.870. MOD:00870 phenyl isocyanate derivatized residue

Table 872. Term [MOD:00870]
id	MOD:00870
name	phenyl isocyanate derivatized residue
def	"A protein modification produced by formation of an adduct with phenyl isocyanate." [UniMod:411]
comment	From UniMod with no citation.
subset	PSI-MOD-slim
synonym	"phenyl isocyanate" RELATED UniMod-description []
synonym	"Phenylisocyanate" RELATED PSI-MS-label []
xref	DiffAvg: "119.12"
xref	DiffFormula: "C 7 H 5 N 1 O 1"
xref	DiffMono: "119.037114"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00840 isocyanate reagent derivatized residue ! isocyanate reagent derivatized residue

2.871. MOD:00871 (2)H5-phenyl isocyanate derivatized residue

Table 873. Term [MOD:00871]
id	MOD:00871
name	(2)H5-phenyl isocyanate derivatized residue
def	"A protein modification produced by formation of an adduct with (2)H5-phenyl isocyanate." [UniMod:412]
comment	From UniMod with no citation.
subset	PSI-MOD-slim
synonym	"d5-phenyl isocyanate" RELATED UniMod-description []
synonym	"Phenylisocyanate:2H(5)" RELATED PSI-MS-label []
xref	DiffAvg: "124.07"
xref	DiffFormula: "C 7 (2)H 5 N 1 O 1"
xref	DiffMono: "124.068498"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00870 phenyl isocyanate derivatized residue ! phenyl isocyanate derivatized residue
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.872. MOD:00872 L-isoglutamyl monoglutamic acid

Table 874. Term [MOD:00872]
id	MOD:00872
name	L-isoglutamyl monoglutamic acid
def	"OBSOLETE because redundant and identical to MOD:01970. Remap to MOD:01970." [PubMed:10747868, PubMed:15525938, PubMed:1680872, RESID:AA0202#var, UniMod:450]
synonym	"Glu" RELATED UniMod-interim []
synonym	"monoglutamyl" RELATED UniMod-description []
synonym	"N alpha -(gamma-Glutamyl)-Glu" EXACT DeltaMass-label []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 10 H 14 N 2 O 6"
xref	MassAvg: "258.23"
xref	MassMono: "258.085186"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.873. MOD:00873 L-isoglutamyl diglutamic acid

Table 875. Term [MOD:00873]
id	MOD:00873
name	L-isoglutamyl diglutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to isoglutamyl glutamyl-glutamic acid, forming an isopeptide bond with a diglutamic acid." [DeltaMass:0, PubMed:10747868, PubMed:1680872, RESID:AA0202#var, UniMod:451]
synonym	"diglutamyl" RELATED UniMod-description []
synonym	"GluGlu" RELATED UniMod-interim []
xref	DiffAvg: "258.23"
xref	DiffFormula: "C 10 H 14 N 2 O 6"
xref	DiffMono: "258.085186"
xref	Formula: "C 15 H 21 N 3 O 9"
xref	MassAvg: "387.35"
xref	MassMono: "387.127779"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00207 L-isoglutamyl-polyglutamic acid ! L-isoglutamyl-polyglutamic acid

2.874. MOD:00874 L-isoglutamyl triglutamic acid

Table 876. Term [MOD:00874]
id	MOD:00874
name	L-isoglutamyl triglutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to isoglutamyl glutamyl-glutamyl-glutamic acid, forming an isopeptide bond with a triglutamic acid." [DeltaMass:0, PubMed:10747868, PubMed:1680872, RESID:AA0202#var, UniMod:452]
comment	From DeltaMass: Average Mass: 388.
synonym	"GluGluGlu" RELATED UniMod-interim []
synonym	"N alpha -(gamma-Glutamyl)-Glu3" EXACT DeltaMass-label []
synonym	"triglutamyl" RELATED UniMod-description []
xref	DiffAvg: "387.35"
xref	DiffFormula: "C 15 H 21 N 3 O 9"
xref	DiffMono: "387.127779"
xref	Formula: "C 20 H 28 N 4 O 12"
xref	MassAvg: "516.46"
xref	MassMono: "516.170372"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00207 L-isoglutamyl-polyglutamic acid ! L-isoglutamyl-polyglutamic acid

2.875. MOD:00875 L-isoglutamyl tetraglutamic acid

Table 877. Term [MOD:00875]
id	MOD:00875
name	L-isoglutamyl tetraglutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to isoglutamyl glutamyl-glutamyl-glutamyl-glutamic acid, forming an isopeptide bond with a tetraglutamic acid." [PubMed:10747868, PubMed:1680872, RESID:AA0202#var, UniMod:453]
synonym	"GluGluGluGlu" RELATED UniMod-interim []
synonym	"tetraglutamyl" RELATED UniMod-description []
xref	DiffAvg: "516.46"
xref	DiffFormula: "C 20 H 28 N 4 O 12"
xref	DiffMono: "516.170372"
xref	Formula: "C 25 H 35 N 5 O 15"
xref	MassAvg: "645.57"
xref	MassMono: "645.212965"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00207 L-isoglutamyl-polyglutamic acid ! L-isoglutamyl-polyglutamic acid

2.876. MOD:00876 hexosaminylated residue

Table 878. Term [MOD:00876]
id	MOD:00876
name	hexosaminylated residue
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a hexosamine sugar group through a glycosidic bond." [UniMod:454]
synonym	"HexN" RELATED PSI-MS-label []
synonym	"Hexosamine" RELATED UniMod-description []
synonym	"Hexosamines (GalN, GlcN)" EXACT DeltaMass-label []
xref	DiffAvg: "161.16"
xref	DiffFormula: "C 6 H 11 N 1 O 4"
xref	DiffMono: "161.068808"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.877. MOD:00877 imidoester crosslink dimethyl pimelimidate singly attached

Table 879. Term [MOD:00877]
id	MOD:00877
name	imidoester crosslink dimethyl pimelimidate singly attached
def	"dimethyl pimelimidate modification from UniMod" [UniMod:455, URL:http\://www.piercenet.com/files/0668ss5.pdf]
synonym	"One end of crosslink attached, one end free" RELATED UniMod-description []
synonym	"Xlink:DMP-s" RELATED UniMod-interim []
xref	DiffAvg: "154.21"
xref	DiffFormula: "C 8 H 14 N 2 O 1"
xref	DiffMono: "154.110613"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.878. MOD:00878 imidoester crosslink dimethyl pimelimidate doubly attached

Table 880. Term [MOD:00878]
id	MOD:00878
name	imidoester crosslink dimethyl pimelimidate doubly attached
def	"dimethyl pimelimidate modification from UniMod - Mechanism of the reaction of imidoesters with amines" [PubMed:7171546, UniMod:456, URL:http\://dx.doi.org/10.1021/ja00877a017]
synonym	"Both ends of crosslink attached to same peptide" RELATED UniMod-description []
synonym	"Xlink:DMP" RELATED UniMod-interim []
xref	DiffAvg: "122.17"
xref	DiffFormula: "C 7 H 10 N 2"
xref	DiffMono: "122.084398"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.879. MOD:00879 naphthalene-2,3-dicarboxaldehyde

Table 881. Term [MOD:00879]
id	MOD:00879
name	naphthalene-2,3-dicarboxaldehyde
def	"modification from UniMod" [PubMed:2081203, UniMod:457]
synonym	"naphthalene-2,3-dicarboxaldehyde" RELATED UniMod-description []
synonym	"NDA" RELATED UniMod-interim []
xref	DiffAvg: "175.19"
xref	DiffFormula: "C 13 H 5 N 1"
xref	DiffMono: "175.042199"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.880. MOD:00880 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue

Table 882. Term [MOD:00880]
id	MOD:00880
name	6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue
def	"A protein modification produced by formation of an adduct with 6x(13)C labeled 4-sulfophenyl isothiocyanate." [PubMed:15536630, PubMed:16526082, UniMod:464]
synonym	"4-sulfophenyl isothiocyanate (Heavy C13)" RELATED UniMod-description []
synonym	"SPITC:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "220.99"
xref	DiffFormula: "(12)C 1 (13)C 6 H 5 N 1 O 3 S 2"
xref	DiffMono: "220.991214"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00584 4-sulfophenyl isothiocyanate derivatized residue ! 4-sulfophenyl isothiocyanate derivatized residue
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent

2.881. MOD:00881 N-reductive amination-D

Table 883. Term [MOD:00881]
id	MOD:00881
name	N-reductive amination-D
def	"OBSOLETE because UniMod entry 465 megerd with 199. Remap to MOD:00552 DiMethyl-CH2D." [PubMed:9252331, UniMod:465]
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 2 (2)H 4"
xref	DiffMono: "32.056407"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.882. MOD:00882 S-(2-aminoethyl)cysteine (Ser)

Table 884. Term [MOD:00882]
id	MOD:00882
name	S-(2-aminoethyl)cysteine (Ser)
def	"A protein modification that effectively converts an L-serine residue to S-(2-aminoethyl)cysteine." [DeltaMass:171, PubMed:12923550, UniMod:472#S]
comment	From DeltaMass: Average Mass: 146 Abbreviation:-AECys_ Formula:C5H10O2N1S1 Monoisotopic Mass Change:146.051 Average Mass Change:146.214 References:PE Sciex.
synonym	"AEC-MAEC" RELATED UniMod-interim []
synonym	"Aminoethyl Cysteinyl (AECys)" EXACT DeltaMass-label []
synonym	"aminoethylcysteine" RELATED UniMod-description []
xref	DiffAvg: "59.13"
xref	DiffFormula: "C 2 H 5 N 1 O -1 S 1"
xref	DiffMono: "59.019356"
xref	Formula: "C 5 H 10 N 2 O 1 S 1"
xref	MassAvg: "146.21"
xref	MassMono: "146.051384"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.883. MOD:00883 C1-amidated residue

Table 885. Term [MOD:00883]
id	MOD:00883
name	C1-amidated residue
def	"A protein modification that effectively replaces a 1-carboxyl group (usually referred to as the alpha-carboxyl) with a carboxamido group." [DeltaMass:0, OMSSA:25, UniMod:2]
comment	The normal biological process involves formation of an amide of an amino acid residue in a peptide sequence where it is followed by a glycine and two basic residues, either arginine or lysine, although in some taxa only one basic residue is required. The peptide is cleaved after the basic residues, glycine is oxidized to hydroxyglycine, which decomposes to release a carboxamide C-terminal [JSG].
subset	PSI-MOD-slim
synonym	"alpha-amidated residue" EXACT PSI-MOD-alternate []
synonym	"Amidated" RELATED PSI-MS-label []
synonym	"Amidation" RELATED UniMod-description []
synonym	"Amide formation (C terminus)" EXACT DeltaMass-label []
synonym	"ctermamide" EXACT OMSSA-label []
synonym	"ResN" EXACT PSI-MOD-label []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00674 amidated residue ! amidated residue

2.884. MOD:00884 S-aminoethylcysteine (Cys)

Table 886. Term [MOD:00884]
id	MOD:00884
name	S-aminoethylcysteine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to S-2-aminoethylcysteine." [PubMed:1175632, PubMed:18688235]
comment	This modified residue is a chemical isolog of L-lysine for trypsin hydolysis produced from L-cysteine by aziridine.
subset	PSI-MOD-slim
synonym	"4-thialysine" EXACT PSI-MOD-alternate []
synonym	"L-cysteine aziridine adduct" EXACT PSI-MOD-alternate []
synonym	"S-(2-aminoethyl)-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "43.07"
xref	DiffFormula: "C 2 H 5 N 1 O 0 S 0"
xref	DiffMono: "43.042199"
xref	Formula: "C 5 H 10 N 2 O 1 S 1"
xref	MassAvg: "146.21"
xref	MassMono: "146.051384"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.885. MOD:00885 ester crosslinked residues

Table 887. Term [MOD:00885]
id	MOD:00885
name	ester crosslinked residues
def	"A protein modification that crosslinks two residues by formation of an ester bond." [PubMed:18688235]
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.886. MOD:00886 6'-chloro-L-tryptophan

Table 888. Term [MOD:00886]
id	MOD:00886
name	6'-chloro-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 6'-chloro-L-tryptophan." [PubMed:9033387, RESID:AA0180, UniMod:936#W]
comment	The UniMod:340 cross-reference to RESID:AA0180 is incorrect. RESID:AA0180 should be cross-referenced by UniMod:936 [JSG].
synonym	"(2S)-2-amino-3-(6-chloro-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"6'-chloro-L-tryptophan" EXACT RESID-name []
synonym	"6'-ClTrp" EXACT PSI-MOD-label []
synonym	"MOD_RES 6'-chlorotryptophan" EXACT UniProt-feature []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 11 Cl 1 H 9 N 2 O 1"
xref	MassAvg: "220.66"
xref	MassMono: "220.040341"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01913 monochlorinated L-tryptophan ! monochlorinated L-tryptophan

2.887. MOD:00887 methylated aspartic acid

Table 889. Term [MOD:00887]
id	MOD:00887
name	methylated aspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to a methylated aspartic acid, such as aspartic acid 4-methyl ester." [PubMed:18688235]
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.888. MOD:00888 protonated L-proline (L-prolinium) residue

Table 890. Term [MOD:00888]
id	MOD:00888
name	protonated L-proline (L-prolinium) residue
def	"A protein modification that effectively converts an L-proline to an L-prolinium (protonated L-proline)." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 1 O 1"
xref	MassAvg: "99.13"
xref	MassMono: "99.067865"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.889. MOD:00889 N,N-dimethyl-L-proline (from L-prolinium)

Table 891. Term [MOD:00889]
id	MOD:00889
name	N,N-dimethyl-L-proline (from L-prolinium)
def	"A protein modification that effectively converts an L-prolinium (charged L-proline) residue to N,N-dimethyl-L-proline." [UniMod:36#P]
subset	PSI-MOD-slim
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.030752"
xref	FormalCharge: "1+"
xref	Formula: "C 7 H 13 N 1 O 1"
xref	MassAvg: "127.19"
xref	MassMono: "127.099165"
xref	Origin: "MOD:00888"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00075 N,N-dimethyl-L-proline ! N,N-dimethyl-L-proline
relationship	derives_from MOD:00888 protonated L-proline (L-prolinium) residue ! protonated L-proline (L-prolinium) residue

2.890. MOD:00890 phosphorylated L-histidine

Table 892. Term [MOD:00890]
id	MOD:00890
name	phosphorylated L-histidine
def	"A protein modification that effectively converts an L-histidine residue to a phosphorylated L-histidine, such as pros-phosphohistidine, or tele-phosphohistidine." [OMSSA:192, UniMod:21#H]
subset	PSI-MOD-slim
synonym	"mod192" EXACT OMSSA-label []
synonym	"NPhosHis" EXACT PSI-MOD-label []
synonym	"Phospho" RELATED PSI-MS-label []
synonym	"phosphohistidine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 6 H 8 N 3 O 4 P 1"
xref	MassAvg: "217.12"
xref	MassMono: "217.025242"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01456 N-phosphorylated residue ! N-phosphorylated residue

2.891. MOD:00891 D-serine

Table 893. Term [MOD:00891]
id	MOD:00891
name	D-serine
def	"A protein modification that effectively converts a source amino acid residue to D-serine." [ChEBI:29998, PubMed:6893271, PubMed:7973665, RESID:AA0195]
synonym	"®-2-amino-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"D-Ser" EXACT PSI-MOD-label []
synonym	"D-serine" EXACT RESID-name []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 5 N 1 O 2"
xref	MassAvg: "87.08"
xref	MassMono: "87.032028"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.892. MOD:00892 D-serine (Cys)

Table 894. Term [MOD:00892]
id	MOD:00892
name	D-serine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to D-serine." [PubMed:18025465, PubMed:6893271, RESID:AA0195#CYS]
synonym	"®-2-amino-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"D-serine" EXACT RESID-name []
xref	DiffAvg: "-16.06"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S -1"
xref	DiffMono: "-15.977156"
xref	Formula: "C 3 H 5 N 1 O 2"
xref	MassAvg: "87.08"
xref	MassMono: "87.032028"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00891 D-serine ! D-serine
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.893. MOD:00893 residues isobaric at 128.0-128.1

Table 895. Term [MOD:00893]
id	MOD:00893
name	residues isobaric at 128.0-128.1
def	"Natural or modified residues with a mass of 128.0-128.1 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00616 residues isobaric at a resolution below 0.1 Da ! residues isobaric at a resolution below 0.1 Da

2.894. MOD:00894 residues isobaric at 128.058578 Da

Table 896. Term [MOD:00894]
id	MOD:00894
name	residues isobaric at 128.058578 Da
def	"Natural or modified resiues with a mass of 128.058578 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00569 residues isobaric at a resolution below 0.000001 Da ! residues isobaric at a resolution below 0.000001 Da
is_a	MOD:00893 residues isobaric at 128.0-128.1 ! residues isobaric at 128.0-128.1

2.895. MOD:00895 FAD modified residue

Table 897. Term [MOD:00895]
id	MOD:00895
name	FAD modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a flavin adenine dinucleotide (FAD) group." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00697 flavin modified residue ! flavin modified residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.896. MOD:00896 FMN modified residue

Table 898. Term [MOD:00896]
id	MOD:00896
name	FMN modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a riboflavin phosphate (flavin mononucleotide, FMN) group." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00697 flavin modified residue ! flavin modified residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.897. MOD:00897 N-acetyl-S-archeol-cysteine

Table 899. Term [MOD:00897]
id	MOD:00897
name	N-acetyl-S-archeol-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-acetyl-S-archeol-L-cysteine." [RESID:AA0043#var, RESID:AA0223#var]
xref	DiffAvg: "677.20"
xref	DiffFormula: "C 45 H 88 N 0 O 3 S 0"
xref	DiffMono: "676.673347"
xref	Formula: "C 48 H 93 N 1 O 4 S 1"
xref	MassAvg: "780.34"
xref	MassMono: "779.682531"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	has_functional_parent MOD:00052 N-acetyl-L-cysteine ! N-acetyl-L-cysteine
relationship	has_functional_parent MOD:00228 S-diphytanylglycerol diether-L-cysteine ! S-diphytanylglycerol diether-L-cysteine

2.898. MOD:00898 S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine

Table 900. Term [MOD:00898]
id	MOD:00898
name	S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine." [PubMed:10896212, PubMed:4575979, PubMed:9056182, RESID:AA0107#var, UniMod:377]
comment	Incidental to RESID:AA0060.
synonym	"Diacylglycerol" RELATED PSI-MS-label []
synonym	"diacylglycerol" RELATED UniMod-description []
xref	DiffAvg: "576.95"
xref	DiffFormula: "C 37 H 68 N 0 O 4 S 0"
xref	DiffMono: "576.511761"
xref	Formula: "C 40 H 73 N 1 O 5 S 1"
xref	MassAvg: "680.09"
xref	MassMono: "679.520945"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00116 S-diacylglycerol-L-cysteine ! S-diacylglycerol-L-cysteine

2.899. MOD:00899 N-palmitoyl-S-diacylglycerol-L-cysteine

Table 901. Term [MOD:00899]
id	MOD:00899
name	N-palmitoyl-S-diacylglycerol-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-S-diacylglycerol-L-cysteine." [RESID:AA0069#var, RESID:AA0107#var]
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	has_functional_parent MOD:00069 N-palmitoyl-L-cysteine ! N-palmitoyl-L-cysteine
relationship	has_functional_parent MOD:00116 S-diacylglycerol-L-cysteine ! S-diacylglycerol-L-cysteine

2.900. MOD:00900 N-palmitoyl-S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine

Table 902. Term [MOD:00900]
id	MOD:00900
name	N-palmitoyl-S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine." [PubMed:18688235]
synonym	"®-2-hexadecanoylamino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]sulfanylpropanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-hexadecanoylamino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]thiopropanoic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "815.36"
xref	DiffFormula: "C 53 H 98 N 0 O 5 S 0"
xref	DiffMono: "814.741426"
xref	Formula: "C 56 H 103 N 1 O 6 S 1"
xref	MassAvg: "918.50"
xref	MassMono: "917.750611"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00899 N-palmitoyl-S-diacylglycerol-L-cysteine ! N-palmitoyl-S-diacylglycerol-L-cysteine
relationship	has_functional_parent MOD:00069 N-palmitoyl-L-cysteine ! N-palmitoyl-L-cysteine
relationship	has_functional_parent MOD:00898 S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine ! S-(sn-1-2-oleoyl-3-palmitoyl-glycerol)cysteine

2.901. MOD:00901 modified L-alanine residue

Table 903. Term [MOD:00901]
id	MOD:00901
name	modified L-alanine residue
def	"A protein modification that modifies an L-alanine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModAla" EXACT PSI-MOD-label []
xref	Origin: "A"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.902. MOD:00902 modified L-arginine residue

Table 904. Term [MOD:00902]
id	MOD:00902
name	modified L-arginine residue
def	"A protein modification that modifies an L-arginine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModArg" EXACT PSI-MOD-label []
xref	Origin: "R"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.903. MOD:00903 modified L-asparagine residue

Table 905. Term [MOD:00903]
id	MOD:00903
name	modified L-asparagine residue
def	"A protein modification that modifies an L-asparagine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModAsn" EXACT PSI-MOD-label []
xref	Origin: "N"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.904. MOD:00904 modified L-aspartic acid residue

Table 906. Term [MOD:00904]
id	MOD:00904
name	modified L-aspartic acid residue
def	"A protein modification that modifies an L-aspartic acid residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModAsp" EXACT PSI-MOD-label []
xref	Origin: "D"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.905. MOD:00905 modified L-cysteine residue

Table 907. Term [MOD:00905]
id	MOD:00905
name	modified L-cysteine residue
def	"A protein modification that modifies an L-cysteine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModCys" EXACT PSI-MOD-label []
xref	Origin: "C"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.906. MOD:00906 modified L-glutamic acid residue

Table 908. Term [MOD:00906]
id	MOD:00906
name	modified L-glutamic acid residue
def	"A protein modification that modifies an L-glutamic acid residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModGlu" EXACT PSI-MOD-label []
xref	Origin: "E"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.907. MOD:00907 modified L-glutamine residue

Table 909. Term [MOD:00907]
id	MOD:00907
name	modified L-glutamine residue
def	"A protein modification that modifies an L-glutamine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModGln" EXACT PSI-MOD-label []
xref	Origin: "Q"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.908. MOD:00908 modified glycine residue

Table 910. Term [MOD:00908]
id	MOD:00908
name	modified glycine residue
def	"A protein modification that modifies a glycine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModGly" EXACT PSI-MOD-label []
xref	Origin: "G"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.909. MOD:00909 modified L-histidine residue

Table 911. Term [MOD:00909]
id	MOD:00909
name	modified L-histidine residue
def	"A protein modification that modifies an L-histidine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModHis" EXACT PSI-MOD-label []
xref	Origin: "H"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.910. MOD:00910 modified L-isoleucine residue

Table 912. Term [MOD:00910]
id	MOD:00910
name	modified L-isoleucine residue
def	"A protein modification that modifies an L-isoleucine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModIle" EXACT PSI-MOD-label []
xref	Origin: "I"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.911. MOD:00911 modified L-leucine residue

Table 913. Term [MOD:00911]
id	MOD:00911
name	modified L-leucine residue
def	"A protein modification that modifies an L-leucine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModLeu" EXACT PSI-MOD-label []
xref	Origin: "L"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.912. MOD:00912 modified L-lysine residue

Table 914. Term [MOD:00912]
id	MOD:00912
name	modified L-lysine residue
def	"A protein modification that modifies an L-lysine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModLys" EXACT PSI-MOD-label []
xref	Origin: "K"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.913. MOD:00913 modified L-methionine residue

Table 915. Term [MOD:00913]
id	MOD:00913
name	modified L-methionine residue
def	"A protein modification that modifies an L-methionine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModMet" EXACT PSI-MOD-label []
xref	Origin: "M"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.914. MOD:00914 modified L-phenylalanine residue

Table 916. Term [MOD:00914]
id	MOD:00914
name	modified L-phenylalanine residue
def	"A protein modification that modifies an L-phenylalanine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModPhe" EXACT PSI-MOD-label []
xref	Origin: "F"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.915. MOD:00915 modified L-proline residue

Table 917. Term [MOD:00915]
id	MOD:00915
name	modified L-proline residue
def	"A protein modification that modifies an L-proline residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModPro" EXACT PSI-MOD-label []
xref	Origin: "P"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.916. MOD:00916 modified L-serine residue

Table 918. Term [MOD:00916]
id	MOD:00916
name	modified L-serine residue
def	"A protein modification that modifies an L-serine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModSer" EXACT PSI-MOD-label []
xref	Origin: "S"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.917. MOD:00917 modified L-threonine residue

Table 919. Term [MOD:00917]
id	MOD:00917
name	modified L-threonine residue
def	"A protein modification that modifies an L-threonine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModThr" EXACT PSI-MOD-label []
xref	Origin: "T"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.918. MOD:00918 modified L-tryptophan residue

Table 920. Term [MOD:00918]
id	MOD:00918
name	modified L-tryptophan residue
def	"A protein modification that modifies an L-tryptophan residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModTrp" EXACT PSI-MOD-label []
xref	Origin: "W"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.919. MOD:00919 modified L-tyrosine residue

Table 921. Term [MOD:00919]
id	MOD:00919
name	modified L-tyrosine residue
def	"A protein modification that modifies an L-tyrosine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.920. MOD:00920 modified L-valine residue

Table 922. Term [MOD:00920]
id	MOD:00920
name	modified L-valine residue
def	"A protein modification that modifies an L-valine residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ModVal" EXACT PSI-MOD-label []
xref	Origin: "V"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified

2.921. MOD:00921 new uncategorized UniMod entries

Table 923. Term [MOD:00921]
id	MOD:00921
name	new uncategorized UniMod entries
def	"New uncategorized UniMod. OBSOLETE because organizational use is no longer required." [PubMed:18688235]
is_obsolete	true

2.922. MOD:00922 Cy3 CyDye DIGE Fluor saturation dye

Table 924. Term [MOD:00922]
id	MOD:00922
name	Cy3 CyDye DIGE Fluor saturation dye
def	"modification from UniMod Chemical derivative" [UniMod:494]
synonym	"Cy3 CyDye DIGE Fluor saturation dye" RELATED UniMod-description []
synonym	"CyDye-Cy3" RELATED UniMod-interim []
xref	DiffAvg: "672.84"
xref	DiffFormula: "C 37 H 44 N 4 O 6 S 1"
xref	DiffMono: "672.298156"
xref	Formula: "C 40 H 49 N 5 O 7 S 2"
xref	MassAvg: "775.98"
xref	MassMono: "775.307341"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.923. MOD:00923 Cy5 CyDye DIGE Fluor saturation dye

Table 925. Term [MOD:00923]
id	MOD:00923
name	Cy5 CyDye DIGE Fluor saturation dye
def	"modification from UniMod Chemical derivative" [UniMod:495]
synonym	"Cy5 CyDye DIGE Fluor saturation dye" RELATED UniMod-description []
synonym	"CyDye-Cy5" RELATED UniMod-interim []
xref	DiffAvg: "684.85"
xref	DiffFormula: "C 38 H 44 N 4 O 6 S 1"
xref	DiffMono: "684.298156"
xref	Formula: "C 41 H 49 N 5 O 7 S 2"
xref	MassAvg: "787.99"
xref	MassMono: "787.307341"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.924. MOD:00924 N6-(L-threonyl)-L-lysine

Table 926. Term [MOD:00924]
id	MOD:00924
name	N6-(L-threonyl)-L-lysine
def	"A protein modification that effectively crosslinks an L-lysine residue and an L-threonine residue by an isopeptide bond to form N6-(L-threonyl)-L-lysine." [PubMed:18063774, RESID:AA0440]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(2S,3R)-2-amino-3-hydroxybutanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"N6-(L-threonyl)-L-lysine" EXACT RESID-name []
synonym	"N6-threonyl-lysine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 10 H 18 N 3 O 3"
xref	MassAvg: "228.27"
xref	MassMono: "228.134816"
xref	Origin: "K, T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.925. MOD:00925 heptosylated residue

Table 927. Term [MOD:00925]
id	MOD:00925
name	heptosylated residue
def	"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a heptose sugar group through a glycosidic bond." [UniMod:490]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00693 glycosylated residue ! glycosylated residue

2.926. MOD:00926 Bisphenol A diglycidyl ether derivative

Table 928. Term [MOD:00926]
id	MOD:00926
name	Bisphenol A diglycidyl ether derivative
def	"Modification from UniMod Non-standard residue. OBSOLETE because not an amino acid modification. From UniMod not an approved entry." [PubMed:11225353, UniMod:493]
synonym	"BADGE" RELATED UniMod-interim []
synonym	"Bisphenol A diglycidyl ether derivative" RELATED UniMod-description []
xref	DiffAvg: "340.42"
xref	DiffFormula: "C 21 H 24 O 4"
xref	DiffMono: "340.167459"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.927. MOD:00927 2x(13)C,4x(2)H labeled dimethylated residue

Table 929. Term [MOD:00927]
id	MOD:00927
name	2x(13)C,4x(2)H labeled dimethylated residue
def	"A protein modification that effectively replaces two hydrogen atoms of a residue containing common isotopes with two (13)C,3x(2)H labeled methyl groups to form a 2x(13)C,6x(2)H labeled dimethylated residue." [PubMed:16335955, PubMed:3802193, UniMod:510]
synonym	"DiMethyl-C13HD2" RELATED UniMod-description []
synonym	"Dimethyl:2H(4)13C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "34.06"
xref	DiffFormula: "(13)C 2 (2)H 4"
xref	DiffMono: "34.063117"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue

2.928. MOD:00928 [3-(2,5)-dioxopyrrolidin-1-yloxycarbonyl)-propyl]dimethyloctylammonium

Table 930. Term [MOD:00928]
id	MOD:00928
name	[3-(2,5)-dioxopyrrolidin-1-yloxycarbonyl)-propyl]dimethyloctylammonium
def	"modification from UniMod Chemical derivative" [PubMed:16771548, UniMod:513]
comment	Should have children for K and X-N-term [JSG].
synonym	"[3-(2,5)-Dioxopyrrolidin-1-yloxycarbonyl)-propyl]dimethyloctylammonium" RELATED UniMod-description []
synonym	"C8-QAT" RELATED UniMod-interim []
xref	DiffAvg: "227.39"
xref	DiffFormula: "C 14 H 29 N 1 O 1"
xref	DiffMono: "227.224915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.929. MOD:00929 lactose glycated lysine

Table 931. Term [MOD:00929]
id	MOD:00929
name	lactose glycated lysine
def	"A modification produced in a non-enzymatic reaction between a lactose carbonyl group and an L-lysine to form a Schiff-base or an Amadori ketosamine lysine adduct." [PubMed:9606156, UniMod:512]
comment	The term lactosylation used with this meaning is a misnomer [JSG].
synonym	"Hex(2)" RELATED UniMod-interim []
synonym	"Lactosylation" RELATED UniMod-description []
xref	DiffAvg: "342.30"
xref	DiffFormula: "C 12 H 22 O 11"
xref	DiffMono: "342.116212"
xref	Formula: "C 18 H 34 N 2 O 12"
xref	MassAvg: "470.47"
xref	MassMono: "470.211175"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00767 glycated residue ! glycated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.930. MOD:00930 propyl-NAG tyrosine adduct

Table 932. Term [MOD:00930]
id	MOD:00930
name	propyl-NAG tyrosine adduct
def	"tyrosine adduct with substrate analog inhibitor 1,2-dideoxy-2'-methyl-alpha-D-glucopyranoso-[2,1-d]-Delta2'-thiazoline." [PubMed:15795231, UniMod:514]
xref	DiffAvg: "232.27"
xref	DiffFormula: "C 9 H 14 N 1 O 4 S 1"
xref	DiffMono: "232.064354"
xref	Formula: "C 18 H 23 N 2 O 6 S 1"
xref	MassAvg: "395.45"
xref	MassMono: "395.127682"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.931. MOD:00931 Michael addition of t-butyl hydroxylated BHT (BHTOH) to C, H or K

Table 933. Term [MOD:00931]
id	MOD:00931
name	Michael addition of t-butyl hydroxylated BHT (BHTOH) to C, H or K
def	"modification from UniMod Other - BHTOH is formed upon metabolism of BHT with P450 enzymes. The BHTOH is further metabolized to its quinone methide (electrophile) which reacts with -SH and -NH2 groups" [PubMed:11085420, UniMod:498]
synonym	"BHTOH" RELATED UniMod-interim []
synonym	"Michael addition of t-butyl hydroxylated BHT (BHTOH) to C, H or K" RELATED UniMod-description []
xref	DiffAvg: "234.34"
xref	DiffFormula: "C 15 H 22 O 2"
xref	DiffMono: "234.161980"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.932. MOD:00932 IDBEST tag for quantitation

Table 934. Term [MOD:00932]
id	MOD:00932
name	IDBEST tag for quantitation
def	"modification from UniMod Isotopic label" [PubMed:11821862, UniMod:499]
synonym	"Heavy IDBEST tag for quantitation" RELATED UniMod-description []
synonym	"IGBP:13C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "298.02"
xref	DiffFormula: "Br 1 (12)C 10 (13)C 2 H 13 N 2 O 2"
xref	DiffMono: "298.022749"
xref	Formula: "Br 1 (12)C 13 (13)C 2 H 18 N 3 O 3 S 1"
xref	MassAvg: "401.03"
xref	MassMono: "401.031934"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.933. MOD:00933 methylglyoxal arginine adduct (+54 amu)

Table 935. Term [MOD:00933]
id	MOD:00933
name	methylglyoxal arginine adduct (+54 amu)
def	"modification from UniMod Chemical derivative - 5-hydro-5-methylimidazol-4-one, arginine methylglyoxal arginine adduct (+54 amu)" [UniMod:319#R]
comment	Ref. Uchida K, Sakai K, Itakura K, Osawa T, Toyokuni S. 1977. Protein modification by lipid peroxidation products: formation of malondialdehyde-derived N(epsilon)-(2-propenol)lysine in proteins. Arch Biochem Biophys. 346(1):45-52.
synonym	"Delta:H(2)C(3)O(1)" RELATED PSI-MS-label []
synonym	"MDA adduct +54" RELATED UniMod-description []
xref	DiffAvg: "54.05"
xref	DiffFormula: "C 3 H 2 O 1"
xref	DiffMono: "54.010565"
xref	Formula: "C 9 H 14 N 4 O 2"
xref	MassAvg: "210.24"
xref	MassMono: "210.111676"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00630 C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine. ! C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine.
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.934. MOD:00934 Levuglandinyl - arginine hydroxylactam adduct

Table 936. Term [MOD:00934]
id	MOD:00934
name	Levuglandinyl - arginine hydroxylactam adduct
def	"modification from UniMod Post-translational" [UniMod:506]
synonym	"Levuglandinyl - arginine hydroxylactam adduct" RELATED UniMod-description []
synonym	"LG-Hlactam-R" RELATED UniMod-interim []
xref	DiffAvg: "306.40"
xref	DiffFormula: "C 19 H 26 N -2 O 5"
xref	DiffMono: "306.171876"
xref	Formula: "C 25 H 38 N 2 O 6"
xref	MassAvg: "462.59"
xref	MassMono: "462.272987"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00846 levuglandinyl (prostaglandin H2) adduct ! levuglandinyl (prostaglandin H2) adduct
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.935. MOD:00935 methionine oxidation with neutral loss of 64 Da

Table 937. Term [MOD:00935]
id	MOD:00935
name	methionine oxidation with neutral loss of 64 Da
def	"Oxidation of methionine to methionine sulfoxide with neutral loss of CH3SOH." [PubMed:18688235, PubMed:9004526]
comment	Originally created from UniMod:507 that was later deleted.
xref	DiffAvg: "-64.10"
xref	DiffFormula: "C -1 H -4 N 0 O -1 S -1"
xref	DiffMono: "-63.998286"
xref	Formula: "C 4 H 5 N 1 O 1 S 0"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.936. MOD:00936 Levuglandinyl - hydroxylactam adduct, K and N-term

Table 938. Term [MOD:00936]
id	MOD:00936
name	Levuglandinyl - hydroxylactam adduct, K and N-term
def	"modification from UniMod Post-translational" [UniMod:504]
synonym	"Levuglandinyl - lysine hydroxylactam adduct" RELATED UniMod-description []
synonym	"LG-Hlactam-K" RELATED UniMod-interim []
xref	DiffAvg: "348.44"
xref	DiffFormula: "C 20 H 28 O 5"
xref	DiffMono: "348.193674"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00846 levuglandinyl (prostaglandin H2) adduct ! levuglandinyl (prostaglandin H2) adduct

2.937. MOD:00937 Levuglandinyl - arginine lactam adduct

Table 939. Term [MOD:00937]
id	MOD:00937
name	Levuglandinyl - arginine lactam adduct
def	"modification from UniMod Post-translational" [UniMod:505]
synonym	"Levuglandinyl - arginine lactam adduct" RELATED UniMod-description []
synonym	"LG-lactam-R" RELATED UniMod-interim []
xref	DiffAvg: "290.40"
xref	DiffFormula: "C 19 H 26 N -2 O 4"
xref	DiffMono: "290.176961"
xref	Formula: "C 25 H 38 N 2 O 5"
xref	MassAvg: "446.59"
xref	MassMono: "446.278072"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00846 levuglandinyl (prostaglandin H2) adduct ! levuglandinyl (prostaglandin H2) adduct
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.938. MOD:00938 Levuglandinyl - lactam adduct, K and N-term

Table 940. Term [MOD:00938]
id	MOD:00938
name	Levuglandinyl - lactam adduct, K and N-term
def	"modification from UniMod Post-translational" [PubMed:12590383, UniMod:503]
synonym	"Levuglandinyl - lysine lactam adduct" RELATED UniMod-description []
synonym	"LG-lactam-K" RELATED UniMod-interim []
xref	DiffAvg: "332.44"
xref	DiffFormula: "C 20 H 28 O 4"
xref	DiffMono: "332.198759"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00846 levuglandinyl (prostaglandin H2) adduct ! levuglandinyl (prostaglandin H2) adduct

2.939. MOD:00939 hydrolyzed N-methylmaleimide cysteine adduct

Table 941. Term [MOD:00939]
id	MOD:00939
name	hydrolyzed N-methylmaleimide cysteine adduct
def	"modification from UniMod Chemical derivative" [UniMod:500]
synonym	"Nmethylmaleimide+water" RELATED UniMod-interim []
synonym	"Nmethylmaleimidehydrolysis" RELATED UniMod-description []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 8 H 12 N 2 O 4 S 1"
xref	MassAvg: "232.25"
xref	MassMono: "232.051778"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.940. MOD:00940 3-methyl-2-pyridyl isocyanate derivatized residue

Table 942. Term [MOD:00940]
id	MOD:00940
name	3-methyl-2-pyridyl isocyanate derivatized residue
def	"A protein modification produced by formation of an adduct with 3-methyl-2-pyridyl isocyanate." [PubMed:11078590, UniMod:501]
synonym	"3-methyl-2-pyridyl isocyanate" RELATED UniMod-description []
synonym	"PyMIC" RELATED UniMod-interim []
xref	DiffAvg: "134.14"
xref	DiffFormula: "C 7 H 6 N 2 O 1"
xref	DiffMono: "134.048013"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00840 isocyanate reagent derivatized residue ! isocyanate reagent derivatized residue

2.941. MOD:00941 dehydropyrrolizidine alkaloid (dehydroretronecine) derivatized cysteine

Table 943. Term [MOD:00941]
id	MOD:00941
name	dehydropyrrolizidine alkaloid (dehydroretronecine) derivatized cysteine
def	"modification from UniMod Chemical derivative" [PubMed:12175151, UniMod:488]
synonym	"Dehydropyrrolizidine alkaloid (dehydroretronecine) on cysteines" RELATED UniMod-description []
synonym	"DHP" RELATED UniMod-interim []
xref	DiffAvg: "118.16"
xref	DiffFormula: "C 8 H 8 N 1"
xref	DiffMono: "118.065674"
xref	Formula: "C 11 H 13 N 2 S 1"
xref	MassAvg: "205.30"
xref	MassMono: "205.079944"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.942. MOD:00942 (4,4,5,5-(2)H4)-L-lysine

Table 944. Term [MOD:00942]
id	MOD:00942
name	(4,4,5,5-(2)H4)-L-lysine
def	"A protein modification that effectively substitutes four (1)H protium atoms with four (2)H deuterium atoms to produce (4,4,5,5-(2)H4)-L-lysine." [OMSSA:180, UniMod:481]
comment	For SILAC experiments.
synonym	"4,4,5,5-D4 Lysine" RELATED UniMod-description []
synonym	"4,4,5,5-tetradeuterolysine" EXACT PSI-MOD-alternate []
synonym	"Label:2H(4)" RELATED UniMod-interim []
synonym	"lys-2H4" EXACT OMSSA-label []
xref	DiffAvg: "4.03"
xref	DiffFormula: "(1)H -4 (2)H 4"
xref	DiffMono: "4.025107"
xref	Formula: "C 6 (1)H 8 (2)H 4 N 2 O 1"
xref	MassAvg: "132.12"
xref	MassMono: "132.120070"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00837 deuterium tetrasubstituted residue ! deuterium tetrasubstituted residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.943. MOD:00943 4-trimethylammoniumbutanoyl derivatized residue

Table 945. Term [MOD:00943]
id	MOD:00943
name	4-trimethylammoniumbutanoyl derivatized residue
def	"modification from UniMod Isotopic label" [PubMed:12643539, UniMod:476]
synonym	"4-trimethyllammoniumbutyryl-" RELATED UniMod-description []
synonym	"TMAB" RELATED UniMod-interim []
xref	DiffAvg: "128.19"
xref	DiffFormula: "C 7 H 14 N 1 O 1"
xref	DiffMono: "128.107539"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.944. MOD:00944 d9-4-trimethylammoniumbutanoyl derivatized residue

Table 946. Term [MOD:00944]
id	MOD:00944
name	d9-4-trimethylammoniumbutanoyl derivatized residue
def	"modification from UniMod Isotopic label" [UniMod:477]
synonym	"d9-4-trimethyllammoniumbutyryl-" RELATED UniMod-description []
synonym	"TMAB:2H(9)" RELATED UniMod-interim []
xref	DiffAvg: "137.16"
xref	DiffFormula: "C 7 (1)H 5 (2)H 9 N 1 O 1"
xref	DiffMono: "137.164030"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00943 4-trimethylammoniumbutanoyl derivatized residue ! 4-trimethylammoniumbutanoyl derivatized residue
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.945. MOD:00945 fluorescein-5-thiosemicarbazide adduct

Table 947. Term [MOD:00945]
id	MOD:00945
name	fluorescein-5-thiosemicarbazide adduct
def	"OBSOLETE because redundant and identical to MOD:00626. Remap to MOD:00626." [PubMed:18688235]
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.946. MOD:00946 crosslinked residues with loss of ammonia

Table 948. Term [MOD:00946]
id	MOD:00946
name	crosslinked residues with loss of ammonia
def	"A protein modification that crosslinks two residues with a covalent bond and the loss of ammonia." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.947. MOD:00947 DeltaMass

Table 949. Term [MOD:00947]
id	MOD:00947
name	DeltaMass
def	"Entries from DeltaMass see http://www.abrf.org/index.cfm/dm.home?AvgMass=all." [PubMed:18688235]
is_a	MOD:00032 uncategorized protein modification ! uncategorized protein modification

2.948. MOD:00948 5'-dephospho

Table 950. Term [MOD:00948]
id	MOD:00948
name	5'-dephospho
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: -79
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.949. MOD:00949 desmosine

Table 951. Term [MOD:00949]
id	MOD:00949
name	desmosine
def	"OBSOLETE because redundant and identical to MOD:01933. Remap to MOD:01933." [DeltaMass:0]
comment	From DeltaMass: Average Mass: -58
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.950. MOD:00950 decomposed carboxymethylated methionine

Table 952. Term [MOD:00950]
id	MOD:00950
name	decomposed carboxymethylated methionine
def	"modification from DeltaMass" [DeltaMass:3]
comment	From DeltaMass: Average Mass: -48 Average Mass Change:-48 References:Anal. Biochem. Vol 216 No.1 p141
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "M"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.951. MOD:00951 L-gamma-carboxyglutamic acid with neutral loss of carbon dioxide

Table 953. Term [MOD:00951]
id	MOD:00951
name	L-gamma-carboxyglutamic acid with neutral loss of carbon dioxide
def	"Covalent modification of a peptide or protein L-glutamic acid residue to gamma-carboxyglutamic acid with secondary loss of a neutral carbon dioxide molecular fragment." [DeltaMass:58]
comment	From DeltaMass: Average Mass: -44 Formula:CO2 Average Mass Change:-44 References:Nakamura T, Yu Z, Fainzilber M, Burlingame AL. Protein Sci (1996) 5, 524-530 Mass spectrometric-based revision of the structure of a cysteine-rich peptide toxin with gamma-carboxyglutamic acid, TxVIIA, from the sea snail, Conus textile. Notes: The elimination of CO2 will regenerate glutamate as if there was no modification. However, peaks appearing with an interval of 44 is quite characteristic. It would be noteworthy to remind that loss of 44 from a gamma-carboxyglutamate-containing peptide may be observed not only as a result of spontaneous decarboxylation but also as an artifact under some ionization conditions such as negative ion mode MALDI.
synonym	"d4CbxGlu" EXACT PSI-MOD-label []
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00015 L-glutamic acid residue ! L-glutamic acid residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00957 modified residue with neutral loss of carbon dioxide ! modified residue with neutral loss of carbon dioxide
is_a	MOD:00960 decarboxylated residue ! decarboxylated residue

2.952. MOD:00952 (2-aminosuccinimidyl)acetic acid (Asp)

Table 954. Term [MOD:00952]
id	MOD:00952
name	(2-aminosuccinimidyl)acetic acid (Asp)
def	"A protein modification that crosslinks an aspartic acid and the following glycine residue with the formation of (2-aminosuccinimidyl)acetic acid and the loss of a water molecule." [PubMed:10801322, RESID:AA0441#ASP]
comment	Cross-link 2; this cross-link is formed by the condensation of an aspartic acid residue with the alpha-amido of the following residue.
subset	PSI-MOD-slim
synonym	"(2-aminosuccinimidyl)acetic acid" EXACT RESID-name []
synonym	"(3-amino-2,5-dioxo-1-pyrrolidinyl)acetic acid" EXACT RESID-alternate []
synonym	"[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]acetic acid" EXACT RESID-systematic []
synonym	"anhydroaspartyl glycine" EXACT RESID-alternate []
synonym	"aspartimide glycine" EXACT RESID-alternate []
synonym	"CROSSLNK (2-aminosuccinimidyl)acetic acid (Asp-Gly)" EXACT UniProt-feature []
synonym	"N-(2-aminosuccinyl)glycine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "D, G"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01628 (2-aminosuccinimidyl)acetic acid ! (2-aminosuccinimidyl)acetic acid

2.953. MOD:00953 O-(L-isoglutamyl)-L-serine (Glu-Ser)

Table 955. Term [MOD:00953]
id	MOD:00953
name	O-(L-isoglutamyl)-L-serine (Glu-Ser)
def	"A protein modification that effectively crosslinks an L-glutamic acid residue and an L-serine residue by an ester bond and releasing water to form O-(L-isoglutamyl)-L-serine." [DeltaMass:0, PubMed:19035375, RESID:AA0597#ESX]
comment	Cross-link 2; From DeltaMass: with no citation.
synonym	"(2S)-2-amino-5-[(2S)-2-amino-2-carboxyethoxy]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK isoglutamyl serine ester (Ser-Glu)" EXACT UniProt-feature []
synonym	"O(beta)-(gamma-glutamyl)serine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-serine" EXACT RESID-name []
synonym	"O-gamma-Glutamyl- (Crosslink to Serine)" EXACT DeltaMass-label []
synonym	"O3-(isoglutamyl)-serine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 8 H 10 N 2 O 4"
xref	MassAvg: "198.18"
xref	MassMono: "198.064057"
xref	Origin: "E, S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01977 O-(L-isoglutamyl)-L-serine ! O-(L-isoglutamyl)-L-serine

2.954. MOD:00954 crosslinked residues with loss of water

Table 956. Term [MOD:00954]
id	MOD:00954
name	crosslinked residues with loss of water
def	"A protein modification that crosslinks two residues with a covalent bond and the loss of water." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.955. MOD:00955 alaninohistidine (serine crosslinked to tele or pros nitrogen of histidine)

Table 957. Term [MOD:00955]
id	MOD:00955
name	alaninohistidine (serine crosslinked to tele or pros nitrogen of histidine)
def	"A protein modification that effectively crosslinks an L-serine residue and an L-histidine residue to release water and form tele- or pros-(2-amino-2-carboxyethyl)histidine." [DeltaMass:0]
comment	Cross-link 2; From DeltaMass with no citation or formula: Average Mass: -18. The DeltaMass description "Serine crosslinked to theta or pi carbon of Histidine" is incorrect. The histidine ring nitrogens (not carbons) are designated tele or N-tau (not theta), and pros or N-pi [JSG].
synonym	"beta-alaninohistidine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 9 H 10 N 4 O 2"
xref	MassAvg: "206.20"
xref	MassMono: "206.080376"
xref	Origin: "H, S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.956. MOD:00956 misincorporation of norleucine for methionine

Table 958. Term [MOD:00956]
id	MOD:00956
name	misincorporation of norleucine for methionine
def	"modification from DeltaMass" [DeltaMass:10]
comment	From DeltaMass: Average Mass: -18 Average Mass Change:-18 Notes: It has the same mass as leucine or isoleucine and can be charged on the methionyl t-RNA. This often happens in minimal media-prepared fermentations that are not supplemented with enough free methionine. It gives a mass change of -18 and can often be confused with dehydration.
xref	DiffAvg: "-18.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S -1"
xref	DiffMono: "-17.956421"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "M"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01026 norleucine residue (Nle) ! norleucine residue (Nle)

2.957. MOD:00957 modified residue with neutral loss of carbon dioxide

Table 959. Term [MOD:00957]
id	MOD:00957
name	modified residue with neutral loss of carbon dioxide
def	"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue with a secondary loss of a neutral carbon dioxide molecular fragment." [PubMed:18688235]
synonym	"dCO2ModRes" EXACT PSI-MOD-label []
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss

2.958. MOD:00958 crosslink between Arg and His sidechains

Table 960. Term [MOD:00958]
id	MOD:00958
name	crosslink between Arg and His sidechains
def	"modification from DeltaMass" [DeltaMass:0]
comment	Cross-link 2; From DeltaMass: Average Mass: -5
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "H, R"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.959. MOD:00959 3,3',5,5'-TerTyr (Crosslink)

Table 961. Term [MOD:00959]
id	MOD:00959
name	3,3',5,5'-TerTyr (Crosslink)
def	"modification from DeltaMass" [DeltaMass:0]
comment	Cross-link 4; From DeltaMass: Average Mass: -4
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Y, Y, Y, Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues

2.960. MOD:00960 decarboxylated residue

Table 962. Term [MOD:00960]
id	MOD:00960
name	decarboxylated residue
def	"A protein modification that effectively replaces a carboxylic acid group with a hydrogen atom." [PubMed:18688235]
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.961. MOD:00961 reduction of disulfide crosslink in cystine to two cysteines

Table 963. Term [MOD:00961]
id	MOD:00961
name	reduction of disulfide crosslink in cystine to two cysteines
def	"A protein modification that effectively reduces the disulfide bond of cystine to form two cysteine residues." [DeltaMass:333]
comment	Cross-link 2; this modification destroys the cross-link. From DeltaMass: Treatment of cystine (cys-cys) by reducing agents such as dithiothreitol (DTT) or triscarboxyethylphosphine (TCEP) results in cleavage of the disulphide bond and reduction of the sulphur atom of each molecule to create cysteine.
subset	PSI-MOD-slim
xref	DiffAvg: "2.02"
xref	DiffFormula: "C 0 H 2 N 0 O 0 S 0"
xref	DiffMono: "2.015650"
xref	Formula: "C 6 H 10 N 2 O 2 S 2"
xref	MassAvg: "206.28"
xref	MassMono: "206.018370"
xref	Origin: "MOD:00034"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01473 hydrogenated residue ! hydrogenated residue
relationship	derives_from MOD:00034 L-cystine (cross-link) ! L-cystine (cross-link)

2.962. MOD:00962 2',3'-dihydrotryptophan

Table 964. Term [MOD:00962]
id	MOD:00962
name	2',3'-dihydrotryptophan
def	"A protein modification that by reducing the indole ring system of tryptophan to indoline effectively converts an L-tryptophan residue to 2',3'-dihydrotryptophan." [DeltaMass:343, URL:http\://dx.doi.org/10.1016/S0040-4039(00)99113-5]
comment	From DeltaMass: References:1. Pearson,D.A., Blanchette,M., Baker,M.L. and Guindon,C.A. (1989) Trialkylsilanes as scavengers for the trifluoroacetic acid deblocking ofprotecting groups in peptide synthesis. Tetrahedron Lett., 30(21), 2739-2742 Notes: Reduction of indole double bond of Trp which occurs when triethylsilane (TES) is used as a scavenger and Trp is incorporated without protection of indole nitrogen [1]. This side reaction is likely to be accompanied by oxidation of indoline ring with formation of intensively colored peptide by-products. Triisopropylsilane (TIPS) does not give this side reaction. See structure at http://www.abrf.org/images/misc/dmass2.gif. [However, the pictured indoline structure is incorrect - JSG].
xref	DiffAvg: "2.02"
xref	DiffFormula: "C 0 H 2 N 0 O 0 S 0"
xref	DiffMono: "2.015650"
xref	Formula: "C 11 H 12 N 2 O 1"
xref	MassAvg: "188.23"
xref	MassMono: "188.094963"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:01473 hydrogenated residue ! hydrogenated residue

2.963. MOD:00963 Oxidation of Trp to kynurenine

Table 965. Term [MOD:00963]
id	MOD:00963
name	Oxidation of Trp to kynurenine
def	"Modification from DeltaMass. OBSOLETE because redundant and identical to MOD:00462. Remap to MOD:00462." [DeltaMass:357]
comment	From DeltaMass: Average Mass: 4 Monoisotopic Mass Change:3.995 Average Mass Change:3.989 References:Ruoppolo M, Amoresano A, Pucci P, Pascarella S, Polticelli F, Trovato M,Menegatti E, Ascenzi P.Characterization of five new low-molecular-mass trypsin inhibitors fromwhite mustard (Sinapis alba L.) seed.Eur J Biochem. 2000 267:6486-92. Notes: See structure at http://www.abrf.org/images/misc/dmass32.jpg.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.964. MOD:00964 lysine epsilon amino to imine + 12 amu

Table 966. Term [MOD:00964]
id	MOD:00964
name	lysine epsilon amino to imine + 12 amu
def	"modification from DeltaMass" [DeltaMass:34]
comment	From DeltaMass: Average Mass: 12 Average Mass Change: 12 References: Mathews, W. Rodney; Runge, Thomas A.; Haroldsen, Peter E.; Gaskell, Simon J. (1989) Characterization of impurities in a synthetic renin substrate peptide by fast-atom bombardment mass spectrometry and hybrid tandem mass spectrometry. Rapid Commun. Mass Spectrom. 3(9), 314-19 Notes: Fast-atom bombardment mass spectrometry of a synthetic renin substrate decapeptide (Pro-His-Pro-Phe-His-Leu-Val-Ile-His-D-Lys) indicated the presence of several side products, including a component 12 Da higher in mass. Low-energy collisionally activated decompn analyses were performed using a hybrid tandem instrument and demonstrated that the heavier side product had two components, in which the structural modification was either at the N- or the C-terminus. Addnl. analyses of the N-acetyl deriv. indicated that for each component the structural modification blocked a site of N-acetylation. It is suggested that the formation of these side products is attributable to the generation of formaldehyde, during removal of the histidine protecting group (benzyloxymethyl), which reacts with the N-terminus of the peptide to give an imidazolidinone structure or with the D- lysine.epsilon.-amine group to yield an imine . While the precise genesis of the side-products remains speculative, it is clear that the combined strategy of derivatization and tandem mass spectrometry has allowed structural conclusions concerning individual components of an isobaric mixt.
synonym	"N6-(methylidene)-lysine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "12.01"
xref	DiffFormula: "C 1 H 0 N 0 O 0"
xref	DiffMono: "12.000000"
xref	Formula: "C 7 H 12 N 2 O 1"
xref	MassAvg: "140.19"
xref	MassMono: "140.094963"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.965. MOD:00965 4-thiazolidinecarboxylic acid

Table 967. Term [MOD:00965]
id	MOD:00965
name	4-thiazolidinecarboxylic acid
def	"A protein modification that effectively converts an N-terminal L-cysteine residue by a formadehyde adduct to 4-thiazolidinecarboxylic acid." [DeltaMass:342]
comment	From DeltaMass: References: Mitchell, M.A., Runge, T.A., Mathews, W.R., Ichhpurani, A.K., Harn, N.K., Dobrowolski, P.J. and Eckenrrrode, F.M. Problems associated with use of the benzylozymethyl protecting group for histidines. Formaldehyde adducts formed during cleavage by hydrogen fluoride. Int. J. Pept. Protein Res. 1990, 36(4), 350-355. Gesquiere, J.-C., Diesis, E. and Tartar, A. Conversion of N-terminal cysteine to thiazolidine carboxylic acid during hydrogen fluoride deprotection of peptides containing pi-N-Bom protected histidine. J. Chem. Soc. Chem. Commun. 1990, (20), 1402-1403. Kumagaye, K.Y., Inui, T., Nakajima, K., Kimura,T. and Sakakibara, S. Suppression of a side reaction associated with Nim-benzyloxymethyl group during synthesis of peptides containing cysteinyl residue at the N-terminus. Pept. Res. 1991, 4(2), 84-87. Colombo, R., Colombo, F. and Jones, J.H. Acid-labile histidine side-chain protection. The N(pi)-t-butoxymethyl group. J. Chem. Soc. Chem. Commun. 1984, (5), 292-293. Notes: Conversion of N-term Cys to thiazolidine during HF deprotection of His(Bom)-containing peptides [1-3]. See structure at http://www.abrf.org/images/misc/dmass12b.gif; modification in red. This modification cannot be excluded during final deprotection/cleavage in Fmoc-chemistry in cases when His(Bum) was employed [4]. For formation of free imino acid see PubMed:1527501.
synonym	"thioproline" EXACT DeltaMass-label []
xref	DiffAvg: "12.01"
xref	DiffFormula: "C 1 H 0 N 0 O 0 S 0"
xref	DiffMono: "12.000000"
xref	Formula: "C 4 H 6 N 1 O 1 S 1"
xref	MassAvg: "116.16"
xref	MassMono: "116.017010"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.966. MOD:00966 1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid

Table 968. Term [MOD:00966]
id	MOD:00966
name	1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid
def	"A protein modification that effectively converts an N-terminal L-tryptophan residue by a formadehyde adduct to 1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid." [DeltaMass:339]
comment	From DeltaMass: Average Mass: 12 Average Mass Change: 12 References: Lippke, K. P., W. G. Schunack, W. Wenning, W. E. Mueller. 1983..beta.-Carbolines as benzodiazepine receptor ligands. 1. Synthesis andbenzodiazepine receptor interaction of esters of.beta.-carboline-3-carboxylic acid. J. Med. Chem.26: 499-503 Cain, M., R. W. Weber, F. Guzman, J. M. Cook, S. A. Barker, K. C.Rice, J. N. Crawley, S. M. Paul, P. Skolnick. 1982. .beta.-Carbolines:synthesis and neurochemical and pharmacological actions on brainbenzodiazepine receptors.J. Med. Chem. 25: 1081-91 Notes: +12 Da modification corresponds to formaldehyde adduct of Trp having beta-carboline structure (methylene bridge links carbon-2 of indole ring and alfa-N. See structure at http://www.abrf.org/images/misc/dmass12a.gif; modification in red.
xref	DiffAvg: "12.01"
xref	DiffFormula: "C 1 H 0 N 0 O 0 S 0"
xref	DiffMono: "12.000000"
xref	Formula: "C 12 H 10 N 2 O 1"
xref	MassAvg: "198.22"
xref	MassMono: "198.079313"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.967. MOD:00967 syndesine

Table 969. Term [MOD:00967]
id	MOD:00967
name	syndesine
def	"A protein modification that effectively cross-links two L-lysine residues to form syndesine, hydroxylysinohydroxynorleucine." [DeltaMass:35, PubMed:75151974]
comment	Cross-link 2; From DeltaMass: Average Mass: 13 Average Mass Change: 13 (incorrect) [JSG].
synonym	"hydroxylysinohydroxynorleucine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "16.96"
xref	DiffFormula: "C 0 H -3 N -2 O 3"
xref	DiffMono: "16.955121"
xref	Formula: "C 12 H 21 N 2 O 5"
xref	MassAvg: "273.31"
xref	MassMono: "273.145047"
xref	Origin: "K, K"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.968. MOD:00968 CM-Cys vs PAM-Cys

Table 970. Term [MOD:00968]
id	MOD:00968
name	CM-Cys vs PAM-Cys
def	"modification from DeltaMass" [DeltaMass:347]
comment	From DeltaMass: Average Mass: 13 Formula:C2H2O2 vs C3H5ON Monoisotopic Mass Change:13.03 Average Mass Change:13.05 Notes:Residual acrylamide in SDS gels can partly label cysteine residues in proteins (propionamido-Cys, PAM-Cys, DeltaMass +71Da; see entry). Subsequent alkylation of protein bands with iodoacetic acid e.g. in preparation for proteomic analysis, will convert remaining free cysteines into carboxymethyl-Cys (CM-Cys, DeltaMass +58Da; see entry). Peptide mass fingerprinting may therefore potentially reveal the same cysteine-containing peptide in two forms, differing in mass by 13Da. The relative ratios of the peaks will depend on the initial degree of labelling with acrylamide. Use of high quality, deionised acrylamide in the SDS gel will minimise modification of cysteine through this route. Where it remains a problem, deliberate alkylation using acrylamide instead of iodoacetamide will ensure chemical homogeneity of the final product.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.969. MOD:00969 CAM-Cys vs PAM-Cys

Table 971. Term [MOD:00969]
id	MOD:00969
name	CAM-Cys vs PAM-Cys
def	"modification from DeltaMass" [DeltaMass:346]
comment	From DeltaMass: Average Mass: 14 Formula:CH2 Monoisotopic Mass Change:14.016 Average Mass Change:14.027 Notes: Residual acrylamide in SDS gels can partly label cysteine residues in proteins (propionamido-Cys, PAM-Cys, DeltaMass +71Da; see entry). Subsequent alkylation of protein bands with iodoacetamide e.g. in preparation for proteomic analysis, will convert remaining free cysteines into carboxamidomethyl-Cys (CAM-Cys, DeltaMass +57Da; see entry). Peptide mass fingerprinting may therefore potentially reveal the same cysteine-containing peptide in two forms, differing in mass by 14Da. The relative ratios of the peaks will depend on the initial degree of labelling with acrylamide. Use of high quality, deionised acrylamide in the SDS gel will minimise modification of cysteine through this route. Where it remains a problem, deliberate alkylation using acrylamide instead of iodoacetamide will ensure chemical homogeneity of the final product.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.970. MOD:00970 delta-hydroxy-allysine (Lys)

Table 972. Term [MOD:00970]
id	MOD:00970
name	delta-hydroxy-allysine (Lys)
def	"modification from DeltaMass" [DeltaMass:37]
comment	From DeltaMass: Average Mass: 15 Average Mass Change:15 Notes:In going from Lys to hydroxy-allysine, two separate reactions are involved:1. the oxidative deamination converting Lys to allysine (-CH2NH2 being converted to -CHO) with a net mass change of -1;2.conversion of allysine to delta-hydroxy-allysine (-CH2-CHO being converted to -CH(OH)-CHO) with a mass change of +16. The net change from Lys to hydroxyallysine thus is +15.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.971. MOD:00971 Oxohistidine (from histidine)

Table 973. Term [MOD:00971]
id	MOD:00971
name	Oxohistidine (from histidine)
def	"modification from DeltaMass" [DeltaMass:38]
comment	From DeltaMass: Average Mass: 16 Average Mass Change:16 References:Lewisch, S. A. and Levine, R. L. (1995) Anal. Biochem. 231, 440-446. Determination of 2-oxo-histidine by amino acid analysis Notes:Rod LevineNIHBldg 3, Room 106 MSC 0320Bethesda, MD 20892-0320email: rlevine@nih.govvoice: 1 (301) 496-2310fax: 1 (301) 496-0599
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "H"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.972. MOD:00972 monobrominated L-phenylalanine

Table 974. Term [MOD:00972]
id	MOD:00972
name	monobrominated L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to a monobrominated L-phenylalanine, such as L-2'-bromophenylalanine." [UniMod:340#F]
comment	From DeltaMass: Average Mass: 78 Average Mass Change:78 References:Yoshino,K et.al. Biochemistry Vol. 30 pg 6203-9 (1991) Identifidation of a novel amino acid, o-bromo-L-phenylananine, in egg-associated peptides that activate spermatozoa
synonym	"Br1Phe" EXACT PSI-MOD-label []
synonym	"bromination" RELATED UniMod-description []
synonym	"Bromo" RELATED PSI-MS-label []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 9 H 8 N 1 O 1"
xref	MassAvg: "226.07"
xref	MassMono: "224.978926"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01066 halogenated phenylalanine ! halogenated phenylalanine
is_a	MOD:01912 monobrominated residue ! monobrominated residue

2.973. MOD:00973 Oxidation of proline (to glutamic acid)

Table 975. Term [MOD:00973]
id	MOD:00973
name	Oxidation of proline (to glutamic acid)
def	"modification from DeltaMass" [DeltaMass:355]
comment	From DeltaMass: Average Mass: 32 Monoisotopic Mass Change:31.99 Average Mass Change:32 References:Amici A, Levine, RL, Tsai, L, and Stadtman, ER: Conversion of amino acid residues in proteins and amino acid homopolymers to carbonyl derivatives by metal-catalyzed oxidation reactions. Journal of Biological Chemistry 264: 3341-3346 1989.Rod Levine (unpublished)
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.974. MOD:00974 (35)Cl labeled 3'-chlorotyrosine

Table 976. Term [MOD:00974]
id	MOD:00974
name	(35)Cl labeled 3'-chlorotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 34
xref	DiffAvg: "33.96"
xref	DiffFormula: "(35)Cl 1 H -1"
xref	DiffMono: "33.961028"
xref	Formula: "C 9 (35)Cl 1 H 8 N 1 O 2"
xref	MassAvg: "197.02"
xref	MassMono: "197.024356"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01046 3'-chloro-L-tyrosine ! 3'-chloro-L-tyrosine

2.975. MOD:00975 (37)Cl labeled 3'-chlorotyrosine

Table 977. Term [MOD:00975]
id	MOD:00975
name	(37)Cl labeled 3'-chlorotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 36
xref	DiffAvg: "35.96"
xref	DiffFormula: "(37)Cl 1 H -1"
xref	DiffMono: "35.958078"
xref	Formula: "C 9 (37)Cl 1 H 8 N 1 O 2"
xref	MassAvg: "199.02"
xref	MassMono: "199.021406"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01046 3'-chloro-L-tyrosine ! 3'-chloro-L-tyrosine

2.976. MOD:00976 potassium salt

Table 978. Term [MOD:00976]
id	MOD:00976
name	potassium salt
def	"modification from DeltaMass - OBSOLETE because redundant and identical to MOD:01072. Remap to MOD:01072." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 38
xref	DiffAvg: "38.09"
xref	DiffFormula: "H -1 K 1"
xref	DiffMono: "37.955882"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.977. MOD:00977 disodium salt

Table 979. Term [MOD:00977]
id	MOD:00977
name	disodium salt
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 44
subset	PSI-MOD-slim
xref	DiffAvg: "43.96"
xref	DiffFormula: "H -2 Na 2"
xref	DiffMono: "43.963888"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00747 sodium containing modified residue ! sodium containing modified residue

2.978. MOD:00978 piperidine adduct to C-terminal Cys

Table 980. Term [MOD:00978]
id	MOD:00978
name	piperidine adduct to C-terminal Cys
def	"modification from DeltaMass" [DeltaMass:345]
comment	From DeltaMass: Average Mass: 51 Average Mass Change: 51 References:Lukszo, Patterson, Albericio, and Kates, Letters in Peptide Science 3, 157-166(1996) Notes:The side reaction can be very significant, and the level to which it occurs depends on how the C-terminal Cys is anchored and what the side-chain protecting group is. The mechanism involves piperidine-mediated beta-elimination of sulfur (with the protecting group on), followed by addition of piperidine across the C-terminaldehydroalanine. Since this last-mentioned step creates a chiral center, a mixture of diastereomers is formed which in special cases can be separatedby HPLC. Another problem with C-terminal Cys is racemization; some references in the review article by Andreu, Albericio, Sole, Munson, Ferrer, and Barany in Pennington-Dunn Peptide Synthesis and Purification Protocols, vol 35, 1994, pp. 91-169.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.979. MOD:00979 t-butyl ester (OtBu) and t-butyl (tBu)

Table 981. Term [MOD:00979]
id	MOD:00979
name	t-butyl ester (OtBu) and t-butyl (tBu)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 56
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.980. MOD:00980 Carboxamidomethyl (on Cysteine)

Table 982. Term [MOD:00980]
id	MOD:00980
name	Carboxamidomethyl (on Cysteine)
def	"modification from DeltaMass - OBSOLETE because redundant, the difference component of MOD:01060. Remap to MOD:01060." [DeltaMass:337]
comment	From DeltaMass: Average Mass: 57 Abbreviation:CamCys Formula:C2H3NO Monoisotopic Mass Change:57.021 Average Mass Change:57.051 Notes:Cysteine reacts with iodoacetamide to produce carboxamidomethyl cysteine. Alternative names are often used, such as amidocarboxymethylcysteine and carbamoylmethylcysteine
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.981. MOD:00981 sodium and potassium salt

Table 983. Term [MOD:00981]
id	MOD:00981
name	sodium and potassium salt
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 60
subset	PSI-MOD-slim
xref	DiffAvg: "60.07"
xref	DiffFormula: "H -2 K 1 Na 1"
xref	DiffMono: "59.937826"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00747 sodium containing modified residue ! sodium containing modified residue
is_a	MOD:00849 potassium containing modified residue ! potassium containing modified residue

2.982. MOD:00982 L-selenocysteine (Ser)

Table 984. Term [MOD:00982]
id	MOD:00982
name	L-selenocysteine (Ser)
def	"A protein modification that effectively converts an L-serine residue to L-selenocysteine (not known as a natural post-translational modification process)." [DeltaMass:0]
comment	[From DeltaMass: Average Mass: 64.] Although selenocysteine-charged tRNA(Sec) is biosynthesized from serine-charged tRNA(Sec), in peptide work selenocysteine is usually considered as either a natural residue or as a modified cysteine residue. This entry is for the artifactual formation of L-selenocysteine from serine. For encoded L-selenocysteine, use MOD:00031 [JSG].
synonym	"Sec(Ser)" EXACT PSI-MOD-label []
synonym	"Selenocysteine (from Serine)" EXACT DeltaMass-label []
xref	DiffAvg: "62.97"
xref	DiffFormula: "C 0 H 0 N 0 O -1 Se 1"
xref	DiffMono: "63.921607"
xref	Formula: "C 3 H 5 N 1 O 1 Se 1"
xref	MassAvg: "150.05"
xref	MassMono: "150.953635"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00031 L-selenocysteine residue ! L-selenocysteine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.983. MOD:00983 Asp transamidation with piperidine

Table 985. Term [MOD:00983]
id	MOD:00983
name	Asp transamidation with piperidine
def	"modification from DeltaMass" [DeltaMass:67]
comment	From DeltaMass: Average Mass: 67 Average Mass Change:67 References:http://www.abrf.org/archives/hmail/0008/0007.html Notes:1.) Get rid of the DBU. It can cause piperidine amides at Asp residues. The tbu ester side chain comes off during synthesis and the residue is trans-amidated with piperidine (+67Da by MS). If you haven’t yet seen this, you will. Even "normal" 20% pip/DMF (NMP) will cause this, but less frequently. Literature exists for this; I don’t remember the exact reference. David H. Singleton Scientist Pfizer Central Research PO Box 8118-101 Eastern Point Road Groton, CT 06340 (860)441-4404.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.984. MOD:00984 (35)Cl labeled 3',5'-dichlorotyrosine

Table 986. Term [MOD:00984]
id	MOD:00984
name	(35)Cl labeled 3',5'-dichlorotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 68
xref	DiffAvg: "67.92"
xref	DiffFormula: "(35)Cl 2 H -2"
xref	DiffMono: "67.922055"
xref	Formula: "C 9 (35)Cl 2 H 7 N 1 O 2"
xref	MassAvg: "230.99"
xref	MassMono: "230.985384"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01045 3',5'-dichloro-L-tyrosine ! 3',5'-dichloro-L-tyrosine

2.985. MOD:00985 halogenated tyrosine

Table 987. Term [MOD:00985]
id	MOD:00985
name	halogenated tyrosine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-tyrosine residue with a halogen atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HalTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.986. MOD:00986 (35)Cl and (37)Cl labeled 3',5'-dichlorotyrosine

Table 988. Term [MOD:00986]
id	MOD:00986
name	(35)Cl and (37)Cl labeled 3',5'-dichlorotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 70.
xref	DiffAvg: "69.92"
xref	DiffFormula: "(35)Cl 1 (37)Cl 1 H -2"
xref	DiffMono: "69.919105"
xref	Formula: "C 9 (35)Cl 1 (37)Cl 1 H 7 N 1 O 2"
xref	MassAvg: "232.98"
xref	MassMono: "232.982434"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01045 3',5'-dichloro-L-tyrosine ! 3',5'-dichloro-L-tyrosine

2.987. MOD:00987 chlorinated tyrosine

Table 989. Term [MOD:00987]
id	MOD:00987
name	chlorinated tyrosine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-tyrosine residue with a chlorine atom." [PubMed:18688235]
synonym	"ClTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00753 chlorinated residue ! chlorinated residue
is_a	MOD:00985 halogenated tyrosine ! halogenated tyrosine

2.988. MOD:00988 brominated tyrosine

Table 990. Term [MOD:00988]
id	MOD:00988
name	brominated tyrosine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-tyrosine residue with a bromine atom." [PubMed:18688235]
synonym	"BrTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00754 brominated residue ! brominated residue
is_a	MOD:00985 halogenated tyrosine ! halogenated tyrosine

2.989. MOD:00989 acetamidomethyl (Acm)

Table 991. Term [MOD:00989]
id	MOD:00989
name	acetamidomethyl (Acm)
def	"OBSOLETE because redundant, the difference component of MOD:01079. Remap to MOD:01079." [DeltaMass:0]
comment	From DeltaMass with no citation or formula.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.990. MOD:00990 (37)Cl labeled 3',5'-dichlorotyrosine

Table 992. Term [MOD:00990]
id	MOD:00990
name	(37)Cl labeled 3',5'-dichlorotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 72
xref	DiffAvg: "71.92"
xref	DiffFormula: "(37)Cl 2 H -2"
xref	DiffMono: "71.916155"
xref	Formula: "C 9 (37)Cl 2 H 7 N 1 O 2"
xref	MassAvg: "234.98"
xref	MassMono: "234.979484"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01045 3',5'-dichloro-L-tyrosine ! 3',5'-dichloro-L-tyrosine

2.991. MOD:00991 S-(sn-1-glyceryl)-L-cysteine

Table 993. Term [MOD:00991]
id	MOD:00991
name	S-(sn-1-glyceryl)-L-cysteine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 74 with no citation.
xref	DiffAvg: "74.08"
xref	DiffFormula: "C 3 H 6 O 2"
xref	DiffMono: "74.036779"
xref	Formula: "C 6 H 11 N 1 O 3 S 1"
xref	MassAvg: "177.22"
xref	MassMono: "177.045964"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.992. MOD:00992 glutamate 5-glycerol ester

Table 994. Term [MOD:00992]
id	MOD:00992
name	glutamate 5-glycerol ester
def	"modification from DeltaMass" [DeltaMass:78, PubMed:18767873]
comment	From DeltaMass: Average Mass: 74 Average Mass Change: 74 References: Anal. Biochem. 1993 Vol 208 No. 2 382-386, PubMed:8452236. [DeltaMass] This article only suggests this as a possible modification and does no characterization. Isolation and stuctural evidence for artifactual modification are found in PubMed:18767873 [JSG].
xref	DiffAvg: "74.08"
xref	DiffFormula: "C 3 H 6 O 2"
xref	DiffMono: "74.036779"
xref	Formula: "C 8 H 13 N 1 O 5"
xref	MassAvg: "203.19"
xref	MassMono: "203.079373"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.993. MOD:00993 phenyl ester

Table 995. Term [MOD:00993]
id	MOD:00993
name	phenyl ester
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 76, on acidic amino acids
synonym	"OPh" EXACT DeltaMass-label []
xref	DiffAvg: "76.10"
xref	DiffFormula: "C 6 H 4"
xref	DiffMono: "76.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.994. MOD:00994 (79)Br labeled 3'-bromotyrosine

Table 996. Term [MOD:00994]
id	MOD:00994
name	(79)Br labeled 3'-bromotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 78
xref	DiffAvg: "77.91"
xref	DiffFormula: "(79)Br 1 H -1"
xref	DiffMono: "77.910512"
xref	Formula: "(79)Br 1 C 9 H 8 N 1 O 2"
xref	MassAvg: "240.97"
xref	MassMono: "240.973841"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01025 3'-bromo-L-tyrosine ! 3'-bromo-L-tyrosine

2.995. MOD:00995 (81)Br labeled 2'-bromophenylalanine

Table 997. Term [MOD:00995]
id	MOD:00995
name	(81)Br labeled 2'-bromophenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to (81)Br-L-2'-bromophenylalanine." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 80
xref	DiffAvg: "79.91"
xref	DiffFormula: "(81)Br 1 H -1"
xref	DiffMono: "79.908466"
xref	Formula: "(81)Br 1 C 9 H 8 N 1 O 1"
xref	MassAvg: "226.98"
xref	MassMono: "226.976879"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00183 L-2'-bromophenylalanine ! L-2'-bromophenylalanine

2.996. MOD:00996 (81)Br labeled 3'-bromotyrosine

Table 998. Term [MOD:00996]
id	MOD:00996
name	(81)Br labeled 3'-bromotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 80
xref	DiffAvg: "79.91"
xref	DiffFormula: "(81)Br 1 H -1"
xref	DiffMono: "79.908466"
xref	Formula: "(81)Br 1 C 9 H 8 N 1 O 2"
xref	MassAvg: "242.97"
xref	MassMono: "242.971794"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01025 3'-bromo-L-tyrosine ! 3'-bromo-L-tyrosine

2.997. MOD:00997 cyclohexyl ester

Table 999. Term [MOD:00997]
id	MOD:00997
name	cyclohexyl ester
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 82
synonym	"OcHex" EXACT DeltaMass-label []
xref	DiffAvg: "82.15"
xref	DiffFormula: "C 6 H 10"
xref	DiffMono: "82.078250"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.998. MOD:00998 iodinated tyrosine

Table 1000. Term [MOD:00998]
id	MOD:00998
name	iodinated tyrosine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-tyrosine residue with an iodine atom." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"ITyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00755 iodinated residue ! iodinated residue
is_a	MOD:00985 halogenated tyrosine ! halogenated tyrosine

2.999. MOD:00999 homoseryl lactone

Table 1001. Term [MOD:00999]
id	MOD:00999
name	homoseryl lactone
def	"OBSOLETE because redundant and identical to MOD:00404. Remap to MOD:00404." [DeltaMass:90]
comment	From DeltaMass: Average Mass: 83 Formula:C4H5O1N1 Monoisotopic Mass Change:83.037 Average Mass Change:83.09
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1000. MOD:01000 monobrominated tyrosine

Table 1002. Term [MOD:01000]
id	MOD:01000
name	monobrominated tyrosine
def	"A protein modification that effectively substitutes one hydrogen atom of an L-tyrosine residue with one bromine atom." [PubMed:18688235]
synonym	"Br1Tyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00988 brominated tyrosine ! brominated tyrosine

2.1001. MOD:01001 2-aminoisobutyric acid residue (Aib)

Table 1003. Term [MOD:01001]
id	MOD:01001
name	2-aminoisobutyric acid residue (Aib)
def	"A protein modification that inserts or replaces a residue with a 2-aminoisobutyric acid." [DeltaMass:0]
comment	Modification from DeltaMass: Average Mass: 85.
synonym	"2-amino-2-methylpropanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-2-methylpropionic acid" EXACT PSI-MOD-alternate []
synonym	"2-methylalanine" EXACT PSI-MOD-alternate []
synonym	"Aib" EXACT PSI-MOD-alternate []
synonym	"alpha,alpha-dimethylglycine" EXACT PSI-MOD-alternate []
synonym	"alpha-aminoisobutyric acid" EXACT PSI-MOD-alternate []
synonym	"alpha-methylalanine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 4 H 7 N 1 O 1"
xref	MassAvg: "85.11"
xref	MassMono: "85.052764"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00850 unnatural residue ! unnatural residue

2.1002. MOD:01002 gamma-aminobutyryl

Table 1004. Term [MOD:01002]
id	MOD:01002
name	gamma-aminobutyryl
def	"modification from DeltaMass" [DeltaMass:92]
comment	From DeltaMass: Average Mass: 85 Formula: C 4 H 7 O 1 N 1 Monoisotopic Mass Change: 85.053 Average Mass Change: 85.106
xref	DiffAvg: "85.11"
xref	DiffFormula: "C 4 H 7 N 1 O 1"
xref	DiffMono: "85.052764"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1003. MOD:01003 t-butyloxymethyl (Bum)

Table 1005. Term [MOD:01003]
id	MOD:01003
name	t-butyloxymethyl (Bum)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 86
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1004. MOD:01004 diaminopropionyl

Table 1006. Term [MOD:01004]
id	MOD:01004
name	diaminopropionyl
def	"modification from DeltaMass" [DeltaMass:95]
comment	From DeltaMass: Average Mass: 86 Formula: C 3 H 6 O 2 N 1 Monoisotopic Mass Change: 86.048 Average Mass Change: 86.094
xref	DiffAvg: "86.09"
xref	DiffFormula: "C 3 H 6 N 2 O 1"
xref	DiffMono: "86.048013"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1005. MOD:01005 t-butylsulfenyl

Table 1007. Term [MOD:01005]
id	MOD:01005
name	t-butylsulfenyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 88
synonym	"StBu" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1006. MOD:01006 dibrominated tyrosine

Table 1008. Term [MOD:01006]
id	MOD:01006
name	dibrominated tyrosine
def	"A protein modification that effectively substitutes two hydrogen atoms of an L-tyrosine residue with two bromine atoms." [UniMod:534]
synonym	"Br2Tyr" EXACT PSI-MOD-label []
synonym	"Dibromo" RELATED PSI-MS-label []
synonym	"Dibromo" RELATED UniMod-description []
xref	DiffAvg: "157.79"
xref	DiffFormula: "Br 2 C 0 H -2 N 0 O 0"
xref	DiffMono: "155.821024"
xref	Formula: "Br 2 C 9 H 7 N 1 O 2"
xref	MassAvg: "320.97"
xref	MassMono: "318.884353"
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00988 brominated tyrosine ! brominated tyrosine

2.1007. MOD:01007 anisyl modified residue

Table 1009. Term [MOD:01007]
id	MOD:01007
name	anisyl modified residue
def	"A protein modification that effectively substitutes an anisyl (methoxyphenyl) group for a hydroxyl group, typically at the 4 or para position." [DeltaMass:0]
comment	From DeltaMass with no citation or formula: Average Mass: 90.
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1008. MOD:01008 benzyl (Bzl) and benzyl ester (OBzl) modified residue

Table 1010. Term [MOD:01008]
id	MOD:01008
name	benzyl (Bzl) and benzyl ester (OBzl) modified residue
def	"A protein modification that effectively substitutes a benzyl (phenylmethyl) group for a hydrogen atom." [DeltaMass:0]
comment	From DeltaMass with no citation or formula: Average Mass: 90
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1009. MOD:01009 dehydrogenated proline

Table 1011. Term [MOD:01009]
id	MOD:01009
name	dehydrogenated proline
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass with no citation.
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 5 H 5 N 1 O 1"
xref	MassAvg: "95.10"
xref	MassMono: "95.037114"
xref	Origin: "P"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1010. MOD:01010 trifluoroacetylated residue

Table 1012. Term [MOD:01010]
id	MOD:01010
name	trifluoroacetylated residue
def	"A protein modification that effectively substitutes a trifluoroacetyl group for a hydrogen atom." [DeltaMass:0]
synonym	"TFA" EXACT DeltaMass-label []
xref	DiffAvg: "96.01"
xref	DiffFormula: "C 2 F 3 H -1 O 1"
xref	DiffMono: "95.982299"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1011. MOD:01011 N-hydroxysuccinimide (ONSu, OSu)

Table 1013. Term [MOD:01011]
id	MOD:01011
name	N-hydroxysuccinimide (ONSu, OSu)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 97
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1012. MOD:01012 oxidation of disulfide crosslink in cystine to two cysteic acids

Table 1014. Term [MOD:01012]
id	MOD:01012
name	oxidation of disulfide crosslink in cystine to two cysteic acids
def	"A protein modification that effectively oxidizes the disulfide bond of a cystine crosslink to form two cysteic acid residues." [DeltaMass:335]
comment	Cross-link 2. This modification destroys a cross-link. From DeltaMass: Average Mass: 98 Abbreviation: Cya Average Mass Change: 98 Notes: Treatment of cystine by strongly oxidising reagents such as performic acid results in the breakage of the disulphide bond and complete oxidation of the sulphur atoms on each molecule. Such treatment is often carried out prior to amino acid analysis as the resulting cysteic acid is then resistant to acid degradation during the hydrolysis procedure.
xref	DiffAvg: "98.01"
xref	DiffFormula: "C 0 H 2 N 0 O 6 S 0"
xref	DiffMono: "97.985138"
xref	Formula: "C 6 H 10 N 2 O 8 S 2"
xref	MassAvg: "302.27"
xref	MassMono: "301.987857"
xref	Origin: "MOD:00034"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00460 L-cysteic acid (L-cysteine sulfonic acid) ! L-cysteic acid (L-cysteine sulfonic acid)
relationship	derives_from MOD:00034 L-cystine (cross-link) ! L-cystine (cross-link)

2.1013. MOD:01013 tetramethylguanidinium termination by-product on amine

Table 1015. Term [MOD:01013]
id	MOD:01013
name	tetramethylguanidinium termination by-product on amine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 98
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1014. MOD:01014 phosphate/sulphate adduct of proteins

Table 1016. Term [MOD:01014]
id	MOD:01014
name	phosphate/sulphate adduct of proteins
def	"modification from DeltaMass" [DeltaMass:358]
comment	From DeltaMass: Average Mass: 98 Formula:H3PO4 or H2SO4 Monoisotopic Mass Change:97.97 Average Mass Change:98 Notes:Proteins may pick up non-covalent salt adducts during purification. Phosphate and sulphate salts are commonly used and may be observed as +98 amu adducts (or multiples thereof) forming ion pairs with basic residues. Monoisotopic masses H2SO4 97.967, H3PO4 97.977
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1015. MOD:01015 isovaline residue (Iva)

Table 1017. Term [MOD:01015]
id	MOD:01015
name	isovaline residue (Iva)
def	"A protein modification that inserts or replaces a residue with an isovaline." [DeltaMass:110]
synonym	"2-amino-2-methylbutanoic acid" EXACT PSI-MOD-alternate []
synonym	"Isovalyl (-I-,-Iva-)" EXACT DeltaMass-label []
synonym	"Iva" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 9 N 1 O 1"
xref	MassAvg: "99.13"
xref	MassMono: "99.068414"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00850 unnatural residue ! unnatural residue

2.1016. MOD:01016 t-butyloxycarbonyl

Table 1018. Term [MOD:01016]
id	MOD:01016
name	t-butyloxycarbonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 100
synonym	"tBoc" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1017. MOD:01017 homoseryl (-Hse-)

Table 1019. Term [MOD:01017]
id	MOD:01017
name	homoseryl (-Hse-)
def	"OBSOLETE because redundant and identical to MOD:00403. Remap to MOD:00403." [DeltaMass:113]
comment	From DeltaMass: Average Mass: 101 Abbreviation:-Hse- Formula:C4H7O2N Monoisotopic Mass Change:101.048 Average Mass Change:101.105
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1018. MOD:01018 4-methylbenzyl

Table 1020. Term [MOD:01018]
id	MOD:01018
name	4-methylbenzyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 104
synonym	"Meb" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1019. MOD:01019 hydroxymethylphenyl linker

Table 1021. Term [MOD:01019]
id	MOD:01019
name	hydroxymethylphenyl linker
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 106
synonym	"HMP" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1020. MOD:01020 thioanisyl

Table 1022. Term [MOD:01020]
id	MOD:01020
name	thioanisyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 106
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1021. MOD:01021 thiocresyl

Table 1023. Term [MOD:01021]
id	MOD:01021
name	thiocresyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 106
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1022. MOD:01022 2-piperidinecarboxylic acid

Table 1024. Term [MOD:01022]
id	MOD:01022
name	2-piperidinecarboxylic acid
def	"A protein modification that effectively converts an L-lysine residue to 2-piperidinecarboxylic acid." [DeltaMass:0]
synonym	"Pip" EXACT DeltaMass-label []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 6 H 9 N 1 O 1"
xref	MassAvg: "111.14"
xref	MassMono: "111.068414"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01160 deaminated residue ! deaminated residue

2.1023. MOD:01023 3',5'-dibromo-L-tyrosine

Table 1025. Term [MOD:01023]
id	MOD:01023
name	3',5'-dibromo-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3',5'-dibromo-L-tyrosine." [DeltaMass:156]
synonym	"3',5'-Br2Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "157.79"
xref	DiffFormula: "Br 2 C 0 H -2 N 0 O 0"
xref	DiffMono: "155.821024"
xref	Formula: "Br 2 C 9 H 7 N 1 O 2"
xref	MassAvg: "320.97"
xref	MassMono: "318.884353"
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01006 dibrominated tyrosine ! dibrominated tyrosine

2.1024. MOD:01024 monohydroxylated proline

Table 1026. Term [MOD:01024]
id	MOD:01024
name	monohydroxylated proline
def	"A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline." [DeltaMass:0, OMSSA:62, UniMod:35#P]
comment	From DeltaMass: Average Mass: 131. This is the mass of the free amino acid [JSG].
subset	PSI-MOD-slim
synonym	"Hy1Pro" EXACT PSI-MOD-label []
synonym	"hydroxylationp" EXACT OMSSA-label []
synonym	"Hydroxyproline" EXACT DeltaMass-label []
synonym	"Hyp" EXACT DeltaMass-label []
synonym	"Oxidation" RELATED PSI-MS-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00594 residues isobaric at 113.047678 Da ! residues isobaric at 113.047678 Da
is_a	MOD:00678 hydroxylated proline ! hydroxylated proline

2.1025. MOD:01025 3'-bromo-L-tyrosine

Table 1027. Term [MOD:01025]
id	MOD:01025
name	3'-bromo-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3'-bromo-L-tyrosine." [PubMed:18688235]
synonym	"3'-BrTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 H -1"
xref	DiffMono: "77.910512"
xref	Formula: "Br 1 C 9 H 8 N 1 O 2"
xref	MassAvg: "242.07"
xref	MassMono: "240.973841"
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01000 monobrominated tyrosine ! monobrominated tyrosine

2.1026. MOD:01026 norleucine residue (Nle)

Table 1028. Term [MOD:01026]
id	MOD:01026
name	norleucine residue (Nle)
def	"A protein modification that inserts or replaces a residue with a norleucine." [DeltaMass:126]
synonym	"Nle" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00850 unnatural residue ! unnatural residue

2.1027. MOD:01027 t-amyloxycarbonyl

Table 1029. Term [MOD:01027]
id	MOD:01027
name	t-amyloxycarbonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 114
synonym	"Aoc" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1028. MOD:01028 monochlorinated L-tyrosine

Table 1030. Term [MOD:01028]
id	MOD:01028
name	monochlorinated L-tyrosine
def	"A protein modification that effectively substitutes one hydrogen atom of an L-tyrosine residue with one chlorine atom." [PubMed:18688235]
synonym	"Cl1Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 9 Cl 1 H 8 N 1 O 2"
xref	MassAvg: "197.62"
xref	MassMono: "197.024356"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00987 chlorinated tyrosine ! chlorinated tyrosine
is_a	MOD:01911 monochlorinated residue ! monochlorinated residue

2.1029. MOD:01029 succinylated residue

Table 1031. Term [MOD:01029]
id	MOD:01029
name	succinylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a succinyl group linked through a carbonyl carbon." [DeltaMass:0, UniMod:64]
comment	From DeltaMass with no citation or formula, Average Mass: 117 [JSG].
subset	PSI-MOD-slim
synonym	"Succinic anhydride labeling reagent light form (N-term & K)" RELATED UniMod-description []
xref	DiffAvg: "100.07"
xref	DiffFormula: "C 4 H 4 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1030. MOD:01030 hydroxybenzotriazole ester

Table 1032. Term [MOD:01030]
id	MOD:01030
name	hydroxybenzotriazole ester
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 117
synonym	"HOBt" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1031. MOD:01031 dimethylbenzyl

Table 1033. Term [MOD:01031]
id	MOD:01031
name	dimethylbenzyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 118
synonym	"diMeBzl" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1032. MOD:01032 benzyloxymethyl modified residue

Table 1034. Term [MOD:01032]
id	MOD:01032
name	benzyloxymethyl modified residue
def	"A protein modification that effectively substitutes a benzyloxymethyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Bom" EXACT DeltaMass-label []
xref	DiffAvg: "120.15"
xref	DiffFormula: "C 8 H 8 O 1"
xref	DiffMono: "120.057515"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1033. MOD:01033 p-methoxybenzyl modified residue

Table 1035. Term [MOD:01033]
id	MOD:01033
name	p-methoxybenzyl modified residue
def	"A protein modification that effectively substitutes a p-methoxybenzyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Mbzl" EXACT DeltaMass-label []
synonym	"Mob" EXACT DeltaMass-label []
xref	DiffAvg: "120.15"
xref	DiffFormula: "C 8 H 8 O 1"
xref	DiffMono: "120.057515"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1034. MOD:01034 4-nitrophenyl modified residue

Table 1036. Term [MOD:01034]
id	MOD:01034
name	4-nitrophenyl modified residue
def	"A protein modification that effectively substitutes a 4-nitrophenyl group for a hydrogen atom." [DeltaMass:0]
synonym	"ONp" EXACT DeltaMass-label []
synonym	"p-nitrophenyl" EXACT DeltaMass-label []
xref	DiffAvg: "121.10"
xref	DiffFormula: "C 6 H 3 N 1 O 2"
xref	DiffMono: "121.016378"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1035. MOD:01035 chlorobenzyl

Table 1037. Term [MOD:01035]
id	MOD:01035
name	chlorobenzyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 125
synonym	"ClBzl" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1036. MOD:01036 O-methyl aspartyl

Table 1038. Term [MOD:01036]
id	MOD:01036
name	O-methyl aspartyl
def	"OBSOLETE because redundant and identical to MOD:01181. Remap to MOD:01181." [PubMed:18688235]
comment	From DeltaMass:148 (name misspelled "aspartamyl", and formula incorrect, N and O reversed) Average Mass: 129 Formula: C5H7O1N3 Monoisotopic Mass Change: 129.042 Average Mass Change: 129.116
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "D"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1037. MOD:01037 dichlorinated tyrosine

Table 1039. Term [MOD:01037]
id	MOD:01037
name	dichlorinated tyrosine
def	"A protein modification that effectively substitutes two hydrogen atoms of an L-tyrosine residue with two chlorine atoms." [PubMed:18688235]
synonym	"Cl2Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "68.88"
xref	DiffFormula: "C 0 Cl 2 H -2 N 0 O 0"
xref	DiffMono: "67.922055"
xref	Formula: "C 9 Cl 2 H 7 N 1 O 2"
xref	MassAvg: "232.06"
xref	MassMono: "230.985384"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00987 chlorinated tyrosine ! chlorinated tyrosine

2.1038. MOD:01038 norleucine (Nle)

Table 1040. Term [MOD:01038]
id	MOD:01038
name	norleucine (Nle)
def	"OBSOLETE because this represents a free amino acid and the corresponding residue is MOD:01026." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 131.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1039. MOD:01039 hydroxy aspartyl

Table 1041. Term [MOD:01039]
id	MOD:01039
name	hydroxy aspartyl
def	"OBSOLETE because redundant and identical to MOD:00036. Remap to MOD:00036." [PubMed:18688235]
comment	From DeltaMass:152 (name misspelled "aspartamyl", and formula incorrect, N and O reversed) Average Mass: 131 Formula:C4H5O1N4 Monoisotopic Mass Change:131.022 Average Mass Change:131.088
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 4 H 5 N 1 O 4"
xref	MassAvg: "131.09"
xref	MassMono: "131.021858"
xref	Origin: "D"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1040. MOD:01040 penicillamine residue

Table 1042. Term [MOD:01040]
id	MOD:01040
name	penicillamine residue
def	"A protein modification that inserts or replaces a residue with a penicillamine." [DeltaMass:154]
comment	From DeltaMass: Name misspelled 'bb-dimethyl cystenyl'. No citation provided.
synonym	"2-amino-3-mercapto-3-methylbutanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-3-methyl-3-sulfanylbutanoic acid" EXACT PSI-MOD-alternate []
synonym	"3,3-dimethylcysteine" EXACT PSI-MOD-alternate []
synonym	"3-mercapto-L-valine" EXACT PSI-MOD-alternate []
synonym	"beta,beta-dimethylcysteine" EXACT DeltaMass-label []
synonym	"Pen" EXACT DeltaMass-label []
synonym	"Pen" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.040485"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00850 unnatural residue ! unnatural residue

2.1041. MOD:01041 benzyloxycarbonyl modified residue

Table 1043. Term [MOD:01041]
id	MOD:01041
name	benzyloxycarbonyl modified residue
def	"A protein modification that effectively substitutes a benzyloxycarbonyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Z" EXACT DeltaMass-label []
xref	DiffAvg: "134.13"
xref	DiffFormula: "C 8 H 6 O 2"
xref	DiffMono: "134.036779"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1042. MOD:01042 adamantyl modified residue

Table 1044. Term [MOD:01042]
id	MOD:01042
name	adamantyl modified residue
def	"A protein modification that effectively substitutes a adamantyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Ada" EXACT DeltaMass-label []
xref	DiffAvg: "134.22"
xref	DiffFormula: "C 10 H 14"
xref	DiffMono: "134.109550"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1043. MOD:01043 p-nitrobenzyl ester modified residue

Table 1045. Term [MOD:01043]
id	MOD:01043
name	p-nitrobenzyl ester modified residue
def	"A protein modification that effectively substitutes a p-nitrobenzyl group for the hydrogen atom of a carboxyl group." [DeltaMass:0]
synonym	"ONb" EXACT DeltaMass-label []
xref	DiffAvg: "135.12"
xref	DiffFormula: "C 7 H 5 N 1 O 2"
xref	DiffMono: "135.032028"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1044. MOD:01044 N-methyl glutamyl

Table 1046. Term [MOD:01044]
id	MOD:01044
name	N-methyl glutamyl
def	"OBSOLETE because redundant and identical to MOD:00080. Remap to MOD:00080." [DeltaMass:166]
comment	From DeltaMass with no citation. Formula:C6H10O2N2 (name misspelled, formula for N5-methylglutaminyl, rather than N2-methylglutamyl)
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Q"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1045. MOD:01045 3',5'-dichloro-L-tyrosine

Table 1047. Term [MOD:01045]
id	MOD:01045
name	3',5'-dichloro-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3',5'-dichloro-L-tyrosine." [PubMed:18688235]
synonym	"3',5'-Cl2Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "68.88"
xref	DiffFormula: "C 0 Cl 2 H -2 N 0 O 0"
xref	DiffMono: "67.922055"
xref	Formula: "C 9 Cl 2 H 7 N 1 O 2"
xref	MassAvg: "232.06"
xref	MassMono: "230.985384"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01037 dichlorinated tyrosine ! dichlorinated tyrosine

2.1046. MOD:01046 3'-chloro-L-tyrosine

Table 1048. Term [MOD:01046]
id	MOD:01046
name	3'-chloro-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3'-chloro-L-tyrosine." [PubMed:18688235]
synonym	"3'-ClTyr" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 9 Cl 1 H 8 N 1 O 2"
xref	MassAvg: "197.62"
xref	MassMono: "197.024356"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01028 monochlorinated L-tyrosine ! monochlorinated L-tyrosine

2.1047. MOD:01047 monohydroxylated lysine

Table 1049. Term [MOD:01047]
id	MOD:01047
name	monohydroxylated lysine
def	"A protein modification that effectively converts an L-lysine residue to a monohydroxylated lysine." [DeltaMass:168, OMSSA:60, UniMod:35#K]
comment	From DeltaMass: Average Mass: 144 Abbreviation:-Hyl- Formula:C6H12N2O2 Monoisotopic Mass Change:144.09 Average Mass Change:144.174.
subset	PSI-MOD-slim
synonym	"Hy1Lys" EXACT PSI-MOD-label []
synonym	"Hydroxy Lysyl (-Hyl-)" EXACT DeltaMass-label []
synonym	"hydroxylationk" EXACT OMSSA-label []
synonym	"Oxidation" RELATED PSI-MS-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 2 O 2"
xref	MassAvg: "144.17"
xref	MassMono: "144.089878"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00681 hydroxylated lysine ! hydroxylated lysine

2.1048. MOD:01048 2-pyrrolidone-5-carboxylic acid

Table 1050. Term [MOD:01048]
id	MOD:01048
name	2-pyrrolidone-5-carboxylic acid
def	"A protein modification that effectively converts a source amino acid residue to 2-pyrrolidone-5-carboxylic acid." [PubMed:18688235]
comment	From DeltaMass: Average Mass: -18 Average Mass Change: -18.01 References:The conversion of glutamic acid to pyroglutamic was reported for the beta-amiloid protein. Miller et al. Arch. Biochem. Biophy. (1993) 301, 41-52.
subset	PSI-MOD-slim
synonym	"PyrGlu" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 6 N 1 O 2"
xref	MassAvg: "112.11"
xref	MassMono: "112.039853"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "N-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1049. MOD:01049 halogenated histidine

Table 1051. Term [MOD:01049]
id	MOD:01049
name	halogenated histidine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-histidine residue with a halogen atom." [PubMed:18688235]
synonym	"HalHis" EXACT PSI-MOD-label []
xref	Origin: "H"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1050. MOD:01050 pyridyl alanyl

Table 1052. Term [MOD:01050]
id	MOD:01050
name	pyridyl alanyl
def	"modification from DeltaMass" [DeltaMass:180]
comment	From DeltaMass: Average Mass: 148 Formula:C8H8O2N1 Monoisotopic Mass Change:148.064 Average Mass Change:148.165
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "A"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1051. MOD:01051 2-nitrobenzoyl

Table 1053. Term [MOD:01051]
id	MOD:01051
name	2-nitrobenzoyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 149
synonym	"NBz" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1052. MOD:01052 dimethoxybenzyl Trp

Table 1054. Term [MOD:01052]
id	MOD:01052
name	dimethoxybenzyl Trp
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 150
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1053. MOD:01053 2-nitrophenylsulphenyl

Table 1055. Term [MOD:01053]
id	MOD:01053
name	2-nitrophenylsulphenyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 153
synonym	"Nps" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1054. MOD:01054 4-toluenesulfonyl

Table 1056. Term [MOD:01054]
id	MOD:01054
name	4-toluenesulfonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 154
synonym	"4-toluenesulphonyl" EXACT DeltaMass-label []
synonym	"Tos" EXACT DeltaMass-label []
synonym	"Tosyl" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1055. MOD:01055 3-nitro-2-pyridinesulfenyl

Table 1057. Term [MOD:01055]
id	MOD:01055
name	3-nitro-2-pyridinesulfenyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 154
synonym	"Npys" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1056. MOD:01056 (79)Br labeled 3',5'-dibromotyrosine

Table 1058. Term [MOD:01056]
id	MOD:01056
name	(79)Br labeled 3',5'-dibromotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 156
xref	DiffAvg: "155.82"
xref	DiffFormula: "(79)Br 2 C 0 H -2 N 0 O 0"
xref	DiffMono: "155.821024"
xref	Formula: "(79)Br 2 C 9 H 7 N 1 O 2"
xref	MassAvg: "318.88"
xref	MassMono: "318.884353"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01023 3',5'-dibromo-L-tyrosine ! 3',5'-dibromo-L-tyrosine

2.1057. MOD:01057 (79)Br and (81)Br labeled 3',5'-dibromotyrosine

Table 1059. Term [MOD:01057]
id	MOD:01057
name	(79)Br and (81)Br labeled 3',5'-dibromotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 158
xref	DiffAvg: "157.82"
xref	DiffFormula: "(79)Br 1 (81)Br 1 C 0 H -2 N 0 O 0"
xref	DiffMono: "157.818978"
xref	Formula: "(79)Br 1 (81)Br 1 C 9 H 7 N 1 O 2"
xref	MassAvg: "320.88"
xref	MassMono: "320.882306"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01023 3',5'-dibromo-L-tyrosine ! 3',5'-dibromo-L-tyrosine

2.1058. MOD:01058 dichlorobenzyl

Table 1060. Term [MOD:01058]
id	MOD:01058
name	dichlorobenzyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 159
synonym	"Dcb" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1059. MOD:01059 (81)Br labeled 3',5'-dibromotyrosine

Table 1061. Term [MOD:01059]
id	MOD:01059
name	(81)Br labeled 3',5'-dibromotyrosine
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 160
xref	DiffAvg: "159.82"
xref	DiffFormula: "(81)Br 2 C 0 H -2 N 0 O 0"
xref	DiffMono: "159.816931"
xref	Formula: "(81)Br 2 C 9 H 7 N 1 O 2"
xref	MassAvg: "322.88"
xref	MassMono: "322.880260"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01023 3',5'-dibromo-L-tyrosine ! 3',5'-dibromo-L-tyrosine

2.1060. MOD:01060 S-carboxamidomethyl-L-cysteine

Table 1062. Term [MOD:01060]
id	MOD:01060
name	S-carboxamidomethyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxamidomethyl-L-cysteine." [DeltaMass:196, DeltaMass:337, OMSSA:3, PubMed:10504701, PubMed:11510821, PubMed:12422359, PubMed:18306178, UniMod:4#C]
comment	From DeltaMass: (name misspelled "Carboxyamidomethyl Cystenyl") [JSG].
subset	PSI-MOD-slim
synonym	"amidocarboxymethylcysteine" EXACT DeltaMass-label []
synonym	"CamC" EXACT PSI-MOD-alternate []
synonym	"CamCys" EXACT DeltaMass-label []
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"carbamidomethylc" EXACT OMSSA-label []
synonym	"carbamoylmethylcysteine" EXACT DeltaMass-label []
synonym	"Carboxamidomethyl (on Cysteine)" EXACT DeltaMass-label []
synonym	"Carboxyamidomethyl Cystenyl" EXACT DeltaMass-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
synonym	"S-carbamoylmethyl-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1 S 0"
xref	DiffMono: "57.021464"
xref	Formula: "C 5 H 8 N 2 O 2 S 1"
xref	MassAvg: "160.19"
xref	MassMono: "160.030649"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1061. MOD:01061 S-carboxymethyl-L-cysteine

Table 1063. Term [MOD:01061]
id	MOD:01061
name	S-carboxymethyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxymethyl-L-cysteine." [DeltaMass:0, DeltaMass:197, OMSSA:2, UniMod:6#C]
comment	From DeltaMass with no citation, name misspelled "Carboxymethyl Cystenyl", and formula incorrect, N and O reversed: Average Mass: 161 Abbreviation: -Cmc- Formula: C5H7O1N3S1 Monoisotopic Mass Change: 161.015 Average Mass Change: 161.179 [JSG].
subset	PSI-MOD-slim
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Carboxymethyl cysteine" EXACT DeltaMass-label []
synonym	"Carboxymethyl Cystenyl" EXACT DeltaMass-label []
synonym	"carboxymethylc" EXACT OMSSA-label []
synonym	"CmC" EXACT PSI-MOD-alternate []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 N 0 O 2 S 0"
xref	DiffMono: "58.005479"
xref	Formula: "C 5 H 7 N 1 O 3 S 1"
xref	MassAvg: "161.18"
xref	MassMono: "161.014664"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1062. MOD:01062 carboxymethyl cysteinyl

Table 1064. Term [MOD:01062]
id	MOD:01062
name	carboxymethyl cysteinyl
def	"OBSOLETE because duplicate and redundant with MOD:01061. Remap to MOD:01061" [DeltaMass:197]
comment	From DeltaMass:197 (Name misspelled "cystenyl", and formula incorrect, N and O reversed) Abbreviation:-Cmc- Formula:C5H7O1N3S1 Monoisotopic Mass Change:161.015 Average Mass Change:161.179
synonym	"Carboxymethyl Cystenyl" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 7 N 3 O 1 S 1"
xref	MassAvg: "157.19"
xref	MassMono: "157.030983"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1063. MOD:01063 monomethylated phenylalanine

Table 1065. Term [MOD:01063]
id	MOD:01063
name	monomethylated phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to a monomethylated phenylalanine." [DeltaMass:198]
comment	From DeltaMass: Average Mass: 161 Formula: C10H11O1N1 Monoisotopic Mass Change: 161.084 Average Mass Change: 161.205. No citation provided. It is not obvious whether the DeltaMass entry is supposed to represent N-methylphenylalanine, alpha-methylphenylalanine, 2'-, 3'-, or 4'-methylphenylalanine [JSG].
subset	PSI-MOD-slim
synonym	"NMePhe" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 10 H 11 N 1 O 1"
xref	MassAvg: "161.20"
xref	MassMono: "161.084064"
xref	Origin: "F"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00717 methylated phenylalanine ! methylated phenylalanine

2.1064. MOD:01064 inositol

Table 1066. Term [MOD:01064]
id	MOD:01064
name	inositol
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 162
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1065. MOD:01065 hexose glycated N-terminal

Table 1067. Term [MOD:01065]
id	MOD:01065
name	hexose glycated N-terminal
def	"A modification produced in a non-enzymatic reaction between a carbohydrate carbonyl group (C1 of aldohexose or C2 of fructose) and a protein N-terminal amino group to form a Schiff-base or an Amadori ketosamine (or aminoketose) residue adduct." [DeltaMass:0, UniMod:41#N-term]
comment	From DeltaMass: Average Mass: 162
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "N-term"
is_a	MOD:00767 glycated residue ! glycated residue

2.1066. MOD:01066 halogenated phenylalanine

Table 1068. Term [MOD:01066]
id	MOD:01066
name	halogenated phenylalanine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-phenylalanine residue with a halogen atom." [PubMed:18688235]
synonym	"HalPhe" EXACT PSI-MOD-label []
xref	Origin: "F"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.1067. MOD:01067 linker attached to peptide in Fmoc peptide synthesis

Table 1069. Term [MOD:01067]
id	MOD:01067
name	linker attached to peptide in Fmoc peptide synthesis
def	"modification from DeltaMass" [DeltaMass:341]
comment	From DeltaMass: Average Mass: 162 Average Mass Change:162 Notes: (from the ABRF discussion list archive) There may be … things in the reagent K that would allow cleavage of the peptide to occur at the wrong place…in this case it removes the dimethoxybenzyl group first inactivating that site for cleavage, and it goes after tne next amide bond closer to the resin. Try the TFA/TIS/water/EDT cocktail…TFA = 92%, TIS =3%, and water is at 5%. .. had this issue on longer peptides.. and by increasing the amount of water a little bit… able to elminate this problem.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1068. MOD:01068 halogenated tryptophan

Table 1070. Term [MOD:01068]
id	MOD:01068
name	halogenated tryptophan
def	"A protein modification that effectively substitutes a hydrogen atom of an L-tryptophan residue with a halogen atom." [PubMed:18688235]
synonym	"HalTrp" EXACT PSI-MOD-label []
xref	Origin: "W"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1069. MOD:01069 2,4-dinitrophenyl modified residue

Table 1071. Term [MOD:01069]
id	MOD:01069
name	2,4-dinitrophenyl modified residue
def	"A protein modification that effectively substitutes a 2,4-dinitrophenyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Dnp" EXACT DeltaMass-label []
xref	DiffAvg: "166.09"
xref	DiffFormula: "C 6 H 2 N 2 O 4"
xref	DiffMono: "166.001457"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1070. MOD:01070 pentafluorophenyl modified residue

Table 1072. Term [MOD:01070]
id	MOD:01070
name	pentafluorophenyl modified residue
def	"A protein modification that effectively substitutes a pentafluorophenyl group for a hydrogen atom." [DeltaMass:0]
comment	From DeltaMass: name mispelled "pentaflourophenyl"
synonym	"Pfp" EXACT DeltaMass-label []
xref	DiffAvg: "166.05"
xref	DiffFormula: "C 6 F 5 H -1"
xref	DiffMono: "165.984191"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1071. MOD:01071 diphenylmethyl modified residue

Table 1073. Term [MOD:01071]
id	MOD:01071
name	diphenylmethyl modified residue
def	"A protein modification that effectively substitutes a diphenylmethyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Dpm" EXACT DeltaMass-label []
xref	DiffAvg: "166.22"
xref	DiffFormula: "C 13 H 10"
xref	DiffMono: "166.078250"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1072. MOD:01072 monopotassium salt

Table 1074. Term [MOD:01072]
id	MOD:01072
name	monopotassium salt
def	"A protein modification that effectively substitutes one potassium atom for one hydrogen atom." [DeltaMass:0]
subset	PSI-MOD-slim
synonym	"K1Res" EXACT PSI-MOD-label []
xref	DiffAvg: "38.09"
xref	DiffFormula: "H -1 K 1"
xref	DiffMono: "37.955882"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00849 potassium containing modified residue ! potassium containing modified residue

2.1073. MOD:01073 2-chlorobenzyloxycarbonyl modified residue

Table 1075. Term [MOD:01073]
id	MOD:01073
name	2-chlorobenzyloxycarbonyl modified residue
def	"A protein modification that effectively substitutes a 2-chlorobenzyloxycarbonyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Clz" EXACT DeltaMass-label []
xref	DiffAvg: "169.58"
xref	DiffFormula: "C 8 Cl 1 H 6 O 2"
xref	DiffMono: "169.005632"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1074. MOD:01074 napthylacetyl modified residue

Table 1076. Term [MOD:01074]
id	MOD:01074
name	napthylacetyl modified residue
def	"A protein modification that effectively substitutes a napthylacetyl group for a hydrogen atom." [DeltaMass:0]
xref	DiffAvg: "169.20"
xref	DiffFormula: "C 12 H 9 O 1"
xref	DiffMono: "169.065340"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1075. MOD:01075 mercury containing modified residue

Table 1077. Term [MOD:01075]
id	MOD:01075
name	mercury containing modified residue
def	"A protein modification that effectively substitutes a mercury atom or a cluster containing mercury for hydrogen atoms, or that coordinates a mercury ion." [PubMed:18688235]
synonym	"HgRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.1076. MOD:01076 N-methyl arginyl

Table 1078. Term [MOD:01076]
id	MOD:01076
name	N-methyl arginyl
def	"modification from DeltaMass - OBSOLETE because redundant and identical to MOD:00414. Remap to MOD:00414." [DeltaMass:215]
comment	From DeltaMass: Average Mass: 170 Formula:C7H14O4N1 Monoisotopic Mass Change:170.117 Average Mass Change:170.215
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 7 H 14 N 4 O 1"
xref	MassAvg: "170.22"
xref	MassMono: "170.116761"
xref	Origin: "R"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1077. MOD:01077 ethanedithiol/TFA cyclic adduct

Table 1079. Term [MOD:01077]
id	MOD:01077
name	ethanedithiol/TFA cyclic adduct
def	"modification from DeltaMass" [DeltaMass:216]
comment	From DeltaMass: Average Mass: 172 Average Mass Change:172 References:[1]. Sieber,P.(1987) Modification of tryptophan residues during acidolysis of4-methoxy-2,3,6-trimethylbenzenesulfonyl groups. Effects of scavengers. Tetrahedron Lett., 28(15),1637-1640. Notes: TFA-cyclic dithioketal by-product is formed when Trp-containing peptide is subjected to prolonged TFA/EDT treatment [1]. See structure at http://www.abrf.org/images/misc/dmass172.gif. Additional discussion of this adduct, and how to avoid it, can befound in Methods in Enzymology 289, 67 (1997)
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1078. MOD:01078 S-(2-aminoethyl)-3-methylcysteine (Thr)

Table 1080. Term [MOD:01078]
id	MOD:01078
name	S-(2-aminoethyl)-3-methylcysteine (Thr)
def	"A protein modification that effectively converts an L-threonine residue to S-(2-aminoethyl)-3-methylcysteine." [PubMed:12923550, UniMod:472#T]
comment	From DeltaMass: Average Mass: 146 Abbreviation:-AECys_ Formula:C5H10O2N1S1 Monoisotopic Mass Change:146.051 Average Mass Change:146.214 References:PE Sciex.
synonym	"2-amino-3-(2-aminoethyl)sulfanyl-3-methylbutanoic acid" EXACT PSI-MOD-alternate []
synonym	"AEC-MAEC" RELATED UniMod-interim []
synonym	"beta-methylaminoethylcysteine" RELATED UniMod-description []
synonym	"S-aminoethyl-3-methylcysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "59.13"
xref	DiffFormula: "C 2 H 5 N 1 O -1 S 1"
xref	DiffMono: "59.019356"
xref	Formula: "C 6 H 12 N 2 O 1 S 1"
xref	MassAvg: "160.24"
xref	MassMono: "160.067034"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1079. MOD:01079 S-(acetylamino)methyl-L-cysteine

Table 1081. Term [MOD:01079]
id	MOD:01079
name	S-(acetylamino)methyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-[(acetylamino)methyl]-L-cysteine." [DeltaMass:218, PubMed:8572278]
comment	From DeltaMass: (name misspelled "Acetamidomethyl Cystenyl") Average Mass: 174 Formula: C 6 H 10 O 2 N 2 S 1 Monoisotopic Mass Change: 174.046 Average Mass Change: 174.221. [These are aggregate masses, not delta masses.] See Organic Syntheses, Coll. Vol. 6, p.5 (1988); Vol. 59, p.190 (1979); http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=cv6p0005 [JSG].
synonym	"Acetamidomethyl Cystenyl" EXACT DeltaMass-label []
synonym	"Acm-Cys" EXACT PSI-MOD-alternate []
synonym	"N-(hydroxymethyl)acetamide derivatized L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-(acetamido)methyl-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "71.08"
xref	DiffFormula: "C 3 H 5 N 1 O 1 S 0"
xref	DiffMono: "71.037114"
xref	Formula: "C 6 H 10 N 2 O 2 S 1"
xref	MassAvg: "174.22"
xref	MassMono: "174.046299"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1080. MOD:01080 acrylamidyl cysteinyl

Table 1082. Term [MOD:01080]
id	MOD:01080
name	acrylamidyl cysteinyl
def	"modification from DeltaMass" [DeltaMass:219]
comment	From DeltaMass: (name misspelled "Acrylamidyl Cystenyl") Average Mass: 174 Formula: C6H10O2N2S1 Monoisotopic Mass Change: 174.046 Average Mass Change: 174.221
synonym	"Acrylamidyl Cystenyl" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 10 N 2 O 2 S 1"
xref	MassAvg: "174.22"
xref	MassMono: "174.046299"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1081. MOD:01081 delta-glycosyloxy- (of lysine) or beta-glycosyloxy- (of phenylalanine or tyrosine)

Table 1083. Term [MOD:01081]
id	MOD:01081
name	delta-glycosyloxy- (of lysine) or beta-glycosyloxy- (of phenylalanine or tyrosine)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 177. CAUTION - mass does not match formula.
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1082. MOD:01082 4-glycosyloxy- (hexosyl, C6) (of proline)

Table 1084. Term [MOD:01082]
id	MOD:01082
name	4-glycosyloxy- (hexosyl, C6) (of proline)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 177. Caution: Formula does not match mass. The natural glycosylating sugar of hydroxyproline is galactose.
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "C 11 H 17 N 1 O 6"
xref	MassAvg: "259.26"
xref	MassMono: "259.105587"
xref	Origin: "P"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1083. MOD:01083 O-benzyl-L-serine

Table 1085. Term [MOD:01083]
id	MOD:01083
name	O-benzyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-benzyl-L-serine." [DeltaMass:0]
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "C 10 H 11 N 1 O 2"
xref	MassAvg: "177.20"
xref	MassMono: "177.078979"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01008 benzyl (Bzl) and benzyl ester (OBzl) modified residue ! benzyl (Bzl) and benzyl ester (OBzl) modified residue

2.1084. MOD:01084 iodoacetic acid derivatized amino-terminal residue

Table 1086. Term [MOD:01084]
id	MOD:01084
name	iodoacetic acid derivatized amino-terminal residue
def	"A protein modification that by reaction of iodoacetic acid effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a carboxymethyl group." [UniMod:6#N-term]
subset	PSI-MOD-slim
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Carboxymethyl (on Cysteine)" EXACT DeltaMass-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue

2.1085. MOD:01085 alpha-N-gluconoylation (His Tagged proteins)

Table 1087. Term [MOD:01085]
id	MOD:01085
name	alpha-N-gluconoylation (His Tagged proteins)
def	"modification from DeltaMass" [DeltaMass:226]
comment	From DeltaMass: Average Mass: 178 Formula: C6H10O6 Monoisotopic Mass Change: 178.05 Average Mass Change: 178.14 References: Geoghegan, K. F., H. B. Dixon, et al. (1999). Spontaneous alpha-N-6-phosphogluconoylation of a His tag in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins. Anal Biochem 267(1): 169-84.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1086. MOD:01086 p-nitrobenzyloxycarbonyl

Table 1088. Term [MOD:01086]
id	MOD:01086
name	p-nitrobenzyloxycarbonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 179
synonym	"4Nz" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1087. MOD:01087 2,4,5-trichlorophenyl modified residue

Table 1089. Term [MOD:01087]
id	MOD:01087
name	2,4,5-trichlorophenyl modified residue
def	"A protein modification that effectively substitutes a 2,4,5-trichlorophenyl group for a hydrogen atom." [DeltaMass:0]
xref	DiffAvg: "179.42"
xref	DiffFormula: "C 6 Cl 3 H 1"
xref	DiffMono: "177.914383"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1088. MOD:01088 2,4,6-trimethyloxybenzyl modified residue

Table 1090. Term [MOD:01088]
id	MOD:01088
name	2,4,6-trimethyloxybenzyl modified residue
def	"A protein modification that effectively substitutes a 2,4,6-trimethyloxybenzyl group for a hydrogen atom." [DeltaMass:0]
synonym	"Tmob" EXACT DeltaMass-label []
xref	DiffAvg: "180.20"
xref	DiffFormula: "C 10 H 12 O 3"
xref	DiffMono: "180.078644"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1089. MOD:01089 xanthyl

Table 1091. Term [MOD:01089]
id	MOD:01089
name	xanthyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 180
synonym	"Xan" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1090. MOD:01090 iodoacetamide derivatized amino-terminal residue

Table 1092. Term [MOD:01090]
id	MOD:01090
name	iodoacetamide derivatized amino-terminal residue
def	"A protein modification that by reaction of iodoacetamide effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a carboxamidomethyl group." [PubMed:11327326, PubMed:11510821, PubMed:12422359, UniMod:4#N-term]
subset	PSI-MOD-slim
synonym	"(carbamoylmethyl)amino" EXACT PSI-MOD-alternate []
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue

2.1091. MOD:01091 monochlorinated L-phenylalanine

Table 1093. Term [MOD:01091]
id	MOD:01091
name	monochlorinated L-phenylalanine
def	"A protein modification that effectively substitutes one hydrogen atom of an L-phenylalanine residue with one chlorine atom." [DeltaMass:233]
comment	From DeltaMass: Average Mass: 182 Formula:C9H8O1N1Cl1 Monoisotopic Mass Change:181.029 Average Mass Change:181.623
synonym	"Cl1Phe" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 9 Cl 1 H 8 N 1 O 1"
xref	MassAvg: "181.62"
xref	MassMono: "181.029442"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01066 halogenated phenylalanine ! halogenated phenylalanine
is_a	MOD:01911 monochlorinated residue ! monochlorinated residue

2.1092. MOD:01092 mesitylene-2-sulfonyl

Table 1094. Term [MOD:01092]
id	MOD:01092
name	mesitylene-2-sulfonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 182
synonym	"Mts" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1093. MOD:01093 isopropyl lysyl

Table 1095. Term [MOD:01093]
id	MOD:01093
name	isopropyl lysyl
def	"modification from DeltaMass" [DeltaMass:236]
comment	From DeltaMass: Average Mass: 184 Formula: C9H16O2N2 Monoisotopic Mass Change: 184.12 Average Mass Change: 184.24 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 9 H 16 N 2 O 2"
xref	MassAvg: "184.24"
xref	MassMono: "184.121178"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1094. MOD:01094 N6-carboxymethyl-L-lysine

Table 1096. Term [MOD:01094]
id	MOD:01094
name	N6-carboxymethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-carboxymethyl-L-lysine." [DeltaMass:237, UniMod:6#K]
comment	From DeltaMass:237 (with no citation, formula incorrect, N and O reversed) Average Mass: 186 Formula: C8H14O2N3 Monoisotopic Mass Change: 186.1 Average Mass Change: 186.211 [JSG].
subset	PSI-MOD-slim
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Carboxymethyl Lysyl" EXACT DeltaMass-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "C 8 H 14 N 2 O 3"
xref	MassAvg: "186.21"
xref	MassMono: "186.100442"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue

2.1095. MOD:01095 Matrix alpha cyano MH+

Table 1097. Term [MOD:01095]
id	MOD:01095
name	Matrix alpha cyano MH+
def	"Modification from DeltaMass. OBSOLETE because not an amino acid modification." [DeltaMass:240]
comment	From DeltaMass with no citation, formula incorrect, N and O reversed: Formula: C10H8O1N3 Monoisotopic Mass Change: 190.05 Average Mass Change: 190.18.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 10 H 8 N 1 O 3"
xref	MassAvg: "190.18"
xref	MassMono: "190.050418"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1096. MOD:01096 O-benzyl-L-threonine

Table 1098. Term [MOD:01096]
id	MOD:01096
name	O-benzyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-benzyl-L-threonine." [DeltaMass:0]
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "C 11 H 13 N 1 O 2"
xref	MassAvg: "191.23"
xref	MassMono: "191.094629"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01008 benzyl (Bzl) and benzyl ester (OBzl) modified residue ! benzyl (Bzl) and benzyl ester (OBzl) modified residue

2.1097. MOD:01097 S-benzyl-L-cysteine

Table 1099. Term [MOD:01097]
id	MOD:01097
name	S-benzyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-benzyl-L-cysteine." [DeltaMass:242]
comment	From DeltaMass: misspelled "Benzyl Cystenyl".
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "C 10 H 11 N 1 O 1 S 1"
xref	MassAvg: "193.26"
xref	MassMono: "193.056135"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01008 benzyl (Bzl) and benzyl ester (OBzl) modified residue ! benzyl (Bzl) and benzyl ester (OBzl) modified residue

2.1098. MOD:01098 naphthylalanine residue

Table 1100. Term [MOD:01098]
id	MOD:01098
name	naphthylalanine residue
def	"A protein modification that inserts or replaces a residue with a naphthylalanine." [DeltaMass:243]
comment	From DeltaMass: Average Mass: 197 Formula: C13H11O1N1 Monoisotopic Mass Change: 197.084 Average Mass Change: 197.238. No citation provided. It is not obvious which isomer of naphthylalanine this DeltaMass entry is supposed to represent [JSG].
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 13 H 11 N 1 O 1"
xref	MassAvg: "197.24"
xref	MassMono: "197.084064"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00850 unnatural residue ! unnatural residue

2.1099. MOD:01099 succinyl beta-aspartyl anhydride

Table 1101. Term [MOD:01099]
id	MOD:01099
name	succinyl beta-aspartyl anhydride
def	"A protein modification that effectively converts an L-aspartic acid residue to succinyl beta-aspartyl anhydride." [DeltaMass:244]
comment	From DeltaMass with no citation (name misspelled "aspartamyl", and formula incorrect, N and O reversed) Average Mass: 198 Formula: C8H8O1N5 Monoisotopic Mass Change: 198.04 Average Mass Change: 198.156 [JSG].
synonym	"succinyl aspartamyl" EXACT DeltaMass-label []
xref	DiffAvg: "82.06"
xref	DiffFormula: "C 4 H 2 N 0 O 2"
xref	DiffMono: "82.005479"
xref	Formula: "C 8 H 8 N 1 O 5"
xref	MassAvg: "198.15"
xref	MassMono: "198.040247"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01029 succinylated residue ! succinylated residue

2.1100. MOD:01100 HMP (hydroxymethylphenyl)/TFA adduct

Table 1102. Term [MOD:01100]
id	MOD:01100
name	HMP (hydroxymethylphenyl)/TFA adduct
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 201 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1101. MOD:01101 S-Farnesyl-

Table 1103. Term [MOD:01101]
id	MOD:01101
name	S-Farnesyl-
def	"OBSOLETE because erroneous and apparently redundant to MOD:00111. Remap to MOD:00111." [DeltaMass:0]
comment	Modification from DeltaMass: Average Mass: 206. This entry with no other information available appears to be the same as the entry at 204 for "Farnesylation" but with an incorrect mass.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1102. MOD:01102 myristoylation-4H (two double bonds)

Table 1104. Term [MOD:01102]
id	MOD:01102
name	myristoylation-4H (two double bonds)
def	"OBSOLETE because redundant and identical to MOD:00504. Remap to MOD:00504." [DeltaMass:348]
comment	From DeltaMass: Average Mass: 206 Formula: C14 H22 O1 Monoisotopic Mass Change: 206.167 Average Mass Change: 206.324 References: Neubert TA, Johnson RS, Hurley JB, Walsh KA (1992). The rod transducin alpha subunit amino terminus is heterogeneously fatty acylated. J Biol Chem. 267(26), 18274-7. Notes: Modification of protein N-terminus with (cis,cis-delta 5, delta 8)-tetradecadienoyl group (myristoylation with 2 double bonds)
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1103. MOD:01103 myristoleylation (one double bond)

Table 1105. Term [MOD:01103]
id	MOD:01103
name	myristoleylation (one double bond)
def	"OBSOLETE because redundant and identical to MOD:00503. Remap to MOD:00503." [DeltaMass:0]
comment	From DeltaMass with no citation or formula: Average Mass: 208.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1104. MOD:01104 4-methoxy-2,3,6-trimethylbenzenesulfonyl

Table 1106. Term [MOD:01104]
id	MOD:01104
name	4-methoxy-2,3,6-trimethylbenzenesulfonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 212 with no citation.
synonym	"Mtr" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1105. MOD:01105 2-bromobenzyloxycarbonyl

Table 1107. Term [MOD:01105]
id	MOD:01105
name	2-bromobenzyloxycarbonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 213 with no citation.
synonym	"BrZ" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1106. MOD:01106 N-formyl-L-tryptophan

Table 1108. Term [MOD:01106]
id	MOD:01106
name	N-formyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N-formyl-L-tryptophan." [DeltaMass:0]
comment	From DeltaMass with no citation or formula: Average Mass: 214. It is not clear what this is supposed to represent. The mass corresponds to an N-formyl tryptophan (either N2 or N1'), but neither of these modifications has been reported as commonly encountered. It may have been confused with N'-formyl-L-kynurenine, see MOD:00464 [JSG]
synonym	"formyl tryptophanyl" EXACT DeltaMass-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 12 H 10 N 2 O 2"
xref	MassAvg: "214.22"
xref	MassMono: "214.074228"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1107. MOD:01107 O5-benzyl-L-glutamate

Table 1109. Term [MOD:01107]
id	MOD:01107
name	O5-benzyl-L-glutamate
def	"A protein modification that effectively converts an L-glutamic acid residue to O5-benzyl-L-glutamate." [DeltaMass:258]
comment	From DeltaMass with no citation: (formula incorrect, N and O reversed; mass incorrect, aggregate not delta) Average Mass: 219 Formula: C12H13O1N3 Monoisotopic Mass Change: 219.241 Average Mass Change: 219.09 [JSG].
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "C 12 H 13 N 1 O 3"
xref	MassAvg: "219.24"
xref	MassMono: "219.089543"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01008 benzyl (Bzl) and benzyl ester (OBzl) modified residue ! benzyl (Bzl) and benzyl ester (OBzl) modified residue

2.1108. MOD:01108 2-amino-5-(4-methoxyphenyl)-5-oxopentanoic acid (Glu)

Table 1110. Term [MOD:01108]
id	MOD:01108
name	2-amino-5-(4-methoxyphenyl)-5-oxopentanoic acid (Glu)
def	"A protein modification that effectively converts an L-glutamic acid residue to 2-amino-5-(4-methoxyphenyl)-5-oxopentanoic acid, glutamtic acid anisole adduct." [DeltaMass:259]
comment	From DeltaMass with no citation: (formula incorrect, N and O reversed; mass incorrect, aggregate not delta) Average Mass: 219 Formula: C12H13O1N3 Monoisotopic Mass Change: 219.241 Average Mass Change: 219.09 [JSG].
synonym	"anisole adducted glutamyl" EXACT DeltaMass-label []
xref	DiffAvg: "90.13"
xref	DiffFormula: "C 7 H 6"
xref	DiffMono: "90.046950"
xref	Formula: "C 12 H 13 N 1 O 3"
xref	MassAvg: "219.24"
xref	MassMono: "219.089543"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01007 anisyl modified residue ! anisyl modified residue

2.1109. MOD:01109 9-fluorenylmethyloxycarbonyl (Fmoc)

Table 1111. Term [MOD:01109]
id	MOD:01109
name	9-fluorenylmethyloxycarbonyl (Fmoc)
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 222 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1110. MOD:01110 isoprenylated cysteine

Table 1112. Term [MOD:01110]
id	MOD:01110
name	isoprenylated cysteine
def	"A protein modification that effectively replaces a hydrogen atom of an L-cysteine residue with a group derived from an isoprene polymer, such as a geranyl (C10), farnesyl (C15) or geranylgeranyl (C20)." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"IpCys" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00703 isoprenylated residue ! isoprenylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1111. MOD:01111 dimethoxybenzhydryl modified residue

Table 1113. Term [MOD:01111]
id	MOD:01111
name	dimethoxybenzhydryl modified residue
def	"A protein modification that effectively substitutes a dimethoxybenzhydryl group for a hydrogen atom." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 226 with no citation. A reagent, typically 4,4'-dimethoxybenzhydryl chloride, used as a protecting group for the carboxamido group of asparagine and glutamine during chemical peptide synthesis [JSG].
synonym	"4,4'-dimethoxybenzhydryl" EXACT PSI-MOD-alternate []
synonym	"bis(4-methoxyphenyl)methyl" EXACT PSI-MOD-alternate []
synonym	"Mbh" EXACT DeltaMass-label []
xref	DiffAvg: "226.27"
xref	DiffFormula: "C 15 H 14 O 2"
xref	DiffMono: "226.099380"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1112. MOD:01112 nicotinoyl lysine

Table 1114. Term [MOD:01112]
id	MOD:01112
name	nicotinoyl lysine
def	"modification from DeltaMass" [DeltaMass:266]
comment	From DeltaMass: (name misspelled "nicotinyl"; formula incorrect, N and O reversed; mass incorrect, aggregate not delta) Average Mass: 233 Formula: C12H15O3N2 Monoisotopic Mass Change: 233.116 Average Mass Change: 233.271
synonym	"nicotinyl lysyl" EXACT DeltaMass-label []
xref	DiffAvg: "105.10"
xref	DiffFormula: "C 6 H 3 N 1 O 1"
xref	DiffMono: "105.021464"
xref	Formula: "C 12 H 15 N 3 O 2"
xref	MassAvg: "233.27"
xref	MassMono: "233.116427"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1113. MOD:01113 2-(p-biphenyl)isopropyl-oxycarbonyl

Table 1115. Term [MOD:01113]
id	MOD:01113
name	2-(p-biphenyl)isopropyl-oxycarbonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 238 with no citation.
synonym	"Bpoc" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1114. MOD:01114 triphenylmethyl

Table 1116. Term [MOD:01114]
id	MOD:01114
name	triphenylmethyl
def	"modification from DeltaMass" [DeltaMass:270]
comment	From DeltaMass: Average Mass: 242 Average Mass Change: 242.3 Notes: blocking group used in peptide synthesis for C,H,Q,N
synonym	"Trityl" EXACT DeltaMass-label []
synonym	"Trt" EXACT DeltaMass-label []
xref	DiffAvg: "242.32"
xref	DiffFormula: "C 19 H 14"
xref	DiffMono: "242.109550"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1115. MOD:01115 isoprenylated tryptophan

Table 1117. Term [MOD:01115]
id	MOD:01115
name	isoprenylated tryptophan
def	"A protein modification that effectively replaces a hydrogen atom of an L-tryptophan residue with a group derived from an isoprene polymer, such as a geranyl (C10), farnesyl (C15) or geranylgeranyl (C20)." [PubMed:18688235]
synonym	"IpTrp" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "W"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00703 isoprenylated residue ! isoprenylated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1116. MOD:01116 S-farnesyl-L-cysteine methyl ester

Table 1118. Term [MOD:01116]
id	MOD:01116
name	S-farnesyl-L-cysteine methyl ester
def	"A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine methyl ester." [PubMed:15609361, RESID:AA0102#var, RESID:AA0105#var]
subset	PSI-MOD-slim
synonym	"SFarnOMeCys" EXACT PSI-MOD-label []
xref	DiffAvg: "218.38"
xref	DiffFormula: "C 16 H 26 N 0 O 0 S 0"
xref	DiffMono: "218.203451"
xref	Formula: "C 19 H 32 N 1 O 2 S 1"
xref	MassAvg: "338.53"
xref	MassMono: "338.215375"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	has_functional_parent MOD:00111 S-farnesyl-L-cysteine ! S-farnesyl-L-cysteine
relationship	has_functional_parent MOD:00114 L-cysteine methyl ester ! L-cysteine methyl ester

2.1117. MOD:01117 pentamethyldihydrobenzofuransulfonyl

Table 1119. Term [MOD:01117]
id	MOD:01117
name	pentamethyldihydrobenzofuransulfonyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 252 with no citation.
synonym	"Pbf" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1118. MOD:01118 alpha-N-6-phosphogluconoylation (His Tagged proteins)

Table 1120. Term [MOD:01118]
id	MOD:01118
name	alpha-N-6-phosphogluconoylation (His Tagged proteins)
def	"modification from DeltaMass" [DeltaMass:275]
comment	From DeltaMass: Average Mass: 258 Formula: C6H10O6HPO3 Monoisotopic Mass Change: 258.01 Average Mass Change: 258.12 References: Geoghegan, K. F., H. B. Dixon, et al. (1999). Spontaneous alpha-N-6-phosphogluconoylation of a His tag in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins. Anal Biochem 267(1): 169-84.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1119. MOD:01119 S-geranylgeranyl-L-cysteine methyl ester

Table 1121. Term [MOD:01119]
id	MOD:01119
name	S-geranylgeranyl-L-cysteine methyl ester
def	"A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine methyl ester." [PubMed:1483450, PubMed:15609361, RESID:AA0104#var, RESID:AA0105#var]
subset	PSI-MOD-slim
synonym	"SGergerOMeCys" EXACT PSI-MOD-label []
xref	DiffAvg: "286.50"
xref	DiffFormula: "C 21 H 34 N 0 O 0 S 0"
xref	DiffMono: "286.266051"
xref	Formula: "C 24 H 40 N 1 O 2 S 1"
xref	MassAvg: "406.65"
xref	MassMono: "406.277976"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	has_functional_parent MOD:00113 S-geranylgeranyl-L-cysteine ! S-geranylgeranyl-L-cysteine
relationship	has_functional_parent MOD:00114 L-cysteine methyl ester ! L-cysteine methyl ester

2.1120. MOD:01120 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue

Table 1122. Term [MOD:01120]
id	MOD:01120
name	2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue
def	"A protein modification that is produced by formation of an adduct with 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride, Pmc chloride." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 266 Notes: blocking group for Arg in peptide synthesis. CAS:112160-39-1 [JSG].
synonym	"2,2,5,7,8-pentamethyl-3,4-dihydro-2H-chromene-6-sulfonyl" EXACT PSI-MOD-alternate []
synonym	"2,2,5,7,8-pentamethyl-6-chromansulfonyl" EXACT PSI-MOD-alternate []
synonym	"2,2,5,7,8-pentamethyl-chromane-6-sulfonyl" EXACT PSI-MOD-alternate []
synonym	"2,2,5,7,8-pentamethylchroman-6-sulfonyl" EXACT PSI-MOD-alternate []
synonym	"2,2,5,7,8-pentamethylchroman-6-sulphonyl" EXACT PSI-MOD-alternate []
synonym	"3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-benzopyran-6-sulfonyl" EXACT PSI-MOD-alternate []
synonym	"Pmc" EXACT DeltaMass-label []
synonym	"PmcRes" EXACT PSI-MOD-label []
xref	DiffAvg: "266.36"
xref	DiffFormula: "C 14 H 18 O 3 S 1"
xref	DiffMono: "266.097665"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01652 sulfonyl halide reagent derivatized residue ! sulfonyl halide reagent derivatized residue

2.1121. MOD:01121 monomethoxytrityl

Table 1123. Term [MOD:01121]
id	MOD:01121
name	monomethoxytrityl
def	"modification from DeltaMass" [DeltaMass:280]
comment	From DeltaMass: Average Mass: 272 Average Mass Change: 272
synonym	"Mmt" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1122. MOD:01122 5’phos dCytidinyl

Table 1124. Term [MOD:01122]
id	MOD:01122
name	5’phos dCytidinyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 289 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1123. MOD:01123 monoiodated tyrosine

Table 1125. Term [MOD:01123]
id	MOD:01123
name	monoiodated tyrosine
def	"OBSOLETE because redundant and identical to MOD:01123. Remap to MOD:01123." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 289
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1124. MOD:01124 aldohexosyl lysyl

Table 1126. Term [MOD:01124]
id	MOD:01124
name	aldohexosyl lysyl
def	"modification from DeltaMass" [DeltaMass:285]
comment	From DeltaMass: (formula incorrect, N and O reversed; mass incorrect, aggregate not delta) Average Mass: 290 Formula: C12H22O2N6 Monoisotopic Mass Change: 290.148 Average Mass Change: 290.317
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 N 0 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 12 H 22 N 2 O 6"
xref	MassAvg: "290.32"
xref	MassMono: "290.147786"
xref	Origin: "K"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1125. MOD:01125 5’phos dThymidinyl

Table 1127. Term [MOD:01125]
id	MOD:01125
name	5’phos dThymidinyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 304 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1126. MOD:01126 5’phos Cytidinyl

Table 1128. Term [MOD:01126]
id	MOD:01126
name	5’phos Cytidinyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 305 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1127. MOD:01127 5’phos Uridinyl

Table 1129. Term [MOD:01127]
id	MOD:01127
name	5’phos Uridinyl
def	"OBSOLETE because redundant and identical to MOD:01166. Remap to MOD:01166." [DeltaMass:292]
comment	From DeltaMass: Average Mass: 306 Formula: C9H11O2N8P1 Monoisotopic Mass Change: 306.025 Average Mass Change: 306.17
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1128. MOD:01128 N-glycolneuraminic acid

Table 1130. Term [MOD:01128]
id	MOD:01128
name	N-glycolneuraminic acid
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 307 with no citation.
synonym	"NeuGc" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1129. MOD:01129 5’phos dAdenosyl

Table 1131. Term [MOD:01129]
id	MOD:01129
name	5’phos dAdenosyl
def	"modification from DeltaMass" [DeltaMass:295]
comment	From DeltaMass: Average Mass: 313 Formula: C10H12O5N5P1 Monoisotopic Mass Change: 313.058 Average Mass Change: 313.211
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1130. MOD:01130 SucPhencarb Lysyl

Table 1132. Term [MOD:01130]
id	MOD:01130
name	SucPhencarb Lysyl
def	"modification from DeltaMass" [DeltaMass:297]
comment	From DeltaMass: Average Mass: 327 Formula: C17H17O3N4 Monoisotopic Mass Change: 327.122 Average Mass Change: 327.342
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1131. MOD:01131 5’phos dGuanosyl

Table 1133. Term [MOD:01131]
id	MOD:01131
name	5’phos dGuanosyl
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 329
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1132. MOD:01132 5’phos Adenosinyl

Table 1134. Term [MOD:01132]
id	MOD:01132
name	5’phos Adenosinyl
def	"OBSOLETE because redundant and identical to MOD:01165. Remap to MOD:01165." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 329
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1133. MOD:01133 S-12-hydroxyfarnesyl-L-cysteine methyl ester

Table 1135. Term [MOD:01133]
id	MOD:01133
name	S-12-hydroxyfarnesyl-L-cysteine methyl ester
def	"A protein modification that effectively converts an L-cysteine residue to S-12-hydroxyfarnesyl-L-cysteine methyl ester." [PubMed:17790543, RESID:AA0103#var, RESID:AA0105#var]
synonym	"S12HyFarnOMeCys" EXACT PSI-MOD-label []
xref	DiffAvg: "234.38"
xref	DiffFormula: "C 16 H 26 N 0 O 1 S 0"
xref	DiffMono: "234.198365"
xref	Formula: "C 19 H 32 N 1 O 3 S 1"
xref	MassAvg: "354.53"
xref	MassMono: "354.210290"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	has_functional_parent MOD:00112 S-12-hydroxyfarnesyl-L-cysteine ! S-12-hydroxyfarnesyl-L-cysteine
relationship	has_functional_parent MOD:00114 L-cysteine methyl ester ! L-cysteine methyl ester

2.1134. MOD:01134 fluorescein labelling of peptide N-terminal using NHS ester

Table 1136. Term [MOD:01134]
id	MOD:01134
name	fluorescein labelling of peptide N-terminal using NHS ester
def	"modification from DeltaMass" [DeltaMass:306]
comment	From DeltaMass: Average Mass: 359 Formula: C21H11O6 Monoisotopic Mass Change: 359.055 Average Mass Change: 359.315 Notes: Using the DHB matrix at low pH the carboxyl group and one of the oxygens on the flurorescein molecule are protinated so the delta mass is 2Da higher than most text book illustrations would indicate. See Bioconjugate Techniques by Greg Hermanson, Academic Press, page 305, figure 204. Text books of course just show the coupling reaction at neutral or basic pH.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1135. MOD:01135 Hex-HexNAc

Table 1137. Term [MOD:01135]
id	MOD:01135
name	Hex-HexNAc
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 365 with no citation.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1136. MOD:01136 dioctyl phthalate

Table 1138. Term [MOD:01136]
id	MOD:01136
name	dioctyl phthalate
def	"modification from DeltaMass" [DeltaMass:309]
comment	From DeltaMass: Average Mass: 391 Average Mass Change: 391 Notes: A common plasticizer, and, unfortunaltely, a common contaminate. A sodium adduct is often associated with this peak at 413.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1137. MOD:01137 N6-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-lysine

Table 1139. Term [MOD:01137]
id	MOD:01137
name	N6-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-lysine
def	"A protein modification that is produced by reaction of a lysine residue with 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride, Pmc chloride, to form N6-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-lysine." [DeltaMass:310]
comment	From DeltaMass: Average Mass: Formula: C20H30O2N4S1 Monoisotopic Mass Change: 394.192 Average Mass Change: 394.534
synonym	"PMC lysyl" EXACT DeltaMass-label []
synonym	"PmcLys" EXACT PSI-MOD-label []
xref	DiffAvg: "266.36"
xref	DiffFormula: "C 14 H 18 O 3 S 1"
xref	DiffMono: "266.097665"
xref	Formula: "C 20 H 30 N 2 O 4 S 1"
xref	MassAvg: "394.53"
xref	MassMono: "394.192628"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01120 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue ! 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue

2.1138. MOD:01138 Aedans Cystenyl

Table 1140. Term [MOD:01138]
id	MOD:01138
name	Aedans Cystenyl
def	"modification from DeltaMass" [DeltaMass:311]
comment	[probably aminoethyldansyl, JSG] From DeltaMass: (name misspelled "Aedans Cystenyl", and formula incorrect, N and O reversed) Average Mass: 409 Abbreviation: Aedans-Cys Formula: C17H19O3N5S2 Monoisotopic Mass Change: 409.077 Average Mass Change: 409.482
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1139. MOD:01139 dioctyl phthalate sodium adduct

Table 1141. Term [MOD:01139]
id	MOD:01139
name	dioctyl phthalate sodium adduct
def	"modification from DeltaMass" [DeltaMass:312]
comment	From DeltaMass: Mass: Average Mass Change: 413 Notes: A common plasticizer, and, unfortunaltely, a common contaminate. A sodium adduct is often associated with this peak at 413.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1140. MOD:01140 diiodinated tyrosine

Table 1142. Term [MOD:01140]
id	MOD:01140
name	diiodinated tyrosine
def	"A protein modification that effectively substitutes two hydrogen atoms of an L-tyrosine residue with two iodine atoms." [DeltaMass:0, OMSSA:35, PubMed:15627961, UniMod:130#Y]
subset	PSI-MOD-slim
synonym	"3,5-Diiodination (of Tyrosine)" EXACT DeltaMass-label []
synonym	"di-Iodination" RELATED UniMod-description []
synonym	"diiodinationy" EXACT OMSSA-label []
synonym	"Diiodo" RELATED PSI-MS-label []
synonym	"I2Tyr" EXACT PSI-MOD-label []
xref	DiffAvg: "251.79"
xref	DiffFormula: "C 0 H -2 I 2 N 0 O 0"
xref	DiffMono: "251.793295"
xref	Formula: "C 9 H 7 I 2 N 1 O 2"
xref	MassAvg: "414.97"
xref	MassMono: "414.856624"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00501 diiodinated residue ! diiodinated residue
is_a	MOD:00998 iodinated tyrosine ! iodinated tyrosine

2.1141. MOD:01141 omega-N-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine

Table 1143. Term [MOD:01141]
id	MOD:01141
name	omega-N-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine
def	"A protein modification that is produced by reaction with 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride, Pmc chloride, to form omega-N-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine." [DeltaMass:314]
comment	From DeltaMass: Average Mass: Formula: C20H30O4N4S1 Monoisotopic Mass Change: 422.199 Average Mass Change: 422.547
synonym	"PMC arginyl" EXACT DeltaMass-label []
synonym	"PmcArg" EXACT PSI-MOD-label []
xref	DiffAvg: "266.36"
xref	DiffFormula: "C 14 H 18 O 3 S 1"
xref	DiffMono: "266.097665"
xref	Formula: "C 20 H 30 N 4 O 4 S 1"
xref	MassAvg: "422.54"
xref	MassMono: "422.198776"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01120 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue ! 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride derivatized residue

2.1142. MOD:01142 S-15,16-dihydrobiliverdin-L-cysteine

Table 1144. Term [MOD:01142]
id	MOD:01142
name	S-15,16-dihydrobiliverdin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound 15,16-dihydrobiliverdin." [PubMed:10430868, PubMed:15504407, PubMed:1559975, PubMed:3208761, RESID:AA0428]
synonym	"(16R)-18-ethenyl-8,12-bis(2-carboxyethyl)-3-[(1R)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-2,7,13,17-tetramethyl-15,16-dihydrobilin-1,19(21H,24H)-dione" EXACT RESID-systematic []
synonym	"15,16-Dhbv" EXACT RESID-alternate []
synonym	"15,16-dihydrobiliverdin cysteine adduct" EXACT RESID-alternate []
synonym	"15,16-dihydrobiliverdin IXalpha" EXACT RESID-alternate []
synonym	"18-ethenyl-8,12-bis(2-carboxyethyl)-3-(2-(cysteinyl-S)-ethyl)-2,7,13,17-tetramethylbiladiene-ab-1,19(16H,21H)-dione" EXACT RESID-alternate []
synonym	"3'-cysteinyl-15,16-dihydrobiliverdin" EXACT RESID-alternate []
synonym	"3alpha-cysteinyl-15,16-dihydrobiliverdin" EXACT RESID-alternate []
synonym	"BINDING 15,16-dihydrobiliverdin (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"DBV" EXACT RESID-alternate []
synonym	"S-15,16-dihydrobiliverdin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "584.67"
xref	DiffFormula: "C 33 H 36 N 4 O 6 S 0"
xref	DiffMono: "584.263485"
xref	Formula: "C 36 H 41 N 5 O 7 S 1"
xref	MassAvg: "687.81"
xref	MassMono: "687.272670"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1143. MOD:01143 15,16-dihydrobiliverdin-bis-L-cysteine

Table 1145. Term [MOD:01143]
id	MOD:01143
name	15,16-dihydrobiliverdin-bis-L-cysteine
def	"A protein modification that effectively results from forming an adduct between two cysteine residues and the tetrapyrrole compound 15,16-dihydrobiliverdin." [PubMed:1559975, PubMed:2222853, PubMed:3208761, PubMed:8420941, RESID:AA0429]
comment	Cross-link 2.
synonym	"(16R)-8,12-bis(2-carboxyethyl)-3-[2-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-18-[(1Xi)-1-(((2R)-2-amino-2-carboxy)ethylsulfanyl)ethyl]-2,7,13,17-tetramethyl-15,16-dihydrobilin-1,19(21H,24H)-dione" EXACT RESID-systematic []
synonym	"15,16-Dhbv" EXACT RESID-alternate []
synonym	"15,16-dihydrobiliverdin cysteine adduct" EXACT RESID-alternate []
synonym	"15,16-dihydrobiliverdin IXalpha" EXACT RESID-alternate []
synonym	"15,16-dihydrobiliverdin-bis-L-cysteine" EXACT RESID-name []
synonym	"3'',18'-biscysteinyl-15,16-dihydrobiliverdin" EXACT RESID-alternate []
synonym	"3beta,18alpha-biscysteinyl-15,16-dihydrobiliverdin" EXACT RESID-alternate []
synonym	"8,12-bis(2-carboxyethyl)-3-(2-(cysteinyl-S)-ethyl)-18-(1-(cysteinyl-S)-ethyl)-2,7,13,17-tetramethylbiladiene-ab-1,19(16H,21H)-dione" EXACT RESID-alternate []
synonym	"BINDING 15,16-dihydrobiliverdin (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"DBV" EXACT RESID-alternate []
xref	DiffAvg: "584.67"
xref	DiffFormula: "C 33 H 36 N 4 O 6 S 0"
xref	DiffMono: "584.263485"
xref	Formula: "C 39 H 46 N 6 O 8 S 2"
xref	MassAvg: "790.95"
xref	MassMono: "790.281854"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1144. MOD:01144 S-(sn-1-2,3-dipalmitoylglycerol)-L-cysteine

Table 1146. Term [MOD:01144]
id	MOD:01144
name	S-(sn-1-2,3-dipalmitoylglycerol)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(sn-1-2,3-dipalmitoyl-glycerol)cysteine." [DeltaMass:0, PubMed:10896212, PubMed:4575979, PubMed:9056182, RESID:AA0107#var]
comment	From DeltaMass: Average Mass: 524
subset	PSI-MOD-slim
synonym	"S-(sn-1-Dipalmitoyl-glyceryl)- (on Cysteine)" EXACT DeltaMass-label []
xref	DiffAvg: "550.91"
xref	DiffFormula: "C 35 H 66 N 0 O 4 S 0"
xref	DiffMono: "550.496111"
xref	Formula: "C 38 H 71 N 1 O 5 S 1"
xref	MassAvg: "654.05"
xref	MassMono: "653.505295"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00116 S-diacylglycerol-L-cysteine ! S-diacylglycerol-L-cysteine

2.1145. MOD:01145 N-tau-(ADP-ribosyl)diphthamide

Table 1147. Term [MOD:01145]
id	MOD:01145
name	N-tau-(ADP-ribosyl)diphthamide
def	"A protein modification that effectively converts an L-histidine residue to N-tau-(ADP-ribosyl)diphthamide." [DeltaMass:0]
comment	From DeltaMass: (name misspelled "N theta -(ADP-ribosyl) diphthamide (of Histidine)") Average Mass: 648
xref	DiffAvg: "684.51"
xref	DiffFormula: "C 22 H 36 N 7 O 14 P 2"
xref	DiffMono: "684.178999"
xref	FormalCharge: "1+"
xref	Formula: "C 28 H 43 N 10 O 15 P 2"
xref	MassAvg: "821.65"
xref	MassMono: "821.237910"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
relationship	derives_from MOD:00049 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine ! 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine

2.1146. MOD:01146 S-(6-FAD)-L-cysteine

Table 1148. Term [MOD:01146]
id	MOD:01146
name	S-(6-FAD)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(6-FAD)-L-cystine." [DeltaMass:0]
comment	From DeltaMass: Average Mass: 784 with no citation. This modification has not been reported [JSG].
subset	PSI-MOD-slim
synonym	"FAD" RELATED PSI-MS-label []
synonym	"S6FADCys" EXACT PSI-MOD-label []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2 S 0"
xref	DiffMono: "783.141485"
xref	Formula: "C 30 H 36 N 10 O 16 P 2 S 1"
xref	MassAvg: "886.68"
xref	MassMono: "886.150669"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1147. MOD:01147 (Hex)3-HexNAc-(dHex)HexNAc

Table 1149. Term [MOD:01147]
id	MOD:01147
name	(Hex)3-HexNAc-(dHex)HexNAc
def	"modification from DeltaMass" [DeltaMass:0]
comment	From DeltaMass: Average Mass: 1,039
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00947 DeltaMass ! DeltaMass

2.1148. MOD:01148 ubiquitinylated lysine

Table 1150. Term [MOD:01148]
id	MOD:01148
name	ubiquitinylated lysine
def	"A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin." [PubMed:11125103, PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
relationship	contains MOD:00134 N6-glycyl-L-lysine ! N6-glycyl-L-lysine

2.1149. MOD:01149 sumoylated lysine

Table 1151. Term [MOD:01149]
id	MOD:01149
name	sumoylated lysine
def	"A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein." [PubMed:12612601, PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
relationship	contains MOD:00134 N6-glycyl-L-lysine ! N6-glycyl-L-lysine

2.1150. MOD:01150 neddylated lysine

Table 1152. Term [MOD:01150]
id	MOD:01150
name	neddylated lysine
def	"A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein." [PubMed:11125103, PubMed:12612601, PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
relationship	contains MOD:00134 N6-glycyl-L-lysine ! N6-glycyl-L-lysine

2.1151. MOD:01151 phosphorylated residue with neutral loss of phosphate

Table 1153. Term [MOD:01151]
id	MOD:01151
name	phosphorylated residue with neutral loss of phosphate
def	"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid phosphorylated residue with a secondary loss of a neutral trihydrogen phosphate molecular fragment." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "-97.99"
xref	DiffFormula: "C 0 H -3 N 0 O -4 P -1"
xref	DiffMono: "-97.976895"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00432 modified residue with neutral loss of phosphate ! modified residue with neutral loss of phosphate

2.1152. MOD:01152 carboxylated residue

Table 1154. Term [MOD:01152]
id	MOD:01152
name	carboxylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a carboxylic acid group." [UniMod:299]
subset	PSI-MOD-slim
synonym	"Carboxy" RELATED UniMod-interim []
synonym	"Carboxylation" RELATED UniMod-description []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1153. MOD:01153 methylthiolated residue

Table 1155. Term [MOD:01153]
id	MOD:01153
name	methylthiolated residue
def	"A protein modification that effectively replaces a hydrogen atom with an methylsulfanyl group (thiomethyl group)." [UniMod:39]
subset	PSI-MOD-slim
synonym	"Beta-methylthiolation" RELATED UniMod-description []
synonym	"Methylthio" RELATED UniMod-interim []
xref	DiffAvg: "46.09"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 1"
xref	DiffMono: "45.987721"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01886 thiolated residue ! thiolated residue

2.1154. MOD:01154 pyruvic acid

Table 1156. Term [MOD:01154]
id	MOD:01154
name	pyruvic acid
def	"A protein modification that effectively converts a source amino acid to pyruvic acid." [PubMed:10085076, PubMed:3042771, PubMed:8464063, RESID:AA0127]
subset	PSI-MOD-slim
synonym	"2-oxopropanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES Pyruvic acid (Cys)" EXACT UniProt-feature []
synonym	"MOD_RES Pyruvic acid (Ser)" EXACT UniProt-feature []
synonym	"pyruvic acid" EXACT RESID-name []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 3 O 2"
xref	MassAvg: "71.06"
xref	MassMono: "71.013304"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "N-term"
is_a	MOD:00769 residues isobaric at 71.0-71.1 Da ! residues isobaric at 71.0-71.1 Da
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1155. MOD:01155 lipoconjugated residue

Table 1157. Term [MOD:01155]
id	MOD:01155
name	lipoconjugated residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a lipid-like group either through acylation, alkylation, or amidation." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1156. MOD:01156 protein modification categorized by chemical process

Table 1158. Term [MOD:01156]
id	MOD:01156
name	protein modification categorized by chemical process
def	"Modified amino acid residue derived from a natural amino acid by a real or hypothetical chemical process." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	[MOD:00000] ! protein modification

2.1157. MOD:01157 protein modification categorized by amino acid modified

Table 1159. Term [MOD:01157]
id	MOD:01157
name	protein modification categorized by amino acid modified
def	"A protein modification considered either as modified amino acid residues derived from natural amino acids, as a replacement by another natural amino acid, or as a replacement by an unnatural amino acid." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	[MOD:00000] ! protein modification

2.1158. MOD:01158 modified L-selenocysteine residue

Table 1160. Term [MOD:01158]
id	MOD:01158
name	modified L-selenocysteine residue
def	"A protein modification that modifies an L-selenocysteine residue." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "U"
is_a	MOD:00745 selenium containing residue ! selenium containing residue
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified
relationship	derives_from MOD:00031 L-selenocysteine residue ! L-selenocysteine residue

2.1159. MOD:01159 peptidoglycanated residue

Table 1161. Term [MOD:01159]
id	MOD:01159
name	peptidoglycanated residue
def	"A protein modification that effectively attaches a residue to murein peptidoglycan by either a pentaglycine linker peptide or a peptide-like L-alanyl-D-glutamyl-2,6-diaminopimelic acid linkage." [PubMed:18688235]
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue

2.1160. MOD:01160 deaminated residue

Table 1162. Term [MOD:01160]
id	MOD:01160
name	deaminated residue
def	"A protein modification that effectively results in the loss of an ammonia, usually by a process of vicinal dehydration, rearrangement, and rehydration with release of ammonia, resulting in a loss of nitrogen with no gain of oxygen." [UniMod:385]
subset	PSI-MOD-slim
synonym	"Ammonia-loss" RELATED UniMod-interim []
synonym	"Loss of ammonia" RELATED UniMod-description []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1161. MOD:01161 deoxygenated residue

Table 1163. Term [MOD:01161]
id	MOD:01161
name	deoxygenated residue
def	"A protein modification that effectively removes oxygen atoms from a residue without the removal of hydrogen atoms." [PubMed:14235557, UniMod:447]
subset	PSI-MOD-slim
synonym	"Deoxy" RELATED PSI-MS-label []
synonym	"dOxyRes" EXACT PSI-MOD-label []
synonym	"reduction" RELATED UniMod-description []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "C 0 H 0 N 0 O -1"
xref	DiffMono: "-15.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01472 reduced residue ! reduced residue

2.1162. MOD:01162 fucosylated biantennary

Table 1164. Term [MOD:01162]
id	MOD:01162
name	fucosylated biantennary
def	"modification from UniMod N-linked glycosylation" [UniMod:308]
synonym	"dHex(1)Hex(5)HexNAc(4)" RELATED PSI-MS-label []
synonym	"Fucosylated biantennary" RELATED UniMod-description []
xref	DiffAvg: "1769.62"
xref	DiffFormula: "C 68 H 112 N 4 O 49"
xref	DiffMono: "1768.639516"
xref	Formula: "C 72 H 118 N 6 O 51"
xref	MassAvg: "1883.73"
xref	MassMono: "1882.682443"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00725 complex glycosylation ! complex glycosylation

2.1163. MOD:01163 guanylated residue

Table 1165. Term [MOD:01163]
id	MOD:01163
name	guanylated residue
def	"A protein modification that effectively crosslinks an amino acid residue and 5'-phosphoguanosine through either a phosphodiester or a phosphoramide bond." [DeltaMass:304, UniMod:413]
comment	From DeltaMass: (formula incorrect, N and O reversed) Average Mass: 345 Formula: C10H12O5N7P1 Monoisotopic Mass Change: 345.047 Average Mass Change: 345.209.
synonym	"5’phos Guanosyl" EXACT DeltaMass-label []
synonym	"phospho-guanosine" RELATED UniMod-description []
synonym	"Phosphoguanosine" RELATED PSI-MS-label []
xref	DiffAvg: "345.21"
xref	DiffFormula: "C 10 H 12 N 5 O 7 P 1"
xref	DiffMono: "345.047434"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.1164. MOD:01164 riboflavin-phosphoryl

Table 1166. Term [MOD:01164]
id	MOD:01164
name	riboflavin-phosphoryl
def	"A protein modification that effectively results from forming an adduct with a compound containing a riboflavin phosphate (flavin mononucleotide, FMN) group through a phosphodiester bond." [UniMod:442]
subset	PSI-MOD-slim
synonym	"FMN" RELATED PSI-MS-label []
synonym	"O3-(riboflavin phosphoryl)" RELATED UniMod-description []
xref	DiffAvg: "438.33"
xref	DiffFormula: "C 17 H 19 N 4 O 8 P 1"
xref	DiffMono: "438.094050"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue

2.1165. MOD:01165 adenylated residue

Table 1167. Term [MOD:01165]
id	MOD:01165
name	adenylated residue
def	"A protein modification that effectively crosslinks an amino acid residue and 5'-phosphoadenosine through either a phosphodiester or a phosphoramide bond." [DeltaMass:0, UniMod:405]
comment	From DeltaMass: (name misspelled "5’phos adenosinyl") Average Mass: 329
subset	PSI-MOD-slim
synonym	"5’phos Adenosinyl" EXACT DeltaMass-label []
synonym	"AMP binding site" RELATED UniMod-description []
synonym	"Phosphoadenosine" RELATED PSI-MS-label []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.1166. MOD:01166 uridylated residue

Table 1168. Term [MOD:01166]
id	MOD:01166
name	uridylated residue
def	"A protein modification that effectively crosslinks an amino acid residue and 5'-phosphouridine through either a phosphodiester or a phosphoramide bond." [DeltaMass:292, UniMod:417]
comment	From DeltaMass: (name misspelled "5’phos Uridinyl" and formula incorrect, N and O reversed) Average Mass: 306 Formula: C9H11O2N8P1 Monoisotopic Mass Change: 306.025 Average Mass Change: 306.17
synonym	"5’phos Uridinyl" EXACT DeltaMass-label []
synonym	"PhosphoUridine" RELATED PSI-MS-label []
synonym	"uridine phosphodiester" RELATED UniMod-description []
xref	DiffAvg: "306.17"
xref	DiffFormula: "C 9 H 11 N 2 O 8 P 1"
xref	DiffMono: "306.025302"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00701 nucleotide or nucleic acid modified residue ! nucleotide or nucleic acid modified residue

2.1167. MOD:01167 molybdopterin guanine dinucleotide

Table 1169. Term [MOD:01167]
id	MOD:01167
name	molybdopterin guanine dinucleotide
def	"modification from UniMod" [UniMod:424]
synonym	"molybdenum bis(molybdopterin guanine dinucleotide)" RELATED UniMod-description []
synonym	"MolybdopterinGD" RELATED PSI-MS-label []
xref	DiffAvg: "1572.02"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 26 P 4 S 4"
xref	DiffMono: "1572.985775"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification

2.1168. MOD:01168 dehydroalanine

Table 1170. Term [MOD:01168]
id	MOD:01168
name	dehydroalanine
def	"A protein modification that effectively converts a source amino acid residue to dehydroalanine." [PubMed:10220322, PubMed:1547888, PubMed:1815586, PubMed:2914619, PubMed:6838602, PubMed:7947813, PubMed:8239649, RESID:AA0181]
subset	PSI-MOD-slim
synonym	"2,3-didehydroalanine" EXACT RESID-alternate []
synonym	"2-aminoacrylic acid" EXACT RESID-alternate []
synonym	"2-aminopropenoic acid" EXACT RESID-systematic []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"anhydroserine" EXACT RESID-alternate []
synonym	"dehydroalanine" EXACT RESID-name []
synonym	"Dha" EXACT RESID-alternate []
synonym	"dHAla" EXACT PSI-MOD-label []
synonym	"MOD_RES 2,3-didehydroalanine (Cys)" EXACT UniProt-feature []
synonym	"MOD_RES 2,3-didehydroalanine (Ser)" EXACT UniProt-feature []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1169. MOD:01169 L-3-oxoalanine

Table 1171. Term [MOD:01169]
id	MOD:01169
name	L-3-oxoalanine
def	"A protein modification that effectively converts a source amino acid residue to L-oxoalanine." [DeltaMass:349, PubMed:14563551, PubMed:7628016, PubMed:8681943, PubMed:9478923, RESID:AA0185]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-oxopropanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-oxopropionic acid" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine" RELATED RESID-misnomer []
synonym	"L-3-oxoalanine" EXACT RESID-name []
synonym	"L-amino-malonic acid semialdehyde" EXACT RESID-alternate []
synonym	"L-aminomalonaldehydic acid" EXACT RESID-alternate []
synonym	"L-serinesemialdehyde" RELATED RESID-misnomer []
synonym	"MOD_RES 3-oxoalanine (Cys)" EXACT UniProt-feature []
synonym	"MOD_RES 3-oxoalanine (Ser)" EXACT UniProt-feature []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 3 N 1 O 2"
xref	MassAvg: "85.06"
xref	MassMono: "85.016378"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1170. MOD:01170 pyruvic acid iminylated residue

Table 1172. Term [MOD:01170]
id	MOD:01170
name	pyruvic acid iminylated residue
def	"A protein modification that effectively forms a 2-ketoimine of pyruvicacid with a residue amino group." [UniMod:422]
synonym	"N-pyruvic acid 2-iminyl" RELATED UniMod-description []
synonym	"PyruvicAcidIminyl" RELATED PSI-MS-label []
xref	DiffAvg: "70.05"
xref	DiffFormula: "C 3 H 2 N 0 O 2"
xref	DiffMono: "70.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "N-term"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1171. MOD:01171 O-acetyl-L-threonine

Table 1173. Term [MOD:01171]
id	MOD:01171
name	O-acetyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-acetyl-L-threonine." [PubMed:16728640, RESID:AA0423, UniMod:1#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-3-(acetyloxy)-2-aminobutanoic acid" EXACT RESID-systematic []
synonym	"Acetylation" RELATED UniMod-description []
synonym	"ACT_SITE O-acetylthreonine intermediate" EXACT UniProt-feature []
synonym	"MOD_RES O-acetylthreonine" EXACT UniProt-feature []
synonym	"O-acetyl-L-threonine" EXACT RESID-name []
synonym	"O-acetylthreonine" EXACT RESID-alternate []
synonym	"OAcThr" EXACT PSI-MOD-label []
synonym	"threonine acetate ester" EXACT RESID-alternate []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "C 6 H 9 N 1 O 3"
xref	MassAvg: "143.14"
xref	MassMono: "143.058243"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00644 O-acetylated residue ! O-acetylated residue
is_a	MOD:01186 acetylated L-threonine ! acetylated L-threonine

2.1172. MOD:01172 N-alanyl-glycosylsphingolipidinositolethanolamine

Table 1174. Term [MOD:01172]
id	MOD:01172
name	N-alanyl-glycosylsphingolipidinositolethanolamine
def	"A protein modification that effectively converts an L-alanine residue to N-alanyl-glycosylsphingolipidinositolethanolamine." [PubMed:12626404, RESID:AA0424]
synonym	"GSIAla" EXACT PSI-MOD-label []
synonym	"LIPID GPI-like-anchor amidated alanine" EXACT UniProt-feature []
synonym	"N-alanyl-glycosylsphingolipidinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 12 N 2 O 5 P 1"
xref	MassAvg: "211.13"
xref	MassMono: "211.048383"
xref	Origin: "A"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00466 glycosylsphingolipidinositolated residue ! glycosylsphingolipidinositolated residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.1173. MOD:01173 N-asparaginyl-glycosylsphingolipidinositolethanolamine

Table 1175. Term [MOD:01173]
id	MOD:01173
name	N-asparaginyl-glycosylsphingolipidinositolethanolamine
def	"A protein modification that effectively converts an L-asparagine residue to N-asparaginyl-glycosylsphingolipidinositolethanolamine." [PubMed:12626404, RESID:AA0425]
synonym	"GSIAsn" EXACT PSI-MOD-label []
synonym	"LIPID GPI-like-anchor amidated asparagine" EXACT UniProt-feature []
synonym	"N-asparaginyl-glycosylsphingolipidinositolethanolamine" EXACT RESID-name []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 6 H 13 N 3 O 6 P 1"
xref	MassAvg: "254.16"
xref	MassMono: "254.054197"
xref	Origin: "N"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00466 glycosylsphingolipidinositolated residue ! glycosylsphingolipidinositolated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.1174. MOD:01174 S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)-L-cysteine

Table 1176. Term [MOD:01174]
id	MOD:01174
name	S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)-L-cysteine." [ChEBI:27485, PubMed:11466314, PubMed:12684535, RESID:AA0426]
synonym	"(2R)-2-amino-3-([(5Z,9Xi,12E,14Z)-1-hydroxy-1,11-oxoprosta-5,12,14-trien-9-yl]sulfanyl)propanoic acid" EXACT RESID-alternate []
synonym	"(5Z,9Xi,12E,14Z)-9-([(2R)-2-amino-3-carboxyethyl]sulfanyl)-11-oxoprosta-5,12,14-trien-1-oic acid" EXACT RESID-systematic []
synonym	"LIPID S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)cysteine" EXACT UniProt-feature []
synonym	"PG-J2Cys" EXACT PSI-MOD-label []
synonym	"S-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "316.44"
xref	DiffFormula: "C 20 H 28 N 0 O 3 S 0"
xref	DiffMono: "316.203845"
xref	Formula: "C 23 H 33 N 1 O 4 S 1"
xref	MassAvg: "419.58"
xref	MassMono: "419.213030"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue

2.1175. MOD:01175 S-phycourobilin-L-cysteine

Table 1177. Term [MOD:01175]
id	MOD:01175
name	S-phycourobilin-L-cysteine
def	"A protein modification that effectively results from forming an adduct between a cysteine residue and the tetrapyrrole compound phycourobilin." [PubMed:1903388, PubMed:3208761, PubMed:3838747, RESID:AA0427]
synonym	"(2S,3R,16R)-18-ethenyl-3-[(1R)-1-([®-2-amino-2-carboxyethyl]sulfanyl)ethyl]-8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-4,5,15,16-tetrahydrobiline-1,19(21H,22H,24H)-dione" EXACT RESID-systematic []
synonym	"18-ethenyl-3-[1-(2-amino-2-carboxyethylsulfanyl)ethyl]-2,3,15,16-dihydro-2,7,13,17-tetramethyl-1,19-dioxo-(21H,22H,24H)-bilin-8,12-dipropanoic acid" EXACT RESID-alternate []
synonym	"BINDING Phycourobilin chromophore (covalent; via 1 link)" EXACT UniProt-feature []
synonym	"phycourobilin cysteine adduct" EXACT RESID-alternate []
synonym	"PUB" EXACT RESID-alternate []
synonym	"PUBCys" EXACT PSI-MOD-label []
synonym	"S-phycourobilin-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "586.69"
xref	DiffFormula: "C 33 H 38 N 4 O 6 S 0"
xref	DiffMono: "586.279135"
xref	Formula: "C 36 H 43 N 5 O 7 S 1"
xref	MassAvg: "689.83"
xref	MassMono: "689.288320"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00700 tetrapyrrole modified residue ! tetrapyrrole modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1176. MOD:01176 L-dehydrolysinonorleucine

Table 1178. Term [MOD:01176]
id	MOD:01176
name	L-dehydrolysinonorleucine
def	"A protein modification that effectively cross-links an L-lysine residue and an L-lysine residue converted to allysine with a carbon-nitrogen bond to form L-dehydrolysinonorleucine." [PubMed:16929109, RESID:AA0430]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(5S)-5-amino-5-carboxypentylidene]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"6-(N6-L-didehydrolysino)-L-norleucine" EXACT RESID-alternate []
synonym	"CROSSLNK Dehydrolysinonorleucine (Lys-Lys)" EXACT UniProt-feature []
synonym	"dehydrolysinorleucine [misspelling]" EXACT RESID-alternate []
synonym	"dehydrolysylnorleucine" EXACT RESID-alternate []
synonym	"didehydrolysinonorleucine" EXACT RESID-alternate []
synonym	"L-dehydrolysinonorleucine" EXACT RESID-name []
synonym	"N6-[(5S)-5-amino-5-carboxypentylidene]-L-lysine" EXACT RESID-alternate []
synonym	"XLNK6NleN6Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "-19.05"
xref	DiffFormula: "C 0 H -5 N -1 O 0"
xref	DiffMono: "-19.042199"
xref	Formula: "C 12 H 19 N 3 O 2"
xref	MassAvg: "237.30"
xref	MassMono: "237.147727"
xref	Origin: "K, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1177. MOD:01177 1'-(1,2,3-trihydroxyprop-2-yl)-L-histidine

Table 1179. Term [MOD:01177]
id	MOD:01177
name	1'-(1,2,3-trihydroxyprop-2-yl)-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 1'-(1,2,3-trihydroxyprop-2-yl)-L-histidine." [PubMed:16760471, RESID:AA0431]
synonym	"(S)-2-amino-3-[1-(1,2,3-trihydroxypropan-2-yl)-1H-imidazol-4-yl]propanoic acid" EXACT RESID-systematic []
synonym	"1'-(1,2,3-trihydroxyprop-2-yl)-L-histidine" EXACT RESID-name []
synonym	"1-[1,2-dihydroxy-1-(hydroxymethyl)ethyl]-L-histidine" EXACT RESID-alternate []
synonym	"MOD_RES Tele-(1,2,3-trihydroxypropan-2-yl)histidine" EXACT UniProt-feature []
synonym	"N(epsilon)-histidine dihydroxyacetone adduct" EXACT RESID-alternate []
synonym	"N(tau)-(1,2,3-trihydroxypropan-2-yl)histidine" EXACT RESID-alternate []
synonym	"NtauDHAHis" EXACT PSI-MOD-label []
synonym	"tele-(1,2,3-trihydroxypropan-2-yl)histidine" EXACT RESID-alternate []
xref	DiffAvg: "90.08"
xref	DiffFormula: "C 3 H 6 N 0 O 3"
xref	DiffMono: "90.031694"
xref	Formula: "C 9 H 13 N 3 O 4"
xref	MassAvg: "227.22"
xref	MassMono: "227.090606"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1178. MOD:01178 S-(aspart-4-yloxy) thiocarbonate

Table 1180. Term [MOD:01178]
id	MOD:01178
name	S-(aspart-4-yloxy) thiocarbonate
def	"A protein modification that effectively converts an L-aspartic acid residue to S-(aspart-4-yloxy) thiocarbonate." [PubMed:16627948, RESID:AA0432]
comment	This modification was originally observed in an Entamoeba histolytica enzyme expressed in Escherichia coli. It was not chemically confirmed or characterized. It did not appear in a later model at higher resolution by the same group. This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
synonym	"(2S)-2-amino-4-(carboxysulfanyl)oxy-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"4-aspartyloxysulfanylcarbonate" EXACT RESID-alternate []
synonym	"AspOSCO2H" EXACT PSI-MOD-label []
synonym	"O-carboxysulfanyl-4-oxo-L-homoserine" EXACT RESID-alternate []
synonym	"S-(aspart-4-yloxy) thiocarbonate" EXACT RESID-name []
xref	DiffAvg: "76.07"
xref	DiffFormula: "C 1 H 0 N 0 O 2 S 1"
xref	DiffMono: "75.961900"
xref	Formula: "C 5 H 5 N 1 O 5 S 1"
xref	MassAvg: "191.16"
xref	MassMono: "190.988843"
xref	Origin: "D"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1179. MOD:01179 N,N-dimethyl-L-alanine

Table 1181. Term [MOD:01179]
id	MOD:01179
name	N,N-dimethyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N,N-dimethyl-L-alanine." [PubMed:17691833, PubMed:387091, RESID:AA0433]
synonym	"(S)-1-carboxy-N,N-dimethylaminoethane" EXACT RESID-alternate []
synonym	"(S)-2-(dimethylamino)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N,N-dimethylalanine" EXACT UniProt-feature []
synonym	"N,N-dimethyl-L-alanine" EXACT RESID-name []
synonym	"N,N-dimethylalanine" EXACT RESID-alternate []
synonym	"NMe2Ala" EXACT PSI-MOD-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 5 H 10 N 1 O 1"
xref	MassAvg: "100.14"
xref	MassMono: "100.076239"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01461 N-methylated alanine ! N-methylated alanine
is_a	MOD:01686 alpha-amino dimethylated residue ! alpha-amino dimethylated residue

2.1180. MOD:01180 2-hydroxyglycine observational artifact

Table 1182. Term [MOD:01180]
id	MOD:01180
name	2-hydroxyglycine observational artifact
def	"A protein modification that effectively converts a glycine residue to 2-hydroxyglycine." [ChEBI:38048, PubMed:16178056, PubMed:17431180, PubMed:17823333, RESID:AA0434]
comment	CAUTION - peptides of 2-hydroxyglycine are known to be unstable, decaying to break the peptide backbone or to form peptidyl amides [see J. Am. Chem. Soc. 111, 1933-1934, 1989, and J. Org. Chem. 57, 3916-3921, 1992]. If computer analysis of tandem mass-spectrometric results predicts this modification, then it is most probable that there are multiple isobaric peptides differing in the location of multiple hydroxylation modifications [JSG].
synonym	"2-hydroxyglycine" EXACT RESID-name []
synonym	"2HyGly" EXACT PSI-MOD-label []
synonym	"alpha-hydroxyglycine" EXACT RESID-alternate []
synonym	"amino(hydroxy)acetic acid" EXACT RESID-systematic []
synonym	"aminohydroxyacetic acid" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 2 H 3 N 1 O 2"
xref	MassAvg: "73.05"
xref	MassMono: "73.016378"
xref	Origin: "G"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.1181. MOD:01181 L-aspartic acid 4-methyl ester

Table 1183. Term [MOD:01181]
id	MOD:01181
name	L-aspartic acid 4-methyl ester
def	"A protein modification that effectively converts an L-aspartic acid residue to L-aspartate 4-methyl ester." [OMSSA:69, PubMed:1556110, PubMed:16888766, PubMed:9629898, RESID:AA0435, UniMod:34#D]
comment	CAUTION - observations of this modifation are attributable to artifacts produced in preparation. It is extremely unlikely that eukaryotes produce this modification, because an enzyme acting to form the methyl ester of L-aspartyl peptides would interfere with the D-aspartyl peptide repair mechanism [JSG].
synonym	"(2S)-2-amino-4-methoxy-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-aminobutanedioic acid 4-methyl ester" EXACT RESID-alternate []
synonym	"4-methyl L-2-aminosuccinic acid" EXACT RESID-alternate []
synonym	"4-methyl L-aspartate" EXACT RESID-alternate []
synonym	"4-methyl L-hydrogen aspartate" EXACT RESID-alternate []
synonym	"aspartic acid 4-methyl ester" EXACT RESID-alternate []
synonym	"aspartic acid beta-methyl ester" EXACT RESID-alternate []
synonym	"L-aspartic acid 4-methyl ester" EXACT RESID-name []
synonym	"meesterd" EXACT OMSSA-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"O4MeAsp" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00393 O-methylated residue ! O-methylated residue
is_a	MOD:01681 monomethylated L-aspartic acid ! monomethylated L-aspartic acid

2.1182. MOD:01182 6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FAD

Table 1184. Term [MOD:01182]
id	MOD:01182
name	6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FAD
def	"A protein modification that crosslinks a cysteine and a histidine residue by forming the adduct 6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FAD." [PubMed:, RESID:AA0436]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"6-(®-2-amino-2-carboxyethyl)sulfanyl-8alpha-[4-((S)-2-amino-2-carboxyethyl)imidazol-3-yl]-riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine" EXACT RESID-systematic []
synonym	"6-(S-cysteinyl)-8alpha-(N(delta1)-histidyl)-FAD" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(N(pi)-histidyl)-FAD" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(N3'-histidyl)-FAD" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(pros-histidyl)-FAD" EXACT RESID-alternate []
synonym	"6-(S-L-cysteinyl)-8alpha-(N3'-L-histidino)-FAD" EXACT RESID-name []
synonym	"BINDING FAD (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"BINDING FAD (covalent; via 2 links, pros nitrogen)" EXACT UniProt-feature []
synonym	"SCys6-NprosHis8a-FAD" EXACT PSI-MOD-label []
xref	DiffAvg: "781.52"
xref	DiffFormula: "C 27 H 29 N 9 O 15 P 2 S 0"
xref	DiffMono: "781.125835"
xref	Formula: "C 36 H 41 N 13 O 17 P 2 S 1"
xref	MassAvg: "1021.81"
xref	MassMono: "1021.193931"
xref	Origin: "C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01621 flavin crosslinked residues ! flavin crosslinked residues

2.1183. MOD:01183 L-selenocystine (oxidized selenocysteine) (Sec-Sec)

Table 1185. Term [MOD:01183]
id	MOD:01183
name	L-selenocystine (oxidized selenocysteine) (Sec-Sec)
def	"A protein modification that effectively cross-links two L-selenocysteine residues to form L-selenocystine," [ChEBI:28553, PubMed:17715293, PubMed:6076213, RESID:AA0437]
comment	Cross-link 2; for formation of the same modification by substitution of 2 selenium for 2 sulfur atoms in L-cystine, see MOD:01184.
subset	PSI-MOD-slim
synonym	"(R,R)-3,3'-diselane-1,2-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"3,3'-diselenobis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-diselenobisalanine" EXACT RESID-alternate []
synonym	"3,3'-diselenodialanine" EXACT RESID-alternate []
synonym	"beta,beta'-diamino-beta,beta'-dicarboxydiethyldiselenide" EXACT RESID-alternate []
synonym	"beta,beta'-diselenodialanine" EXACT RESID-alternate []
synonym	"bis(alpha-aminopropionic acid)-beta-diselenide" EXACT RESID-alternate []
synonym	"bis(beta-amino-beta-carboxyethyl)diselenide" EXACT RESID-alternate []
synonym	"CROSSLNK Selenocystine (Sec-Sec)" EXACT UniProt-feature []
synonym	"diselenocysteine" EXACT RESID-alternate []
synonym	"L-selenocystine" EXACT RESID-name []
synonym	"Sec2" EXACT PSI-MOD-label []
synonym	"selenium cystine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 Se 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 2 Se 2"
xref	MassAvg: "298.08"
xref	MassMono: "299.891620"
xref	Origin: "U, U"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:01158 modified L-selenocysteine residue ! modified L-selenocysteine residue

2.1184. MOD:01184 L-selenocystine (selenium disubstituted L-cystine)

Table 1186. Term [MOD:01184]
id	MOD:01184
name	L-selenocystine (selenium disubstituted L-cystine)
def	"A protein modification that effectively substitutes two selenium atoms for two sulfur atoms in L-cystine to form L-selenocystine." [PubMed:17715293, RESID:AA0437#CYS2]
comment	Cross-link 2; for formation of the same modification by oxidation of two L-selenocysteine residues, see MOD:01183.
synonym	"(R,R)-3,3'-diselane-1,2-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"3,3'-diselenobis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-diselenobisalanine" EXACT RESID-alternate []
synonym	"3,3'-diselenodialanine" EXACT RESID-alternate []
synonym	"beta,beta'-diamino-beta,beta'-dicarboxydiethyldiselenide" EXACT RESID-alternate []
synonym	"beta,beta'-diselenodialanine" EXACT RESID-alternate []
synonym	"bis(alpha-aminopropionic acid)-beta-diselenide" EXACT RESID-alternate []
synonym	"bis(beta-amino-beta-carboxyethyl)diselenide" EXACT RESID-alternate []
synonym	"CROSSLNK Selenocystine (Sec-Sec)" EXACT UniProt-feature []
synonym	"diselenocysteine" EXACT RESID-alternate []
synonym	"L-selenocystine" EXACT RESID-name []
synonym	"Se2(S2)Cys2" EXACT PSI-MOD-label []
synonym	"selenium cystine" EXACT RESID-alternate []
xref	DiffAvg: "91.81"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S -2 Se 2"
xref	DiffMono: "93.873250"
xref	Formula: "C 6 H 8 N 2 O 2 Se 2"
xref	MassAvg: "298.08"
xref	MassMono: "299.891620"
xref	Origin: "C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00007 selenium substitution for sulfur ! selenium substitution for sulfur
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1185. MOD:01185 4-amidated L-aspartic acid

Table 1187. Term [MOD:01185]
id	MOD:01185
name	4-amidated L-aspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to L-asparagine." [PubMed:17962566, RESID:AA0003#ASP]
synonym	"(2S)-2-amino-4-butanediamic acid" EXACT RESID-systematic []
synonym	"2,4-bis(azanyl)-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"2,4-diamino-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"2-amino-3-carbamoylpropanoic acid" EXACT RESID-alternate []
synonym	"2-amino-4-butanediamic acid" EXACT RESID-alternate []
synonym	"2-aminosuccinamic acid" EXACT RESID-alternate []
synonym	"2-aminosuccinic acid 4-amide" EXACT RESID-alternate []
synonym	"4NAsp" EXACT PSI-MOD-label []
synonym	"alpha-amino-beta-carbamylpropionic acid" EXACT RESID-alternate []
synonym	"alpha-aminosuccinamic acid" EXACT RESID-alternate []
synonym	"aspartic acid 4-amide" EXACT RESID-alternate []
synonym	"aspartic acid beta-amide" EXACT RESID-alternate []
synonym	"beta-asparagine" EXACT RESID-alternate []
synonym	"L-asparagine" EXACT RESID-name []
synonym	"MOD_RES Amidated aspartic acid" EXACT UniProt-feature []
xref	DiffAvg: "-0.98"
xref	DiffFormula: "C 0 H 1 N 1 O -1"
xref	DiffMono: "-0.984016"
xref	Formula: "C 4 H 6 N 2 O 2"
xref	MassAvg: "114.10"
xref	MassMono: "114.042927"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00012 L-asparagine residue ! L-asparagine residue
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1186. MOD:01186 acetylated L-threonine

Table 1188. Term [MOD:01186]
id	MOD:01186
name	acetylated L-threonine
def	"A protein modification that effectively converts an L-threonine residue to either N-acetyl-L-threonne, or O-acetyl-Lthreonine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"AcThr" EXACT PSI-MOD-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "natural"
is_a	MOD:00394 acetylated residue ! acetylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1187. MOD:01187 L-pyrrolysine residue

Table 1189. Term [MOD:01187]
id	MOD:01187
name	L-pyrrolysine residue
def	"A protein modification that inserts or replaces a residue with an L-pyrrolysine residue, a natural pretranslational modification." [ChEBI:21860, PubMed:11435424, PubMed:12029131, PubMed:12029132, PubMed:15314242, PubMed:16096277, RESID:AA0321, UniMod:435]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-ylcarbonyl]aminohexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-ylcarbonyl]azanylhexanoic acid" EXACT RESID-alternate []
synonym	"L-pyrrolysine" EXACT RESID-name []
synonym	"monomethylamine methyltransferase cofactor lysine adduct" EXACT RESID-alternate []
synonym	"N6-(4-methyl-1,2-didehydropyrrolidine-5-carboxyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-(4-methyl-delta-1-pyrroline-5-carboxyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-([(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl)-L-lysine" EXACT RESID-alternate []
synonym	"NON_STD Pyrrolysine" EXACT UniProt-feature []
synonym	"Pyl" EXACT PSI-MOD-label []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 12 H 19 N 3 O 2"
xref	MassAvg: "237.30"
xref	MassMono: "237.147727"
xref	Origin: "O"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00868 natural, non-standard encoded residue ! natural, non-standard encoded residue

2.1188. MOD:01188 N-ethyl iodoacetamide-d5 - site Y

Table 1190. Term [MOD:01188]
id	MOD:01188
name	N-ethyl iodoacetamide-d5 - site Y
def	"modification from UniMod Isotopic label -" [PubMed:11710128, PubMed:12766232, PubMed:3155470, PubMed:957432, UniMod:212#Y]
synonym	"N-ethyl iodoacetamide-d5" RELATED UniMod-description []
synonym	"NEIAA:2H(5)" RELATED PSI-MS-label []
xref	DiffAvg: "90.08"
xref	DiffFormula: "C 4 (1)H 2 (2)H 5 N 1 O 1"
xref	DiffMono: "90.084148"
xref	Formula: "C 13 (1)H 11 (2)H 5 N 2 O 3"
xref	MassAvg: "253.15"
xref	MassMono: "253.147476"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00562 N-ethyl iodoacetamide-d5 ! N-ethyl iodoacetamide-d5

2.1189. MOD:01189 N-ethyl iodoacetamide-d5 - site C

Table 1191. Term [MOD:01189]
id	MOD:01189
name	N-ethyl iodoacetamide-d5 - site C
def	"modification from UniMod Isotopic label -" [PubMed:12766232, UniMod:212#C]
synonym	"N-ethyl iodoacetamide-d5" RELATED UniMod-description []
synonym	"NEIAA:2H(5)" RELATED PSI-MS-label []
xref	DiffAvg: "90.08"
xref	DiffFormula: "C 4 (1)H 2 (2)H 5 N 1 O 1"
xref	DiffMono: "90.084148"
xref	Formula: "C 7 (1)H 7 (2)H 5 N 2 O 2 S 1"
xref	MassAvg: "193.09"
xref	MassMono: "193.093332"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00562 N-ethyl iodoacetamide-d5 ! N-ethyl iodoacetamide-d5

2.1190. MOD:01190 dibromo

Table 1192. Term [MOD:01190]
id	MOD:01190
name	dibromo
def	"Modification from UniMod Chemical derivative. OBSOLETE because duplicate and redundant with MOD:01006. Remap to MOD:01006." [UniMod:534]
synonym	"Dibromo" RELATED PSI-MS-label []
synonym	"Dibromo" RELATED UniMod-description []
xref	DiffAvg: "157.79"
xref	DiffFormula: "Br 2 H -2"
xref	DiffMono: "155.821024"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Y"
xref	Source: "none"
xref	TermSpec: "none"
is_obsolete	true

2.1191. MOD:01191 N-ethyl iodoacetamide-d0 - site C

Table 1193. Term [MOD:01191]
id	MOD:01191
name	N-ethyl iodoacetamide-d0 - site C
def	"modification from UniMod Isotopic label -" [PubMed:12766232, UniMod:211#C]
synonym	"N-ethyl iodoacetamide-d0" RELATED UniMod-description []
synonym	"NEIAA" RELATED PSI-MS-label []
xref	DiffAvg: "85.11"
xref	DiffFormula: "C 4 H 7 N 1 O 1"
xref	DiffMono: "85.052764"
xref	Formula: "C 7 H 12 N 2 O 2 S 1"
xref	MassAvg: "188.25"
xref	MassMono: "188.061949"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00561 N-ethyl iodoacetamide-d0 ! N-ethyl iodoacetamide-d0

2.1192. MOD:01192 N-ethyl iodoacetamide-d0 - site Y

Table 1194. Term [MOD:01192]
id	MOD:01192
name	N-ethyl iodoacetamide-d0 - site Y
def	"modification from UniMod Isotopic label -" [PubMed:11760118, PubMed:12766232, UniMod:211#Y]
synonym	"N-ethyl iodoacetamide-d0" RELATED UniMod-description []
synonym	"NEIAA" RELATED PSI-MS-label []
xref	DiffAvg: "85.11"
xref	DiffFormula: "C 4 H 7 N 1 O 1"
xref	DiffMono: "85.052764"
xref	Formula: "C 13 H 16 N 2 O 3"
xref	MassAvg: "248.28"
xref	MassMono: "248.116092"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00561 N-ethyl iodoacetamide-d0 ! N-ethyl iodoacetamide-d0

2.1193. MOD:01193 phosphorylation to pyridyl thiol - site T

Table 1195. Term [MOD:01193]
id	MOD:01193
name	phosphorylation to pyridyl thiol - site T
def	"modification from UniMod Chemical derivative -" [PubMed:1093385, UniMod:264#T]
synonym	"PET" RELATED PSI-MS-label []
synonym	"phosphorylation to pyridyl thiol" RELATED UniMod-description []
xref	DiffAvg: "121.20"
xref	DiffFormula: "C 7 H 7 N 1 O -1 S 1"
xref	DiffMono: "121.035006"
xref	Formula: "C 11 H 14 N 2 O 1 S 1"
xref	MassAvg: "222.31"
xref	MassMono: "222.082684"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00586 phosphorylation to pyridyl thiol ! phosphorylation to pyridyl thiol

2.1194. MOD:01194 phosphorylation to pyridyl thiol - site S

Table 1196. Term [MOD:01194]
id	MOD:01194
name	phosphorylation to pyridyl thiol - site S
def	"modification from UniMod Chemical derivative -" [PubMed:15279557, UniMod:264#S]
synonym	"PET" RELATED PSI-MS-label []
synonym	"phosphorylation to pyridyl thiol" RELATED UniMod-description []
xref	DiffAvg: "121.20"
xref	DiffFormula: "C 7 H 7 N 1 O -1 S 1"
xref	DiffMono: "121.035006"
xref	Formula: "C 10 H 12 N 2 O 1 S 1"
xref	MassAvg: "208.28"
xref	MassMono: "208.067034"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00586 phosphorylation to pyridyl thiol ! phosphorylation to pyridyl thiol

2.1195. MOD:01195 benzoyl labeling reagent light form - site K

Table 1197. Term [MOD:01195]
id	MOD:01195
name	benzoyl labeling reagent light form - site K
def	"modification from UniMod Isotopic label -" [PubMed:11813307, PubMed:12777388, PubMed:15456300, UniMod:136#K]
synonym	"Benzoyl" RELATED PSI-MS-label []
synonym	"labeling reagent light form (N-term & K)" RELATED UniMod-description []
xref	DiffAvg: "104.11"
xref	DiffFormula: "C 7 H 4 O 1"
xref	DiffMono: "104.026215"
xref	Formula: "C 13 H 16 N 2 O 2"
xref	MassAvg: "232.28"
xref	MassMono: "232.121178"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00505 benzoyl labeling reagent light form (N-term and K) ! benzoyl labeling reagent light form (N-term and K)

2.1196. MOD:01196 5-dimethylaminonaphthalene-1-sulfonyl - site K

Table 1198. Term [MOD:01196]
id	MOD:01196
name	5-dimethylaminonaphthalene-1-sulfonyl - site K
def	"OBSOLETE because redundant, replaced with MOD:01654. Remap to MOD:01654." [UniMod:139]
synonym	"5-dimethylaminonaphthalene-1-sulfonyl" RELATED UniMod-description []
synonym	"Dansyl" RELATED PSI-MS-label []
xref	DiffAvg: "233.29"
xref	DiffFormula: "C 12 H 11 N 1 O 2 S 1"
xref	DiffMono: "233.051050"
xref	Formula: "C 18 H 23 N 3 O 3 S 1"
xref	MassAvg: "361.46"
xref	MassMono: "361.146013"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1197. MOD:01197 N-heptosyl-L-glutamine

Table 1199. Term [MOD:01197]
id	MOD:01197
name	N-heptosyl-L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to N-heptosyl-L-glutamine." [UniMod:490#Q]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 12 H 20 N 2 O 8"
xref	MassAvg: "320.30"
xref	MassMono: "320.121966"
xref	Origin: "Q"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1198. MOD:01198 O-heptosyl-L-serine

Table 1200. Term [MOD:01198]
id	MOD:01198
name	O-heptosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-heptosyl-L-serine." [UniMod:490#S]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 10 H 17 N 1 O 8"
xref	MassAvg: "279.25"
xref	MassMono: "279.095417"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1199. MOD:01199 N-heptosyl-L-arginine

Table 1201. Term [MOD:01199]
id	MOD:01199
name	N-heptosyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to an N-heptosyl-L-arginine." [UniMod:490#R]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 13 H 24 N 4 O 7"
xref	MassAvg: "348.36"
xref	MassMono: "348.164499"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1200. MOD:01200 O-heptosyl-L-threonine

Table 1202. Term [MOD:01200]
id	MOD:01200
name	O-heptosyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-heptosyl-L-threonine." [UniMod:490#T]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 11 H 19 N 1 O 8"
xref	MassAvg: "293.27"
xref	MassMono: "293.111067"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1201. MOD:01201 N6-heptosyl-L-lysine

Table 1203. Term [MOD:01201]
id	MOD:01201
name	N6-heptosyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-heptosyl-L-lysine." [UniMod:490#K]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 13 H 24 N 2 O 7"
xref	MassAvg: "320.34"
xref	MassMono: "320.158351"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1202. MOD:01202 N-heptosyl-L-asparagine

Table 1204. Term [MOD:01202]
id	MOD:01202
name	N-heptosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N-heptosyl-L-asparagine." [UniMod:490#N]
comment	From UniMod with no citation [JSG].
synonym	"Hep" RELATED PSI-MS-label []
synonym	"Heptose" RELATED UniMod-description []
xref	DiffAvg: "192.17"
xref	DiffFormula: "C 7 H 12 O 6"
xref	DiffMono: "192.063388"
xref	Formula: "C 11 H 18 N 2 O 8"
xref	MassAvg: "306.27"
xref	MassMono: "306.106316"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00925 heptosylated residue ! heptosylated residue

2.1203. MOD:01203 N6-(pyridylacetyl)lysine

Table 1205. Term [MOD:01203]
id	MOD:01203
name	N6-(pyridylacetyl)lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-[(pyrid-3-yl)acetyl]lysine." [PubMed:9276974, UniMod:25#K]
comment	Produced by reaction with N-[(pyrid-3-yl)acetyl]oxy-succinimide [JSG].
synonym	"Pyridylacetyl" RELATED PSI-MS-label []
synonym	"pyridylacetyl" RELATED UniMod-description []
xref	DiffAvg: "119.12"
xref	DiffFormula: "C 7 H 5 N 1 O 1"
xref	DiffMono: "119.037114"
xref	Formula: "C 13 H 17 N 3 O 2"
xref	MassAvg: "247.30"
xref	MassMono: "247.132077"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00418 pyridylacetylated residue ! pyridylacetylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1204. MOD:01204 prompt loss of methanethiol from oxidixed methionine

Table 1206. Term [MOD:01204]
id	MOD:01204
name	prompt loss of methanethiol from oxidixed methionine
def	"modification from UniMod Artifact -" [PubMed:9004526, UniMod:526]
synonym	"Dethiomethyl" RELATED PSI-MS-label []
synonym	"Prompt loss of side chain from oxidised Met" RELATED UniMod-description []
xref	DiffAvg: "-48.10"
xref	DiffFormula: "C -1 H -4 S -1"
xref	DiffMono: "-48.003371"
xref	Formula: "C 4 H 5 N 1 O 1 S 0"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.1205. MOD:01205 Hex1HexNAc1NeuAc2 O-glycosylated serine

Table 1207. Term [MOD:01205]
id	MOD:01205
name	Hex1HexNAc1NeuAc2 O-glycosylated serine
def	"A protein modification that effectively replaces an O3 hydrogen atom of a serine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc2 linked through a glycosidic bond." [PubMed:7949339, UniMod:160#S]
synonym	"Hex(1)HexNAc(1)NeuAc(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc2" RELATED UniMod-description []
xref	DiffAvg: "947.85"
xref	DiffFormula: "C 36 H 57 N 3 O 26"
xref	DiffMono: "947.323029"
xref	Formula: "C 39 H 62 N 4 O 28"
xref	MassAvg: "1034.93"
xref	MassMono: "1034.355057"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00528 Hex1HexNAc1NeuAc2 glycosylated residue ! Hex1HexNAc1NeuAc2 glycosylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1206. MOD:01206 Hex1HexNAc1NeuAc2 O-glycosylated threonine

Table 1208. Term [MOD:01206]
id	MOD:01206
name	Hex1HexNAc1NeuAc2 O-glycosylated threonine
def	"A protein modification that effectively replaces an O3 hydrogen atom of a threonine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc2 linked through a glycosidic bond." [UniMod:160#T]
synonym	"Hex(1)HexNAc(1)NeuAc(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc2" RELATED UniMod-description []
xref	DiffAvg: "947.85"
xref	DiffFormula: "C 36 H 57 N 3 O 26"
xref	DiffMono: "947.323029"
xref	Formula: "C 40 H 64 N 4 O 28"
xref	MassAvg: "1048.95"
xref	MassMono: "1048.370707"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00528 Hex1HexNAc1NeuAc2 glycosylated residue ! Hex1HexNAc1NeuAc2 glycosylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1207. MOD:01207 Hex1HexNAc1NeuAc2 N4-glycosylated asparagine

Table 1209. Term [MOD:01207]
id	MOD:01207
name	Hex1HexNAc1NeuAc2 N4-glycosylated asparagine
def	"A protein modification that effectively replaces an N4 hydrogen atom of an asparagine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc2 linked through a glycosidic bond." [UniMod:160#N]
synonym	"Hex(1)HexNAc(1)NeuAc(2)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc2" RELATED UniMod-description []
xref	DiffAvg: "947.85"
xref	DiffFormula: "C 36 H 57 N 3 O 26"
xref	DiffMono: "947.323029"
xref	Formula: "C 40 H 63 N 5 O 28"
xref	MassAvg: "1061.95"
xref	MassMono: "1061.365956"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00528 Hex1HexNAc1NeuAc2 glycosylated residue ! Hex1HexNAc1NeuAc2 glycosylated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.1208. MOD:01208 copper(1+) carboxylate C-terminal residue

Table 1210. Term [MOD:01208]
id	MOD:01208
name	copper(1+) carboxylate C-terminal residue
def	"A protein modification that effectively converts a C-terminal residue to the copper(1+) carboxylate salt." [UniMod:531#C-term]
synonym	"Cation:Cu[I]" RELATED PSI-MS-label []
synonym	"cuprous salt" EXACT PSI-MOD-alternate []
synonym	"Replacement of proton by copper" RELATED UniMod-description []
xref	DiffAvg: "62.54"
xref	DiffFormula: "Cu 1 H -1"
xref	DiffMono: "61.921772"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "C-term"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue

2.1209. MOD:01209 copper(1+) L-aspartate

Table 1211. Term [MOD:01209]
id	MOD:01209
name	copper(1+) L-aspartate
def	"A protein modification that effectively converts an L-aspartic acid residue to the copper(1+) aspartate salt." [UniMod:531#D]
synonym	"Cation:Cu[I]" RELATED PSI-MS-label []
synonym	"cuprous salt" EXACT PSI-MOD-alternate []
synonym	"Replacement of proton by copper" RELATED UniMod-description []
xref	DiffAvg: "62.54"
xref	DiffFormula: "Cu 1 H -1"
xref	DiffMono: "61.921772"
xref	Formula: "C 4 Cu 1 H 4 N 1 O 3"
xref	MassAvg: "177.63"
xref	MassMono: "176.948715"
xref	Origin: "D"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1210. MOD:01210 copper(1+) L-glutamate

Table 1212. Term [MOD:01210]
id	MOD:01210
name	copper(1+) L-glutamate
def	"A protein modification that effectively converts an L-glutamic acid residue to the copper(1+) glutamate salt." [UniMod:531#E]
synonym	"Cation:Cu[I]" RELATED PSI-MS-label []
synonym	"cuprous salt" EXACT PSI-MOD-alternate []
synonym	"Replacement of proton by copper" RELATED UniMod-description []
xref	DiffAvg: "62.54"
xref	DiffFormula: "Cu 1 H -1"
xref	DiffMono: "61.921772"
xref	Formula: "C 5 Cu 1 H 6 N 1 O 3"
xref	MassAvg: "191.65"
xref	MassMono: "190.964366"
xref	Origin: "E"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1211. MOD:01211 N6-(morpholine-2-acetyl)-lysine

Table 1213. Term [MOD:01211]
id	MOD:01211
name	N6-(morpholine-2-acetyl)-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-(morpholine-2-acetyl)-lysine." [PubMed:10446193, UniMod:29#K]
comment	The UniMod name "N-Succinimidyl-3-morpholine acetate" appears to have been a typographical error [JSG].
synonym	"N-Succinimidyl-2-morpholine acetate" RELATED UniMod-description []
synonym	"N-succinimidylmorpholine-2-acetate N6-derivatized lysine" EXACT PSI-MOD-alternate []
synonym	"SMA" RELATED PSI-MS-label []
xref	DiffAvg: "127.14"
xref	DiffFormula: "C 6 H 9 N 1 O 2"
xref	DiffMono: "127.063329"
xref	Formula: "C 12 H 21 N 3 O 3"
xref	MassAvg: "255.32"
xref	MassMono: "255.158292"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01813 morpholine-2-acetylated residue ! morpholine-2-acetylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1212. MOD:01212 iodoacetamide N6-derivatized lysine

Table 1214. Term [MOD:01212]
id	MOD:01212
name	iodoacetamide N6-derivatized lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-(carboxamidomethyl)lysine." [OMSSA:27, PubMed:11510821, PubMed:12422359, PubMed:12686488, UniMod:4#K]
subset	PSI-MOD-slim
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"carbamidomethylk" EXACT OMSSA-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
synonym	"N6-(2-amino-2-oxoethyl)lysine" EXACT PSI-MOD-alternate []
synonym	"N6-(carbamoylmethyl)lysine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "C 8 H 15 N 3 O 2"
xref	MassAvg: "185.23"
xref	MassMono: "185.116427"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1213. MOD:01213 iodoacetamide derivatized histidine

Table 1215. Term [MOD:01213]
id	MOD:01213
name	iodoacetamide derivatized histidine
def	"A protein modification that effectively converts an L-histidine residue to an iodoacetamide derivatized histidine, either 1'- or 3'-(carboxamidolmethyl)histidine." [OMSSA:28, PubMed:11510821, PubMed:12422359, PubMed:15627961, PubMed:2026710, UniMod:4#H]
subset	PSI-MOD-slim
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"carbamidometylh" EXACT OMSSA-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "C 8 H 10 N 4 O 2"
xref	MassAvg: "194.19"
xref	MassMono: "194.080376"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1214. MOD:01214 iodoacetamide - site C

Table 1216. Term [MOD:01214]
id	MOD:01214
name	iodoacetamide - site C
def	"modification from UniMod Chemical derivative - OBSOLETE because redundant, the difference component of MOD:01060. Remap to MOD:01060." [PubMed:10504701, PubMed:11510821, PubMed:12422359, UniMod:4#C]
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1215. MOD:01215 iodoacetamide derivatized aspartic acid

Table 1217. Term [MOD:01215]
id	MOD:01215
name	iodoacetamide derivatized aspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to O4-(carboxamidomethyl)aspartate." [OMSSA:29, PubMed:11510821, PubMed:12422359, PubMed:16526082, UniMod:4#D]
subset	PSI-MOD-slim
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"carbamidomethyld" EXACT OMSSA-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "C 6 H 8 N 2 O 4"
xref	MassAvg: "172.14"
xref	MassMono: "172.048407"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1216. MOD:01216 iodoacetamide derivatized glutamic acid

Table 1218. Term [MOD:01216]
id	MOD:01216
name	iodoacetamide derivatized glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to O5-(carboxamidomethyl)glutamate." [OMSSA:30, PubMed:11510821, PubMed:12422359, UniMod:4#E]
subset	PSI-MOD-slim
synonym	"Carbamidomethyl" RELATED PSI-MS-label []
synonym	"carbamidomethyle" EXACT OMSSA-label []
synonym	"Iodoacetamide derivative" RELATED UniMod-description []
xref	DiffAvg: "57.05"
xref	DiffFormula: "C 2 H 3 N 1 O 1"
xref	DiffMono: "57.021464"
xref	Formula: "C 7 H 10 N 2 O 4"
xref	MassAvg: "186.17"
xref	MassMono: "186.064057"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1217. MOD:01217 Sulfanilic Acid (SA), light C12 - site D

Table 1219. Term [MOD:01217]
id	MOD:01217
name	Sulfanilic Acid (SA), light C12 - site D
def	"modification from UniMod Isotopic label -" [PubMed:12872131, UniMod:285#D]
synonym	"Light Sulfanilic Acid (SA) C12" RELATED UniMod-description []
synonym	"SulfanilicAcid" RELATED PSI-MS-label []
xref	DiffAvg: "155.00"
xref	DiffFormula: "(12)C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "155.004099"
xref	Formula: "(12)C 10 H 10 N 2 O 5 S 1"
xref	MassAvg: "270.03"
xref	MassMono: "270.031042"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00605 Sulfanilic Acid (SA), light C12 ! Sulfanilic Acid (SA), light C12

2.1218. MOD:01218 Sulfanilic Acid (SA), light C12 - site E

Table 1220. Term [MOD:01218]
id	MOD:01218
name	Sulfanilic Acid (SA), light C12 - site E
def	"modification from UniMod Isotopic label -" [PubMed:15283597, UniMod:285#E]
synonym	"Light Sulfanilic Acid (SA) C12" RELATED UniMod-description []
synonym	"SulfanilicAcid" RELATED PSI-MS-label []
xref	DiffAvg: "155.00"
xref	DiffFormula: "(12)C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "155.004099"
xref	Formula: "(12)C 11 H 12 N 2 O 5 S 1"
xref	MassAvg: "284.05"
xref	MassMono: "284.046692"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00605 Sulfanilic Acid (SA), light C12 ! Sulfanilic Acid (SA), light C12

2.1219. MOD:01219 Sulfanilic Acid (SA), heavy C13 - site D

Table 1221. Term [MOD:01219]
id	MOD:01219
name	Sulfanilic Acid (SA), heavy C13 - site D
def	"modification from UniMod Chemical derivative -" [PubMed:9254591, PubMed:9750125, UniMod:286#D]
synonym	"Heavy Sulfanilic Acid (SA) C13" RELATED UniMod-description []
synonym	"SulfanilicAcid:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "161.02"
xref	DiffFormula: "(13)C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "161.024228"
xref	Formula: "(12)C 4 (13)C 6 H 10 N 2 O 5 S 1"
xref	MassAvg: "276.05"
xref	MassMono: "276.051171"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00606 Sulfanilic Acid (SA), heavy C13 ! Sulfanilic Acid (SA), heavy C13

2.1220. MOD:01220 Sulfanilic Acid (SA), heavy C13 - site E

Table 1222. Term [MOD:01220]
id	MOD:01220
name	Sulfanilic Acid (SA), heavy C13 - site E
def	"modification from UniMod Chemical derivative -" [PubMed:15121203, PubMed:9254591, UniMod:286#E]
synonym	"Heavy Sulfanilic Acid (SA) C13" RELATED UniMod-description []
synonym	"SulfanilicAcid:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "161.02"
xref	DiffFormula: "(13)C 6 H 5 N 1 O 2 S 1"
xref	DiffMono: "161.024228"
xref	Formula: "(12)C 5 (13)C 6 H 12 N 2 O 5 S 1"
xref	MassAvg: "290.07"
xref	MassMono: "290.066822"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00606 Sulfanilic Acid (SA), heavy C13 ! Sulfanilic Acid (SA), heavy C13

2.1221. MOD:01221 O-formyl-L-threonine

Table 1223. Term [MOD:01221]
id	MOD:01221
name	O-formyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-formyl-L-threonine." [PubMed:11861642, PubMed:15799070, UniMod:122#T]
comment	From UniMod: Can occur under CNBr cleavage conditions (70% HCOOH).
synonym	"Formyl" RELATED PSI-MS-label []
synonym	"Formylation" RELATED UniMod-description []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01483 O-formylated residue ! O-formylated residue

2.1222. MOD:01222 O-formyl-L-serine

Table 1224. Term [MOD:01222]
id	MOD:01222
name	O-formyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-formyl-L-serine." [PubMed:15627961, PubMed:15799070, UniMod:122#S]
comment	From UniMod: Can occur under CNBr cleavage conditions (70% HCOOH).
synonym	"Formyl" RELATED PSI-MS-label []
synonym	"Formylation" RELATED UniMod-description []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01483 O-formylated residue ! O-formylated residue

2.1223. MOD:01223 thioacylation of primary amines - site N-term

Table 1225. Term [MOD:01223]
id	MOD:01223
name	thioacylation of primary amines - site N-term
def	"modification from UniMod Other -" [OMSSA:41, PubMed:11710128, PubMed:3155470, PubMed:957432, UniMod:126#N-term]
comment	This UniMod entry is misdescribed as "thioacylation" [JSG].
synonym	"3,3-Dithio-bis-(sulfosuccinimidyl)propionate" RELATED UniMod-alternate []
synonym	"ntermpeptioacetyl" EXACT OMSSA-label []
synonym	"Thioacyl" RELATED PSI-MS-label []
synonym	"thioacylation of primary amines (N-term and Lys)" RELATED UniMod-description []
xref	DiffAvg: "88.12"
xref	DiffFormula: "C 3 H 4 O 1 S 1"
xref	DiffMono: "87.998286"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00497 3-sulfanylpropanoyl (N-term and Lys) ! 3-sulfanylpropanoyl (N-term and Lys)

2.1224. MOD:01224 thioacylation of primary amines - site K

Table 1226. Term [MOD:01224]
id	MOD:01224
name	thioacylation of primary amines - site K
def	"modification from UniMod Other -" [OMSSA:40, PubMed:11710128, PubMed:3155470, PubMed:957432, UniMod:126#K]
comment	This UniMod entry is misdescribed as "thioacylation" [JSG].
synonym	"3,3-Dithio-bis-(sulfosuccinimidyl)propionate" RELATED UniMod-alternate []
synonym	"thioacetylk" EXACT OMSSA-label []
synonym	"Thioacyl" RELATED PSI-MS-label []
synonym	"thioacylation of primary amines (N-term and Lys)" RELATED UniMod-description []
xref	DiffAvg: "88.12"
xref	DiffFormula: "C 3 H 4 O 1 S 1"
xref	DiffMono: "87.998286"
xref	Formula: "C 9 H 16 N 2 O 2 S 1"
xref	MassAvg: "216.30"
xref	MassMono: "216.093249"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00497 3-sulfanylpropanoyl (N-term and Lys) ! 3-sulfanylpropanoyl (N-term and Lys)

2.1225. MOD:01225 monofluorinated L-tyrosine

Table 1227. Term [MOD:01225]
id	MOD:01225
name	monofluorinated L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue into an L-fluorotyrosine." [OMSSA:46, PubMed:8069568, UniMod:127#Y]
comment	From UniMod: the citation appears to be correct, but the PMID is not and has been corrected [JSG].
synonym	"Fluoro" RELATED PSI-MS-label []
synonym	"fluorophenylalanine replacement of phenylalanine" RELATED UniMod-description []
synonym	"phef" EXACT OMSSA-label []
xref	DiffAvg: "17.99"
xref	DiffFormula: "F 1 H -1"
xref	DiffMono: "17.990578"
xref	Formula: "C 9 F 1 H 8 N 1 O 2"
xref	MassAvg: "181.17"
xref	MassMono: "181.053907"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue
is_a	MOD:00985 halogenated tyrosine ! halogenated tyrosine

2.1226. MOD:01226 monofluorinated L-tryptophan

Table 1228. Term [MOD:01226]
id	MOD:01226
name	monofluorinated L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to an L-fluorotryptophan." [PubMed:8069568, UniMod:127#W]
comment	From UniMod: the citation appears to be correct, but the PMID is not and has been corrected [JSG].
synonym	"Fluoro" RELATED PSI-MS-label []
synonym	"fluorophenylalanine replacement of phenylalanine" RELATED UniMod-description []
xref	DiffAvg: "17.99"
xref	DiffFormula: "F 1 H -1"
xref	DiffMono: "17.990578"
xref	Formula: "C 11 F 1 H 9 N 2 O 1"
xref	MassAvg: "204.20"
xref	MassMono: "204.069891"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue
is_a	MOD:01068 halogenated tryptophan ! halogenated tryptophan

2.1227. MOD:01227 monofluorinated L-phenylalanine

Table 1229. Term [MOD:01227]
id	MOD:01227
name	monofluorinated L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to an L-fluorophenylalanine." [DeltaMass:181, OMSSA:46, PubMed:8069568, UniMod:127#F]
comment	From UniMod: the citation appears to be correct, but the PMID is not and has been corrected. From DeltaMass: (element abbreviation in formula incorrect, mass incorrect, and aggregate not delta) Average Mass: 149 Formula: C9H8O1N1Fl1 Average Mass Change: 149 References:PE Sciex with no citation [JSG].
synonym	"Fluoro" RELATED PSI-MS-label []
synonym	"fluorophenylalanine replacement of phenylalanine" RELATED UniMod-description []
synonym	"phef" EXACT OMSSA-label []
xref	DiffAvg: "17.99"
xref	DiffFormula: "C 0 F 1 H -1 N 0 O 0"
xref	DiffMono: "17.990578"
xref	Formula: "C 9 F 1 H 8 N 1 O 1"
xref	MassAvg: "165.17"
xref	MassMono: "165.058992"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue
is_a	MOD:01066 halogenated phenylalanine ! halogenated phenylalanine

2.1228. MOD:01228 monoiodinated tyrosine

Table 1230. Term [MOD:01228]
id	MOD:01228
name	monoiodinated tyrosine
def	"A protein modification that effectively substitutes one hydrogen atom of an L-tyrosine residue with one iodine atom." [DeltaMass:0, OMSSA:65, PubMed:1326520, PubMed:15627961, PubMed:2026710, UniMod:129#Y]
comment	From DeltaMass: Average Mass: 289 [name misspelled "monoiodated" - JSG].
subset	PSI-MOD-slim
synonym	"I1Tyr" EXACT PSI-MOD-label []
synonym	"Iodination" RELATED UniMod-description []
synonym	"iodinationy" EXACT OMSSA-label []
synonym	"Iodo" RELATED PSI-MS-label []
xref	DiffAvg: "125.90"
xref	DiffFormula: "H -1 I 1"
xref	DiffMono: "125.896648"
xref	Formula: "C 9 H 8 I 1 N 1 O 2"
xref	MassAvg: "289.07"
xref	MassMono: "288.959976"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00500 monoiodinated residue ! monoiodinated residue
is_a	MOD:00998 iodinated tyrosine ! iodinated tyrosine

2.1229. MOD:01229 L-iodohistidine

Table 1231. Term [MOD:01229]
id	MOD:01229
name	L-iodohistidine
def	"A protein modification that effectively converts an L-histidine residue to an L-iodohistidine." [PubMed:15627961, PubMed:2026710, UniMod:129#H]
synonym	"I1His" EXACT PSI-MOD-label []
synonym	"Iodination" RELATED UniMod-description []
synonym	"Iodo" RELATED PSI-MS-label []
xref	DiffAvg: "125.90"
xref	DiffFormula: "C 0 H -1 I 1 N 0 O 0"
xref	DiffMono: "125.896648"
xref	Formula: "C 6 H 6 I 1 N 3 O 1"
xref	MassAvg: "263.04"
xref	MassMono: "262.955560"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00500 monoiodinated residue ! monoiodinated residue
is_a	MOD:01049 halogenated histidine ! halogenated histidine

2.1230. MOD:01230 Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form - site K

Table 1232. Term [MOD:01230]
id	MOD:01230
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form - site K
def	"modification from UniMod Isotopic label -" [PubMed:15602776, UniMod:365#K]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form" RELATED UniMod-description []
synonym	"ICPL" RELATED PSI-MS-label []
xref	DiffAvg: "105.02"
xref	DiffFormula: "(12)C 6 H 3 N 1 O 1"
xref	DiffMono: "105.021464"
xref	Formula: "(12)C 12 H 15 N 3 O 2"
xref	MassAvg: "233.12"
xref	MassMono: "233.116427"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00790 Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form ! Bruker Daltonics SERVA-ICPL™ quantification chemistry, light form

2.1231. MOD:01231 3x(13)C labeled N6-propanoyl-L-lysine

Table 1233. Term [MOD:01231]
id	MOD:01231
name	3x(13)C labeled N6-propanoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 3x(13)C labeled N6-propanoyl-L-lysine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:12442261, UniMod:59#K]
subset	PSI-MOD-slim
synonym	"Propionate labeling reagent heavy form (+3amu), N-term & K" RELATED UniMod-description []
synonym	"Propionyl:13C(3)" RELATED PSI-MS-label []
xref	DiffAvg: "59.04"
xref	DiffFormula: "(13)C 3 H 4 O 1"
xref	DiffMono: "59.036279"
xref	Formula: "(12)C 6 (13)C 3 H 16 N 2 O 2"
xref	MassAvg: "187.13"
xref	MassMono: "187.131242"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01398 N6-propanoyl-L-lysine ! N6-propanoyl-L-lysine

2.1232. MOD:01232 3x(12)C labeled N6-propanoyl-L-lysine

Table 1234. Term [MOD:01232]
id	MOD:01232
name	3x(12)C labeled N6-propanoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 3x(12)C labeled N6-propanoyl-L-lysine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:58#K]
subset	PSI-MOD-slim
synonym	"Propionate labeling reagent light form (N-term & K)" RELATED UniMod-description []
synonym	"Propionyl" RELATED PSI-MS-label []
xref	DiffAvg: "56.03"
xref	DiffFormula: "(12)C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "(12)C 9 H 16 N 2 O 2"
xref	MassAvg: "184.12"
xref	MassMono: "184.121178"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01398 N6-propanoyl-L-lysine ! N6-propanoyl-L-lysine

2.1233. MOD:01233 3x(2)H labeled N6-acetyl-L-lysine

Table 1235. Term [MOD:01233]
id	MOD:01233
name	3x(2)H labeled N6-acetyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 3x(2)H labeled N6-acetyl-L-lysine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:56#K]
subset	PSI-MOD-slim
synonym	"Acetate labeling reagent (N-term & K) (heavy form, +3amu)" RELATED UniMod-description []
synonym	"Acetyl:2H(3)" RELATED PSI-MS-label []
xref	DiffAvg: "45.03"
xref	DiffFormula: "C 2 (1)H -1 (2)H 3 O 1"
xref	DiffMono: "45.029395"
xref	Formula: "C 8 (1)H 11 (2)H 3 N 2 O 2"
xref	MassAvg: "173.12"
xref	MassMono: "173.124358"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00064 N6-acetyl-L-lysine ! N6-acetyl-L-lysine
is_a	MOD:00449 acetate labeling reagent (N-term) (heavy form, +3amu) ! acetate labeling reagent (N-term) (heavy form, +3amu)

2.1234. MOD:01234 (18)O monosubstituted L-serine

Table 1236. Term [MOD:01234]
id	MOD:01234
name	(18)O monosubstituted L-serine
def	"modification from UniMod Isotopic label - alkaline phosphatase to dephosphorylate" [PubMed:11467524, UniMod:258#S]
subset	PSI-MOD-slim
synonym	"Label:18O(1)" RELATED PSI-MS-label []
synonym	"O18 Labeling" RELATED UniMod-description []
xref	DiffAvg: "2.00"
xref	DiffFormula: "(16)O -1 (18)O 1"
xref	DiffMono: "2.004246"
xref	Formula: "C 3 H 5 N 1 (16)O 1 (18)O 1"
xref	MassAvg: "89.04"
xref	MassMono: "89.036275"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00581 (18)O monosubstituted residue ! (18)O monosubstituted residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1235. MOD:01235 (18)O monosubstituted L-threonine

Table 1237. Term [MOD:01235]
id	MOD:01235
name	(18)O monosubstituted L-threonine
def	"modification from UniMod Isotopic label - alkaline phosphatase to dephosphorylate" [PubMed:11467524, PubMed:15549660, UniMod:258#T]
subset	PSI-MOD-slim
synonym	"Label:18O(1)" RELATED PSI-MS-label []
synonym	"O18 Labeling" RELATED UniMod-description []
xref	DiffAvg: "2.00"
xref	DiffFormula: "(16)O -1 (18)O 1"
xref	DiffMono: "2.004246"
xref	Formula: "C 4 H 7 N 1 (16)O 1 (18)O 1"
xref	MassAvg: "103.05"
xref	MassMono: "103.051925"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00581 (18)O monosubstituted residue ! (18)O monosubstituted residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1236. MOD:01236 (18)O monosubstituted L-tyrosine

Table 1238. Term [MOD:01236]
id	MOD:01236
name	(18)O monosubstituted L-tyrosine
def	"modification from UniMod Isotopic label - alkaline phosphatase to dephosphorylate" [PubMed:11467524, PubMed:15549660, UniMod:258#Y]
subset	PSI-MOD-slim
synonym	"Label:18O(1)" RELATED PSI-MS-label []
synonym	"O18 Labeling" RELATED UniMod-description []
xref	DiffAvg: "2.00"
xref	DiffFormula: "(16)O -1 (18)O 1"
xref	DiffMono: "2.004246"
xref	Formula: "C 9 H 9 N 1 (16)O 1 (18)O 1"
xref	MassAvg: "165.07"
xref	MassMono: "165.067575"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00581 (18)O monosubstituted residue ! (18)O monosubstituted residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1237. MOD:01237 cysteine 4-hydroxynonenal adduct

Table 1239. Term [MOD:01237]
id	MOD:01237
name	cysteine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-cysteine residue with 4-hydroxynonenal." [PubMed:11327326, PubMed:15133838, PubMed:9629898, UniMod:53#C]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"4-hydroxynonenal (HNE)" RELATED UniMod-description []
synonym	"HNE" RELATED PSI-MS-label []
xref	DiffAvg: "156.22"
xref	DiffFormula: "C 9 H 16 O 2"
xref	DiffMono: "156.115030"
xref	Formula: "C 12 H 21 N 1 O 3 S 1"
xref	MassAvg: "259.36"
xref	MassMono: "259.124215"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00446 4-hydroxynonenal adduct ! 4-hydroxynonenal adduct

2.1238. MOD:01238 lysine 4-hydroxynonenal adduct

Table 1240. Term [MOD:01238]
id	MOD:01238
name	lysine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-lysine residue with 4-hydroxynonenal." [PubMed:11327326, PubMed:15133838, PubMed:9629898, UniMod:53#K]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"4-hydroxynonenal (HNE)" RELATED UniMod-description []
synonym	"HNE" RELATED PSI-MS-label []
xref	DiffAvg: "156.22"
xref	DiffFormula: "C 9 H 16 O 2"
xref	DiffMono: "156.115030"
xref	Formula: "C 15 H 28 N 2 O 3"
xref	MassAvg: "284.40"
xref	MassMono: "284.209993"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00446 4-hydroxynonenal adduct ! 4-hydroxynonenal adduct

2.1239. MOD:01239 histidine 4-hydroxynonenal adduct

Table 1241. Term [MOD:01239]
id	MOD:01239
name	histidine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-histidine residue with 4-hydroxynonenal." [PubMed:10717661, PubMed:11327326, PubMed:15133838, UniMod:53#H]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"4-hydroxynonenal (HNE)" RELATED UniMod-description []
synonym	"HNE" RELATED PSI-MS-label []
xref	DiffAvg: "156.22"
xref	DiffFormula: "C 9 H 16 O 2"
xref	DiffMono: "156.115030"
xref	Formula: "C 15 H 23 N 3 O 3"
xref	MassAvg: "293.37"
xref	MassMono: "293.173942"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00446 4-hydroxynonenal adduct ! 4-hydroxynonenal adduct

2.1240. MOD:01240 ubiquitination signature tetrapeptidyl lysine

Table 1242. Term [MOD:01240]
id	MOD:01240
name	ubiquitination signature tetrapeptidyl lysine
def	"A protein modification that crosslinks the N6-amino of a peptidyl lysine with the carboxyl of leucyl-arginyl-glycyl-glycine, the C-terminal tetrapeptide of ubiquitin." [PubMed:10504701, UniMod:535]
synonym	"LeuArgGlyGly" RELATED PSI-MS-label []
synonym	"Ubiquitination" RELATED UniMod-description []
xref	DiffAvg: "383.45"
xref	DiffFormula: "C 16 H 29 N 7 O 4"
xref	DiffMono: "383.228102"
xref	Formula: "C 22 H 41 N 9 O 5"
xref	MassAvg: "511.63"
xref	MassMono: "511.323065"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
relationship	derives_from MOD:01148 ubiquitinylated lysine ! ubiquitinylated lysine

2.1241. MOD:01241 3x(2)H labeled L-aspartic acid 4-methyl ester

Table 1243. Term [MOD:01241]
id	MOD:01241
name	3x(2)H labeled L-aspartic acid 4-methyl ester
def	"A protein modification that effectively converts an L-lysine residue to 3x(2)H labeled L-aspartic acid 4-methyl ester." [OMSSA:19, PubMed:12185208, UniMod:298#D]
synonym	"deuterated methyl ester" RELATED UniMod-description []
synonym	"Methyl:2H(3)" RELATED PSI-MS-label []
synonym	"trideuteromethyld" EXACT OMSSA-label []
xref	DiffAvg: "17.03"
xref	DiffFormula: "C 1 (1)H -1 (2)H 3"
xref	DiffMono: "17.034480"
xref	Formula: "C 5 (1)H 4 (2)H 3 N 1 O 3"
xref	MassAvg: "132.06"
xref	MassMono: "132.061423"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00617 3x(2)H residue methyl ester ! 3x(2)H residue methyl ester
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
relationship	derives_from MOD:01181 L-aspartic acid 4-methyl ester ! L-aspartic acid 4-methyl ester

2.1242. MOD:01242 3x(2)H labeled L-glutamic acid 5-methyl ester

Table 1244. Term [MOD:01242]
id	MOD:01242
name	3x(2)H labeled L-glutamic acid 5-methyl ester
def	"A protein modification that effectively converts an L-lysine residue to 3x(2)H labeled L-glutamic acid 5-methyl ester." [OMSSA:20, PubMed:1326520, UniMod:298#E]
synonym	"deuterated methyl ester" RELATED UniMod-description []
synonym	"Methyl:2H(3)" RELATED PSI-MS-label []
synonym	"trideuteromethyle" EXACT OMSSA-label []
xref	DiffAvg: "17.03"
xref	DiffFormula: "C 1 (1)H -1 (2)H 3"
xref	DiffMono: "17.034480"
xref	Formula: "C 6 (1)H 6 (2)H 3 N 1 O 3"
xref	MassAvg: "146.08"
xref	MassMono: "146.077073"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00617 3x(2)H residue methyl ester ! 3x(2)H residue methyl ester
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
relationship	derives_from MOD:00081 L-glutamic acid 5-methyl ester (Glu) ! L-glutamic acid 5-methyl ester (Glu)

2.1243. MOD:01243 potassium carboxylate C-terminal residue

Table 1245. Term [MOD:01243]
id	MOD:01243
name	potassium carboxylate C-terminal residue
def	"A protein modification that effectively converts a C-terminal residue to the potassium carboxylate salt." [UniMod:530#C-term]
synonym	"Cation:K" RELATED PSI-MS-label []
synonym	"Replacement of proton by potassium" RELATED UniMod-description []
xref	DiffAvg: "38.09"
xref	DiffFormula: "H -1 K 1"
xref	DiffMono: "37.955882"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "C-term"
is_a	MOD:01072 monopotassium salt ! monopotassium salt

2.1244. MOD:01244 potassium L-glutamate

Table 1246. Term [MOD:01244]
id	MOD:01244
name	potassium L-glutamate
def	"A protein modification that effectively converts an L-glutamioc acid residue to the potassium glutamate salt." [UniMod:530#E]
synonym	"Cation:K" RELATED PSI-MS-label []
synonym	"Replacement of proton by potassium" RELATED UniMod-description []
xref	DiffAvg: "38.09"
xref	DiffFormula: "H -1 K 1"
xref	DiffMono: "37.955882"
xref	Formula: "C 5 H 6 K 1 N 1 O 3"
xref	MassAvg: "167.21"
xref	MassMono: "166.998475"
xref	Origin: "E"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01072 monopotassium salt ! monopotassium salt

2.1245. MOD:01245 potassium L-aspartate

Table 1247. Term [MOD:01245]
id	MOD:01245
name	potassium L-aspartate
def	"A protein modification that effectively converts an L-aspartic acid residue to the potassium aspartate salt." [UniMod:530#D]
synonym	"Cation:K" RELATED PSI-MS-label []
synonym	"Replacement of proton by potassium" RELATED UniMod-description []
xref	DiffAvg: "38.09"
xref	DiffFormula: "H -1 K 1"
xref	DiffMono: "37.955882"
xref	Formula: "C 4 H 4 K 1 N 1 O 3"
xref	MassAvg: "153.18"
xref	MassMono: "152.982825"
xref	Origin: "D"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01072 monopotassium salt ! monopotassium salt

2.1246. MOD:01246 fucosylated -site S

Table 1248. Term [MOD:01246]
id	MOD:01246
name	fucosylated -site S
def	"OBSOLETE because redundant and identical to MOD:00812 after formula correction. Remap to MOD:00812." [PubMed:11344537, PubMed:15189151, PubMed:3311742, PubMed:3578767, UniMod:295#S]
synonym	"dHex" RELATED PSI-MS-label []
synonym	"Fucose" RELATED UniMod-description []
xref	DiffAvg: "147.15"
xref	DiffFormula: "C 6 H 11 O 4"
xref	DiffMono: "147.065734"
xref	Formula: "C 9 H 16 N 1 O 6"
xref	MassAvg: "234.23"
xref	MassMono: "234.097762"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1247. MOD:01247 fucosylated -site T

Table 1249. Term [MOD:01247]
id	MOD:01247
name	fucosylated -site T
def	"OBSOLETE because redundant and identical to MOD:00813 after formula correction. Remap to MOD:00813." [PubMed:11344537, PubMed:11857757, PubMed:15189151, UniMod:295#T]
synonym	"dHex" RELATED PSI-MS-label []
synonym	"Fucose" RELATED UniMod-description []
xref	DiffAvg: "147.15"
xref	DiffFormula: "C 6 H 11 O 4"
xref	DiffMono: "147.065734"
xref	Formula: "C 10 H 18 N 1 O 6"
xref	MassAvg: "248.26"
xref	MassMono: "248.113412"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1248. MOD:01248 iodouridine monophosphate derivatized tyrosine

Table 1250. Term [MOD:01248]
id	MOD:01248
name	iodouridine monophosphate derivatized tyrosine
def	"A protein modification that is produced by reaction of iodouridine monophosphate, or a polynucleotide containing iodouridine, with an L-tyrosine residue to form an ether linkage." [PubMed:11112526, PubMed:11567090, PubMed:6540775, UniMod:292#Y]
comment	This has an ether linkage and not a phosphodiester linkage with UMP.
synonym	"Cross-link of (Iodo)-uracil MP with W,F,Y" RELATED UniMod-description []
synonym	"IodoU-AMP" RELATED PSI-MS-label []
xref	DiffAvg: "322.17"
xref	DiffFormula: "C 9 H 11 N 2 O 9 P 1"
xref	DiffMono: "322.020217"
xref	Formula: "C 18 H 20 N 3 O 11 P 1"
xref	MassAvg: "485.34"
xref	MassMono: "485.083545"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00611 iodouridine monophosphate derivatized residue ! iodouridine monophosphate derivatized residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1249. MOD:01249 iodouridine monophosphate derivatized tryptophan

Table 1251. Term [MOD:01249]
id	MOD:01249
name	iodouridine monophosphate derivatized tryptophan
def	"A protein modification that is produced by reaction of iodouridine monophosphate, or a polynucleotide containing iodouridine, with an L-tryptophan residue." [PubMed:11112526, PubMed:11567090, PubMed:6540775, UniMod:292#W]
comment	This has a carbon-nitrogen linkage and not a phosphodiester linkage with UMP.
synonym	"Cross-link of (Iodo)-uracil MP with W,F,Y" RELATED UniMod-description []
synonym	"IodoU-AMP" RELATED PSI-MS-label []
xref	DiffAvg: "322.17"
xref	DiffFormula: "C 9 H 11 N 2 O 9 P 1"
xref	DiffMono: "322.020217"
xref	Formula: "C 20 H 21 N 4 O 10 P 1"
xref	MassAvg: "508.38"
xref	MassMono: "508.099530"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00611 iodouridine monophosphate derivatized residue ! iodouridine monophosphate derivatized residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1250. MOD:01250 iodouridine monophosphate derivatized phenylalanine

Table 1252. Term [MOD:01250]
id	MOD:01250
name	iodouridine monophosphate derivatized phenylalanine
def	"A protein modification that is produced by reaction of iodouridine monophosphate, or a polynucleotide containing iodouridine, with an L-phenylalanine residue." [PubMed:11112526, PubMed:11567090, PubMed:6540775, UniMod:292#F]
comment	This has a carbon-carbon linkage and not a phosphodiester linkage with UMP.
synonym	"Cross-link of (Iodo)-uracil MP with W,F,Y" RELATED UniMod-description []
synonym	"IodoU-AMP" RELATED PSI-MS-label []
xref	DiffAvg: "322.17"
xref	DiffFormula: "C 9 H 11 N 2 O 9 P 1"
xref	DiffMono: "322.020217"
xref	Formula: "C 18 H 20 N 3 O 10 P 1"
xref	MassAvg: "469.34"
xref	MassMono: "469.088630"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00611 iodouridine monophosphate derivatized residue ! iodouridine monophosphate derivatized residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.1251. MOD:01251 N6-[3-(carboxamidomethylthio)propanoyl]lysine

Table 1253. Term [MOD:01251]
id	MOD:01251
name	N6-[3-(carboxamidomethylthio)propanoyl]lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-[3-(carboxamidomethylthio)propanoyl]lysine." [PubMed:15121203, UniMod:293#K]
synonym	"3-(carbamidomethylthio)propanoyl" RELATED UniMod-description []
synonym	"CAMthiopropanoyl" RELATED PSI-MS-label []
xref	DiffAvg: "145.18"
xref	DiffFormula: "C 5 H 7 N 1 O 2 S 1"
xref	DiffMono: "145.019749"
xref	Formula: "C 11 H 19 N 3 O 3 S 1"
xref	MassAvg: "273.35"
xref	MassMono: "273.114712"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00612 3-(carboxamidomethylthio)propanoylated residue ! 3-(carboxamidomethylthio)propanoylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1252. MOD:01252 5-hydro-5-methylimidazol-4-one, methylglyoxal arginine adduct (+54 amu)

Table 1254. Term [MOD:01252]
id	MOD:01252
name	5-hydro-5-methylimidazol-4-one, methylglyoxal arginine adduct (+54 amu)
def	"OBSOLETE because redundant and identical to MOD:00933. Remap to MOD:00933." [PubMed:9448752, UniMod:319#R]
synonym	"Delta:H(2)C(3)O(1)" RELATED PSI-MS-label []
synonym	"MDA adduct +54" RELATED UniMod-description []
xref	DiffAvg: "54.05"
xref	DiffFormula: "C 3 H 2 O 1"
xref	DiffMono: "54.010565"
xref	Formula: "C 9 H 14 N 4 O 2"
xref	MassAvg: "210.24"
xref	MassMono: "210.111676"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1253. MOD:01253 malondialdehyde lysine adduct (+54 amu)

Table 1255. Term [MOD:01253]
id	MOD:01253
name	malondialdehyde lysine adduct (+54 amu)
def	"modification from UniMod Chemical derivative - Malondialdehyde (MDA) adduct" [UniMod:319#K]
synonym	"Delta:H(2)C(3)O(1)" RELATED PSI-MS-label []
synonym	"MDA adduct +54" RELATED UniMod-description []
xref	DiffAvg: "54.05"
xref	DiffFormula: "C 3 H 2 O 1"
xref	DiffMono: "54.010565"
xref	Formula: "C 9 H 14 N 2 O 2"
xref	MassAvg: "182.22"
xref	MassMono: "182.105528"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00630 C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine. ! C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine.
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1254. MOD:01254 4x(2)H labeled dimethylated L-lysine

Table 1256. Term [MOD:01254]
id	MOD:01254
name	4x(2)H labeled dimethylated L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4x(2)H labeled dimethylated L-lysine." [OMSSA:189, PubMed:14670044, UniMod:199#K]
subset	PSI-MOD-slim
synonym	"DiMethyl-CHD2" RELATED UniMod-description []
synonym	"Dimethyl:2H(4)" RELATED PSI-MS-label []
synonym	"mod189" EXACT OMSSA-label []
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 2 (2)H 4"
xref	DiffMono: "32.056407"
xref	Formula: "C 8 H 12 (2)H 4 N 2 O 1"
xref	MassAvg: "160.15"
xref	MassMono: "160.151370"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00552 4x(2)H labeled dimethylated residue ! 4x(2)H labeled dimethylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
relationship	derives_from MOD:00084 N6,N6-dimethyl-L-lysine ! N6,N6-dimethyl-L-lysine

2.1255. MOD:01255 S-(2-sulfanylethyl)cysteine (Ser)

Table 1257. Term [MOD:01255]
id	MOD:01255
name	S-(2-sulfanylethyl)cysteine (Ser)
def	"A protein modification that effectively converts an L-serine residue to S-(2-sulfanylethyl)cysteine." [PubMed:11507762, UniMod:200#S]
synonym	"EDT" RELATED UniMod-description []
synonym	"Ethanedithiol" RELATED PSI-MS-label []
synonym	"S-(2-mercaptoethyl)cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "76.18"
xref	DiffFormula: "C 2 H 4 O -1 S 2"
xref	DiffMono: "75.980528"
xref	Formula: "C 5 H 9 N 1 O 1 S 2"
xref	MassAvg: "163.25"
xref	MassMono: "163.012556"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00553 1,2-ethanedithiol modified residue ! 1,2-ethanedithiol modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1256. MOD:01256 3-methyl-S-(2-sulfanylethyl)cysteine (Thr)

Table 1258. Term [MOD:01256]
id	MOD:01256
name	3-methyl-S-(2-sulfanylethyl)cysteine (Thr)
def	"A protein modification that effectively converts an L-threonine residue to 3-methyl-S-(2-sulfanylethyl)cysteine." [PubMed:11507762, UniMod:200#T]
synonym	"beta-methyl-S-(2-mercaptoethyl)cysteine" EXACT PSI-MOD-alternate []
synonym	"EDT" RELATED UniMod-description []
synonym	"Ethanedithiol" RELATED PSI-MS-label []
xref	DiffAvg: "76.18"
xref	DiffFormula: "C 2 H 4 O -1 S 2"
xref	DiffMono: "75.980528"
xref	Formula: "C 6 H 11 N 1 O 1 S 2"
xref	MassAvg: "177.28"
xref	MassMono: "177.028206"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00553 1,2-ethanedithiol modified residue ! 1,2-ethanedithiol modified residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1257. MOD:01257 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate - site K

Table 1259. Term [MOD:01257]
id	MOD:01257
name	6-aminoquinolyl-N-hydroxysuccinimidyl carbamate - site K
def	"modification from UniMod Chemical derivative -" [PubMed:12716131, PubMed:14997490, UniMod:194#K]
synonym	"6-aminoquinolyl-N-hydroxysuccinimidyl carbamate" RELATED UniMod-description []
synonym	"AccQTag" RELATED PSI-MS-label []
xref	DiffAvg: "170.17"
xref	DiffFormula: "C 10 H 6 N 2 O 1"
xref	DiffMono: "170.048013"
xref	Formula: "C 16 H 18 N 4 O 2"
xref	MassAvg: "298.35"
xref	MassMono: "298.142976"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00547 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate ! 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate

2.1258. MOD:01258 N-methylmaleimide - site C

Table 1260. Term [MOD:01258]
id	MOD:01258
name	N-methylmaleimide - site C
def	"modification from UniMod Chemical derivative -" [PubMed:9448752, UniMod:314#C]
synonym	"Nmethylmaleimide" RELATED PSI-MS-label []
synonym	"Nmethylmaleimide" RELATED UniMod-description []
xref	DiffAvg: "111.10"
xref	DiffFormula: "C 5 H 5 N 1 O 2"
xref	DiffMono: "111.032028"
xref	Formula: "C 8 H 10 N 2 O 3 S 1"
xref	MassAvg: "214.24"
xref	MassMono: "214.041213"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00625 N-methylmaleimide derivatized residue ! N-methylmaleimide derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1259. MOD:01259 N-methylmaleimide - site K

Table 1261. Term [MOD:01259]
id	MOD:01259
name	N-methylmaleimide - site K
def	"modification from UniMod Chemical derivative -" [PubMed:9448752, UniMod:314#K]
synonym	"Nmethylmaleimide" RELATED PSI-MS-label []
synonym	"Nmethylmaleimide" RELATED UniMod-description []
xref	DiffAvg: "111.10"
xref	DiffFormula: "C 5 H 5 N 1 O 2"
xref	DiffMono: "111.032028"
xref	Formula: "C 11 H 17 N 3 O 3"
xref	MassAvg: "239.27"
xref	MassMono: "239.126991"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00625 N-methylmaleimide derivatized residue ! N-methylmaleimide derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1260. MOD:01260 nucleophilic addtion to cytopiloyne - site Y

Table 1262. Term [MOD:01260]
id	MOD:01260
name	nucleophilic addtion to cytopiloyne - site Y
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:270#Y]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 28 H 31 N 1 O 9"
xref	MassAvg: "525.55"
xref	MassMono: "525.199882"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1261. MOD:01261 nucleophilic addtion to cytopiloyne - site S

Table 1263. Term [MOD:01261]
id	MOD:01261
name	nucleophilic addtion to cytopiloyne - site S
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:270#C]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 22 H 27 N 1 O 9"
xref	MassAvg: "449.46"
xref	MassMono: "449.168581"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1262. MOD:01262 nucleophilic addtion to cytopiloyne - site R

Table 1264. Term [MOD:01262]
id	MOD:01262
name	nucleophilic addtion to cytopiloyne - site R
def	"modification from UniMod Chemical derivative -" [PubMed:12590383, PubMed:15549660, UniMod:270#R]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 25 H 34 N 4 O 8"
xref	MassAvg: "518.57"
xref	MassMono: "518.237664"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.1263. MOD:01263 nucleophilic addtion to cytopiloyne - site K

Table 1265. Term [MOD:01263]
id	MOD:01263
name	nucleophilic addtion to cytopiloyne - site K
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:270#K]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 25 H 34 N 2 O 8"
xref	MassAvg: "490.55"
xref	MassMono: "490.231516"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1264. MOD:01264 nucleophilic addtion to cytopiloyne - site C

Table 1266. Term [MOD:01264]
id	MOD:01264
name	nucleophilic addtion to cytopiloyne - site C
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:270#C]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 22 H 27 N 1 O 8 S 1"
xref	MassAvg: "465.52"
xref	MassMono: "465.145738"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1265. MOD:01265 nucleophilic addtion to cytopiloyne - site P

Table 1267. Term [MOD:01265]
id	MOD:01265
name	nucleophilic addtion to cytopiloyne - site P
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:270#P]
synonym	"Cytopiloyne" RELATED PSI-MS-label []
synonym	"nucleophilic addtion to cytopiloyne" RELATED UniMod-description []
xref	DiffAvg: "362.38"
xref	DiffFormula: "C 19 H 22 O 7"
xref	DiffMono: "362.136553"
xref	Formula: "C 24 H 29 N 1 O 8"
xref	MassAvg: "459.50"
xref	MassMono: "459.189317"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00590 nucleophilic addtion to cytopiloyne ! nucleophilic addtion to cytopiloyne
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.1266. MOD:01266 nucleophilic addition to cytopiloyne+H2O - site C

Table 1268. Term [MOD:01266]
id	MOD:01266
name	nucleophilic addition to cytopiloyne+H2O - site C
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:271#C]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 22 H 29 N 1 O 9 S 1"
xref	MassAvg: "483.53"
xref	MassMono: "483.156303"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1267. MOD:01267 nucleophilic addition to cytopiloyne+H2O - site K

Table 1269. Term [MOD:01267]
id	MOD:01267
name	nucleophilic addition to cytopiloyne+H2O - site K
def	"modification from UniMod Chemical derivative -" [PubMed:11746907, PubMed:15549660, UniMod:271#K]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 25 H 36 N 2 O 9"
xref	MassAvg: "508.57"
xref	MassMono: "508.242081"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1268. MOD:01268 nucleophilic addition to cytopiloyne+H2O - site T

Table 1270. Term [MOD:01268]
id	MOD:01268
name	nucleophilic addition to cytopiloyne+H2O - site T
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:271#T]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 23 H 31 N 1 O 10"
xref	MassAvg: "481.50"
xref	MassMono: "481.194796"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1269. MOD:01269 nucleophilic addition to cytopiloyne+H2O - site R

Table 1271. Term [MOD:01269]
id	MOD:01269
name	nucleophilic addition to cytopiloyne+H2O - site R
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:271#R]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 25 H 36 N 4 O 9"
xref	MassAvg: "536.58"
xref	MassMono: "536.248229"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.1270. MOD:01270 nucleophilic addition to cytopiloyne+H2O - site S

Table 1272. Term [MOD:01270]
id	MOD:01270
name	nucleophilic addition to cytopiloyne+H2O - site S
def	"modification from UniMod Chemical derivative -" [PubMed:14670044, PubMed:15549660, UniMod:271#S]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 22 H 29 N 1 O 10"
xref	MassAvg: "467.47"
xref	MassMono: "467.179146"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1271. MOD:01271 nucleophilic addition to cytopiloyne+H2O - site Y

Table 1273. Term [MOD:01271]
id	MOD:01271
name	nucleophilic addition to cytopiloyne+H2O - site Y
def	"modification from UniMod Chemical derivative -" [PubMed:15549660, UniMod:271#Y]
synonym	"Cytopiloyne+water" RELATED PSI-MS-label []
synonym	"nucleophilic addition to cytopiloyne+H2O" RELATED UniMod-description []
xref	DiffAvg: "380.39"
xref	DiffFormula: "C 19 H 24 O 8"
xref	DiffMono: "380.147118"
xref	Formula: "C 28 H 33 N 1 O 10"
xref	MassAvg: "543.57"
xref	MassMono: "543.210446"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00591 nucleophilic addition to cytopiloyne+H2O ! nucleophilic addition to cytopiloyne+H2O
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1272. MOD:01272 iminobiotinylation - site K

Table 1274. Term [MOD:01272]
id	MOD:01272
name	iminobiotinylation - site K
def	"modification from UniMod Chemical derivative -" [PubMed:9750125, UniMod:89#K]
synonym	"Iminobiotin" RELATED PSI-MS-label []
synonym	"Iminobiotinylation" RELATED UniMod-description []
xref	DiffAvg: "225.31"
xref	DiffFormula: "C 10 H 15 N 3 O 1 S 1"
xref	DiffMono: "225.093583"
xref	Formula: "C 16 H 27 N 5 O 2 S 1"
xref	MassAvg: "353.49"
xref	MassMono: "353.188546"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00467 iminobiotinyl modified residue ! iminobiotinyl modified residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1273. MOD:01273 O-[4-(2-aminoethyl)benzenesulfonyl] serine

Table 1275. Term [MOD:01273]
id	MOD:01273
name	O-[4-(2-aminoethyl)benzenesulfonyl] serine
def	"A protein modification that is produced by formation of an adduct with 4-(2-aminoethyl)benzenesulfonyl fluoride, AEBS, and an L-serine residue." [PubMed:15283597, PubMed:8597590, UniMod:276#S]
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "C 11 H 14 N 2 O 4 S 1"
xref	MassAvg: "270.30"
xref	MassMono: "270.067428"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue ! 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1274. MOD:01274 N'-[4-(2-aminoethyl)benzenesulfonyl] derivatized histidine

Table 1276. Term [MOD:01274]
id	MOD:01274
name	N'-[4-(2-aminoethyl)benzenesulfonyl] derivatized histidine
def	"A protein modification that is produced by formation of an adduct with 4-(2-aminoethyl)benzenesulfonyl fluoride, AEBS, and an L-histidine residue." [PubMed:8597590, UniMod:276#H]
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "C 14 H 16 N 4 O 3 S 1"
xref	MassAvg: "320.37"
xref	MassMono: "320.094311"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue ! 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1275. MOD:01275 N6-[4-(2-aminoethyl)benzenesulfonyl]lysine

Table 1277. Term [MOD:01275]
id	MOD:01275
name	N6-[4-(2-aminoethyl)benzenesulfonyl]lysine
def	"A protein modification that is produced by formation of an adduct with 4-(2-aminoethyl)benzenesulfonyl fluoride, AEBS, and an L-lysine residue." [PubMed:8597590, UniMod:276#K]
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "C 14 H 21 N 3 O 3 S 1"
xref	MassAvg: "311.40"
xref	MassMono: "311.130363"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue ! 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1276. MOD:01276 O4'-[4-(2-aminoethyl)benzenesulfonyl]tyrosine

Table 1278. Term [MOD:01276]
id	MOD:01276
name	O4'-[4-(2-aminoethyl)benzenesulfonyl]tyrosine
def	"A protein modification that is produced by formation of an adduct with 4-(2-aminoethyl)benzenesulfonyl fluoride, AEBS, and an L-tyrosine residue." [PubMed:10906242, PubMed:8597590, UniMod:276#Y]
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "C 17 H 18 N 2 O 4 S 1"
xref	MassAvg: "346.40"
xref	MassMono: "346.098728"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue ! 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1277. MOD:01277 crotonaldehyde - site C

Table 1279. Term [MOD:01277]
id	MOD:01277
name	crotonaldehyde - site C
def	"modification from UniMod Other -" [PubMed:11283024, UniMod:253#C]
synonym	"Crotonaldehyde" RELATED PSI-MS-label []
synonym	"Crotonaldehyde" RELATED UniMod-description []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "C 7 H 11 N 1 O 2 S 1"
xref	MassAvg: "173.23"
xref	MassMono: "173.051050"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00576 crotonaldehyde ! crotonaldehyde
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1278. MOD:01278 crotonaldehyde - site K

Table 1280. Term [MOD:01278]
id	MOD:01278
name	crotonaldehyde - site K
def	"modification from UniMod Other -" [PubMed:11283024, UniMod:253#K]
synonym	"Crotonaldehyde" RELATED PSI-MS-label []
synonym	"Crotonaldehyde" RELATED UniMod-description []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "C 10 H 18 N 2 O 2"
xref	MassAvg: "198.27"
xref	MassMono: "198.136828"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00576 crotonaldehyde ! crotonaldehyde
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1279. MOD:01279 crotonaldehyde - site H

Table 1281. Term [MOD:01279]
id	MOD:01279
name	crotonaldehyde - site H
def	"modification from UniMod Other -" [PubMed:11283024, PubMed:1443554, UniMod:253#H]
synonym	"Crotonaldehyde" RELATED PSI-MS-label []
synonym	"Crotonaldehyde" RELATED UniMod-description []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "C 10 H 13 N 3 O 2"
xref	MassAvg: "207.23"
xref	MassMono: "207.100777"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00576 crotonaldehyde ! crotonaldehyde
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1280. MOD:01280 EDT-iodo-PEO-biotin - site T

Table 1282. Term [MOD:01280]
id	MOD:01280
name	EDT-iodo-PEO-biotin - site T
def	"modification from UniMod Chemical derivative -" [PubMed:11857757, PubMed:12175151, UniMod:118#T]
synonym	"EDT-iodo-PEO-biotin" RELATED UniMod-description []
synonym	"EDT-iodoacetyl-PEO-biotin" RELATED PSI-MS-label []
xref	DiffAvg: "490.70"
xref	DiffFormula: "C 20 H 34 N 4 O 4 S 3"
xref	DiffMono: "490.174219"
xref	Formula: "C 24 H 41 N 5 O 6 S 3"
xref	MassAvg: "591.80"
xref	MassMono: "591.221897"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00490 EDT-iodo-PEO-biotin ! EDT-iodo-PEO-biotin
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1281. MOD:01281 EDT-iodo-PEO-biotin - site S

Table 1283. Term [MOD:01281]
id	MOD:01281
name	EDT-iodo-PEO-biotin - site S
def	"modification from UniMod Chemical derivative -" [PubMed:16335955, UniMod:118#S]
synonym	"EDT-iodo-PEO-biotin" RELATED UniMod-description []
synonym	"EDT-iodoacetyl-PEO-biotin" RELATED PSI-MS-label []
xref	DiffAvg: "490.70"
xref	DiffFormula: "C 20 H 34 N 4 O 4 S 3"
xref	DiffMono: "490.174219"
xref	Formula: "C 23 H 39 N 5 O 6 S 3"
xref	MassAvg: "577.77"
xref	MassMono: "577.206247"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00490 EDT-iodo-PEO-biotin ! EDT-iodo-PEO-biotin
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1282. MOD:01282 acrolein addition +56 - site H

Table 1284. Term [MOD:01282]
id	MOD:01282
name	acrolein addition +56 - site H
def	"modification from UniMod Other -" [PubMed:10825247, PubMed:15541752, UniMod:206#H]
synonym	"Acrolein addition +56" RELATED UniMod-description []
synonym	"Delta:H(4)C(3)O(1)" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "C 9 H 11 N 3 O 2"
xref	MassAvg: "193.21"
xref	MassMono: "193.085127"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00557 acrolein addition +56 ! acrolein addition +56
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1283. MOD:01283 acrolein addition +56 - site K

Table 1285. Term [MOD:01283]
id	MOD:01283
name	acrolein addition +56 - site K
def	"modification from UniMod Other -" [PubMed:10825247, PubMed:15541752, UniMod:206#K]
synonym	"Acrolein addition +56" RELATED UniMod-description []
synonym	"Delta:H(4)C(3)O(1)" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "C 9 H 16 N 2 O 2"
xref	MassAvg: "184.24"
xref	MassMono: "184.121178"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00557 acrolein addition +56 ! acrolein addition +56
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1284. MOD:01284 acrolein addition +56 - site C

Table 1286. Term [MOD:01284]
id	MOD:01284
name	acrolein addition +56 - site C
def	"modification from UniMod Other -" [PubMed:10825247, PubMed:15541752, PubMed:9254591, UniMod:206#C]
synonym	"Acrolein addition +56" RELATED UniMod-description []
synonym	"Delta:H(4)C(3)O(1)" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "C 6 H 9 N 1 O 2 S 1"
xref	MassAvg: "159.20"
xref	MassMono: "159.035400"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00557 acrolein addition +56 ! acrolein addition +56
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1285. MOD:01285 6x(13)C,1x(15)N labeled L-leucine

Table 1287. Term [MOD:01285]
id	MOD:01285
name	6x(13)C,1x(15)N labeled L-leucine
def	"A protein modification that effectively converts an L-leucine residue to 6x(13)C,1x(15)N isotope labeled L-leucine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:695#L]
synonym	"13C(6) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "7.02"
xref	DiffFormula: "(12)C -6 (13)C 6 (14)N -1 (15)N 1"
xref	DiffMono: "7.017164"
xref	Formula: "(13)C 6 H 11 (15)N 1 O 1"
xref	MassAvg: "120.10"
xref	MassMono: "120.101228"
xref	Origin: "L"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue
is_a	MOD:01370 6x(13)C,1x(15)N labeled residue ! 6x(13)C,1x(15)N labeled residue

2.1286. MOD:01286 6x(13)C,1x(15)N labeled L-isoleucine

Table 1288. Term [MOD:01286]
id	MOD:01286
name	6x(13)C,1x(15)N labeled L-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to 6x(13)C,1x(15)N isotope labeled L-isoleucine." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:695#I]
synonym	"13C(6) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "7.02"
xref	DiffFormula: "(12)C -6 (13)C 6 (14)N -1 (15)N 1"
xref	DiffMono: "7.017164"
xref	Formula: "(13)C 6 H 11 (15)N 1 O 1"
xref	MassAvg: "120.10"
xref	MassMono: "120.101228"
xref	Origin: "I"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01370 6x(13)C,1x(15)N labeled residue ! 6x(13)C,1x(15)N labeled residue

2.1287. MOD:01287 Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form - site K

Table 1289. Term [MOD:01287]
id	MOD:01287
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form - site K
def	"modification from UniMod Isotopic label -" [PubMed:11857757, PubMed:15602776, UniMod:364#K]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form" RELATED UniMod-description []
synonym	"ICPL:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "111.04"
xref	DiffFormula: "(13)C 6 H 3 N 1 O 1"
xref	DiffMono: "111.041593"
xref	Formula: "C 6 (13)C 6 H 15 N 3 O 2"
xref	MassAvg: "239.14"
xref	MassMono: "239.136556"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00789 Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form ! Bruker Daltonics SERVA-ICPL™ quantification chemistry, heavy form
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1288. MOD:01288 acetaldehyde +28 - site H

Table 1290. Term [MOD:01288]
id	MOD:01288
name	acetaldehyde +28 - site H
def	"modification from UniMod Other -" [UniMod:255#H]
synonym	"Acetaldehyde +28" RELATED UniMod-description []
synonym	"Delta:H(4)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 11 N 3 O 1"
xref	MassAvg: "165.20"
xref	MassMono: "165.090212"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00578 acetaldehyde +28 ! acetaldehyde +28
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1289. MOD:01289 acetaldehyde +28 - site K

Table 1291. Term [MOD:01289]
id	MOD:01289
name	acetaldehyde +28 - site K
def	"modification from UniMod Other -" [UniMod:255#K]
synonym	"Acetaldehyde +28" RELATED UniMod-description []
synonym	"Delta:H(4)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 2 O 1"
xref	MassAvg: "156.23"
xref	MassMono: "156.126263"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00578 acetaldehyde +28 ! acetaldehyde +28
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1290. MOD:01290 dihydroxylated residue - site F

Table 1292. Term [MOD:01290]
id	MOD:01290
name	dihydroxylated residue - site F
def	"OBSOLETE because redundant and identical to MOD:00465. Remap to MOD:00465." [PubMed:11857757, PubMed:12175151, PubMed:12686488, PubMed:9252331, UniMod:425]
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 9 H 9 N 1 O 3"
xref	MassAvg: "179.17"
xref	MassMono: "179.058243"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1291. MOD:01291 dihydroxylated residue - site W

Table 1293. Term [MOD:01291]
id	MOD:01291
name	dihydroxylated residue - site W
def	"OBSOLETE because redundant and identical to MOD:00464. Remap to MOD:00464." [PubMed:12643539, PubMed:12686488, PubMed:6273432, PubMed:9252331, UniMod:425]
synonym	"dihydroxy" RELATED UniMod-description []
synonym	"Dioxidation" RELATED PSI-MS-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 11 H 10 N 2 O 3"
xref	MassAvg: "218.21"
xref	MassMono: "218.069142"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1292. MOD:01292 dimethylation of proline residue

Table 1294. Term [MOD:01292]
id	MOD:01292
name	dimethylation of proline residue
def	"OBSOLETE because redundant and identical to MOD:00075. Map to MOD:00075." [UniMod:529]
synonym	"Delta:H(5)C(2)" RELATED PSI-MS-label []
synonym	"Dimethylation of proline residue" RELATED UniMod-description []
xref	DiffAvg: "29.06"
xref	DiffFormula: "C 2 H 5"
xref	DiffMono: "29.039125"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1293. MOD:01293 1x(18)O labeled deamidated L-asparagine

Table 1295. Term [MOD:01293]
id	MOD:01293
name	1x(18)O labeled deamidated L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to L-aspartic acid with one (18)O." [OMSSA:139, PubMed:8382902, UniMod:366#N]
subset	PSI-MOD-slim
synonym	"Deamidated:18O(1)" RELATED PSI-MS-label []
synonym	"Deamidation in presence of O18" RELATED UniMod-description []
synonym	"oxy18" EXACT OMSSA-label []
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "C 4 H 5 N 1 (16)O 2 (18)O 1"
xref	MassAvg: "117.03"
xref	MassMono: "117.031189"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00852 1x(18)O labeled deamidated residue ! 1x(18)O labeled deamidated residue
relationship	derives_from MOD:00684 deamidated L-asparagine ! deamidated L-asparagine

2.1294. MOD:01294 deamidation in presence of O18 -site Q

Table 1296. Term [MOD:01294]
id	MOD:01294
name	deamidation in presence of O18 -site Q
def	"OBSOLETE identical and redundant with MOD:00791. Remap to MOD:00791." [PubMed:8382902]
synonym	"Deamidated:18O(1)" RELATED PSI-MS-label []
synonym	"Deamidation in presence of O18" RELATED UniMod-description []
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Q"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1295. MOD:01295 monosodium L-aspartate

Table 1297. Term [MOD:01295]
id	MOD:01295
name	monosodium L-aspartate
def	"A protein modification that effectively converts an L-aspartic acid residue to monosodium L-aspartate." [PubMed:12216740, UniMod:30#D]
subset	PSI-MOD-slim
synonym	"Cation:Na" RELATED PSI-MS-label []
synonym	"Na1Asp" EXACT PSI-MOD-label []
synonym	"Sodium adduct" RELATED UniMod-description []
xref	DiffAvg: "21.98"
xref	DiffFormula: "H -1 Na 1"
xref	DiffMono: "21.981944"
xref	Formula: "C 4 H 4 N 1 Na 1 O 3"
xref	MassAvg: "137.07"
xref	MassMono: "137.008887"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00423 monosodium salt ! monosodium salt
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1296. MOD:01296 monosodium L-glutamate

Table 1298. Term [MOD:01296]
id	MOD:01296
name	monosodium L-glutamate
def	"A protein modification that effectively converts an L-glutamic acid residue to monosodium L-glutamate." [PubMed:12216740, UniMod:30#E]
subset	PSI-MOD-slim
synonym	"Cation:Na" RELATED PSI-MS-label []
synonym	"MSG" EXACT PSI-MOD-alternate []
synonym	"Na1Glu" EXACT PSI-MOD-label []
synonym	"Sodium adduct" RELATED UniMod-description []
xref	DiffAvg: "21.98"
xref	DiffFormula: "H -1 Na 1"
xref	DiffMono: "21.981944"
xref	Formula: "C 5 H 6 N 1 Na 1 O 3"
xref	MassAvg: "151.10"
xref	MassMono: "151.024537"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00423 monosodium salt ! monosodium salt
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1297. MOD:01297 5x(13)C labeled L-proline

Table 1299. Term [MOD:01297]
id	MOD:01297
name	5x(13)C labeled L-proline
def	"A protein modification that effectively converts an L-proline residue to 5x(13)C labeled L-proline." [PubMed:12716131, UniMod:772#P]
comment	In PubMed:12716131, fully (13)C labeled proline apparently resulted from the catabolic conversion of (13)C labeled L-arginine during SILAC.
synonym	"13C(5) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)" RELATED PSI-MS-label []
xref	DiffAvg: "5.02"
xref	DiffFormula: "(12)C -5 (13)C 5"
xref	DiffMono: "5.016774"
xref	Formula: "(13)C 5 H 7 N 1 O 1"
xref	MassAvg: "102.07"
xref	MassMono: "102.069538"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01832 5x(13)C-labeled residue ! 5x(13)C-labeled residue

2.1298. MOD:01298 reduced cysteine 4-hydroxynonenal adduct

Table 1300. Term [MOD:01298]
id	MOD:01298
name	reduced cysteine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-cysteine residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4." [PubMed:11910026, PubMed:15133838, UniMod:335#C]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"HNE+Delta:H(2)" RELATED PSI-MS-label []
synonym	"reduced 4-Hydroxynonenal" RELATED UniMod-description []
xref	DiffAvg: "158.24"
xref	DiffFormula: "C 9 H 18 O 2"
xref	DiffMono: "158.130680"
xref	Formula: "C 12 H 23 N 1 O 3 S 1"
xref	MassAvg: "261.38"
xref	MassMono: "261.139865"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00642 reduced 4-hydroxynonenal adduct ! reduced 4-hydroxynonenal adduct
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
relationship	derives_from MOD:01237 cysteine 4-hydroxynonenal adduct ! cysteine 4-hydroxynonenal adduct

2.1299. MOD:01299 reduced lysine 4-hydroxynonenal adduct

Table 1301. Term [MOD:01299]
id	MOD:01299
name	reduced lysine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-histidine residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4." [PubMed:11910026, PubMed:12148805, PubMed:15133838, UniMod:335#K]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"HNE+Delta:H(2)" RELATED PSI-MS-label []
synonym	"reduced 4-Hydroxynonenal" RELATED UniMod-description []
xref	DiffAvg: "158.24"
xref	DiffFormula: "C 9 H 18 O 2"
xref	DiffMono: "158.130680"
xref	Formula: "C 15 H 30 N 2 O 3"
xref	MassAvg: "286.42"
xref	MassMono: "286.225643"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00642 reduced 4-hydroxynonenal adduct ! reduced 4-hydroxynonenal adduct
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
relationship	derives_from MOD:01238 lysine 4-hydroxynonenal adduct ! lysine 4-hydroxynonenal adduct

2.1300. MOD:01300 reduced histidine 4-hydroxynonenal adduct

Table 1302. Term [MOD:01300]
id	MOD:01300
name	reduced histidine 4-hydroxynonenal adduct
def	"A protein modification produced by formation of an adduct of an L-histidine residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4." [PubMed:11910026, PubMed:12148805, PubMed:15133838, UniMod:335#H]
comment	4-hydroxynonenal, a toxic lipid aldehyde, is a product of the hydroperoxide beta-cleavage degradation of omega-6 polyunsaturated fatty acids, such as arachidonic and linoleic acids [JSG].
synonym	"HNE+Delta:H(2)" RELATED PSI-MS-label []
synonym	"reduced 4-Hydroxynonenal" RELATED UniMod-description []
xref	DiffAvg: "158.24"
xref	DiffFormula: "C 9 H 18 O 2"
xref	DiffMono: "158.130680"
xref	Formula: "C 15 H 25 N 3 O 3"
xref	MassAvg: "295.38"
xref	MassMono: "295.189592"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00642 reduced 4-hydroxynonenal adduct ! reduced 4-hydroxynonenal adduct
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
relationship	derives_from MOD:01239 histidine 4-hydroxynonenal adduct ! histidine 4-hydroxynonenal adduct

2.1301. MOD:01301 methylamine Michael addition derivatized threonine

Table 1303. Term [MOD:01301]
id	MOD:01301
name	methylamine Michael addition derivatized threonine
def	"A protein modification that effectively converts an L-threonine residue to 2-amino-3-(methylamino)butanoic acid." [PubMed:11743741, UniMod:337#T]
comment	In PubMed:11743741 phosphothreonine is converted to dehydrobutyrine in base, then by Michael addition of methylamine to 2-amino-3-(methylamino)butanoic acid.
synonym	"Methylamine" RELATED PSI-MS-label []
synonym	"Michael addition with methylamine" RELATED UniMod-description []
xref	DiffAvg: "13.04"
xref	DiffFormula: "C 1 H 3 N 1 O -1"
xref	DiffMono: "13.031634"
xref	Formula: "C 5 H 10 N 2 O 1"
xref	MassAvg: "114.15"
xref	MassMono: "114.079313"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00643 methylamine Michael addition derivatized residue ! methylamine Michael addition derivatized residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1302. MOD:01302 methylamine Michael addition derivatized serine

Table 1304. Term [MOD:01302]
id	MOD:01302
name	methylamine Michael addition derivatized serine
def	"A protein modification that effectively converts an L-serine residue to 2-amino-3-(methylamino)propanoic acid." [PubMed:11743741, UniMod:337#S]
comment	In PubMed:11743741 phosphoserine is converted to dehydroalanine in base, then by Michael addition of methylamine to 2-amino-3-(methylamino)propanoic acid.
synonym	"Methylamine" RELATED PSI-MS-label []
synonym	"Michael addition with methylamine" RELATED UniMod-description []
xref	DiffAvg: "13.04"
xref	DiffFormula: "C 1 H 3 N 1 O -1"
xref	DiffMono: "13.031634"
xref	Formula: "C 4 H 8 N 2 O 1"
xref	MassAvg: "100.12"
xref	MassMono: "100.063663"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00643 methylamine Michael addition derivatized residue ! methylamine Michael addition derivatized residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1303. MOD:01303 N4-hexosaminylated asparagine

Table 1305. Term [MOD:01303]
id	MOD:01303
name	N4-hexosaminylated asparagine
def	"A protein modification that effectively converts an L-asparagine residue to an N4-hexosaminyl-L-asparagine." [PubMed:11467524, UniMod:454#N]
comment	The natural modifications are N4-(N-acetylamino)galactosyl-L-asparagine (MOD:00832) or N4-(N-acetylamino)glucosyl-L-asparagine (MOD:00831) [JSG].
synonym	"HexN" RELATED PSI-MS-label []
synonym	"Hexosamine" RELATED UniMod-description []
xref	DiffAvg: "161.16"
xref	DiffFormula: "C 6 H 11 N 1 O 4"
xref	DiffMono: "161.068808"
xref	Formula: "C 10 H 17 N 3 O 6"
xref	MassAvg: "275.26"
xref	MassMono: "275.111735"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00160 N4-glycosyl-L-asparagine ! N4-glycosyl-L-asparagine
is_a	MOD:00876 hexosaminylated residue ! hexosaminylated residue

2.1304. MOD:01304 N6-hexosaminylated lysine

Table 1306. Term [MOD:01304]
id	MOD:01304
name	N6-hexosaminylated lysine
def	"A protein modification that effectively converts an L-lysine residue to an N4-hexosaminyl-L-lysine, as a synthetic peptide protectting group." [UniMod:454#K]
synonym	"HexN" RELATED PSI-MS-label []
synonym	"Hexosamine" RELATED UniMod-description []
xref	DiffAvg: "161.16"
xref	DiffFormula: "C 6 H 11 N 1 O 4"
xref	DiffMono: "161.068808"
xref	Formula: "C 12 H 23 N 3 O 5"
xref	MassAvg: "289.33"
xref	MassMono: "289.163771"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00876 hexosaminylated residue ! hexosaminylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1305. MOD:01305 N1'-hexosaminylated tryptophan

Table 1307. Term [MOD:01305]
id	MOD:01305
name	N1'-hexosaminylated tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N1'-hexosaminyl-L-tryptophan." [UniMod:454#W]
comment	The natural modification is N1'-mannosyl-L-tryptophan (MOD:00165) [JSG].
synonym	"HexN" RELATED PSI-MS-label []
synonym	"Hexosamine" RELATED UniMod-description []
xref	DiffAvg: "161.16"
xref	DiffFormula: "C 6 H 11 N 1 O 4"
xref	DiffMono: "161.068808"
xref	Formula: "C 17 H 21 N 3 O 5"
xref	MassAvg: "347.37"
xref	MassMono: "347.148121"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00876 hexosaminylated residue ! hexosaminylated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1306. MOD:01306 O-hexosaminylated threonine

Table 1308. Term [MOD:01306]
id	MOD:01306
name	O-hexosaminylated threonine
def	"A protein modification that effectively converts an L-threonine residue to O-hexosaminyl-L-threonine." [UniMod:454#T]
comment	The natural modifications are O-(N-acetylaminogalactosyl)-L-threonine (MOD:00164) or O-(N-acetylaminoglucosyl)-L-threonine (MOD:00806) [JSG].
synonym	"HexN" RELATED PSI-MS-label []
synonym	"Hexosamine" RELATED UniMod-description []
xref	DiffAvg: "161.16"
xref	DiffFormula: "C 6 H 11 N 1 O 4"
xref	DiffMono: "161.068808"
xref	Formula: "C 10 H 18 N 2 O 6"
xref	MassAvg: "262.26"
xref	MassMono: "262.116486"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine
is_a	MOD:00876 hexosaminylated residue ! hexosaminylated residue

2.1307. MOD:01307 thiophosphate labeled with biotin-HPDP -site S

Table 1309. Term [MOD:01307]
id	MOD:01307
name	thiophosphate labeled with biotin-HPDP -site S
def	"modification from UniMod Chemical derivative -" [UniMod:332#S]
synonym	"Thiophos-S-S-biotin" RELATED PSI-MS-label []
synonym	"thiophosphate labeled with biotin-HPDP" RELATED UniMod-description []
xref	DiffAvg: "525.66"
xref	DiffFormula: "C 19 H 34 N 4 O 5 P 1 S 3"
xref	DiffMono: "525.142895"
xref	Formula: "C 22 H 39 N 5 O 7 P 1 S 3"
xref	MassAvg: "612.74"
xref	MassMono: "612.174923"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00639 thiophosphate labeled with biotin-HPDP ! thiophosphate labeled with biotin-HPDP
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1308. MOD:01308 thiophosphate labeled with biotin-HPDP -site T

Table 1310. Term [MOD:01308]
id	MOD:01308
name	thiophosphate labeled with biotin-HPDP -site T
def	"modification from UniMod Chemical derivative -" [UniMod:332#T]
synonym	"Thiophos-S-S-biotin" RELATED PSI-MS-label []
synonym	"thiophosphate labeled with biotin-HPDP" RELATED UniMod-description []
xref	DiffAvg: "525.66"
xref	DiffFormula: "C 19 H 34 N 4 O 5 P 1 S 3"
xref	DiffMono: "525.142895"
xref	Formula: "C 23 H 41 N 5 O 7 P 1 S 3"
xref	MassAvg: "626.76"
xref	MassMono: "626.190573"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00639 thiophosphate labeled with biotin-HPDP ! thiophosphate labeled with biotin-HPDP
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1309. MOD:01309 thiophosphate labeled with biotin-HPDP - site Y

Table 1311. Term [MOD:01309]
id	MOD:01309
name	thiophosphate labeled with biotin-HPDP - site Y
def	"modification from UniMod Chemical derivative - " [UniMod:332#Y]
synonym	"Thiophos-S-S-biotin" RELATED PSI-MS-label []
synonym	"thiophosphate labeled with biotin-HPDP" RELATED UniMod-description []
xref	DiffAvg: "525.66"
xref	DiffFormula: "C 19 H 34 N 4 O 5 P 1 S 3"
xref	DiffMono: "525.142895"
xref	Formula: "C 28 H 43 N 5 O 7 P 1 S 3"
xref	MassAvg: "688.83"
xref	MassMono: "688.206223"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00639 thiophosphate labeled with biotin-HPDP ! thiophosphate labeled with biotin-HPDP
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1310. MOD:01310 quaternary amine labeling reagent light form N6-L-lysine

Table 1312. Term [MOD:01310]
id	MOD:01310
name	quaternary amine labeling reagent light form N6-L-lysine
def	"A protein modification that effectively replaces a lysine N6-hydrogen with a quaternary amine reagent light form group." [PubMed:11857757, UniMod:60#K]
synonym	"GIST-Quat" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent light form (N-term & K)" RELATED UniMod-description []
xref	DiffAvg: "59.07"
xref	DiffFormula: "C 3 (1)H 9 N 1"
xref	DiffMono: "59.073499"
xref	Formula: "C 9 (1)H 21 N 3 O 1"
xref	MassAvg: "187.17"
xref	MassMono: "187.168462"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1311. MOD:01311 quaternary amine labeling reagent heavy form (+3amu) N6-L-lysine

Table 1313. Term [MOD:01311]
id	MOD:01311
name	quaternary amine labeling reagent heavy form (+3amu) N6-L-lysine
def	"A protein modification that effectively replaces a lysine N6-hydrogen with a quaternary amine reagent heavy (+3amu) form group." [PubMed:11698400, PubMed:11857757, PubMed:11914093, UniMod:61#K]
synonym	"GIST-Quat:2H(3)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy (+3amu) form, N-term & K" RELATED UniMod-description []
xref	DiffAvg: "62.09"
xref	DiffFormula: "C 3 (1)H 6 (2)H 3 N 1"
xref	DiffMono: "62.092330"
xref	Formula: "C 9 (1)H 18 (2)H 3 N 3 O 1"
xref	MassAvg: "190.19"
xref	MassMono: "190.187293"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1312. MOD:01312 quaternary amine labeling reagent heavy form (+6amu) N6-L-lysine

Table 1314. Term [MOD:01312]
id	MOD:01312
name	quaternary amine labeling reagent heavy form (+6amu) N6-L-lysine
def	"A protein modification that effectively replaces a lysine N6-hydrogen with a quaternary amine reagent heavy (+6amu) form group." [PubMed:11857757, UniMod:62#K]
comment	Apparently incorrect parent [JSG].
synonym	"GIST-Quat:2H(6)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy form (+6amu), N-term & K" RELATED UniMod-description []
xref	DiffAvg: "65.11"
xref	DiffFormula: "C 3 (1)H 3 (2)H 6 N 1"
xref	DiffMono: "65.111160"
xref	Formula: "C 9 (1)H 15 (2)H 6 N 3 O 1"
xref	MassAvg: "193.21"
xref	MassMono: "193.206123"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1313. MOD:01313 quaternary amine labeling reagent heavy form (+9amu) N6-L-lysine

Table 1315. Term [MOD:01313]
id	MOD:01313
name	quaternary amine labeling reagent heavy form (+9amu) N6-L-lysine
def	"A protein modification that effectively replaces a lysine N6-hydrogen with a quaternary amine reagent heavy (+9amu) form group." [PubMed:11857757, UniMod:63#K]
synonym	"GIST-Quat:2H(9)" RELATED PSI-MS-label []
synonym	"Quaternary amine labeling reagent heavy form (+9amu), N-term & K" RELATED UniMod-description []
xref	DiffAvg: "68.13"
xref	DiffFormula: "C 3 (2)H 9 N 1"
xref	DiffMono: "68.129990"
xref	Formula: "C 9 (1)H 12 (2)H 9 N 3 O 1"
xref	MassAvg: "196.22"
xref	MassMono: "196.224953"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1314. MOD:01314 4x(1)H,4x(12)C-labeled N6-succinyl-L-lysine

Table 1316. Term [MOD:01314]
id	MOD:01314
name	4x(1)H,4x(12)C-labeled N6-succinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4x(1)H,4x(12)C-labeled N6-succinyl-L-lysine." [PubMed:11857757, PubMed:12175151, PubMed:12716131, UniMod:64#K]
synonym	"Succinic anhydride labeling reagent light form (K)" RELATED UniMod-description []
synonym	"Succinyl" RELATED PSI-MS-label []
xref	DiffAvg: "100.02"
xref	DiffFormula: "(12)C 4 (1)H 4 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "(12)C 10 H 16 N 2 O 4"
xref	MassAvg: "228.11"
xref	MassMono: "228.111007"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01819 N6-succinyl-L-lysine ! N6-succinyl-L-lysine

2.1315. MOD:01315 4x(2)H labeled N6-succinyl-L-lysine

Table 1317. Term [MOD:01315]
id	MOD:01315
name	4x(2)H labeled N6-succinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4x(2)H-labeled N6-succinyl-L-lysine." [PubMed:11344537, PubMed:11857757, PubMed:12175151, PubMed:15189151, UniMod:65#K]
synonym	"Succinic anhydride labeling reagent, heavy form (+4amu, 4H2), N-term & K" RELATED UniMod-description []
synonym	"Succinyl:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "104.04"
xref	DiffFormula: "C 4 (2)H 4 O 3"
xref	DiffMono: "104.041151"
xref	Formula: "C 10 (1)H 12 (2)H 4 N 2 O 4"
xref	MassAvg: "232.14"
xref	MassMono: "232.136114"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01819 N6-succinyl-L-lysine ! N6-succinyl-L-lysine

2.1316. MOD:01316 4x(13)C labeled N6-succinyl-L-lysine

Table 1318. Term [MOD:01316]
id	MOD:01316
name	4x(13)C labeled N6-succinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 4x(13)C labeled N6-succinyl-L-lysine." [PubMed:11344537, PubMed:11857757, PubMed:12175151, PubMed:15189151, UniMod:66#K]
synonym	"Succinic anhydride labeling reagent, heavy form (+4amu, 4C13), K" RELATED UniMod-description []
synonym	"Succinyl:13C(4)" RELATED PSI-MS-label []
xref	DiffAvg: "104.03"
xref	DiffFormula: "(13)C 4 H 4 O 3"
xref	DiffMono: "104.029463"
xref	Formula: "(12)C 6 (13)C 4 H 16 N 2 O 4"
xref	MassAvg: "232.12"
xref	MassMono: "232.124426"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01819 N6-succinyl-L-lysine ! N6-succinyl-L-lysine

2.1317. MOD:01317 phosphorylation to amine thiol - site T

Table 1319. Term [MOD:01317]
id	MOD:01317
name	phosphorylation to amine thiol - site T
def	"modification from UniMod Chemical derivative -" [PubMed:12216740, UniMod:178#T]
synonym	"DAET" RELATED PSI-MS-label []
synonym	"phosphorylation to amine thiol" RELATED UniMod-description []
xref	DiffAvg: "87.18"
xref	DiffFormula: "C 4 H 9 N 1 O -1 S 1"
xref	DiffMono: "87.050656"
xref	Formula: "C 8 H 16 N 2 O 1 S 1"
xref	MassAvg: "188.29"
xref	MassMono: "188.098334"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00535 phosphorylation to amine thiol ! phosphorylation to amine thiol
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1318. MOD:01318 phosphorylation to amine thiol - site S

Table 1320. Term [MOD:01318]
id	MOD:01318
name	phosphorylation to amine thiol - site S
def	"modification from UniMod Chemical derivative -" [PubMed:11510821, PubMed:12216740, PubMed:12422359, UniMod:178#S]
synonym	"DAET" RELATED PSI-MS-label []
synonym	"phosphorylation to amine thiol" RELATED UniMod-description []
xref	DiffAvg: "87.18"
xref	DiffFormula: "C 4 H 9 N 1 O -1 S 1"
xref	DiffMono: "87.050656"
xref	Formula: "C 7 H 14 N 2 O 1 S 1"
xref	MassAvg: "174.26"
xref	MassMono: "174.082684"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00535 phosphorylation to amine thiol ! phosphorylation to amine thiol
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1319. MOD:01319 Michael addition of BHT quinone methide to histidine

Table 1321. Term [MOD:01319]
id	MOD:01319
name	Michael addition of BHT quinone methide to histidine
def	"modification from UniMod Other" [PubMed:11510821, PubMed:12422359, PubMed:9448752, UniMod:176#H]
comment	Secondary adduct, much less common than cysteine. [UniMod]
synonym	"BHT" RELATED PSI-MS-label []
synonym	"Michael addition of BHT quinone methide to Cysteine and Lysine" RELATED UniMod-description []
xref	DiffAvg: "218.34"
xref	DiffFormula: "C 15 H 22 O 1"
xref	DiffMono: "218.167065"
xref	Formula: "C 21 H 29 N 3 O 2"
xref	MassAvg: "355.48"
xref	MassMono: "355.225977"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00534 Michael addition of BHT quinone methide to cysteine and lysine ! Michael addition of BHT quinone methide to cysteine and lysine
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1320. MOD:01320 Michael addition of BHT quinone methide to lysine

Table 1322. Term [MOD:01320]
id	MOD:01320
name	Michael addition of BHT quinone methide to lysine
def	"modification from UniMod Other" [PubMed:16078144, PubMed:9448752, UniMod:176#K]
comment	Secondary adduct, much less common than cysteine. [UniMod]
synonym	"BHT" RELATED PSI-MS-label []
synonym	"Michael addition of BHT quinone methide to Cysteine and Lysine" RELATED UniMod-description []
xref	DiffAvg: "218.34"
xref	DiffFormula: "C 15 H 22 O 1"
xref	DiffMono: "218.167065"
xref	Formula: "C 21 H 34 N 2 O 2"
xref	MassAvg: "346.51"
xref	MassMono: "346.262028"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00534 Michael addition of BHT quinone methide to cysteine and lysine ! Michael addition of BHT quinone methide to cysteine and lysine
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1321. MOD:01321 Michael addition of BHT quinone methide to cysteine

Table 1323. Term [MOD:01321]
id	MOD:01321
name	Michael addition of BHT quinone methide to cysteine
def	"modification from UniMod Other" [PubMed:11510821, PubMed:12422359, PubMed:9448752, UniMod:176#C]
comment	Primary adduct formed. [UniMod]
synonym	"BHT" RELATED PSI-MS-label []
synonym	"Michael addition of BHT quinone methide to Cysteine and Lysine" RELATED UniMod-description []
xref	DiffAvg: "218.34"
xref	DiffFormula: "C 15 H 22 O 1"
xref	DiffMono: "218.167065"
xref	Formula: "C 18 H 27 N 1 O 2 S 1"
xref	MassAvg: "321.48"
xref	MassMono: "321.176250"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00534 Michael addition of BHT quinone methide to cysteine and lysine ! Michael addition of BHT quinone methide to cysteine and lysine
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1322. MOD:01322 propionaldehyde +40 - site K

Table 1324. Term [MOD:01322]
id	MOD:01322
name	propionaldehyde +40 - site K
def	"modification from UniMod Other -" [PubMed:15549660, UniMod:256#K]
synonym	"Delta:H(4)C(3)" RELATED PSI-MS-label []
synonym	"Propionaldehyde +40" RELATED UniMod-description []
xref	DiffAvg: "40.06"
xref	DiffFormula: "C 3 H 4"
xref	DiffMono: "40.031300"
xref	Formula: "C 9 H 16 N 2 O 1"
xref	MassAvg: "168.24"
xref	MassMono: "168.126263"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00579 propionaldehyde +40 ! propionaldehyde +40
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1323. MOD:01323 propionaldehyde +40 - site H

Table 1325. Term [MOD:01323]
id	MOD:01323
name	propionaldehyde +40 - site H
def	"modification from UniMod Other -" [UniMod:256#H]
synonym	"Delta:H(4)C(3)" RELATED PSI-MS-label []
synonym	"Propionaldehyde +40" RELATED UniMod-description []
xref	DiffAvg: "40.06"
xref	DiffFormula: "C 3 H 4"
xref	DiffMono: "40.031300"
xref	Formula: "C 9 H 11 N 3 O 1"
xref	MassAvg: "177.21"
xref	MassMono: "177.090212"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00579 propionaldehyde +40 ! propionaldehyde +40
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1324. MOD:01324 acetaldehyde +26 - site H

Table 1326. Term [MOD:01324]
id	MOD:01324
name	acetaldehyde +26 - site H
def	"modification from UniMod Other -" [PubMed:7744761, UniMod:254#H]
synonym	"Acetaldehyde +26" RELATED UniMod-description []
synonym	"Delta:H(2)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "26.04"
xref	DiffFormula: "C 2 H 2"
xref	DiffMono: "26.015650"
xref	Formula: "C 8 H 9 N 3 O 1"
xref	MassAvg: "163.18"
xref	MassMono: "163.074562"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00577 acetaldehyde +26 ! acetaldehyde +26
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1325. MOD:01325 acetaldehyde +26 - site K

Table 1327. Term [MOD:01325]
id	MOD:01325
name	acetaldehyde +26 - site K
def	"modification from UniMod Other -" [PubMed:7744761, UniMod:254#K]
synonym	"Acetaldehyde +26" RELATED UniMod-description []
synonym	"Delta:H(2)C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "26.04"
xref	DiffFormula: "C 2 H 2"
xref	DiffMono: "26.015650"
xref	Formula: "C 8 H 14 N 2 O 1"
xref	MassAvg: "154.21"
xref	MassMono: "154.110613"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00577 acetaldehyde +26 ! acetaldehyde +26
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1326. MOD:01326 9x(13)C labeled L-tyrosine

Table 1328. Term [MOD:01326]
id	MOD:01326
name	9x(13)C labeled L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 9x(13)C labeled L-tyrosine." [PubMed:11510821, PubMed:12422359, PubMed:12716131, UniMod:184#Y]
synonym	"13C(9) Silac label" RELATED UniMod-description []
synonym	"Label:13C(9)" RELATED PSI-MS-label []
xref	DiffAvg: "9.03"
xref	DiffFormula: "(12)C -9 (13)C 9"
xref	DiffMono: "9.030194"
xref	Formula: "(13)C 9 H 9 N 1 O 2"
xref	MassAvg: "172.09"
xref	MassMono: "172.093522"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00540 9x(13)C labeled residue ! 9x(13)C labeled residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1327. MOD:01327 9x(13)C labeled L-phenylalanine

Table 1329. Term [MOD:01327]
id	MOD:01327
name	9x(13)C labeled L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to 9x(13)C labeled L-phenylalanine." [PubMed:12716131, UniMod:184#F]
synonym	"13C(9) Silac label" RELATED UniMod-description []
synonym	"Label:13C(9)" RELATED PSI-MS-label []
xref	DiffAvg: "9.03"
xref	DiffFormula: "(12)C -9 (13)C 9"
xref	DiffMono: "9.030194"
xref	Formula: "(13)C 9 H 9 N 1 O 1"
xref	MassAvg: "156.10"
xref	MassMono: "156.098607"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00540 9x(13)C labeled residue ! 9x(13)C labeled residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.1328. MOD:01328 iodoacetic acid - site W

Table 1330. Term [MOD:01328]
id	MOD:01328
name	iodoacetic acid - site W
def	"modification from UniMod Chemical derivative - hydroxylethanone" [PubMed:17525468, UniMod:6#W]
comment	There is no citation for this UniMod entry. Iodoacetic acid derivatization of tryptophan is not mentioned in the citation [JSG].
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "C 13 H 12 N 2 O 3"
xref	MassAvg: "244.25"
xref	MassMono: "244.084792"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1329. MOD:01329 iodoacetic acid - site C

Table 1331. Term [MOD:01329]
id	MOD:01329
name	iodoacetic acid - site C
def	"OBSOLETE because duplicate and redundant with MOD:01061. Remap to MOD:01061" [DeltaMass:197]
comment	Modification from UniMod Chemical derivative, UniMod:6 site C
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1330. MOD:01330 iodoacetic acid -site K

Table 1332. Term [MOD:01330]
id	MOD:01330
name	iodoacetic acid -site K
def	"OBSOLETE because identical with MOD:01094. Remap to MOD:01094" [PubMed:18688235]
comment	a modification from UniMod:6
synonym	"Carboxymethyl" RELATED PSI-MS-label []
synonym	"Iodoacetic acid derivative" RELATED UniMod-description []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 O 2"
xref	DiffMono: "58.005479"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1331. MOD:01331 6x(13)C labeled L-arginine

Table 1333. Term [MOD:01331]
id	MOD:01331
name	6x(13)C labeled L-arginine
def	"A protein modification that effectively converts an L-arginine residue to 6x(13)C labeled L-arginine." [OMSSA:136, PubMed:12716131, UniMod:188#R]
subset	PSI-MOD-slim
synonym	"13C(6) Silac label" RELATED UniMod-description []
synonym	"arg-13c6" EXACT OMSSA-label []
synonym	"Label:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "6.02"
xref	DiffFormula: "(12)C -6 (13)C 6"
xref	DiffMono: "6.020129"
xref	Formula: "(13)C 6 H 12 N 4 O 1"
xref	MassAvg: "162.12"
xref	MassMono: "162.121240"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00544 6x(13)C labeled residue ! 6x(13)C labeled residue

2.1332. MOD:01332 6x(13)C labeled L-leucine

Table 1334. Term [MOD:01332]
id	MOD:01332
name	6x(13)C labeled L-leucine
def	"A protein modification that effectively converts an L-leucine residue to 6x(13)C labeled L-leucine." [PubMed:12716131, UniMod:188#L]
subset	PSI-MOD-slim
synonym	"13C(6) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "6.02"
xref	DiffFormula: "(12)C -6 (13)C 6"
xref	DiffMono: "6.020129"
xref	Formula: "(13)C 6 H 11 N 1 O 1"
xref	MassAvg: "119.10"
xref	MassMono: "119.104193"
xref	Origin: "L"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00544 6x(13)C labeled residue ! 6x(13)C labeled residue

2.1333. MOD:01333 6x(13)C labeled L-isoleucine

Table 1335. Term [MOD:01333]
id	MOD:01333
name	6x(13)C labeled L-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to 6x(13)C labeled L-isoleucine." [PubMed:12716131, PubMed:12766232, UniMod:188#I]
subset	PSI-MOD-slim
synonym	"13C(6) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "6.02"
xref	DiffFormula: "(12)C -6 (13)C 6"
xref	DiffMono: "6.020129"
xref	Formula: "(13)C 6 H 11 N 1 O 1"
xref	MassAvg: "119.10"
xref	MassMono: "119.104193"
xref	Origin: "I"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00544 6x(13)C labeled residue ! 6x(13)C labeled residue

2.1334. MOD:01334 6x(13)C labeled L-lysine

Table 1336. Term [MOD:01334]
id	MOD:01334
name	6x(13)C labeled L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 6x(13)C labeled L-lysine." [OMSSA:138, PubMed:11857757, PubMed:11999733, PubMed:12175151, PubMed:12716131, UniMod:188#K]
subset	PSI-MOD-slim
synonym	"13C(6) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)" RELATED PSI-MS-label []
synonym	"lys-13c6" EXACT OMSSA-label []
xref	DiffAvg: "6.02"
xref	DiffFormula: "(12)C -6 (13)C 6"
xref	DiffMono: "6.020129"
xref	Formula: "(13)C 6 H 12 N 2 O 1"
xref	MassAvg: "134.12"
xref	MassMono: "134.115092"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00544 6x(13)C labeled residue ! 6x(13)C labeled residue

2.1335. MOD:01335 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized lysine

Table 1337. Term [MOD:01335]
id	MOD:01335
name	6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized lysine
def	"modification from UniMod Chemical derivative -" [PubMed:11467524, PubMed:16526082, UniMod:464#K]
synonym	"4-sulfophenyl isothiocyanate (Heavy C13)" RELATED UniMod-description []
synonym	"SPITC:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "220.99"
xref	DiffFormula: "(12)C 1 (13)C 6 H 5 N 1 O 3 S 2"
xref	DiffMono: "220.991214"
xref	Formula: "(12)C 7 (13)C 6 H 17 N 3 O 4 S 2"
xref	MassAvg: "349.09"
xref	MassMono: "349.086177"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00880 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue ! 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1336. MOD:01336 deamidation followed by a methylation -site Q

Table 1338. Term [MOD:01336]
id	MOD:01336
name	deamidation followed by a methylation -site Q
def	"OBSOLETE - identical and redundant with MOD:00657. Remap to MOD:00657." [PubMed:18688235]
comment	Modification from UniMod Post-translational - UniMod:528.
synonym	"Deamidation followed by a methylation" RELATED UniMod-description []
synonym	"Methyl+Deamidated" RELATED PSI-MS-label []
xref	DiffAvg: "15.01"
xref	DiffFormula: "C 1 H 1 N -1 O 1"
xref	DiffMono: "14.999666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1337. MOD:01337 deamidated 4-methyl esterified asparagine

Table 1339. Term [MOD:01337]
id	MOD:01337
name	deamidated 4-methyl esterified asparagine
def	"A protein modification that effectively converts an L-asparagine residue to L-aspartate 4-methyl ester." [UniMod:528#N]
comment	The deamidation and methylation of L-asparagine has not been reported as a natural modification. It is extremely unlikely that eukaryotes produce this modification, because a natural process that would form L-aspartic acid 4-methyl ester from either L-aspartic acid or L-asparagine would interfere with the D-aspartyl peptide repair mechanism [JSG].
synonym	"Deamidation followed by a methylation" RELATED UniMod-description []
synonym	"Methyl+Deamidated" RELATED PSI-MS-label []
xref	DiffAvg: "15.01"
xref	DiffFormula: "C 1 H 1 N -1 O 1"
xref	DiffMono: "14.999666"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "N"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01181 L-aspartic acid 4-methyl ester ! L-aspartic acid 4-methyl ester
is_a	MOD:01369 deamidated and methyl esterified residue ! deamidated and methyl esterified residue

2.1338. MOD:01338 N6-ethyl-L-lysine

Table 1340. Term [MOD:01338]
id	MOD:01338
name	N6-ethyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-ethyl-L-lysine." [PubMed:9629898, UniMod:280#K]
comment	The UniMod citation refers to the formation of glutamate ethyl ester and not to either lysine or N-terminal alkylation [JSG].
synonym	"Ethyl" RELATED PSI-MS-label []
synonym	"Ethylation" RELATED UniMod-description []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 2 O 1"
xref	MassAvg: "156.23"
xref	MassMono: "156.126263"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01339 ethylated residue ! ethylated residue

2.1339. MOD:01339 ethylated residue

Table 1341. Term [MOD:01339]
id	MOD:01339
name	ethylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an ethyl group." [PubMed:9629898, UniMod:280]
comment	From DeltaMass: Average Mass: 28 with no citation. The UniMod citation refers to the formation of glutamate ethyl ester and not to either lysine or N-terminal alkylation [JSG].
synonym	"Ethyl" RELATED PSI-MS-label []
synonym	"Ethylation" RELATED UniMod-description []
synonym	"EtRes" EXACT PSI-MOD-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00001 alkylated residue ! alkylated residue

2.1340. MOD:01340 ESP-Tag heavy d10 - site K

Table 1342. Term [MOD:01340]
id	MOD:01340
name	ESP-Tag heavy d10 - site K
def	"modification from UniMod Isotopic label -" [PubMed:11078590, PubMed:11085420, PubMed:11821862, UniMod:91#K]
synonym	"ESP-Tag heavy d10" RELATED UniMod-description []
synonym	"ESP:2H(10)" RELATED PSI-MS-label []
xref	DiffAvg: "348.24"
xref	DiffFormula: "C 16 (1)H 16 (2)H 10 N 4 O 2 S 1"
xref	DiffMono: "348.240415"
xref	Formula: "C 22 (1)H 28 (2)H 10 N 6 O 3 S 1"
xref	MassAvg: "476.34"
xref	MassMono: "476.335378"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00469 ESP-Tag heavy d10 ! ESP-Tag heavy d10
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1341. MOD:01341 ESP-Tag light d0 - site K

Table 1343. Term [MOD:01341]
id	MOD:01341
name	ESP-Tag light d0 - site K
def	"modification from UniMod Isotopic label -" [UniMod:90#K]
synonym	"ESP" RELATED PSI-MS-label []
synonym	"ESP-Tag light d0" RELATED UniMod-description []
xref	DiffAvg: "338.47"
xref	DiffFormula: "C 16 H 26 N 4 O 2 S 1"
xref	DiffMono: "338.177647"
xref	Formula: "C 22 H 38 N 6 O 3 S 1"
xref	MassAvg: "466.64"
xref	MassMono: "466.272610"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00468 ESP-Tag light d0 ! ESP-Tag light d0
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1342. MOD:01342 selenium substitution for sulfur - site M

Table 1344. Term [MOD:01342]
id	MOD:01342
name	selenium substitution for sulfur - site M
def	"OBSOLETE because redundant and identical to MOD:00530. Remap to MOD:00530." [PubMed:12148805, UniMod:162]
synonym	"Delta:S(-1)Se(1)" RELATED PSI-MS-label []
synonym	"Selenium replaces sulphur" RELATED UniMod-description []
xref	DiffAvg: "46.91"
xref	DiffFormula: "S -1 Se 1"
xref	DiffMono: "47.944450"
xref	Formula: "C 5 H 9 N 1 O 1 S 0 Se 1"
xref	MassAvg: "178.10"
xref	MassMono: "178.984935"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1343. MOD:01343 selenium substitution for sulfur - site C

Table 1345. Term [MOD:01343]
id	MOD:01343
name	selenium substitution for sulfur - site C
def	"OBSOLETE because redundant and identical to MOD:00686. Remap to MOD:00686." [PubMed:12148805, UniMod:162]
synonym	"Delta:S(-1)Se(1)" RELATED PSI-MS-label []
synonym	"Selenium replaces sulphur" RELATED UniMod-description []
xref	DiffAvg: "46.91"
xref	DiffFormula: "S -1 Se 1"
xref	DiffMono: "47.944450"
xref	Formula: "C 3 H 5 N 1 O 1 S 0 Se 1"
xref	MassAvg: "150.05"
xref	MassMono: "150.953635"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1344. MOD:01344 dehydrogenated residue - site S

Table 1346. Term [MOD:01344]
id	MOD:01344
name	dehydrogenated residue - site S
def	"OBSOLETE because redundant and identical with MOD:00835. Remap to MOD:00835." [PubMed:9252331, PubMed:9276974, UniMod:401]
synonym	"2-amino-3-oxo-butanoic_acid" RELATED UniMod-description []
synonym	"Didehydro" RELATED PSI-MS-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "H -2"
xref	DiffMono: "-2.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1345. MOD:01345 2-amino-3-oxobutanoic acid

Table 1347. Term [MOD:01345]
id	MOD:01345
name	2-amino-3-oxobutanoic acid
def	"A protein modification that effectively converts an L-threonine residue to 2-amino-3-oxobutanoic acid." [OMSSA:23, PubMed:12716131, PubMed:9252331, UniMod:401#T]
comment	There is no citation for this modification in the UniMod entry. Although mentioned in PubMed:9252331, there is no citation for it there [JSG].
synonym	"2-amino-3-ketobutyric acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-3-oxo-butanoic_acid" RELATED UniMod-description []
synonym	"3-ketobutyrine" EXACT PSI-MOD-alternate []
synonym	"Didehydro" RELATED PSI-MS-label []
synonym	"twoamino3oxobutanoicacid" EXACT OMSSA-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "H -2"
xref	DiffMono: "-2.015650"
xref	Formula: "C 4 H 5 N 1 O 2"
xref	MassAvg: "99.09"
xref	MassMono: "99.032028"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1346. MOD:01346 N4-hexosylated asparagine

Table 1348. Term [MOD:01346]
id	MOD:01346
name	N4-hexosylated asparagine
def	"A protein modification that effectively converts an L-asparagine residue to an N4-hexosyl-L-asparagine." [PubMed:11112526, PubMed:11567090, PubMed:15279557, PubMed:6540775, UniMod:41#N]
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 10 H 16 N 2 O 7"
xref	MassAvg: "276.25"
xref	MassMono: "276.095751"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00160 N4-glycosyl-L-asparagine ! N4-glycosyl-L-asparagine
is_a	MOD:00434 hexosylated residue ! hexosylated residue

2.1347. MOD:01347 hexose glycated L-lysine

Table 1349. Term [MOD:01347]
id	MOD:01347
name	hexose glycated L-lysine
def	"A modification produced in a non-enzymatic reaction between a carbohydrate carbonyl group (C1 of aldohexose or C2 of fructose) and an L-lysine residue to form a Schiff-base or an Amadori ketosamine lysine adduct." [DeltaMass:0, PubMed:15279557, UniMod:41#K]
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 12 H 22 N 2 O 6"
xref	MassAvg: "290.32"
xref	MassMono: "290.147786"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00767 glycated residue ! glycated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1348. MOD:01348 O-hexosylated threonine

Table 1350. Term [MOD:01348]
id	MOD:01348
name	O-hexosylated threonine
def	"A protein modification that effectively converts an L-threonine residue to an O-hexosyl-L-threonine." [PubMed:15279557, PubMed:8597590, UniMod:41#T]
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
xref	DiffAvg: "162.14"
xref	DiffFormula: "C 6 H 10 O 5"
xref	DiffMono: "162.052823"
xref	Formula: "C 10 H 17 N 1 O 7"
xref	MassAvg: "263.25"
xref	MassMono: "263.100502"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine
is_a	MOD:00434 hexosylated residue ! hexosylated residue

2.1349. MOD:01349 hydrolyzed N-ethylmaleimide cysteine adduct

Table 1351. Term [MOD:01349]
id	MOD:01349
name	hydrolyzed N-ethylmaleimide cysteine adduct
def	"modification from UniMod Chemical derivative -" [UniMod:320#C]
comment	Hydolyzed N-ethylmaeimide adduct, a mixture of isobaric 2- and 3-(S-cysteinyl)-4-(ethylamino)-4-oxobutanoic acid [JSG].
synonym	"Nethylmaleimide+water" RELATED PSI-MS-label []
synonym	"Nethylmaleimidehydrolysis" RELATED UniMod-description []
xref	DiffAvg: "143.14"
xref	DiffFormula: "C 6 H 9 N 1 O 3"
xref	DiffMono: "143.058243"
xref	Formula: "C 9 H 14 N 2 O 4 S 1"
xref	MassAvg: "246.28"
xref	MassMono: "246.067428"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00631 hydrolyzed N-ethylmaleimide adduct ! hydrolyzed N-ethylmaleimide adduct
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1350. MOD:01350 hydrolyzed N-ethylmaleimide lysine adduct

Table 1352. Term [MOD:01350]
id	MOD:01350
name	hydrolyzed N-ethylmaleimide lysine adduct
def	"modification from UniMod Chemical derivative -" [UniMod:320#K]
comment	Hydolyzed N-ethylmaeimide adduct, a mixture of isobaric 2- and 3-(N6-lysyl)-4-(ethylamino)-4-oxobutanoic acid [JSG].
synonym	"Nethylmaleimide+water" RELATED PSI-MS-label []
synonym	"Nethylmaleimidehydrolysis" RELATED UniMod-description []
xref	DiffAvg: "143.14"
xref	DiffFormula: "C 6 H 9 N 1 O 3"
xref	DiffMono: "143.058243"
xref	Formula: "C 12 H 21 N 3 O 4"
xref	MassAvg: "271.32"
xref	MassMono: "271.153206"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00631 hydrolyzed N-ethylmaleimide adduct ! hydrolyzed N-ethylmaleimide adduct

2.1351. MOD:01351 nitrated L-tryptophan

Table 1353. Term [MOD:01351]
id	MOD:01351
name	nitrated L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to a nitrated L-tryptophan." [OMSSA:85, PubMed:8839040, PubMed:9252331, UniMod:354#W]
comment	One or more isobaric isomers are produced by nitration with peroxynitrite reagent [JSG].
synonym	"Nitro" RELATED PSI-MS-label []
synonym	"nitrow" EXACT OMSSA-label []
synonym	"Oxidation to nitro" RELATED UniMod-description []
xref	DiffAvg: "45.00"
xref	DiffFormula: "H -1 N 1 O 2"
xref	DiffMono: "44.985078"
xref	Formula: "C 11 H 9 N 3 O 3"
xref	MassAvg: "231.21"
xref	MassMono: "231.064391"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00461 nitrosylation ! nitrosylation
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1352. MOD:01352 nitrated L-tyrosine

Table 1354. Term [MOD:01352]
id	MOD:01352
name	nitrated L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to a nitrated L-tyrosine." [OMSSA:86, PubMed:14678012, PubMed:8839040, PubMed:9252331, UniMod:354#Y]
comment	One or more isobaric isomers are produced by nitration with peroxynitrite reagent [JSG].
subset	PSI-MOD-slim
synonym	"Nitro" RELATED PSI-MS-label []
synonym	"nitroy" EXACT OMSSA-label []
synonym	"Oxidation to nitro" RELATED UniMod-description []
xref	DiffAvg: "45.00"
xref	DiffFormula: "H -1 N 1 O 2"
xref	DiffMono: "44.985078"
xref	Formula: "C 9 H 8 N 2 O 4"
xref	MassAvg: "208.17"
xref	MassMono: "208.048407"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00461 nitrosylation ! nitrosylation
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1353. MOD:01353 amidination of lysines or N-terminal amines with methyl acetimidate - site K

Table 1355. Term [MOD:01353]
id	MOD:01353
name	amidination of lysines or N-terminal amines with methyl acetimidate - site K
def	"modification from UniMod Chemical derivative -" [PubMed:12643539, PubMed:15602776, PubMed:6273432, UniMod:141#K]
synonym	"amidination of lysines or N-terminal amines with methyl acetimidate" RELATED UniMod-description []
synonym	"Amidine" RELATED PSI-MS-label []
xref	DiffAvg: "41.05"
xref	DiffFormula: "C 2 H 3 N 1"
xref	DiffMono: "41.026549"
xref	Formula: "C 8 H 15 N 3 O 1"
xref	MassAvg: "169.23"
xref	MassMono: "169.121512"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00509 amidination of lysines or N-terminal amines with methyl acetimidate ! amidination of lysines or N-terminal amines with methyl acetimidate
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1354. MOD:01354 Hex1HexNAc1NeuAc1 N4-glycosylated asparagine

Table 1356. Term [MOD:01354]
id	MOD:01354
name	Hex1HexNAc1NeuAc1 N4-glycosylated asparagine
def	"A protein modification that effectively replaces an N4 hydrogen atom of an asparagine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc1 linked through a glycosidic bond." [PubMed:11698400, UniMod:149#N]
synonym	"Hex(1)HexNAc(1)NeuAc(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc1" RELATED UniMod-description []
xref	DiffAvg: "657.60"
xref	DiffFormula: "C 25 H 41 N 2 O 18"
xref	DiffMono: "657.235437"
xref	Formula: "C 29 H 47 N 4 O 20"
xref	MassAvg: "771.70"
xref	MassMono: "771.278365"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00517 Hex1HexNAc1NeuAc1 glycosylated residue ! Hex1HexNAc1NeuAc1 glycosylated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.1355. MOD:01355 Hex1HexNAc1NeuAc1O-glycosylated threonine

Table 1357. Term [MOD:01355]
id	MOD:01355
name	Hex1HexNAc1NeuAc1O-glycosylated threonine
def	"A protein modification that effectively replaces an O3 hydrogen atom of a threonine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc1 linked through a glycosidic bond." [UniMod:149#T]
synonym	"Hex(1)HexNAc(1)NeuAc(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc1" RELATED UniMod-description []
xref	DiffAvg: "657.60"
xref	DiffFormula: "C 25 H 41 N 2 O 18"
xref	DiffMono: "657.235437"
xref	Formula: "C 29 H 48 N 3 O 20"
xref	MassAvg: "758.70"
xref	MassMono: "758.283116"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00517 Hex1HexNAc1NeuAc1 glycosylated residue ! Hex1HexNAc1NeuAc1 glycosylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1356. MOD:01356 Hex1HexNAc1NeuAc1 O-glycosylated serine

Table 1358. Term [MOD:01356]
id	MOD:01356
name	Hex1HexNAc1NeuAc1 O-glycosylated serine
def	"A protein modification that effectively replaces an O3 hydrogen atom of a serine residue with a carbohydrate-like group composed of Hex1HexNAc1NeuAc1 linked through a glycosidic bond." [PubMed:7856876, UniMod:149#S]
synonym	"Hex(1)HexNAc(1)NeuAc(1)" RELATED PSI-MS-label []
synonym	"Hex1HexNAc1NeuAc1" RELATED UniMod-description []
xref	DiffAvg: "657.60"
xref	DiffFormula: "C 25 H 41 N 2 O 18"
xref	DiffMono: "657.235437"
xref	Formula: "C 28 H 46 N 3 O 20"
xref	MassAvg: "744.68"
xref	MassMono: "744.267466"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00517 Hex1HexNAc1NeuAc1 glycosylated residue ! Hex1HexNAc1NeuAc1 glycosylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1357. MOD:01357 2x(13)C,4x(2)H labeled dimethylated L-lysine

Table 1359. Term [MOD:01357]
id	MOD:01357
name	2x(13)C,4x(2)H labeled dimethylated L-lysine
def	"A protein modification that effectively replaces two hydrogen atoms of an L-lysine residue containing common isotopes with two (13)C,3x(2)H labeled methyl groups to form a 2x(13)C,6x(2)H labeled dimethylated L-lysine." [PubMed:12686488, PubMed:16335955, UniMod:510#K]
synonym	"DiMethyl-C13HD2" RELATED UniMod-description []
synonym	"Dimethyl:2H(4)13C(2)" RELATED PSI-MS-label []
xref	DiffAvg: "34.06"
xref	DiffFormula: "(13)C 2 (2)H 4"
xref	DiffMono: "34.063117"
xref	Formula: "(12)C 6 (13)C 2 (1)H 12 (2)H 4 N 2 O 1"
xref	MassAvg: "162.16"
xref	MassMono: "162.158080"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:00927 2x(13)C,4x(2)H labeled dimethylated residue ! 2x(13)C,4x(2)H labeled dimethylated residue
relationship	derives_from MOD:00084 N6,N6-dimethyl-L-lysine ! N6,N6-dimethyl-L-lysine

2.1358. MOD:01358 Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form - site N-term

Table 1360. Term [MOD:01358]
id	MOD:01358
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form - site N-term
def	"modification from UniMod Isotopic label - Use when labelling post-digest" [PubMed:15602776, UniMod:687#N-term]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form" RELATED UniMod-description []
synonym	"ICPL:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "109.05"
xref	DiffFormula: "C 6 (1)H -1 (2)H 4 N 1 O 1"
xref	DiffMono: "109.046571"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1359. MOD:01359 Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form - site K

Table 1361. Term [MOD:01359]
id	MOD:01359
name	Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form - site K
def	"modification from UniMod Isotopic label - Use when labelling post-digest" [PubMed:15602776, UniMod:687#K]
synonym	"Bruker Daltonics SERVA-ICPL™ quantification chemistry, medium form" RELATED UniMod-description []
synonym	"ICPL:2H(4)" RELATED PSI-MS-label []
xref	DiffAvg: "109.05"
xref	DiffFormula: "C 6 (1)H -1 (2)H 4 N 1 O 1"
xref	DiffMono: "109.046571"
xref	Formula: "C 12 (1)H 11 (2)H 4 N 3 O 2"
xref	MassAvg: "237.14"
xref	MassMono: "237.141534"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1360. MOD:01360 4-sulfophenyl isothiocyanate N6-derivatized lysine

Table 1362. Term [MOD:01360]
id	MOD:01360
name	4-sulfophenyl isothiocyanate N6-derivatized lysine
def	"A protein modification that effectively converts an L-lysine residue to the 4-sulfophenyl isothiocyanate adduct, N6-[(4-sulfophenyl)carbamothioyl]lysine." [PubMed:14689565, PubMed:14745769, PubMed:15549660, PubMed:16526082, UniMod:261#K]
synonym	"4-sulfophenyl isothiocyanate" RELATED UniMod-description []
synonym	"N6-[(4-sulfophenyl)carbamothioyl]lysine" EXACT PSI-MOD-alternate []
synonym	"SPITC" RELATED PSI-MS-label []
xref	DiffAvg: "215.24"
xref	DiffFormula: "C 7 H 5 N 1 O 3 S 2"
xref	DiffMono: "214.971085"
xref	Formula: "C 13 H 17 N 3 O 4 S 2"
xref	MassAvg: "343.42"
xref	MassMono: "343.066048"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00584 4-sulfophenyl isothiocyanate derivatized residue ! 4-sulfophenyl isothiocyanate derivatized residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1361. MOD:01361 O-thiophospho-L-threonine

Table 1363. Term [MOD:01361]
id	MOD:01361
name	O-thiophospho-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-thiophospho-L-threonine." [PubMed:11507762, PubMed:12110917, UniMod:260#T]
synonym	"Thiophospho" RELATED PSI-MS-label []
synonym	"Thiophosphorylation" RELATED UniMod-description []
xref	DiffAvg: "96.04"
xref	DiffFormula: "H 1 O 2 P 1 S 1"
xref	DiffMono: "95.943487"
xref	Formula: "C 4 H 8 N 1 O 4 P 1 S 1"
xref	MassAvg: "197.14"
xref	MassMono: "196.991165"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00583 thiophosphorylated residue ! thiophosphorylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1362. MOD:01362 O-thiophospho-L-serine

Table 1364. Term [MOD:01362]
id	MOD:01362
name	O-thiophospho-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-thiophospho-L-serine." [PubMed:11507762, PubMed:12110917, UniMod:260#S]
synonym	"Thiophospho" RELATED PSI-MS-label []
synonym	"Thiophosphorylation" RELATED UniMod-description []
xref	DiffAvg: "96.04"
xref	DiffFormula: "H 1 O 2 P 1 S 1"
xref	DiffMono: "95.943487"
xref	Formula: "C 3 H 6 N 1 O 4 P 1 S 1"
xref	MassAvg: "183.12"
xref	MassMono: "182.975515"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00583 thiophosphorylated residue ! thiophosphorylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1363. MOD:01363 O4'-thiophospho-L-tyrosine

Table 1365. Term [MOD:01363]
id	MOD:01363
name	O4'-thiophospho-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-thiophospho-L-tyrosine." [PubMed:12110917, PubMed:15549660, UniMod:260#Y]
synonym	"Thiophospho" RELATED PSI-MS-label []
synonym	"Thiophosphorylation" RELATED UniMod-description []
xref	DiffAvg: "96.04"
xref	DiffFormula: "H 1 O 2 P 1 S 1"
xref	DiffMono: "95.943487"
xref	Formula: "C 9 H 10 N 1 O 4 P 1 S 1"
xref	MassAvg: "259.22"
xref	MassMono: "259.006815"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00583 thiophosphorylated residue ! thiophosphorylated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1364. MOD:01364 fluorescein-5-thiosemicarbazide - site S

Table 1366. Term [MOD:01364]
id	MOD:01364
name	fluorescein-5-thiosemicarbazide - site S
def	"modification from UniMod Chemical derivative -" [PubMed:11467524, UniMod:478#S]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "C 24 H 20 N 4 O 7 S 1"
xref	MassAvg: "508.51"
xref	MassMono: "508.105270"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00626 fluorescein-5-thiosemicarbazide ! fluorescein-5-thiosemicarbazide
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1365. MOD:01365 fluorescein-5-thiosemicarbazide - site C

Table 1367. Term [MOD:01365]
id	MOD:01365
name	fluorescein-5-thiosemicarbazide - site C
def	"modification from UniMod Chemical derivative -" [UniMod:478#C]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "C 24 H 20 N 4 O 6 S 2"
xref	MassAvg: "524.57"
xref	MassMono: "524.082426"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00626 fluorescein-5-thiosemicarbazide ! fluorescein-5-thiosemicarbazide
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1366. MOD:01366 fluorescein-5-thiosemicarbazide - site K

Table 1368. Term [MOD:01366]
id	MOD:01366
name	fluorescein-5-thiosemicarbazide - site K
def	"modification from UniMod Chemical derivative -" [UniMod:478#K]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "C 27 H 27 N 5 O 6 S 1"
xref	MassAvg: "549.60"
xref	MassMono: "549.168205"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00626 fluorescein-5-thiosemicarbazide ! fluorescein-5-thiosemicarbazide
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1367. MOD:01367 fluorescein-5-thiosemicarbazide - site P

Table 1369. Term [MOD:01367]
id	MOD:01367
name	fluorescein-5-thiosemicarbazide - site P
def	"modification from UniMod Chemical derivative -" [UniMod:478#P]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "C 26 H 22 N 4 O 6 S 1"
xref	MassAvg: "518.54"
xref	MassMono: "518.126005"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00626 fluorescein-5-thiosemicarbazide ! fluorescein-5-thiosemicarbazide
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.1368. MOD:01368 fluorescein-5-thiosemicarbazide - site R

Table 1370. Term [MOD:01368]
id	MOD:01368
name	fluorescein-5-thiosemicarbazide - site R
def	"modification from UniMod Chemical derivative -" [PubMed:15525938, UniMod:478#R]
synonym	"fluorescein-5-thiosemicarbazide" RELATED UniMod-description []
synonym	"FTC" RELATED PSI-MS-label []
xref	DiffAvg: "421.43"
xref	DiffFormula: "C 21 H 15 N 3 O 5 S 1"
xref	DiffMono: "421.073242"
xref	Formula: "C 27 H 27 N 7 O 6 S 1"
xref	MassAvg: "577.62"
xref	MassMono: "577.174353"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00626 fluorescein-5-thiosemicarbazide ! fluorescein-5-thiosemicarbazide
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.1369. MOD:01369 deamidated and methyl esterified residue

Table 1371. Term [MOD:01369]
id	MOD:01369
name	deamidated and methyl esterified residue
def	"A protein modification that effectively replaces a carboxamido group with a carboxyl methyl ester group." [UniMod:528]
subset	PSI-MOD-slim
synonym	"Deamidation followed by a methylation" RELATED UniMod-description []
synonym	"Methyl+Deamidated" RELATED PSI-MS-label []
xref	DiffAvg: "15.01"
xref	DiffFormula: "C 1 H 1 N -1 O 1"
xref	DiffMono: "14.999666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00393 O-methylated residue ! O-methylated residue
is_a	MOD:00400 deamidated residue ! deamidated residue

2.1370. MOD:01370 6x(13)C,1x(15)N labeled residue

Table 1372. Term [MOD:01370]
id	MOD:01370
name	6x(13)C,1x(15)N labeled residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 6x(13)C,1x(15)N labeled residue." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:695]
synonym	"13C(6) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(6)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "7.02"
xref	DiffFormula: "(12)C -6 (13)C 6 (14)N -1 (15)N 1"
xref	DiffMono: "7.017164"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue

2.1371. MOD:01371 deamidation in presence of O18

Table 1373. Term [MOD:01371]
id	MOD:01371
name	deamidation in presence of O18
def	"OBSOLETE bcecause identical and redundant with MOD:00851. Remap to MOD:00851." [PubMed:8382902]
synonym	"Deamidated:18O(1)" RELATED PSI-MS-label []
synonym	"Deamidation in presence of O18" RELATED UniMod-description []
xref	DiffAvg: "2.99"
xref	DiffFormula: "H -1 N -1 (18)O 1"
xref	DiffMono: "2.988262"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1372. MOD:01372 (2S)-4-hydroxyleucine

Table 1374. Term [MOD:01372]
id	MOD:01372
name	(2S)-4-hydroxyleucine
def	"A protein modification that effectively converts an L-leucine residue to a (2S)-4-hydroxyleucine." [PubMed:363352, PubMed:9164839, RESID:AA0442]
synonym	"(2S)-2-amino-4-hydroxy-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S)-4-hydroxyleucine" EXACT RESID-name []
synonym	"gamma-hydroxyleucine" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 11 N 1 O 2"
xref	MassAvg: "129.16"
xref	MassMono: "129.078979"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01411 monohydroxylated leucine ! monohydroxylated leucine

2.1373. MOD:01373 (2S,4R)-5-hydroxyleucine

Table 1375. Term [MOD:01373]
id	MOD:01373
name	(2S,4R)-5-hydroxyleucine
def	"A protein modification that effectively converts an L-leucine residue to a (2S,4R)-5-hydroxyleucine." [PubMed:16858410, PubMed:7690768, PubMed:9164839, RESID:AA0443]
synonym	"(2S,4R)-2-amino-5-hydroxy-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,4R)-5-hydroxyleucine" EXACT RESID-name []
synonym	"(4R)-5-hydroxyleucine" EXACT RESID-alternate []
synonym	"delta-hydroxyleucine" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 11 N 1 O 2"
xref	MassAvg: "129.16"
xref	MassMono: "129.078979"
xref	Origin: "L"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01411 monohydroxylated leucine ! monohydroxylated leucine

2.1374. MOD:01374 (2S,4R)-5-oxoleucine

Table 1376. Term [MOD:01374]
id	MOD:01374
name	(2S,4R)-5-oxoleucine
def	"A modification that effectively oxygenates C5 of an L-leucine residue to form a (2S,4R)-5-oxoleucine." [ChEBI:43739, PubMed:16858410, RESID:AA0444]
synonym	"(2S,4R)-2-amino-4-methyl-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(2S,4R)-5-oxoleucine" EXACT RESID-name []
synonym	"(4R)-5-oxo-L-leucine" EXACT RESID-alternate []
xref	DiffAvg: "13.98"
xref	DiffFormula: "C 0 H -2 N 0 O 1"
xref	DiffMono: "13.979265"
xref	Formula: "C 6 H 9 N 1 O 2"
xref	MassAvg: "127.14"
xref	MassMono: "127.063329"
xref	Origin: "L"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.1375. MOD:01375 (2S,4R)-4,5-dihydroxyleucine

Table 1377. Term [MOD:01375]
id	MOD:01375
name	(2S,4R)-4,5-dihydroxyleucine
def	"A protein modification that effectively converts an L-leucine residue to a (2S,4R)-4,5-dihydroxyleucine." [PubMed:6010785, PubMed:6893271, RESID:AA0445]
synonym	"(2S,4R)-2-amino-4,5-dihydroxy-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,4R)-4,5-dihydroxyleucine" EXACT RESID-name []
synonym	"(4R)-4,5-dihydroxyleucine" EXACT RESID-alternate []
synonym	"gamma,delta-dihydroxyleucine" EXACT RESID-alternate []
synonym	"MOD_RES (4R)-4,5-dihydroxyleucine" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01412 dihydroxylated leucine ! dihydroxylated leucine

2.1376. MOD:01376 (2S,3S,4R)-3,4-dihydroxyisoleucine

Table 1378. Term [MOD:01376]
id	MOD:01376
name	(2S,3S,4R)-3,4-dihydroxyisoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a (2S,3S,4R)-3,4-dihydroxyisoleucine." [PubMed:11320328, RESID:AA0447]
synonym	"(2S,3S,4R)-2-amino-3,4-dihydroxy-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3S,4R)-3,4-dihydroxyisoleucine" EXACT RESID-name []
synonym	"(3S,4R)-3,4-dihydroxyisoleucine" EXACT RESID-alternate []
synonym	"beta,gamma-dihydroxyisoleucine" EXACT RESID-alternate []
synonym	"MOD_RES (3S,4R)-3,4-dihydroxyisoleucine" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01416 dihydroxylated isoleucine ! dihydroxylated isoleucine

2.1377. MOD:01377 (2S,3R,4S)-4-hydroxyisoleucine

Table 1379. Term [MOD:01377]
id	MOD:01377
name	(2S,3R,4S)-4-hydroxyisoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a (2S,3R,4S)-4-hydroxyisoleucine." [PubMed:363352, RESID:AA0448]
synonym	"(2S,3R,4S)-2-amino-3-methyl-4-hydroxyvaleric acid" EXACT RESID-alternate []
synonym	"(2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R,4S)-4-hydroxyisoleucine" EXACT RESID-name []
synonym	"(3R,4S)-4-hydroxyisoleucine" EXACT RESID-alternate []
synonym	"gamma-hydroxyisoleucine" EXACT RESID-alternate []
synonym	"MOD_RES (3R,4S)-4-hydroxyisoleucine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 11 N 1 O 2"
xref	MassAvg: "129.16"
xref	MassMono: "129.078979"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01415 monohydroxylated isoleucine ! monohydroxylated isoleucine

2.1378. MOD:01378 (2S,3R,4R)-4,5-dihydroxyisoleucine

Table 1380. Term [MOD:01378]
id	MOD:01378
name	(2S,3R,4R)-4,5-dihydroxyisoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a (2S,3R,4R)-4,5-dihydroxyisoleucine." [PubMed:11805306, PubMed:18552824, PubMed:363352, RESID:AA0449]
synonym	"(2S,3R,4R)-2-amino-4,5-dihydroxy-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R,4R)-4,5-dihydroxyisoleucine" EXACT RESID-name []
synonym	"(3R,4R)-4,5-dihydroxyisoleucine" EXACT RESID-alternate []
synonym	"gamma,delta-dihydroxyisoleucine" EXACT RESID-alternate []
synonym	"MOD_RES (3R,4R)-4,5-dihydroxyisoleucine" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01416 dihydroxylated isoleucine ! dihydroxylated isoleucine

2.1379. MOD:01379 2'-methylsulfonyl-L-tryptophan

Table 1381. Term [MOD:01379]
id	MOD:01379
name	2'-methylsulfonyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 2'-methylsulfonyl-L-tryptophan." [PubMed:6893271, RESID:AA0450]
synonym	"2'-methylsulfonyl-L-tryptophan" EXACT RESID-name []
synonym	"2-methylsulfonyl-3-((2S)-2-amino-2-carboxyethyl)-1H-indole" EXACT RESID-systematic []
synonym	"MOD_RES 2'-methylsulfonyltryptophan" EXACT UniProt-feature []
xref	DiffAvg: "78.09"
xref	DiffFormula: "C 1 H 2 N 0 O 2 S 1"
xref	DiffMono: "77.977550"
xref	Formula: "C 12 H 12 N 2 O 3 S 1"
xref	MassAvg: "264.30"
xref	MassMono: "264.056863"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1380. MOD:01380 2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide

Table 1382. Term [MOD:01380]
id	MOD:01380
name	2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-tryptophan residue by a thioether bond to form 2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide." [PubMed:11805306, PubMed:18552824, PubMed:363352, PubMed:4865716, RESID:AA0451]
comment	Cross-link 2.
synonym	"2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide" EXACT RESID-name []
synonym	"2-((2R)-2-amino-2carboxyethyl)sulfinyl-3-((2S)-2-amino-2-carboxyethyl)-1H-indole" EXACT RESID-systematic []
synonym	"6'-hydroxy-S-oxo-tryptathionine" EXACT RESID-alternate []
synonym	"CROSSLNK 2'-cysteinyl-6'-hydroxytryptophan sulfoxide (Trp-Cys)" EXACT UniProt-feature []
xref	DiffAvg: "29.98"
xref	DiffFormula: "C 0 H -2 N 0 O 2 S 0"
xref	DiffMono: "29.974179"
xref	Formula: "C 14 H 13 N 3 O 4 S 1"
xref	MassAvg: "319.33"
xref	MassMono: "319.062677"
xref	Origin: "C, W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1381. MOD:01381 O-palmitoleyl-L-serine

Table 1383. Term [MOD:01381]
id	MOD:01381
name	O-palmitoleyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-palmitoleyl-L-serine." [OMSSA:186, PubMed:17141155, RESID:AA0455]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-((9Z)-9-hexadecenoyloxy)propanoic acid" EXACT RESID-systematic []
synonym	"L-serine cis-9-hexadecenoate ester" EXACT RESID-alternate []
synonym	"LIPID O-palmitoleyl serine" EXACT UniProt-feature []
synonym	"mod186" EXACT OMSSA-label []
synonym	"O-palmitoleyl-L-serine" EXACT RESID-name []
synonym	"O3-palmitoleyl-serine" EXACT RESID-alternate []
xref	DiffAvg: "236.40"
xref	DiffFormula: "C 16 H 28 N 0 O 1"
xref	DiffMono: "236.214016"
xref	Formula: "C 19 H 33 N 1 O 3"
xref	MassAvg: "323.48"
xref	MassMono: "323.246044"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01768 O-palmitoleylated residue ! O-palmitoleylated residue

2.1382. MOD:01382 N,N,N-trimethyl-L-methionine

Table 1384. Term [MOD:01382]
id	MOD:01382
name	N,N,N-trimethyl-L-methionine
def	"A protein modification that effectively converts an L-methionine residue to N,N,N-trimethyl-L-methionine." [PubMed:18611379, RESID:AA0456]
subset	PSI-MOD-slim
synonym	"(1S)-1-carboxy-N,N,N-trimethyl-3-(methylsulfanyl)propanaminium" EXACT RESID-systematic []
synonym	"(1S)-1-carboxy-N,N,N-trimethyl-3-(methylsulfanyl)propanazanium" EXACT RESID-alternate []
synonym	"2-trimethylammonio-4-(methylthio)butanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N,N,N-trimethylmethionine" EXACT UniProt-feature []
synonym	"N,N,N-trimethyl-L-methionine" EXACT RESID-name []
synonym	"N,N,N-trimethylmethionine cation" EXACT RESID-alternate []
synonym	"N,N,N-trimethylmethioninium" EXACT RESID-alternate []
synonym	"N2Me3+Met" EXACT PSI-MOD-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0 S 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 17 N 1 O 1 S 1"
xref	MassAvg: "175.29"
xref	MassMono: "175.102537"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01463 N-methylated methionine ! N-methylated methionine
is_a	MOD:01698 alpha-amino trimethylated protonated-residue ! alpha-amino trimethylated protonated-residue

2.1383. MOD:01383 L-cystine S-oxide

Table 1385. Term [MOD:01383]
id	MOD:01383
name	L-cystine S-oxide
def	"A protein modification that effectively cross-links two L-cysteine residues and oxidizes a sulfur to form L-cystine S-oxide." [RESID:AA0457]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-[([(2R)-2-amino-2-carboxyethyl]sulfanyl)sulfinyl]propanoic acid" EXACT RESID-systematic []
synonym	"CROSSLNK S-cysteinyl 3-(oxidosulfanyl)alanine (Cys-Cys)" EXACT UniProt-feature []
synonym	"cystine sulfoxide" EXACT RESID-alternate []
synonym	"L-cystine S-oxide" EXACT RESID-name []
synonym	"S-[(2R)-2-amino-3-oxopropyl] (2R)-2-amino-3-oxopropane-1-sulfinothioate" EXACT RESID-alternate []
synonym	"S-cysteinyl 3-(oxidosulfanyl)alanine" EXACT RESID-alternate []
xref	DiffAvg: "13.98"
xref	DiffFormula: "C 0 H -2 N 0 O 1 S 0"
xref	DiffMono: "13.979265"
xref	Formula: "C 6 H 8 N 2 O 3 S 2"
xref	MassAvg: "220.26"
xref	MassMono: "219.997634"
xref	Origin: "C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00689 disulfide crosslinked residues ! disulfide crosslinked residues

2.1384. MOD:01384 aminomalonic acid (Ser)

Table 1386. Term [MOD:01384]
id	MOD:01384
name	aminomalonic acid (Ser)
def	"A protein modification that effectively converts an L-serine residue to an aminomalonic acid." [PubMed:1621954, PubMed:5415959, PubMed:6366787, PubMed:7457858, RESID:AA0458]
synonym	"2-carboxyglycine" EXACT RESID-alternate []
synonym	"Ama" EXACT RESID-alternate []
synonym	"aminomalonic acid" EXACT RESID-name []
synonym	"aminopropanedioic acid" EXACT RESID-systematic []
synonym	"MOD_RES Aminomalonic acid (Ser)" EXACT UniProt-feature []
xref	DiffAvg: "13.98"
xref	DiffFormula: "C 0 H -2 N 0 O 1 S 0"
xref	DiffMono: "13.979265"
xref	Formula: "C 3 H 3 N 1 O 3"
xref	MassAvg: "101.06"
xref	MassMono: "101.011293"
xref	Origin: "S"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1385. MOD:01385 3-hydroxy-L-phenylalanine

Table 1387. Term [MOD:01385]
id	MOD:01385
name	3-hydroxy-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to 3-hydroxy-L-phenylalanine." [ChEBI:16795, OMSSA:63, PubMed:10625477, PubMed:15651011, PubMed:16734421, PubMed:1880060, PubMed:7398618, PubMed:7844053, RESID:AA0462]
synonym	"(2S,3S)-2-amino-3-hydroxy-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"3-hydoxyphenylalanine" EXACT RESID-alternate []
synonym	"3-hydroxy-L-phenylalanine" EXACT RESID-name []
synonym	"3-phenyl-L-serine" EXACT RESID-alternate []
synonym	"3HyPhe" EXACT PSI-MOD-label []
synonym	"beta-hydroxyphenylalanine" EXACT RESID-alternate []
synonym	"beta-phenylserine" EXACT RESID-alternate []
synonym	"hydroxylationf" EXACT OMSSA-label []
synonym	"L-threo-3-phenylserine" EXACT RESID-alternate []
synonym	"MOD_RES 3-hydroxyphenylalanine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 9 H 9 N 1 O 2"
xref	MassAvg: "163.18"
xref	MassMono: "163.063329"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue

2.1386. MOD:01386 3-hydroxy-L-valine

Table 1388. Term [MOD:01386]
id	MOD:01386
name	3-hydroxy-L-valine
def	"A protein modification that effectively converts an L-valine residue to 3-hydroxy-L-valine." [PubMed:7328054, RESID:AA0463]
synonym	"(2S)-2-amino-3-hydroxy-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"3-hydroxy-L-valine" EXACT RESID-name []
synonym	"3-hydroxyvaline" EXACT RESID-alternate []
synonym	"3HyVal" EXACT PSI-MOD-label []
synonym	"MOD_RES 3-hydroxyvaline" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2"
xref	MassAvg: "115.13"
xref	MassMono: "115.063329"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue

2.1387. MOD:01387 O-methyl-L-threonine

Table 1389. Term [MOD:01387]
id	MOD:01387
name	O-methyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-methyl-L-threonine." [PubMed:7328054, RESID:AA0464]
synonym	"(2S,3R)-2-amino-3-methoxybutanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES O-methylthreonine" EXACT UniProt-feature []
synonym	"O-methyl threonine" EXACT RESID-alternate []
synonym	"O-methyl-L-threonine" EXACT RESID-name []
synonym	"OMeThr" EXACT PSI-MOD-label []
synonym	"threonine methyl ether" EXACT RESID-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 5 H 9 N 1 O 2"
xref	MassAvg: "115.13"
xref	MassMono: "115.063329"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01803 O-methylated threonine ! O-methylated threonine

2.1388. MOD:01388 1-amino-2-propanol

Table 1390. Term [MOD:01388]
id	MOD:01388
name	1-amino-2-propanol
def	"A protein modification that effectively converts an L-threonine residue into 1-amino-2-propanol." [ChEBI:15675, PubMed:7328054, RESID:AA0465]
synonym	"(2R)-1-aminopropan-2-ol" EXACT RESID-systematic []
synonym	"1-amino-2-hydroxypropane" EXACT RESID-alternate []
synonym	"1-amino-2-propanol" EXACT RESID-name []
synonym	"1-methyl-2-aminoethanol" EXACT RESID-alternate []
synonym	"2-amino-1-methylethanol" EXACT RESID-alternate []
synonym	"2-hydroxy-1-propylamine" EXACT RESID-alternate []
synonym	"2-hydroxypropanamine" EXACT RESID-alternate []
synonym	"2-hydroxypropylamine" EXACT RESID-alternate []
synonym	"alpha-aminoisopropyl alcohol" EXACT RESID-alternate []
synonym	"dCbxThr" EXACT PSI-MOD-label []
synonym	"decarboxylated threonine" EXACT RESID-alternate []
synonym	"isopropanolamine" EXACT RESID-alternate []
synonym	"MOD_RES Decarboxylated threonine" EXACT UniProt-feature []
synonym	"threamine" EXACT RESID-alternate []
xref	DiffAvg: "-44.01"
xref	DiffFormula: "C -1 H 0 N 0 O -2"
xref	DiffMono: "-43.989829"
xref	Formula: "C 3 H 8 N 1 O 1"
xref	MassAvg: "74.10"
xref	MassMono: "74.060589"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00960 decarboxylated residue ! decarboxylated residue

2.1389. MOD:01389 L-isoleucine thiazole-4-carboxylic acid

Table 1391. Term [MOD:01389]
id	MOD:01389
name	L-isoleucine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-isoleucine residue to form L-isoleucine thiazole-4-carboxylic acid." [PubMed:11320328, RESID:AA0466]
comment	Cross-link 2.
synonym	"2-[(1S,2S)-1-amino-2-methylbutyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-zanyl-2-methylbutyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Ile-Cys)" EXACT UniProt-feature []
synonym	"L-isoleucine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 9 H 12 N 2 O 1 S 1"
xref	MassAvg: "196.27"
xref	MassMono: "196.067034"
xref	Origin: "C, I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1390. MOD:01390 L-valine thiazole-4-carboxylic acid

Table 1392. Term [MOD:01390]
id	MOD:01390
name	L-valine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-valine residue to form L-valine thiazole-4-carboxylic acid." [PubMed:7328054, RESID:AA0467]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-methylpropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-methylpropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Val-Cys)" EXACT UniProt-feature []
synonym	"L-valine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 8 H 10 N 2 O 1 S 1"
xref	MassAvg: "182.24"
xref	MassMono: "182.051384"
xref	Origin: "C, V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1391. MOD:01391 L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid

Table 1393. Term [MOD:01391]
id	MOD:01391
name	L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-valine residue, and C-5 methoxymethylates to form L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid." [PubMed:10625477, PubMed:1880060, PubMed:7844053, RESID:AA0468]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-methylpropyl]-5-(methoxymethyl)-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-methylpropyl]-5-(methoxymethyl)-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 5-(methoxymethyl)thiazole-4-carboxylic acid (Val-Cys)" EXACT UniProt-feature []
synonym	"L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "24.02"
xref	DiffFormula: "C 2 H 0 N 0 O 0 S 0"
xref	DiffMono: "24.000000"
xref	Formula: "C 10 H 14 N 2 O 2 S 1"
xref	MassAvg: "226.29"
xref	MassMono: "226.077599"
xref	Origin: "C, V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1392. MOD:01392 L-asparagine 5-methylthiazole-4-carboxylic acid

Table 1394. Term [MOD:01392]
id	MOD:01392
name	L-asparagine 5-methylthiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-asparagine residue, and C-4 methylates to form L-asparagine 5-methylthiazole-4-carboxylic acid." [PubMed:10625477, PubMed:1880060, PubMed:7844053, RESID:AA0469]
comment	Cross-link 2.
synonym	"2-[(1S)-1,3-bisazanyl-3-oxopropyl]-5-methyl-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"2-[(1S)-1,3-diamino-3-oxopropyl]-5-methyl-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"CROSSLNK 5-methylthiazole-4-carboxylic acid (Asn-Cys)" EXACT UniProt-feature []
synonym	"L-asparagine 5-methylthiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-6.00"
xref	DiffFormula: "C 1 H -2 N 0 O -1 S 0"
xref	DiffMono: "-6.010565"
xref	Formula: "C 8 H 9 N 3 O 2 S 1"
xref	MassAvg: "211.24"
xref	MassMono: "211.041548"
xref	Origin: "C, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue
relationship	derives_from MOD:00656 C-methylated residue ! C-methylated residue

2.1393. MOD:01393 L-cysteine pyridine-2,5-dicarboxylic acid

Table 1395. Term [MOD:01393]
id	MOD:01393
name	L-cysteine pyridine-2,5-dicarboxylic acid
def	"A protein modification that crosslinks two serine residues and a cysteine residue by formation of a pyridine-2,5-dicarboxylic acid." [PubMed:10625477, PubMed:1880060, PubMed:7844053, RESID:AA0470]
comment	Cross-link 3.
synonym	"6-[(1R)-1-amino-2-sulfanylethyl]pyridine-2,5-dicarboxylic acid" EXACT RESID-systematic []
synonym	"L-cysteine pyridine-2,5-dicarboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-70.07"
xref	DiffFormula: "C 0 H -8 N -1 O -3 S 0"
xref	DiffMono: "-70.050418"
xref	Formula: "C 9 H 7 N 2 O 2 S 1"
xref	MassAvg: "207.23"
xref	MassMono: "207.022823"
xref	Origin: "C, S, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01425 pyridinyl ring crosslinked residues ! pyridinyl ring crosslinked residues

2.1394. MOD:01394 L-cysteine 5-amino-3,4,5,6-tetrahydropyridine-2,5-dicarboxylic acid

Table 1396. Term [MOD:01394]
id	MOD:01394
name	L-cysteine 5-amino-3,4,5,6-tetrahydropyridine-2,5-dicarboxylic acid
def	"A protein modification that crosslinks two serine residues and a cysteine residue by formation of a 5-amino-3,4,5,6-tetrahydropyridine-2,5-dicarboxylic acid." [PubMed:11320328, RESID:AA0471]
comment	Cross-link 3.
synonym	"(5R,6R)-5-amino-6-[(1R)-1-amino-2-sulfanylethyl]-3,4,5,6-tetrahydropyridine-2,5-dicarboxylic acid" EXACT RESID-systematic []
synonym	"L-cysteine 5-amino-3,4,5,6-tetrahydropyridine-2,5-dicarboxylic acid" EXACT RESID-name []
synonym	"L-cysteine 5-aminopiperideine-2,5-dicarboxylic acid" EXACT RESID-alternate []
xref	DiffAvg: "-53.04"
xref	DiffFormula: "C 0 H -5 N 0 O -3 S 0"
xref	DiffMono: "-53.023869"
xref	Formula: "C 9 H 11 N 3 O 2 S 1"
xref	MassAvg: "225.27"
xref	MassMono: "225.057198"
xref	Origin: "C, S, S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01425 pyridinyl ring crosslinked residues ! pyridinyl ring crosslinked residues

2.1395. MOD:01395 4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-ol

Table 1397. Term [MOD:01395]
id	MOD:01395
name	4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-ol
def	"A protein modification that effectively results from forming an adduct between an isoleucine residue, a threonine residue and the quinaldate compound 2-carboxy-4-(1-hydroxyethyl)--7,8-dihydroquinolin-8-ol." [PubMed:11320328, RESID:AA0472]
comment	Cross-link 2.
synonym	"(7R,8S)-7-[(1S,2S)-1-carboxy-2-methylbutyl]amino-2-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)carbonyl-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinoline" EXACT RESID-systematic []
synonym	"4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-ol" EXACT RESID-name []
synonym	"BINDING 4-(1-hydroxyethyl)-7,8-dihydroquinolin-8-ol (covalent; via 2 links)" EXACT UniProt-feature []
xref	DiffAvg: "215.21"
xref	DiffFormula: "C 12 H 9 N 1 O 3"
xref	DiffMono: "215.058243"
xref	Formula: "C 22 H 28 N 3 O 6"
xref	MassAvg: "430.48"
xref	MassMono: "430.197811"
xref	Origin: "I, T"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01424 quinaldate modified residue ! quinaldate modified residue

2.1396. MOD:01396 5-hydroxy-3-methyl-L-proline (Pro)

Table 1398. Term [MOD:01396]
id	MOD:01396
name	5-hydroxy-3-methyl-L-proline (Pro)
def	"A protein modification that effectively converts an L-proline residue to a 5-hydroxy-3-methyl-L-proline." [PubMed:7592021, PubMed:8557573, RESID:AA0473]
comment	This entry is for the hypothetical formation of 5-hydroxy-3-methyl-L-proline from proline. For the natural production from L-isoleucine, use MOD:01897 [JSG].
synonym	"(2S,3S,5Xi)-5-hydroxy-3-methylpyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"5-hydroxy-3-methyl-L-proline" EXACT RESID-name []
synonym	"5-hydroxy-3-methylproline" EXACT RESID-alternate []
synonym	"5Hy3MePro" EXACT PSI-MOD-label []
synonym	"beta-methyl-delta-hydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES 5-hydroxy-3-methylproline (Ile)" EXACT UniProt-feature []
xref	DiffAvg: "30.03"
xref	DiffFormula: "C 1 H 2 N 0 O 1"
xref	DiffMono: "30.010565"
xref	Formula: "C 6 H 9 N 1 O 2"
xref	MassAvg: "127.14"
xref	MassMono: "127.063329"
xref	Origin: "P"
xref	Source: "artifactual"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
relationship	has_functional_parent MOD:01024 monohydroxylated proline ! monohydroxylated proline
relationship	has_functional_parent MOD:01417 monomethylated proline ! monomethylated proline

2.1397. MOD:01397 L-serine 5-methyloxazole-4-carboxylic acid

Table 1399. Term [MOD:01397]
id	MOD:01397
name	L-serine 5-methyloxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-serine residue and an L-threonine residue to form L-serine 5-methyloxazole-4-carboxylic acid." [PubMed:7592021, PubMed:8557573, RESID:AA0474]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-hydroxyethyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-hydroxyethyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 5-methyloxazole-4-carboxylic acid (Ser-Thr)" EXACT UniProt-feature []
synonym	"L-serine 5-methyloxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 8 N 2 O 3"
xref	MassAvg: "168.15"
xref	MassMono: "168.053492"
xref	Origin: "S, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01422 oxazole/oxazoline ring crosslinked residues (Thr) ! oxazole/oxazoline ring crosslinked residues (Thr)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1398. MOD:01398 N6-propanoyl-L-lysine

Table 1400. Term [MOD:01398]
id	MOD:01398
name	N6-propanoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-propanoyl-L-lysine." [PubMed:17267393, PubMed:17684016, PubMed:20715035, RESID:AA0475, UniMod:58#K]
comment	The binding of histone peptides with propanoylated lysine to nuclear bromodomain proteins is non-specific and weaker than binding to the corresponding acetylated lysine peptides [JSG].
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(propanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-6-propionylaminocaproic acid" EXACT RESID-alternate []
synonym	"epsilon-propanoyl-L-lysine" EXACT RESID-alternate []
synonym	"epsilon-propionyl-L-lysine" EXACT RESID-alternate []
synonym	"N(zeta)-propanoyllysine" EXACT RESID-alternate []
synonym	"N6-(1-oxopropyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-propanoyl-L-lysine" EXACT RESID-name []
synonym	"N6-propionyllysine" EXACT RESID-alternate []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 N 0 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "C 9 H 16 N 2 O 2"
xref	MassAvg: "184.24"
xref	MassMono: "184.121178"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01155 lipoconjugated residue ! lipoconjugated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
is_a	MOD:01894 propanoylated residue ! propanoylated residue

2.1399. MOD:01399 N6-(ADP-ribosyl)-L-lysine

Table 1401. Term [MOD:01399]
id	MOD:01399
name	N6-(ADP-ribosyl)-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to an N6-(ADP-ribosyl)-L-lysine." [PubMed:18436469, RESID:AA0476]
synonym	"(S)-2-amino-6-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-amino-6-(ADP-ribosyl)amino-hexanoic acid" EXACT RESID-alternate []
synonym	"epsilon-ADP-ribosyllysine" EXACT RESID-alternate []
synonym	"MOD_RES N6-(ADP-ribosyl)lysine" EXACT UniProt-feature []
synonym	"N(zeta)-ADP-ribosyllysine" EXACT RESID-alternate []
synonym	"N6-(ADP-ribosyl)-L-lysine" EXACT RESID-name []
synonym	"N6-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-lysine" EXACT RESID-alternate []
synonym	"N6-alpha-D-ribofuranosyl-L-lysine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 21 H 33 N 7 O 14 P 2"
xref	MassAvg: "669.48"
xref	MassMono: "669.156072"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1400. MOD:01400 L-lysyl-poly(ADP-ribose)

Table 1402. Term [MOD:01400]
id	MOD:01400
name	L-lysyl-poly(ADP-ribose)
def	"A protein modification that effectively converts an L-lysine residue to an L-lysyl-poly(ADP-ribose)." [PubMed:6772638, RESID:AA0477]
synonym	"L-lysyl-poly(ADP-ribose)" EXACT RESID-name []
synonym	"MOD_RES Lysyl poly(ADP-ribose)" EXACT UniProt-feature []
synonym	"poly[2'-adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with 1alpha-D-ribofuranosyl] (2S)-2,6-diaminohexanoate" EXACT RESID-systematic []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 21 H 34 N 7 O 15 P 2"
xref	MassAvg: "686.48"
xref	MassMono: "686.158812"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1401. MOD:01401 (2S,3S)-3-hydroxyasparagine

Table 1403. Term [MOD:01401]
id	MOD:01401
name	(2S,3S)-3-hydroxyasparagine
def	"A protein modification that effectively converts an L-asparagine residue to a (2S,3S)-3-hydroxyasparagine." [ChEBI:50789, PubMed:11823643, PubMed:12042299, PubMed:12215170, PubMed:17573339, RESID:AA0478]
subset	PSI-MOD-slim
synonym	"(2S,3S)-2,4-diamino-3-hydroxy-4-oxobutanoic acid" EXACT RESID-alternate []
synonym	"(2S,3S)-2-amino-3-hydroxy-4-butanediamic acid" EXACT RESID-systematic []
synonym	"(2S,3S)-3-hydroxyasparagine" EXACT RESID-name []
synonym	"(3S)3HyAsn" EXACT PSI-MOD-label []
synonym	"L-threo-beta-hydroxyasparagine" EXACT RESID-alternate []
synonym	"MOD_RES (3S)-3-hydroxyasparagine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 6 N 2 O 3"
xref	MassAvg: "130.10"
xref	MassMono: "130.037842"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01688 3-hydroxy-L-asparagine ! 3-hydroxy-L-asparagine

2.1402. MOD:01402 (2S,3R,4R)-3,4-dihydroxyproline

Table 1404. Term [MOD:01402]
id	MOD:01402
name	(2S,3R,4R)-3,4-dihydroxyproline
def	"A protein modification that effectively converts an L-proline residue to a (2S,3R,4R)-3,4-dihydroxyproline." [PubMed:6893271, RESID:AA0479]
synonym	"(2S,3R,4R)-3,4-dihydroxyproline" EXACT RESID-name []
synonym	"(2S,3R,4R)-3,4-dihydroxypyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"2,3-trans-3,4-trans-3,4-dihydroxy-L-proline" EXACT RESID-alternate []
synonym	"2-alpha-3-beta-4-alpha-3,4-dihydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES (3R,4R)-3,4-dihydroxyproline" EXACT UniProt-feature []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00866 dihydroxylated proline ! dihydroxylated proline

2.1403. MOD:01403 (2S)-4,5,5'-trihydroxyleucine

Table 1405. Term [MOD:01403]
id	MOD:01403
name	(2S)-4,5,5'-trihydroxyleucine
def	"A protein modification that effectively converts an L-leucine residue to a (2S)-4,5,5'-trihydroxyleucine." [PubMed:6893271, RESID:AA0480]
synonym	"(2S)-2-amino-4,5-dihydroxy-4-(hydroxymethyl)pentanoic acid" EXACT RESID-systematic []
synonym	"(2S)-4,5,5'-trihydroxyleucine" EXACT RESID-name []
synonym	"4,5,5'-trihydroxyleucine" EXACT RESID-alternate []
synonym	"gamma,delta,delta'-trihydroxyleucine" EXACT RESID-alternate []
synonym	"MOD_RES 4,5,4'-trihydroxyleucine" EXACT UniProt-feature []
xref	DiffAvg: "48.00"
xref	DiffFormula: "C 0 H 0 N 0 O 3"
xref	DiffMono: "47.984744"
xref	Formula: "C 6 H 11 N 1 O 4"
xref	MassAvg: "161.16"
xref	MassMono: "161.068808"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01413 trihydroxylated leucine ! trihydroxylated leucine

2.1404. MOD:01404 L-asparagine thiazole-4-carboxylic acid

Table 1406. Term [MOD:01404]
id	MOD:01404
name	L-asparagine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-asparagine residue to form L-asparagine thiazole-4-carboxylic acid." [PubMed:7592021, PubMed:8557573, RESID:AA0481]
comment	Cross-link 2.
synonym	"2-[(1S)-1,3-diamino-3-oxopropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1,3-bisazanyl-3-oxopropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Asn-Cys)" EXACT UniProt-feature []
synonym	"L-asparagine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 7 N 3 O 2 S 1"
xref	MassAvg: "197.21"
xref	MassMono: "197.025897"
xref	Origin: "C, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1405. MOD:01405 L-proline thiazole-4-carboxylic acid

Table 1407. Term [MOD:01405]
id	MOD:01405
name	L-proline thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-proline residue to form L-proline thiazole-4-carboxylic acid." [PubMed:7592021, PubMed:8557573, RESID:AA0482]
comment	Cross-link 2.
synonym	"2-[(2S)-pyrrolidin-2-yl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Pro-Cys)" EXACT UniProt-feature []
synonym	"L-proline thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 8 H 8 N 2 O 1 S 1"
xref	MassAvg: "180.22"
xref	MassMono: "180.035734"
xref	Origin: "C, P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1406. MOD:01406 L-threonine thiazole-4-carboxylic acid

Table 1408. Term [MOD:01406]
id	MOD:01406
name	L-threonine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-threonine residue to form L-threonine thiazole-4-carboxylic acid." [PubMed:11320328, RESID:AA0483]
comment	Cross-link 2.
synonym	"2-[(1S,2R)-1-amino-2-hydroxypropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-hydroxypropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Thr-Cys)" EXACT UniProt-feature []
synonym	"L-threonine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 8 N 2 O 2 S 1"
xref	MassAvg: "184.21"
xref	MassMono: "184.030649"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1407. MOD:01407 L-phenylalanine thiazoline-4-carboxylic acid

Table 1409. Term [MOD:01407]
id	MOD:01407
name	L-phenylalanine thiazoline-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-phenylalanine residue to form L-phenylalanine thiazoline-4-carboxylic acid." [PubMed:7592021, PubMed:8557573, RESID:AA0484]
comment	Cross-link 2.
synonym	"(4R)-2-[(1S)-1-amino-2-phenylethyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-phenylethyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazoline-4-carboxylic acid (Phe-Cys)" EXACT UniProt-feature []
synonym	"L-phenylalanine thiazoline-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 12 H 12 N 2 O 1 S 1"
xref	MassAvg: "232.30"
xref	MassMono: "232.067034"
xref	Origin: "C, F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues

2.1408. MOD:01408 L-threonine thiazoline-4-carboxylic acid

Table 1410. Term [MOD:01408]
id	MOD:01408
name	L-threonine thiazoline-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-threonine residue to form L-threonine thiazoline-4-carboxylic acid." [PubMed:11320328, RESID:AA0485]
comment	Cross-link 2.
synonym	"(4S)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[1-azanyl-2-hydroxypropyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK (4S)-thiazoline-4-carboxylic acid (Thr-Cys)" EXACT UniProt-feature []
synonym	"L-threonine (4S)-thiazoline-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 10 N 2 O 2 S 1"
xref	MassAvg: "186.23"
xref	MassMono: "186.046299"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues

2.1409. MOD:01409 trihydroxylated residue

Table 1411. Term [MOD:01409]
id	MOD:01409
name	trihydroxylated residue
def	"A protein modification that effectively replaces three hydrogen atoms with three hydroxyl groups." [PubMed:18688235]
synonym	"Hy3Res" EXACT PSI-MOD-label []
xref	DiffAvg: "48.00"
xref	DiffFormula: "C 0 H 0 N 0 O 3"
xref	DiffMono: "47.984744"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue

2.1410. MOD:01410 hydroxylated leucine

Table 1412. Term [MOD:01410]
id	MOD:01410
name	hydroxylated leucine
def	"A protein modification that effectively converts an L-leucine residue to an hydroxylated leucine." [PubMed:18688235]
synonym	"HyLeu" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "L"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue

2.1411. MOD:01411 monohydroxylated leucine

Table 1413. Term [MOD:01411]
id	MOD:01411
name	monohydroxylated leucine
def	"A protein modification that effectively converts an L-leucine residue to a monohydroxylated leucine." [PubMed:18688235]
synonym	"Hy1Leu" EXACT PSI-MOD-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 11 N 1 O 2"
xref	MassAvg: "129.16"
xref	MassMono: "129.078979"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:01410 hydroxylated leucine ! hydroxylated leucine

2.1412. MOD:01412 dihydroxylated leucine

Table 1414. Term [MOD:01412]
id	MOD:01412
name	dihydroxylated leucine
def	"A protein modification that effectively converts an L-leucine residue to a dihydroxylated leucine." [PubMed:18688235]
synonym	"Hy2Leu" EXACT PSI-MOD-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:01410 hydroxylated leucine ! hydroxylated leucine

2.1413. MOD:01413 trihydroxylated leucine

Table 1415. Term [MOD:01413]
id	MOD:01413
name	trihydroxylated leucine
def	"A protein modification that effectively converts an L-leucine residue to a trihydroxylated leucine." [PubMed:18688235]
synonym	"Hy3Leu" EXACT PSI-MOD-label []
xref	DiffAvg: "48.00"
xref	DiffFormula: "C 0 H 0 N 0 O 3"
xref	DiffMono: "47.984744"
xref	Formula: "C 6 H 11 N 1 O 4"
xref	MassAvg: "161.16"
xref	MassMono: "161.068808"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01409 trihydroxylated residue ! trihydroxylated residue
is_a	MOD:01410 hydroxylated leucine ! hydroxylated leucine

2.1414. MOD:01414 hydroxylated isoleucine

Table 1416. Term [MOD:01414]
id	MOD:01414
name	hydroxylated isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to an hydroxylated isoleucine." [PubMed:18688235]
synonym	"HyIle" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "I"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue

2.1415. MOD:01415 monohydroxylated isoleucine

Table 1417. Term [MOD:01415]
id	MOD:01415
name	monohydroxylated isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a monohydroxylated isoleucine." [PubMed:18688235]
synonym	"Hy1Ile" EXACT PSI-MOD-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 11 N 1 O 2"
xref	MassAvg: "129.16"
xref	MassMono: "129.078979"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:01414 hydroxylated isoleucine ! hydroxylated isoleucine

2.1416. MOD:01416 dihydroxylated isoleucine

Table 1418. Term [MOD:01416]
id	MOD:01416
name	dihydroxylated isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to a dihydroxylated isoleucine." [PubMed:18688235]
synonym	"Hy2Ile" EXACT PSI-MOD-label []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00428 dihydroxylated residue ! dihydroxylated residue
is_a	MOD:01414 hydroxylated isoleucine ! hydroxylated isoleucine

2.1417. MOD:01417 monomethylated proline

Table 1419. Term [MOD:01417]
id	MOD:01417
name	monomethylated proline
def	"A protein modification that effectively converts an L-proline residue to a monomethylated proline." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"Me1Pro" EXACT PSI-MOD-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 6 H 10 N 1 O 1"
xref	MassAvg: "112.15"
xref	MassMono: "112.076239"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00712 methylated proline ! methylated proline

2.1418. MOD:01418 methylated threonine

Table 1420. Term [MOD:01418]
id	MOD:01418
name	methylated threonine
def	"A protein modification that effectively converts an L-threonine residue to a methylated threonine, such as O-methyl-L-threonine." [PubMed:18688235]
synonym	"MeThr" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1419. MOD:01419 oxazole/oxazoline ring crosslinked residues

Table 1421. Term [MOD:01419]
id	MOD:01419
name	oxazole/oxazoline ring crosslinked residues
def	"A protein modification that crosslinks two residues by condensation of a serine or threonine hydroxyl with the carbonyl of the preceding residue to form an oxazole or oxazoline ring, or by rearrangement and condensation of a cysteine with the carbonyl of the preceding residue to form a 1,3-oxazole-4-carbothionic acid." [PubMed:18688235]
is_a	MOD:00690 oxazole/thiazole ring crosslinked residues ! oxazole/thiazole ring crosslinked residues

2.1420. MOD:01420 thiazole/thiazoline ring croslinked residues

Table 1422. Term [MOD:01420]
id	MOD:01420
name	thiazole/thiazoline ring croslinked residues
def	"A protein modification that crosslinks two residues by condensation of a cysteine thiol with the carbonyl of the preceding residue to form a thiazole or thiazoline ring." [PubMed:18688235]
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00690 oxazole/thiazole ring crosslinked residues ! oxazole/thiazole ring crosslinked residues

2.1421. MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser)

Table 1423. Term [MOD:01421]
id	MOD:01421
name	oxazole/oxazoline ring crosslinked residues (Ser)
def	"A protein modification that crosslinks two residues by condensation of a serine hydroxyl with the carbonyl of the preceding residue to form an oxazole or oxazoline ring." [PubMed:18688235]
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01419 oxazole/oxazoline ring crosslinked residues ! oxazole/oxazoline ring crosslinked residues

2.1422. MOD:01422 oxazole/oxazoline ring crosslinked residues (Thr)

Table 1424. Term [MOD:01422]
id	MOD:01422
name	oxazole/oxazoline ring crosslinked residues (Thr)
def	"A protein modification that crosslinks two residues by condensation of a threonine hydroxyl with the carbonyl of the preceding residue to form a 5-methyloxazole or 5-methyloxazoline ring." [PubMed:18688235]
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01419 oxazole/oxazoline ring crosslinked residues ! oxazole/oxazoline ring crosslinked residues

2.1423. MOD:01423 palmitoleylated residue

Table 1425. Term [MOD:01423]
id	MOD:01423
name	palmitoleylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a palmitoleyl group." [UniMod:431]
subset	PSI-MOD-slim
xref	DiffAvg: "236.40"
xref	DiffFormula: "C 16 H 28 N 0 O 1"
xref	DiffMono: "236.214016"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1424. MOD:01424 quinaldate modified residue

Table 1426. Term [MOD:01424]
id	MOD:01424
name	quinaldate modified residue
def	"A protein modification that effectively results from forming an adduct with a compound containing a quinaldate, kynurenate, or xanthurenate group." [PubMed:18688235]
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1425. MOD:01425 pyridinyl ring crosslinked residues

Table 1427. Term [MOD:01425]
id	MOD:01425
name	pyridinyl ring crosslinked residues
def	"A protein modification that crosslinks three residues by formation of a pyridinyl ring, such as pyridine-2,5-dicarboxylic acid or 5-aminopiperideine-2,5-dicarboxylic acid." [PubMed:18688235]
comment	Cross-link 3.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C, S, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1426. MOD:01426 isotope tagged reagent derivatized residue

Table 1428. Term [MOD:01426]
id	MOD:01426
name	isotope tagged reagent derivatized residue
def	"A protein modification that forms an adduct with a particular isotope labeled compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1427. MOD:01427 2-aminobutanoic acid (Abu)

Table 1429. Term [MOD:01427]
id	MOD:01427
name	2-aminobutanoic acid (Abu)
def	"OBSOLETE because redundant and identical to MOD:00819. Remap to MOD:00819." [PubMed:18688235]
synonym	"Abu" EXACT DeltaMass-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 4 H 7 N 1 O 1"
xref	MassAvg: "85.11"
xref	MassMono: "85.052764"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_obsolete	true

2.1428. MOD:01428 (13)C isotope tagged reagent

Table 1430. Term [MOD:01428]
id	MOD:01428
name	(13)C isotope tagged reagent
def	"A protein modification that forms an adduct with a (13)C labeled compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1429. MOD:01429 (15)N isotope tagged reagent

Table 1431. Term [MOD:01429]
id	MOD:01429
name	(15)N isotope tagged reagent
def	"A protein modification that forms an adduct with a (15)N labeled compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1430. MOD:01430 (18)O isotope tagged reagent

Table 1432. Term [MOD:01430]
id	MOD:01430
name	(18)O isotope tagged reagent
def	"A protein modification that forms an adduct with a (13)C labeled compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1431. MOD:01431 (2)H deuterium tagged reagent

Table 1433. Term [MOD:01431]
id	MOD:01431
name	(2)H deuterium tagged reagent
def	"A protein modification that forms an adduct with a (2)H labeled compound used as a reagent." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1432. MOD:01432 (2S,4S)-4,5-dihydroxyleucine

Table 1434. Term [MOD:01432]
id	MOD:01432
name	(2S,4S)-4,5-dihydroxyleucine
def	"A protein modification that effectively converts an L-leucine residue to a (2S,4S)-4,5-dihydroxyleucine." [PubMed:3718926, RESID:AA0446]
synonym	"(2S,4S)-2-amino-4,5-dihydroxy-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"(2S,4S)-4,5-dihydroxyleucine" EXACT RESID-name []
synonym	"(4S)-4,5-dihydroxyleucine" EXACT RESID-alternate []
synonym	"gamma,delta-dihydroxyleucine" EXACT RESID-alternate []
xref	DiffAvg: "32.00"
xref	DiffFormula: "C 0 H 0 N 0 O 2"
xref	DiffMono: "31.989829"
xref	Formula: "C 6 H 11 N 1 O 3"
xref	MassAvg: "145.16"
xref	MassMono: "145.073893"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01412 dihydroxylated leucine ! dihydroxylated leucine

2.1433. MOD:01433 1-amino-2-propanone

Table 1435. Term [MOD:01433]
id	MOD:01433
name	1-amino-2-propanone
def	"A protein modification that effectively converts an L-threonine residue into 1-amino-2-propanone." [ChEBI:17906, PubMed:12715872, PubMed:19196969, RESID:AA0486]
synonym	"1-amino-2-propanone" EXACT RESID-name []
synonym	"1-aminopropan-2-one" EXACT RESID-alternate []
synonym	"1-aminopropanone" EXACT RESID-systematic []
synonym	"aminoacetone" EXACT RESID-alternate []
synonym	"MOD_RES 1-amino-2-propanone" EXACT UniProt-feature []
xref	DiffAvg: "-46.03"
xref	DiffFormula: "C -1 H -2 N 0 O -2"
xref	DiffMono: "-46.005479"
xref	Formula: "C 3 H 6 N 1 O 1"
xref	MassAvg: "72.09"
xref	MassMono: "72.044939"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00683 dehydrogenated residue ! dehydrogenated residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00960 decarboxylated residue ! decarboxylated residue

2.1434. MOD:01434 4-hydroxy-L-glutamic acid

Table 1436. Term [MOD:01434]
id	MOD:01434
name	4-hydroxy-L-glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to a 4-hydroxy-L-glutamic acid." [PubMed:893891, RESID:AA0487]
synonym	"(2S,4Xi)-2-amino-4-hydroxypentanedioic acid" EXACT RESID-systematic []
synonym	"4-hydroxy-L-glutamic acid" EXACT RESID-name []
synonym	"gamma-hydroxy glutaminic acid" EXACT RESID-alternate []
synonym	"MOD_RES 4-hydroxyglutamate" EXACT UniProt-feature []
synonym	"threo-4-hydroxy-L-glutamic acid" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 4"
xref	MassAvg: "145.11"
xref	MassMono: "145.037508"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1435. MOD:01435 2-(cystein-S-ylcarbonyl)-3-methyl-4-(glutam-5-yloxy)methylindole

Table 1437. Term [MOD:01435]
id	MOD:01435
name	2-(cystein-S-ylcarbonyl)-3-methyl-4-(glutam-5-yloxy)methylindole
def	"A protein modification that effectively results from forming an adduct between a cysteine residue, a glutamic acid residue and the indole compound 2-carboxy-3-methyl-4-hydroxymethyl—indole." [PubMed:893891, RESID:AA0488]
comment	Cross-link 2.
synonym	"2-([(1R)-1-amino-1-carboxyeth-2-yl]sulfanyl)carbonyl-3-methyl-4-([(1S)-1-amino-1-carboxy-4-oxobutan-4-yl]oxy)methyl-1H-indole" EXACT RESID-systematic []
synonym	"2-(cystein-S-ylcarbonyl)-3-methyl-4-(glutam-5-yloxy)methylindole" EXACT RESID-name []
synonym	"2-(cystein-S-ylcarbonyl)-4-[(glutam-5-yloxy)methyl]-3-methyl-1H-indole" EXACT RESID-alternate []
synonym	"BINDING 3-methyl-4-hydroxymethylindole-2-carboxylic acid (covalent; via 2 links)" EXACT UniProt-feature []
xref	DiffAvg: "169.18"
xref	DiffFormula: "C 11 H 7 N 1 O 1 S 0"
xref	DiffMono: "169.052764"
xref	Formula: "C 19 H 19 N 3 O 5 S 1"
xref	MassAvg: "401.44"
xref	MassMono: "401.104542"
xref	Origin: "C, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00672 S-acylated residue ! S-acylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1436. MOD:01436 cyclo[(prolylserin)-O-yl] cysteinate (Cys)

Table 1438. Term [MOD:01436]
id	MOD:01436
name	cyclo[(prolylserin)-O-yl] cysteinate (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to cyclo[(prolylserin)-O-yl] cysteinate." [PubMed:7961166, RESID:AA0489#CYS]
synonym	"(3,6-dioxopyrrolo[4,5-a]piperazin-2-yl)methyl cysteinate" EXACT RESID-alternate []
synonym	"[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]methyl (2R)-2-amino-3-sulfanylpropanoate" EXACT RESID-systematic []
synonym	"cyclo[(prolylserin)-O-yl] cysteinate" EXACT RESID-name []
synonym	"MOD_RES Cyclo[(prolylserin)-O-yl] cysteinate" EXACT UniProt-feature []
xref	DiffAvg: "166.18"
xref	DiffFormula: "C 8 H 10 N 2 O 2 S 0"
xref	DiffMono: "166.074228"
xref	Formula: "C 11 H 16 N 3 O 4 S 1"
xref	MassAvg: "286.33"
xref	MassMono: "286.086152"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01629 cyclo[(prolylserin)-O-yl] cysteinate ! cyclo[(prolylserin)-O-yl] cysteinate

2.1437. MOD:01437 cyclo[(prolylserin)-O-yl] cysteinate (Cys-Pro-Ser cross-link)

Table 1439. Term [MOD:01437]
id	MOD:01437
name	cyclo[(prolylserin)-O-yl] cysteinate (Cys-Pro-Ser cross-link)
def	"A protein modification that effectively converts an L-cysteine residue, an L-proline residue, and an L-serine residue to cyclo[(prolylserin)-O-yl] cysteinate." [PubMed:7961166, RESID:AA0489#TRI]
comment	Cross-link 3.
synonym	"(3,6-dioxopyrrolo[4,5-a]piperazin-2-yl)methyl cysteinate" EXACT RESID-alternate []
synonym	"[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]methyl (2R)-2-amino-3-sulfanylpropanoate" EXACT RESID-systematic []
synonym	"cyclo[(prolylserin)-O-yl] cysteinate" EXACT RESID-name []
synonym	"MOD_RES Cyclo[(prolylserin)-O-yl] cysteinate" EXACT UniProt-feature []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 11 H 16 N 3 O 4 S 1"
xref	MassAvg: "286.33"
xref	MassMono: "286.086152"
xref	Origin: "C, P, S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01629 cyclo[(prolylserin)-O-yl] cysteinate ! cyclo[(prolylserin)-O-yl] cysteinate

2.1438. MOD:01438 S-[2-(pyridin-2-yl)ethyl]-L-cysteine

Table 1440. Term [MOD:01438]
id	MOD:01438
name	S-[2-(pyridin-2-yl)ethyl]-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-[2-(pyridin-2-yl)ethyl]-L-cysteine." [PubMed:18369855, PubMed:18688235]
comment	From DeltaMass: (name misspelled "Pyridylethyl Cystenyl", and formula incorrect, N and O reversed) Formula: C10H12O2N1S1 Monoisotopic Mass Change: 208.067 Average Mass Change: 208.286
synonym	"2-PEC" EXACT PSI-MOD-alternate []
synonym	"2-vinylpyridine derivatized cysteine residue" EXACT PSI-MOD-alternate []
synonym	"Pyridylethyl" RELATED PSI-MS-label []
synonym	"Pyridylethyl Cystenyl" EXACT DeltaMass-label []
synonym	"S-(pyridin-2-ylethyl)-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-pyridylethylation" RELATED UniMod-description []
xref	DiffAvg: "105.14"
xref	DiffFormula: "C 7 H 7 N 1"
xref	DiffMono: "105.057849"
xref	Formula: "C 10 H 12 N 2 O 1 S 1"
xref	MassAvg: "208.28"
xref	MassMono: "208.067034"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00424 S-pyridylethyl-L-cysteine ! S-pyridylethyl-L-cysteine

2.1439. MOD:01439 S-[2-(pyridin-4-yl)ethyl]-L-cysteine

Table 1441. Term [MOD:01439]
id	MOD:01439
name	S-[2-(pyridin-4-yl)ethyl]-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-[2-(pyridin-4-yl)ethyl]-L-cysteine." [PubMed:18688235, PubMed:6528972]
synonym	"4-PEC" EXACT PSI-MOD-alternate []
synonym	"Pyridylethyl" RELATED PSI-MS-label []
synonym	"Pyridylethyl Cystenyl" EXACT DeltaMass-label []
synonym	"S-(pyridin-4-ylethyl)-L-cysteine" EXACT PSI-MOD-alternate []
synonym	"S-pyridylethylation" RELATED UniMod-description []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00424 S-pyridylethyl-L-cysteine ! S-pyridylethyl-L-cysteine

2.1440. MOD:01440 glutamyl semialdehyde

Table 1442. Term [MOD:01440]
id	MOD:01440
name	glutamyl semialdehyde
def	"A protein modification that effectively converts a source amino acid residue to an L-glutamyl semialdehyde." [PubMed:18688235]
synonym	"(S)-2-amino-5-oxopentanoic acid" EXACT PSI-MOD-alternate []
synonym	"L-glutamic gamma-semialdehyde" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1441. MOD:01441 natural, standard, encoded residue

Table 1443. Term [MOD:01441]
id	MOD:01441
name	natural, standard, encoded residue
def	"A protein modification that inserts or replaces a residue with a natural, standard, encoded residue." [PubMed:18688235, PubMed:6692818]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00009 natural residue ! natural residue

2.1442. MOD:01442 3-(O4'-L-tyrosyl)-L-valine

Table 1444. Term [MOD:01442]
id	MOD:01442
name	3-(O4'-L-tyrosyl)-L-valine
def	"A protein modification that effectively cross-links an L-valine residue and an L-tyrosine residue by an ether bond to form 3-(O4'-L-tyrosyl)-L-valine." [PubMed:19321420, RESID:AA0490]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-(4-[(2S)-2-amino-2-carboxyethyl]phenoxy)-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"3-(O4'-L-tyrosyl)-L-valine" EXACT RESID-name []
synonym	"CROSSLNK 3-(O4'-tyrosyl)-valine (Val-Tyr)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 14 H 16 N 2 O 3"
xref	MassAvg: "260.29"
xref	MassMono: "260.116092"
xref	Origin: "V, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue

2.1443. MOD:01443 tetrakis-L-glutamato bis-L-N1'-histidino lipid carboxylato manganese iron oxide

Table 1445. Term [MOD:01443]
id	MOD:01443
name	tetrakis-L-glutamato bis-L-N1'-histidino lipid carboxylato manganese iron oxide
def	"A protein modification that effectively converts four L-glutamic acid residues and two L-histidine residues to tetrakis-L-glutamato bis-L-N1'-histidino lipid carboxylato manganese iron oxide." [PubMed:19321420, RESID:AA0491]
comment	Cross-link 6. It is not clear whether the lipid carboxylate is a cofactor or a substrate, and its identity is not certain. It was modeled as myristic acid [JSG].
xref	DiffAvg: "350.12"
xref	DiffFormula: "C 14 Fe 1 H 23 Mn 1 N 0 O 3"
xref	DiffMono: "350.038251"
xref	FormalCharge: "1-"
xref	Formula: "C 46 Fe 1 H 65 Mn 1 N 10 O 17"
xref	MassAvg: "1140.86"
xref	MassMono: "1140.326447"
xref	Origin: "E, E, E, E, H, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00438 myristoylated residue ! myristoylated residue
is_a	MOD:00738 iron containing modified residue ! iron containing modified residue
is_a	MOD:00740 manganese containing modified residue ! manganese containing modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue

2.1444. MOD:01444 L-3,3-dihydroxyoalanine (Cys)

Table 1446. Term [MOD:01444]
id	MOD:01444
name	L-3,3-dihydroxyoalanine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to L-3,3-dihydroxyoalanine." [PubMed:11435113, PubMed:17558559, RESID:AA0492#CYS]
synonym	"(S)-2-amino-3,3-dihydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-(dihydroxymethyl)glycine" EXACT RESID-alternate []
synonym	"3,3-dihydroxy-L-alanine" EXACT RESID-name []
synonym	"3,3-dihydroxyalanine" EXACT RESID-alternate []
synonym	"3-hydroxy-L-serine" EXACT RESID-alternate []
synonym	"3-oxoalanine hydrate" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine hydrate" RELATED RESID-misnomer []
xref	DiffAvg: "-0.06"
xref	DiffFormula: "C 0 H 0 N 0 O 2 S -1"
xref	DiffMono: "0.017758"
xref	Formula: "C 3 H 5 N 1 O 3"
xref	MassAvg: "103.08"
xref	MassMono: "103.026943"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01448 L-3,3-dihydroxyoalanine ! L-3,3-dihydroxyoalanine

2.1445. MOD:01445 L-3,3-dihydroxyoalanine (Ser)

Table 1447. Term [MOD:01445]
id	MOD:01445
name	L-3,3-dihydroxyoalanine (Ser)
def	"A protein modification that effectively converts an L-serine residue to L-3,3-dihydroxyoalanine." [PubMed:11435113, PubMed:17558559, RESID:AA0492#SER]
synonym	"(S)-2-amino-3,3-dihydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-(dihydroxymethyl)glycine" EXACT RESID-alternate []
synonym	"3,3-dihydroxy-L-alanine" EXACT RESID-name []
synonym	"3,3-dihydroxyalanine" EXACT RESID-alternate []
synonym	"3-hydroxy-L-serine" EXACT RESID-alternate []
synonym	"3-oxoalanine hydrate" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine hydrate" RELATED RESID-misnomer []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 3 H 5 N 1 O 3"
xref	MassAvg: "103.08"
xref	MassMono: "103.026943"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01448 L-3,3-dihydroxyoalanine ! L-3,3-dihydroxyoalanine

2.1446. MOD:01446 N-(dihydroxymethyl)-L-methionine (fMet)

Table 1448. Term [MOD:01446]
id	MOD:01446
name	N-(dihydroxymethyl)-L-methionine (fMet)
def	"A protein modification that effectively converts an N-formyl-Lmethionine residue to N-(dihydroxymethyl)-L-methionine." [PubMed:12595263, PubMed:9159480, RESID:AA0493]
synonym	"(2S)-2-[(dihydroxymethyl)amino]-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"N-(dihydroxymethyl)-L-methionine" EXACT RESID-name []
synonym	"N-formyl-L-methionine hydrate" EXACT RESID-alternate []
synonym	"N-orthoformylmethionine" EXACT RESID-alternate []
xref	DiffAvg: "18.02"
xref	DiffFormula: "C 0 H 2 N 0 O 1 S 0"
xref	DiffMono: "18.010565"
xref	Formula: "C 6 H 12 N 1 O 3 S 1"
xref	MassAvg: "178.23"
xref	MassMono: "178.053789"
xref	Origin: "MOD:00030"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:01450 modified N-formyl-L-methionine residue ! modified N-formyl-L-methionine residue
relationship	derives_from MOD:00030 N-formyl-L-methionine residue ! N-formyl-L-methionine residue

2.1447. MOD:01447 N-(dihydroxymethyl)-L-methionine (Met)

Table 1449. Term [MOD:01447]
id	MOD:01447
name	N-(dihydroxymethyl)-L-methionine (Met)
def	"A protein modification that effectively converts an L-methionine residue to N-(dihydroxymethyl)-L-methionine (not known as a natural, post-translational modification process)." [PubMed:12595263, PubMed:9159480, RESID:AA0493]
comment	This entry is for the artifactual formation of N-(dihydroxymethyl)-L-methionine from methionine. For N-(dihydroxymethyl)-L-methionine derived from encoded N-formyl-L-methionine, use MOD:01446.
synonym	"(2S)-2-[(dihydroxymethyl)amino]-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"N-(dihydroxymethyl)-L-methionine" EXACT RESID-name []
synonym	"N-formyl-L-methionine hydrate" EXACT RESID-alternate []
synonym	"N-orthoformylmethionine" EXACT RESID-alternate []
xref	DiffAvg: "46.03"
xref	DiffFormula: "C 1 H 2 N 0 O 2 S 0"
xref	DiffMono: "46.005479"
xref	Formula: "C 6 H 12 N 1 O 3 S 1"
xref	MassAvg: "178.23"
xref	MassMono: "178.053789"
xref	Origin: "M"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.1448. MOD:01448 L-3,3-dihydroxyoalanine

Table 1450. Term [MOD:01448]
id	MOD:01448
name	L-3,3-dihydroxyoalanine
def	"A protein modification that effectively converts a source amino acid residue to L-3,3-dihydroxyoalanine." [PubMed:11435113, PubMed:17558559, RESID:AA0492]
synonym	"(S)-2-amino-3,3-dihydroxypropanoic acid" EXACT RESID-systematic []
synonym	"2-(dihydroxymethyl)glycine" EXACT RESID-alternate []
synonym	"3,3-dihydroxy-L-alanine" EXACT RESID-name []
synonym	"3,3-dihydroxyalanine" EXACT RESID-alternate []
synonym	"3-hydroxy-L-serine" EXACT RESID-alternate []
synonym	"3-oxoalanine hydrate" EXACT RESID-alternate []
synonym	"C(alpha)-formylglycine hydrate" RELATED RESID-misnomer []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 3 H 5 N 1 O 3"
xref	MassAvg: "103.08"
xref	MassMono: "103.026943"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1449. MOD:01449 L-3,3-dihydroxyoalanine (Oxoalanine)

Table 1451. Term [MOD:01449]
id	MOD:01449
name	L-3,3-dihydroxyoalanine (Oxoalanine)
def	"A protein modification that effectively converts an L-3-oxoalanine residue to L-3,3-dihydroxyoalanine." [PubMed:11435113, PubMed:17558559, PubMed:18688235]
xref	DiffAvg: "18.02"
xref	DiffFormula: "C 0 H 2 N 0 O 1"
xref	DiffMono: "18.010565"
xref	Formula: "C 3 H 5 N 1 O 3"
xref	MassAvg: "103.08"
xref	MassMono: "103.026943"
xref	Origin: "MOD:01169"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01448 L-3,3-dihydroxyoalanine ! L-3,3-dihydroxyoalanine
relationship	derives_from MOD:01169 L-3-oxoalanine ! L-3-oxoalanine

2.1450. MOD:01450 modified N-formyl-L-methionine residue

Table 1452. Term [MOD:01450]
id	MOD:01450
name	modified N-formyl-L-methionine residue
def	"A protein modification that modifies an N-formyl-L-methionine residue." [PubMed:18688235]
xref	Origin: "MOD:00030"
xref	TermSpec: "N-term"
is_a	MOD:01157 protein modification categorized by amino acid modified ! protein modification categorized by amino acid modified
relationship	derives_from MOD:00030 N-formyl-L-methionine residue ! N-formyl-L-methionine residue

2.1451. MOD:01451 O-phospho-L-serine arising from O-phosphopantetheine-L-serine after neutral loss of pantetheine

Table 1453. Term [MOD:01451]
id	MOD:01451
name	O-phospho-L-serine arising from O-phosphopantetheine-L-serine after neutral loss of pantetheine
def	"A protein modification that converts an L-serine residue to O-phosphopantetheine-L-serine with secondary neutral loss of pantetheine resulting in O-phospho-L-serine." [PubMed:17042494, PubMed:18688235]
comment	Phosphoserine is generated and detected after the facile elimination of pantetheine from the phosphopantetheine tertiary phosphodiester. See MOD:01452 for alternate origin.
subset	PSI-MOD-slim
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 3 H 6 N 1 O 5 P 1"
xref	MassAvg: "167.06"
xref	MassMono: "166.998359"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00046 O-phospho-L-serine ! O-phospho-L-serine
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
relationship	derives_from MOD:00159 O-phosphopantetheine-L-serine ! O-phosphopantetheine-L-serine

2.1452. MOD:01452 O-phosphopantetheine-L-serine with neutral loss of pantetheine

Table 1454. Term [MOD:01452]
id	MOD:01452
name	O-phosphopantetheine-L-serine with neutral loss of pantetheine
def	"Covalent modification of a peptide or protein amino acid O-phosphopantetheine-L-serine with secondary neutral loss of pantetheine resulting in O-phospho-L-serine." [PubMed:17042494, PubMed:18688235]
comment	Phosphoserine is generated and detected after the facile elimination of pantethiene from the phosphopantethiene tertiary phosphodiester. See MOD:01451 for alternate origin.
subset	PSI-MOD-slim
xref	DiffAvg: "-260.35"
xref	DiffFormula: "C -11 H -20 N -2 O -3 P 0 S -1"
xref	DiffMono: "-260.119464"
xref	Formula: "C 3 H 6 N 1 O 5 P 1"
xref	MassAvg: "167.06"
xref	MassMono: "166.998359"
xref	Origin: "MOD:00159"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00046 O-phospho-L-serine ! O-phospho-L-serine
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
relationship	derives_from MOD:00159 O-phosphopantetheine-L-serine ! O-phosphopantetheine-L-serine

2.1453. MOD:01453 L-glutamic acid 5-methyl ester

Table 1455. Term [MOD:01453]
id	MOD:01453
name	L-glutamic acid 5-methyl ester
def	"A protein modification that effectively converts a source amino acid residue to L-glutamate 5-methyl ester." [RESID:AA0072]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-5-methoxy-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(5)-methyl L-hydrogen glutamate" EXACT RESID-alternate []
synonym	"2-aminopentanedioic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"5-methyl esterified L-glutamic acid" EXACT PSI-MOD-alternate []
synonym	"5-methyl L-2-aminoglutarate" EXACT RESID-alternate []
synonym	"5-methyl L-glutamate" EXACT RESID-alternate []
synonym	"glutamic acid 5-methyl ester" EXACT RESID-alternate []
synonym	"glutamic acid gamma-methyl ester" EXACT RESID-alternate []
synonym	"L-glutamic acid 5-methyl ester" EXACT RESID-name []
synonym	"O-methyl Glutamyl" EXACT DeltaMass-label []
synonym	"O5MeGlu" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 9 N 1 O 3"
xref	MassAvg: "143.14"
xref	MassMono: "143.058243"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00393 O-methylated residue ! O-methylated residue
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00713 methylated glutamic acid ! methylated glutamic acid
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1454. MOD:01454 N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-prolinium

Table 1456. Term [MOD:01454]
id	MOD:01454
name	N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-prolinium
def	"A protein modification that effectively crosslinks an N-terminal L-proline residue and a strand of DNA at the C-1 of a ribose, freeing the nucleotide base and forming N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-prolinium." [PubMed:10833024, PubMed:11847126, PubMed:9030608, RESID:AA0494]
comment	This linkage is not a Schiff-base [JSG].
synonym	"(1Z,2S)-2-carboxy-1-[(3R,4R)-3,4-dihydroxy-5-(phosphonooxy)pentylidene]pyrrolidinium" EXACT RESID-systematic []
synonym	"DNA glycosylase proline Schiff base intermediate" RELATED RESID-misnomer []
synonym	"N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-prolinium" EXACT RESID-name []
xref	DiffAvg: "179.09"
xref	DiffFormula: "C 5 H 8 N 0 O 5 P 1"
xref	DiffMono: "179.010386"
xref	FormalCharge: "1+"
xref	Formula: "C 10 H 16 N 1 O 6 P 1"
xref	MassAvg: "277.21"
xref	MassMono: "277.070975"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue

2.1455. MOD:01455 O-phosphorylated residue

Table 1457. Term [MOD:01455]
id	MOD:01455
name	O-phosphorylated residue
def	"A protein modification that effectively replaces a residue hydroxyl or carboxyl hydrogen with a phosphono group (H2PO3 or 'phosphate')." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OPhosRes" EXACT PSI-MOD-label []
xref	DiffAvg: "79.98"
xref	DiffFormula: "H 1 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00696 phosphorylated residue ! phosphorylated residue

2.1456. MOD:01456 N-phosphorylated residue

Table 1458. Term [MOD:01456]
id	MOD:01456
name	N-phosphorylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue amino or imino group with a phosphono group (H2PO3 or 'phosphate')." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OPhosRes" EXACT PSI-MOD-label []
xref	DiffAvg: "79.98"
xref	DiffFormula: "H 1 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00696 phosphorylated residue ! phosphorylated residue

2.1457. MOD:01457 L-cysteine (Ser)

Table 1459. Term [MOD:01457]
id	MOD:01457
name	L-cysteine (Ser)
def	"A protein modification that effectively converts an L-serine residue to L-cysteine (not known as a natural, post-translational modification process)." [PubMed:1849824, PubMed:18688235]
synonym	"Cys(Ser)" EXACT PSI-MOD-label []
xref	DiffAvg: "-16.06"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S -1"
xref	DiffMono: "-15.977156"
xref	Formula: "C 3 H 5 N 1 O 1 S 1"
xref	MassAvg: "103.14"
xref	MassMono: "103.009185"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00014 L-cysteine residue ! L-cysteine residue
is_a	MOD:00749 sulfur substitution for oxygen ! sulfur substitution for oxygen
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1458. MOD:01458 alpha-amino acetylated residue

Table 1460. Term [MOD:01458]
id	MOD:01458
name	alpha-amino acetylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an acetyl group." [OMSSA:10, UniMod:1#N-term]
subset	PSI-MOD-slim
synonym	"N2AcRes" EXACT PSI-MOD-label []
synonym	"ntermacetyl" EXACT OMSSA-label []
xref	DiffAvg: "42.04"
xref	DiffFormula: "C 2 H 2 N 0 O 1"
xref	DiffMono: "42.010565"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00408 N-acetylated residue ! N-acetylated residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1459. MOD:01459 4x(2)H labeled alpha-dimethylamino N-terminal residue

Table 1461. Term [MOD:01459]
id	MOD:01459
name	4x(2)H labeled alpha-dimethylamino N-terminal residue
def	"A protein modification that effectively converts an N-terminal residue to an 4x(2)H labeled alpha-dimethylamino N-terminal residue." [OMSSA:190, PubMed:14670044, UniMod:199#N-term]
comment	Supposed to be alpha-amino and Lys-N6 derivatized by C(2)H2O and reduction.
subset	PSI-MOD-slim
synonym	"DiMethyl-CHD2" RELATED UniMod-description []
synonym	"Dimethyl:2H(4)" RELATED PSI-MS-label []
synonym	"mod190" EXACT OMSSA-label []
xref	DiffAvg: "32.06"
xref	DiffFormula: "C 2 (2)H 4"
xref	DiffMono: "32.056407"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00552 4x(2)H labeled dimethylated residue ! 4x(2)H labeled dimethylated residue

2.1460. MOD:01460 alpha-amino methylated residue

Table 1462. Term [MOD:01460]
id	MOD:01460
name	alpha-amino methylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"N2MeRes" EXACT PSI-MOD-label []
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00602 N-methylated residue ! N-methylated residue

2.1461. MOD:01461 N-methylated alanine

Table 1463. Term [MOD:01461]
id	MOD:01461
name	N-methylated alanine
def	"A protein modification that effectively replaces an L-alanine alpha amino hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00665 methylated alanine ! methylated alanine
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1462. MOD:01462 N-methylated proline

Table 1464. Term [MOD:01462]
id	MOD:01462
name	N-methylated proline
def	"A protein modification that effectively replaces an L-proline alpha imino hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00712 methylated proline ! methylated proline
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1463. MOD:01463 N-methylated methionine

Table 1465. Term [MOD:01463]
id	MOD:01463
name	N-methylated methionine
def	"A protein modification that effectively replaces an L-methionine alpha amino hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00716 methylated methionine ! methylated methionine
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1464. MOD:01464 protonated L-methionine (L-methioninium) residue

Table 1466. Term [MOD:01464]
id	MOD:01464
name	protonated L-methionine (L-methioninium) residue
def	"A protein modification that effectively converts an L-methionine residue to an L-methioninium (protonated L-methionine)." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0 S 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 11 N 1 O 1 S 1"
xref	MassAvg: "133.21"
xref	MassMono: "133.055586"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.1465. MOD:01465 N,N,N-trimethyl-L-methionine (from L-methioninium)

Table 1467. Term [MOD:01465]
id	MOD:01465
name	N,N,N-trimethyl-L-methionine (from L-methioninium)
def	"A protein modification that effectively converts an L-methioninium (protonated L-methionine) residue to an N6,N6,N6-trimethyl-L-methionine." [PubMed:18688235]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N2Me3+Met process (MOD:01382) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N2Me3Met" EXACT PSI-MOD-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0 S 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 17 N 1 O 1 S 1"
xref	MassAvg: "175.29"
xref	MassMono: "175.102537"
xref	Origin: "MOD:001464"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01687 alpha-amino trimethylated residue ! alpha-amino trimethylated residue
relationship	derives_from MOD:01464 protonated L-methionine (L-methioninium) residue ! protonated L-methionine (L-methioninium) residue

2.1466. MOD:01466 menadione quinone derivative - site C

Table 1468. Term [MOD:01466]
id	MOD:01466
name	menadione quinone derivative - site C
def	"modification from UniMod Chemical derivative" [PubMed:15939799, UniMod:302#K]
synonym	"Menadione" RELATED UniMod-interim []
synonym	"Menadione quinone derivative" RELATED UniMod-description []
xref	DiffAvg: "170.17"
xref	DiffFormula: "C 11 H 6 O 2"
xref	DiffMono: "170.036779"
xref	Formula: "C 14 H 11 N 1 O 3 S 1"
xref	MassAvg: "273.31"
xref	MassMono: "273.045964"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00621 menadione quinone derivative ! menadione quinone derivative
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1467. MOD:01467 menadione quinone derivative - site K

Table 1469. Term [MOD:01467]
id	MOD:01467
name	menadione quinone derivative - site K
def	"modification from UniMod Chemical derivative" [PubMed:15939799, UniMod:302#K]
synonym	"Menadione" RELATED UniMod-interim []
synonym	"Menadione quinone derivative" RELATED UniMod-description []
xref	DiffAvg: "170.17"
xref	DiffFormula: "C 11 H 6 O 2"
xref	DiffMono: "170.036779"
xref	Formula: "C 17 H 18 N 2 O 3"
xref	MassAvg: "298.34"
xref	MassMono: "298.131742"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00621 menadione quinone derivative ! menadione quinone derivative
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1468. MOD:01468 L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) (Cys)

Table 1470. Term [MOD:01468]
id	MOD:01468
name	L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) (not known as a natural, post-translational modification process)." [PubMed:14235557, PubMed:2211698, PubMed:8052647, PubMed:9036855, RESID:AA0248#CYS, UniMod:415]
comment	This entry is for the artifactual formation of L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) from cysteine. For natural formation from L-selenocysteine, use MOD:00253.
synonym	"2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotide" EXACT RESID-alternate []
synonym	"bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-selenocysteinyl-Se-molybdenum" EXACT RESID-systematic []
synonym	"formate dehydrogenase selenocysteine molybdenum cofactor" EXACT RESID-alternate []
synonym	"L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)" RELATED UniMod-description []
synonym	"L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)" EXACT RESID-name []
synonym	"molybdopterin-se" RELATED UniMod-interim []
synonym	"MolybdopterinGD+Delta:S(-1)Se(1)" RELATED PSI-MS-label []
xref	DiffAvg: "1618.93"
xref	DiffFormula: "C 40 H 47 Mo 1 N 20 O 26 P 4 S 3 Se 1"
xref	DiffMono: "1620.930226"
xref	Formula: "C 43 H 52 Mo 1 N 21 O 27 P 4 S 4 Se 1"
xref	MassAvg: "1722.07"
xref	MassMono: "1723.939410"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00744 molybdenum pterin containing modification ! molybdenum pterin containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1469. MOD:01469 L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) (Cys)

Table 1471. Term [MOD:01469]
id	MOD:01469
name	L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) (not known as a natural, post-translational modification process)." [PubMed:11372198, PubMed:12220497, RESID:AA0376#CYS]
comment	This entry is for the artifactual formation of L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) from cysteine. For natural formation from L-selenocysteine, use MOD:00381.
xref	DiffAvg: "1738.88"
xref	DiffFormula: "C 40 H 47 N 20 O 26 P 4 S 4 Se 1 W 1"
xref	DiffMono: "1738.947820"
xref	Formula: "C 43 H 52 N 21 O 27 P 4 S 5 Se 1 W 1"
xref	MassAvg: "1842.02"
xref	MassMono: "1841.957004"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00746 tungsten containing modified residue ! tungsten containing modified residue
is_a	MOD:00748 pterin modified residue ! pterin modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1470. MOD:01470 (E)-dehydrobutyrine (Thr)

Table 1472. Term [MOD:01470]
id	MOD:01470
name	(E)-dehydrobutyrine (Thr)
def	"A protein modification that effectively converts an L-threonine residue to (E)-dehydrobutyrine." [DeltaMass:0, PubMed:1547888, PubMed:20805503, PubMed:3769923, RESID:AA0547]
subset	PSI-MOD-slim
synonym	"(2E)-2-aminobut-2-enoic acid" EXACT RESID-systematic []
synonym	"(E)-2-amino-2-butenoic acid" EXACT RESID-alternate []
synonym	"(E)-2-aminobutenoic acid" EXACT RESID-alternate []
synonym	"(E)-dehydrobutyrine" EXACT RESID-name []
synonym	"(E)dHAbu" EXACT PSI-MOD-label []
synonym	"2,3-didehydrobutyrine" EXACT RESID-alternate []
synonym	"3-methyldehydroalanine" EXACT RESID-alternate []
synonym	"alpha,beta-dehydroaminobutyric acid" EXACT RESID-alternate []
synonym	"anhydrothreonine" EXACT RESID-alternate []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"Dehydroamino butyric acid" EXACT DeltaMass-label []
synonym	"Dhb" EXACT RESID-alternate []
synonym	"methyl-dehydroalanine" EXACT RESID-alternate []
synonym	"MOD_RES (E)-2,3-didehydrobutyrine" EXACT UniProt-feature []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00190 dehydrobutyrine (Thr) ! dehydrobutyrine (Thr)

2.1471. MOD:01471 (Z)-dehydrobutyrine (Thr)

Table 1473. Term [MOD:01471]
id	MOD:01471
name	(Z)-dehydrobutyrine (Thr)
def	"A protein modification that effectively converts an L-threonine residue to (Z)-dehydrobutyrine." [DeltaMass:0, PubMed:1547888, PubMed:3769923, RESID:AA0182]
subset	PSI-MOD-slim
synonym	"(2Z)-2-aminobut-2-enoic acid" EXACT RESID-systematic []
synonym	"(Z)-2-amino-2-butenoic acid" EXACT RESID-alternate []
synonym	"(Z)-2-aminobutenoic acid" EXACT RESID-alternate []
synonym	"(Z)-dehydrobutyrine" EXACT RESID-name []
synonym	"(Z)dHAbu" EXACT PSI-MOD-label []
synonym	"2,3-didehydrobutyrine" EXACT RESID-alternate []
synonym	"3-methyldehydroalanine" EXACT RESID-alternate []
synonym	"alpha,beta-dehydroaminobutyric acid" EXACT RESID-alternate []
synonym	"anhydrothreonine" EXACT RESID-alternate []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"Dehydroamino butyric acid" EXACT DeltaMass-label []
synonym	"Dhb" EXACT RESID-alternate []
synonym	"methyl-dehydroalanine" EXACT RESID-alternate []
synonym	"MOD_RES (Z)-2,3-didehydrobutyrine" EXACT UniProt-feature []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00190 dehydrobutyrine (Thr) ! dehydrobutyrine (Thr)

2.1472. MOD:01472 reduced residue

Table 1474. Term [MOD:01472]
id	MOD:01472
name	reduced residue
def	"A protein modification that effectively either adds neutral hydrogen atoms (proton and electron), or removes oxygen atoms from a residue with or without the addition of hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"RedRes" EXACT PSI-MOD-label []
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1473. MOD:01473 hydrogenated residue

Table 1475. Term [MOD:01473]
id	MOD:01473
name	hydrogenated residue
def	"A protein modification that effectively adds neutral hydrogen atoms (proton and electron) to a residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"HRes" EXACT PSI-MOD-label []
is_a	MOD:01472 reduced residue ! reduced residue

2.1474. MOD:01474 O-[S-(carboxymethyl)phosphopantetheine]-L-serine

Table 1476. Term [MOD:01474]
id	MOD:01474
name	O-[S-(carboxymethyl)phosphopantetheine]-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-[S-(carboxymethyl)phosphopantetheine]-L-serine." [PubMed:18688235]
comment	This modification results from the derivatization of the pantetheine sulfhydryl with iodoacetic acid [JSG].
xref	DiffAvg: "398.37"
xref	DiffFormula: "C 13 H 23 N 2 O 8 P 1 S 1"
xref	DiffMono: "398.091273"
xref	Formula: "C 16 H 28 N 3 O 10 P 1 S 1"
xref	MassAvg: "485.44"
xref	MassMono: "485.123302"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
relationship	derives_from MOD:00159 O-phosphopantetheine-L-serine ! O-phosphopantetheine-L-serine

2.1475. MOD:01475 O-[S-(carboxamidomethyl)phosphopantetheine]-L-serine

Table 1477. Term [MOD:01475]
id	MOD:01475
name	O-[S-(carboxamidomethyl)phosphopantetheine]-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-[S-(carboxamidomethyl)phosphopantetheine]-L-serine." [PubMed:18688235]
comment	This modification results from the derivatization of the pantetheine sulfhydryl with iodoacetamide [JSG].
xref	DiffAvg: "397.38"
xref	DiffFormula: "C 13 H 24 N 3 O 7 P 1 S 1"
xref	DiffMono: "397.107258"
xref	Formula: "C 16 H 29 N 4 O 9 P 1 S 1"
xref	MassAvg: "484.46"
xref	MassMono: "484.139286"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
relationship	derives_from MOD:00159 O-phosphopantetheine-L-serine ! O-phosphopantetheine-L-serine

2.1476. MOD:01476 2'-fluoro-L-phenylalanine

Table 1478. Term [MOD:01476]
id	MOD:01476
name	2'-fluoro-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to an 2'-fluoro-L-fluorophenylalanine." [PubMed:18688235, PubMed:8172898]
synonym	"2-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"o-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"ortho-fluorophenylalanine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "C 0 F 1 H -1 N 0 O 0"
xref	DiffMono: "17.990578"
xref	Formula: "C 9 F 1 H 8 N 1 O 1"
xref	MassAvg: "165.17"
xref	MassMono: "165.058992"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01227 monofluorinated L-phenylalanine ! monofluorinated L-phenylalanine

2.1477. MOD:01477 3'-fluoro-L-phenylalanine

Table 1479. Term [MOD:01477]
id	MOD:01477
name	3'-fluoro-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue to an 3'-fluoro-L-fluorophenylalanine." [PubMed:18688235, PubMed:8172898]
synonym	"3-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"m-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"meta-fluorophenylalanine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "C 0 F 1 H -1 N 0 O 0"
xref	DiffMono: "17.990578"
xref	Formula: "C 9 F 1 H 8 N 1 O 1"
xref	MassAvg: "165.17"
xref	MassMono: "165.058992"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01227 monofluorinated L-phenylalanine ! monofluorinated L-phenylalanine

2.1478. MOD:01478 4'-fluoro-L-phenylalanine

Table 1480. Term [MOD:01478]
id	MOD:01478
name	4'-fluoro-L-phenylalanine
def	"A protein modification that effectively converts an L-phenylalanine residue into an 4'-fluoro-L-fluorophenylalanine." [PubMed:18688235, PubMed:8172898]
synonym	"4-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"p-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"para-fluorophenylalanine" EXACT PSI-MOD-alternate []
synonym	"rho-fluorophenylalanine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "C 0 F 1 H -1 N 0 O 0"
xref	DiffMono: "17.990578"
xref	Formula: "C 9 F 1 H 8 N 1 O 1"
xref	MassAvg: "165.17"
xref	MassMono: "165.058992"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01227 monofluorinated L-phenylalanine ! monofluorinated L-phenylalanine

2.1479. MOD:01479 4'-fluoro-L-tryptophan

Table 1481. Term [MOD:01479]
id	MOD:01479
name	4'-fluoro-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue into an 4'-fluoro-L-tryptophan." [PubMed:18688235, PubMed:8172898]
synonym	"4-fluorotryptophan" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "F 1 H -1"
xref	DiffMono: "17.990578"
xref	Formula: "C 11 F 1 H 9 N 2 O 1"
xref	MassAvg: "204.20"
xref	MassMono: "204.069891"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01226 monofluorinated L-tryptophan ! monofluorinated L-tryptophan

2.1480. MOD:01480 5'-fluoro-L-tryptophan

Table 1482. Term [MOD:01480]
id	MOD:01480
name	5'-fluoro-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue into an 5'-fluoro-L-tryptophan." [PubMed:18688235, PubMed:8172898]
synonym	"5-fluorotryptophan" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "F 1 H -1"
xref	DiffMono: "17.990578"
xref	Formula: "C 11 F 1 H 9 N 2 O 1"
xref	MassAvg: "204.20"
xref	MassMono: "204.069891"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01226 monofluorinated L-tryptophan ! monofluorinated L-tryptophan

2.1481. MOD:01481 6'-fluoro-L-tryptophan

Table 1483. Term [MOD:01481]
id	MOD:01481
name	6'-fluoro-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue into an 6'-fluoro-L-tryptophan." [PubMed:18688235, PubMed:8172898]
synonym	"6-fluorotryptophan" EXACT PSI-MOD-alternate []
xref	DiffAvg: "17.99"
xref	DiffFormula: "F 1 H -1"
xref	DiffMono: "17.990578"
xref	Formula: "C 11 F 1 H 9 N 2 O 1"
xref	MassAvg: "204.20"
xref	MassMono: "204.069891"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01226 monofluorinated L-tryptophan ! monofluorinated L-tryptophan

2.1482. MOD:01482 calcium containing modified residue

Table 1484. Term [MOD:01482]
id	MOD:01482
name	calcium containing modified residue
def	"A protein modification that effectively substitutes a calcium atom or a cluster containing calcium for hydrogen atoms, or that coordinates a calcium ion." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"CaRes" EXACT PSI-MOD-label []
is_a	MOD:00698 metal or metal cluster containing modified residue ! metal or metal cluster containing modified residue

2.1483. MOD:01483 O-formylated residue

Table 1485. Term [MOD:01483]
id	MOD:01483
name	O-formylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a formyloxy group." [PubMed:18688235]
synonym	"OFoRes" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00493 formylated residue ! formylated residue
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.1484. MOD:01484 N6-(L-isoglutamyl)-L-lysine (Glu)

Table 1486. Term [MOD:01484]
id	MOD:01484
name	N6-(L-isoglutamyl)-L-lysine (Glu)
def	"A protein modification that effectively crosslinks an L-glutamic acid residue and an L-lysine residue by an isopeptide bond to form N6-(L-isoglutamyl)-L-lysine and the release of water." [ChEBI:21863, PubMed:19015515, RESID:AA0124#GLU]
comment	Cross-link 2. This cross-link is usually made by glutamine and releases ammonia, rather than glutamic acid and requiring the consumption of ATP.
synonym	"(2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acid" EXACT RESID-alternate []
synonym	"5-glutamyl N6-lysine" EXACT RESID-alternate []
synonym	"N alpha -(gamma-Glutamyl)-lysine" EXACT DeltaMass-label []
synonym	"N(epsilon)-(gamma-glutamyl)lysine" EXACT RESID-alternate []
synonym	"N6-(L-isoglutamyl)-L-lysine" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 11 H 17 N 3 O 3"
xref	MassAvg: "239.27"
xref	MassMono: "239.126991"
xref	Origin: "K, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01630 N6-(L-isoglutamyl)-L-lysine ! N6-(L-isoglutamyl)-L-lysine

2.1485. MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue

Table 1487. Term [MOD:01485]
id	MOD:01485
name	iTRAQ4plex-114 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [UniMod:532]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 114" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ114" RELATED UniMod-interim []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01430 (18)O isotope tagged reagent ! (18)O isotope tagged reagent
is_a	MOD:01516 modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da. ! modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da.
is_a	MOD:01518 iTRAQ4plex reporter+balance reagent acylated residue ! iTRAQ4plex reporter+balance reagent acylated residue

2.1486. MOD:01486 iTRAQ4plex-114 reporter+balance reagent acylated N-terminal

Table 1488. Term [MOD:01486]
id	MOD:01486
name	iTRAQ4plex-114 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [OMSSA:167, UniMod:532#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 114" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ114" RELATED UniMod-interim []
synonym	"iTRAQ114nterm" EXACT OMSSA-label []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01711 iTRAQ4plex reporter+balance reagent acylated N-terminal ! iTRAQ4plex reporter+balance reagent acylated N-terminal

2.1487. MOD:01487 iTRAQ4plex-114 reporter+balance reagent N6-acylated lysine

Table 1489. Term [MOD:01487]
id	MOD:01487
name	iTRAQ4plex-114 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [OMSSA:168, UniMod:532#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 114" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ114" RELATED UniMod-interim []
synonym	"iTRAQ114K" EXACT OMSSA-label []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "(12)C 11 (13)C 2 H 24 N 4 (16)O 1 (18)O 1"
xref	MassAvg: "272.20"
xref	MassMono: "272.200882"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1488. MOD:01488 iTRAQ4plex-114 reporter+balance reagent O4'-acylated tyrosine

Table 1490. Term [MOD:01488]
id	MOD:01488
name	iTRAQ4plex-114 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [OMSSA:169, UniMod:532#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 114" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ114" RELATED UniMod-interim []
synonym	"iTRAQ114Y" EXACT OMSSA-label []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "(12)C 14 (13)C 2 H 21 N 3 (16)O 2 (18)O 1"
xref	MassAvg: "307.17"
xref	MassMono: "307.169248"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1489. MOD:01489 iTRAQ4plex-114 reporter+balance reagent N'-acylated histidine

Table 1491. Term [MOD:01489]
id	MOD:01489
name	iTRAQ4plex-114 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "(12)C 11 (13)C 2 H 19 N 5 O 1 (18)O 1"
xref	MassAvg: "281.16"
xref	MassMono: "281.164831"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue

2.1490. MOD:01490 iTRAQ4plex-114 reporter+balance reagent O3-acylated serine

Table 1492. Term [MOD:01490]
id	MOD:01490
name	iTRAQ4plex-114 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "(12)C 8 (13)C 2 H 17 N 3 O 2 (18)O 1"
xref	MassAvg: "231.14"
xref	MassMono: "231.137947"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1491. MOD:01491 iTRAQ4plex-114 reporter+balance reagent O3-acylated threonine

Table 1493. Term [MOD:01491]
id	MOD:01491
name	iTRAQ4plex-114 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ4plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex114" RELATED PSI-MS-label []
xref	DiffAvg: "144.11"
xref	DiffFormula: "(12)C 5 (13)C 2 H 12 N 2 (18)O 1"
xref	DiffMono: "144.105919"
xref	Formula: "(12)C 9 (13)C 2 H 19 N 3 O 2 (18)O 1"
xref	MassAvg: "245.15"
xref	MassMono: "245.153598"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1492. MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue

Table 1494. Term [MOD:01492]
id	MOD:01492
name	iTRAQ4plex-115 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [UniMod:533]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ115" RELATED UniMod-interim []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01430 (18)O isotope tagged reagent ! (18)O isotope tagged reagent
is_a	MOD:01516 modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da. ! modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da.
is_a	MOD:01518 iTRAQ4plex reporter+balance reagent acylated residue ! iTRAQ4plex reporter+balance reagent acylated residue

2.1493. MOD:01493 iTRAQ4plex-115 reporter+balance reagent acylated N-terminal

Table 1495. Term [MOD:01493]
id	MOD:01493
name	iTRAQ4plex-115 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [OMSSA:170, UniMod:533#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ115" RELATED UniMod-interim []
synonym	"iTRAQ115nterm" EXACT OMSSA-label []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01711 iTRAQ4plex reporter+balance reagent acylated N-terminal ! iTRAQ4plex reporter+balance reagent acylated N-terminal

2.1494. MOD:01494 iTRAQ4plex-115 reporter+balance reagent N6-acylated lysine

Table 1496. Term [MOD:01494]
id	MOD:01494
name	iTRAQ4plex-115 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [OMSSA:171, UniMod:533#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ115" RELATED UniMod-interim []
synonym	"iTRAQ115K" EXACT OMSSA-label []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "(12)C 12 (13)C 1 H 24 (14)N 3 (15)N 1 (16)O 1 (18)O 1"
xref	MassAvg: "272.19"
xref	MassMono: "272.194562"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1495. MOD:01495 iTRAQ4plex-115 reporter+balance reagent O4'-acylated tyrosine

Table 1497. Term [MOD:01495]
id	MOD:01495
name	iTRAQ4plex-115 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [OMSSA:172, UniMod:533#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ115" RELATED UniMod-interim []
synonym	"iTRAQ115Y" EXACT OMSSA-label []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "(12)C 15 (13)C 1 H 21 (14)N 2 (15)N 1 (16)O 2 (18)O 1"
xref	MassAvg: "307.16"
xref	MassMono: "307.162928"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1496. MOD:01496 iTRAQ4plex-115 reporter+balance reagent N'-acylated histidine

Table 1498. Term [MOD:01496]
id	MOD:01496
name	iTRAQ4plex-115 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "(12)C 12 (13)C 1 H 19 (14)N 4 (15)N 1 (16)O 1 (18)O 1"
xref	MassAvg: "281.16"
xref	MassMono: "281.158511"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue

2.1497. MOD:01497 iTRAQ4plex-115 reporter+balance reagent O3-acylated serine

Table 1499. Term [MOD:01497]
id	MOD:01497
name	iTRAQ4plex-115 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "(12)C 9 (13)C 1 H 17 N 1 (14)N 1 (15)N 1 (16)O 2 (18)O 1"
xref	MassAvg: "231.13"
xref	MassMono: "231.131628"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1498. MOD:01498 iTRAQ4plex-115 reporter+balance reagent O3-acylated threonine

Table 1500. Term [MOD:01498]
id	MOD:01498
name	iTRAQ4plex-115 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex115" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 6 (13)C 1 H 12 (14)N 1 (15)N 1 (18)O 1"
xref	DiffMono: "144.099599"
xref	Formula: "(12)C 10 (13)C 1 H 19 (14)N 2 (15)N 1 (16)O 2 (18)O 1"
xref	MassAvg: "245.15"
xref	MassMono: "245.147278"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1499. MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue

Table 1501. Term [MOD:01499]
id	MOD:01499
name	iTRAQ4plex-116 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [UniMod:214]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01517 modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da ! modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da
is_a	MOD:01518 iTRAQ4plex reporter+balance reagent acylated residue ! iTRAQ4plex reporter+balance reagent acylated residue

2.1500. MOD:01500 iTRAQ4plex-116 reporter+balance reagent acylated N-terminal

Table 1502. Term [MOD:01500]
id	MOD:01500
name	iTRAQ4plex-116 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [OMSSA:173, UniMod:214#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ116nterm" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01711 iTRAQ4plex reporter+balance reagent acylated N-terminal ! iTRAQ4plex reporter+balance reagent acylated N-terminal

2.1501. MOD:01501 iTRAQ4plex-116 reporter+balance reagent N6-acylated lysine

Table 1503. Term [MOD:01501]
id	MOD:01501
name	iTRAQ4plex-116 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [OMSSA:174, UniMod:214#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ116K" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 10 (13)C 3 H 24 N 2 (14)N 1 (15)N 1 O 1 (16)O 1"
xref	MassAvg: "272.20"
xref	MassMono: "272.197025"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1502. MOD:01502 iTRAQ4plex-116 reporter+balance reagent O4'-acylated tyrosine

Table 1504. Term [MOD:01502]
id	MOD:01502
name	iTRAQ4plex-116 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [OMSSA:175, UniMod:214#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ116Y" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 13 (13)C 3 H 21 N 1 (14)N 1 (15)N 1 O 2 (16)O 1"
xref	MassAvg: "307.17"
xref	MassMono: "307.165391"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1503. MOD:01503 iTRAQ4plex-116 reporter+balance reagent N'-acylated histidine

Table 1505. Term [MOD:01503]
id	MOD:01503
name	iTRAQ4plex-116 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 10 (13)C 3 H 19 N 3 (14)N 1 (15)N 1 (16)O 2"
xref	MassAvg: "281.16"
xref	MassMono: "281.160974"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue

2.1504. MOD:01504 iTRAQ4plex-116 reporter+balance reagent O3-acylated serine

Table 1506. Term [MOD:01504]
id	MOD:01504
name	iTRAQ4plex-116 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 7 (13)C 3 H 17 (14)N 2 (15)N 1 (16)O 3"
xref	MassAvg: "231.13"
xref	MassMono: "231.134091"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1505. MOD:01505 iTRAQ4plex-116 reporter+balance reagent O3-acylated threonine

Table 1507. Term [MOD:01505]
id	MOD:01505
name	iTRAQ4plex-116 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 8 (13)C 3 H 19 (14)N 2 (15)N 1 (16)O 3"
xref	MassAvg: "245.15"
xref	MassMono: "245.149741"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1506. MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue

Table 1508. Term [MOD:01506]
id	MOD:01506
name	iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [UniMod:214, UniMod:889]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"mTRAQ heavy" RELATED UniMod-description []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01517 modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da ! modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da
is_a	MOD:01518 iTRAQ4plex reporter+balance reagent acylated residue ! iTRAQ4plex reporter+balance reagent acylated residue
is_a	MOD:01863 mTRAQ reporter+balance reagent acylated residue ! mTRAQ reporter+balance reagent acylated residue

2.1507. MOD:01507 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated N-terminal

Table 1509. Term [MOD:01507]
id	MOD:01507
name	iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [OMSSA:176, OMSSA:211, UniMod:214#N-term, UniMod:889N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ117nterm" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"mTRAQ heavy" RELATED UniMod-description []
synonym	"mTRAQ heavy on nterm" EXACT OMSSA-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01711 iTRAQ4plex reporter+balance reagent acylated N-terminal ! iTRAQ4plex reporter+balance reagent acylated N-terminal

2.1508. MOD:01508 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent N6-acylated lysine

Table 1510. Term [MOD:01508]
id	MOD:01508
name	iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [OMSSA:177, OMSSA:212, UniMod:214#K, UniMod:889#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ117K" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"mTRAQ heavy" RELATED UniMod-description []
synonym	"mTRAQ heavy on K" EXACT OMSSA-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 10 (13)C 3 H 24 N 2 (14)N 1 (15)N 1 O 1 (16)O 1"
xref	MassAvg: "272.20"
xref	MassMono: "272.197025"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1509. MOD:01509 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent O4'-acylated tyrosine

Table 1511. Term [MOD:01509]
id	MOD:01509
name	iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [OMSSA:178, OMSSA:213, UniMod:214#Y, UniMod:889#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"iTRAQ" RELATED UniMod-interim []
synonym	"iTRAQ117Y" EXACT OMSSA-label []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
synonym	"mTRAQ heavy" RELATED UniMod-description []
synonym	"mTRAQ heavy on Y" EXACT OMSSA-label []
synonym	"Representative mass and accurate mass for 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 13 (13)C 3 H 21 N 1 (14)N 1 (15)N 1 O 2 (16)O 1"
xref	MassAvg: "307.17"
xref	MassMono: "307.165391"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1510. MOD:01510 iTRAQ4plex-117 reporter+balance reagent N'-acylated histidine

Table 1512. Term [MOD:01510]
id	MOD:01510
name	iTRAQ4plex-117 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 10 (13)C 3 H 19 (14)N 4 (15)N 1 (16)O 2"
xref	MassAvg: "281.16"
xref	MassMono: "281.160974"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue

2.1511. MOD:01511 iTRAQ4plex-117 reporter+balance reagent O3-acylated serine

Table 1513. Term [MOD:01511]
id	MOD:01511
name	iTRAQ4plex-117 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 7 (13)C 3 H 17 (14)N 2 (15)N 1 (16)O 3"
xref	MassAvg: "231.13"
xref	MassMono: "231.134091"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1512. MOD:01512 iTRAQ4plex-117 reporter+balance reagent O3-acylated threonine

Table 1514. Term [MOD:01512]
id	MOD:01512
name	iTRAQ4plex-117 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"iTRAQ4plex" RELATED PSI-MS-label []
xref	DiffAvg: "144.10"
xref	DiffFormula: "(12)C 4 (13)C 3 H 12 (14)N 1 (15)N 1 (16)O 1"
xref	DiffMono: "144.102062"
xref	Formula: "(12)C 8 (13)C 3 H 19 (14)N 2 (15)N 1 (16)O 3"
xref	MassAvg: "245.15"
xref	MassMono: "245.149741"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue
is_a	MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue ! iTRAQ4plex reporter+balance reagent O-acylated residue

2.1513. MOD:01513 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.1 Da

Table 1515. Term [MOD:01513]
id	MOD:01513
name	modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.1 Da
def	"Modifications that have monoisotopic mass differences from their respective origins that are nominally equal (sometimes called isobaric) at a resolution below 0.1 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00538 protein modification categorized by isobaric sets ! protein modification categorized by isobaric sets

2.1514. MOD:01514 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da

Table 1516. Term [MOD:01514]
id	MOD:01514
name	modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da
def	"Modifications that have monoisotopic mass differences from their respective origins that are nominally equal (sometimes called isobaric) at a resolution below 0.01 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01513 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.1 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.1 Da

2.1515. MOD:01515 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da

Table 1517. Term [MOD:01515]
id	MOD:01515
name	modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da
def	"Modifications that have monoisotopic mass differences from their respective origins that are nominally equal (sometimes called isobaric) at a resolution below 0.000001 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01514 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da

2.1516. MOD:01516 modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da.

Table 1518. Term [MOD:01516]
id	MOD:01516
name	modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da.
def	"Modifications that have monoisotopic mass differences from their respective origins of 144.099-144.106 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01514 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da

2.1517. MOD:01517 modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da

Table 1519. Term [MOD:01517]
id	MOD:01517
name	modifications with monoisotopic mass differences that are nominally equal at 144.102062 Da
def	"Modifications that have monoisotopic mass differences from their respective origins of 144.102062 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01515 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da
is_a	MOD:01516 modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da. ! modifications with monoisotopic mass diferences that are nominally equal at 144.099-144.106 Da.

2.1518. MOD:01518 iTRAQ4plex reporter+balance reagent acylated residue

Table 1520. Term [MOD:01518]
id	MOD:01518
name	iTRAQ4plex reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with one of the Applied Biosystems iTRAQ4plex reagent reporter+balance groups." [UniMod:214]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01705 isotope tagged reagent acylated residue ! isotope tagged reagent acylated residue

2.1519. MOD:01519 reporter fragment

Table 1521. Term [MOD:01519]
id	MOD:01519
name	reporter fragment
def	"A distinct molecular entity produced from a protein or a protein modification as the result of a fragmentation process." [PubMed:18688235]
comment	The reporter fragment is either itself a modification consisting of atoms derived from the original amino acid residues, or its detection can be taken as evidence that particular modified residues had been present.
subset	PSI-MOD-slim
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1520. MOD:01520 modification reporter fragment

Table 1522. Term [MOD:01520]
id	MOD:01520
name	modification reporter fragment
def	"A distinct molecular entity produced as the result of a fragmentation process performed on a particular modified residue." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01519 reporter fragment ! reporter fragment

2.1521. MOD:01521 iTRAQ4plex reporter fragment

Table 1523. Term [MOD:01521]
id	MOD:01521
name	iTRAQ4plex reporter fragment
def	"A protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment

2.1522. MOD:01522 iTRAQ4plex-114 reporter fragment

Table 1524. Term [MOD:01522]
id	MOD:01522
name	iTRAQ4plex-114 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 114 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 5 (13)C 1 H 13 (14)N 2"
xref	MassAvg: "114.11"
xref	MassMono: "114.110680"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01521 iTRAQ4plex reporter fragment ! iTRAQ4plex reporter fragment
relationship	derives_from MOD:01485 iTRAQ4plex-114 reporter+balance reagent acylated residue ! iTRAQ4plex-114 reporter+balance reagent acylated residue

2.1523. MOD:01523 iTRAQ4plex-115 reporter fragment

Table 1525. Term [MOD:01523]
id	MOD:01523
name	iTRAQ4plex-115 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 115 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 5 (13)C 1 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "115.11"
xref	MassMono: "115.107715"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01521 iTRAQ4plex reporter fragment ! iTRAQ4plex reporter fragment
relationship	derives_from MOD:01492 iTRAQ4plex-115 reporter+balance reagent acylated residue ! iTRAQ4plex-115 reporter+balance reagent acylated residue

2.1524. MOD:01524 iTRAQ4plex-116 reporter fragment

Table 1526. Term [MOD:01524]
id	MOD:01524
name	iTRAQ4plex-116 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 116 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 4 (13)C 2 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "116.11"
xref	MassMono: "116.111069"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01521 iTRAQ4plex reporter fragment ! iTRAQ4plex reporter fragment
relationship	derives_from MOD:01499 iTRAQ4plex-116 reporter+balance reagent acylated residue ! iTRAQ4plex-116 reporter+balance reagent acylated residue

2.1525. MOD:01525 iTRAQ4plex-117, mTRAQ heavy, reporter fragment

Table 1527. Term [MOD:01525]
id	MOD:01525
name	iTRAQ4plex-117, mTRAQ heavy, reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 117 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 3 (13)C 3 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "117.11"
xref	MassMono: "117.114424"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01521 iTRAQ4plex reporter fragment ! iTRAQ4plex reporter fragment
is_a	MOD:01870 mTRAQ reporter fragment ! mTRAQ reporter fragment
relationship	derives_from MOD:01506 iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue ! iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue

2.1526. MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue

Table 1528. Term [MOD:01526]
id	MOD:01526
name	iTRAQ8plex reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with one of the Applied Biosystems iTRAQ8plex reagent reporter+balance groups." [UniMod:730]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01705 isotope tagged reagent acylated residue ! isotope tagged reagent acylated residue

2.1527. MOD:01527 residue reporter fragment

Table 1529. Term [MOD:01527]
id	MOD:01527
name	residue reporter fragment
def	"A distinct molecular entity produced from a particular amino acid residue as the result of a fragmentation process." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01519 reporter fragment ! reporter fragment

2.1528. MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue

Table 1530. Term [MOD:01528]
id	MOD:01528
name	iTRAQ8plex-113 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [UniMod:730]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01591 modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da

2.1529. MOD:01529 iTRAQ8plex-113 reporter+balance reagent acylated N-terminal

Table 1531. Term [MOD:01529]
id	MOD:01529
name	iTRAQ8plex-113 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [UniMod:730#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1530. MOD:01530 iTRAQ8plex-113 reporter+balance reagent N6-acylated lysine

Table 1532. Term [MOD:01530]
id	MOD:01530
name	iTRAQ8plex-113 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [UniMod:730#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 36 (14)N 5 (15)N 1 (16)O 4"
xref	MassAvg: "432.30"
xref	MassMono: "432.300322"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1531. MOD:01531 iTRAQ8plex-113 reporter+balance reagent O4'-acylated tyrosine

Table 1533. Term [MOD:01531]
id	MOD:01531
name	iTRAQ8plex-113 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [UniMod:730#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 16 (13)C 7 H 33 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "467.27"
xref	MassMono: "467.268688"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1532. MOD:01532 iTRAQ8plex-113 reporter+balance reagent N'-acylated histidine

Table 1534. Term [MOD:01532]
id	MOD:01532
name	iTRAQ8plex-113 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 31 (14)N 6 (15)N 1 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.264271"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1533. MOD:01533 iTRAQ8plex-113 reporter+balance reagent O3-acylated serine

Table 1535. Term [MOD:01533]
id	MOD:01533
name	iTRAQ8plex-113 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 10 (13)C 7 H 29 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "391.24"
xref	MassMono: "391.237388"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1534. MOD:01534 iTRAQ8plex-113 reporter+balance reagent O3-acylated threonine

Table 1536. Term [MOD:01534]
id	MOD:01534
name	iTRAQ8plex-113 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 11 (13)C 7 H 31 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.253038"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1535. MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue

Table 1537. Term [MOD:01535]
id	MOD:01535
name	iTRAQ8plex-114 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [UniMod:730]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01591 modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da

2.1536. MOD:01536 iTRAQ8plex-114 reporter+balance reagent acylated N-terminal

Table 1538. Term [MOD:01536]
id	MOD:01536
name	iTRAQ8plex-114 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [UniMod:730#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1537. MOD:01537 iTRAQ8plex-114 reporter+balance reagent N6-acylated lysine

Table 1539. Term [MOD:01537]
id	MOD:01537
name	iTRAQ8plex-114 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [UniMod:730#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 36 (14)N 5 (15)N 1 (16)O 4"
xref	MassAvg: "432.30"
xref	MassMono: "432.300322"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1538. MOD:01538 iTRAQ8plex-114 reporter+balance reagent O4'-acylated tyrosine

Table 1540. Term [MOD:01538]
id	MOD:01538
name	iTRAQ8plex-114 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [UniMod:730#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 16 (13)C 7 H 33 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "467.27"
xref	MassMono: "467.268688"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1539. MOD:01539 iTRAQ8plex-114 reporter+balance reagent N'-acylated histidine

Table 1541. Term [MOD:01539]
id	MOD:01539
name	iTRAQ8plex-114 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 31 (14)N 6 (15)N 1 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.264271"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1540. MOD:01540 iTRAQ8plex-114 reporter+balance reagent O3-acylated serine

Table 1542. Term [MOD:01540]
id	MOD:01540
name	iTRAQ8plex-114 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 10 (13)C 7 H 29 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "391.24"
xref	MassMono: "391.237388"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1541. MOD:01541 iTRAQ8plex-114 reporter+balance reagent O3-acylated threonine

Table 1543. Term [MOD:01541]
id	MOD:01541
name	iTRAQ8plex-114 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 11 (13)C 7 H 31 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.253038"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1542. MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue

Table 1544. Term [MOD:01542]
id	MOD:01542
name	iTRAQ8plex-115 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [UniMod:731]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01584 modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da

2.1543. MOD:01543 iTRAQ8plex-115 reporter+balance reagent acylated N-terminal

Table 1545. Term [MOD:01543]
id	MOD:01543
name	iTRAQ8plex-115 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [UniMod:731#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1544. MOD:01544 iTRAQ8plex-115 reporter+balance reagent N6-acylated lysine

Table 1546. Term [MOD:01544]
id	MOD:01544
name	iTRAQ8plex-115 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [UniMod:731#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 36 (14)N 4 (15)N 2 (16)O 4"
xref	MassAvg: "432.29"
xref	MassMono: "432.294002"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1545. MOD:01545 iTRAQ8plex-115 reporter+balance reagent O4'-acylated tyrosine

Table 1547. Term [MOD:01545]
id	MOD:01545
name	iTRAQ8plex-115 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [UniMod:731#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 17 (13)C 6 H 33 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "467.26"
xref	MassMono: "467.262368"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1546. MOD:01546 iTRAQ8plex-115 reporter+balance reagent N'-derivatized histidine

Table 1548. Term [MOD:01546]
id	MOD:01546
name	iTRAQ8plex-115 reporter+balance reagent N'-derivatized histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 31 (14)N 5 (15)N 2 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.257951"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1547. MOD:01547 iTRAQ8plex-115 reporter+balance reagent O3-acylated serine

Table 1549. Term [MOD:01547]
id	MOD:01547
name	iTRAQ8plex-115 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 11 (13)C 6 H 29 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "391.23"
xref	MassMono: "391.231068"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1548. MOD:01548 iTRAQ8plex-115 reporter+balance reagent O3-acylated threonine

Table 1550. Term [MOD:01548]
id	MOD:01548
name	iTRAQ8plex-115 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-115 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 12 (13)C 6 H 31 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.246718"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1549. MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue

Table 1551. Term [MOD:01549]
id	MOD:01549
name	iTRAQ8plex-116 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [UniMod:730]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01591 modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da

2.1550. MOD:01550 iTRAQ8plex-116 reporter+balance reagent acylated N-terminal

Table 1552. Term [MOD:01550]
id	MOD:01550
name	iTRAQ8plex-116 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [UniMod:730#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1551. MOD:01551 iTRAQ8plex-116 reporter+balance reagent N6-acylated lysine

Table 1553. Term [MOD:01551]
id	MOD:01551
name	iTRAQ8plex-116 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [UniMod:730#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 36 (14)N 5 (15)N 1 (16)O 4"
xref	MassAvg: "432.30"
xref	MassMono: "432.300322"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1552. MOD:01552 iTRAQ8plex-116 reporter+balance reagent O4'-acylated tyrosine

Table 1554. Term [MOD:01552]
id	MOD:01552
name	iTRAQ8plex-116 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [UniMod:730#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 16 (13)C 7 H 33 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "467.27"
xref	MassMono: "467.268688"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1553. MOD:01553 iTRAQ8plex-116 reporter+balance reagent N'-acylated histidine

Table 1555. Term [MOD:01553]
id	MOD:01553
name	iTRAQ8plex-116 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 31 (14)N 6 (15)N 1 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.264271"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1554. MOD:01554 iTRAQ8plex-116 reporter+balance reagent O3-acylated serine

Table 1556. Term [MOD:01554]
id	MOD:01554
name	iTRAQ8plex-116 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 10 (13)C 7 H 29 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "391.24"
xref	MassMono: "391.237388"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1555. MOD:01555 iTRAQ8plex-116 reporter+balance reagent O3-acylated threonine

Table 1557. Term [MOD:01555]
id	MOD:01555
name	iTRAQ8plex-116 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-116 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 11 (13)C 7 H 31 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.253038"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1556. MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue

Table 1558. Term [MOD:01556]
id	MOD:01556
name	iTRAQ8plex-117 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [UniMod:730]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01591 modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da

2.1557. MOD:01557 iTRAQ8plex-117 reporter+balance reagent acylated N-terminal

Table 1559. Term [MOD:01557]
id	MOD:01557
name	iTRAQ8plex-117 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [UniMod:730#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1558. MOD:01558 iTRAQ8plex-117 reporter+balance reagent N6-acylated lysine

Table 1560. Term [MOD:01558]
id	MOD:01558
name	iTRAQ8plex-117 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [UniMod:730#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 36 (14)N 5 (15)N 1 (16)O 4"
xref	MassAvg: "432.30"
xref	MassMono: "432.300322"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1559. MOD:01559 iTRAQ8plex-117 reporter+balance reagent O4'-acylated tyrosine

Table 1561. Term [MOD:01559]
id	MOD:01559
name	iTRAQ8plex-117 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [UniMod:730#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex" RELATED UniMod-interim []
synonym	"iTRAQ8plex:13C(7)15N(1)" RELATED UniMod-alternate []
synonym	"Representative mass and accurate mass for 113, 114, 116 & 117" RELATED UniMod-description []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 16 (13)C 7 H 33 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "467.27"
xref	MassMono: "467.268688"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1560. MOD:01560 iTRAQ8plex-117 reporter+balance reagent N'-acylated histidine

Table 1562. Term [MOD:01560]
id	MOD:01560
name	iTRAQ8plex-117 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 13 (13)C 7 H 31 (14)N 6 (15)N 1 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.264271"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1561. MOD:01561 iTRAQ8plex-117 reporter+balance reagent O3-acylated serine

Table 1563. Term [MOD:01561]
id	MOD:01561
name	iTRAQ8plex-117 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 10 (13)C 7 H 29 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "391.24"
xref	MassMono: "391.237388"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1562. MOD:01562 iTRAQ8plex-117 reporter+balance reagent O3-acylated threonine

Table 1564. Term [MOD:01562]
id	MOD:01562
name	iTRAQ8plex-117 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-117 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.21"
xref	DiffFormula: "(12)C 7 (13)C 7 H 24 (14)N 3 (15)N 1 (16)O 3"
xref	DiffMono: "304.205359"
xref	Formula: "(12)C 11 (13)C 7 H 31 (14)N 4 (15)N 1 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.253038"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1563. MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue

Table 1565. Term [MOD:01563]
id	MOD:01563
name	iTRAQ8plex-118 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [UniMod:731]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01584 modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da

2.1564. MOD:01564 iTRAQ8plex-118 reporter+balance reagent acylated N-terminal

Table 1566. Term [MOD:01564]
id	MOD:01564
name	iTRAQ8plex-118 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [UniMod:731#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1565. MOD:01565 iTRAQ8plex-118 reporter+balance reagent N6-acylated lysine

Table 1567. Term [MOD:01565]
id	MOD:01565
name	iTRAQ8plex-118 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [UniMod:731#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 36 (14)N 4 (15)N 2 (16)O 4"
xref	MassAvg: "432.29"
xref	MassMono: "432.294002"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1566. MOD:01566 iTRAQ8plex-118 reporter+balance reagent O4'-acylated tyrosine

Table 1568. Term [MOD:01566]
id	MOD:01566
name	iTRAQ8plex-118 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [UniMod:731#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 17 (13)C 6 H 33 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "467.26"
xref	MassMono: "467.262368"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1567. MOD:01567 iTRAQ8plex-118 reporter+balance reagent N'-acylated histidine

Table 1569. Term [MOD:01567]
id	MOD:01567
name	iTRAQ8plex-118 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 31 (14)N 5 (15)N 2 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.257951"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1568. MOD:01568 iTRAQ8plex-118 reporter+balance reagent O3-acylated serine

Table 1570. Term [MOD:01568]
id	MOD:01568
name	iTRAQ8plex-118 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 11 (13)C 6 H 29 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "391.23"
xref	MassMono: "391.231068"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1569. MOD:01569 iTRAQ8plex-118 reporter+balance reagent O3-acylated threonine

Table 1571. Term [MOD:01569]
id	MOD:01569
name	iTRAQ8plex-118 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-118 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 12 (13)C 6 H 31 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.246718"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1570. MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue

Table 1572. Term [MOD:01570]
id	MOD:01570
name	iTRAQ8plex-119 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [UniMod:731]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01584 modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da

2.1571. MOD:01571 iTRAQ8plex-119 reporter+balance reagent acylated N-terminal

Table 1573. Term [MOD:01571]
id	MOD:01571
name	iTRAQ8plex-119 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [UniMod:731#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1572. MOD:01572 iTRAQ8plex-119 reporter+balance reagent N6-acylated lysine

Table 1574. Term [MOD:01572]
id	MOD:01572
name	iTRAQ8plex-119 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [UniMod:731#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 36 (14)N 4 (15)N 2 (16)O 4"
xref	MassAvg: "432.29"
xref	MassMono: "432.294002"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1573. MOD:01573 iTRAQ8plex-119 reporter+balance reagent O4'-acylated tyrosine

Table 1575. Term [MOD:01573]
id	MOD:01573
name	iTRAQ8plex-119 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [UniMod:731#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 17 (13)C 6 H 33 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "467.26"
xref	MassMono: "467.262368"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1574. MOD:01574 iTRAQ8plex-119 reporter+balance reagent N'-acylated histidine

Table 1576. Term [MOD:01574]
id	MOD:01574
name	iTRAQ8plex-119 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 31 (14)N 5 (15)N 2 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.257951"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1575. MOD:01575 iTRAQ8plex-119 reporter+balance reagent O3-acylated serine

Table 1577. Term [MOD:01575]
id	MOD:01575
name	iTRAQ8plex-119 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 11 (13)C 6 H 29 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "391.23"
xref	MassMono: "391.231068"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1576. MOD:01576 iTRAQ8plex-119 reporter+balance reagent O3-acylated threonine

Table 1578. Term [MOD:01576]
id	MOD:01576
name	iTRAQ8plex-119 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-119 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 12 (13)C 6 H 31 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.246718"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1577. MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue

Table 1579. Term [MOD:01577]
id	MOD:01577
name	iTRAQ8plex-121 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [UniMod:731]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01526 iTRAQ8plex reporter+balance reagent acylated residue ! iTRAQ8plex reporter+balance reagent acylated residue
is_a	MOD:01584 modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da

2.1578. MOD:01578 iTRAQ8plex-121 reporter+balance reagent acylated N-terminal

Table 1580. Term [MOD:01578]
id	MOD:01578
name	iTRAQ8plex-121 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [UniMod:731#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal ! iTRAQ8plex reporter+balance reagent acylated N-terminal

2.1579. MOD:01579 iTRAQ8plex-121 reporter+balance reagent N6-acylated lysine

Table 1581. Term [MOD:01579]
id	MOD:01579
name	iTRAQ8plex-121 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [UniMod:731#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 36 (14)N 4 (15)N 2 (16)O 4"
xref	MassAvg: "432.29"
xref	MassMono: "432.294002"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1580. MOD:01580 iTRAQ8plex-121 reporter+balance reagent O4'-acylated tyrosine

Table 1582. Term [MOD:01580]
id	MOD:01580
name	iTRAQ8plex-121 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [UniMod:731#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Accurate mass for 115, 118, 119 & 121" RELATED UniMod-description []
synonym	"Applied Biosystems iTRAQ™ multiplexed quantitation chemistry" RELATED UniMod-alternate []
synonym	"iTRAQ8plex:13C(6)15N(2)" RELATED UniMod-interim []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 17 (13)C 6 H 33 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "467.26"
xref	MassMono: "467.262368"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1581. MOD:01581 iTRAQ8plex-121 reporter+balance reagent N'-acylated histidine

Table 1583. Term [MOD:01581]
id	MOD:01581
name	iTRAQ8plex-121 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 14 (13)C 6 H 31 (14)N 5 (15)N 2 (16)O 4"
xref	MassAvg: "441.26"
xref	MassMono: "441.257951"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1582. MOD:01582 iTRAQ8plex-121 reporter+balance reagent O3-acylated serine

Table 1584. Term [MOD:01582]
id	MOD:01582
name	iTRAQ8plex-121 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 11 (13)C 6 H 29 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "391.23"
xref	MassMono: "391.231068"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1583. MOD:01583 iTRAQ8plex-121 reporter+balance reagent O3-acylated threonine

Table 1585. Term [MOD:01583]
id	MOD:01583
name	iTRAQ8plex-121 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ8plex-121 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.20"
xref	DiffFormula: "(12)C 8 (13)C 6 H 24 (14)N 2 (15)N 2 (16)O 3"
xref	DiffMono: "304.199039"
xref	Formula: "(12)C 12 (13)C 6 H 31 (14)N 3 (15)N 2 (16)O 5"
xref	MassAvg: "405.25"
xref	MassMono: "405.246718"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue
is_a	MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue ! iTRAQ8plex reporter+balance reagent O-acylated residue

2.1584. MOD:01584 modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da

Table 1586. Term [MOD:01584]
id	MOD:01584
name	modifications with monoisotopic mass differences that are nominally equal at 304.199039 Da
def	"Modifications that have monoisotopic mass differences from their respective origins of 304.199039 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01515 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da
is_a	MOD:01592 modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da

2.1585. MOD:01585 O-glycyl-L-serine

Table 1587. Term [MOD:01585]
id	MOD:01585
name	O-glycyl-L-serine
def	"A protein modification that effectively crosslinks an L-serine residue and a glycine residue by an ester bond to form O-glycyl-L-serine." [PubMed:17502423, RESID:AA0495]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-[(aminoacetyl)oxy]propanoic acid" EXACT RESID-systematic []
synonym	"O-(glycyl)-L-serine" EXACT RESID-name []
synonym	"O3-(aminoacetyl)serine" EXACT RESID-alternate []
synonym	"serine glycinate ester" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 7 N 2 O 3"
xref	MassAvg: "143.12"
xref	MassMono: "143.045667"
xref	Origin: "G, S"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.1586. MOD:01586 O-glycyl-L-threonine

Table 1588. Term [MOD:01586]
id	MOD:01586
name	O-glycyl-L-threonine
def	"A protein modification that effectively crosslinks an L-threonine residue and a glycine residue by an ester bond to form O-glycyl-L-threonine." [PubMed:17502423, RESID:AA0496]
comment	Cross-link 2.
synonym	"(2S,3R)-2-amino-3-[(aminoacetyl)oxy]butanoic acid" EXACT RESID-systematic []
synonym	"O-(glycyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(2-aminoacetyl)threonine" EXACT RESID-alternate []
synonym	"threonine glycinate ester" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 9 N 2 O 3"
xref	MassAvg: "157.15"
xref	MassMono: "157.061317"
xref	Origin: "G, T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.1587. MOD:01587 O-(2-aminoethylphosphoryl)-L-serine

Table 1589. Term [MOD:01587]
id	MOD:01587
name	O-(2-aminoethylphosphoryl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(2-aminoethylphosphoryl)-L-serine." [PubMed:15249686, PubMed:16825186, PubMed:16949362, RESID:AA0497]
synonym	"(2S)-2-amino-3-([(2-aminoethoxy)(hydroxy)phosphoryl]oxy)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES O-(2-aminoethylphosphoryl)serine" EXACT UniProt-feature []
synonym	"O-(2-aminoethylphosphoryl)-L-serine" EXACT RESID-name []
synonym	"O3-(2-aminoethylphosphoryl)-L-serine" EXACT RESID-alternate []
synonym	"O3-(phosphoethanolamine)-L-serine" EXACT RESID-alternate []
synonym	"serine ethanolamine phosphate" EXACT RESID-alternate []
synonym	"serine ethanolamine phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "123.05"
xref	DiffFormula: "C 2 H 6 N 1 O 3 P 1"
xref	DiffMono: "123.008530"
xref	Formula: "C 5 H 11 N 2 O 5 P 1"
xref	MassAvg: "210.13"
xref	MassMono: "210.040558"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1588. MOD:01588 O-cholinephosphoryl-L-serine

Table 1590. Term [MOD:01588]
id	MOD:01588
name	O-cholinephosphoryl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-cholinephosphoryl-L-serine." [PubMed:15249686, PubMed:16825186, PubMed:16949362, RESID:AA0498]
synonym	"2-[([(2S)-2-amino-2-carboxyethoxy][hydroxy]phosphoryl)oxy]-N,N,N-trimethylethanaminium" EXACT RESID-systematic []
synonym	"2-[([(2S)-2-azanyl-2-carboxyethoxy][hydroxy]phosphoryl)oxy]-N,N,N-trimethylethanazanium" EXACT RESID-alternate []
synonym	"MOD_RES O-(2-cholinephosphoryl)serine" EXACT UniProt-feature []
synonym	"O-cholinephosphoryl-L-serine" EXACT RESID-name []
synonym	"O3-[(2-[trimethylammonio]ethyl)phosphoryl]-L-serine" EXACT RESID-alternate []
synonym	"O3-phosphocholine-L-serine" EXACT RESID-alternate []
synonym	"serine choline phosphate" EXACT RESID-alternate []
synonym	"serine choline phosphodiester" EXACT RESID-alternate []
xref	DiffAvg: "166.14"
xref	DiffFormula: "C 5 H 13 N 1 O 3 P 1"
xref	DiffMono: "166.062756"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 18 N 2 O 5 P 1"
xref	MassAvg: "253.21"
xref	MassMono: "253.094785"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1589. MOD:01589 O-(2,4-diacetamido-2,4-dideoxyglucosyl)-L-serine

Table 1591. Term [MOD:01589]
id	MOD:01589
name	O-(2,4-diacetamido-2,4-dideoxyglucosyl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(2,4-diacetamido-2,4-dideoxyglucosyl)-L-serine." [PubMed:15249686, PubMed:16949362, RESID:AA0499]
synonym	"(2S)-2-amino-3-[(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)oxy]propanoic acid" EXACT RESID-systematic []
synonym	"DADDGlc" EXACT RESID-alternate []
synonym	"O-(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O-(2,4-diacetamido-2,4-dideoxy-D-glucosyl)-L-serine" EXACT RESID-name []
synonym	"O-[2,4-bis(acetylamino)]glucosyl-L-serine" EXACT RESID-alternate []
synonym	"O-seryl-beta-2,4-bis(acetylamino)glucoside" EXACT RESID-alternate []
synonym	"O3-(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)-L-serine" EXACT RESID-alternate []
xref	DiffAvg: "244.25"
xref	DiffFormula: "C 10 H 16 N 2 O 5"
xref	DiffMono: "244.105922"
xref	Formula: "C 13 H 21 N 3 O 7"
xref	MassAvg: "331.33"
xref	MassMono: "331.137950"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.1590. MOD:01590 3'-farnesyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan

Table 1592. Term [MOD:01590]
id	MOD:01590
name	3'-farnesyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 3'-farnesyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan." [ChEBI:52950, PubMed:18323630, RESID:AA0500]
synonym	"(2S,3aR,8aS)-3a-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid" EXACT RESID-systematic []
synonym	"3'-farnesyl-2',3'-dihydro-2',N2-cyclo-L-tryptophan" EXACT RESID-name []
synonym	"LIPID 3'-farnesyl-2',N2-cyclotryptophan" EXACT UniProt-feature []
xref	DiffAvg: "204.36"
xref	DiffFormula: "C 15 H 24 N 0 O 0"
xref	DiffMono: "204.187801"
xref	Formula: "C 26 H 34 N 2 O 1"
xref	MassAvg: "390.57"
xref	MassMono: "390.267114"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00437 farnesylated residue ! farnesylated residue
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:01115 isoprenylated tryptophan ! isoprenylated tryptophan

2.1591. MOD:01591 modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da

Table 1593. Term [MOD:01591]
id	MOD:01591
name	modifications with monoisotopic mass differences that are nominally equal at 304.205359 Da
def	"Modifications that have monoisotopic mass differences from their respective origins of 304.205359 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01515 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da
is_a	MOD:01592 modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da ! modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da

2.1592. MOD:01592 modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da

Table 1594. Term [MOD:01592]
id	MOD:01592
name	modifications with monoisotopic mass differences that are nominally equal at 304.199-304.206 Da
def	"Modifications that have monoisotopic mass differences from their respective origins of 304.199-304.206 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01514 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.01 Da

2.1593. MOD:01593 iTRAQ8plex reporter fragment

Table 1595. Term [MOD:01593]
id	MOD:01593
name	iTRAQ8plex reporter fragment
def	"A protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment

2.1594. MOD:01594 iTRAQ8plex-113 reporter fragment

Table 1596. Term [MOD:01594]
id	MOD:01594
name	iTRAQ8plex-113 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-113 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 6 H 13 (14)N 2"
xref	MassAvg: "113.11"
xref	MassMono: "113.107325"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01528 iTRAQ8plex-113 reporter+balance reagent acylated residue ! iTRAQ8plex-113 reporter+balance reagent acylated residue

2.1595. MOD:01595 iTRAQ8plex-114 reporter fragment

Table 1597. Term [MOD:01595]
id	MOD:01595
name	iTRAQ8plex-114 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-114 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 5 (13)C 1 H 13 (14)N 2"
xref	MassAvg: "114.11"
xref	MassMono: "114.110680"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01535 iTRAQ8plex-114 reporter+balance reagent acylated residue ! iTRAQ8plex-114 reporter+balance reagent acylated residue

2.1596. MOD:01596 iTRAQ8plex-115 reporter fragment

Table 1598. Term [MOD:01596]
id	MOD:01596
name	iTRAQ8plex-115 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-115 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 5 (13)C 1 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "115.11"
xref	MassMono: "115.107715"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01542 iTRAQ8plex-115 reporter+balance reagent acylated residue ! iTRAQ8plex-115 reporter+balance reagent acylated residue

2.1597. MOD:01597 iTRAQ8plex-116 reporter fragment

Table 1599. Term [MOD:01597]
id	MOD:01597
name	iTRAQ8plex-116 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-116 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 4 (13)C 2 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "116.11"
xref	MassMono: "116.111069"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01549 iTRAQ8plex-116 reporter+balance reagent acylated residue ! iTRAQ8plex-116 reporter+balance reagent acylated residue

2.1598. MOD:01598 iTRAQ8plex-117 reporter fragment

Table 1600. Term [MOD:01598]
id	MOD:01598
name	iTRAQ8plex-117 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-117 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 3 (13)C 3 H 13 (14)N 1 (15)N 1"
xref	MassAvg: "117.11"
xref	MassMono: "117.114424"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01556 iTRAQ8plex-117 reporter+balance reagent acylated residue ! iTRAQ8plex-117 reporter+balance reagent acylated residue

2.1599. MOD:01599 iTRAQ8plex-118 reporter fragment

Table 1601. Term [MOD:01599]
id	MOD:01599
name	iTRAQ8plex-118 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-118 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 3 (13)C 3 H 13 (15)N 2"
xref	MassAvg: "118.11"
xref	MassMono: "118.111459"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01563 iTRAQ8plex-118 reporter+balance reagent acylated residue ! iTRAQ8plex-118 reporter+balance reagent acylated residue

2.1600. MOD:01600 iTRAQ8plex-119 reporter fragment

Table 1602. Term [MOD:01600]
id	MOD:01600
name	iTRAQ8plex-119 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-119 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 2 (13)C 4 H 13 (15)N 2"
xref	MassAvg: "119.11"
xref	MassMono: "119.114814"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01570 iTRAQ8plex-119 reporter+balance reagent acylated residue ! iTRAQ8plex-119 reporter+balance reagent acylated residue

2.1601. MOD:01601 iTRAQ8plex-121 reporter fragment

Table 1603. Term [MOD:01601]
id	MOD:01601
name	iTRAQ8plex-121 reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ8plex-121 reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(13)C 6 H 13 (15)N 2"
xref	MassAvg: "121.12"
xref	MassMono: "121.121524"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01593 iTRAQ8plex reporter fragment ! iTRAQ8plex reporter fragment
relationship	derives_from MOD:01577 iTRAQ8plex-121 reporter+balance reagent acylated residue ! iTRAQ8plex-121 reporter+balance reagent acylated residue

2.1602. MOD:01602 S-(L-lysyl)-L-methionine sulfilimine

Table 1604. Term [MOD:01602]
id	MOD:01602
name	S-(L-lysyl)-L-methionine sulfilimine
def	"A protein modification that effectively converts an L-lysine residue, and an L-methionine residue to S-(L-lysyl)-L-methionine sulfilimine." [PubMed:12011424, PubMed:15951440, PubMed:19729652, RESID:AA0501]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(E)-[(3S)-3-amino-3-carboxypropyl](methyl)-lambda(4)-sulfanylidene]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"(E)-N6-([(3S)-3-amino-3-carboxypropyl](methyl)-lambda(4)-sulfanylidene)-L-lysine" EXACT RESID-alternate []
synonym	"S-(L-lysyl)-L-methionine sulfilimine" EXACT RESID-name []
synonym	"S-lysyl-methionine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 11 H 19 N 3 O 2 S 1"
xref	MassAvg: "257.35"
xref	MassMono: "257.119798"
xref	Origin: "K, M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.1603. MOD:01603 2x(15)N labeled L-lysine

Table 1605. Term [MOD:01603]
id	MOD:01603
name	2x(15)N labeled L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 2x(15)N labeled L-lysine." [PubMed:18688235, URL:http\://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=609021\|ALDRICH&N5=SEARCH_CONCAT_PNO\|BRAND_KEY&F=SPEC&lang=en_US0.000000E+000]
subset	PSI-MOD-slim
xref	DiffAvg: "1.99"
xref	DiffFormula: "(14)N -2 (15)N 2"
xref	DiffMono: "1.994070"
xref	Formula: "C 6 H 12 (15)N 2 O 1"
xref	MassAvg: "130.09"
xref	MassMono: "130.089033"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1604. MOD:01604 4x(15)N labeled L-arginine

Table 1606. Term [MOD:01604]
id	MOD:01604
name	4x(15)N labeled L-arginine
def	"A protein modification that effectively converts an L-arginine residue to 4x(15)N labeled L-arginine." [PubMed:18688235, URL:http\://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=600113\|ALDRICH&N5=SEARCH_CONCAT_PNO\|BRAND_KEY&F=SPEC&lang=en_US0.000000E+000]
subset	PSI-MOD-slim
xref	DiffAvg: "3.99"
xref	DiffFormula: "(14)N -4 (15)N 4"
xref	DiffMono: "3.988140"
xref	Formula: "C 6 H 12 (15)N 4 O 1"
xref	MassAvg: "160.09"
xref	MassMono: "160.089251"
xref	Origin: "R"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.1605. MOD:01605 5-glutamyl 2-aminoadipic acid

Table 1607. Term [MOD:01605]
id	MOD:01605
name	5-glutamyl 2-aminoadipic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl 2-aminoadipic acid." [PubMed:19620981, RESID:AA0502]
synonym	"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanedioic acid" EXACT RESID-systematic []
synonym	"5-glutamyl 2-aminoadipic acid" EXACT RESID-name []
synonym	"MOD_RES 5-glutamyl 2-aminoadipic acid" EXACT UniProt-feature []
synonym	"N2-(gamma-glutamyl)-2-aminoadipic acid" EXACT RESID-alternate []
synonym	"N2-(isoglutamyl)-2-aminoadipic acid" EXACT RESID-alternate []
xref	DiffAvg: "143.14"
xref	DiffFormula: "C 6 H 9 N 1 O 3"
xref	DiffMono: "143.058243"
xref	Formula: "C 11 H 16 N 2 O 6"
xref	MassAvg: "272.26"
xref	MassMono: "272.100836"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1606. MOD:01606 5-glutamyl 2-aminoadipic 6-phosphoric anhydride

Table 1608. Term [MOD:01606]
id	MOD:01606
name	5-glutamyl 2-aminoadipic 6-phosphoric anhydride
def	"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl 2-aminoadipic 6-phosphoric anhydride." [PubMed:19620981, RESID:AA0503]
synonym	"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)-6-oxo-6-(phosphonooxy)hexanoic acid" EXACT RESID-systematic []
synonym	"5-glutamyl 2-aminoadipic 6-phosphoric anhydride" EXACT RESID-name []
xref	DiffAvg: "223.12"
xref	DiffFormula: "C 6 H 10 N 1 O 6 P 1"
xref	DiffMono: "223.024574"
xref	Formula: "C 11 H 17 N 2 O 9 P 1"
xref	MassAvg: "352.24"
xref	MassMono: "352.067167"
xref	Origin: "E"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1607. MOD:01607 5-glutamyl allysine

Table 1609. Term [MOD:01607]
id	MOD:01607
name	5-glutamyl allysine
def	"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl allysine." [PubMed:19620981, RESID:AA0504]
synonym	"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)-6-oxohexanoic acid" EXACT RESID-systematic []
synonym	"2-(5-glutamyl)amino-6-oxohexanoic acid" EXACT RESID-alternate []
synonym	"5-glutamyl allysine" EXACT RESID-name []
synonym	"alpha-(gamma-glutamyl)allysine" EXACT RESID-alternate []
synonym	"N2-(gamma-glutamyl)allysine" EXACT RESID-alternate []
synonym	"N2-(isoglutamyl)allysine" EXACT RESID-alternate []
xref	DiffAvg: "127.14"
xref	DiffFormula: "C 6 H 9 N 1 O 2"
xref	DiffMono: "127.063329"
xref	Formula: "C 11 H 16 N 2 O 5"
xref	MassAvg: "256.26"
xref	MassMono: "256.105922"
xref	Origin: "E"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1608. MOD:01608 N2-(L-isoglutamyl)-L-lysine

Table 1610. Term [MOD:01608]
id	MOD:01608
name	N2-(L-isoglutamyl)-L-lysine
def	"A protein modification that effectively converts an L-glutamic acid residue to N2-(L-isoglutamyl)-L-lysine. This is not an isopeptide cross-link." [PubMed:19620981, RESID:AA0505]
synonym	"(2S)-6-amino-2-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"5-glutamyl N2-lysine" EXACT RESID-alternate []
synonym	"alpha-(gamma-glutamyl)lysine" EXACT RESID-alternate []
synonym	"gamma-glutamyl N2-lysine" EXACT RESID-alternate []
synonym	"MOD_RES 5-glutamyl N2-lysine" EXACT UniProt-feature []
synonym	"N2-(gamma-glutamyl)lysine" EXACT RESID-alternate []
synonym	"N2-(L-isoglutamyl)-L-lysine" EXACT RESID-name []
xref	DiffAvg: "128.18"
xref	DiffFormula: "C 6 H 12 N 2 O 1"
xref	DiffMono: "128.094963"
xref	Formula: "C 11 H 19 N 3 O 4"
xref	MassAvg: "257.29"
xref	MassMono: "257.137556"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1609. MOD:01609 7'-hydroxy-2'-alpha-mannosyl-L-tryptophan

Table 1611. Term [MOD:01609]
id	MOD:01609
name	7'-hydroxy-2'-alpha-mannosyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 7'-hydroxy-2'-alpha-mannosyl-L-tryptophan." [PubMed:19584055, RESID:AA0506]
synonym	"(2S)-2-amino-3-[7-hydroxy-2-(alpha-D-mannopyranosyl)-1H-indol-3-yl]propanoic acid" EXACT RESID-systematic []
synonym	"7'-hydroxy-2'-alpha-mannosyl-L-tryptophan" EXACT RESID-name []
synonym	"MOD_RES 7'-hydroxytryptophan" EXACT UniProt-feature []
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 N 0 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "C 17 H 20 N 2 O 7"
xref	MassAvg: "364.35"
xref	MassMono: "364.127051"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
relationship	has_functional_parent MOD:00222 2'-alpha-mannosyl-L-tryptophan ! 2'-alpha-mannosyl-L-tryptophan
relationship	has_functional_parent MOD:01664 7'-hydroxy-L-tryptophan ! 7'-hydroxy-L-tryptophan

2.1610. MOD:01610 L-threonine methyl ester

Table 1612. Term [MOD:01610]
id	MOD:01610
name	L-threonine methyl ester
def	"A protein modification that effectively converts an L-threonine residue to L-threonine methyl ester." [PubMed:19745839, RESID:AA0507]
synonym	"L-threonine methyl ester" EXACT RESID-name []
synonym	"methyl (2S,3R)-2-amino-3-hydroxybutanoate" EXACT RESID-systematic []
synonym	"methyl L-threoninate" EXACT RESID-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 5 H 10 N 1 O 3"
xref	MassAvg: "132.14"
xref	MassMono: "132.066068"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01689 alpha-carboxyl methylated residue ! alpha-carboxyl methylated residue
is_a	MOD:01803 O-methylated threonine ! O-methylated threonine

2.1611. MOD:01611 6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FMN

Table 1613. Term [MOD:01611]
id	MOD:01611
name	6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FMN
def	"A protein modification that crosslinks a cysteine and a histidine residue by forming the adduct 6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FMN." [PubMed:17935335, RESID:AA0508]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"6-(®-2-amino-2-carboxyethyl)sulfanyl-8alpha-[4-((S)-2-amino-2-carboxyethyl)imidazol-3-yl]-riboflavin 5'-trihydrogen phosphate" EXACT RESID-systematic []
synonym	"6-(S-cysteinyl)-8alpha-(N(delta)-histidyl)-FMN" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(N(pi)-histidyl)-FMN" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(N3'-histidyl)-FMN" EXACT RESID-alternate []
synonym	"6-(S-cysteinyl)-8alpha-(pros-histidyl)-FMN" EXACT RESID-alternate []
synonym	"6-(S-L-cysteinyl)-8alpha-(N3'-L-histidino)-FMN" EXACT RESID-name []
synonym	"BINDING FMN (covalent; via 2 links)" EXACT UniProt-feature []
synonym	"BINDING FMN (covalent; via 2 links, pros nitrogen)" EXACT UniProt-feature []
xref	DiffAvg: "452.32"
xref	DiffFormula: "C 17 H 17 N 4 O 9 P 1 S 0"
xref	DiffMono: "452.073315"
xref	Formula: "C 26 H 29 N 8 O 11 P 1 S 1"
xref	MassAvg: "692.60"
xref	MassMono: "692.141411"
xref	Origin: "C, H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00896 FMN modified residue ! FMN modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01621 flavin crosslinked residues ! flavin crosslinked residues

2.1612. MOD:01612 3'-iodo-L-tyrosine

Table 1614. Term [MOD:01612]
id	MOD:01612
name	3'-iodo-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3'-iodo-L-tyrosine." [ChEBI:27847, PubMed:8995307, RESID:AA0509]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3'-iodo-L-tyrosine" EXACT RESID-name []
synonym	"3-iodo-L-tyrosine" EXACT RESID-alternate []
synonym	"3-iodotyrosine" EXACT RESID-alternate []
synonym	"4-hydroxy-3-iodo-phenylalanine" EXACT RESID-alternate []
synonym	"MIT" EXACT RESID-alternate []
synonym	"MOD_RES Iodotyrosine" EXACT UniProt-feature []
xref	DiffAvg: "125.90"
xref	DiffFormula: "C 0 H -1 I 1 N 0 O 0"
xref	DiffMono: "125.896648"
xref	Formula: "C 9 H 8 I 1 N 1 O 2"
xref	MassAvg: "289.07"
xref	MassMono: "288.959976"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01228 monoiodinated tyrosine ! monoiodinated tyrosine

2.1613. MOD:01613 3',5'-diiodo-L-tyrosine

Table 1615. Term [MOD:01613]
id	MOD:01613
name	3',5'-diiodo-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3',5'-diiodo-L-tyrosine." [ChEBI:15768, PubMed:8995307, RESID:AA0510]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3',5'-diiodo-L-tyrosine" EXACT RESID-name []
synonym	"3,5-diiodo-L-tyrosine" EXACT RESID-alternate []
synonym	"3,5-diiodotyrosine" EXACT RESID-alternate []
synonym	"DIT" EXACT RESID-alternate []
synonym	"iodogorgoic acid" EXACT RESID-alternate []
synonym	"MOD_RES Diiodotyrosine" EXACT UniProt-feature []
xref	DiffAvg: "251.79"
xref	DiffFormula: "C 0 H -2 I 2 N 0 O 0"
xref	DiffMono: "251.793295"
xref	Formula: "C 9 H 7 I 2 N 1 O 2"
xref	MassAvg: "414.97"
xref	MassMono: "414.856624"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01140 diiodinated tyrosine ! diiodinated tyrosine

2.1614. MOD:01614 glycyl phospho-5'-adenosine

Table 1616. Term [MOD:01614]
id	MOD:01614
name	glycyl phospho-5'-adenosine
def	"A protein modification that effectively converts a glycine residue to glycyl phospho-5'-adenosine." [PubMed:16388576, PubMed:9632726, RESID:AA0511]
synonym	"(2-aminoacetyl)oxy-([(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy)phosphinic acid" EXACT RESID-alternate []
synonym	"([(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl)-2-aminoethanoate" EXACT RESID-alternate []
synonym	"5'-adenylic-glyinate" EXACT RESID-alternate []
synonym	"aminoacetyl [5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl hydrogen phosphate" EXACT RESID-systematic []
synonym	"glycine monoanhydride with 5'-adenylic acid" EXACT RESID-alternate []
synonym	"glycyl 5'-adenylate" EXACT RESID-alternate []
synonym	"glycyl adenosine-5'-phosphate" EXACT RESID-alternate []
synonym	"glycyl phospho-5'-adenosine" EXACT RESID-name []
synonym	"glycyladenylate" EXACT RESID-alternate []
synonym	"MOD_RES Glycyl adenylate" EXACT UniProt-feature []
xref	DiffAvg: "329.21"
xref	DiffFormula: "C 10 H 12 N 5 O 6 P 1"
xref	DiffMono: "329.052520"
xref	Formula: "C 12 H 16 N 6 O 8 P 1"
xref	MassAvg: "403.27"
xref	MassMono: "403.076723"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01165 adenylated residue ! adenylated residue

2.1615. MOD:01615 glycyl cysteine dithioester

Table 1617. Term [MOD:01615]
id	MOD:01615
name	glycyl cysteine dithioester
def	"A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a dithioester bond to form glycyl cysteine dithioester." [PubMed:11438688, PubMed:16388576, RESID:AA0512]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-[(aminoacetyl)disulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"2-(glycyldithio)alanine" EXACT RESID-alternate []
synonym	"glycyl cysteine dithioester" EXACT RESID-name []
synonym	"S-glycyl cysteine persulfide" EXACT RESID-alternate []
synonym	"S-glycyl thiocysteine" EXACT RESID-alternate []
synonym	"thioglycine cysteine disulfide" EXACT RESID-alternate []
xref	DiffAvg: "14.05"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 1"
xref	DiffMono: "13.961506"
xref	Formula: "C 5 H 7 N 2 O 2 S 2"
xref	MassAvg: "191.24"
xref	MassMono: "190.994894"
xref	Origin: "C, G"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00395 thioester crosslinked residues ! thioester crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water

2.1616. MOD:01616 trithiocystine

Table 1618. Term [MOD:01616]
id	MOD:01616
name	trithiocystine
def	"A protein modification that effectively cross-links two L-cysteine residues and adds three sulfur atoms to form trithiocystine." [PubMed:19438211, RESID:AA0513]
comment	Cross-link 2.
synonym	"(2R,2’R)-3,3'-pentasulfane-1,5-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"3,3'-pentathiobisalanine" EXACT RESID-alternate []
synonym	"bis(2-amino-2-carboxyethyl)pentasulfide" EXACT RESID-alternate []
synonym	"trithiocystine" EXACT RESID-name []
xref	DiffAvg: "94.16"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 3"
xref	DiffMono: "93.900563"
xref	Formula: "C 6 H 8 N 2 O 2 S 5"
xref	MassAvg: "300.44"
xref	MassMono: "299.918933"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01620 polysulfide crosslinked residues ! polysulfide crosslinked residues

2.1617. MOD:01617 O-(6-phosphomannosyl)-L-threonine

Table 1619. Term [MOD:01617]
id	MOD:01617
name	O-(6-phosphomannosyl)-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-(6-phosphomannosyl)-L-threonine." [PubMed:20044576, RESID:AA0514]
synonym	"(2S,3R)-2-amino-3-[6-phosphonooxy-alpha-D-mannopyranosyloxy]butanoic acid" EXACT RESID-systematic []
synonym	"O-(6-phosphomannosyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(6-phosphomannosyl)threonine" EXACT RESID-alternate []
xref	DiffAvg: "242.12"
xref	DiffFormula: "C 6 H 11 N 0 O 8 P 1"
xref	DiffMono: "242.019154"
xref	Formula: "C 10 H 18 N 1 O 10 P 1"
xref	MassAvg: "343.22"
xref	MassMono: "343.066832"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine
is_a	MOD:00595 mannosylated residue ! mannosylated residue

2.1618. MOD:01618 L-alanyl-L-isoaspartyl cyclopeptide

Table 1620. Term [MOD:01618]
id	MOD:01618
name	L-alanyl-L-isoaspartyl cyclopeptide
def	"A protein modification that effectively converts an L-alaine residue and an L-asparagine residue to L-alanyl-L-isoaspartyl cyclopeptide." [PubMed:19928958, PubMed:3207697, RESID:AA0515]
comment	Cross-link 2.
synonym	"(2S,5S)-2-methyl-3,7-dioxo-1,4-diazepane-5-carboxylic acid" EXACT RESID-systematic []
synonym	"1,4.2-anhydro(L-alanyl-L-aspartic acid)" EXACT RESID-alternate []
synonym	"CROSSLNK Alanine isoaspartyl cyclopeptide (Ala-Asn)" EXACT UniProt-feature []
synonym	"L-alanyl-L-isoaspartyl cyclopeptide" EXACT RESID-name []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 7 H 9 N 2 O 3"
xref	MassAvg: "169.16"
xref	MassMono: "169.061317"
xref	Origin: "A, N"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia

2.1619. MOD:01619 multisulfide crosslinked residues

Table 1621. Term [MOD:01619]
id	MOD:01619
name	multisulfide crosslinked residues
def	"A protein modification that crosslinks two cysteine residues by formation of a chain of two or more bonded sulfur atoms." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1620. MOD:01620 polysulfide crosslinked residues

Table 1622. Term [MOD:01620]
id	MOD:01620
name	polysulfide crosslinked residues
def	"A protein modification that crosslinks two cysteine residues by formation of a chain of three or more bonded sulfur atoms." [PubMed:18688235]
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:01619 multisulfide crosslinked residues ! multisulfide crosslinked residues

2.1621. MOD:01621 flavin crosslinked residues

Table 1623. Term [MOD:01621]
id	MOD:01621
name	flavin crosslinked residues
def	"A protein modification that crosslinks two or more amino acid residues by forming an adduct with a compound containing a flavin group." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00697 flavin modified residue ! flavin modified residue

2.1622. MOD:01622 monohydroxylated tryptophan

Table 1624. Term [MOD:01622]
id	MOD:01622
name	monohydroxylated tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to one of several monohydroxylated tryptophan residues, including 3-hydroxy-L-tryptophan and 7'-hydroxy-L-tryptophan." [OMSSA:90, UniMod:35#W]
synonym	"Oxidation" RELATED PSI-MS-label []
synonym	"oxyw" EXACT OMSSA-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 11 H 10 N 2 O 2"
xref	MassAvg: "202.21"
xref	MassMono: "202.074228"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1623. MOD:01623 1-thioglycine (C-terminal)

Table 1625. Term [MOD:01623]
id	MOD:01623
name	1-thioglycine (C-terminal)
def	"A protein modification that effectively converts a glycine residue to a C-terminal 1-thioglycine." [PubMed:11463785, PubMed:19145231, PubMed:9367957, RESID:AA0265#var]
subset	PSI-MOD-slim
xref	DiffAvg: "16.06"
xref	DiffFormula: "C 0 H 0 N 0 O -1 S 1"
xref	DiffMono: "15.977156"
xref	Formula: "C 2 H 3 N 1 S 1"
xref	MassAvg: "73.11"
xref	MassMono: "72.998620"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01625 1-thioglycine ! 1-thioglycine

2.1624. MOD:01624 (2-aminosuccinimidyl)acetic acid (Asn)

Table 1626. Term [MOD:01624]
id	MOD:01624
name	(2-aminosuccinimidyl)acetic acid (Asn)
def	"A protein modification that crosslinks an asparagine and the following glycine residue with the formation of (2-aminosuccinimidyl)acetic acid and the release of ammonia." [PubMed:10801322, PubMed:2015294, RESID:AA0441#ASN]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(2-aminosuccinimidyl)acetic acid" EXACT RESID-name []
synonym	"(3-amino-2,5-dioxo-1-pyrrolidinyl)acetic acid" EXACT RESID-alternate []
synonym	"[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]acetic acid" EXACT RESID-systematic []
synonym	"anhydroaspartyl glycine" EXACT RESID-alternate []
synonym	"aspartimide glycine" EXACT RESID-alternate []
synonym	"CROSSLNK (2-aminosuccinimidyl)acetic acid (Asn-Gly)" EXACT UniProt-feature []
synonym	"N-(2-aminosuccinyl)glycine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "G, N"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia
is_a	MOD:01628 (2-aminosuccinimidyl)acetic acid ! (2-aminosuccinimidyl)acetic acid

2.1625. MOD:01625 1-thioglycine

Table 1627. Term [MOD:01625]
id	MOD:01625
name	1-thioglycine
def	"A protein modification that effectively converts a glycine residue to 1-thioglycine." [PubMed:11463785, PubMed:9367957, RESID:AA0265]
comment	This modification occurs naturally in two forms. At an interior peptide location (MOD:00270) it exists as aminoethanethionic acid, or aminoethanethioic O-acid. At the C-terminal (MOD:01623) it exists as aminoethanethiolic acid, or aminoethanethioic S-acid [JSG].
subset	PSI-MOD-slim
synonym	"1-thioglycine" EXACT RESID-name []
synonym	"2-amino-1-sulfanylethanone" EXACT RESID-alternate []
synonym	"aminoethanethioic acid" EXACT RESID-systematic []
synonym	"aminothioacetic acid" EXACT RESID-alternate []
synonym	"Carboxy→Thiocarboxy" RELATED PSI-MS-label []
synonym	"MOD_RES 1-thioglycine" EXACT UniProt-feature []
synonym	"S(O)Gly" EXACT PSI-MOD-label []
synonym	"thiocarboxylic acid" RELATED UniMod-description []
xref	DiffAvg: "16.06"
xref	DiffFormula: "C 0 H 0 N 0 O -1 S 1"
xref	DiffMono: "15.977156"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "G"
xref	Source: "natural"
is_a	MOD:00749 sulfur substitution for oxygen ! sulfur substitution for oxygen
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.1626. MOD:01626 L-cystine

Table 1628. Term [MOD:01626]
id	MOD:01626
name	L-cystine
def	"A protein modification that forms L-cystine by forming a disulfide bond that either cross-links two peptidyl L-cysteine residues, or modifies a peptidyl cysteine with a free cysteine." [ChEBI:16283, PubMed:1988019, PubMed:2001356, PubMed:2076469, PubMed:3083866, PubMed:366603, PubMed:7918467, PubMed:8344916, RESID:AA0025]
comment	This modification occurs naturally in two forms. It exists as a disulfide cross-link of two cysteine residues (MOD:00034), or as a disulfide cross-link of a cysteine residues and a free cysteine (MOD:00765).
subset	PSI-MOD-slim
synonym	"(2R,2’R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid" RELATED RESID-misnomer []
synonym	"3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"3,3'-dithiobisalanine" EXACT RESID-alternate []
synonym	"3,3'-dithiodialanine" EXACT RESID-alternate []
synonym	"beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide" EXACT RESID-alternate []
synonym	"beta,beta'-dithiodialanine" EXACT RESID-alternate []
synonym	"bis(alpha-aminopropionic acid)-beta-disulfide" EXACT RESID-alternate []
synonym	"bis(beta-amino-beta-carboxyethyl)disulfide" EXACT RESID-alternate []
synonym	"Cys2" EXACT PSI-MOD-label []
synonym	"Cystine ((Cys)2)" EXACT DeltaMass-label []
synonym	"dicysteine" EXACT RESID-alternate []
synonym	"L-cystine" EXACT RESID-name []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "none"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1627. MOD:01627 L-cysteinyl-L-selenocysteine

Table 1629. Term [MOD:01627]
id	MOD:01627
name	L-cysteinyl-L-selenocysteine
def	"A protein modification that forms L-cysteinyl-L-selenocysteine either by the natural process of cross-linking an L-cysteine residue and an L-selenocysteine residue, or by the hypothetical process of substituting a selenium for a sulfur atom in cystine." [PubMed:12911312, PubMed:18688235]
comment	Cross-link 2.
subset	PSI-MOD-slim
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 8 N 2 O 2 S 1 Se 1"
xref	MassAvg: "251.17"
xref	MassMono: "251.947170"
xref	Origin: "C, X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1628. MOD:01628 (2-aminosuccinimidyl)acetic acid

Table 1630. Term [MOD:01628]
id	MOD:01628
name	(2-aminosuccinimidyl)acetic acid
def	"A protein modification that forms (2-aminosuccinimidyl)acetic acid by crosslinking either an aspartic acid residue or an asparagine residue with the following glycine residue." [PubMed:10801322, PubMed:18688235]
comment	Cross-link 2; this cross-link is formed by the condensation of an aspartic acid residue or an asparagine residue with the alpha-amido of the following residue.
subset	PSI-MOD-slim
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "G, X"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01944 2-aminosuccinimide ring crosslinked residues ! 2-aminosuccinimide ring crosslinked residues

2.1629. MOD:01629 cyclo[(prolylserin)-O-yl] cysteinate

Table 1631. Term [MOD:01629]
id	MOD:01629
name	cyclo[(prolylserin)-O-yl] cysteinate
def	"A protein modification that forms cyclo[(prolylserin)-O-yl] cysteinate by the natural process of cross-linking an L-cysteine residue an L-proline residue, and an L-serine residue, or by effectively modifying a cysteine residue." [PubMed:7961166, RESID:AA0489]
synonym	"(3,6-dioxopyrrolo[4,5-a]piperazin-2-yl)methyl cysteinate" EXACT RESID-alternate []
synonym	"[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]methyl (2R)-2-amino-3-sulfanylpropanoate" EXACT RESID-systematic []
synonym	"cyclo[(prolylserin)-O-yl] cysteinate" EXACT RESID-name []
synonym	"MOD_RES Cyclo[(prolylserin)-O-yl] cysteinate" EXACT UniProt-feature []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 11 H 16 N 3 O 4 S 1"
xref	MassAvg: "286.33"
xref	MassMono: "286.086152"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1630. MOD:01630 N6-(L-isoglutamyl)-L-lysine

Table 1632. Term [MOD:01630]
id	MOD:01630
name	N6-(L-isoglutamyl)-L-lysine
def	"A protein modification that effectively crosslinks either an L-glutamine residue or an L-glutamic acid residue with an L-lysine residue by an isopeptide bond to form N6-(L-isoglutamyl)-L-lysine ." [ChEBI:21863, DeltaMass:0, PubMed:2461365, PubMed:5637041, PubMed:5656070, PubMed:8598899, RESID:AA0124]
comment	Cross-link 2.
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acid" EXACT RESID-alternate []
synonym	"5-glutamyl N6-lysine" EXACT RESID-alternate []
synonym	"N alpha -(gamma-Glutamyl)-lysine" EXACT DeltaMass-label []
synonym	"N(epsilon)-(gamma-glutamyl)lysine" EXACT RESID-alternate []
synonym	"N6-(L-isoglutamyl)-L-lysine" EXACT RESID-name []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 11 H 17 N 3 O 3"
xref	MassAvg: "239.27"
xref	MassMono: "239.126991"
xref	Origin: "K, X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1631. MOD:01631 L-alanine removal

Table 1633. Term [MOD:01631]
id	MOD:01631
name	L-alanine removal
def	"A protein modification that effectively removes or replaces an L-alanine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-alanine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-71.08"
xref	DiffFormula: "C -3 H -5 N -1 O -1"
xref	DiffMono: "-71.037114"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1632. MOD:01632 L-arginine removal

Table 1634. Term [MOD:01632]
id	MOD:01632
name	L-arginine removal
def	"A protein modification that effectively removes or replaces an L-arginine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-arginine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-156.19"
xref	DiffFormula: "C -6 H -12 N -4 O -1"
xref	DiffMono: "-156.101111"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1633. MOD:01633 L-asparagine removal

Table 1635. Term [MOD:01633]
id	MOD:01633
name	L-asparagine removal
def	"A protein modification that effectively removes or replaces an L-asparagine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-asparagine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-114.10"
xref	DiffFormula: "C -4 H -6 N -2 O -2"
xref	DiffMono: "-114.042927"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1634. MOD:01634 L-aspartic acid removal

Table 1636. Term [MOD:01634]
id	MOD:01634
name	L-aspartic acid removal
def	"A protein modification that effectively removes or replaces an L-aspartic acid." [PubMed:18688235]
comment	This represents the loss or replacement of an L-aspartic acid residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-115.09"
xref	DiffFormula: "C -4 H -5 N -1 O -3"
xref	DiffMono: "-115.026943"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1635. MOD:01635 L-cysteine removal

Table 1637. Term [MOD:01635]
id	MOD:01635
name	L-cysteine removal
def	"A protein modification that effectively removes or replaces an L-cysteine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-cysteine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-103.14"
xref	DiffFormula: "C -3 H -5 N -1 O -1 S -1"
xref	DiffMono: "-103.009185"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1636. MOD:01636 L-glutamic acid removal

Table 1638. Term [MOD:01636]
id	MOD:01636
name	L-glutamic acid removal
def	"A protein modification that effectively removes or replaces an L-glutamic acid." [PubMed:18688235]
comment	This represents the loss or replacement of an L-glutamic acid residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-129.12"
xref	DiffFormula: "C -5 H -7 N -1 O -3"
xref	DiffMono: "-129.042593"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1637. MOD:01637 L-glutamine removal

Table 1639. Term [MOD:01637]
id	MOD:01637
name	L-glutamine removal
def	"A protein modification that effectively removes or replaces an L-glutamine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-glutamine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-128.13"
xref	DiffFormula: "C -5 H -8 N -2 O -2"
xref	DiffMono: "-128.058578"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1638. MOD:01638 glycine removal

Table 1640. Term [MOD:01638]
id	MOD:01638
name	glycine removal
def	"A protein modification that effectively removes or replaces a glycine." [PubMed:18688235]
comment	This represents the loss or replacement of an glycine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-57.05"
xref	DiffFormula: "C -2 H -3 N -1 O -1"
xref	DiffMono: "-57.021464"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1639. MOD:01639 L-histidine removal

Table 1641. Term [MOD:01639]
id	MOD:01639
name	L-histidine removal
def	"A protein modification that effectively removes or replaces an L-histidine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-histidine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-137.14"
xref	DiffFormula: "C -6 H -7 N -3 O -1"
xref	DiffMono: "-137.058912"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1640. MOD:01640 L-isoleucine removal

Table 1642. Term [MOD:01640]
id	MOD:01640
name	L-isoleucine removal
def	"A protein modification that effectively removes or replaces an L-isoleucine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-isoleucine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-113.16"
xref	DiffFormula: "C -6 H -11 N -1 O -1"
xref	DiffMono: "-113.084064"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1641. MOD:01641 L-leucine removal

Table 1643. Term [MOD:01641]
id	MOD:01641
name	L-leucine removal
def	"A protein modification that effectively removes or replaces an L-leucine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-leucine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-113.16"
xref	DiffFormula: "C -6 H -11 N -1 O -1"
xref	DiffMono: "-113.084064"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "L"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1642. MOD:01642 L-lysine removal

Table 1644. Term [MOD:01642]
id	MOD:01642
name	L-lysine removal
def	"A protein modification that effectively removes or replaces an L-lysine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-lysine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-128.18"
xref	DiffFormula: "C -6 H -12 N -2 O -1"
xref	DiffMono: "-128.094963"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1643. MOD:01643 L-methionine removal

Table 1645. Term [MOD:01643]
id	MOD:01643
name	L-methionine removal
def	"A protein modification that effectively removes or replaces an L-methionine." [OMSSA:9, PubMed:3327521, UniMod:765]
comment	This represents the loss or replacement of an L-methionine residue in a polypeptide, including initiator methionine removal in eukaryotes. It may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution [JSG].
subset	PSI-MOD-slim
synonym	"Met-loss" RELATED UniMod-interim []
synonym	"ntermmcleave" EXACT OMSSA-label []
xref	DiffAvg: "-131.19"
xref	DiffFormula: "C -5 H -9 N -1 O -1 S -1"
xref	DiffMono: "-131.040485"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1644. MOD:01644 L-phenylalanine removal

Table 1646. Term [MOD:01644]
id	MOD:01644
name	L-phenylalanine removal
def	"A protein modification that effectively removes or replaces an L-phenylalanine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-phenylalanine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-147.18"
xref	DiffFormula: "C -9 H -9 N -1 O -1"
xref	DiffMono: "-147.068414"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "F"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1645. MOD:01645 L-proline removal

Table 1647. Term [MOD:01645]
id	MOD:01645
name	L-proline removal
def	"A protein modification that effectively removes or replaces an L-proline." [PubMed:18688235]
comment	This represents the loss or replacement of an L-proline residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-97.12"
xref	DiffFormula: "C -5 H -7 N -1 O -1"
xref	DiffMono: "-97.052764"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1646. MOD:01646 L-serine removal

Table 1648. Term [MOD:01646]
id	MOD:01646
name	L-serine removal
def	"A protein modification that effectively removes or replaces an L-serine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-serine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-87.08"
xref	DiffFormula: "C -3 H -5 N -1 O -2"
xref	DiffMono: "-87.032028"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1647. MOD:01647 L-threonine removal

Table 1649. Term [MOD:01647]
id	MOD:01647
name	L-threonine removal
def	"A protein modification that effectively removes or replaces an L-threonine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-threonine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-101.10"
xref	DiffFormula: "C -4 H -7 N -1 O -2"
xref	DiffMono: "-101.047678"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1648. MOD:01648 L-tryptophan removal

Table 1650. Term [MOD:01648]
id	MOD:01648
name	L-tryptophan removal
def	"A protein modification that effectively removes or replaces an L-tryptophan." [PubMed:18688235]
comment	This represents the loss or replacement of an L-tryptophan residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-186.21"
xref	DiffFormula: "C -11 H -10 N -2 O -1"
xref	DiffMono: "-186.079313"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1649. MOD:01649 L-tyrosine removal

Table 1651. Term [MOD:01649]
id	MOD:01649
name	L-tyrosine removal
def	"A protein modification that effectively removes or replaces an L-tyrosine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-tyrosine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-163.18"
xref	DiffFormula: "C -9 H -9 N -1 O -2"
xref	DiffMono: "-163.063329"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1650. MOD:01650 L-valine removal

Table 1652. Term [MOD:01650]
id	MOD:01650
name	L-valine removal
def	"A protein modification that effectively removes or replaces an L-valine." [PubMed:18688235]
comment	This represents the loss or replacement of an L-valine residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	DiffAvg: "-99.13"
xref	DiffFormula: "C -5 H -9 N -1 O -1"
xref	DiffMono: "-99.068414"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01651 natural, standard, encoded residue removal ! natural, standard, encoded residue removal

2.1651. MOD:01651 natural, standard, encoded residue removal

Table 1653. Term [MOD:01651]
id	MOD:01651
name	natural, standard, encoded residue removal
def	"A protein modification that effectively removes or replaces a natural, standard, encoded residue." [PubMed:18688235]
comment	This represents the loss or replacement of an encoded residue in a polypeptide, and may be combined with the formula or mass of another entry that is the replacement residue to represent a mutation or substitution.
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00009 natural residue ! natural residue

2.1652. MOD:01652 sulfonyl halide reagent derivatized residue

Table 1654. Term [MOD:01652]
id	MOD:01652
name	sulfonyl halide reagent derivatized residue
def	"A protein modification that is produced by formation of an adduct with a sulfonyl halide compound used as a reagent." [PubMed:18688235]
comment	These reagents typically react with N6-amino group of lysine residues and a free alpha-amino group of a peptide.
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1653. MOD:01653 dansyl chloride derivatized residue

Table 1655. Term [MOD:01653]
id	MOD:01653
name	dansyl chloride derivatized residue
def	"A protein modification that is produced by formation of an adduct with 5-dimethylaminonaphthalene-1-sulfonyl chloride, dansyl chloride." [DeltaMass:0, UniMod:139]
synonym	"5-dimethylaminonaphthalene-1-sulfonyl" RELATED UniMod-description []
synonym	"Dansyl" RELATED PSI-MS-label []
synonym	"Dansyl (Dns)" EXACT DeltaMass-label []
synonym	"DansylRes" EXACT PSI-MOD-label []
xref	DiffAvg: "233.29"
xref	DiffFormula: "C 12 H 11 N 1 O 2 S 1"
xref	DiffMono: "233.051050"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01652 sulfonyl halide reagent derivatized residue ! sulfonyl halide reagent derivatized residue

2.1654. MOD:01654 N6-Dansyl derivatized lysine

Table 1656. Term [MOD:01654]
id	MOD:01654
name	N6-Dansyl derivatized lysine
def	"A protein modification that is produced by reaction with 5-dimethylaminonaphthalene-1-sulfonyl chloride, dansyl chloride, to form N6-Dansyl-lysine." [UniMod:139#K]
synonym	"5-dimethylaminonaphthalene-1-sulfonyl" RELATED UniMod-description []
synonym	"Dansyl" RELATED PSI-MS-label []
synonym	"N6DansylLys" EXACT PSI-MOD-label []
xref	DiffAvg: "233.29"
xref	DiffFormula: "C 12 H 11 N 1 O 2 S 1"
xref	DiffMono: "233.051050"
xref	Formula: "C 18 H 23 N 3 O 3 S 1"
xref	MassAvg: "361.46"
xref	MassMono: "361.146013"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01653 dansyl chloride derivatized residue ! dansyl chloride derivatized residue

2.1655. MOD:01655 alpha-amino-Dansyl derivatized residue

Table 1657. Term [MOD:01655]
id	MOD:01655
name	alpha-amino-Dansyl derivatized residue
def	"A protein modification that is produced by reaction with 5-dimethylaminonaphthalene-1-sulfonyl chloride, dansyl chloride, to form an alpha-amino-Dansyl-derivatized residue." [UniMod:139#N-term]
synonym	"5-dimethylaminonaphthalene-1-sulfonyl" RELATED UniMod-description []
synonym	"Dansyl" RELATED PSI-MS-label []
synonym	"N2DansylRes" EXACT PSI-MOD-label []
xref	DiffAvg: "233.29"
xref	DiffFormula: "C 12 H 11 N 1 O 2 S 1"
xref	DiffMono: "233.051050"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01653 dansyl chloride derivatized residue ! dansyl chloride derivatized residue

2.1656. MOD:01656 Dabsyl chloride derivatized residue

Table 1658. Term [MOD:01656]
id	MOD:01656
name	Dabsyl chloride derivatized residue
def	"A protein modification that is produced by formation of an adduct with 4-(4-dimethylaminophenylazo)benzenesulfonyl chloride, Dabsyl chloride." [PubMed:18688235]
synonym	"4-([4-(dimethylamino)phenyl]diazenyl)benzenesulfonyl" EXACT PSI-MOD-alternate []
synonym	"DabsylRes" EXACT PSI-MOD-label []
xref	DiffAvg: "287.34"
xref	DiffFormula: "C 14 H 13 N 3 O 2 S 1"
xref	DiffMono: "287.072848"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01652 sulfonyl halide reagent derivatized residue ! sulfonyl halide reagent derivatized residue

2.1657. MOD:01657 N6-Dabsyl derivatized lysine

Table 1659. Term [MOD:01657]
id	MOD:01657
name	N6-Dabsyl derivatized lysine
def	"A protein modification that is produced by reaction with 4-(4-dimethylaminophenylazo)benzenesulfonyl chloride, dabsyl chloride, to form N6-Dabsyl-lysine." [PubMed:18688235]
synonym	"N6-[4-([4-(dimethylamino)phenyl]diazenyl)benzenesulfonyl]lysine" EXACT PSI-MOD-alternate []
synonym	"N6DabsylLys" EXACT PSI-MOD-label []
xref	DiffAvg: "287.34"
xref	DiffFormula: "C 14 H 13 N 3 O 2 S 1"
xref	DiffMono: "287.072848"
xref	Formula: "C 20 H 25 N 5 O 3 S 1"
xref	MassAvg: "415.51"
xref	MassMono: "415.167811"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01656 Dabsyl chloride derivatized residue ! Dabsyl chloride derivatized residue

2.1658. MOD:01658 alpha-amino-Dabsyl derivatized residue

Table 1660. Term [MOD:01658]
id	MOD:01658
name	alpha-amino-Dabsyl derivatized residue
def	"A protein modification that is produced by reaction with 4-(4-dimethylaminophenylazo)benzenesulfonyl chloride, dabsyl chloride, to form an alpha-amino-Dabsyl-derivatized residue." [PubMed:18688235]
synonym	"N2DabsylRes" EXACT PSI-MOD-label []
xref	DiffAvg: "287.34"
xref	DiffFormula: "C 14 H 13 N 3 O 2 S 1"
xref	DiffMono: "287.072848"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01656 Dabsyl chloride derivatized residue ! Dabsyl chloride derivatized residue

2.1659. MOD:01659 Uniblue A derivatized residue

Table 1661. Term [MOD:01659]
id	MOD:01659
name	Uniblue A derivatized residue
def	"A protein modification that is produced by formation of an adduct with 1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate, Uniblue A." [PubMed:18688235]
comment	This reagent has a reactive sulfonyl vinyl and typically reacts with the free thiol group of cysteine residues.
synonym	"1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid" EXACT PSI-MOD-alternate []
synonym	"1-amino-9,10-dioxo-4-{[3-(vinylsulfonyl)phenyl]amino}-9,10-dihydroanthracene-2-sulfonic acid" EXACT PSI-MOD-alternate []
synonym	"Uniblue A" EXACT PSI-MOD-alternate []
synonym	"UniblueARes" EXACT PSI-MOD-label []
xref	DiffAvg: "484.50"
xref	DiffFormula: "C 22 H 16 N 2 O 7 S 2"
xref	DiffMono: "484.039893"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1660. MOD:01660 Uniblue A derivatized cysteine

Table 1662. Term [MOD:01660]
id	MOD:01660
name	Uniblue A derivatized cysteine
def	"A protein modification that is produced by reaction with 1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate, Uniblue A, to form Uniblue A cysteine adduct." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate" EXACT PSI-MOD-alternate []
synonym	"1-amino-9,10-dioxo-4-{[3-(vinylsulfonyl)phenyl]amino}-9,10-dihydroanthracene-2-sulfonate" EXACT PSI-MOD-alternate []
synonym	"SUniblueACys" EXACT PSI-MOD-label []
synonym	"Uniblue A" EXACT PSI-MOD-alternate []
xref	DiffAvg: "484.50"
xref	DiffFormula: "C 22 H 16 N 2 O 7 S 2"
xref	DiffMono: "484.039893"
xref	Formula: "C 25 H 21 N 3 O 8 S 3"
xref	MassAvg: "587.64"
xref	MassMono: "587.049078"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01659 Uniblue A derivatized residue ! Uniblue A derivatized residue

2.1661. MOD:01661 pyruvic acid (Tyr)

Table 1663. Term [MOD:01661]
id	MOD:01661
name	pyruvic acid (Tyr)
def	"A protein modification that effectively converts an L-tyrosine residue to pyruvic acid." [PubMed:10085076, PubMed:3042771, PubMed:500639, PubMed:8464063, RESID:AA0127#TYR]
synonym	"2-oxopropanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES Pyruvic acid (Tyr)" EXACT UniProt-feature []
synonym	"pyruvic acid" EXACT RESID-name []
xref	DiffAvg: "-93.13"
xref	DiffFormula: "C -6 H -7 N -1 O 0"
xref	DiffMono: "-93.057849"
xref	Formula: "C 3 H 3 O 2"
xref	MassAvg: "71.06"
xref	MassMono: "71.013304"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01154 pyruvic acid ! pyruvic acid

2.1662. MOD:01662 N5-(ADP-ribosyl)-L-glutamine

Table 1664. Term [MOD:01662]
id	MOD:01662
name	N5-(ADP-ribosyl)-L-glutamine
def	"A protein modification that effectively converts an L-glutamine residue to N5-(ADP-ribosyl)-L-glutamine." [PubMed:20185726, RESID:AA0518]
synonym	"(S)-2-amino-4-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]amino)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"N5-(ADP-ribosyl)-L-glutamine" EXACT RESID-name []
synonym	"N5-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-glutamine" EXACT RESID-alternate []
synonym	"N5-alpha-D-ribofuranosyl-L-glutamine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 20 H 29 N 7 O 15 P 2"
xref	MassAvg: "669.43"
xref	MassMono: "669.119687"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.1663. MOD:01663 O-(ADP-ribosyl)-L-threonine

Table 1665. Term [MOD:01663]
id	MOD:01663
name	O-(ADP-ribosyl)-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-(ADP-ribosyl)-L-threonine." [PubMed:20185726, RESID:AA0519]
synonym	"(S)-2-amino-3-([adenosine 5'-(trihydrogen diphosphate) 5'→5'-ester with alpha-D-ribofuranosyl]oxy)-butanoic acid" EXACT RESID-systematic []
synonym	"O-(ADP-ribosyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(ADP-ribosyl)-L-threonine" EXACT RESID-alternate []
synonym	"O3-[alpha-D-ribofuranoside 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-threonine" EXACT RESID-alternate []
synonym	"O3-alpha-D-ribofuranosyl-L-threonine 5'→5'-ester with adenosine 5'-(trihydrogen diphosphate)" EXACT RESID-alternate []
xref	DiffAvg: "541.30"
xref	DiffFormula: "C 15 H 21 N 5 O 13 P 2"
xref	DiffMono: "541.061109"
xref	Formula: "C 19 H 28 N 6 O 15 P 2"
xref	MassAvg: "642.41"
xref	MassMono: "642.108787"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00752 adenosine diphosphoribosyl (ADP-ribosyl) modified residue ! adenosine diphosphoribosyl (ADP-ribosyl) modified residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1664. MOD:01664 7'-hydroxy-L-tryptophan

Table 1666. Term [MOD:01664]
id	MOD:01664
name	7'-hydroxy-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to a 7'-hydroxy-L-tryptophan." [PubMed:20223990, RESID:AA0520]
synonym	"(2S)-2-amino-3-(7-hydroxy-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"7'-hydroxy-L-tryptophan" EXACT RESID-name []
synonym	"7-hydroxy-L-tryptophan" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 11 H 10 N 2 O 2"
xref	MassAvg: "202.21"
xref	MassMono: "202.074228"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01622 monohydroxylated tryptophan ! monohydroxylated tryptophan

2.1665. MOD:01665 N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-valine

Table 1667. Term [MOD:01665]
id	MOD:01665
name	N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-valine
def	"A protein modification that effectively crosslinks an N-terminal L-valine residue and a strand of DNA at the C-1 of a ribose, freeing the nucleotide base and forming N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-valine." [PubMed:20185759, RESID:AA0521]
synonym	"(2S)-2-[(3R,4R)-3,4-dihydroxy-5-(phosphonooxy)pentylidene]amino-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE Schiff-base intermediate with DNA; via amino nitrogen" EXACT UniProt-feature []
synonym	"DNA glycosylase valine Schiff base intermediate" EXACT RESID-alternate []
synonym	"N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-valine" EXACT RESID-name []
xref	DiffAvg: "178.08"
xref	DiffFormula: "C 5 H 7 N 0 O 5 P 1"
xref	DiffMono: "178.003110"
xref	Formula: "C 10 H 17 N 1 O 6 P 1"
xref	MassAvg: "278.22"
xref	MassMono: "278.079349"
xref	Origin: "V"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00750 deoxyribonucleic acid linked residue ! deoxyribonucleic acid linked residue
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue

2.1666. MOD:01666 epicocconone derivatized residue

Table 1668. Term [MOD:01666]
id	MOD:01666
name	epicocconone derivatized residue
def	"A protein modification that is produced by formation of an adduct with epicocconone." [PubMed:18688235]
synonym	"(6S,9aS)-6-(hydroxymethyl)-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraen-1-yl]-9a-methyl-5,6-dihydro-2H-furo[3,2-g]isochromene-2,9(9aH)-dione" EXACT PSI-MOD-alternate []
synonym	"Deep Purple" EXACT PSI-MOD-alternate []
synonym	"LavaPurple" EXACT PSI-MOD-alternate []
synonym	"Lightning Fast" EXACT PSI-MOD-alternate []
xref	DiffAvg: "410.42"
xref	DiffFormula: "C 23 H 22 O 7"
xref	DiffMono: "410.136553"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1667. MOD:01667 N6-epicoccononyl lysine adduct

Table 1669. Term [MOD:01667]
id	MOD:01667
name	N6-epicoccononyl lysine adduct
def	"A protein modification that is produced by formation of an adduct with epicocconone." [PubMed:18688235]
synonym	"(6Z,7aS)-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraen-1-yl]-7a-methyl-6-[([(1S)-1-amino-1-carboxylpentyl]amino)methylidene]-5-[(2S)-2,3-dihydroxypropyl]-1-benzofuran-2,7(6H,7aH)-dione" EXACT PSI-MOD-alternate []
synonym	"DeepPurple" EXACT PSI-MOD-alternate []
synonym	"LavaPurple" EXACT PSI-MOD-alternate []
synonym	"Lightning Fast" EXACT PSI-MOD-alternate []
xref	DiffAvg: "410.42"
xref	DiffFormula: "C 23 H 22 O 7"
xref	DiffMono: "410.136553"
xref	Formula: "C 29 H 34 N 2 O 8"
xref	MassAvg: "538.60"
xref	MassMono: "538.231516"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01666 epicocconone derivatized residue ! epicocconone derivatized residue

2.1668. MOD:01668 O4-(8alpha-FAD)-L-aspartate

Table 1670. Term [MOD:01668]
id	MOD:01668
name	O4-(8alpha-FAD)-L-aspartate
def	"A protein modification that effectively converts an L-aspartic acid residue to O4-(8alpha-FAD)-L-aspartate." [PubMed:20080101, RESID:AA0522]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-4-oxo-4-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'→5'-ester with adenosine]oxybutanoic acid" EXACT RESID-systematic []
synonym	"8alpha-[(4-aspartyl)oxy]FAD" EXACT RESID-alternate []
synonym	"O4-(8alpha-FAD)-L-aspartate" EXACT RESID-name []
xref	DiffAvg: "783.54"
xref	DiffFormula: "C 27 H 31 N 9 O 15 P 2"
xref	DiffMono: "783.141485"
xref	Formula: "C 31 H 36 N 10 O 18 P 2"
xref	MassAvg: "898.63"
xref	MassMono: "898.168428"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00895 FAD modified residue ! FAD modified residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1669. MOD:01669 trimethyl-L-arginine

Table 1671. Term [MOD:01669]
id	MOD:01669
name	trimethyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N(omega),N(omega),N'(omega)-trimethyl-L-arginine." [OMSSA:117, PubMed:11704273, PubMed:602668, RESID:AA0523, UniMod:37#R]
synonym	"(2S)-2-amino-5-([(dimethylamino)(methylamino)methylidene]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-amino-5-([(dimethylamino)(methylimino)methyl]amino)pentanoic acid" EXACT RESID-alternate []
synonym	"2-[(4S)-4-amino-5-oxopentyl]-1,1,3-trimethylguanidine" EXACT RESID-alternate []
synonym	"N(G)-trimethylarginine" EXACT RESID-alternate []
synonym	"N5-[(dimethylamino)(imino)methyl]ornithine" EXACT RESID-alternate []
synonym	"NoNoNo’Me3Arg" EXACT PSI-MOD-label []
synonym	"omega-N,omega-N,omega-N'-trimethyl-L-arginine" EXACT RESID-name []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
synonym	"trimethylationr" EXACT OMSSA-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046950"
xref	Formula: "C 9 H 18 N 4 O 1"
xref	MassAvg: "198.27"
xref	MassMono: "198.148061"
xref	Origin: "R"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00430 trimethylated residue ! trimethylated residue
is_a	MOD:00602 N-methylated residue ! N-methylated residue
is_a	MOD:00658 methylated arginine ! methylated arginine

2.1670. MOD:01670 N6-chloro-L-lysine

Table 1672. Term [MOD:01670]
id	MOD:01670
name	N6-chloro-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine." [PubMed:16091367, PubMed:16195462, PubMed:17260957, RESID:AA0524]
synonym	"(2S)-2-amino-6-(chloroamino)hexanoic acid" EXACT RESID-systematic []
synonym	"epsilon-chlorolysine" EXACT RESID-alternate []
synonym	"lysine chloramine" EXACT RESID-alternate []
synonym	"N(zeta)-chlorolysine" EXACT RESID-alternate []
synonym	"N6-chloro-L-lysine" EXACT RESID-name []
synonym	"N6ClLys" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 6 Cl 1 H 11 N 2 O 1"
xref	MassAvg: "162.62"
xref	MassMono: "162.055991"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01672 halogenated lysine ! halogenated lysine
is_a	MOD:01911 monochlorinated residue ! monochlorinated residue

2.1671. MOD:01671 O-(L-isoaspartyl)-L-threonine (active site intermediate)

Table 1673. Term [MOD:01671]
id	MOD:01671
name	O-(L-isoaspartyl)-L-threonine (active site intermediate)
def	"A protein modification that effectively converts an L-threonine residue to O-(L-isoaspartyl)-L-threonine, using free L-asparagine and releasing ammonia." [PubMed:8706862, RESID:AA0525#THR]
comment	This is a threonine active intermediate and not an ester cross-link of peptides [JSG].
synonym	"(2S)-2-amino-4-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-3-amino-3-carboxypropanoyl]oxy)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE O-isoaspartyl threonine intermediate" EXACT UniProt-feature []
synonym	"O(beta)-(beta-aspartyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoaspartyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoaspartyl)-threonine" EXACT RESID-alternate []
xref	DiffAvg: "115.09"
xref	DiffFormula: "C 4 H 5 N 1 O 3"
xref	DiffMono: "115.026943"
xref	Formula: "C 8 H 12 N 2 O 5"
xref	MassAvg: "216.19"
xref	MassMono: "216.074621"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00671 O-acylated residue ! O-acylated residue
is_a	MOD:01978 O-(L-isoaspartyl)-L-threonine ! O-(L-isoaspartyl)-L-threonine

2.1672. MOD:01672 halogenated lysine

Table 1674. Term [MOD:01672]
id	MOD:01672
name	halogenated lysine
def	"A protein modification that effectively substitutes a hydrogen atom of an L-lysine residue with a halogen atom." [PubMed:18688235]
xref	Origin: "K"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00694 halogen containing residue ! halogen containing residue

2.1673. MOD:01673 N-acetylaminohexosylated residue

Table 1675. Term [MOD:01673]
id	MOD:01673
name	N-acetylaminohexosylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an N-acetylaminohexose group through a glycosidic bond." [UniMod:43]
subset	PSI-MOD-slim
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"HexNAcRes" EXACT PSI-MOD-label []
synonym	"N-Acetylhexosamine" RELATED UniMod-description []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00436 N-acetylhexosaminylated ! N-acetylhexosaminylated

2.1674. MOD:01674 N4-(N-acetylamino)hexosyl-L-asparagine

Table 1676. Term [MOD:01674]
id	MOD:01674
name	N4-(N-acetylamino)hexosyl-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-(N-acetaminohexosyl)-L-asparagine." [OMSSA:182, UniMod:43#N]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)amino-4-oxobutanoic acid" EXACT PSI-MOD-alternate []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"HexNAcAsn" EXACT PSI-MOD-label []
synonym	"hexNAcN" EXACT OMSSA-label []
synonym	"N-Acetylhexosamine" RELATED UniMod-description []
synonym	"N4-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)-L-asparagine" EXACT PSI-MOD-alternate []
synonym	"N4-(2-acetylamino-2-deoxy-beta-D-hexopyranosyl)-L-asparagine" EXACT PSI-MOD-alternate []
synonym	"N4-(N-acetylhexosaminyl)asparagine" EXACT PSI-MOD-alternate []
synonym	"N4-asparagine-beta-N-acetylhexosaminide" EXACT PSI-MOD-alternate []
synonym	"N4-glycosyl-L-asparagine" EXACT PSI-MOD-alternate []
synonym	"N4-glycosylasparagine" EXACT PSI-MOD-alternate []
synonym	"N4HexNAcAsn" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 19 N 3 O 7"
xref	MassAvg: "317.30"
xref	MassMono: "317.122300"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00160 N4-glycosyl-L-asparagine ! N4-glycosyl-L-asparagine
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.1675. MOD:01675 O-(N-acetylamino)hexosyl-L-serine

Table 1677. Term [MOD:01675]
id	MOD:01675
name	O-(N-acetylamino)hexosyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-(N-acetylaminohexosyl)-L-serine." [OMSSA:184, UniMod:43#S]
subset	PSI-MOD-slim
synonym	"(S)-2-amino-3-(2-acetamido-2-deoxy-beta-D-hexopyranosyloxy)propanoic acid" EXACT PSI-MOD-alternate []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"hexNAcS" EXACT OMSSA-label []
synonym	"N-Acetylhexosamine" RELATED UniMod-description []
synonym	"O-(2-acetylamino-2-deoxy-beta-D-hexopyranosyl)-L-serine" EXACT PSI-MOD-alternate []
synonym	"O-(N-acetylhexosaminyl)serine" EXACT PSI-MOD-alternate []
synonym	"O-glycosylserine" EXACT PSI-MOD-alternate []
synonym	"O-seryl-beta-N-acetylhexosaminide" EXACT PSI-MOD-alternate []
synonym	"O3-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)-L-serine" EXACT PSI-MOD-alternate []
synonym	"OHexNAcSer" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 11 H 18 N 2 O 7"
xref	MassAvg: "290.27"
xref	MassMono: "290.111401"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.1676. MOD:01676 O-(N-acetylamino)hexosyl-L-threonine

Table 1678. Term [MOD:01676]
id	MOD:01676
name	O-(N-acetylamino)hexosyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O3-(N-acetylaminohexosyl)-L-threonine." [OMSSA:185, UniMod:43#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-(alpha-D-2-acetamido-2-deoxyhexopyranosyloxy)butanoic acid" EXACT PSI-MOD-alternate []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"hexNAcT" EXACT OMSSA-label []
synonym	"N-Acetylhexosamine" RELATED UniMod-description []
synonym	"O-(N-acetylhexcosaminyl)-L-threonine" EXACT PSI-MOD-alternate []
synonym	"O-glycosylthreonine" EXACT PSI-MOD-alternate []
synonym	"O3-(N-acetylhexosaminyl)threonine" EXACT PSI-MOD-alternate []
synonym	"OHexNAcThr" EXACT PSI-MOD-label []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 12 H 20 N 2 O 7"
xref	MassAvg: "304.30"
xref	MassMono: "304.127051"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00005 O-glycosyl-L-threonine ! O-glycosyl-L-threonine
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.1677. MOD:01677 O4-(N-acetylamino)hexosyl-L-hydroxyproline

Table 1679. Term [MOD:01677]
id	MOD:01677
name	O4-(N-acetylamino)hexosyl-L-hydroxyproline
def	"A protein modification that effectively converts an L-proline residue to O4-(N-acetylamino)hexosyl-L-hydroxyproline." [PubMed:18688235]
comment	secondary to RESID:AA0030
subset	PSI-MOD-slim
synonym	"(2S,4R)-4-[2-acetamido-2-deoxy-alpha-D-hexopyranosyloxy]pyrrolidine-2-carboxylic acid" EXACT PSI-MOD-alternate []
synonym	"4-(N-acetylhexosaminyloxy)proline" EXACT PSI-MOD-alternate []
synonym	"4-[(2-N-acetylamino)-alpha-D-hexopyranosyl]oxyproline" EXACT PSI-MOD-alternate []
synonym	"alpha-2-(N-acetylamino)hexopyranosyl-4-hydroxyproline" EXACT PSI-MOD-alternate []
synonym	"HexNAc" RELATED PSI-MS-label []
synonym	"O4-glycosyl-hydroxyproline" EXACT PSI-MOD-alternate []
synonym	"O4HexNAcHyPro" EXACT PSI-MOD-label []
xref	DiffAvg: "219.19"
xref	DiffFormula: "C 8 H 13 N 1 O 6"
xref	DiffMono: "219.074287"
xref	Formula: "C 13 H 20 N 2 O 7"
xref	MassAvg: "316.31"
xref	MassMono: "316.127051"
xref	Origin: "P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01673 N-acetylaminohexosylated residue ! N-acetylaminohexosylated residue

2.1678. MOD:01678 N6-carbamoyl-L-lysine

Table 1680. Term [MOD:01678]
id	MOD:01678
name	N6-carbamoyl-L-lysine
def	"A protein modification that effectively coverts L-lysine to N6-carbamoyl-L-lysine." [DeltaMass:56, OMSSA:31, PubMed:10978403, PubMed:12203680, UniMod:5#K]
comment	This modification can be produced by hydrogen cyanate, either as a reagent or as released by urea degradation in solution [JSG].
subset	PSI-MOD-slim
synonym	"2-amino-6-ureido-hexanoic acid" EXACT PSI-MOD-alternate []
synonym	"Carbamyl" RELATED UniMod-interim []
synonym	"Carbamylation" RELATED UniMod-description []
synonym	"carbamylk" EXACT OMSSA-label []
synonym	"homocitrulline" EXACT PSI-MOD-alternate []
synonym	"N6-(aminocarbonyl)-L-lysine" EXACT PSI-MOD-alternate []
synonym	"N6CbmLys" EXACT PSI-MOD-label []
xref	DiffAvg: "43.02"
xref	DiffFormula: "C 1 H 1 N 1 O 1"
xref	DiffMono: "43.005814"
xref	Formula: "C 7 H 13 N 3 O 2"
xref	MassAvg: "171.20"
xref	MassMono: "171.100777"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00398 carbamoylated residue ! carbamoylated residue

2.1679. MOD:01679 alpha-aminocarbamoylated residue

Table 1681. Term [MOD:01679]
id	MOD:01679
name	alpha-aminocarbamoylated residue
def	"A protein modification that effectively replaces a residue alpha amino or imino hydrogen with a carbamoyl group." [DeltaMass:56, OMSSA:32, PubMed:10978403, PubMed:12203680, UniMod:5#N-term]
comment	This modification can be produced by hydrogen cyanate, either as a reagent or as released by urea degradation. This modification effectively blocks Edman degradation, and because it can dehydrate to a cyanate group and react with another peptide N-terminal, it can effectively block two peptide molecules [JSG].
subset	PSI-MOD-slim
synonym	"Carbamyl" RELATED UniMod-interim []
synonym	"Carbamylation" RELATED UniMod-description []
synonym	"N2CbmRes" EXACT PSI-MOD-label []
synonym	"ntermcarbamyl" EXACT OMSSA-label []
xref	DiffAvg: "43.02"
xref	DiffFormula: "C 1 H 1 N 1 O 1"
xref	DiffMono: "43.005814"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00398 carbamoylated residue ! carbamoylated residue

2.1680. MOD:01680 alpha-amino monomethylated residue

Table 1682. Term [MOD:01680]
id	MOD:01680
name	alpha-amino monomethylated residue
def	"A protein modification that effectively replaces one residue alpha amino or imino hydrogen with one methyl group." [OMSSA:11, OMSSA:76, UniMod:34#N-term]
comment	Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
subset	PSI-MOD-slim
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"N2Me1Res" EXACT PSI-MOD-label []
synonym	"ntermmethyl" EXACT OMSSA-label []
synonym	"ntermpepmethyl" EXACT OMSSA-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1681. MOD:01681 monomethylated L-aspartic acid

Table 1683. Term [MOD:01681]
id	MOD:01681
name	monomethylated L-aspartic acid
def	"A protein modification that effectively replaces one hydrogen atom of an L-aspartic acid residue with one methyl group." [OMSSA:16, UniMod:34#D]
synonym	"Me1Asp" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"methyld" EXACT OMSSA-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 5 H 7 N 1 O 3"
xref	MassAvg: "129.12"
xref	MassMono: "129.042593"
xref	Origin: "D"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00887 methylated aspartic acid ! methylated aspartic acid

2.1682. MOD:01682 monomethylated L-cysteine

Table 1684. Term [MOD:01682]
id	MOD:01682
name	monomethylated L-cysteine
def	"A protein modification that effectively replaces one hydrogen atom of an L-cysteine residue with one methyl group." [OMSSA:73, UniMod:34#C]
subset	PSI-MOD-slim
synonym	"Me1Cys" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"methylc" EXACT OMSSA-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 4 H 7 N 1 O 1 S 1"
xref	MassAvg: "117.17"
xref	MassMono: "117.024835"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00660 methylated cysteine ! methylated cysteine

2.1683. MOD:01683 monomethylated L-lysine

Table 1685. Term [MOD:01683]
id	MOD:01683
name	monomethylated L-lysine
def	"A protein modification that effectively replaces one hydrogen atom of an L-lysine residue with one methyl group." [OMSSA:0]
subset	PSI-MOD-slim
synonym	"Me1Lys" EXACT PSI-MOD-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methylation" RELATED UniMod-description []
synonym	"methylk" EXACT OMSSA-label []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 7 H 15 N 2 O 2"
xref	MassAvg: "159.21"
xref	MassMono: "159.113353"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00599 monomethylated residue ! monomethylated residue
is_a	MOD:00663 methylated lysine ! methylated lysine

2.1684. MOD:01684 palmitoylated-L-cysteine

Table 1686. Term [MOD:01684]
id	MOD:01684
name	palmitoylated-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to a palmitoylated-L-cysteine, such as N-palmitoyl-L-cysteine or S-palmitoyl-L-cysteine." [OMSSA:92, UniMod:47]
subset	PSI-MOD-slim
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
synonym	"palmitoylationc" EXACT OMSSA-label []
synonym	"PamCys" EXACT PSI-MOD-label []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "C 19 H 35 N 1 O 2 S 1"
xref	MassAvg: "341.55"
xref	MassMono: "341.238850"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00440 palmitoylated residue ! palmitoylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1685. MOD:01685 alpha-amino palmitoylated residue

Table 1687. Term [MOD:01685]
id	MOD:01685
name	alpha-amino palmitoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino group with a alpha-palmitoylamino group." [UniMod:47#N-term]
subset	PSI-MOD-slim
synonym	"N2PamRes" EXACT PSI-MOD-label []
synonym	"Palmitoyl" RELATED PSI-MS-label []
synonym	"Palmitoylation" RELATED UniMod-description []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00651 N-palmitoylated residue ! N-palmitoylated residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1686. MOD:01686 alpha-amino dimethylated residue

Table 1688. Term [MOD:01686]
id	MOD:01686
name	alpha-amino dimethylated residue
def	"A protein modification that effectively replaces two alpha amino hydrogen atoms with two methyl group." [OMSSA:38, UniMod:36#N-term]
comment	For alpha-amino acids, both N-alpha-monomethylation and complete N-alpha protonation and trimethylation have been observed, but incomplete dimethylation has not been reported as a natural process. For N-terminal proline residues, dimethylation can only be effectively accomplished with a protonated imino group, whereas this process accounts only for dimethylation and not protonation. See MOD:00889.
synonym	"di-Methylation" RELATED UniMod-description []
synonym	"Dimethyl" RELATED PSI-MS-label []
synonym	"N2Me2Res" EXACT PSI-MOD-label []
synonym	"ntermpepdimethyl" EXACT OMSSA-label []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4"
xref	DiffMono: "28.031300"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "N-term"
is_a	MOD:00429 dimethylated residue ! dimethylated residue
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1687. MOD:01687 alpha-amino trimethylated residue

Table 1689. Term [MOD:01687]
id	MOD:01687
name	alpha-amino trimethylated residue
def	"A protein modification that effectively replaces an alpha-aminium group with a trimethylaminium group." [OMSSA:12, UniMod:37#N-term]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N2Me3+Res process (MOD:01698) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N2Me3Res" EXACT PSI-MOD-label []
synonym	"ntermtrimethyl" EXACT OMSSA-label []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00430 trimethylated residue ! trimethylated residue
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue
relationship	derives_from MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.1688. MOD:01688 3-hydroxy-L-asparagine

Table 1690. Term [MOD:01688]
id	MOD:01688
name	3-hydroxy-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to one of the diastereomeric 3-hydroxy-L-asparagine residues." [OMSSA:61, UniMod:35#N]
subset	PSI-MOD-slim
synonym	"3HyAsn" EXACT PSI-MOD-label []
synonym	"hydroxylationn" EXACT OMSSA-label []
synonym	"monohydroxylated asparagine" EXACT PSI-MOD-alternate []
synonym	"Oxidation" RELATED PSI-MS-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 6 N 2 O 3"
xref	MassAvg: "130.10"
xref	MassMono: "130.037842"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue

2.1689. MOD:01689 alpha-carboxyl methylated residue

Table 1691. Term [MOD:01689]
id	MOD:01689
name	alpha-carboxyl methylated residue
def	"A protein modification that effectively converts a carboxyl-terminal residue to an alpha-carboxyl (1-carboxyl) methyl ester." [OMSSA:18, OMSSA:68, UniMod:34#C-term]
subset	PSI-MOD-slim
synonym	"C1OMeRes" EXACT PSI-MOD-label []
synonym	"ctermpepmeester" EXACT OMSSA-label []
synonym	"ctermpepmethyl" EXACT OMSSA-label []
synonym	"Methyl" RELATED PSI-MS-label []
synonym	"Methyl" RELATED UniMod-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0 S 0"
xref	DiffMono: "14.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00393 O-methylated residue ! O-methylated residue

2.1690. MOD:01690 N-[(12R)-12-hydroxymyristoyl]-L-cysteine

Table 1692. Term [MOD:01690]
id	MOD:01690
name	N-[(12R)-12-hydroxymyristoyl]-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-[(12R)-12-hydroxymyristoyl]-L-cysteine." [RESID:AA0516]
synonym	"2-[(12R)-12-hydroxytetradecanoyl]amino-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"LIPID N-[(12R)-12-hydroxymyristoyl]cysteine" EXACT UniProt-feature []
synonym	"N-[(12R)-12-hydroxymyristoyl]-L-cysteine" EXACT RESID-name []
synonym	"N-[(12R)-12-hydroxytetradecanoyl]cysteine" EXACT RESID-alternate []
xref	DiffAvg: "226.36"
xref	DiffFormula: "C 14 H 26 N 0 O 2 S 0"
xref	DiffMono: "226.193280"
xref	Formula: "C 17 H 32 N 1 O 3 S 1"
xref	MassAvg: "330.51"
xref	MassMono: "330.210290"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1691. MOD:01691 N-(12-ketomyristoyl)-L-cysteine

Table 1693. Term [MOD:01691]
id	MOD:01691
name	N-(12-ketomyristoyl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to N-(12-ketomyristoyl)-L-cysteine." [PubMed:19053188, RESID:AA0517]
synonym	"2-(12-oxotetradecanoyl)amino-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"LIPID N-(12-oxomyristoyl)cysteine" EXACT UniProt-feature []
synonym	"N-(12-ketomyristoyl)-L-cysteine" EXACT RESID-name []
synonym	"N-(12-oxotetradecanoyl)cysteine" EXACT RESID-alternate []
xref	DiffAvg: "224.34"
xref	DiffFormula: "C 14 H 24 N 0 O 2 S 0"
xref	DiffMono: "224.177630"
xref	Formula: "C 17 H 30 N 1 O 3 S 1"
xref	MassAvg: "328.49"
xref	MassMono: "328.194640"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1692. MOD:01692 glutamyl semialdehyde (Glu)

Table 1694. Term [MOD:01692]
id	MOD:01692
name	glutamyl semialdehyde (Glu)
def	"A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl semialdehyde." [PubMed:18688235, PubMed:743268]
synonym	"Deoxy" RELATED PSI-MS-label []
synonym	"gamma-glutamyl semialdehyde" EXACT PSI-MOD-alternate []
synonym	"glutamyl 5-semialdehyde" EXACT PSI-MOD-alternate []
synonym	"glutamyl aldehyde" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "C 0 H 0 N 0 O -1"
xref	DiffMono: "-15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01161 deoxygenated residue ! deoxygenated residue
is_a	MOD:01440 glutamyl semialdehyde ! glutamyl semialdehyde

2.1693. MOD:01693 alpha-amino pyridylacetylated residue

Table 1695. Term [MOD:01693]
id	MOD:01693
name	alpha-amino pyridylacetylated residue
def	"A protein modification that effectively replaces a residue alpha amino or imino hydrogen with a (pyrid-3-yl)acetyl group." [OMSSA:107, PubMed:9276974, UniMod:25#N-term]
comment	Produced by reaction with N-[(pyrid-3-yl)acetyl]oxy-succinimide [JSG].
synonym	"ntermpeppyridyl" EXACT OMSSA-label []
synonym	"Pyridylacetyl" RELATED PSI-MS-label []
synonym	"pyridylacetyl" RELATED UniMod-description []
xref	DiffAvg: "119.12"
xref	DiffFormula: "C 7 H 5 N 1 O 1"
xref	DiffMono: "119.037114"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00418 pyridylacetylated residue ! pyridylacetylated residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1694. MOD:01694 S-(coelenterazin-3a-yl)-L-cysteine

Table 1696. Term [MOD:01694]
id	MOD:01694
name	S-(coelenterazin-3a-yl)-L-cysteine
def	"A protein modification that effectively results from forming an adduct between an L-cysteine residue and the bioluminescent compound didehydrocoelenterazine to form S-(coelenterazin-3a-yl)-L-cysteine." [ChEBI:2311, PubMed:18997450, RESID:AA0526]
synonym	"(2R)-2-amino-3-([(4-hydroxyphenyl)(8-benzyl-3-oxo-6-[4-hydroxyphenyl]-3,7-dihydroimidazo[1,2-a]pyrazin-2-yl)methyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"dehydrocoelenterazine cysteine adduct" EXACT RESID-alternate []
synonym	"MOD_RES S-(coelenterazin-3a-yl)cysteine" EXACT UniProt-feature []
synonym	"S-(coelenterazin-3a-yl)-L-cysteine" EXACT RESID-name []
synonym	"symplectin chromophore" EXACT RESID-alternate []
xref	DiffAvg: "421.46"
xref	DiffFormula: "C 26 H 19 N 3 O 3 S 0"
xref	DiffMono: "421.142641"
xref	Formula: "C 29 H 24 N 4 O 4 S 1"
xref	MassAvg: "524.60"
xref	MassMono: "524.151826"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1695. MOD:01695 alpha-amino 3-(carboxamidomethylthio)propanoylated residue

Table 1697. Term [MOD:01695]
id	MOD:01695
name	alpha-amino 3-(carboxamidomethylthio)propanoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an 3-(carboxamidomethylthio)propanoyl group." [PubMed:15121203, UniMod:293#N-term]
synonym	"3-(carbamidomethylthio)propanoyl" RELATED UniMod-description []
synonym	"CAMthiopropanoyl" RELATED PSI-MS-label []
xref	DiffAvg: "145.18"
xref	DiffFormula: "C 5 H 7 N 1 O 2 S 1"
xref	DiffMono: "145.019749"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00612 3-(carboxamidomethylthio)propanoylated residue ! 3-(carboxamidomethylthio)propanoylated residue
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue

2.1696. MOD:01696 alpha-amino acylated residue

Table 1698. Term [MOD:01696]
id	MOD:01696
name	alpha-amino acylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.1697. MOD:01697 alpha-amino 4-(2-aminoethyl)benzenesulfonylated residue

Table 1699. Term [MOD:01697]
id	MOD:01697
name	alpha-amino 4-(2-aminoethyl)benzenesulfonylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an 4-(2-aminoethyl)benzenesulfonyl group." [DeltaMass:235, PubMed:8597590, UniMod:276#N-term]
comment	See the comment for MOD:00596 [JSG].
synonym	"AEBS" RELATED PSI-MS-label []
synonym	"Aminoethylbenzenesulfonylation" RELATED UniMod-description []
xref	DiffAvg: "183.23"
xref	DiffFormula: "C 8 H 9 N 1 O 2 S 1"
xref	DiffMono: "183.035400"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00596 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue ! 4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue

2.1698. MOD:01698 alpha-amino trimethylated protonated-residue

Table 1700. Term [MOD:01698]
id	MOD:01698
name	alpha-amino trimethylated protonated-residue
def	"A protein modification that effectively replaces an amino group with a trimethylaminium group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"N2Me3+Res" EXACT PSI-MOD-label []
synonym	"tri-Methylation" RELATED UniMod-description []
synonym	"Trimethyl" RELATED PSI-MS-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0 S 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00711 trimethylated protonated-residue ! trimethylated protonated-residue
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1699. MOD:01699 protonated residue

Table 1701. Term [MOD:01699]
id	MOD:01699
name	protonated residue
def	"A protein modification that effectively adds a hydrogen cation, a proton, forming a cationic residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"H+NRes" EXACT PSI-MOD-label []
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1700. MOD:01700 alpha-amino protonated residue

Table 1702. Term [MOD:01700]
id	MOD:01700
name	alpha-amino protonated residue
def	"A protein modification that effectively adds a proton to a residue alpha-amnino or alpha-imino group forming an alpha-aminium or alpha-iminium group, respectively." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"N2H+NRes" EXACT PSI-MOD-label []
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01699 protonated residue ! protonated residue

2.1701. MOD:01701 deprotonated residue

Table 1703. Term [MOD:01701]
id	MOD:01701
name	deprotonated residue
def	"A protein modification that effectively removes a hydrogen cation, a proton, forming an anionic residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"H-NRes" EXACT PSI-MOD-label []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007276"
xref	FormalCharge: "1-"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01156 protein modification categorized by chemical process ! protein modification categorized by chemical process

2.1702. MOD:01702 alpha-carboxyl deprotonated residue

Table 1704. Term [MOD:01702]
id	MOD:01702
name	alpha-carboxyl deprotonated residue
def	"A protein modification that effectively removes a proton from a residue 1-carboxyl group (referred to as the alpha-carboxyl), forming a carboxylate anion." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"C1H-NRes" EXACT PSI-MOD-label []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0"
xref	DiffMono: "-1.007276"
xref	FormalCharge: "1-"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01701 deprotonated residue ! deprotonated residue

2.1703. MOD:01703 dehydrobutyrine

Table 1705. Term [MOD:01703]
id	MOD:01703
name	dehydrobutyrine
def	"A protein modification that effectively converts a source amino acid residue to dehydrobutyrine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"beta-elim-t" EXACT OMSSA-label []
synonym	"Dehydrated" RELATED PSI-MS-label []
synonym	"Dehydrated" RELATED UniMod-interim []
synonym	"Dehydration" RELATED UniMod-description []
synonym	"dehydro" EXACT OMSSA-label []
synonym	"Dehydroamino butyric acid" EXACT DeltaMass-label []
synonym	"dHAbu" EXACT PSI-MOD-label []
synonym	"phospholosst" EXACT OMSSA-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1704. MOD:01704 dehydrobutyrine (Met)

Table 1706. Term [MOD:01704]
id	MOD:01704
name	dehydrobutyrine (Met)
def	"A protein modification that effectively converts an L-methionine residue to dehydrobutyrine, by neutral loss of methyl sulfide." [PubMed:18688235]
comment	It is expected that this neutral loss will produce a mix of (E)- and (Z)-isomers [JSG].
subset	PSI-MOD-slim
synonym	"dHAbu(Met)" EXACT PSI-MOD-label []
xref	DiffAvg: "-48.10"
xref	DiffFormula: "C -1 H -4 N 0 O 0 S -1"
xref	DiffMono: "-48.003371"
xref	Formula: "C 4 H 5 N 1 O 1"
xref	MassAvg: "83.09"
xref	MassMono: "83.037114"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01703 dehydrobutyrine ! dehydrobutyrine

2.1705. MOD:01705 isotope tagged reagent acylated residue

Table 1707. Term [MOD:01705]
id	MOD:01705
name	isotope tagged reagent acylated residue
def	"A protein modification that effectively replaces a residue hydrogen with an isotope tagged reagent acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1706. MOD:01706 isotope tagged reagent N-acylated residue

Table 1708. Term [MOD:01706]
id	MOD:01706
name	isotope tagged reagent N-acylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an isotope tagged reagent acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00670 N-acylated residue ! N-acylated residue

2.1707. MOD:01707 isotope tagged reagent O-acylated residue

Table 1709. Term [MOD:01707]
id	MOD:01707
name	isotope tagged reagent O-acylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with an isotope tagged reagent acyloxy group." [PubMed:18688235]
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00671 O-acylated residue ! O-acylated residue

2.1708. MOD:01708 isotope tagged reagent alpha-amino acylated residue

Table 1710. Term [MOD:01708]
id	MOD:01708
name	isotope tagged reagent alpha-amino acylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an isotope tagged reagent acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01696 alpha-amino acylated residue ! alpha-amino acylated residue
is_a	MOD:01705 isotope tagged reagent acylated residue ! isotope tagged reagent acylated residue
is_a	MOD:01706 isotope tagged reagent N-acylated residue ! isotope tagged reagent N-acylated residue

2.1709. MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue

Table 1711. Term [MOD:01709]
id	MOD:01709
name	iTRAQ4plex reporter+balance reagent N-acylated residue
def	"A protein modification that effectively replaces a residue amino- or imino-hydrogen with one of the Applied Biosystems iTRAQ4plex reagent reporter+balance groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01706 isotope tagged reagent N-acylated residue ! isotope tagged reagent N-acylated residue

2.1710. MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue

Table 1712. Term [MOD:01710]
id	MOD:01710
name	iTRAQ8plex reporter+balance reagent N-acylated residue
def	"A protein modification that effectively replaces a residue amino- or imino-hydrogen with one of the Applied Biosystems iTRAQ8plex reagent reporter+balance groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01706 isotope tagged reagent N-acylated residue ! isotope tagged reagent N-acylated residue

2.1711. MOD:01711 iTRAQ4plex reporter+balance reagent acylated N-terminal

Table 1713. Term [MOD:01711]
id	MOD:01711
name	iTRAQ4plex reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with one of the Applied Biosystems iTRAQ4plex reagent reporter+balance groups." [UniMod:214#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01708 isotope tagged reagent alpha-amino acylated residue ! isotope tagged reagent alpha-amino acylated residue
is_a	MOD:01709 iTRAQ4plex reporter+balance reagent N-acylated residue ! iTRAQ4plex reporter+balance reagent N-acylated residue

2.1712. MOD:01712 iTRAQ8plex reporter+balance reagent acylated N-terminal

Table 1714. Term [MOD:01712]
id	MOD:01712
name	iTRAQ8plex reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with one of the Applied Biosystems iTRAQ8plex reagent reporter+balance groups." [UniMod:214#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01708 isotope tagged reagent alpha-amino acylated residue ! isotope tagged reagent alpha-amino acylated residue
is_a	MOD:01710 iTRAQ8plex reporter+balance reagent N-acylated residue ! iTRAQ8plex reporter+balance reagent N-acylated residue

2.1713. MOD:01713 iTRAQ4plex reporter+balance reagent O-acylated residue

Table 1715. Term [MOD:01713]
id	MOD:01713
name	iTRAQ4plex reporter+balance reagent O-acylated residue
def	"A protein modification that effectively replaces a residue hydroxyl with one of the Applied Biosystems iTRAQ4plex reagent reporter+balance acyloxy groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01707 isotope tagged reagent O-acylated residue ! isotope tagged reagent O-acylated residue

2.1714. MOD:01714 iTRAQ8plex reporter+balance reagent O-acylated residue

Table 1716. Term [MOD:01714]
id	MOD:01714
name	iTRAQ8plex reporter+balance reagent O-acylated residue
def	"A protein modification that effectively replaces a residue hydroxyl with one of the Applied Biosystems iTRAQ8plex reagent reporter+balance acyloxy groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01707 isotope tagged reagent O-acylated residue ! isotope tagged reagent O-acylated residue

2.1715. MOD:01715 TMT6plex reporter+balance reagent acylated residue

Table 1717. Term [MOD:01715]
id	MOD:01715
name	TMT6plex reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with a Proteome Sciences TMT6plex reporter+balance group." [UniMod:214]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01705 isotope tagged reagent acylated residue ! isotope tagged reagent acylated residue

2.1716. MOD:01716 TMT6plex reporter fragment

Table 1718. Term [MOD:01716]
id	MOD:01716
name	TMT6plex reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-126 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex reporter fragment" EXACT PSI-MOD-alternate []
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment
relationship	derives_from MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue
relationship	derives_from MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1717. MOD:01717 TMT6plex reporter+balance reagent N-acylated residue

Table 1719. Term [MOD:01717]
id	MOD:01717
name	TMT6plex reporter+balance reagent N-acylated residue
def	"A protein modification that effectively replaces a residue amino- or imino-hydrogen with a Proteome Sciences TMT6plex reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01706 isotope tagged reagent N-acylated residue ! isotope tagged reagent N-acylated residue

2.1718. MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal

Table 1720. Term [MOD:01718]
id	MOD:01718
name	TMT6plex reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a Proteome Sciences TMT6plex reporter+balance group." [UniMod:214#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01708 isotope tagged reagent alpha-amino acylated residue ! isotope tagged reagent alpha-amino acylated residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue

2.1719. MOD:01719 TMT6plex reporter+balance reagent O-acylated residue

Table 1721. Term [MOD:01719]
id	MOD:01719
name	TMT6plex reporter+balance reagent O-acylated residue
def	"A protein modification that effectively replaces a residue hydroxyl with one of the Proteome Sciences TMT6plex reagent reporter+balance acyloxy groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01707 isotope tagged reagent O-acylated residue ! isotope tagged reagent O-acylated residue

2.1720. MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue

Table 1722. Term [MOD:01720]
id	MOD:01720
name	TMT6plex-126 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue

2.1721. MOD:01721 TMT6plex-126 reporter+balance reagent acylated N-terminal

Table 1723. Term [MOD:01721]
id	MOD:01721
name	TMT6plex-126 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-126 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue

2.1722. MOD:01722 TMT6plex-126 reporter+balance reagent N6-acylated lysine

Table 1724. Term [MOD:01722]
id	MOD:01722
name	TMT6plex-126 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1723. MOD:01723 TMT6plex-126 reporter+balance reagent O4'-acylated tyrosine

Table 1725. Term [MOD:01723]
id	MOD:01723
name	TMT6plex-126 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 17 (13)C 4 H 29 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "392.23"
xref	MassMono: "392.226261"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue

2.1724. MOD:01724 TMT6plex-126 reporter+balance reagent N'-acylated histidine

Table 1726. Term [MOD:01724]
id	MOD:01724
name	TMT6plex-126 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue

2.1725. MOD:01725 TMT6plex-126 reporter+balance reagent O3-acylated serine

Table 1727. Term [MOD:01725]
id	MOD:01725
name	TMT6plex-126 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue

2.1726. MOD:01726 TMT6plex-126 reporter+balance reagent O3-acylated threonine

Table 1728. Term [MOD:01726]
id	MOD:01726
name	TMT6plex-126 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-126 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue

2.1727. MOD:01727 TMT6plex-126 reporter fragment

Table 1729. Term [MOD:01727]
id	MOD:01727
name	TMT6plex-126 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-126 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-126 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 8 H 16 (14)N 1"
xref	MassAvg: "126.13"
xref	MassMono: "126.127726"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01720 TMT6plex-126 reporter+balance reagent acylated residue ! TMT6plex-126 reporter+balance reagent acylated residue
relationship	derives_from MOD:01822 cysTMT6plex-zero reporter+balance reagent cysteine disulfide ! cysTMT6plex-zero reporter+balance reagent cysteine disulfide
relationship	derives_from MOD:01823 cysTMT6plex-126 reporter+balance reagent cysteine disulfide ! cysTMT6plex-126 reporter+balance reagent cysteine disulfide

2.1728. MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue

Table 1730. Term [MOD:01728]
id	MOD:01728
name	TMT6plex-127 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue

2.1729. MOD:01729 TMT6plex-127 reporter+balance reagent acylated N-terminal

Table 1731. Term [MOD:01729]
id	MOD:01729
name	TMT6plex-127 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-127 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue

2.1730. MOD:01730 TMT6plex-127 reporter+balance reagent N6-acylated lysine

Table 1732. Term [MOD:01730]
id	MOD:01730
name	TMT6plex-127 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1731. MOD:01731 TMT6plex-127 reporter+balance reagent O4'-acylated tyrosine

Table 1733. Term [MOD:01731]
id	MOD:01731
name	TMT6plex-127 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	MassAvg: "229.16"
xref	MassMono: "229.162932"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue

2.1732. MOD:01732 TMT6plex-127 reporter+balance reagent N'-acylated histidine

Table 1734. Term [MOD:01732]
id	MOD:01732
name	TMT6plex-127 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue

2.1733. MOD:01733 TMT6plex-127 reporter+balance reagent O3-acylated serine

Table 1735. Term [MOD:01733]
id	MOD:01733
name	TMT6plex-127 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue

2.1734. MOD:01734 TMT6plex-127 reporter+balance reagent O3-acylated threonine

Table 1736. Term [MOD:01734]
id	MOD:01734
name	TMT6plex-127 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-127 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue

2.1735. MOD:01735 TMT6plex-127 reporter fragment

Table 1737. Term [MOD:01735]
id	MOD:01735
name	TMT6plex-127 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-127 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-127 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 7 (13)C 1 H 16 (14)N 1"
xref	MassAvg: "127.13"
xref	MassMono: "127.131081"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01728 TMT6plex-127 reporter+balance reagent acylated residue ! TMT6plex-127 reporter+balance reagent acylated residue
relationship	derives_from MOD:01824 cysTMT6plex-127 reporter+balance reagent cysteine disulfide ! cysTMT6plex-127 reporter+balance reagent cysteine disulfide

2.1736. MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue

Table 1738. Term [MOD:01736]
id	MOD:01736
name	TMT6plex-128 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue

2.1737. MOD:01737 TMT6plex-128 reporter+balance reagent acylated N-terminal

Table 1739. Term [MOD:01737]
id	MOD:01737
name	TMT6plex-128 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-128 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue

2.1738. MOD:01738 TMT6plex-128 reporter+balance reagent N6-acylated lysine

Table 1740. Term [MOD:01738]
id	MOD:01738
name	TMT6plex-128 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1739. MOD:01739 TMT6plex-128 reporter+balance reagent O4'-acylated tyrosine

Table 1741. Term [MOD:01739]
id	MOD:01739
name	TMT6plex-128 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 17 (13)C 4 H 29 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "392.23"
xref	MassMono: "392.226261"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue

2.1740. MOD:01740 TMT6plex-128 reporter+balance reagent N'-acylated histidine

Table 1742. Term [MOD:01740]
id	MOD:01740
name	TMT6plex-128 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue

2.1741. MOD:01741 TMT6plex-128 reporter+balance reagent O3-acylated serine

Table 1743. Term [MOD:01741]
id	MOD:01741
name	TMT6plex-128 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue

2.1742. MOD:01742 TMT6plex-128 reporter+balance reagent O3-acylated threonine

Table 1744. Term [MOD:01742]
id	MOD:01742
name	TMT6plex-128 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-128 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue

2.1743. MOD:01743 TMT6plex-128 reporter fragment

Table 1745. Term [MOD:01743]
id	MOD:01743
name	TMT6plex-128 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-128 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-128 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 6 (13)C 2 H 16 (14)N 1"
xref	MassAvg: "128.13"
xref	MassMono: "128.134436"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01736 TMT6plex-128 reporter+balance reagent acylated residue ! TMT6plex-128 reporter+balance reagent acylated residue
relationship	derives_from MOD:01825 cysTMT6plex-128 reporter+balance reagent cysteine disulfide ! cysTMT6plex-128 reporter+balance reagent cysteine disulfide

2.1744. MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue

Table 1746. Term [MOD:01744]
id	MOD:01744
name	TMT6plex-129 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue

2.1745. MOD:01745 TMT6plex-129 reporter+balance reagent acylated N-terminal

Table 1747. Term [MOD:01745]
id	MOD:01745
name	TMT6plex-129 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-129 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue

2.1746. MOD:01746 TMT6plex-129 reporter+balance reagent N6-acylated lysine

Table 1748. Term [MOD:01746]
id	MOD:01746
name	TMT6plex-129 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1747. MOD:01747 TMT6plex-129 reporter+balance reagent O4'-acylated tyrosine

Table 1749. Term [MOD:01747]
id	MOD:01747
name	TMT6plex-129 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 17 (13)C 4 H 29 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "392.23"
xref	MassMono: "392.226261"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue

2.1748. MOD:01748 TMT6plex-129 reporter+balance reagent N'-acylated histidine

Table 1750. Term [MOD:01748]
id	MOD:01748
name	TMT6plex-129 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue

2.1749. MOD:01749 TMT6plex-129 reporter+balance reagent O3-acylated serine

Table 1751. Term [MOD:01749]
id	MOD:01749
name	TMT6plex-129 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue

2.1750. MOD:01750 TMT6plex-129 reporter+balance reagent O3-acylated threonine

Table 1752. Term [MOD:01750]
id	MOD:01750
name	TMT6plex-129 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-129 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue

2.1751. MOD:01751 TMT6plex-129 reporter fragment

Table 1753. Term [MOD:01751]
id	MOD:01751
name	TMT6plex-129 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-129 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-129 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 5 (13)C 3 H 16 (14)N 1"
xref	MassAvg: "129.14"
xref	MassMono: "129.137790"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01744 TMT6plex-129 reporter+balance reagent acylated residue ! TMT6plex-129 reporter+balance reagent acylated residue
relationship	derives_from MOD:01826 cysTMT6plex-129 reporter+balance reagent cysteine disulfide ! cysTMT6plex-129 reporter+balance reagent cysteine disulfide

2.1752. MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue

Table 1754. Term [MOD:01752]
id	MOD:01752
name	TMT6plex-130 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue
relationship	derives_from MOD:01827 cysTMT6plex-130 reporter+balance reagent cysteine disulfide ! cysTMT6plex-130 reporter+balance reagent cysteine disulfide

2.1753. MOD:01753 TMT6plex-130 reporter+balance reagent acylated N-terminal

Table 1755. Term [MOD:01753]
id	MOD:01753
name	TMT6plex-130 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-130 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1754. MOD:01754 TMT6plex-130 reporter+balance reagent N6-acylated lysine

Table 1756. Term [MOD:01754]
id	MOD:01754
name	TMT6plex-130 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1755. MOD:01755 TMT6plex-130 reporter+balance reagent O4'-acylated tyrosine

Table 1757. Term [MOD:01755]
id	MOD:01755
name	TMT6plex-130 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 17 (13)C 4 H 29 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "392.23"
xref	MassMono: "392.226261"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1756. MOD:01756 TMT6plex-130 reporter+balance reagent N'-acylated histidine

Table 1758. Term [MOD:01756]
id	MOD:01756
name	TMT6plex-130 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1757. MOD:01757 TMT6plex-130 reporter+balance reagent O3-acylated serine

Table 1759. Term [MOD:01757]
id	MOD:01757
name	TMT6plex-130 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1758. MOD:01758 TMT6plex-130 reporter+balance reagent O3-acylated threonine

Table 1760. Term [MOD:01758]
id	MOD:01758
name	TMT6plex-130 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-130 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1759. MOD:01759 TMT6plex-130 reporter fragment

Table 1761. Term [MOD:01759]
id	MOD:01759
name	TMT6plex-130 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-130 reagent acylated residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-130 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 4 (13)C 4 H 16 (14)N 1"
xref	MassAvg: "130.14"
xref	MassMono: "130.141145"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01752 TMT6plex-130 reporter+balance reagent acylated residue ! TMT6plex-130 reporter+balance reagent acylated residue

2.1760. MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue

Table 1762. Term [MOD:01760]
id	MOD:01760
name	TMT6plex-131 reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [UniMod:737]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"cysTMT6plex-131 reporter fragment" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01715 TMT6plex reporter+balance reagent acylated residue ! TMT6plex reporter+balance reagent acylated residue
relationship	derives_from MOD:01828 cysTMT6plex-131 reporter+balance reagent cysteine disulfide ! cysTMT6plex-131 reporter+balance reagent cysteine disulfide

2.1761. MOD:01761 TMT6plex-131 reporter+balance reagent acylated N-terminal

Table 1763. Term [MOD:01761]
id	MOD:01761
name	TMT6plex-131 reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Proteome Sciences TMT6plex-131 reporter+balance group." [UniMod:737#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01718 TMT6plex reporter+balance reagent acylated N-terminal ! TMT6plex reporter+balance reagent acylated N-terminal
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1762. MOD:01762 TMT6plex-131 reporter+balance reagent N6-acylated lysine

Table 1764. Term [MOD:01762]
id	MOD:01762
name	TMT6plex-131 reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6'-hydrogen atom of a lysine residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [UniMod:737#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 32 (14)N 3 (15)N 1 O 3"
xref	MassAvg: "357.26"
xref	MassMono: "357.257895"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1763. MOD:01763 TMT6plex-131 reporter+balance reagent O4'-acylated tyrosine

Table 1765. Term [MOD:01763]
id	MOD:01763
name	TMT6plex-131 reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [UniMod:737#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 17 (13)C 4 H 29 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "392.23"
xref	MassMono: "392.226261"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1764. MOD:01764 TMT6plex-131 reporter+balance reagent N'-acylated histidine

Table 1766. Term [MOD:01764]
id	MOD:01764
name	TMT6plex-131 reporter+balance reagent N'-acylated histidine
def	"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 14 (13)C 4 H 27 (14)N 4 (15)N 1 O 3"
xref	MassAvg: "366.22"
xref	MassMono: "366.221844"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01717 TMT6plex reporter+balance reagent N-acylated residue ! TMT6plex reporter+balance reagent N-acylated residue
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1765. MOD:01765 TMT6plex-131 reporter+balance reagent O3-acylated serine

Table 1767. Term [MOD:01765]
id	MOD:01765
name	TMT6plex-131 reporter+balance reagent O3-acylated serine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 11 (13)C 4 H 25 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "316.19"
xref	MassMono: "316.194961"
xref	Origin: "S"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1766. MOD:01766 TMT6plex-131 reporter+balance reagent O3-acylated threonine

Table 1768. Term [MOD:01766]
id	MOD:01766
name	TMT6plex-131 reporter+balance reagent O3-acylated threonine
def	"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-131 reporter+balance group." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "229.16"
xref	DiffFormula: "(12)C 8 (13)C 4 H 20 (14)N 1 (15)N 1 O 2"
xref	DiffMono: "229.162932"
xref	Formula: "(12)C 12 (13)C 4 H 27 (14)N 2 (15)N 1 O 4"
xref	MassAvg: "330.21"
xref	MassMono: "330.210611"
xref	Origin: "T"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01719 TMT6plex reporter+balance reagent O-acylated residue ! TMT6plex reporter+balance reagent O-acylated residue
is_a	MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1767. MOD:01767 TMT6plex-131 reporter fragment

Table 1769. Term [MOD:01767]
id	MOD:01767
name	TMT6plex-131 reporter fragment
def	"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-131 reagent acylated residue." [PubMed:18688235]
synonym	"2,6-dimethyl-1-methylidenepiperidinium" EXACT PSI-MOD-alternate []
synonym	"Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"TMT6plex" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 4 (13)C 4 H 16 (15)N 1"
xref	MassAvg: "131.14"
xref	MassMono: "131.138180"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01716 TMT6plex reporter fragment ! TMT6plex reporter fragment
relationship	derives_from MOD:01760 TMT6plex-131 reporter+balance reagent acylated residue ! TMT6plex-131 reporter+balance reagent acylated residue

2.1768. MOD:01768 O-palmitoleylated residue

Table 1770. Term [MOD:01768]
id	MOD:01768
name	O-palmitoleylated residue
def	"A protein modification that effectively replaces a residue hydroxyl group with a palmitoleyloxy group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "236.40"
xref	DiffFormula: "C 16 H 28 N 0 O 1"
xref	DiffMono: "236.214016"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00671 O-acylated residue ! O-acylated residue
is_a	MOD:01423 palmitoleylated residue ! palmitoleylated residue

2.1769. MOD:01769 O-palmitoleyl-L-threonine

Table 1771. Term [MOD:01769]
id	MOD:01769
name	O-palmitoleyl-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-palmitoleyl-L-threonine." [OMSSA:188, PubMed:6642431, PubMed:8413602, RESID:AA0079#var, UniMod:431#T]
subset	PSI-MOD-slim
synonym	"(2S,3R)-2-amino-3-((Z)-9-hexadecenoyloxy)butanoic acid" EXACT PSI-MOD-alternate []
synonym	"L-threonine cis-9-hexadecenoate ester" EXACT PSI-MOD-alternate []
synonym	"mod188" EXACT OMSSA-label []
synonym	"O-palmitoleylated L-threonine" EXACT PSI-MOD-alternate []
synonym	"O3-palmitoleyl-threonine" EXACT PSI-MOD-alternate []
synonym	"Palmitoleyl" RELATED PSI-MS-label []
synonym	"palmitoleyl" RELATED UniMod-description []
xref	DiffAvg: "236.40"
xref	DiffFormula: "C 16 H 28 N 0 O 1"
xref	DiffMono: "236.214016"
xref	Formula: "C 20 H 35 N 1 O 3"
xref	MassAvg: "337.50"
xref	MassMono: "337.261694"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01768 O-palmitoleylated residue ! O-palmitoleylated residue

2.1770. MOD:01770 O-palmitoyl-L-threonine amide

Table 1772. Term [MOD:01770]
id	MOD:01770
name	O-palmitoyl-L-threonine amide
def	"A protein modification that effectively converts an L-threonine residue to O-palmitoyl-L-threonine amide." [PubMed:8413602, RESID:AA0079#var, RESID:AA0097#var]
synonym	"(2S,3R)-2-amino-3-(hexadecanoyloxy)butanamide" EXACT PSI-MOD-alternate []
synonym	"OPamThrN" EXACT PSI-MOD-label []
xref	DiffAvg: "254.44"
xref	DiffFormula: "C 16 H 32 N 1 O 1"
xref	DiffMono: "254.248390"
xref	Formula: "C 20 H 39 N 2 O 3"
xref	MassAvg: "355.54"
xref	MassMono: "355.296068"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
relationship	has_functional_parent MOD:00088 O-palmitoyl-L-threonine ! O-palmitoyl-L-threonine
relationship	has_functional_parent MOD:00106 L-threonine amide ! L-threonine amide

2.1771. MOD:01771 farnesyl reporter fragment

Table 1773. Term [MOD:01771]
id	MOD:01771
name	farnesyl reporter fragment
def	"The farnesyl cation protein modification reporter fragment produced by fragmentation of some farnesyl modified residues." [PubMed:15609361, PubMed:18688235]
subset	PSI-MOD-slim
synonym	"(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ylium" EXACT PSI-MOD-alternate []
synonym	"Farn+" EXACT PSI-MOD-label []
synonym	"farnesyl cation" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "C 15 H 25"
xref	MassAvg: "205.36"
xref	MassMono: "205.195077"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment
relationship	derives_from MOD:00437 farnesylated residue ! farnesylated residue

2.1772. MOD:01772 palmityl reporter fragment

Table 1774. Term [MOD:01772]
id	MOD:01772
name	palmityl reporter fragment
def	"The palmityl cation protein modification reporter fragment produced by fragmentation of some palmitoyl modified residues." [PubMed:18688235, PubMed:8413602]
subset	PSI-MOD-slim
synonym	"palmityl cation" RELATED PSI-MS-label []
synonym	"Pam+" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "C 16 H 31 O 1"
xref	MassAvg: "239.42"
xref	MassMono: "239.236942"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment
relationship	derives_from MOD:00440 palmitoylated residue ! palmitoylated residue

2.1773. MOD:01773 N6,N6,N6-trimethyl-L-lysine with neutral loss of trimethylamine

Table 1775. Term [MOD:01773]
id	MOD:01773
name	N6,N6,N6-trimethyl-L-lysine with neutral loss of trimethylamine
def	"Covalent modification of a trimethyllysine residue with secondary loss of a neutral trimethylamine molecular fragment." [PubMed:17205979, PubMed:18688235]
subset	PSI-MOD-slim
synonym	"dMe3N6Me3+Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "-59.11"
xref	DiffFormula: "C -3 H -9 N -1 O 0"
xref	DiffMono: "-59.074048"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 10 N 1 O 1"
xref	MassAvg: "112.15"
xref	MassMono: "112.075690"
xref	Origin: "MOD:00083"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00431 modified residue with a secondary neutral loss ! modified residue with a secondary neutral loss
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
relationship	derives_from MOD:00083 N6,N6,N6-trimethyl-L-lysine ! N6,N6,N6-trimethyl-L-lysine

2.1774. MOD:01774 N6-octanoyl-L-lysine

Table 1776. Term [MOD:01774]
id	MOD:01774
name	N6-octanoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-octanoyl-L-lysine." [PubMed:12591875, PubMed:2215217, RESID:AA0527]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-(octanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"epsilon-octanoyllysine" EXACT RESID-alternate []
synonym	"N(zeta)-octanoyllysine" EXACT RESID-alternate []
synonym	"N6-(1-oxooctyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-octanoyl-L-lysine" EXACT RESID-name []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1"
xref	DiffMono: "126.104465"
xref	Formula: "C 14 H 26 N 2 O 2"
xref	MassAvg: "254.37"
xref	MassMono: "254.199428"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00666 octanoylated residue ! octanoylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1775. MOD:01775 5-glutamyl serotonin

Table 1777. Term [MOD:01775]
id	MOD:01775
name	5-glutamyl serotonin
def	"A protein modification that effectively converts an L-glutamine residue to 5-glutamyl serotonin." [PubMed:11805836, PubMed:14697203, RESID:AA0528]
synonym	"(2S)-2-amino-5-([2-(5-hydroxy-1H-indol-3-yl)ethyl]amino)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"5-glutamyl serotonin" EXACT RESID-name []
synonym	"N2-(gamma-glutamyl)-5-hydoxytryptamine" EXACT RESID-alternate []
synonym	"N5-[2-(5-hydroxy-3-indolyl)ethyl]glutamine" EXACT RESID-alternate []
xref	DiffAvg: "159.19"
xref	DiffFormula: "C 10 H 9 N 1 O 1"
xref	DiffMono: "159.068414"
xref	Formula: "C 15 H 17 N 3 O 3"
xref	MassAvg: "287.32"
xref	MassMono: "287.126991"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.1776. MOD:01776 S-methylthiocarbonylaminoethylcysteine (Cys)

Table 1778. Term [MOD:01776]
id	MOD:01776
name	S-methylthiocarbonylaminoethylcysteine (Cys)
def	"A protein modification that effectively converts an L-cysteine residue to S-methylthiocarbonylaminoethylcysteine." [PubMed:18688235, PubMed:20608637]
comment	This modified residue is a chemical analog of N6-acetyl-L-lysine produced from L-cysteine by methylthiocarbonylaziridine (MTCA, S-methyl aziridine-1-carbothioate).
synonym	"(2R)-2-amino-3-([2-([(methylsulfanyl)carbonyl]amino)ethyl]sulfanyl)propanoic acid" EXACT PSI-MOD-alternate []
synonym	"L-cysteine N-(methylthiocarbonyl)aziridine adduct" EXACT PSI-MOD-alternate []
synonym	"MTCTK" EXACT PSI-MOD-alternate []
synonym	"N6-methylthiocarbonyl-4-thialysine" EXACT PSI-MOD-alternate []
synonym	"S-[2-([(methylthio)carbonyl]amino)ethyl]-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "117.17"
xref	DiffFormula: "C 4 H 7 N 1 O 1 S 1"
xref	DiffMono: "117.024835"
xref	Formula: "C 7 H 12 N 2 O 2 S 2"
xref	MassAvg: "220.31"
xref	MassMono: "220.034020"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1777. MOD:01777 S-(glycyl)-L-cysteine (Gly)

Table 1779. Term [MOD:01777]
id	MOD:01777
name	S-(glycyl)-L-cysteine (Gly)
def	"A protein modification that effectively converts a C-terminal glycine residue to S-(glycyl)-L-cysteine by forming a thioester bond with a free L-cysteine." [ChEBI:22050, PubMed:17726030, PubMed:18359941, PubMed:18771296, PubMed:18799456, PubMed:18842002, PubMed:3306404, RESID:AA0206]
comment	This is not the cross-linking of two peptides, but the modification of a C-terminal glycine by formation of an thioester bond with a free cysteine. For the cross-linking of two peptide see MOD:00211 [JSG].
synonym	"(2R)-2-amino-3-[(aminoacetyl)sulfanyl]propanoic acid" EXACT RESID-systematic []
synonym	"1-(cystein-S-yl)-glycinate" EXACT RESID-alternate []
synonym	"glycine cysteine thioester" EXACT RESID-alternate []
synonym	"MOD_RES CysO-cysteine adduct" EXACT UniProt-feature []
synonym	"S-(2-amino-1-oxoethyl)cysteine" EXACT RESID-alternate []
synonym	"S-(glycyl)-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "103.14"
xref	DiffFormula: "C 3 H 5 N 1 O 1 S 1"
xref	DiffMono: "103.009185"
xref	Formula: "C 5 H 9 N 2 O 3 S 1"
xref	MassAvg: "177.20"
xref	MassMono: "177.033388"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.1778. MOD:01778 N-(glycyl)-L-cysteine

Table 1780. Term [MOD:01778]
id	MOD:01778
name	N-(glycyl)-L-cysteine
def	"A protein modification that effectively converts a C-terminal glycine residue to N-(glycyl)-L-cysteine by forming a peptide bond with a free L-cysteine." [PubMed:18771296, PubMed:18799456, PubMed:18842002, RESID:AA0529]
synonym	"(2R)-2-[(aminoacetyl)amino]-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES CysO-cysteine adduct" EXACT UniProt-feature []
synonym	"N-(2-amino-1-oxoethyl)cysteine" EXACT RESID-alternate []
synonym	"N-(glycyl)-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "103.14"
xref	DiffFormula: "C 3 H 5 N 1 O 1 S 1"
xref	DiffMono: "103.009185"
xref	Formula: "C 5 H 9 N 2 O 3 S 1"
xref	MassAvg: "177.20"
xref	MassMono: "177.033388"
xref	Origin: "G"
xref	Source: "hypothetical"
xref	TermSpec: "C-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.1779. MOD:01779 N6-(L-lysyl)-L-lysine

Table 1781. Term [MOD:01779]
id	MOD:01779
name	N6-(L-lysyl)-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-(L-lysyl)-L-lysine by formation of an isopeptide bond between the carboxyl group of a free lysine and the N6-amino group of the peptidyl L-lysine." [PubMed:18201202, PubMed:20729861, RESID:AA0530]
comment	This is not the cross-linking of two peptides, but the modification of a peptidyl lysine by formation of an isopeptide bond with a free lysine [JSG].
synonym	"(2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"N6-(alpha-lysyl)-lysine" EXACT RESID-alternate []
synonym	"N6-(L-lysyl)-L-lysine" EXACT RESID-name []
xref	DiffAvg: "128.18"
xref	DiffFormula: "C 6 H 12 N 2 O 1"
xref	DiffMono: "128.094963"
xref	Formula: "C 12 H 24 N 4 O 2"
xref	MassAvg: "256.35"
xref	MassMono: "256.189926"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1780. MOD:01780 N6-(beta-lysyl)-L-5-hydroxylysine

Table 1782. Term [MOD:01780]
id	MOD:01780
name	N6-(beta-lysyl)-L-5-hydroxylysine
def	"A protein modification that effectively converts an L-lysine residue to N6-(beta-lysyl)-L-5-hydroxylysine by formation of an isopeptide bond between the carboxyl group of a free beta-lysine and the N6-amino group of a peptidyl L-lysine." [PubMed:18201202, PubMed:20729861, RESID:AA0531]
synonym	"(2S)-2-amino-6-([(3R)-3,6-diaminohexanoyl]amino)-5-hydroxyhexanoic acid" EXACT RESID-systematic []
synonym	"5-hydroxy-N6-(beta-lysyl)-L-lysine" EXACT RESID-name []
synonym	"5-hydroxy-N6-[(3R)-beta-lysyl]lysine" EXACT RESID-alternate []
synonym	"EF-P lysine derivative" EXACT RESID-alternate []
synonym	"lysyl spermidine derivative [misidentification]" EXACT RESID-alternate []
synonym	"MOD_RES N6-(3,6-diaminohexanoyl)-5-hydroxylysine" EXACT UniProt-feature []
synonym	"N6-[(3R)-3,6-diaminohexanoyl]-L-5-hydroxylysine" EXACT RESID-alternate []
xref	DiffAvg: "144.17"
xref	DiffFormula: "C 6 H 12 N 2 O 2"
xref	DiffMono: "144.089878"
xref	Formula: "C 12 H 24 N 4 O 3"
xref	MassAvg: "272.35"
xref	MassMono: "272.184841"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1781. MOD:01781 N6-butanoyl-L-lysine

Table 1783. Term [MOD:01781]
id	MOD:01781
name	N6-butanoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-butanoyl-L-lysine." [PubMed:17267393, PubMed:20715035, RESID:AA0532, UniMod:1289]
comment	The binding of histone peptides with butanoylated lysine to nuclear bromodomain proteins is non-specific and weaker than binding to the corresponding acetylated lysine peptides [JSG].
synonym	"(2S)-2-amino-6-(butanoylamino)hexanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-azanyl-6-(butanoylamino)hexanoic acid" EXACT RESID-alternate []
synonym	"2-amino-6-butyrylaminocaproic acid" EXACT RESID-alternate []
synonym	"epsilon-butanoyl-L-lysine" EXACT RESID-alternate []
synonym	"epsilon-butyryl-L-lysine" EXACT RESID-alternate []
synonym	"N(zeta)-butanoyllysine" EXACT RESID-alternate []
synonym	"N6-(1-oxobutyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-butanoyl-L-lysine" EXACT RESID-name []
synonym	"N6-butyryllysine" EXACT RESID-alternate []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 N 0 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "C 10 H 18 N 2 O 2"
xref	MassAvg: "198.27"
xref	MassMono: "198.136828"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine
is_a	MOD:01997 N-butanoylated residue ! N-butanoylated residue

2.1782. MOD:01782 N-methyl-L-serine

Table 1784. Term [MOD:01782]
id	MOD:01782
name	N-methyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to N-methyl-L-serine." [PubMed:20668449, RESID:AA0533]
subset	PSI-MOD-slim
synonym	"(2S)-3-hydroxy-2-(methylamino)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N-methylserine" EXACT UniProt-feature []
synonym	"N-methyl-L-serine" EXACT RESID-name []
synonym	"N-methylserine" EXACT RESID-alternate []
xref	DiffAvg: "14.03"
xref	DiffFormula: "C 1 H 2 N 0 O 0"
xref	DiffMono: "14.015650"
xref	Formula: "C 4 H 7 N 1 O 2"
xref	MassAvg: "101.10"
xref	MassMono: "101.047678"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01680 alpha-amino monomethylated residue ! alpha-amino monomethylated residue
is_a	MOD:01800 N-methylated serine ! N-methylated serine

2.1783. MOD:01783 N,N-dimethyl-L-serine

Table 1785. Term [MOD:01783]
id	MOD:01783
name	N,N-dimethyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to N,N-dimethyl-L-serine." [PubMed:20668449, RESID:AA0534]
synonym	"(2S)-2-(dimethylamino)propanoic acid" EXACT RESID-systematic []
synonym	"MOD_RES N,N-dimethylserine" EXACT UniProt-feature []
synonym	"N,N-dimethyl-L-serine" EXACT RESID-name []
synonym	"N,N-dimethylserine" EXACT RESID-alternate []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 5 H 10 N 1 O 2"
xref	MassAvg: "116.14"
xref	MassMono: "116.071154"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01686 alpha-amino dimethylated residue ! alpha-amino dimethylated residue
is_a	MOD:01800 N-methylated serine ! N-methylated serine

2.1784. MOD:01784 N,N,N-trimethyl-L-serine

Table 1786. Term [MOD:01784]
id	MOD:01784
name	N,N,N-trimethyl-L-serine
def	"A protein modification that effectively converts an L-serine residue to N,N,N-trimethyl-L-serine." [PubMed:20668449, PubMed:3979397, RESID:AA0535]
subset	PSI-MOD-slim
synonym	"(1S)-1-carboxy-2-hydroxy-N,N,N-trimethylethanaminium" EXACT RESID-systematic []
synonym	"(1S)-1-carboxy-2-hydroxy-N,N,N-trimethylethanazanium" EXACT RESID-alternate []
synonym	"(2S)-2-trimethylammonio-3-hydroxypropanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N,N,N-trimethylserine" EXACT UniProt-feature []
synonym	"N,N,N-trimethyl-L-serine" EXACT RESID-name []
synonym	"N,N,N-trimethylserine cation" EXACT RESID-alternate []
synonym	"N,N,N-trimethylserinium" EXACT RESID-alternate []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0"
xref	DiffMono: "43.054227"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 13 N 1 O 2"
xref	MassAvg: "131.17"
xref	MassMono: "131.094080"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01698 alpha-amino trimethylated protonated-residue ! alpha-amino trimethylated protonated-residue
is_a	MOD:01800 N-methylated serine ! N-methylated serine

2.1785. MOD:01785 O-(L-isoglutamyl)-L-threonine (active site intermediate)

Table 1787. Term [MOD:01785]
id	MOD:01785
name	O-(L-isoglutamyl)-L-threonine (active site intermediate)
def	"A protein modification that effectively converts an L-threonine residue to O-(L-isoglutamyl)-L-threonine, using free L-glutamine and releasing ammonia." [PubMed:8706862, RESID:AA0536#THR]
comment	This is not an ester cross-link of peptides [JSG].
synonym	"(2S)-2-amino-5-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-4-amino-4-carboxybutanoyl]oxy)-propanoic acid" EXACT RESID-alternate []
synonym	"5-(threon-O3-yl)glutamate" EXACT RESID-alternate []
synonym	"O(beta)-(gamma-glutamyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)threonine" EXACT RESID-alternate []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 9 H 14 N 2 O 5"
xref	MassAvg: "230.22"
xref	MassMono: "230.090272"
xref	Origin: "T"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00671 O-acylated residue ! O-acylated residue
is_a	MOD:01979 O-(L-isoglutamyl)-L-threonine ! O-(L-isoglutamyl)-L-threonine

2.1786. MOD:01786 3'-nitro-L-tyrosine

Table 1788. Term [MOD:01786]
id	MOD:01786
name	3'-nitro-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to 3'-nitro-L-tyrosine." [ChEBI:44454, PubMed:16944230, PubMed:5339594, RESID:AA0537]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid" EXACT RESID-systematic []
synonym	"3'-nitro-L-tyrosine" EXACT RESID-name []
synonym	"3-nitro-L-tyrosine" EXACT RESID-alternate []
synonym	"3-nitrotyrosine" EXACT RESID-alternate []
synonym	"m-nitrotyrosine" EXACT RESID-alternate []
synonym	"meta-nitrotyrosine" EXACT RESID-alternate []
synonym	"MOD_RES 3'-Nitrotyrosine" EXACT UniProt-feature []
xref	DiffAvg: "45.00"
xref	DiffFormula: "C 0 H -1 N 1 O 2"
xref	DiffMono: "44.985078"
xref	Formula: "C 9 H 8 N 2 O 4"
xref	MassAvg: "208.17"
xref	MassMono: "208.048407"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01352 nitrated L-tyrosine ! nitrated L-tyrosine

2.1787. MOD:01787 5'-(L-tyros-5'-yl)amino-L-tyrosine

Table 1789. Term [MOD:01787]
id	MOD:01787
name	5'-(L-tyros-5'-yl)amino-L-tyrosine
def	"A protein modification that effectively cross-links two L-tyrosine residues through their 5' positions by amine nitrogen to form 5'-(L-tyros-5'-yl)amino-L-tyrosine." [PubMed:18781570, RESID:AA0459]
comment	Cross-link 2.
synonym	"(2S,2’S)-3,3'-[iminobis(4-hydroxybenzene-3,1-diyl)]bis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"5'-(L-tyros-5'-yl)amino-L-tyrosine" EXACT RESID-name []
synonym	"5'-[(tyros-5'-yl)amino]tyrosine" EXACT RESID-alternate []
synonym	"5'-tyrosyl-5'-aminotyrosine" EXACT RESID-alternate []
synonym	"bis(LTQ) linkage" EXACT RESID-alternate []
synonym	"CROSSLNK 5'-tyrosyl-5'-aminotyrosine (Tyr-Tyr) (interchain)" EXACT UniProt-feature []
xref	DiffAvg: "13.00"
xref	DiffFormula: "C 0 H -1 N 1 O 0"
xref	DiffMono: "12.995249"
xref	Formula: "C 18 H 17 N 3 O 4"
xref	MassAvg: "339.35"
xref	MassMono: "339.121906"
xref	Origin: "Y, Y"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1788. MOD:01788 histidine immonium ion

Table 1790. Term [MOD:01788]
id	MOD:01788
name	histidine immonium ion
def	"A protein modification that effectively converts an N-terminal L-histidine residue to histidine immonium ion." [PubMed:17074506, PubMed:18688235]
comment	This fragment corresponds to the first ion in an a+ series.
subset	PSI-MOD-slim
synonym	"2-(1H-imidazolyl)ethaniminium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 8 N 3 O 0"
xref	MassAvg: "110.14"
xref	MassMono: "110.071274"
xref	Origin: "H"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01527 residue reporter fragment ! residue reporter fragment

2.1789. MOD:01789 phenylalanine immonium ion

Table 1791. Term [MOD:01789]
id	MOD:01789
name	phenylalanine immonium ion
def	"A protein modification that effectively converts an N-terminal L-phenylalanine residue to phenylalanine immonium ion." [PubMed:17074506, PubMed:18688235]
comment	This fragment corresponds to the first ion in an a+ series.
subset	PSI-MOD-slim
synonym	"2-phenylethaniminium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 10 N 1 O 0"
xref	MassAvg: "120.17"
xref	MassMono: "120.080776"
xref	Origin: "F"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01527 residue reporter fragment ! residue reporter fragment

2.1790. MOD:01790 tyrosine immonium ion

Table 1792. Term [MOD:01790]
id	MOD:01790
name	tyrosine immonium ion
def	"A protein modification that effectively converts an an N-terminal L-tyrosine residue to tyrosine immonium ion." [PubMed:17074506, PubMed:18688235]
comment	This fragment corresponds to the first ion in an a+ series.
subset	PSI-MOD-slim
synonym	"2-(4-hydroxyphenyl)ethaniminium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 10 N 1 O 1"
xref	MassAvg: "136.17"
xref	MassMono: "136.075690"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01527 residue reporter fragment ! residue reporter fragment

2.1791. MOD:01791 phosphohistidine immonium ion

Table 1793. Term [MOD:01791]
id	MOD:01791
name	phosphohistidine immonium ion
def	"A protein modification that effectively converts an N-terminal phosphohistidine residue to phosphohistidine immonium ion." [PubMed:17690871, PubMed:18688235, PubMed:20847263]
comment	This fragment corresponds to the first ion in an a+ series.
subset	PSI-MOD-slim
synonym	"2-(1H-imidazolyl)ethaniminium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 3 O 3 P 1"
xref	MassAvg: "190.12"
xref	MassMono: "190.037604"
xref	Origin: "MOD:00890"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01527 residue reporter fragment ! residue reporter fragment
relationship	derives_from MOD:00890 phosphorylated L-histidine ! phosphorylated L-histidine

2.1792. MOD:01792 phosphotyrosine immonium ion

Table 1794. Term [MOD:01792]
id	MOD:01792
name	phosphotyrosine immonium ion
def	"A protein modification that effectively converts an N-terminal O4'-phospho-L-tyrosine residue to tyrosine immonium ion." [PubMed:17690871, PubMed:18688235]
comment	This fragment corresponds to the first ion in an a+ series.
subset	PSI-MOD-slim
synonym	"2-(4-phosphonoxyphenyl)ethaniminium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 8 H 11 N 1 O 4 P 1"
xref	MassAvg: "216.15"
xref	MassMono: "216.042021"
xref	Origin: "MOD:00048"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01527 residue reporter fragment ! residue reporter fragment
relationship	derives_from MOD:00048 O4'-phospho-L-tyrosine ! O4'-phospho-L-tyrosine

2.1793. MOD:01793 S-carboxamidomethyl-L-cysteine sulfoxide

Table 1795. Term [MOD:01793]
id	MOD:01793
name	S-carboxamidomethyl-L-cysteine sulfoxide
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxamidomethyl-L-cysteine sulfoxide." [PubMed:11212008, PubMed:17689096, PubMed:18306178, PubMed:18688235]
synonym	"CamCO" EXACT PSI-MOD-alternate []
synonym	"S-carbamoylmethyl-L-cysteine sulfoxide" EXACT PSI-MOD-alternate []
xref	DiffAvg: "73.05"
xref	DiffFormula: "C 2 H 3 N 1 O 2"
xref	DiffMono: "73.016378"
xref	Formula: "C 5 H 8 N 2 O 3 S 1"
xref	MassAvg: "176.19"
xref	MassMono: "176.025563"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01854 sulfur monooxygenated residue ! sulfur monooxygenated residue
relationship	derives_from MOD:01060 S-carboxamidomethyl-L-cysteine ! S-carboxamidomethyl-L-cysteine

2.1794. MOD:01794 1x(13)C,3x(2)H labeled monomethylated residue

Table 1796. Term [MOD:01794]
id	MOD:01794
name	1x(13)C,3x(2)H labeled monomethylated residue
def	"A protein modification that effectively replaces the methyl group of a residue containing common isotopes with a 1x(13)C,3x(2)H labeled monomethylated residue." [PubMed:18688235]
synonym	"Methyl:2H(3)13C(1)" RELATED PSI-MS-label []
xref	DiffAvg: "18.04"
xref	DiffFormula: "(13)C 1 (1)H -1 (2)H 3"
xref	DiffMono: "18.037835"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue

2.1795. MOD:01795 1x(13)C,3x(2)H C(6)-labeled L-methionine

Table 1797. Term [MOD:01795]
id	MOD:01795
name	1x(13)C,3x(2)H C(6)-labeled L-methionine
def	"A protein modification that effectively converts an L-methionine residue containing common isotopes to 1x(13)C,3x(2)H C(6)-labeled L-methionine." [PubMed:15782174, PubMed:18688235]
synonym	"Methyl:2H(3)13C(1)" RELATED PSI-MS-label []
xref	DiffAvg: "4.02"
xref	DiffFormula: "(12)C -1 (13)C 1 (1)H -3 (2)H 3"
xref	DiffMono: "4.022185"
xref	Formula: "(12)C 4 (13)C 1 (1)H 6 (2)H 3 N 1 O 1 S 1"
xref	MassAvg: "135.06"
xref	MassMono: "135.062670"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01794 1x(13)C,3x(2)H labeled monomethylated residue ! 1x(13)C,3x(2)H labeled monomethylated residue

2.1796. MOD:01796 1x(13)C,3x(2)H C(6)-labeled L-methionine sulfoxide

Table 1798. Term [MOD:01796]
id	MOD:01796
name	1x(13)C,3x(2)H C(6)-labeled L-methionine sulfoxide
def	"A protein modification that effectively converts an L-methionine residue containing common isotopes to 1x(13)C,3x(2)H C(6)-labeled L-methionine sulfoxide." [PubMed:15782174, PubMed:18688235]
xref	DiffAvg: "20.02"
xref	DiffFormula: "(12)C -1 (13)C 1 (1)H -3 (2)H 3 O 1"
xref	DiffMono: "20.017100"
xref	Formula: "(12)C 4 (13)C 1 (1)H 6 (2)H 3 N 1 O 2 S 1"
xref	MassAvg: "151.06"
xref	MassMono: "151.057585"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00839 (2)H deuterium labeled residue ! (2)H deuterium labeled residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01794 1x(13)C,3x(2)H labeled monomethylated residue ! 1x(13)C,3x(2)H labeled monomethylated residue

2.1797. MOD:01797 1'-phosphohistidine immonium ion

Table 1799. Term [MOD:01797]
id	MOD:01797
name	1'-phosphohistidine immonium ion
def	"A protein modification that effectively converts an N-terminal 1'-phosphohistidine residue to 1'-phosphohistidine immonium ion." [PubMed:17690871, PubMed:18688235, PubMed:20847263]
comment	This fragment corresponds to the first ion in an a+ series.
synonym	"2-((1-phosphono-1H-imidazol-4-yl)ethaniminium" EXACT PSI-MOD-alternate []
synonym	"Ntau-phosphorylated L-histidine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 3 O 3 P 1"
xref	MassAvg: "190.12"
xref	MassMono: "190.037604"
xref	Origin: "MOD:00044"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01791 phosphohistidine immonium ion ! phosphohistidine immonium ion
relationship	derives_from MOD:00044 1'-phospho-L-histidine ! 1'-phospho-L-histidine

2.1798. MOD:01798 3'-phosphohistidine immonium ion

Table 1800. Term [MOD:01798]
id	MOD:01798
name	3'-phosphohistidine immonium ion
def	"A protein modification that effectively converts an N-terminal 3'-phosphohistidine residue to 3'-phosphohistidine immonium ion." [PubMed:18688235]
comment	This fragment corresponds to the first ion in an a+ series.
synonym	"2-(1-phosphono-1H-imidazol-5-yl)ethaniminium" EXACT PSI-MOD-alternate []
synonym	"Npi-phosphorylated L-histidine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-27.00"
xref	DiffFormula: "C -1 H 1 N 0 O -1"
xref	DiffMono: "-26.987638"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 3 O 3 P 1"
xref	MassAvg: "190.12"
xref	MassMono: "190.037604"
xref	Origin: "MOD:00045"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01791 phosphohistidine immonium ion ! phosphohistidine immonium ion
relationship	derives_from MOD:00045 3'-phospho-L-histidine ! 3'-phospho-L-histidine

2.1799. MOD:01799 methylated serine

Table 1801. Term [MOD:01799]
id	MOD:01799
name	methylated serine
def	"A protein modification that effectively converts an L-alanine residue to a methylated serine, such as N-methylserine, N,N-dimethylserine, or N,N,N-trimethylserine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeSer" EXACT PSI-MOD-label []
xref	Origin: "S"
is_a	MOD:00427 methylated residue ! methylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1800. MOD:01800 N-methylated serine

Table 1802. Term [MOD:01800]
id	MOD:01800
name	N-methylated serine
def	"A protein modification that effectively replaces an L-serine alpha amino hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue
is_a	MOD:01799 methylated serine ! methylated serine

2.1801. MOD:01801 protonated L-serine (L-serinium) residue

Table 1803. Term [MOD:01801]
id	MOD:01801
name	protonated L-serine (L-serinium) residue
def	"A protein modification that effectively converts an L-serine residue to an L-serinium (protonated L-serine)." [PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 3 H 7 N 1 O 2"
xref	MassAvg: "89.09"
xref	MassMono: "89.047130"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.1802. MOD:01802 N,N,N-trimethyl-L-serine (from L-serinium)

Table 1804. Term [MOD:01802]
id	MOD:01802
name	N,N,N-trimethyl-L-serine (from L-serinium)
def	"A protein modification that effectively converts an L-serinium (protonated L-serine) residue to an N,N,N-trimethyl-L-serine." [PubMed:18688235]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N2Me3+Ser process (MOD:00071) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N2Me3Ala" EXACT PSI-MOD-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 13 N 1 O 2"
xref	MassAvg: "131.17"
xref	MassMono: "131.094080"
xref	Origin: "MOD:01801"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01687 alpha-amino trimethylated residue ! alpha-amino trimethylated residue
relationship	derives_from MOD:01801 protonated L-serine (L-serinium) residue ! protonated L-serine (L-serinium) residue

2.1803. MOD:01803 O-methylated threonine

Table 1805. Term [MOD:01803]
id	MOD:01803
name	O-methylated threonine
def	"A protein modification that effectively converts an L-threonine residue to a methylated threonine, such as O-methyl-L-threonine or L-threonine methyl ester." [PubMed:18688235]
synonym	"OMeThr" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00393 O-methylated residue ! O-methylated residue
is_a	MOD:01418 methylated threonine ! methylated threonine

2.1804. MOD:01804 glycosylphosphorylated residue

Table 1806. Term [MOD:01804]
id	MOD:01804
name	glycosylphosphorylated residue
def	"A protein modification that effectively results from forming an adduct with a glycosylphosphate through a phosphodiester bond." [PubMed:18688235]
is_a	MOD:00764 glycoconjugated residue ! glycoconjugated residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.1805. MOD:01805 N-(L-isoaspartyl)-glycine (Asp)

Table 1807. Term [MOD:01805]
id	MOD:01805
name	N-(L-isoaspartyl)-glycine (Asp)
def	"A protein modification that effectively crosslinks an L-aspartic acid residue and a glycine residue by an isopeptide bond with formation of N-(L-isoaspartyl)-glycine and the release of water." [ChEBI:21479, PubMed:1826288, PubMed:18671394, RESID:AA0126]
comment	Cross-link 2.
synonym	"(2S)-2-amino-4-(carboxymethyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N4-(carboxymethyl)-butanediamic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl glycine isopeptide (Asp-Gly)" EXACT UniProt-feature []
synonym	"CROSSLNK Isoaspartyl glycine isopeptide (Gly-Asp)" EXACT UniProt-feature []
synonym	"isoaspartyl glycine" EXACT RESID-alternate []
synonym	"N-(L-isoaspartyl)-glycine" EXACT RESID-name []
synonym	"N-beta-aspartylglycine" EXACT RESID-alternate []
synonym	"N4-(carboxymethyl)-asparagine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 7 N 2 O 3"
xref	MassAvg: "155.13"
xref	MassMono: "155.045667"
xref	Origin: "D, G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01928 N-(L-isoaspartyl)-glycine ! N-(L-isoaspartyl)-glycine

2.1806. MOD:01806 N,N-dimethyl-L-leucine

Table 1808. Term [MOD:01806]
id	MOD:01806
name	N,N-dimethyl-L-leucine
def	"A protein modification that effectively converts an L-leucine residue to N,N-dimethyl-L-leucine." [PubMed:19522542, RESID:AA0538]
synonym	"(2S)-2-(dimethylamino)-4-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-(dimethylamino)-4-methylvaleric acid" EXACT RESID-alternate []
synonym	"2-(dimethylazanyl)-4-methylpentanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N,N-dimethylleucine" EXACT UniProt-feature []
synonym	"N,N-dimethyl-L-leucine" EXACT RESID-name []
synonym	"N,N-dimethylleucine" EXACT RESID-alternate []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 16 N 1 O 1"
xref	MassAvg: "142.22"
xref	MassMono: "142.123189"
xref	Origin: "L"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:01686 alpha-amino dimethylated residue ! alpha-amino dimethylated residue
is_a	MOD:01808 N-methylated leucine ! N-methylated leucine

2.1807. MOD:01807 N-formyl-L-glutamic acid

Table 1809. Term [MOD:01807]
id	MOD:01807
name	N-formyl-L-glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to N-formyl-L-glutamic acid." [PubMed:18001127, RESID:AA0539]
synonym	"(2S)-2-(formylamino)pentanedioic acid" EXACT RESID-systematic []
synonym	"2-(formylazanyl)pentanedioic acid" EXACT RESID-alternate []
synonym	"2-formamidopentanedioic acid" EXACT RESID-alternate []
synonym	"2-formylaminopentanedioic acid" EXACT RESID-alternate []
synonym	"N-formyl-L-glutamic acid" EXACT RESID-name []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 6 H 8 N 1 O 4"
xref	MassAvg: "158.13"
xref	MassMono: "158.045333"
xref	Origin: "E"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1808. MOD:01808 N-methylated leucine

Table 1810. Term [MOD:01808]
id	MOD:01808
name	N-methylated leucine
def	"A protein modification that effectively replaces an L-leucine alpha amino hydrogen with a methyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"MeLeu" EXACT PSI-MOD-label []
xref	Origin: "L"
is_a	MOD:00662 methylated leucine ! methylated leucine
is_a	MOD:01460 alpha-amino methylated residue ! alpha-amino methylated residue

2.1809. MOD:01809 5x(13)C,1x(15)N labeled residue

Table 1811. Term [MOD:01809]
id	MOD:01809
name	5x(13)C,1x(15)N labeled residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 5x(13)C,1x(15)N labeled residue." [PubMed:12771378, UniMod:268]
synonym	"13C(5) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "6.01"
xref	DiffFormula: "(12)C -5 (13)C 5 (14)N -1 (15)N 1"
xref	DiffMono: "6.013809"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue
is_a	MOD:00843 (15)N labeled residue ! (15)N labeled residue

2.1810. MOD:01810 5x(13)C,1x(15)N labeled L-proline

Table 1812. Term [MOD:01810]
id	MOD:01810
name	5x(13)C,1x(15)N labeled L-proline
def	"A protein modification that effectively converts an L-proline residue to 5x(13)C,1x(15)N labeled L-proline." [PubMed:12771378, UniMod:268#P]
synonym	"13C(5) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "6.01"
xref	DiffFormula: "(12)C -5 (13)C 5 (14)N -1 (15)N 1"
xref	DiffMono: "6.013809"
xref	Formula: "(13)C 5 H 7 (15)N 1 O 1"
xref	MassAvg: "103.07"
xref	MassMono: "103.066573"
xref	Origin: "P"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01809 5x(13)C,1x(15)N labeled residue ! 5x(13)C,1x(15)N labeled residue

2.1811. MOD:01811 5x(13)C,1x(15)N labeled L-methionine

Table 1813. Term [MOD:01811]
id	MOD:01811
name	5x(13)C,1x(15)N labeled L-methionine
def	"A protein modification that effectively converts an L-methionine residue to 5x(13)C,1x(15)N labeled L-methionine." [PubMed:12771378, UniMod:268#M]
synonym	"13C(5) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "6.01"
xref	DiffFormula: "(12)C -5 (13)C 5 (14)N -1 (15)N 1"
xref	DiffMono: "6.013809"
xref	Formula: "(13)C 5 H 9 (15)N 1 O 1 S 1"
xref	MassAvg: "137.05"
xref	MassMono: "137.054294"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01809 5x(13)C,1x(15)N labeled residue ! 5x(13)C,1x(15)N labeled residue

2.1812. MOD:01812 5x(13)C,1x(15)N labeled L-methionine sulfoxide

Table 1814. Term [MOD:01812]
id	MOD:01812
name	5x(13)C,1x(15)N labeled L-methionine sulfoxide
def	"A protein modification that effectively converts an L-methionine residue to 5x(13)C,1x(15)N labeled L-methionine sulfoxide." [PubMed:12771378, UniMod:268#M]
synonym	"13C(5) 15N(1) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)15N(1)" RELATED PSI-MS-label []
xref	DiffAvg: "6.01"
xref	DiffFormula: "(12)C -5 (13)C 5 (14)N -1 (15)N 1"
xref	DiffMono: "6.013809"
xref	Formula: "(13)C 5 H 9 (15)N 1 O 2 S 1"
xref	MassAvg: "153.05"
xref	MassMono: "153.049209"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00719 L-methionine sulfoxide ! L-methionine sulfoxide
is_a	MOD:01809 5x(13)C,1x(15)N labeled residue ! 5x(13)C,1x(15)N labeled residue

2.1813. MOD:01813 morpholine-2-acetylated residue

Table 1815. Term [MOD:01813]
id	MOD:01813
name	morpholine-2-acetylated residue
def	"A protein modification that effectively substitutes a morpholine-2-acetyl group for a hydrogen atom." [PubMed:10446193, UniMod:29]
comment	The UniMod name "N-Succinimidyl-3-morpholine acetate" appears to have been a typographical error [JSG].
synonym	"N-Succinimidyl-2-morpholine acetate" RELATED UniMod-description []
synonym	"N-succinimidylmorpholine-2-acetate derivative" EXACT PSI-MOD-alternate []
synonym	"SMA" RELATED PSI-MS-label []
xref	DiffAvg: "127.14"
xref	DiffFormula: "C 6 H 9 N 1 O 2"
xref	DiffMono: "127.063329"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
is_a	MOD:00649 acylated residue ! acylated residue
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1814. MOD:01814 L-cysteine 3-hydroxy-2,5-pyridinedicarboxylic acid

Table 1816. Term [MOD:01814]
id	MOD:01814
name	L-cysteine 3-hydroxy-2,5-pyridinedicarboxylic acid
def	"A protein modification that effectively cross-links a cysteine and two serine residues to form L-cysteine 3-hydroxy-2,5-pyridinedicarboxylic acid." [PubMed:18406324, PubMed:19678698, PubMed:893891, RESID:AA0540]
comment	Cross-link 3.
synonym	"6-[(1R)-1-amino-2-sulfanylethyl]-3-hydroxypyridine-2,5-dicarboxylic acid" EXACT RESID-systematic []
synonym	"6-[1-azanyl-2-sulfanylethyl]-3-hydroxypyridine-2,5-dicarboxylic acid" EXACT RESID-alternate []
synonym	"L-cysteine 3-hydroxy-2,5-pyridinedicarboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-54.07"
xref	DiffFormula: "C 0 H -8 N -1 O -2 S 0"
xref	DiffMono: "-54.055504"
xref	Formula: "C 9 H 7 N 2 O 3 S 1"
xref	MassAvg: "223.23"
xref	MassMono: "223.017738"
xref	Origin: "C, S, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01425 pyridinyl ring crosslinked residues ! pyridinyl ring crosslinked residues

2.1815. MOD:01815 L-glutamate thiazole-4-carboxylic acid

Table 1817. Term [MOD:01815]
id	MOD:01815
name	L-glutamate thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-glutamic acid residue to form L-glutamate thiazole-4-carboxylic acid." [PubMed:18406324, PubMed:19678698, PubMed:893891, RESID:AA0541]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-3-carboxypropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[-1-azanyl-3-carboxypropyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Glu-Cys)" EXACT UniProt-feature []
synonym	"L-glutamate thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 8 H 8 N 2 O 3 S 1"
xref	MassAvg: "212.22"
xref	MassMono: "212.025563"
xref	Origin: "C, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1816. MOD:01816 2'-hydroxy-L-tryptophan

Table 1818. Term [MOD:01816]
id	MOD:01816
name	2'-hydroxy-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to a 2'-hydroxy-L-tryptophan." [PubMed:11714714, RESID:AA0542]
synonym	"(2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"2'-hydroxy-L-tryptophan" EXACT RESID-name []
synonym	"2-azanyl-3-(2-hydroxy-1H-indol-3-yl)propanoic acid" EXACT RESID-alternate []
synonym	"2-hydroxy-L-tryptophan" EXACT RESID-alternate []
synonym	"2-hydroxy-tryptophan" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 11 H 10 N 2 O 2"
xref	MassAvg: "202.21"
xref	MassMono: "202.074228"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01622 monohydroxylated tryptophan ! monohydroxylated tryptophan

2.1817. MOD:01817 oxidation of tryptophan to 2'-oxo-L-tryptophan

Table 1819. Term [MOD:01817]
id	MOD:01817
name	oxidation of tryptophan to 2'-oxo-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to a 2'-oxo-L-tryptophan." [PubMed:9461080, RESID:AA0543]
synonym	"(2S)-2-amino-3-[(3S)-2-oxo-2,3-dihydro-1H-indol-3-yl]propanoic acid" EXACT RESID-systematic []
synonym	"2'-oxo-L-tryptophan" EXACT RESID-name []
synonym	"2-azanyl-3-[(3S)-2-oxo-2,3-dihydro-1H-indol-3-yl]propanoic acid" EXACT RESID-alternate []
synonym	"2-oxo-L-tryptophan" EXACT RESID-alternate []
synonym	"2-oxotryptophan" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 11 H 10 N 2 O 2"
xref	MassAvg: "202.21"
xref	MassMono: "202.074228"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1818. MOD:01818 1'-(L-tryptophan-3'-yl)-L-tryptophan

Table 1820. Term [MOD:01818]
id	MOD:01818
name	1'-(L-tryptophan-3'-yl)-L-tryptophan
def	"A protein modification that effectively cross-links two tryptophan residues to form 1'-(L-tryptophan-3'-yl)-L-tryptophan." [PubMed:20600836, RESID:AA0544]
comment	Cross-link 2.
synonym	"(2S,2’S)-3,3'-(3’H-1,3'-biindole-3,3'-diyl)bis(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"1-(L-tryptophan-3-yl)-L-tryptophan" EXACT RESID-name []
synonym	"2-amino-3-[2-[2-amino-3-(2-carboxyethyl)-1H-indol-4-yl]-1H-indol-3-yl]propanoic acid" EXACT RESID-alternate []
synonym	"3-[(2S)-2-amino-2-carboxyethyl]-3-(3-[(2S)-2-amino-2-carboxyethyl]-1H-indol-2-yl)-1H-indole" EXACT RESID-systematic []
synonym	"3-[2-azanyl-2-carboxyethyl]-3-(3-[2-azanyl-2-carboxyethyl]-1H-indol-2-yl)-1H-indole" EXACT RESID-alternate []
synonym	"ditryptophan" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 22 H 18 N 4 O 2"
xref	MassAvg: "370.41"
xref	MassMono: "370.142976"
xref	Origin: "W, W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00918 modified L-tryptophan residue ! modified L-tryptophan residue

2.1819. MOD:01819 N6-succinyl-L-lysine

Table 1821. Term [MOD:01819]
id	MOD:01819
name	N6-succinyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-succinyl-L-lysine." [PubMed:16582421, PubMed:21151122, RESID:AA0545]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-6-[(3-carboxypropanoyl)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-[(3-carboxypropanoyl)azanyl]hexanoic acid" EXACT RESID-alternate []
synonym	"4-[[(5S)-5-amino-6-hydroxy-6-oxohexyl]amino]-4-oxobutanoate" EXACT RESID-alternate []
synonym	"MOD_RES N6-succinyllysine" EXACT UniProt-feature []
synonym	"N(epsilon)-(succinyl)lysine" EXACT RESID-alternate []
synonym	"N6-succinyl-L-lysine" EXACT RESID-name []
synonym	"succinyllysine" EXACT RESID-alternate []
xref	DiffAvg: "100.07"
xref	DiffFormula: "C 4 H 4 N 0 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "C 10 H 16 N 2 O 4"
xref	MassAvg: "228.25"
xref	MassMono: "228.111007"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01029 succinylated residue ! succinylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1820. MOD:01820 isotope tagged sufhydryl reagent modified cysteine

Table 1822. Term [MOD:01820]
id	MOD:01820
name	isotope tagged sufhydryl reagent modified cysteine
def	"A protein modification that effectively replaces a cysteine sulhydryl hydrogen with an isotope tagged sulfhydryl reagent group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1821. MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide

Table 1823. Term [MOD:01821]
id	MOD:01821
name	cysTMT6plex reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex reporter+balance group." [UniMod:985, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01429 (15)N isotope tagged reagent ! (15)N isotope tagged reagent
is_a	MOD:01820 isotope tagged sufhydryl reagent modified cysteine ! isotope tagged sufhydryl reagent modified cysteine

2.1822. MOD:01822 cysTMT6plex-zero reporter+balance reagent cysteine disulfide

Table 1824. Term [MOD:01822]
id	MOD:01822
name	cysTMT6plex-zero reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-zero reporter+balance group." [UniMod:984, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysTMT" RELATED UniMod-interim []
synonym	"Native cysteine-reactive Tandem Mass Tag™" RELATED UniMod-description []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "299.17"
xref	DiffFormula: "(12)C 14 H 25 (14)N 3 O 2 S 1"
xref	DiffMono: "299.166748"
xref	Formula: "(12)C 17 H 32 (14)N 4 O 4 S 2"
xref	MassAvg: "420.19"
xref	MassMono: "420.186498"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1823. MOD:01823 cysTMT6plex-126 reporter+balance reagent cysteine disulfide

Table 1825. Term [MOD:01823]
id	MOD:01823
name	cysTMT6plex-126 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-126 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1824. MOD:01824 cysTMT6plex-127 reporter+balance reagent cysteine disulfide

Table 1826. Term [MOD:01824]
id	MOD:01824
name	cysTMT6plex-127 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-127 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1825. MOD:01825 cysTMT6plex-128 reporter+balance reagent cysteine disulfide

Table 1827. Term [MOD:01825]
id	MOD:01825
name	cysTMT6plex-128 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-128 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1826. MOD:01826 cysTMT6plex-129 reporter+balance reagent cysteine disulfide

Table 1828. Term [MOD:01826]
id	MOD:01826
name	cysTMT6plex-129 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-129 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1827. MOD:01827 cysTMT6plex-130 reporter+balance reagent cysteine disulfide

Table 1829. Term [MOD:01827]
id	MOD:01827
name	cysTMT6plex-130 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-130 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1828. MOD:01828 cysTMT6plex-131 reporter+balance reagent cysteine disulfide

Table 1830. Term [MOD:01828]
id	MOD:01828
name	cysTMT6plex-131 reporter+balance reagent cysteine disulfide
def	"A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-131 reporter+balance group." [PubMed:18688235, URL:http\://www.piercenet.com/files/2162220.pdf]
comment	The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"cysteine-reactive Sixplex Tandem Mass Tag™" RELATED UniMod-description []
synonym	"cysTMT6plex" RELATED UniMod-interim []
synonym	"S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl" EXACT PSI-MOD-alternate []
xref	DiffAvg: "304.18"
xref	DiffFormula: "(12)C 10 (13)C 4 H 25 (14)N 2 (15)N 1 O 2 S 1"
xref	DiffMono: "304.177202"
xref	Formula: "(12)C 13 (13)C 4 H 32 (14)N 3 (15)N 1 O 4 S 2"
xref	MassAvg: "425.20"
xref	MassMono: "425.196952"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01821 cysTMT6plex reporter+balance reagent cysteine disulfide ! cysTMT6plex reporter+balance reagent cysteine disulfide

2.1829. MOD:01829 S-carboxymethyl-L-cysteine sulfoxide

Table 1831. Term [MOD:01829]
id	MOD:01829
name	S-carboxymethyl-L-cysteine sulfoxide
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxymethyl-L-cysteine sulfoxide." [PubMed:17689096, PubMed:18688235]
synonym	"CmCO" EXACT PSI-MOD-alternate []
xref	DiffAvg: "58.04"
xref	DiffFormula: "C 2 H 2 N 0 O 2 S 0"
xref	DiffMono: "58.005479"
xref	Formula: "C 5 H 7 N 1 O 3 S 1"
xref	MassAvg: "161.18"
xref	MassMono: "161.014664"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01854 sulfur monooxygenated residue ! sulfur monooxygenated residue
relationship	derives_from MOD:01061 S-carboxymethyl-L-cysteine ! S-carboxymethyl-L-cysteine

2.1830. MOD:01830 S-carboxymethyl-L-cysteine sulfone

Table 1832. Term [MOD:01830]
id	MOD:01830
name	S-carboxymethyl-L-cysteine sulfone
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxymethyl-L-cysteine sulfone." [PubMed:18688235]
synonym	"CmCO2" EXACT PSI-MOD-label []
xref	DiffAvg: "74.03"
xref	DiffFormula: "C 2 H 2 N 0 O 3 S 0"
xref	DiffMono: "74.000394"
xref	Formula: "C 5 H 7 N 1 O 4 S 1"
xref	MassAvg: "177.17"
xref	MassMono: "177.009579"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01855 sulfur dioxygenated residue ! sulfur dioxygenated residue
relationship	derives_from MOD:01061 S-carboxymethyl-L-cysteine ! S-carboxymethyl-L-cysteine

2.1831. MOD:01831 S-carboxamidomethyl-L-cysteine sulfone

Table 1833. Term [MOD:01831]
id	MOD:01831
name	S-carboxamidomethyl-L-cysteine sulfone
def	"A protein modification that effectively converts an L-cysteine residue to S-carboxamidomethyl-L-cysteine sulfone." [PubMed:18688235]
synonym	"CamCO2" EXACT PSI-MOD-label []
synonym	"S-carbamoylmethyl-L-cysteine sulfone" EXACT PSI-MOD-alternate []
xref	DiffAvg: "89.05"
xref	DiffFormula: "C 2 H 3 N 1 O 3"
xref	DiffMono: "89.011293"
xref	Formula: "C 5 H 8 N 2 O 4 S 1"
xref	MassAvg: "192.19"
xref	MassMono: "192.020478"
xref	Origin: "C"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:01855 sulfur dioxygenated residue ! sulfur dioxygenated residue
relationship	derives_from MOD:01060 S-carboxamidomethyl-L-cysteine ! S-carboxamidomethyl-L-cysteine

2.1832. MOD:01832 5x(13)C-labeled residue

Table 1834. Term [MOD:01832]
id	MOD:01832
name	5x(13)C-labeled residue
def	"A protein modification that effectively converts a residue containing common isotopes to a 5x(13)C-labeled residue." [PubMed:12771378, UniMod:772]
synonym	"13C(5) Silac label" RELATED UniMod-description []
synonym	"Label:13C(5)" RELATED PSI-MS-label []
xref	DiffAvg: "5.02"
xref	DiffFormula: "(12)C -5 (13)C 5"
xref	DiffMono: "5.016774"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00842 (13)C labeled residue ! (13)C labeled residue

2.1833. MOD:01833 5x(13)C-labeled L-methionine

Table 1835. Term [MOD:01833]
id	MOD:01833
name	5x(13)C-labeled L-methionine
def	"A protein modification that effectively converts an L-methionine residue containing common isotopes to 5x(13)C-labeled L-methionine." [PubMed:18688235, url:]
xref	DiffAvg: "5.02"
xref	DiffFormula: "(12)C -5 (13)C 5 H 0 N 0 O 0 S 0"
xref	DiffMono: "5.016774"
xref	Formula: "(13)C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "136.06"
xref	MassMono: "136.057259"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01832 5x(13)C-labeled residue ! 5x(13)C-labeled residue

2.1834. MOD:01834 5x(13)C-labeled L-methionine sulfoxide

Table 1836. Term [MOD:01834]
id	MOD:01834
name	5x(13)C-labeled L-methionine sulfoxide
def	"A protein modification that effectively converts an L-methionine residue containing common isotopes to 5x(13)C-labeled L-methionine sulfoxide." [PubMed:18688235]
xref	DiffAvg: "21.01"
xref	DiffFormula: "(12)C -5 (13)C 5 H 0 N 0 O 1 S 0"
xref	DiffMono: "21.011689"
xref	Formula: "(13)C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "152.05"
xref	MassMono: "152.052174"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00719 L-methionine sulfoxide ! L-methionine sulfoxide
is_a	MOD:01832 5x(13)C-labeled residue ! 5x(13)C-labeled residue

2.1835. MOD:01835 5x(13)C-labeled L-methionine sulfone

Table 1837. Term [MOD:01835]
id	MOD:01835
name	5x(13)C-labeled L-methionine sulfone
def	"A protein modification that effectively converts an L-methionine residue containing common isotopes to 5x(13)C-labeled L-methionine sulfone." [PubMed:18688235]
xref	DiffAvg: "37.01"
xref	DiffFormula: "(12)C -5 (13)C 5 H 0 N 0 O 2 S 0"
xref	DiffMono: "37.006603"
xref	Formula: "(13)C 5 H 9 N 1 O 3 S 1"
xref	MassAvg: "168.05"
xref	MassMono: "168.047088"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00256 L-methionine sulfone ! L-methionine sulfone
is_a	MOD:01832 5x(13)C-labeled residue ! 5x(13)C-labeled residue

2.1836. MOD:01836 N6-[([1-(6-nitro-2H-1,3-benzodioxol-5-yl)ethoxy]carbonyl]lysine

Table 1838. Term [MOD:01836]
id	MOD:01836
name	N6-[([1-(6-nitro-2H-1,3-benzodioxol-5-yl)ethoxy]carbonyl]lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-[([1-(6-nitro-2H-1,3-benzodioxol-5-yl)ethoxy]carbonyl]lysine." [PubMed:18688235, PubMed:20218600, PubMed:21271704]
synonym	"(2S)-2-amino-6-[([1-(6-nitro-1,3-benzodioxol-5-yl)ethoxy]carbonyl)amino]hexanoic acid" EXACT PSI-MOD-alternate []
synonym	"[(alpha-methyl-6-nitro-piperonyloxy)carbonyl]lysine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "237.17"
xref	DiffFormula: "C 10 H 7 N 1 O 6"
xref	DiffMono: "237.027337"
xref	Formula: "C 16 H 19 N 3 O 7"
xref	MassAvg: "365.34"
xref	MassMono: "365.122300"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1837. MOD:01837 L-lanthionine (Cys-Cys)

Table 1839. Term [MOD:01837]
id	MOD:01837
name	L-lanthionine (Cys-Cys)
def	"A protein modification that effectively cross-links two L-cysteine residues with a thioether bond to form L-lanthionine." [ChEBI:21347, PubMed:20805503, PubMed:6007887, RESID:AA0110#CYS2]
comment	Cross-link 2.
synonym	"(2R,2’R)-3,3'-sulfanediylbis(2-aminopropanoic acid)" EXACT RESID-systematic []
synonym	"®-S-(2-amino-2-carboxyethyl)-L-cysteine" EXACT RESID-alternate []
synonym	"(R,R)-2,6-diamino-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(R,R)-3,3'-thiobis-(2-aminopropanoic acid)" EXACT RESID-alternate []
synonym	"(R,R)-bis(2-amino-2-carboxyethyl)sulfide" EXACT RESID-alternate []
synonym	"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid" EXACT RESID-alternate []
synonym	"3,3'-thiobis-L-alanine" EXACT RESID-alternate []
synonym	"L-lanthionine" EXACT RESID-name []
xref	DiffAvg: "-34.08"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S -1"
xref	DiffMono: "-33.987721"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01839 L-lanthionine ! L-lanthionine

2.1838. MOD:01838 L-lysinoalanine (Lys)

Table 1840. Term [MOD:01838]
id	MOD:01838
name	L-lysinoalanine (Lys)
def	"A protein modification that effectively converts an L-lysine residue to L-lysinoalanine." [PubMed:19155267, PubMed:2544544, RESID:AA0123#LYS]
comment	This entry is for the modification of peptidyl lysine by a free serine. For the crosslink of peptidyl serine and peptidyl lysine see MOD:00132.
synonym	"(2R,9S)-lysinoalanine" EXACT RESID-alternate []
synonym	"(2S)-2-amino-6-([(2R)-2-amino-2-carboxyethyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"alaninolysine" EXACT RESID-alternate []
synonym	"L-lysinoalanine" EXACT RESID-name []
synonym	"LAL" EXACT RESID-alternate []
synonym	"lysino-D-alanine" EXACT RESID-alternate []
synonym	"MOD_RES Lysino-D-alanine (Lys)" EXACT UniProt-feature []
synonym	"N-epsilon-(2-amino-2-carboxyethyl)-L-lysine" EXACT RESID-alternate []
synonym	"N6-(2-amino-2-carboxyethyl)-L-lysine" EXACT RESID-alternate []
xref	DiffAvg: "87.08"
xref	DiffFormula: "C 3 H 5 N 1 O 2"
xref	DiffMono: "87.032028"
xref	Formula: "C 9 H 17 N 3 O 3"
xref	MassAvg: "215.25"
xref	MassMono: "215.126991"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01853 L-lysinoalanine ! L-lysinoalanine

2.1839. MOD:01839 L-lanthionine

Table 1841. Term [MOD:01839]
id	MOD:01839
name	L-lanthionine
def	"A protein modification that effectively cross-links either two L-cysteine residues, or an L-cysteine residue and an L-serine residue by a thioether bond to form L-lanthionine." [PubMed:18688235]
comment	Cross-link 2. For the natural form of the lanthionine cross-link see MOD:00120 meso-lanthionine [JSG].
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:01841 lanthionine ! lanthionine

2.1840. MOD:01840 L-allo-isoleucine

Table 1842. Term [MOD:01840]
id	MOD:01840
name	L-allo-isoleucine
def	"A protein modification that effectively converts an L-isoleucine residue to L-allo-isoleucine." [ChEBI:43433, PubMed:20805503, RESID:AA0546]
synonym	"(2S,3R)-2-amino-3-methylpentanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-3-methylpentanoic acid" EXACT RESID-alternate []
synonym	"3-methyl-norvaline" EXACT RESID-alternate []
synonym	"allo-L-isoleucine" EXACT RESID-alternate []
synonym	"alpha-amino-beta-methylvaleric acid" EXACT RESID-alternate []
synonym	"L-allo-isoleucine" EXACT RESID-name []
synonym	"L-threo-isoleucine" EXACT RESID-alternate []
synonym	"MOD_RES L-allo-isoleucine" EXACT UniProt-feature []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 6 H 11 N 1 O 1"
xref	MassAvg: "113.16"
xref	MassMono: "113.084064"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue

2.1841. MOD:01841 lanthionine

Table 1843. Term [MOD:01841]
id	MOD:01841
name	lanthionine
def	"A protein modification that effectively cross-links either two or an L-cysteine residue and an L-serine residue by a thioether bond to form a lanthionine, either D- or L- or meso-lanthionine." [PubMed:18688235]
comment	Cross-link 2. [JSG].
synonym	"2,6-diamino-4-thiaheptanedioic acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid" EXACT PSI-MOD-alternate []
synonym	"3,3'-thiobis-(2-aminopropanoic acid)" EXACT PSI-MOD-alternate []
synonym	"3,3'-thiobis-L-alanine" EXACT PSI-MOD-alternate []
synonym	"bis(2-amino-2-carboxyethyl)sulfanediyl" EXACT PSI-MOD-alternate []
synonym	"bis(2-amino-2-carboxyethyl)sulfide" EXACT PSI-MOD-alternate []
synonym	"S-(2-amino-2-carboxyethyl)-L-cysteine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "C, X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues

2.1842. MOD:01842 S-(2-aminovinyl)-L-cysteine

Table 1844. Term [MOD:01842]
id	MOD:01842
name	S-(2-aminovinyl)-L-cysteine
def	"A protein modification that effectively converts two L-cysteine residues to S-(2-aminovinyl)-L-cysteine." [PubMed:20805503, RESID:AA0548]
comment	Cross-link 2.
synonym	"(2R)-2-amino-3-([(Z)-2-aminoethenyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(R,Z)-S-(2-aminovinyl)cysteine" EXACT RESID-alternate []
synonym	"S-(2-aminovinyl)-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "-80.10"
xref	DiffFormula: "C -1 H -4 N 0 O -2 S -1"
xref	DiffMono: "-79.993200"
xref	Formula: "C 5 H 7 N 2 O 1 S 1"
xref	MassAvg: "143.18"
xref	MassMono: "143.027909"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01851 S-(2-aminovinyl)-cysteine ! S-(2-aminovinyl)-cysteine

2.1843. MOD:01843 5'-chloro-L-tryptophan

Table 1845. Term [MOD:01843]
id	MOD:01843
name	5'-chloro-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to 5'-chloro-L-tryptophan." [PubMed:18215770, RESID:AA0549]
synonym	"(2S)-2-amino-3-(5-chloro-1H-indol-3-yl)propanoic acid" EXACT RESID-systematic []
synonym	"5'-chloro-L-tryptophan" EXACT RESID-name []
synonym	"MOD_RES 5'-chlorotryptophan" EXACT UniProt-feature []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 11 Cl 1 H 9 N 2 O 1"
xref	MassAvg: "220.66"
xref	MassMono: "220.040341"
xref	Origin: "W"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01913 monochlorinated L-tryptophan ! monochlorinated L-tryptophan

2.1844. MOD:01844 2-(3-methylbutanoyl)-5-hydroxyoxazole-4-carbothionic acid

Table 1846. Term [MOD:01844]
id	MOD:01844
name	2-(3-methylbutanoyl)-5-hydroxyoxazole-4-carbothionic acid
def	"A protein modification that effectively converts an L-cysteine residue and an L-leucine residue to 2-(3-methylbutanoyl)-5-hydroxyoxazole-4-carbothionic acid." [PubMed:15361623, PubMed:18729522, PubMed:20961038, PubMed:21254756, RESID:AA0550]
comment	Cross-link 2.
synonym	"(4Z)-4-[hydroxy(sulfanyl)methylidene]-2-(3-methylbutanoyl)-1,3-oxazol-5(4H)-one [tautomer]" EXACT RESID-alternate []
synonym	"2-(3-methylbutanoyl)-5-hydroxyoxazole-4-carbothionic acid" EXACT RESID-name []
synonym	"5-hydroxy-2-(3-methylbutanoyl)-1,3-oxazole-4-carbothioic O-acid" EXACT RESID-systematic []
synonym	"MOD_RES 2-(3-methylbutanoyl)-5-hydroxyoxazole-4-carbothionic acid (Leu-Cys)" EXACT UniProt-feature []
xref	DiffAvg: "-5.06"
xref	DiffFormula: "C 0 H -7 N -1 O 1 S 0"
xref	DiffMono: "-5.062935"
xref	Formula: "C 9 H 10 N 1 O 3 S 1"
xref	MassAvg: "212.24"
xref	MassMono: "212.038139"
xref	Origin: "C, L"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00911 modified L-leucine residue ! modified L-leucine residue
is_a	MOD:01856 oxazole/oxazoline ring crosslinked residues (Cys) ! oxazole/oxazoline ring crosslinked residues (Cys)

2.1845. MOD:01845 L-proline 5-hydroxyoxazole-4-carbothionic acid

Table 1847. Term [MOD:01845]
id	MOD:01845
name	L-proline 5-hydroxyoxazole-4-carbothionic acid
def	"A protein modification that effectively converts an L-cysteine residue and an L-proline residue to L-proline 5-hydroxyoxazole-4-carbothionic acid." [PubMed:15361623, PubMed:18729522, PubMed:20961038, PubMed:21254756, RESID:AA0551]
comment	Cross-link 2.
synonym	"(4Z)-4-[hydroxy(sulfanyl)methylidene]-2-[(2S)-pyrrolidin-2-yl]-1,3-oxazol-5(4H)-one [tautomer]" EXACT RESID-alternate []
synonym	"5-hydroxy-2-[(2S)-pyrrolidin-2-yl]-1,3-oxazole-4-carbothioic O-acid" EXACT RESID-systematic []
synonym	"CROSSLNK Proline 5-hydroxy-oxazole-4-carbothionic acid (Pro-Cys)" EXACT UniProt-feature []
synonym	"L-proline 5-hydroxy-oxazole-4-carbothionic acid" EXACT RESID-name []
xref	DiffAvg: "-4.03"
xref	DiffFormula: "C 0 H -4 N 0 O 0 S 0"
xref	DiffMono: "-4.031300"
xref	Formula: "C 8 H 8 N 2 O 2 S 1"
xref	MassAvg: "196.22"
xref	MassMono: "196.030649"
xref	Origin: "C, P"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00915 modified L-proline residue ! modified L-proline residue
is_a	MOD:01856 oxazole/oxazoline ring crosslinked residues (Cys) ! oxazole/oxazoline ring crosslinked residues (Cys)

2.1846. MOD:01846 methanobactin OB3b copper complex

Table 1848. Term [MOD:01846]
id	MOD:01846
name	methanobactin OB3b copper complex
def	"A protein modification that effectively converts two L-cysteine residues, and a copper atom to the methanobactin OB3b copper complex." [PubMed:15361623, PubMed:18729522, PubMed:20961038, PubMed:21254756, RESID:AA0552]
comment	Cross-link 2.
synonym	"bis[4-(hydroxy[sulfanyl-kappaS]methylidene)-1,3-oxazol-5(4H)-onato-kappaN]copper" EXACT RESID-systematic []
synonym	"METAL copper [Cu-methanobactin OB3b complex]" EXACT UniProt-feature []
synonym	"methanobactin OB3b copper complex" EXACT RESID-name []
xref	DiffAvg: "85.46"
xref	DiffFormula: "C 0 Cu 1 H -10 N 0 O 2 S 0"
xref	DiffMono: "84.841176"
xref	Formula: "C 6 Cu 1 H 0 N 2 O 4 S 2"
xref	MassAvg: "291.74"
xref	MassMono: "290.859546"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1847. MOD:01847 L-cysteine sulfinyl phosphate

Table 1849. Term [MOD:01847]
id	MOD:01847
name	L-cysteine sulfinyl phosphate
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine sulfinyl phosphate." [PubMed:16565085, RESID:AA0557]
synonym	"(2R)-2-amino-3-[(phosphonooxy)sulfinyl]propanoic acid" EXACT RESID-systematic []
synonym	"cysteine sulfinic phosphoryl ester" EXACT RESID-alternate []
synonym	"L-cysteine sulfinyl phosphate" EXACT RESID-name []
xref	DiffAvg: "111.98"
xref	DiffFormula: "C 0 H 1 N 0 O 5 P 1 S 0"
xref	DiffMono: "111.956160"
xref	Formula: "C 3 H 6 N 1 O 6 P 1 S 1"
xref	MassAvg: "215.12"
xref	MassMono: "214.965345"
xref	Origin: "C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00708 sulfur oxygenated L-cysteine ! sulfur oxygenated L-cysteine
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue

2.1848. MOD:01848 S-(spermidinoglutathion-S-yl)-L-cysteine

Table 1850. Term [MOD:01848]
id	MOD:01848
name	S-(spermidinoglutathion-S-yl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(spermidinoglutathion-S-yl)-L-cysteine." [ChEBI:16613, PubMed:20530482, RESID:AA0558]
synonym	"(2R)-2-amino-3-([(2R)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)-2-([2-([3-([4-aminobutyl]amino)propyl]carbamoyl)methyl]carbamoyl)ethyl]disulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"cysteine glutathionylspermidine disulfide" EXACT RESID-alternate []
synonym	"L-gamma-glutamyl-[S-(L-cystein-S-yl)]-L-cysteinyl-N-{3-[(4-aminobutyl)amino]propyl}glycinamide" EXACT RESID-alternate []
synonym	"S-(spermidinoglutathion-S-yl)-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "432.54"
xref	DiffFormula: "C 17 H 32 N 6 O 5 S 1"
xref	DiffMono: "432.215489"
xref	Formula: "C 20 H 37 N 7 O 6 S 2"
xref	MassAvg: "535.68"
xref	MassMono: "535.224674"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.1849. MOD:01849 S-(2-aminovinyl)-D-cysteine (Cys-Cys)

Table 1851. Term [MOD:01849]
id	MOD:01849
name	S-(2-aminovinyl)-D-cysteine (Cys-Cys)
def	"A protein modification that effectively cross-links two L-cysteine residues by a thioether bond to form S-(2-aminovinyl)-D-cysteine." [PubMed:20805503, RESID:AA0204#CYS2]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-([(Z)-2-aminoethenyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(S,Z)-S-(2-aminovinyl)cysteine" EXACT RESID-alternate []
synonym	"CROSSLNK S-(2-aminovinyl)-D-cysteine (Cys-Cys)" EXACT UniProt-feature []
synonym	"S-(2-aminovinyl)-D-cysteine" EXACT RESID-name []
xref	DiffAvg: "-80.10"
xref	DiffFormula: "C -1 H -4 N 0 O -2 S -1"
xref	DiffMono: "-79.993200"
xref	Formula: "C 5 H 7 N 2 O 1 S 1"
xref	MassAvg: "143.18"
xref	MassMono: "143.027909"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01850 S-(2-aminovinyl)-D-cysteine ! S-(2-aminovinyl)-D-cysteine

2.1850. MOD:01850 S-(2-aminovinyl)-D-cysteine

Table 1852. Term [MOD:01850]
id	MOD:01850
name	S-(2-aminovinyl)-D-cysteine
def	"A protein modification that effectively cross-links either two L-cysteine residues, or an L-cysteine residue and an L-serine residue by a thioether bond to form S-(2-aminovinyl)-D-cysteine." [RESID:AA0204]
comment	Cross-link 2.
synonym	"(2S)-2-amino-3-([(Z)-2-aminoethenyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(S,Z)-S-(2-aminovinyl)cysteine" EXACT RESID-alternate []
synonym	"S-(2-aminovinyl)-D-cysteine" EXACT RESID-name []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 7 N 2 O 1 S 1"
xref	MassAvg: "143.18"
xref	MassMono: "143.027909"
xref	Origin: "C, X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:01851 S-(2-aminovinyl)-cysteine ! S-(2-aminovinyl)-cysteine

2.1851. MOD:01851 S-(2-aminovinyl)-cysteine

Table 1853. Term [MOD:01851]
id	MOD:01851
name	S-(2-aminovinyl)-cysteine
def	"A protein modification that effectively cross-links either two L-cysteine residues, or an L-cysteine residue and an L-serine residue by a thioether bond to form S-(2-aminovinyl)-cysteine." [PubMed:18688235]
comment	Cross-link 2.
synonym	"2-amino-3-([2-aminoethenyl]sulfanyl)propanoic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 5 H 7 N 2 O 1 S 1"
xref	MassAvg: "143.18"
xref	MassMono: "143.027909"
xref	Origin: "C, X"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1852. MOD:01852 L-lysinoalanine (Lys-Cys)

Table 1854. Term [MOD:01852]
id	MOD:01852
name	L-lysinoalanine (Lys-Cys)
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-lysine residue to release hydrogen sulfide and form 2-amino-6-(2-amino-2-carboxyethylamino)hexanoic acid." [DeltaMass:0]
comment	Cross-link 2. This entry is for a crosslink of peptidyl cysteine and peptidyl lysine. For the modification of peptidyl lysine by a free serine see MOD:01838. From DeltaMass: Average Mass: -34 with no citation or formula. [JSG]
synonym	"Lysinoalanine (from Cysteine)" EXACT DeltaMass-label []
xref	DiffAvg: "-34.08"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S -1"
xref	DiffMono: "-33.987721"
xref	Formula: "C 9 H 15 N 3 O 2"
xref	MassAvg: "197.24"
xref	MassMono: "197.116427"
xref	Origin: "C, K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01853 L-lysinoalanine ! L-lysinoalanine

2.1853. MOD:01853 L-lysinoalanine

Table 1855. Term [MOD:01853]
id	MOD:01853
name	L-lysinoalanine
def	"A protein modification that effectively converts an L-lysine residue to L-lysinoalanine either by forming a cross-link with peptidyl-cysteine or peptidyl-serine, or by condensation with free serine." [PubMed:18688235]
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1854. MOD:01854 sulfur monooxygenated residue

Table 1856. Term [MOD:01854]
id	MOD:01854
name	sulfur monooxygenated residue
def	"A protein modification that effectively adds one oxygen atom to a sulfur atom of a residue without removing hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00680 sulfur oxygenated residue ! sulfur oxygenated residue

2.1855. MOD:01855 sulfur dioxygenated residue

Table 1857. Term [MOD:01855]
id	MOD:01855
name	sulfur dioxygenated residue
def	"A protein modification that effectively adds two oxygen atoms to a sulfur atom of a residue without removing hydrogen atoms." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:00680 sulfur oxygenated residue ! sulfur oxygenated residue

2.1856. MOD:01856 oxazole/oxazoline ring crosslinked residues (Cys)

Table 1858. Term [MOD:01856]
id	MOD:01856
name	oxazole/oxazoline ring crosslinked residues (Cys)
def	"A protein modification that crosslinks two residues by rearrangement and condensation of a cysteine with the carbonyl of the preceding residue to form a 1,3-oxazole-4-carbothionic acid." [PubMed:18688235]
is_a	MOD:01419 oxazole/oxazoline ring crosslinked residues ! oxazole/oxazoline ring crosslinked residues

2.1857. MOD:01857 2-(L-cystein-S-yl)-methionine

Table 1859. Term [MOD:01857]
id	MOD:01857
name	2-(L-cystein-S-yl)-methionine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-methionine residue by a thioether bond to form 2-(L-cystein-S-yl)-methionine." [PubMed:20805502, RESID:AA0559]
comment	Cross-link 2. The chirality around the methionine alpha-carbon has not been determined.
synonym	"(2R)-2-amino-2-([2-amino-2-carboxyethyl]sulfanyl)-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-(L-cystein-S-yl)-methionine" EXACT RESID-name []
synonym	"CROSSLNK 2-(S-cysteinyl)-methionine (Cys-Met)" EXACT UniProt-feature []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 8 H 12 N 2 O 2 S 2"
xref	MassAvg: "232.32"
xref	MassMono: "232.034020"
xref	Origin: "C, M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1858. MOD:01858 S-(N-acetylamino)glucosyl-L-cysteine

Table 1860. Term [MOD:01858]
id	MOD:01858
name	S-(N-acetylamino)glucosyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(N-acetylamino)glucosyl-L-cysteine." [ChEBI:61631, PubMed:21251913, PubMed:21395300, RESID:AA0560]
synonym	"(2R)-2-amino-3-(2-acetamido-2-deoxy-beta-D-glucopyranosylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD S-linked (GlcNAc)" EXACT UniProt-feature []
synonym	"S-(N-acetylamino)glucosyl-L-cysteine" EXACT RESID-name []
synonym	"S-[(N-acetylamino)glycosyl]cysteine" EXACT RESID-alternate []
synonym	"S-[beta-D-(N-acetylamino)glucopyranosyl]cysteine" EXACT RESID-alternate []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5 S 0"
xref	DiffMono: "203.079373"
xref	Formula: "C 11 H 18 N 2 O 6 S 1"
xref	MassAvg: "306.33"
xref	MassMono: "306.088557"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00426 S-glycosylated residue ! S-glycosylated residue
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1859. MOD:01859 4-amino-3-isothiazolidinone-L-phenylalanine

Table 1861. Term [MOD:01859]
id	MOD:01859
name	4-amino-3-isothiazolidinone-L-phenylalanine
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-phenylalanine residue to form 4-amino-3-isothiazolidinone-L-phenylalanine." [PubMed:17502599, RESID:AA0562]
comment	Cross-link 2.
synonym	"(2S)-2-[(4R)-4-amino-3-oxo-1,2-thiazolidin-2-yl]-3-phenylpropanoic acid" EXACT RESID-systematic []
synonym	"2-(4-amino-3-oxo-isothiazolidin-2-yl)-3-phenylpropanoic acid" EXACT RESID-alternate []
synonym	"4-amino-3-isothiazolidinone-L-phenylalanine" EXACT RESID-alternate []
synonym	"CROSSLNK N,N-(cysteine-1,S-diyl)phenylalanine (Cys-Phe)" EXACT UniProt-feature []
synonym	"cysteinyl phenylalanine sulfenamide" EXACT RESID-alternate []
synonym	"N,N-(L-cysteine-1,S-diyl)-L-phenylalanine" EXACT RESID-name []
synonym	"phenylalanine-cysteine sulfenyl amide cross-link" EXACT RESID-alternate []
synonym	"phenylalanine-cysteine sulphenyl amide cross-link" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 2 S 1"
xref	MassAvg: "248.30"
xref	MassMono: "248.061949"
xref	Origin: "C, F"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:01861 isothiazolidinone ring crosslinked residues ! isothiazolidinone ring crosslinked residues

2.1860. MOD:01860 L-cysteine bacillithiol disulfide

Table 1862. Term [MOD:01860]
id	MOD:01860
name	L-cysteine bacillithiol disulfide
def	"A protein modification that effectively converts an L-cysteine residue to L-cysteine bacillithiol disulfide." [ChEBI:61338, PubMed:19578333, RESID:AA0563]
synonym	"(2S)-(2-[S-(L-cystein-S-yl)-L-cysteinyl]amino-2-deoxy-alpha-D-glucopyranosyloxy)-butanedioic acid" EXACT RESID-systematic []
synonym	"BSH" EXACT RESID-alternate []
synonym	"L-cysteine bacillithiol disulfide" EXACT RESID-name []
synonym	"MOD_RES S-bacillithiol cysteine disulfide" EXACT UniProt-feature []
xref	DiffAvg: "396.37"
xref	DiffFormula: "C 13 H 20 N 2 O 10 S 1"
xref	DiffMono: "396.083866"
xref	Formula: "C 16 H 25 N 3 O 11 S 2"
xref	MassAvg: "499.51"
xref	MassMono: "499.093051"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01862 disulfide conjugated residue ! disulfide conjugated residue

2.1861. MOD:01861 isothiazolidinone ring crosslinked residues

Table 1863. Term [MOD:01861]
id	MOD:01861
name	isothiazolidinone ring crosslinked residues
def	"A protein modification that crosslinks two residues by condensation of a cysteine thiol with the amido nitrogen of the following residue to form an isothiazolidinone ring." [PubMed:18688235]
comment	The isothiazolidinone ring is usually formed by the reaction of a cysteine sulfenic acid with the amido nitrogen releasing water.
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.1862. MOD:01862 disulfide conjugated residue

Table 1864. Term [MOD:01862]
id	MOD:01862
name	disulfide conjugated residue
def	"A protein modification that effectively replaces the hydrogen atom of a cysteine sulfanyl group with a substituted sulfanyl group, forming a disulfide bond that does not cross-link two encoded peptide chains." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"S-thiolation" EXACT PSI-MOD-alternate []
xref	Origin: "C"
xref	TermSpec: "none"
is_a	MOD:01886 thiolated residue ! thiolated residue

2.1863. MOD:01863 mTRAQ reporter+balance reagent acylated residue

Table 1865. Term [MOD:01863]
id	MOD:01863
name	mTRAQ reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with one of the Applied Biosystems mTRAQ reagent reporter+balance groups." [PubMed:18688235]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue
is_a	MOD:01705 isotope tagged reagent acylated residue ! isotope tagged reagent acylated residue

2.1864. MOD:01864 mTRAQ light reporter+balance reagent acylated residue

Table 1866. Term [MOD:01864]
id	MOD:01864
name	mTRAQ light reporter+balance reagent acylated residue
def	"A protein modification that effectively replaces a hydrogen atom of a residue with the Applied Biosystems mTRAQ light reporter+balance group." [UniMod:888]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"mTRAQ heavy" RELATED UniMod-description []
xref	DiffAvg: "140.09"
xref	DiffFormula: "(12)C 7 H 12 (14)N 2 (16)O 1"
xref	DiffMono: "140.094963"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01863 mTRAQ reporter+balance reagent acylated residue ! mTRAQ reporter+balance reagent acylated residue
is_a	MOD:01868 modifications with monoisotopic mass differences that are nominally equal at 140.094963 Da ! modifications with monoisotopic mass differences that are nominally equal at 140.094963 Da

2.1865. MOD:01865 mTRAQ light reporter+balance reagent acylated N-terminal

Table 1867. Term [MOD:01865]
id	MOD:01865
name	mTRAQ light reporter+balance reagent acylated N-terminal
def	"A protein modification that effectively replaces a hydrogen atom of a protein N-terminal with the Applied Biosystems mTRAQ light reporter+balance group." [OMSSA:208, UniMod:888#N-term]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"mTRAQ light" RELATED UniMod-description []
synonym	"mTRAQ light on nterm" EXACT OMSSA-label []
xref	DiffAvg: "140.09"
xref	DiffFormula: "(12)C 7 H 12 (14)N 2 (16)O 1"
xref	DiffMono: "140.094963"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01864 mTRAQ light reporter+balance reagent acylated residue ! mTRAQ light reporter+balance reagent acylated residue

2.1866. MOD:01866 mTRAQ light reporter+balance reagent N6-acylated lysine

Table 1868. Term [MOD:01866]
id	MOD:01866
name	mTRAQ light reporter+balance reagent N6-acylated lysine
def	"A protein modification that effectively replaces the N6-amino hydrogen atom of a lysine residue with the Applied Biosystems mTRAQ light reporter+balance group." [OMSSA:209, UniMod:888#K]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
subset	PSI-MOD-slim
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"mTRAQ light" RELATED UniMod-description []
synonym	"mTRAQ light on K" EXACT OMSSA-label []
xref	DiffAvg: "140.09"
xref	DiffFormula: "(12)C 7 H 12 (14)N 2 (16)O 1"
xref	DiffMono: "140.094963"
xref	Formula: "(12)C 13 H 24 N 2 (14)N 2 O 1 (16)O 1"
xref	MassAvg: "268.19"
xref	MassMono: "268.189926"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01864 mTRAQ light reporter+balance reagent acylated residue ! mTRAQ light reporter+balance reagent acylated residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1867. MOD:01867 mTRAQ light reporter+balance reagent O4'-acylated tyrosine

Table 1869. Term [MOD:01867]
id	MOD:01867
name	mTRAQ light reporter+balance reagent O4'-acylated tyrosine
def	"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems mTRAQ light reporter+balance group." [OMSSA:210, UniMod:888#Y]
comment	The reagent consists of a reporter group, a balance group and a protein reactive N-oxysuccinimide group. The reporter group, an isotopically labeled 1,4-dimethylpiperazine, is connected to a carbonyl balance group that is isotopically labeled to produce a nominally isobaric combined modification.
synonym	"(4-methylpiperazin-1-yl)acetyl" EXACT PSI-MOD-alternate []
synonym	"Applied Biosystems mTRAQ™ reagent" RELATED UniMod-alternate []
synonym	"mTRAQ light" RELATED UniMod-description []
synonym	"mTRAQ light on Y" EXACT OMSSA-label []
xref	DiffAvg: "140.09"
xref	DiffFormula: "(12)C 7 H 12 (14)N 2 (16)O 1"
xref	DiffMono: "140.094963"
xref	Formula: "(12)C 16 H 21 (14)N 3 O 2 (16)O 1"
xref	MassAvg: "303.16"
xref	MassMono: "303.158292"
xref	Origin: "Y"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01864 mTRAQ light reporter+balance reagent acylated residue ! mTRAQ light reporter+balance reagent acylated residue

2.1868. MOD:01868 modifications with monoisotopic mass differences that are nominally equal at 140.094963 Da

Table 1870. Term [MOD:01868]
id	MOD:01868
name	modifications with monoisotopic mass differences that are nominally equal at 140.094963 Da
def	"Modifications that have monoisotopic mass differences from their respective origins of 140.094963 Da." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01515 modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da ! modifications with monoisotopic mass differences that are nominally equal at a resolution below 0.000001 Da

2.1869. MOD:01869 mTRAQ light reporter fragment

Table 1871. Term [MOD:01869]
id	MOD:01869
name	mTRAQ light reporter fragment
def	"The protein modification reporter fragment produced by an Applied Biosystems mTRAQ light reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"4-methyl-1-methylidenepiperazin-1-ium" EXACT PSI-MOD-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	FormalCharge: "1+"
xref	Formula: "(12)C 6 H 13 (14)N 2"
xref	MassAvg: "113.11"
xref	MassMono: "113.107325"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01870 mTRAQ reporter fragment ! mTRAQ reporter fragment
relationship	derives_from MOD:01864 mTRAQ light reporter+balance reagent acylated residue ! mTRAQ light reporter+balance reagent acylated residue

2.1870. MOD:01870 mTRAQ reporter fragment

Table 1872. Term [MOD:01870]
id	MOD:01870
name	mTRAQ reporter fragment
def	"A protein modification reporter fragment produced by an Applied Biosystems mTRAQ reagent derivatized residue." [PubMed:18688235]
subset	PSI-MOD-slim
is_a	MOD:01520 modification reporter fragment ! modification reporter fragment

2.1871. MOD:01871 cyclized N-terminal S-carboxamidomethyl-L-cysteine

Table 1873. Term [MOD:01871]
id	MOD:01871
name	cyclized N-terminal S-carboxamidomethyl-L-cysteine
def	"A protein modification that effectively cyclizes an S-carboxamidomethyl-L-cysteine residue to ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid with the loss of ammonia." [DeltaMass:336, PubMed:12643538, UniMod:26]
subset	PSI-MOD-slim
synonym	"®-5-oxoperhydro-1,4-thiazine-3-carboxylic acid" EXACT DeltaMass-label []
synonym	"5-oxothiomorpholine-3-carboxylic acid" EXACT PSI-MOD-alternate []
synonym	"Otc" EXACT DeltaMass-label []
synonym	"Pyro-carbamidomethyl" RELATED UniMod-interim []
synonym	"S-carbamoylmethylcysteine cyclization (N-terminus)" RELATED UniMod-description []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0 S 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 5 H 6 N 1 O 2 S 1"
xref	MassAvg: "144.17"
xref	MassMono: "144.011924"
xref	Origin: "MOD:01060"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00397 iodoacetamide derivatized residue ! iodoacetamide derivatized residue
is_a	MOD:00419 ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid ! ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid
relationship	derives_from MOD:01060 S-carboxamidomethyl-L-cysteine ! S-carboxamidomethyl-L-cysteine

2.1872. MOD:01872 cyclized N-terminal S-carboxymethyl-L-cysteine

Table 1874. Term [MOD:01872]
id	MOD:01872
name	cyclized N-terminal S-carboxymethyl-L-cysteine
def	"A protein modification that effectively cyclizes an S-carboxymethyl-L-cysteine residue to ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid with the loss of water." [PubMed:12643538, UniMod:26]
comment	Contrary to the impression given in UniMod entry 26, the cyclization of N-terminal S-carboxymethyl-L-cysteine is not reported in PubMed:1263538. The cyclization would be expected to proceed under strongly acidic conditions [JSG].
subset	PSI-MOD-slim
synonym	"®-5-oxoperhydro-1,4-thiazine-3-carboxylic acid" EXACT DeltaMass-label []
synonym	"5-oxothiomorpholine-3-carboxylic acid" EXACT PSI-MOD-alternate []
synonym	"Otc" EXACT DeltaMass-label []
synonym	"Pyro-carbamidomethyl" RELATED UniMod-interim []
synonym	"S-carbamoylmethylcysteine cyclization (N-terminus)" RELATED UniMod-description []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 5 H 6 N 1 O 2 S 1"
xref	MassAvg: "144.17"
xref	MassMono: "144.011924"
xref	Origin: "MOD:01061"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00399 iodoacetic acid derivatized residue ! iodoacetic acid derivatized residue
is_a	MOD:00419 ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid ! ®-5-oxo-1,4-tetrahydrothiazine-3-carboxylic acid
relationship	derives_from MOD:01061 S-carboxymethyl-L-cysteine ! S-carboxymethyl-L-cysteine

2.1873. MOD:01873 N-carboxy-L-alanine

Table 1875. Term [MOD:01873]
id	MOD:01873
name	N-carboxy-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N-carboxy-L-alanine." [PubMed:18688235, PubMed:4593770, PubMed:4647257, PubMed:8312270]
comment	This metastable modification can be formed by a protein N-terminal in solutions with a high concentration of dissolved carbon dioxide [JSG].
synonym	"(S)-2-carboxyamino-propanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-carbamic-propanoic acid" EXACT PSI-MOD-alternate []
synonym	"N-carboxymethionine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 4 H 6 N 1 O 3"
xref	MassAvg: "116.10"
xref	MassMono: "116.034768"
xref	Origin: "A"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.1874. MOD:01874 N-carboxy-L-valine

Table 1876. Term [MOD:01874]
id	MOD:01874
name	N-carboxy-L-valine
def	"A protein modification that effectively converts an L-alanine residue to N-carboxy-L-valine." [PubMed:18688235, PubMed:4593770, PubMed:4647257, PubMed:8312270]
comment	This metastable modification can be formed by a protein N-terminal in solutions with a high concentration of dissolved carbon dioxide [JSG].
synonym	"(S)-2-carboxyamino-propanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-carbamic-propanoic acid" EXACT PSI-MOD-alternate []
synonym	"N-carboxymethionine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "44.01"
xref	DiffFormula: "C 1 H 0 N 0 O 2"
xref	DiffMono: "43.989829"
xref	Formula: "C 6 H 10 N 1 O 3"
xref	MassAvg: "144.15"
xref	MassMono: "144.066068"
xref	Origin: "V"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue
is_a	MOD:01152 carboxylated residue ! carboxylated residue

2.1875. MOD:01875 N6-acylated L-lysine

Table 1877. Term [MOD:01875]
id	MOD:01875
name	N6-acylated L-lysine
def	"A protein modification that effectively replaces an N6-amino hydrogen atom of L-lysine with an acyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"N6AcylLys" EXACT PSI-MOD-label []
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00670 N-acylated residue ! N-acylated residue
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.1876. MOD:01876 4x(1)H,4x(12)C-labeled alpha-amino succinylated residue

Table 1878. Term [MOD:01876]
id	MOD:01876
name	4x(1)H,4x(12)C-labeled alpha-amino succinylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a 4x(12)C labeled succinyl group." [PubMed:11857757, PubMed:12175151, PubMed:12716131, UniMod:64]
synonym	"Succinic anhydride labeling reagent, light form (+4amu, 4H2) site N-term" RELATED UniMod-description []
synonym	"Succinyl" RELATED PSI-MS-label []
xref	DiffAvg: "100.02"
xref	DiffFormula: "(12)C 4 (1)H 4 O 3"
xref	DiffMono: "100.016044"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00457 alpha-amino succinylated residue ! alpha-amino succinylated residue
is_a	MOD:01426 isotope tagged reagent derivatized residue ! isotope tagged reagent derivatized residue

2.1877. MOD:01877 2-(4-guanidinobutanoyl)-5-hydroxyimidazole-4-carbothionic acid

Table 1879. Term [MOD:01877]
id	MOD:01877
name	2-(4-guanidinobutanoyl)-5-hydroxyimidazole-4-carbothionic acid
def	"A protein modification that effectively converts an L-cysteine residue and an L-arginine residue to 2-(4-guanidinobutanoyl)-5-hydroxyimidazole-4-carbothionic acid." [PubMed:20961038, RESID:AA0553]
comment	Cross-link 2.
synonym	"(4Z)-2-(4-guanidinobutanoyl)-5-oxo-4-(sulfanylmethylidene)-4,5-dihydro-1H-imidazole" EXACT RESID-alternate []
synonym	"2-(4-guanidinobutanoyl)-5-hydroxy-1H-imidazole-4-carbothioic O-acid" EXACT RESID-systematic []
synonym	"2-(4-guanidinobutanoyl)-5-hydroxy-4-thioformyl-1H-imidazole [tautomer]" EXACT RESID-alternate []
synonym	"2-(4-guanidinobutanoyl)-5-hydroxyimidazole-4-carbothionic acid" EXACT RESID-name []
synonym	"CROSSLNK 2-(4-guanidinobutanoyl)-5-hydroxyimidazole-4-carbothionic acid (Arg-Cys)" EXACT UniProt-feature []
xref	DiffAvg: "-6.05"
xref	DiffFormula: "C 0 H -6 N 0 O 0 S 0"
xref	DiffMono: "-6.046950"
xref	Formula: "C 9 H 12 N 5 O 2 S 1"
xref	MassAvg: "254.29"
xref	MassMono: "254.071171"
xref	Origin: "C, R"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01883 5-imidazolinone ring crosslinked residues (Cys) ! 5-imidazolinone ring crosslinked residues (Cys)

2.1878. MOD:01878 L-threonine 5-hydroxyoxazole-4-carbonthionic acid

Table 1880. Term [MOD:01878]
id	MOD:01878
name	L-threonine 5-hydroxyoxazole-4-carbonthionic acid
def	"A protein modification that effectively converts an L-cysteine residue and an L-threonine residue to L-threonine 5-hydroxyoxazole-4-carbothionic acid." [PubMed:20961038, RESID:AA0554]
comment	Cross-link 2.
synonym	"(4Z)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-4-(sulfanylmethylidene)-1,3-oxazol-5(4H)-one [tautomer]" EXACT RESID-alternate []
synonym	"2-[(1S,2R)-1-amino-2-hydroxypropyl]-5-hydroxy-1,3-oxazole-4-carbothioic O-acid" EXACT RESID-systematic []
synonym	"CROSSLNK Threonine 5-hydroxy-oxazole-4-carbonthionic acid (Thr-Cys)" EXACT UniProt-feature []
synonym	"L-threonine 5-hydroxy-oxazole-4-carbonthionic acid" EXACT RESID-name []
xref	DiffAvg: "-4.03"
xref	DiffFormula: "C 0 H -4 N 0 O 0 S 0"
xref	DiffMono: "-4.031300"
xref	Formula: "C 7 H 8 N 2 O 3 S 1"
xref	MassAvg: "200.21"
xref	MassMono: "200.025563"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01856 oxazole/oxazoline ring crosslinked residues (Cys) ! oxazole/oxazoline ring crosslinked residues (Cys)

2.1879. MOD:01879 methanobactin SB2 copper complex

Table 1881. Term [MOD:01879]
id	MOD:01879
name	methanobactin SB2 copper complex
def	"A protein modification that effectively converts two L-cysteine residues, an L-arginine residue, an L-threonine residue and a copper atom to the methanobactin SB2 copper complex." [PubMed:20961038, RESID:AA0555]
comment	Cross-link 2.
synonym	"[5-(hydroxy[sulfanyl-kappaS]methylene)-3,5-dihydro-4H-imidazol-4-onato-kappaN1][4-(hydroxy[sulfanyl-kappaS]methylene)-1,3-oxazol-5(4H)-onato-kappaN]copper" EXACT RESID-systematic []
synonym	"METAL copper [Cu-methanobactin SB2 complex]" EXACT UniProt-feature []
synonym	"methanobactin SB2 copper complex" EXACT RESID-name []
xref	DiffAvg: "84.48"
xref	DiffFormula: "C 0 Cu 1 H -9 N 1 O 1 S 0"
xref	DiffMono: "83.857161"
xref	Formula: "C 6 Cu 1 H 1 N 3 O 3 S 2"
xref	MassAvg: "290.76"
xref	MassMono: "289.875530"
xref	Origin: "C, C, R, T"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00742 copper containing modified residue ! copper containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1880. MOD:01880 L-deoxyhypusine

Table 1882. Term [MOD:01880]
id	MOD:01880
name	L-deoxyhypusine
def	"modification from RESID" [ChEBI:50038, PubMed:16452303, RESID:AA0564]
synonym	"(2S)-2-amino-6-[(4-aminobutyl)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"deoxyhypusine" EXACT RESID-alternate []
synonym	"L-deoxyhypusine" EXACT RESID-name []
synonym	"N6-(4-aminobutyl)lysine" EXACT RESID-alternate []
xref	DiffAvg: "71.12"
xref	DiffFormula: "C 4 H 9 N 1 O 0"
xref	DiffMono: "71.073499"
xref	Formula: "C 10 H 21 N 3 O 1"
xref	MassAvg: "199.30"
xref	MassMono: "199.168462"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01884 4-aminobutylated residue ! 4-aminobutylated residue

2.1881. MOD:01881 3-(L-phenylalan-2'-yl)-L-valine

Table 1883. Term [MOD:01881]
id	MOD:01881
name	3-(L-phenylalan-2'-yl)-L-valine
def	"A protein modification that effectively crosslinks an L-phenylalanine residue and an L-valine residue by a free radical process effectively releasing a hydrogen molecule and forming 3-(L-phenylalan-2'-yl)-L-valine." [PubMed:21596985, RESID:AA0565]
comment	Cross-link 2.
synonym	"(2S)-2-amino-4-(2-[(2S)-2-amino-2-carboxyethyl]phenyl)-3-methylbutanoic acid" EXACT RESID-systematic []
synonym	"3-(L-phenylalan-2'-yl)-L-valine" EXACT RESID-name []
synonym	"symerythrin valine-phenylalanine cross-link" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 14 H 16 N 2 O 2"
xref	MassAvg: "244.29"
xref	MassMono: "244.121178"
xref	Origin: "F, V"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00692 uncategorized crosslinked residues ! uncategorized crosslinked residues
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:00920 modified L-valine residue ! modified L-valine residue

2.1882. MOD:01882 5-imidazolinone ring crosslinked residues (Gly)

Table 1884. Term [MOD:01882]
id	MOD:01882
name	5-imidazolinone ring crosslinked residues (Gly)
def	"A protein modification that effectively crosslinks the carbonyl of an amino acid residue at position n with the alpha amino of a glycine residue at position n+2 to form a 5-imidazolinone ring." [PubMed:18688235]
is_a	MOD:00691 5-imidazolinone ring crosslinked residues ! 5-imidazolinone ring crosslinked residues

2.1883. MOD:01883 5-imidazolinone ring crosslinked residues (Cys)

Table 1885. Term [MOD:01883]
id	MOD:01883
name	5-imidazolinone ring crosslinked residues (Cys)
def	"A protein modification that crosslinks two residues by rearrangement and condensation of a cysteine with the carbonyl of the preceding residue to form a 5-imidazolinone ring." [PubMed:18688235]
is_a	MOD:00691 5-imidazolinone ring crosslinked residues ! 5-imidazolinone ring crosslinked residues

2.1884. MOD:01884 4-aminobutylated residue

Table 1886. Term [MOD:01884]
id	MOD:01884
name	4-aminobutylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a 4-aminobutyl group, usually derived from spermidine." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00001 alkylated residue ! alkylated residue

2.1885. MOD:01885 biotinylated residue

Table 1887. Term [MOD:01885]
id	MOD:01885
name	biotinylated residue
def	"A protein modification that effectively replaces a hydrogen atom with a biotinyl group." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"5-((3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl" EXACT PSI-MOD-alternate []
synonym	"Biotinylation" EXACT PSI-MOD-alternate []
synonym	"BtnRes" EXACT PSI-MOD-label []
xref	DiffAvg: "226.29"
xref	DiffFormula: "C 10 H 14 N 2 O 2 S 1"
xref	DiffMono: "226.077599"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1886. MOD:01886 thiolated residue

Table 1888. Term [MOD:01886]
id	MOD:01886
name	thiolated residue
def	"A protein modification that effectively replaces a hydrogen atom with an sulfanyl or substituted sulfanyl group." [PubMed:18688235]
subset	PSI-MOD-slim
xref	Origin: "X"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue

2.1887. MOD:01887 Uniblue A derivatized lysine

Table 1889. Term [MOD:01887]
id	MOD:01887
name	Uniblue A derivatized lysine
def	"A protein modification that is produced by reaction with 1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate, Uniblue A, to form Uniblue A lysine adduct." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"1-amino-4-{[3-(ethenylsulfonyl)phenyl]amino}-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate" EXACT PSI-MOD-alternate []
synonym	"1-amino-9,10-dioxo-4-{[3-(vinylsulfonyl)phenyl]amino}-9,10-dihydroanthracene-2-sulfonate" EXACT PSI-MOD-alternate []
synonym	"N6UniblueALys" EXACT PSI-MOD-label []
synonym	"Uniblue A" EXACT PSI-MOD-alternate []
xref	DiffAvg: "484.50"
xref	DiffFormula: "C 22 H 16 N 2 O 7 S 2"
xref	DiffMono: "484.039893"
xref	Formula: "C 28 H 28 N 4 O 8 S 2"
xref	MassAvg: "612.67"
xref	MassMono: "612.134856"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01659 Uniblue A derivatized residue ! Uniblue A derivatized residue

2.1888. MOD:01888 didehydrogenated residue

Table 1890. Term [MOD:01888]
id	MOD:01888
name	didehydrogenated residue
def	"A protein modification that effectively removes two neutral hydrogen atoms (proton and electron) from a residue." [UniMod:401]
subset	PSI-MOD-slim
synonym	"2dHRes" EXACT PSI-MOD-label []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0"
xref	DiffMono: "-2.015650"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00683 dehydrogenated residue ! dehydrogenated residue

2.1889. MOD:01889 S-(2-succinyl)-L-cysteine

Table 1891. Term [MOD:01889]
id	MOD:01889
name	S-(2-succinyl)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(2-succinyl)-L-cysteine, by addition of either fumaric acid or maleic acid." [PubMed:16624247, PubMed:18448829, PubMed:20677745, RESID:AA0561, UniMod:957]
synonym	"(2R)-2-amino-3-([(1R)-1,2-dicarboxyethyl]sulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"(2R)-2-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}butanedioic acid" EXACT RESID-alternate []
synonym	"2-((2-amino-2-carboxyethyl)thio)butanedioic acid" EXACT RESID-alternate []
synonym	"2-amino-3-(1,2-dicarboxyethylthio)propanoic acid" EXACT RESID-alternate []
synonym	"S-(1,2-dicarboxyethyl)cysteine" EXACT RESID-alternate []
synonym	"S-(2-succinyl)-L-cysteine" EXACT RESID-name []
synonym	"S-(2-succinyl)cysteine" EXACT RESID-alternate []
synonym	"S-[(2R)-2-succinyl]-L-cysteine" EXACT RESID-alternate []
xref	DiffAvg: "116.07"
xref	DiffFormula: "C 4 H 4 N 0 O 4 S 0"
xref	DiffMono: "116.010959"
xref	Formula: "C 7 H 9 N 1 O 5 S 1"
xref	MassAvg: "219.21"
xref	MassMono: "219.020143"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00001 alkylated residue ! alkylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1890. MOD:01890 N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet)

Table 1892. Term [MOD:01890]
id	MOD:01890
name	N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet)
def	"A protein modification that effectively crosslinks an N-formyl-L-methionine residue and an L-histidine residue to form N-[(L-histidin-1'-yl)methyl]-L-methionine." [PubMed:19622680, RESID:AA0566#FMET]
comment	Cross-link 2.
synonym	"(2S)-2-([(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl)methyl]amino)-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"N-[(L-histidin-1'-yl)methyl]-L-methionine" EXACT RESID-name []
xref	DiffAvg: "-16.00"
xref	DiffFormula: "C 0 H 0 N 0 O -1 S 0"
xref	DiffMono: "-15.994915"
xref	Formula: "C 12 H 17 N 4 O 2 S 1"
xref	MassAvg: "281.35"
xref	MassMono: "281.107222"
xref	Origin: "H, MOD:00030"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01450 modified N-formyl-L-methionine residue ! modified N-formyl-L-methionine residue

2.1891. MOD:01891 N-[(L-histidin-1'-yl)methyl]-L-methionine (Met)

Table 1893. Term [MOD:01891]
id	MOD:01891
name	N-[(L-histidin-1'-yl)methyl]-L-methionine (Met)
def	"A protein modification that effectively crosslinks an L-methionine residue and an L-histidine residue to form N-[(L-histidin-1'-yl)methyl]-L-methionine." [PubMed:19622680, RESID:AA0566#MET]
comment	Cross-link 2.
synonym	"(2S)-2-([(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl)methyl]amino)-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"N-[(L-histidin-1'-yl)methyl]-L-methionine" EXACT RESID-name []
xref	DiffAvg: "12.01"
xref	DiffFormula: "C 1 H 0 N 0 O 0 S 0"
xref	DiffMono: "12.000000"
xref	Formula: "C 12 H 17 N 4 O 2 S 1"
xref	MassAvg: "281.35"
xref	MassMono: "281.107222"
xref	Origin: "H, M"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.1892. MOD:01892 N6-crotonyl-L-lysine

Table 1894. Term [MOD:01892]
id	MOD:01892
name	N6-crotonyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-crotonyl-L-lysine." [PubMed:21925322, RESID:AA0567]
synonym	"(2S)-2-amino-6-[(2E)-but-2-enamido]hexanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-6-[(2E)-but-2-enoylamino]hexanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-azanyl-6-[(2E)-but-2-enoylazanyl]hexanoic acid" EXACT RESID-alternate []
synonym	"MOD_RES N6-crotonyl-L-lysine" EXACT UniProt-feature []
synonym	"N(epsilon)-crotonyllysine" EXACT RESID-alternate []
synonym	"N6-(E)-crotonyllysine" EXACT RESID-alternate []
synonym	"N6-[(2E)-2-butenoyl]-L-lysine" EXACT RESID-alternate []
synonym	"N6-crotonyl-L-lysine" EXACT RESID-name []
synonym	"N6-crotonyllysine" EXACT RESID-alternate []
synonym	"N6-trans-crotonyllysine" EXACT RESID-alternate []
xref	DiffAvg: "68.07"
xref	DiffFormula: "C 4 H 4 N 0 O 1"
xref	DiffMono: "68.026215"
xref	Formula: "C 10 H 16 N 2 O 2"
xref	MassAvg: "196.25"
xref	MassMono: "196.121178"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1893. MOD:01893 N6-malonyl-L-lysine

Table 1895. Term [MOD:01893]
id	MOD:01893
name	N6-malonyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-malonyl-L-lysine." [PubMed:21908771, PubMed:8349414, RESID:AA0568]
synonym	"(2S)-2-amino-6-[(carboxyacetyl)amino]hexanoic acid" EXACT RESID-systematic []
synonym	"2-azanyl-6-[(carboxyacetyl)azanyl]hexanoic acid" EXACT RESID-alternate []
synonym	"malonyllysine" EXACT RESID-alternate []
synonym	"MOD_RES N6-malonyllysine" EXACT UniProt-feature []
synonym	"N(epsilon)-(malonyl)lysine" EXACT RESID-alternate []
synonym	"N6-(carboxyacetyl)lysine" EXACT RESID-alternate []
synonym	"N6-malonyl-L-lysine" EXACT RESID-name []
synonym	"N6-malonyllysine" EXACT RESID-alternate []
xref	DiffAvg: "86.05"
xref	DiffFormula: "C 3 H 2 N 0 O 3"
xref	DiffMono: "86.000394"
xref	Formula: "C 9 H 14 N 2 O 4"
xref	MassAvg: "214.22"
xref	MassMono: "214.095357"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1894. MOD:01894 propanoylated residue

Table 1896. Term [MOD:01894]
id	MOD:01894
name	propanoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an propanoyl group." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:58]
synonym	"Propionate labeling reagent light form (N-term & K)" RELATED UniMod-description []
synonym	"Propionyl" RELATED PSI-MS-label []
xref	DiffAvg: "56.06"
xref	DiffFormula: "C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1895. MOD:01895 alpha-amino 3x(12)C-labeled propanoylated residue

Table 1897. Term [MOD:01895]
id	MOD:01895
name	alpha-amino 3x(12)C-labeled propanoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a 3x(12)C-labeled propanoyl group." [PubMed:11857757, PubMed:11999733, PubMed:12175151, UniMod:58#N-term]
synonym	"Propionate labeling reagent light form (N-term & K)" RELATED UniMod-description []
synonym	"Propionyl" RELATED PSI-MS-label []
xref	DiffAvg: "56.03"
xref	DiffFormula: "(12)C 3 H 4 O 1"
xref	DiffMono: "56.026215"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00451 alpha-amino propanoylated residue ! alpha-amino propanoylated residue

2.1896. MOD:01896 trifluoroacetic acid adduct

Table 1898. Term [MOD:01896]
id	MOD:01896
name	trifluoroacetic acid adduct
def	"A protein modification produced by trifluoroacetic acid forming an adduct, either a salt or a hydrogen bonded carboxylic acid dimer, with an amino acid residue." [PubMed:18688235]
comment	Trifluoroacetic acid has been observed to form adducts in both negative and positive mode analysis (Mark Collins, private communication) [JSG].
synonym	"TFA" EXACT DeltaMass-label []
xref	DiffAvg: "114.02"
xref	DiffFormula: "C 2 F 3 H 1 O 2"
xref	DiffMono: "113.992864"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue
is_a	MOD:00848 reagent derivatized residue ! reagent derivatized residue

2.1897. MOD:01897 5-hydroxy-3-methyl-L-proline (Ile)

Table 1899. Term [MOD:01897]
id	MOD:01897
name	5-hydroxy-3-methyl-L-proline (Ile)
def	"A protein modification that effectively converts an L-isoleucine residue to 5-hydroxy-3-methyl-L-proline." [PubMed:21788474, PubMed:7592021, PubMed:8557573, RESID:AA0473]
synonym	"(2S,3S,5Xi)-5-hydroxy-3-methylpyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"5-hydroxy-3-methyl-L-proline" EXACT RESID-name []
synonym	"5-hydroxy-3-methylproline" EXACT RESID-alternate []
synonym	"5Hy3MePro(Ile)" EXACT PSI-MOD-label []
synonym	"beta-methyl-delta-hydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES 5-hydroxy-3-methylproline (Ile)" EXACT UniProt-feature []
xref	DiffAvg: "13.98"
xref	DiffFormula: "C 0 H -2 N 0 O 1"
xref	DiffMono: "13.979265"
xref	Formula: "C 6 H 9 N 1 O 2"
xref	MassAvg: "127.14"
xref	MassMono: "127.063329"
xref	Origin: "I"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00679 carbon oxygenated residue ! carbon oxygenated residue
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue
is_a	MOD:01905 5-hydroxy-3-methyl-L-proline ! 5-hydroxy-3-methyl-L-proline

2.1898. MOD:01898 N2,N2-dimethyl-L-arginine

Table 1900. Term [MOD:01898]
id	MOD:01898
name	N2,N2-dimethyl-L-arginine
def	"modification from RESID" [PubMed:21568297, PubMed:21950656, RESID:AA0569]
synonym	"(2S)-5-[(diaminomethylidene)amino]-2-(dimethylamino)pentanoic acid" EXACT RESID-systematic []
synonym	"(2S)-5-carbamimidamido-2-(dimethylamino)pentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"MOD_RES N2,N2-dimethylarginine" EXACT UniProt-feature []
synonym	"N(alpha),N(alpha)-dimethylarginine" EXACT RESID-alternate []
synonym	"N2,N2-dimethyl-L-arginine" EXACT RESID-name []
synonym	"N2,N2-dimethylarginine" EXACT RESID-alternate []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 8 H 17 N 4 O 1"
xref	MassAvg: "185.25"
xref	MassMono: "185.140236"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00783 dimethylated L-arginine ! dimethylated L-arginine

2.1899. MOD:01899 L-arginine thiazole-4-carboxylic acid

Table 1901. Term [MOD:01899]
id	MOD:01899
name	L-arginine thiazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-arginine residue and an L-cysteine residue to form arginine thiazole-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0570]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-4-([diaminomethylidene]amino)butyl]-1,3-thiazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"CROSSLNK Thiazole-4-carboxylic acid (Arg-Cys)" EXACT UniProt-feature []
synonym	"L-arginine thiazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 9 H 13 N 5 O 1 S 1"
xref	MassAvg: "239.30"
xref	MassMono: "239.084081"
xref	Origin: "C, R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue
is_a	MOD:01420 thiazole/thiazoline ring croslinked residues ! thiazole/thiazoline ring croslinked residues
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1900. MOD:01900 L-cysteine 5-methyloxazole-4-carboxylic acid

Table 1902. Term [MOD:01900]
id	MOD:01900
name	L-cysteine 5-methyloxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-cysteine residue and an L-threonine residue to form L-cysteine 5-methyloxazole-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0571]
comment	Cross-link 2.
synonym	"2-[(1R)-1-amino-2-sulfanylethyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[(1R)-1-azanyl-2-sulfanylethyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 5-methyloxazole-4-carboxylic acid (Cys-Thr)" EXACT UniProt-feature []
synonym	"L-cysteine 5-methyloxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1 S 0"
xref	DiffMono: "-20.026215"
xref	Formula: "C 7 H 8 N 2 O 2 S 1"
xref	MassAvg: "184.21"
xref	MassMono: "184.030649"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01422 oxazole/oxazoline ring crosslinked residues (Thr) ! oxazole/oxazoline ring crosslinked residues (Thr)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1901. MOD:01901 L-threonine 5-methyloxazole-4-carboxylic acid

Table 1903. Term [MOD:01901]
id	MOD:01901
name	L-threonine 5-methyloxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks two L-threonine residues to form L-threonine 5-methyloxazole-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0572]
comment	Cross-link 2.
synonym	"2-[(1S,2R)-1-amino-2-hydroxypropyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[(1S,2R)-1-azanyl-2-hydroxypropyl]-5-methyl-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 5-methyloxazole-4-carboxylic acid (Thr-Thr)" EXACT UniProt-feature []
synonym	"L-threonine 5-methyloxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 8 H 10 N 2 O 3"
xref	MassAvg: "182.18"
xref	MassMono: "182.069142"
xref	Origin: "T, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01422 oxazole/oxazoline ring crosslinked residues (Thr) ! oxazole/oxazoline ring crosslinked residues (Thr)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1902. MOD:01902 L-isoleucine oxazole-4-carboxylic acid

Table 1904. Term [MOD:01902]
id	MOD:01902
name	L-isoleucine oxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-isoleucine residue and an L-serine residue to form L-cysteine oxazole-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0573]
comment	Cross-link 2.
synonym	"2-[(1S,2S)-1-amino-2-methylbutyl]-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[(1S,2S)-1-azanyl-2-methylbutyl]-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Oxazole-4-carboxylic acid (Ile-Ser)" EXACT UniProt-feature []
synonym	"L-isoleucine oxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 9 H 12 N 2 O 2"
xref	MassAvg: "180.21"
xref	MassMono: "180.089878"
xref	Origin: "I, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00910 modified L-isoleucine residue ! modified L-isoleucine residue
is_a	MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser) ! oxazole/oxazoline ring crosslinked residues (Ser)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1903. MOD:01903 L-serine oxazole-4-carboxylic acid

Table 1905. Term [MOD:01903]
id	MOD:01903
name	L-serine oxazole-4-carboxylic acid
def	"A protein modification that effectively crosslinks two L-serine residues to form serine oxazole-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0574]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-hydroxyethyl]-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[(1S)-1-azanyl-2-hydroxyethyl]-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK Oxazole-4-carboxylic acid (Ser-Ser)" EXACT UniProt-feature []
synonym	"L-serine oxazole-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-20.03"
xref	DiffFormula: "C 0 H -4 N 0 O -1"
xref	DiffMono: "-20.026215"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "S, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01421 oxazole/oxazoline ring crosslinked residues (Ser) ! oxazole/oxazoline ring crosslinked residues (Ser)
is_a	MOD:01888 didehydrogenated residue ! didehydrogenated residue

2.1904. MOD:01904 L-serine 5-methyloxazoline-4-carboxylic acid

Table 1906. Term [MOD:01904]
id	MOD:01904
name	L-serine 5-methyloxazoline-4-carboxylic acid
def	"A protein modification that effectively crosslinks an L-serine residue and an L-threonine residue to form L-serine 5-methyloxazoline-4-carboxylic acid." [PubMed:21568297, PubMed:21950656, RESID:AA0575]
comment	Cross-link 2.
synonym	"2-[(1S)-1-amino-2-hydroxyethyl]-5-methyl-1,3-oxazoline-4-carboxylic acid" EXACT RESID-alternate []
synonym	"2-[(1S)-1-amino-2-hydroxyethyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxylic acid" EXACT RESID-systematic []
synonym	"2-[(1S)-1-azanyl-2-hydroxyethyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxylic acid" EXACT RESID-alternate []
synonym	"CROSSLNK 5-methyloxazoline-4-carboxylic acid (Ser-Thr)" EXACT UniProt-feature []
synonym	"L-serine 5-methyloxazoline-4-carboxylic acid" EXACT RESID-name []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 10 N 2 O 3"
xref	MassAvg: "170.17"
xref	MassMono: "170.069142"
xref	Origin: "S, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01422 oxazole/oxazoline ring crosslinked residues (Thr) ! oxazole/oxazoline ring crosslinked residues (Thr)

2.1905. MOD:01905 5-hydroxy-3-methyl-L-proline

Table 1907. Term [MOD:01905]
id	MOD:01905
name	5-hydroxy-3-methyl-L-proline
def	"A protein modification that effectively converts a source amino acid residue to 5-hydroxy-3-methyl-L-proline." [PubMed:7592021, PubMed:8557573, RESID:AA0473]
synonym	"(2S,3S,5Xi)-5-hydroxy-3-methylpyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"5-hydroxy-3-methyl-L-proline" EXACT RESID-name []
synonym	"5-hydroxy-3-methylproline" EXACT RESID-alternate []
synonym	"5Hy3MePro" EXACT PSI-MOD-label []
synonym	"beta-methyl-delta-hydroxyproline" EXACT RESID-alternate []
synonym	"MOD_RES 5-hydroxy-3-methylproline (Ile)" EXACT UniProt-feature []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 9 N 1 O 2"
xref	MassAvg: "127.14"
xref	MassMono: "127.063329"
xref	Origin: "X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
relationship	has_functional_parent MOD:01024 monohydroxylated proline ! monohydroxylated proline

2.1906. MOD:01906 dehydromethionine

Table 1908. Term [MOD:01906]
id	MOD:01906
name	dehydromethionine
def	"A protein modification that effectively converts an L-methionine residue to dehydromethionine." [PubMed:18688235, PubMed:19775156]
synonym	"(3S)-3-carboxy-1-methylisothiazolidin-1-ium" EXACT PSI-MOD-alternate []
synonym	"L-dehydromethionine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-1.01"
xref	DiffFormula: "C 0 H -1 N 0 O 0 S 0"
xref	DiffMono: "-1.008374"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.039936"
xref	Origin: "M"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue

2.1907. MOD:01907 dehydromethionine (from L-methioninium)

Table 1909. Term [MOD:01907]
id	MOD:01907
name	dehydromethionine (from L-methioninium)
def	"A protein modification that effectively converts an L-methioninium (protonated L-methionine) residue to dehydromethionine." [PubMed:18688235, PubMed:19775156]
comment	This process accounts only for cyclizaation and not protonation. The alternative process (MOD:01906) accounts for both protonation and cyclization.
synonym	"(3S)-3-carboxy-1-methylisothiazolidin-1-ium" EXACT PSI-MOD-alternate []
synonym	"L-dehydromethionine" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.016199"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 9 N 1 O 1 S 1"
xref	MassAvg: "131.19"
xref	MassMono: "131.039936"
xref	Origin: "MOD:001464"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:00601 cyclized residue ! cyclized residue
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
relationship	derives_from MOD:01464 protonated L-methionine (L-methioninium) residue ! protonated L-methionine (L-methioninium) residue

2.1908. MOD:01908 4-sulfophenyl isothiocyanate alpha-amino derivatized residue

Table 1910. Term [MOD:01908]
id	MOD:01908
name	4-sulfophenyl isothiocyanate alpha-amino derivatized residue
def	"A protein modification that effectively converts a residue to the 4-sulfophenyl isothiocyanate adduct, alpha-amino-[(4-sulfophenyl)carbamothioyl] residue." [PubMed:14689565, PubMed:14745769, PubMed:15549660, PubMed:16526082, UniMod:261#N-term]
synonym	"4-sulfophenyl isothiocyanate" RELATED UniMod-description []
synonym	"alpha-amino-[(4-sulfophenyl)carbamothioyl] residue" EXACT PSI-MOD-alternate []
synonym	"SPITC" RELATED PSI-MS-label []
xref	DiffAvg: "215.24"
xref	DiffFormula: "C 7 H 5 N 1 O 3 S 2"
xref	DiffMono: "214.971085"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00584 4-sulfophenyl isothiocyanate derivatized residue ! 4-sulfophenyl isothiocyanate derivatized residue

2.1909. MOD:01909 6x(13)C labeled 4-sulfophenyl isothiocyanate alpha-amino derivatized residue

Table 1911. Term [MOD:01909]
id	MOD:01909
name	6x(13)C labeled 4-sulfophenyl isothiocyanate alpha-amino derivatized residue
def	"A protein modification that effectively converts a residue to the 6x(13)C labeled 4-sulfophenyl isothiocyanate adduct, alpha-amino-[(4-sulfophenyl)carbamothioyl] residue." [PubMed:11467524, PubMed:16526082, UniMod:464#N-term]
synonym	"4-sulfophenyl isothiocyanate (Heavy C13)" RELATED UniMod-description []
synonym	"SPITC:13C(6)" RELATED PSI-MS-label []
xref	DiffAvg: "220.99"
xref	DiffFormula: "(12)C 1 (13)C 6 H 5 N 1 O 3 S 2"
xref	DiffMono: "220.991214"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00880 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue ! 6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized residue

2.1910. MOD:01910 monofluorinated residue

Table 1912. Term [MOD:01910]
id	MOD:01910
name	monofluorinated residue
def	"A protein modification that effectively substitutes one hydrogen atom of a residue with one fluorine atom." [UniMod:127]
synonym	"F1Res" EXACT PSI-MOD-label []
xref	DiffAvg: "17.99"
xref	DiffFormula: "C 0 F 1 H -1 N 0 O 0"
xref	DiffMono: "17.990578"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00498 fluorinated residue ! fluorinated residue

2.1911. MOD:01911 monochlorinated residue

Table 1913. Term [MOD:01911]
id	MOD:01911
name	monochlorinated residue
def	"A protein modification that effectively substitutes one hydrogen atom of a residue with one chlorine atom." [UniMod:936]
synonym	"Cl1Res" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00753 chlorinated residue ! chlorinated residue

2.1912. MOD:01912 monobrominated residue

Table 1914. Term [MOD:01912]
id	MOD:01912
name	monobrominated residue
def	"A protein modification that effectively substitutes one hydrogen atom of a residue with one bromine atom." [UniMod:340]
synonym	"Br1Res" EXACT PSI-MOD-label []
xref	DiffAvg: "78.90"
xref	DiffFormula: "Br 1 C 0 H -1 N 0 O 0"
xref	DiffMono: "77.910512"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00754 brominated residue ! brominated residue

2.1913. MOD:01913 monochlorinated L-tryptophan

Table 1915. Term [MOD:01913]
id	MOD:01913
name	monochlorinated L-tryptophan
def	"A protein modification that effectively substitutes one hydrogen atom of an L-tryptophan residue with one chlorine atom." [PubMed:18688235]
synonym	"Cl1Trp" EXACT PSI-MOD-label []
xref	DiffAvg: "34.44"
xref	DiffFormula: "C 0 Cl 1 H -1 N 0 O 0"
xref	DiffMono: "33.961028"
xref	Formula: "C 11 Cl 1 H 9 N 2 O 1"
xref	MassAvg: "220.66"
xref	MassMono: "220.040341"
xref	Origin: "W"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:01068 halogenated tryptophan ! halogenated tryptophan
is_a	MOD:01911 monochlorinated residue ! monochlorinated residue

2.1914. MOD:01914 O5-galactosyl-L-hydroxylysine

Table 1916. Term [MOD:01914]
id	MOD:01914
name	O5-galactosyl-L-hydroxylysine
def	"A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine." [PMID:743239, PubMed:17516569, UniMod:907]
comment	Secondary to RESID:AA0028. This intermediate is rarely observed [JSG].
subset	PSI-MOD-slim
synonym	"Galactosyl hydroxylysine" RELATED UniMod-description []
synonym	"OGal5HyLys" EXACT PSI-MOD-label []
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 N 0 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "C 16 H 22 N 2 O 7"
xref	MassAvg: "354.36"
xref	MassMono: "354.142701"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00476 galactosylated residue ! galactosylated residue

2.1915. MOD:01915 N-formyl-L-alanine

Table 1917. Term [MOD:01915]
id	MOD:01915
name	N-formyl-L-alanine
def	"A protein modification that effectively converts an L-alanine residue to N-formyl-L-alanine." [PubMed:9334739, RESID:AA0576]
synonym	"(2S)-2-(formylamino)propanoic acid" EXACT RESID-systematic []
synonym	"2-formamidopropanoic acid" EXACT RESID-alternate []
synonym	"2-formamidopropionic acid" EXACT RESID-alternate []
synonym	"N-formyl-L-alanine" EXACT RESID-name []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 4 H 6 N 1 O 2"
xref	MassAvg: "100.10"
xref	MassMono: "100.039853"
xref	Origin: "A"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00409 N-formylated residue ! N-formylated residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue

2.1916. MOD:01916 O4'-(N-acetylamino)galactosyl-L-tyrosine

Table 1918. Term [MOD:01916]
id	MOD:01916
name	O4'-(N-acetylamino)galactosyl-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-(N-acetylamino)galactosyl-L-tyrosine." [PubMed:21712440, PubMed:21983924, RESID:AA0577]
synonym	"(2S)-2-amino-3-(D-2-acetamido-2-deoxygalactopyranosyloxy)phenylpropanoic acid" EXACT RESID-systematic []
synonym	"CARBOHYD O-linked (GalNAc)" EXACT UniProt-feature []
synonym	"mucin type O-glycosyltyrosine" EXACT RESID-alternate []
synonym	"O4'-(N-acetylamino)galactosyl-L-tyrosine" EXACT RESID-name []
synonym	"O4'-(N-acetylgalactosaminyl)tyrosine" EXACT RESID-alternate []
synonym	"O4'-glycosyl-L-tyrosine" EXACT RESID-alternate []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 17 H 22 N 2 O 7"
xref	MassAvg: "366.37"
xref	MassMono: "366.142701"
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00563 N-acetylaminogalactosylated residue ! N-acetylaminogalactosylated residue
is_a	MOD:01927 O-glycosyl-L-tyrosine ! O-glycosyl-L-tyrosine

2.1917. MOD:01917 N6-(L-isoaspartyl)-L-lysine (Asp)

Table 1919. Term [MOD:01917]
id	MOD:01917
name	N6-(L-isoaspartyl)-L-lysine (Asp)
def	"A protein modification that effectively crosslinks an L-aspartic acid residue and an L-lysine residue by an isopeptide bond with the formation of N6-(L-isoaspartyl)-L-lysine and the release of water." [ChEBI:21862, PubMed:11000116, PubMed:15044436, PubMed:18063798, PubMed:6503713, RESID:AA0294#ASP]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(3S)-3-amino-3-carboxypropanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"beta-(N6-lysyl)aspartyl acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl lysine isopeptide (Lys-Asn)" EXACT UniProt-feature []
synonym	"isoaspartyl N6-lysine" EXACT RESID-alternate []
synonym	"N(epsilon)-(beta-aspartyl)lysine" EXACT RESID-alternate []
synonym	"N6-(L-isoaspartyl)-L-lysine" EXACT RESID-name []
synonym	"XLNK-4Asp-N6Lys(Asp)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 10 H 15 N 3 O 3"
xref	MassAvg: "225.25"
xref	MassMono: "225.111341"
xref	Origin: "D, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01929 N6-(L-isoaspartyl)-L-lysine ! N6-(L-isoaspartyl)-L-lysine

2.1918. MOD:01918 (2S,5S)-5-hydroxylysine

Table 1920. Term [MOD:01918]
id	MOD:01918
name	(2S,5S)-5-hydroxylysine
def	"A protein modification that effectively converts an L-lysine residue to (2S,5S)-5-hydroxylysine." [PubMed:19574390, PubMed:22238144, RESID:AA0578]
subset	PSI-MOD-slim
synonym	"(2S,5S)-2,6-diamino-5-hydroxyhexanoic acid" EXACT RESID-systematic []
synonym	"(2S,5S)-5-hydroxylysine" EXACT RESID-name []
synonym	"2,6-bisazanyl-5-hydroxyhexanoic acid" EXACT RESID-alternate []
synonym	"2,6-diamino-2,3,4,6-tetradeoxyhexonic acid" EXACT RESID-alternate []
synonym	"alpha,epsilon-diamino-delta-hydroxycaproic acid" EXACT RESID-alternate []
synonym	"L-allo-delta-hydroxylysine" EXACT RESID-alternate []
synonym	"L-threo-delta-hydroxylysine" EXACT RESID-alternate []
synonym	"MOD_RES (5S)-5-hydroxylysine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 2 O 2"
xref	MassAvg: "144.17"
xref	MassMono: "144.089878"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine

2.1919. MOD:01919 (2S,3S)-3-hydroxyaspartic acid

Table 1921. Term [MOD:01919]
id	MOD:01919
name	(2S,3S)-3-hydroxyaspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to (2S,3S)-3-hydroxyaspartic acid." [ChEBI:10696, PubMed:21177872, RESID:AA0579]
subset	PSI-MOD-slim
synonym	"(2S,3S)-2-amino-3-hydroxybutanedioic acid" EXACT RESID-systematic []
synonym	"(2S,3S)-3-hydroxyaspartic acid" EXACT RESID-name []
synonym	"(3S)-3-hydroxy-L-aspartic acid" EXACT RESID-alternate []
synonym	"2-amino-3-hydroxysuccinic acid" EXACT RESID-alternate []
synonym	"2-azanyl-3-hydroxybutanedioic acid" EXACT RESID-alternate []
synonym	"3-hydroxyaspartic acid" EXACT RESID-alternate []
synonym	"L-threo-3-hydroxyaspartic acid" EXACT RESID-alternate []
synonym	"L-threo-beta-hydroxyaspartic acid" EXACT RESID-alternate []
synonym	"MOD_RES (3S)-3-hydroxyaspartate" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 5 N 1 O 4"
xref	MassAvg: "131.09"
xref	MassMono: "131.021858"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01926 3-hydroxy-L-aspartic acid ! 3-hydroxy-L-aspartic acid

2.1920. MOD:01920 3-hydroxy-L-histidine

Table 1922. Term [MOD:01920]
id	MOD:01920
name	3-hydroxy-L-histidine
def	"A protein modification that effectively converts an L-histidine residue to 3-hydroxy-L-histidine." [PubMed:21251231, RESID:AA0580]
synonym	"(2S)-2-amino-3-hydroxy-3-(1H-imidazol-4-yl)propanoic acid" EXACT RESID-systematic []
synonym	"3-hydroxy-L-histidine" EXACT RESID-name []
synonym	"MOD_RES 3-hydroxyhistidine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 7 N 3 O 2"
xref	MassAvg: "153.14"
xref	MassMono: "153.053826"
xref	Origin: "H"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00677 hydroxylated residue ! hydroxylated residue

2.1921. MOD:01921 D-aspartic acid (Asp)

Table 1923. Term [MOD:01921]
id	MOD:01921
name	D-aspartic acid (Asp)
def	"A protein modification that effectively converts an L-aspartic acid residue to D-aspartic acid." [ChEBI:48094, PubMed:9384562, RESID:AA0190#ASP]
synonym	"(2R)-2-aminobutanedioic acid" EXACT RESID-systematic []
synonym	"2-azanylbutanedioic acid" EXACT RESID-alternate []
synonym	"aminosuccinic acid" EXACT RESID-alternate []
synonym	"D-aspartic acid" EXACT RESID-name []
xref	DiffAvg: "0.00"
xref	DiffFormula: "C 0 H 0 N 0 O 0"
xref	DiffMono: "0.000000"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "D"
xref	Source: "artifactual"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01942 D-aspartic acid ! D-aspartic acid

2.1922. MOD:01922 3-methoxydehydroalanine

Table 1924. Term [MOD:01922]
id	MOD:01922
name	3-methoxydehydroalanine
def	"A protein modification that effectively converts an L-serine residue to 3-methoxydehydroalanine." [PubMed:19745839, RESID:AA0582]
synonym	"2-amino-3-methoxyprop-2-enoic acid" EXACT RESID-systematic []
synonym	"3-methoxydehydroalanine" EXACT RESID-name []
synonym	"3-methoxydidehydroalanine" EXACT RESID-alternate []
xref	DiffAvg: "12.01"
xref	DiffFormula: "C 1 H 0 N 0 O 0"
xref	DiffMono: "12.000000"
xref	Formula: "C 4 H 5 N 1 O 2"
xref	MassAvg: "99.09"
xref	MassMono: "99.032028"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
relationship	has_functional_parent MOD:00189 dehydroalanine (Ser) ! dehydroalanine (Ser)

2.1923. MOD:01923 N6-(L-aspartyl)-L-lysine

Table 1925. Term [MOD:01923]
id	MOD:01923
name	N6-(L-aspartyl)-L-lysine
def	"A protein modification that effectively crosslinks an L-aspartic acid residue and an L-lysine residue by an isopeptide bond to form N6-(L-aspartyl)-L-lysine and the release of water." [PubMed:15044436, RESID:AA0583]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(2S)-2-amino-3-carboxypropanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"alpha-(N6-lysyl)aspartyl acid" EXACT RESID-alternate []
synonym	"aspartyl N6-lysine" EXACT RESID-alternate []
synonym	"N(epsilon)-(alpha-aspartyl)lysine" EXACT RESID-alternate []
synonym	"N6-(L-aspartyl)-L-lysine" EXACT RESID-name []
synonym	"XLNK-4Asp-N6Lys(Asp)" EXACT PSI-MOD-label []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 10 H 16 N 3 O 4"
xref	MassAvg: "242.26"
xref	MassMono: "242.114081"
xref	Origin: "D, K"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1924. MOD:01924 S-octanoyl-L-cysteine

Table 1926. Term [MOD:01924]
id	MOD:01924
name	S-octanoyl-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-octanoyl-L-cysteine." [PubMed:12591875, PubMed:16342964, RESID:AA0584]
synonym	"(2S)-2-amino-3-(octanoylsulfanyl)propanoic acid" EXACT RESID-systematic []
synonym	"2-amino-3-(octanoylthio)propanoic acid" EXACT RESID-alternate []
synonym	"ACT_SITE Acyl-thioester intermediate" EXACT UniProt-feature []
synonym	"cysteine octanoate thioester" EXACT RESID-alternate []
synonym	"S-octanoyl-L-cysteine" EXACT RESID-name []
xref	DiffAvg: "126.20"
xref	DiffFormula: "C 8 H 14 N 0 O 1 S 0"
xref	DiffMono: "126.104465"
xref	Formula: "C 11 H 19 N 1 O 2 S 1"
xref	MassAvg: "229.34"
xref	MassMono: "229.113650"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00666 octanoylated residue ! octanoylated residue
is_a	MOD:00672 S-acylated residue ! S-acylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1925. MOD:01925 (2S,5R)-5-hydroxylysine

Table 1927. Term [MOD:01925]
id	MOD:01925
name	(2S,5R)-5-hydroxylysine
def	"A protein modification that effectively converts an L-lysine residue to (2S,5R)-5-hydroxylysine." [ChEBI:18040, PubMed:13375629, PubMed:15504407, PubMed:16101297, PubMed:2857489, RESID:AA0028]
subset	PSI-MOD-slim
synonym	"(2S,5R)-2,6-diamino-5-hydroxyhexanoic acid" EXACT RESID-systematic []
synonym	"(2S,5R)-5-hydroxylysine" EXACT RESID-name []
synonym	"2,6-bisazanyl-5-hydroxyhexanoic acid" EXACT RESID-alternate []
synonym	"2,6-diamino-2,3,4,6-tetradeoxyhexonic acid" EXACT RESID-alternate []
synonym	"5-hydroxylated L-lysine" EXACT PSI-MOD-alternate []
synonym	"5HyLys" EXACT PSI-MOD-label []
synonym	"alpha,epsilon-diamino-delta-hydroxycaproic acid" EXACT RESID-alternate []
synonym	"L-erythro-delta-hydroxylysine" EXACT RESID-alternate []
synonym	"MOD_RES (2S,5R)-5-hydroxylysine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 2 O 2"
xref	MassAvg: "144.17"
xref	MassMono: "144.089878"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00037 5-hydroxy-L-lysine ! 5-hydroxy-L-lysine

2.1926. MOD:01926 3-hydroxy-L-aspartic acid

Table 1928. Term [MOD:01926]
id	MOD:01926
name	3-hydroxy-L-aspartic acid
def	"A protein modification that effectively converts an L-aspartic acid residue to one of the diastereomeric 3-hydroxy-L-aspartic acid residues." [OMSSA:59, UniMod:35#D]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-hydroxybutanedioic acid" EXACT PSI-MOD-alternate []
synonym	"(2S)-3-hydroxyaspartic acid" EXACT PSI-MOD-alternate []
synonym	"3HyAsp" EXACT PSI-MOD-label []
synonym	"erythro-beta-hydroxylated L-aspartic acid" EXACT PSI-MOD-alternate []
synonym	"hydroxylationd" EXACT OMSSA-label []
synonym	"monohydroxylated aspartic acid" EXACT PSI-MOD-alternate []
synonym	"Oxidation" RELATED PSI-MS-label []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 4 H 5 N 1 O 4"
xref	MassAvg: "131.09"
xref	MassMono: "131.021858"
xref	Origin: "D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00425 monohydroxylated residue ! monohydroxylated residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue

2.1927. MOD:01927 O-glycosyl-L-tyrosine

Table 1929. Term [MOD:01927]
id	MOD:01927
name	O-glycosyl-L-tyrosine
def	"A protein modification that effectively converts an L-tyrosine residue to O4'-glycosyltyrosine." [PubMed:18688235]
subset	PSI-MOD-slim
synonym	"OGlycoTyr" EXACT PSI-MOD-label []
xref	Origin: "Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00396 O-glycosylated residue ! O-glycosylated residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1928. MOD:01928 N-(L-isoaspartyl)-glycine

Table 1930. Term [MOD:01928]
id	MOD:01928
name	N-(L-isoaspartyl)-glycine
def	"A protein modification that effectively crosslinks either an L-asparagine residue or an L-aspartic acid residue with a glycine residue by an isopeptide bond with formation of N-(L-isoaspartyl)glycine." [ChEBI:21479, PubMed:1826288, RESID:AA0126]
comment	Cross-link 2.
synonym	"(2S)-2-amino-4-(carboxymethyl)amino-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"2-amino-N4-(carboxymethyl)-butanediamic acid" EXACT RESID-alternate []
synonym	"isoaspartyl glycine" EXACT RESID-alternate []
synonym	"N-(L-isoaspartyl)-glycine" EXACT RESID-name []
synonym	"N-beta-aspartylglycine" EXACT RESID-alternate []
synonym	"N4-(carboxymethyl)-asparagine" EXACT RESID-alternate []
synonym	"XLNK-4Asp-NGly" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 7 N 2 O 3"
xref	MassAvg: "155.13"
xref	MassMono: "155.045667"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:00908 modified glycine residue ! modified glycine residue

2.1929. MOD:01929 N6-(L-isoaspartyl)-L-lysine

Table 1931. Term [MOD:01929]
id	MOD:01929
name	N6-(L-isoaspartyl)-L-lysine
def	"A protein modification that effectively crosslinks an either an L-asparagine residue or an L-aspartic acid residue with an L-lysine residue by an isopeptide bond with the formation of N6-(L-isoaspartyl)-L-lysine." [ChEBI:21862, DeltaMass:0, PubMed:11000116, PubMed:6503713, RESID:AA0294]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(3S)-3-amino-3-carboxypropanoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"beta-(N6-lysyl)aspartyl acid" EXACT RESID-alternate []
synonym	"CROSSLNK Isoaspartyl lysine isopeptide (Lys-Asn)" EXACT UniProt-feature []
synonym	"isoaspartyl N6-lysine" EXACT RESID-alternate []
synonym	"N(epsilon)-(beta-aspartyl)lysine" EXACT RESID-alternate []
synonym	"N-(beta-Aspartyl)-Lysine (Crosslink)" EXACT DeltaMass-label []
synonym	"N6-(L-isoaspartyl)-L-lysine" EXACT RESID-name []
synonym	"XLNK-4Asp-N6Lys" EXACT PSI-MOD-label []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 10 H 15 N 3 O 3"
xref	MassAvg: "225.25"
xref	MassMono: "225.111341"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00688 isopeptide crosslinked residues ! isopeptide crosslinked residues
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1930. MOD:01930 D-aspartic acid (Asn)

Table 1932. Term [MOD:01930]
id	MOD:01930
name	D-aspartic acid (Asn)
def	"A protein modification that effectively converts an L-asparagine residue to D-aspartic acid." [ChEBI:48094, PubMed:9384562, RESID:AA0190#ASN]
synonym	"(2R)-2-aminobutanedioic acid" EXACT RESID-systematic []
synonym	"2-azanylbutanedioic acid" EXACT RESID-alternate []
synonym	"aminosuccinic acid" EXACT RESID-alternate []
synonym	"D-aspartic acid" EXACT RESID-name []
xref	DiffAvg: "0.98"
xref	DiffFormula: "C 0 H -1 N -1 O 1"
xref	DiffMono: "0.984016"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "N"
xref	Source: "artifactual"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01942 D-aspartic acid ! D-aspartic acid

2.1931. MOD:01931 N6-phospho-L-lysine

Table 1933. Term [MOD:01931]
id	MOD:01931
name	N6-phospho-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-phospho-L-lysine." [PubMed:20144148, RESID:AA0585]
synonym	"(2S)-2-amino-6-(phosphonoamino)hexanoic acid" EXACT RESID-systematic []
synonym	"(2S)-2-azanyl-6-(phosphonoamino)hexanoic acid" EXACT RESID-alternate []
synonym	"6-phospholysine" EXACT RESID-alternate []
synonym	"N(6)-phosphonolysine" EXACT RESID-alternate []
synonym	"N(epsilon)-phospholysine" EXACT RESID-alternate []
synonym	"N(epsilon)-phosphonolysine" EXACT RESID-alternate []
synonym	"N(epsilon)-phosphonyllysine" EXACT RESID-alternate []
synonym	"N(epsilon)-phosphoryllysine" EXACT RESID-alternate []
synonym	"N6-phospho-L-lysine" EXACT RESID-name []
xref	DiffAvg: "79.98"
xref	DiffFormula: "C 0 H 1 N 0 O 3 P 1"
xref	DiffMono: "79.966331"
xref	Formula: "C 6 H 13 N 2 O 4 P 1"
xref	MassAvg: "208.15"
xref	MassMono: "208.061294"
xref	Origin: "K"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01456 N-phosphorylated residue ! N-phosphorylated residue

2.1932. MOD:01932 L-lysinonorleucine

Table 1934. Term [MOD:01932]
id	MOD:01932
name	L-lysinonorleucine
def	"A protein modification that effectively cross-links two lysine residues with a carbon-nitrogen bond to form L-lysinonorleucine.." [PubMed:5117030, PubMed:5817620, PubMed:5879466, PubMed:6030254, RESID:AA0586]
comment	Cross-link 2.
synonym	"(2S)-2-amino-6-([(5S)-5-amino-5-carboxypentyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"(2S,2’S)-6,6'-iminobis(2-aminohexanoic acid)" EXACT RESID-alternate []
synonym	"6-(N6-L-lysino)-L-norleucine" EXACT RESID-alternate []
synonym	"L-lysinonorleucine" EXACT RESID-name []
synonym	"lysinonorleucine" EXACT RESID-alternate []
synonym	"lysinorleucine [misspelling]" EXACT RESID-alternate []
synonym	"lysylnorleucine" EXACT RESID-alternate []
synonym	"N6-[(5S)-5-amino-5-carboxypentyl]-L-lysine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 12 H 21 N 3 O 2"
xref	MassAvg: "239.32"
xref	MassMono: "239.163377"
xref	Origin: "K, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia

2.1933. MOD:01933 desmosine

Table 1935. Term [MOD:01933]
id	MOD:01933
name	desmosine
def	"A protein modification that effectively cross-links four L-lysine residues to form desmosine." [ChEBI:37629, PubMed:13941623, PubMed:14109938, PubMed:14109939, PubMed:5839176, RESID:AA0587]
comment	Cross-link 4.
synonym	"4-[(4S)-4-amino-4-carboxybutyl]-1-[(5S)-5-amino-5-carboxypentyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]pyridinium" EXACT RESID-systematic []
synonym	"6-[4-(4-amino-4-carboxybutyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinio]norleucine" EXACT RESID-alternate []
synonym	"desmosine" EXACT RESID-name []
xref	DiffAvg: "-58.15"
xref	DiffFormula: "C 0 H -16 N -3 O 0"
xref	DiffMono: "-58.134971"
xref	FormalCharge: "1+"
xref	Formula: "C 24 H 32 N 5 O 4"
xref	MassAvg: "454.55"
xref	MassMono: "454.244881"
xref	Origin: "K, K, K, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01425 pyridinyl ring crosslinked residues ! pyridinyl ring crosslinked residues

2.1934. MOD:01934 isodesmosine

Table 1936. Term [MOD:01934]
id	MOD:01934
name	isodesmosine
def	"A protein modification that effectively cross-links four L-lysine residues to form isodesmosine." [ChEBI:37629, PubMed:13941623, PubMed:14109938, PubMed:14109939, PubMed:5839176, RESID:AA0588]
comment	Cross-link 4.
synonym	"2-[(4S)-4-amino-4-carboxybutyl]-1-[(5S)-5-amino-5-carboxypentyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]pyridinium" EXACT RESID-systematic []
synonym	"6-[2-(4-amino-4-carboxybutyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinio]norleucine" EXACT RESID-alternate []
synonym	"isodesmosine" EXACT RESID-name []
xref	DiffAvg: "-58.15"
xref	DiffFormula: "C 0 H -16 N -3 O 0"
xref	DiffMono: "-58.134971"
xref	FormalCharge: "1+"
xref	Formula: "C 24 H 32 N 5 O 4"
xref	MassAvg: "454.55"
xref	MassMono: "454.244881"
xref	Origin: "K, K, K, K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue
is_a	MOD:01425 pyridinyl ring crosslinked residues ! pyridinyl ring crosslinked residues

2.1935. MOD:01935 O-glucosyl-L-hydroxylysine

Table 1937. Term [MOD:01935]
id	MOD:01935
name	O-glucosyl-L-hydroxylysine
def	"modification from RESID" [PubMed:22045808, RESID:AA0589]
synonym	"(D-glucopyranosyl)oxy-L-lysine" EXACT RESID-systematic []
synonym	"O-glucosyl-L-hydroxylysine" EXACT RESID-name []
xref	DiffAvg: "178.14"
xref	DiffFormula: "C 6 H 10 N 0 O 6"
xref	DiffMono: "178.047738"
xref	Formula: "C 12 H 22 N 2 O 7"
xref	MassAvg: "306.32"
xref	MassMono: "306.142701"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01047 monohydroxylated lysine ! monohydroxylated lysine

2.1936. MOD:01936 N6-oleoyl-L-lysine

Table 1938. Term [MOD:01936]
id	MOD:01936
name	N6-oleoyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-oleoyl-L-lysine." [PubMed:20942504, RESID:AA0590]
synonym	"(2S)-2-amino-6-([(9Z)-octadec-9-enoyl]amino)hexanoic acid" EXACT RESID-systematic []
synonym	"N6-[(9Z)-1-oxo-9-octadecenyl]lysine" EXACT RESID-alternate []
synonym	"N6-oleoyl-L-lysine" EXACT RESID-name []
xref	DiffAvg: "264.45"
xref	DiffFormula: "C 18 H 32 N 0 O 1"
xref	DiffMono: "264.245316"
xref	Formula: "C 24 H 44 N 2 O 2"
xref	MassAvg: "392.63"
xref	MassMono: "392.340279"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1937. MOD:01937 N-palmitoyl-L-methionine

Table 1939. Term [MOD:01937]
id	MOD:01937
name	N-palmitoyl-L-methionine
def	"A protein modification that effectively converts an L-methionine residue to N-palmitoyl-L-methionine." [PubMed:20942504, RESID:AA0591]
synonym	"(2S)-2-(hexadecanoylamino)-4-(methylsulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"2-(hexadecanamido)-4-(methylsulfanyl)butanoic acid" EXACT RESID-alternate []
synonym	"LIPID N-palmitoyl methionine" EXACT UniProt-feature []
synonym	"N-(1-oxohexadecyl)methionine" EXACT RESID-alternate []
synonym	"N-palmitoyl-L-methionine" EXACT RESID-name []
xref	DiffAvg: "238.41"
xref	DiffFormula: "C 16 H 30 N 0 O 1 S 0"
xref	DiffMono: "238.229666"
xref	Formula: "C 21 H 40 N 1 O 2 S 1"
xref	MassAvg: "370.62"
xref	MassMono: "370.277976"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00913 modified L-methionine residue ! modified L-methionine residue
is_a	MOD:01685 alpha-amino palmitoylated residue ! alpha-amino palmitoylated residue

2.1938. MOD:01938 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid (Asn)

Table 1940. Term [MOD:01938]
id	MOD:01938
name	2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid (Asn)
def	"A protein modification that crosslinks an asparagine and the following cysteine residue with the formation of (2-aminosuccinimidyl)-3-sulfanylpropanoic acid and the release of ammonia." [RESID:AA0592#ASN]
comment	Cross-link 2.
synonym	"(2R)-2-[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid" EXACT RESID-name []
synonym	"aspartimide cysteine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0 S 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 7 H 8 N 2 O 3 S 1"
xref	MassAvg: "200.21"
xref	MassMono: "200.025563"
xref	Origin: "C, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01945 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid ! 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid

2.1939. MOD:01939 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid (Asp)

Table 1941. Term [MOD:01939]
id	MOD:01939
name	2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid (Asp)
def	"A protein modification that crosslinks an aspartic acid and the following cysteine residue with the formation of (2-aminosuccinimidyl)-3-sulfanylpropanoic acid and the loss of a water molecule." [RESID:AA0592#ASP]
comment	Cross-link 2.
synonym	"(2R)-2-[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]-3-sulfanylpropanoic acid" EXACT RESID-systematic []
synonym	"2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid" EXACT RESID-name []
synonym	"aspartimide cysteine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 8 N 2 O 3 S 1"
xref	MassAvg: "200.21"
xref	MassMono: "200.025563"
xref	Origin: "C, D"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01945 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid ! 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid

2.1940. MOD:01940 2-(2-aminosuccinimidyl)pentanedioic acid (Asn)

Table 1942. Term [MOD:01940]
id	MOD:01940
name	2-(2-aminosuccinimidyl)pentanedioic acid (Asn)
def	"A protein modification that crosslinks an asparagine and the following glutamic acid residue with the formation of (2-aminosuccinimidyl)pentanedioic acid and the release of ammonia." [RESID:AA0593#ASN]
comment	Cross-link 2.
synonym	"(4S)-4-[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"2-(2-aminosuccinimidyl)pentanedioic acid" EXACT RESID-name []
synonym	"aspartimide glutamic acid" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 9 H 10 N 2 O 5"
xref	MassAvg: "226.19"
xref	MassMono: "226.058971"
xref	Origin: "E, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01946 2-(2-aminosuccinimidyl)pentanedioic acid ! 2-(2-aminosuccinimidyl)pentanedioic acid

2.1941. MOD:01941 2-(2-aminosuccinimidyl)pentanedioic acid (Asp)

Table 1943. Term [MOD:01941]
id	MOD:01941
name	2-(2-aminosuccinimidyl)pentanedioic acid (Asp)
def	"A protein modification that crosslinks an aspartic acid and the following glycine residue with the formation of (2-aminosuccinimidyl)pentanedioic acid and the loss of a water molecule." [RESID:AA0593#ASP]
comment	Cross-link 2.
synonym	"(4S)-4-[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"2-(2-aminosuccinimidyl)pentanedioic acid" EXACT RESID-name []
synonym	"aspartimide glutamic acid" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 9 H 10 N 2 O 5"
xref	MassAvg: "226.19"
xref	MassMono: "226.058971"
xref	Origin: "D, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:01946 2-(2-aminosuccinimidyl)pentanedioic acid ! 2-(2-aminosuccinimidyl)pentanedioic acid

2.1942. MOD:01942 D-aspartic acid

Table 1944. Term [MOD:01942]
id	MOD:01942
name	D-aspartic acid
def	"A protein modification that effectively converts a source amino acid residue to D-aspartic acid." [ChEBI:48094, PubMed:9384562, RESID:AA0190]
synonym	"(2R)-2-aminobutanedioic acid" EXACT RESID-systematic []
synonym	"2-azanylbutanedioic acid" EXACT RESID-alternate []
synonym	"aminosuccinic acid" EXACT RESID-alternate []
synonym	"D-aspartic acid" EXACT RESID-name []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 4 H 5 N 1 O 3"
xref	MassAvg: "115.09"
xref	MassMono: "115.026943"
xref	Origin: "X"
xref	Source: "artifactual"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1943. MOD:01943 pyrrolidione ring crosslinked residues

Table 1945. Term [MOD:01943]
id	MOD:01943
name	pyrrolidione ring crosslinked residues
def	"A protein modification that crosslinks two adjacent residues by formation of a pyrrolidione ring." [PubMed:18688235]
is_a	MOD:00033 crosslinked residues ! crosslinked residues

2.1944. MOD:01944 2-aminosuccinimide ring crosslinked residues

Table 1946. Term [MOD:01944]
id	MOD:01944
name	2-aminosuccinimide ring crosslinked residues
def	"A protein modification that forms (2-aminosuccinimidyl)acetic acid by crosslinking either an aspartic acid residue or an asparagine residue with the following residue." [PubMed:18688235]
comment	Cross-link 2; this cross-link is formed by the condensation of an aspartic acid residue or an asparagine residue with the alpha-amido of the following residue.
subset	PSI-MOD-slim
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues

2.1945. MOD:01945 2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid

Table 1947. Term [MOD:01945]
id	MOD:01945
name	2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acid
def	"A protein modification that forms (2-aminosuccinimidyl)-3-sulfanylpropanoic acid by crosslinking either an aspartic acid residue or an asparagine residue with the following cysteine residue." [PubMed:18688235]
comment	Cross-link 2; this cross-link is formed by the condensation of an aspartic acid residue or an asparagine residue with the alpha-amido of the following residue.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "C, X"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:01944 2-aminosuccinimide ring crosslinked residues ! 2-aminosuccinimide ring crosslinked residues

2.1946. MOD:01946 2-(2-aminosuccinimidyl)pentanedioic acid

Table 1948. Term [MOD:01946]
id	MOD:01946
name	2-(2-aminosuccinimidyl)pentanedioic acid
def	"A protein modification that forms (2-aminosuccinimidyl)pentanedioicacid by crosslinking either an aspartic acid residue or an asparagine residue with the following glutamic acid\n residue." [PubMed:18688235]
comment	Cross-link 2; this cross-link is formed by the condensation of an aspartic acid residue or an asparagine residue with the alpha-amido of the following residue.
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 6 H 6 N 2 O 3"
xref	MassAvg: "154.13"
xref	MassMono: "154.037842"
xref	Origin: "E, X"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:01944 2-aminosuccinimide ring crosslinked residues ! 2-aminosuccinimide ring crosslinked residues

2.1947. MOD:01947 O-(L-isoaspartyl)-L-threonine (cross-link)

Table 1949. Term [MOD:01947]
id	MOD:01947
name	O-(L-isoaspartyl)-L-threonine (cross-link)
def	"A protein modification that effectively cross-links an L-threonine residue and an L-aspartic acid residue with an ester bond to form O-(L-isoaspartyl)-L-threonine." [PubMed:17157318, PubMed:8706862, RESID:AA0525#TDX]
comment	Cross-link 2.
synonym	"(2S)-2-amino-4-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-3-amino-3-carboxypropanoyl]oxy)propanoic acid" EXACT RESID-alternate []
synonym	"CROSSLNK isoaspartyl threonine ester (Thr-Asp)" EXACT UniProt-feature []
synonym	"O(beta)-(beta-aspartyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoaspartyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoaspartyl)-threonine" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1"
xref	DiffMono: "-18.010565"
xref	Formula: "C 8 H 10 N 2 O 4"
xref	MassAvg: "198.18"
xref	MassMono: "198.064057"
xref	Origin: "D, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01978 O-(L-isoaspartyl)-L-threonine ! O-(L-isoaspartyl)-L-threonine

2.1948. MOD:01948 labionin

Table 1950. Term [MOD:01948]
id	MOD:01948
name	labionin
def	"A protein modification that effectively cross-links an L-cysteine residue and two L-serine residues by a thioether bond and a carbon-carbon bond to form labionin." [PubMed:20082397, RESID:AA0594]
comment	Cross-link 3.
synonym	"(2S,4S)-2,4-diamino-2-[([(2R)-2-amino-2-carboxyethyl]sulfanyl)methyl]pentanedioic acid" EXACT RESID-systematic []
synonym	"(2S,4S,8R)-2,4,8-triamino-4-carboxy-6-thianonanedioic acid" EXACT RESID-alternate []
synonym	"(2S,4S,8R)-labionin" EXACT RESID-alternate []
synonym	"labionin" EXACT RESID-name []
xref	DiffAvg: "-36.03"
xref	DiffFormula: "C 0 H -4 N 0 O -2 S 0"
xref	DiffMono: "-36.021129"
xref	Formula: "C 9 H 11 N 3 O 3 S 1"
xref	MassAvg: "241.26"
xref	MassMono: "241.052112"
xref	Origin: "C, S, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues

2.1949. MOD:01949 coelenterazine

Table 1951. Term [MOD:01949]
id	MOD:01949
name	coelenterazine
def	"A protein modification that effectively cross-links a phenylalanine and two tyrosine residues to form coelenterazine." [ChEBI:2311, PubMed:10830969, PubMed:11572972, PubMed:19833098, RESID:AA0595]
comment	Cross-link 3.
synonym	"8-benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one" EXACT RESID-systematic []
synonym	"coelenterazine" EXACT RESID-name []
synonym	"Oplophorus luciferin" EXACT RESID-alternate []
xref	DiffAvg: "-50.06"
xref	DiffFormula: "C -1 H -6 N 0 O -2"
xref	DiffMono: "-50.036779"
xref	Formula: "C 26 H 21 N 3 O 3"
xref	MassAvg: "423.47"
xref	MassMono: "423.158292"
xref	Origin: "F, Y, Y"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:00033 crosslinked residues ! crosslinked residues
is_a	MOD:00914 modified L-phenylalanine residue ! modified L-phenylalanine residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue

2.1950. MOD:01950 L-isoglutamyl histamine

Table 1952. Term [MOD:01950]
id	MOD:01950
name	L-isoglutamyl histamine
def	"A protein modification that effectively converts an L-glutamine residue to L-isoglutamyl histamine." [PubMed:23022564, RESID:AA0596]
synonym	"(2S)-2-amino-5-([2-(1H-imidazol-5-yl)ethyl]amino)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(gamma-glutamyl)histamine" EXACT RESID-alternate []
synonym	"L-isoglutamyl histamine" EXACT RESID-name []
xref	DiffAvg: "94.12"
xref	DiffFormula: "C 5 H 6 N 2 O 0"
xref	DiffMono: "94.053098"
xref	Formula: "C 10 H 14 N 4 O 2"
xref	MassAvg: "222.25"
xref	MassMono: "222.111676"
xref	Origin: "Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.1951. MOD:01951 O-(L-isoglutamyl)-L-serine (Gln-Ser)

Table 1953. Term [MOD:01951]
id	MOD:01951
name	O-(L-isoglutamyl)-L-serine (Gln-Ser)
def	"A protein modification that effectively crosslinks an L-glutamine residue and an L-serine residue by an ester bond and releasing ammonia to form O-(L-isoglutamyl)-L-serine." [PubMed:17051152, RESID:AA0597#QSX]
comment	Cross-link 2.
synonym	"(2S)-2-amino-5-[(2S)-2-amino-2-carboxyethoxy]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"O(beta)-(gamma-glutamyl)serine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-serine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)-serine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 8 H 10 N 2 O 4"
xref	MassAvg: "198.18"
xref	MassMono: "198.064057"
xref	Origin: "Q, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:00946 crosslinked residues with loss of ammonia ! crosslinked residues with loss of ammonia
is_a	MOD:01977 O-(L-isoglutamyl)-L-serine ! O-(L-isoglutamyl)-L-serine

2.1952. MOD:01952 O-(L-isoglutamyl)-L-threonine (cross-link)

Table 1954. Term [MOD:01952]
id	MOD:01952
name	O-(L-isoglutamyl)-L-threonine (cross-link)
def	"A protein modification that effectively cross-links an L-threonine residue and an L-glutamine residue with an ester bond releasing ammonia to form O-(L-isoglutamyl)-L-threonine." [PubMed:17051152, RESID:AA0536#TQX]
comment	Cross-link 2.
synonym	"(2S)-2-amino-5-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-4-amino-4-carboxybutanoyl]oxy)-propanoic acid" EXACT RESID-alternate []
synonym	"5-(threon-O3-yl)glutamate" EXACT RESID-alternate []
synonym	"O(beta)-(gamma-glutamyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)threonine" EXACT RESID-alternate []
xref	DiffAvg: "-17.03"
xref	DiffFormula: "C 0 H -3 N -1 O 0"
xref	DiffMono: "-17.026549"
xref	Formula: "C 9 H 12 N 2 O 4"
xref	MassAvg: "212.20"
xref	MassMono: "212.079707"
xref	Origin: "Q, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue
is_a	MOD:01979 O-(L-isoglutamyl)-L-threonine ! O-(L-isoglutamyl)-L-threonine

2.1953. MOD:01953 tetrakis-L-cysteinyl tetrairon octanitrosyl

Table 1955. Term [MOD:01953]
id	MOD:01953
name	tetrakis-L-cysteinyl tetrairon octanitrosyl
def	"A protein modification that effectively converts four L-cysteine residues and a four-iron cluster to tetrakis-L-cysteinyl tetrairon octanitrosyl." [PubMed:21182249, RESID:AA0599]
comment	Cross-link 4.
xref	DiffAvg: "459.40"
xref	DiffFormula: "C 0 Fe 4 H -4 N 8 O 8 S 0"
xref	DiffMono: "459.692359"
xref	Formula: "C 12 Fe 4 H 16 N 12 O 12 S 4"
xref	MassAvg: "871.95"
xref	MassMono: "871.729098"
xref	Origin: "C, C, C, C"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00738 iron containing modified residue ! iron containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1954. MOD:01954 dehydroalanine (Sec)

Table 1956. Term [MOD:01954]
id	MOD:01954
name	dehydroalanine (Sec)
def	"A protein modification that effectively converts an L-selenocysteine residue to dehydroalanine." [ChEBI:17123, PubMed:10220322, PubMed:12781460, PubMed:1547888, PubMed:1815586, PubMed:20805503, PubMed:21420488, PubMed:22031445, PubMed:2914619, PubMed:7947813, PubMed:8239649, RESID:AA0181]
synonym	"2,3-didehydroalanine" EXACT RESID-alternate []
synonym	"2-aminoacrylic acid" EXACT RESID-alternate []
synonym	"2-aminopropenoic acid" EXACT RESID-systematic []
synonym	"4-methylidene-imidazole-5-one (MIO) active site" EXACT RESID-alternate []
synonym	"anhydroserine" EXACT RESID-alternate []
synonym	"dehydroalanine" EXACT RESID-name []
synonym	"Dha" EXACT RESID-alternate []
xref	DiffAvg: "-80.99"
xref	DiffFormula: "C 0 H -2 N 0 O 0 Se -1"
xref	DiffMono: "-81.932171"
xref	Formula: "C 3 H 3 N 1 O 1"
xref	MassAvg: "69.06"
xref	MassMono: "69.021464"
xref	Origin: "U"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01158 modified L-selenocysteine residue ! modified L-selenocysteine residue
is_a	MOD:01168 dehydroalanine ! dehydroalanine

2.1955. MOD:01955 L-alaninato bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese pentoxide

Table 1957. Term [MOD:01955]
id	MOD:01955
name	L-alaninato bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese pentoxide
def	"modification from RESID" [PubMed:21499260, RESID:AA0600]
comment	Cross-link 7.
synonym	"4Mn-Ca-5O cluster" EXACT RESID-alternate []
synonym	"L-alaninato bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese pentoxide" EXACT RESID-name []
synonym	"mu2-alaninato-1kappaO(1),3kappaO(1')-mu2-aspartato-1kappaO(4),5kappaO(4')-mu2-aspartato-2kappaO(4),3kappaO(4')-mu2-glutamato-3kappaO(5),4kappaO(5')-mu2-glutamato-4kappaO(5),5kappaO(5')-mu-glutamato-2kappaO(5)-mu-histidino-2kappaN(tau)-mu4-oxido-1:2:4:5kappa(4)O-tri-mu3-oxido-1:2:3kappa(3)O;1:3:4kappa(3)O;2:3:4kappa(3)O;mu-oxido-4:5kappa(2)O-calciumtetramanganese" EXACT RESID-systematic []
synonym	"photosystem II catalytic cluster" EXACT RESID-alternate []
xref	DiffAvg: "333.78"
xref	DiffFormula: "C 0 Ca 1 H -6 Mn 4 N 0 O 5"
xref	DiffMono: "333.642394"
xref	Formula: "C 32 Ca 1 H 38 Mn 4 N 9 O 23"
xref	MassAvg: "1176.53"
xref	MassMono: "1175.922825"
xref	Origin: "A, D, D, E, E, E, H"
xref	Source: "natural"
xref	TermSpec: "C-term"
is_a	MOD:00740 manganese containing modified residue ! manganese containing modified residue
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:00904 modified L-aspartic acid residue ! modified L-aspartic acid residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue
is_a	MOD:00909 modified L-histidine residue ! modified L-histidine residue
is_a	MOD:01482 calcium containing modified residue ! calcium containing modified residue

2.1956. MOD:01956 (3R)-3-hydroxy-L-arginine

Table 1958. Term [MOD:01956]
id	MOD:01956
name	(3R)-3-hydroxy-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to (3R)-3-hydroxy-L-arginine." [PubMed:10094780, PubMed:23103944, PubMed:786730, RESID:AA0601]
synonym	"(2S,3R)-2-amino-5-[(diaminomethylidene)amino]-3-hydroxypentanoic acid" EXACT RESID-systematic []
synonym	"(3R)-3-hydroxy-L-arginine" EXACT RESID-name []
synonym	"2-amino-5-(carbamimidamido)-3-hydroxypentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-[(aminoiminomethyl)amino]-3-hydroxypentanoic acid [tautomer]" EXACT RESID-alternate []
synonym	"2-amino-5-guanidino-3-hydroxypentanoic acid" EXACT RESID-alternate []
synonym	"beta-hydroxyarginine" EXACT RESID-alternate []
synonym	"C(beta)-hydroxyarginine" EXACT RESID-alternate []
synonym	"MOD_RES (3R)-3-hydroxyarginine" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 6 H 12 N 4 O 2"
xref	MassAvg: "172.19"
xref	MassMono: "172.096026"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00682 hydroxylated arginine ! hydroxylated arginine

2.1957. MOD:01957 2-hydroxyproline

Table 1959. Term [MOD:01957]
id	MOD:01957
name	2-hydroxyproline
def	"A protein modification that effectively converts an L-proline residue to 2-hydroxyproline." [PubMed:23385463, RESID:AA0602]
synonym	"(2R)-2-hydroxypyrrolidine-2-carboxylic acid" EXACT RESID-systematic []
synonym	"2-hydroxyproline" EXACT RESID-name []
synonym	"2-oxidanylpyrrolidine-2-carboxylic acid" EXACT RESID-alternate []
synonym	"alpha-hydroxyproline" EXACT RESID-alternate []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 7 N 1 O 2"
xref	MassAvg: "113.12"
xref	MassMono: "113.047678"
xref	Origin: "P"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01024 monohydroxylated proline ! monohydroxylated proline

2.1958. MOD:01958 bis-L-cysteinyl bisglutathion-S-yl diiron disulfide

Table 1960. Term [MOD:01958]
id	MOD:01958
name	bis-L-cysteinyl bisglutathion-S-yl diiron disulfide
def	"A protein modification that effectively converts four L-cysteine residues and a two-iron two-sulfur cluster to bis-L-cysteinyl bisglutathion-S-yl diiron disulfide." [PubMed:17121859, RESID:AA0603]
comment	Cross-link 2.
synonym	"bis-L-cysteinyl bisglutathion-S-yl diiron disulfide" EXACT RESID-name []
synonym	"di-mu-sulfido-bis(cysteinato)-1kappaS,2kappaS-bis(glutathionato)-1kappaS,2kappaS-diiron" EXACT RESID-systematic []
synonym	"mitochondrial glutaredoxin 2 dimer iron-sulfur cluster" EXACT RESID-alternate []
synonym	"plant glutaredoxin C1 dimer iron-sulfur cluster" EXACT RESID-alternate []
xref	DiffAvg: "786.42"
xref	DiffFormula: "C 20 Fe 2 H 30 N 6 O 12 S 4"
xref	DiffMono: "785.950329"
xref	Formula: "C 26 Fe 2 H 40 N 8 O 14 S 6"
xref	MassAvg: "992.70"
xref	MassMono: "991.968699"
xref	Origin: "C, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1959. MOD:01959 tris-L-cysteinyl L-glutamato tetrairon tetrasulfide

Table 1961. Term [MOD:01959]
id	MOD:01959
name	tris-L-cysteinyl L-glutamato tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-glutamic acid and a four-iron four-sulfur cluster to tris-L-cysteinyl L-glutamato tetrairon tetrasulfide." [PubMed:21167158, RESID:AA0604]
comment	Cross-link 4.
synonym	"tris-L-cysteinyl L-glutamato tetrairon tetrasulfide" EXACT RESID-name []
synonym	"tris-mu3-sulfido-tris(cysteinato)-1kappaS,2kappaS,3kappaS-glutamato-4kappaO(5),4kappaO(5')-tetrairon" EXACT RESID-systematic []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.596734"
xref	Formula: "C 14 Fe 4 H 18 N 4 O 6 S 7"
xref	MassAvg: "786.12"
xref	MassMono: "785.666881"
xref	Origin: "C, C, C, E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1960. MOD:01960 tris-L-cysteinyl L-glutamin-O6-yl tetrairon tetrasulfide

Table 1962. Term [MOD:01960]
id	MOD:01960
name	tris-L-cysteinyl L-glutamin-O6-yl tetrairon tetrasulfide
def	"A protein modification that effectively converts three L-cysteine residues, an L-glutamine residue and a four-iron four-sulfur cluster to tris-L-cysteinyl L-glutamin-O6-yl tetrairon tetrasulfide." [PubMed:11796730, RESID:AA0605]
comment	Cross-link 4.
synonym	"METAL Iron-sulfur (4Fe-4S)" EXACT UniProt-feature []
synonym	"tris-L-cysteinyl L-glutamin-O6-yl tetrairon tetrasulfide" EXACT RESID-name []
synonym	"tris-mu3-sulfido-tris(cysteinato)-1kappaS,2kappaS,3kappaS-glutaminato-4kappaN(5)-tetrairon" EXACT RESID-systematic []
xref	DiffAvg: "347.59"
xref	DiffFormula: "C 0 Fe 4 H -4 N 0 O 0 S 4"
xref	DiffMono: "347.596734"
xref	Formula: "C 14 Fe 4 H 19 N 5 O 5 S 7"
xref	MassAvg: "785.14"
xref	MassMono: "784.682866"
xref	Origin: "C, C, C, Q"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00739 iron-sulfur cluster containing modification ! iron-sulfur cluster containing modification
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue
is_a	MOD:00907 modified L-glutamine residue ! modified L-glutamine residue

2.1961. MOD:01961 O-(L-isoglutamyl)-L-threonine (THR)

Table 1963. Term [MOD:01961]
id	MOD:01961
name	O-(L-isoglutamyl)-L-threonine (THR)
def	"OBSOLETE because redundant and identical to MOD:01785. Remap to MOD:01785." [PubMed:16618936, PubMed:17051152, PubMed:17687277, PubMed:18555071, RESID:AA0536#THR]
synonym	"(2S)-2-amino-5-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-4-amino-4-carboxybutanoyl]oxy)-propanoic acid" EXACT RESID-alternate []
synonym	"5-(threon-O3-yl)glutamate" EXACT RESID-alternate []
synonym	"O(beta)-(gamma-glutamyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)threonine" EXACT RESID-alternate []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 9 H 14 N 2 O 5"
xref	MassAvg: "230.22"
xref	MassMono: "230.090272"
xref	Origin: "T"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1962. MOD:01962 N4-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-asparagine

Table 1964. Term [MOD:01962]
id	MOD:01962
name	N4-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-asparagine
def	"A protein modification that effectively converts an L-asparagine residue to N4-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-asparagine." [PubMed:12186869, PubMed:19236052, RESID:AA0606]
synonym	"(2S)-2-amino-4-[(2,4-diacetylamino-2,4,6-trideoxy-beta-D-glucopyranosyl)amino]-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"DABA" EXACT RESID-alternate []
synonym	"DATDH" EXACT RESID-alternate []
synonym	"DiNAcBac" EXACT RESID-alternate []
synonym	"N4-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-asparagine" EXACT RESID-name []
synonym	"N4-[2,4-bis(acetylamino)-2,4,6-trideoxy-beta-D-glucopyranosyl]-L-asparagine" EXACT RESID-alternate []
synonym	"N4-[N,N-diacetylbacillosaminyl]asparagine" EXACT RESID-alternate []
synonym	"N4-[N2,N4-diacetylbacillosaminyl]asparagine" EXACT RESID-alternate []
xref	DiffAvg: "228.25"
xref	DiffFormula: "C 10 H 16 N 2 O 4"
xref	DiffMono: "228.111007"
xref	Formula: "C 14 H 22 N 4 O 6"
xref	MassAvg: "342.35"
xref	MassMono: "342.153934"
xref	Origin: "N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00160 N4-glycosyl-L-asparagine ! N4-glycosyl-L-asparagine

2.1963. MOD:01963 O-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-serine

Table 1965. Term [MOD:01963]
id	MOD:01963
name	O-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-serine." [PubMed:23030644, RESID:AA0607]
synonym	"(2S)-2-amino-4-[(2,4-diacetamido-2,4,6-trideoxy-beta-D-glucopyranosyl)oxy]propanoic acid" EXACT RESID-systematic []
synonym	"DABA" EXACT RESID-alternate []
synonym	"DATDH" EXACT RESID-alternate []
synonym	"DiNAcBac" EXACT RESID-alternate []
synonym	"O-(2,4-diacetamido-2,4,6-trideoxy-D-glucosyl)-L-serine" EXACT RESID-name []
synonym	"O-[2,4-bis(acetylamino)-2,4,6-trideoxy-beta-D-glucopyranosyl]-L-serine" EXACT RESID-alternate []
synonym	"O-[N,N-diacetylbacillosaminyl]serine" EXACT RESID-alternate []
synonym	"O-[N2,N4-diacetylbacillosaminyl]serine" EXACT RESID-alternate []
xref	DiffAvg: "228.25"
xref	DiffFormula: "C 10 H 16 N 2 O 4"
xref	DiffMono: "228.111007"
xref	Formula: "C 13 H 21 N 3 O 6"
xref	MassAvg: "315.33"
xref	MassMono: "315.143035"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.1964. MOD:01964 O-(2-acetamido-4-glyceramido-2,4,6-trideoxy-D-glucosyl)-L-serine

Table 1966. Term [MOD:01964]
id	MOD:01964
name	O-(2-acetamido-4-glyceramido-2,4,6-trideoxy-D-glucosyl)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O-(2-acetamido-4-glyceramido-2,4,6-trideoxy-D-glucosyl)-L-serine." [PubMed:17804791, RESID:AA0608]
synonym	"(2S)-2-amino-3-[(2-acetamido-4-glycerylamino-2,4,6-trideoxy-D-glucopyranosyl)oxy]propanoic acid" EXACT RESID-systematic []
synonym	"GATDH" EXACT RESID-alternate []
synonym	"O-(2-acetamido-4-glyceramido-2,4,6-trideoxy-D-glucopyranosyl)-L-serine" EXACT RESID-alternate []
synonym	"O-(2-acetamido-4-glyceramido-2,4,6-trideoxy-D-glucosyl)-L-serine" EXACT RESID-name []
synonym	"O-(N2-acetyl-N4-glycerylbacillosaminyl)-L-serine" EXACT RESID-alternate []
xref	DiffAvg: "274.27"
xref	DiffFormula: "C 11 H 18 N 2 O 6"
xref	DiffMono: "274.116486"
xref	Formula: "C 14 H 23 N 3 O 8"
xref	MassAvg: "361.35"
xref	MassMono: "361.148515"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00002 O-glycosyl-L-serine ! O-glycosyl-L-serine

2.1965. MOD:01965 2xC(13),3x(2)H labeled N6-acetyl-L-lysine

Table 1967. Term [MOD:01965]
id	MOD:01965
name	2xC(13),3x(2)H labeled N6-acetyl-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to 2xC(13),3x(2)H labeled N6-acetyl-L-lysine." [PubMed:18688235]
synonym	"Acetate labeling reagent (K) (heavy form, +5amu)" EXACT PSI-MOD-alternate []
synonym	"COFRADIC heavy acetyl 13C2 2H3" EXACT PSI-MOD-alternate []
xref	DiffAvg: "47.04"
xref	DiffFormula: "(13)C 2 (1)H -1 (2)H 3 O 1"
xref	DiffMono: "47.036105"
xref	Formula: "(12)C 6 (13)C 2 (1)H 11 (2)H 3 N 2 O 2"
xref	MassAvg: "175.13"
xref	MassMono: "175.131068"
xref	Origin: "K"
xref	Source: "artifact"
xref	TermSpec: "none"
is_a	MOD:00064 N6-acetyl-L-lysine ! N6-acetyl-L-lysine
is_a	MOD:01428 (13)C isotope tagged reagent ! (13)C isotope tagged reagent
is_a	MOD:01431 (2)H deuterium tagged reagent ! (2)H deuterium tagged reagent

2.1966. MOD:01966 L-methionine ®-sulfoxide

Table 1968. Term [MOD:01966]
id	MOD:01966
name	L-methionine ®-sulfoxide
def	"OBSOLETE because redundant and identical to MOD:00720. Remap to MOD:00720." [ChEBI:45764, PubMed:21406390, PubMed:22116028, PubMed:23911929, RESID:AA0581]
synonym	"(2S)-2-amino-4-[®-methylsulfinyl]butanoic acid" EXACT RESID-systematic []
synonym	"L-methionine ®-S-oxide" EXACT RESID-alternate []
synonym	"L-methionine ®-sulfoxide" EXACT RESID-name []
synonym	"MOD_RES Methionine ®-sulfoxide" EXACT UniProt-feature []
xref	DiffAvg: "16.00"
xref	DiffFormula: "C 0 H 0 N 0 O 1 S 0"
xref	DiffMono: "15.994915"
xref	Formula: "C 5 H 9 N 1 O 2 S 1"
xref	MassAvg: "147.19"
xref	MassMono: "147.035400"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_obsolete	true

2.1967. MOD:01967 omega-N-(N-acetylamino)glucosyl-L-arginine

Table 1969. Term [MOD:01967]
id	MOD:01967
name	omega-N-(N-acetylamino)glucosyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to omega-N-(N-acetylamino)glucosyl-L-arginine." [PubMed:23955153, RESID:AA0609]
synonym	"(2S)-2-amino-5-[(amino[(2-N-acetylamino-2-deoxy-D-glucopyranosyl)amino]methylidene)amino]pentanoic acid" EXACT RESID-systematic []
synonym	"N(omega)-(2-acetamido-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"N(omega)-(2-acetylamino-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"N(omega)-(2-N-acetylaminoglucosyl)arginine" EXACT RESID-alternate []
synonym	"NG-(2-acetamido-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"NG-(2-acetylamino-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"NG-(2-N-acetylaminoglucosyl)arginine" EXACT RESID-alternate []
synonym	"omega-N-(2-acetamido-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"omega-N-(2-acetylamino-2-deoxy-D-glucopyranosyl)-L-arginine" EXACT RESID-alternate []
synonym	"omega-N-(2-N-acetylaminoglucosyl)arginine" EXACT RESID-alternate []
synonym	"omega-N-(N-acetylamino)glucosyl-L-arginine" EXACT RESID-name []
xref	DiffAvg: "203.19"
xref	DiffFormula: "C 8 H 13 N 1 O 5"
xref	DiffMono: "203.079373"
xref	Formula: "C 14 H 25 N 5 O 6"
xref	MassAvg: "359.38"
xref	MassMono: "359.180484"
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00448 N-acetylaminoglucosylated residue ! N-acetylaminoglucosylated residue
is_a	MOD:01980 omega-N-glycosyl-L-arginine ! omega-N-glycosyl-L-arginine

2.1968. MOD:01968 (2R,3R,2’R)-3-methyllanthionine

Table 1970. Term [MOD:01968]
id	MOD:01968
name	(2R,3R,2’R)-3-methyllanthionine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form (2R,3R,2’R)-3-methyllanthionine." [PubMed:23314913, RESID:AA0610]
comment	Cross-link 2.
synonym	"(2R,3R)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanoic acid" EXACT RESID-systematic []
synonym	"(2R,3R,2’R)-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid" EXACT RESID-alternate []
synonym	"(2R,3R,2’R)-3-methyllanthionine" EXACT RESID-name []
synonym	"(2R,3R,6R)-2,6-diamino-3-methyl-4-thiaheptanedioic acid" EXACT RESID-alternate []
synonym	"(2R,3R,6R)-3-methyllanthionine" EXACT RESID-alternate []
synonym	"2-azanyl-3-[(2-azanyl-2-carboxyethyl)sulfanyl]butanoic acid" EXACT RESID-alternate []
synonym	"3-methyl-L,L-lanthionine" EXACT RESID-alternate []
synonym	"cysteine-3-L-butyrine thioether" EXACT RESID-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 10 N 2 O 2 S 1"
xref	MassAvg: "186.23"
xref	MassMono: "186.046299"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:01981 3-methyllanthionine ! 3-methyllanthionine

2.1969. MOD:01969 S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine

Table 1971. Term [MOD:01969]
id	MOD:01969
name	S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine." [PubMed:9398217, RESID:AA0611]
synonym	"(2S)-2-amino-5-([(2R)-1-([2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-2-oxoethyl]amino)-1-oxo-3-sulfanylpropan-2-yl]amino)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"ACT_SITE S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine intermediate" EXACT UniProt-feature []
synonym	"S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine" EXACT RESID-name []
synonym	"S-(glutathion-1-yl)-L-cysteine" EXACT RESID-alternate []
xref	DiffAvg: "289.31"
xref	DiffFormula: "C 10 H 15 N 3 O 5 S 1"
xref	DiffMono: "289.073242"
xref	Formula: "C 13 H 20 N 4 O 6 S 2"
xref	MassAvg: "392.44"
xref	MassMono: "392.082426"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1970. MOD:01970 5-glutamyl glutamic acid

Table 1972. Term [MOD:01970]
id	MOD:01970
name	5-glutamyl glutamic acid
def	"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl glutamic acid, forming an isopeptide bond with a free glutamic acid." [PubMed:10747868, PubMed:15525938, PubMed:1680872, PubMed:23434852, RESID:AA0612, UniMod:450]
synonym	"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)pentanedioic acid" EXACT RESID-systematic []
synonym	"(2S)-2-[(4S)-4-amino-4-carboxybutanamido]pentanedioic acid" EXACT RESID-alternate []
synonym	"2-([4-azanyl-4-carboxybutanoyl]azanyl)pentanedioic acid" EXACT RESID-alternate []
synonym	"5-glutamyl glutamic acid" EXACT RESID-name []
synonym	"gamma-glutamylglutamate" EXACT RESID-alternate []
synonym	"Glu" RELATED UniMod-interim []
synonym	"isoglutamyl glutamic acid" EXACT RESID-alternate []
synonym	"isoglutamyl monoglutamic acid" EXACT RESID-alternate []
synonym	"MOD_RES 5-glutamyl glutamate" EXACT UniProt-feature []
synonym	"monoglutamyl" RELATED UniMod-description []
synonym	"N alpha -(gamma-Glutamyl)-Glu" EXACT DeltaMass-label []
synonym	"N-(gamma-L-glutamyl)-L-glutamic acid" EXACT RESID-alternate []
xref	DiffAvg: "129.12"
xref	DiffFormula: "C 5 H 7 N 1 O 3"
xref	DiffMono: "129.042593"
xref	Formula: "C 10 H 14 N 2 O 6"
xref	MassAvg: "258.23"
xref	MassMono: "258.085186"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00207 L-isoglutamyl-polyglutamic acid ! L-isoglutamyl-polyglutamic acid

2.1971. MOD:01971 5-glutamyl N2-ornithine

Table 1973. Term [MOD:01971]
id	MOD:01971
name	5-glutamyl N2-ornithine
def	"A protein modification that effectively converts an L-glutamic acid residue to N2-ornithine." [PubMed:23434852, RESID:AA0613]
synonym	"(2S)-5-amino-2-([(4S)-4-amino-4-carboxybutanoyl]amino)pentanoic acid" EXACT RESID-alternate []
synonym	"(2S)-5-amino-2-[(4S)-4-amino-4-carboxybutanamido]pentanoic acid" EXACT RESID-systematic []
synonym	"4-amino-5-[(4-amino-1-carboxy-butyl)amino]-5-ketovaleric acid" EXACT RESID-alternate []
synonym	"4-amino-5-[(4-amino-1-carboxy-butyl)amino]-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"5-glutamyl N2-ornithine" EXACT RESID-name []
synonym	"gamma-glutamylornithine" EXACT RESID-alternate []
synonym	"MOD_RES 5-glutamyl N2-ornithine" EXACT UniProt-feature []
synonym	"N2-(gamma-glutamyl)ornithine" EXACT RESID-alternate []
synonym	"N2-(L-isoglutamyl)-L-ornithine" EXACT RESID-alternate []
xref	DiffAvg: "114.15"
xref	DiffFormula: "C 5 H 10 N 2 O 1"
xref	DiffMono: "114.079313"
xref	Formula: "C 10 H 17 N 3 O 4"
xref	MassAvg: "243.26"
xref	MassMono: "243.121906"
xref	Origin: "E"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00674 amidated residue ! amidated residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1972. MOD:01972 5-glutamyl coenzyme A thioester

Table 1974. Term [MOD:01972]
id	MOD:01972
name	5-glutamyl coenzyme A thioester
def	"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl coenzyme A thioester." [PubMed:16253988, PubMed:20977214, PubMed:7915164, RESID:AA0614]
synonym	"(2S)-2-amino-5-(2-[([3-([(2R)-2-hydroxy-3,3-dimethyl-4-([3'-phospho-adenosyl-5'-diphosphoryl]-oxy)-butanoyl]-amino)-propanoyl]-amino)-ethyl]-sulfanyl)-5-oxopentanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-5-([2-(3-[(2R)-2-hydroxy-3,3-dimethyl-4-([3'-phospho-adenosyl-5'-diphosphoryl]-oxy)-butanamido]-propanamido)-ethyl]-sulfanyl)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"5-glutamyl 4-[(3'-phospho-adenosyl-5'-diphosphoryl)oxy]pantetheine thioester" EXACT RESID-alternate []
synonym	"5-glutamyl coenzyme A thioester" EXACT RESID-name []
synonym	"5-glutamyl coenzyme A thioester intermediate" EXACT UniProt-feature []
xref	DiffAvg: "749.52"
xref	DiffFormula: "C 21 H 34 N 7 O 15 P 3 S 1"
xref	DiffMono: "749.104644"
xref	Formula: "C 26 H 41 N 8 O 18 P 3 S 1"
xref	MassAvg: "878.63"
xref	MassMono: "878.147237"
xref	Origin: "E"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00860 sulfur containing modified residue ! sulfur containing modified residue
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:00906 modified L-glutamic acid residue ! modified L-glutamic acid residue

2.1973. MOD:01973 N6-(3-phosphoglyceryl)-L-lysine

Table 1975. Term [MOD:01973]
id	MOD:01973
name	N6-(3-phosphoglyceryl)-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-(3-phosphoglyceryl)-L-lysine." [PubMed:23908237, RESID:AA0615]
synonym	"(2S)-2-amino-6-([(2R)-2-hydroxy-3-(phosphonooxy)propanoyl]amino)hexanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-6-[(2R)-2-hydroxy-3-(phosphonooxy)propanamido]hexanoic acid" EXACT RESID-systematic []
synonym	"3-phosphoglyceryl-lysine" EXACT RESID-alternate []
synonym	"N6-(3-phosphoglyceryl)-L-lysine" EXACT RESID-name []
xref	DiffAvg: "168.04"
xref	DiffFormula: "C 3 H 5 N 0 O 6 P 1"
xref	DiffMono: "167.982375"
xref	Formula: "C 9 H 17 N 2 O 7 P 1"
xref	MassAvg: "296.22"
xref	MassMono: "296.077338"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00861 phosphorus containing modified residue ! phosphorus containing modified residue
is_a	MOD:01875 N6-acylated L-lysine ! N6-acylated L-lysine

2.1974. MOD:01974 S-methyl-L-methionine

Table 1976. Term [MOD:01974]
id	MOD:01974
name	S-methyl-L-methionine
def	"A protein modification that effectively converts an L-methionine residue to S-methyl-L-methionine." [ChEBI:17728, PubMed:23532849, RESID:AA0616]
synonym	"(2S)-2-amino-4-(dimethylsulfonio)butanoate" EXACT RESID-alternate []
synonym	"(3S)-(3-amino-3-carboxypropyl)dimethylsulfanium" EXACT RESID-systematic []
synonym	"[(3S)-3-amino-3-carboxypropyl](dimethyl)sulfonium" EXACT RESID-alternate []
synonym	"S-methyl-L-methionine" EXACT RESID-name []
synonym	"S-methylmethionine" EXACT RESID-alternate []
synonym	"S-methylmethioninium" EXACT RESID-alternate []
synonym	"vitamin U" EXACT RESID-alternate []
xref	DiffAvg: "15.03"
xref	DiffFormula: "C 1 H 3 N 0 O 0 S 0"
xref	DiffMono: "15.022927"
xref	FormalCharge: "1+"
xref	Formula: "C 6 H 12 N 1 O 1 S 1"
xref	MassAvg: "146.23"
xref	MassMono: "146.063411"
xref	Origin: "M"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00716 methylated methionine ! methylated methionine

2.1975. MOD:01975 S-poly(3-hydroxybutyrate)-L-cysteine

Table 1977. Term [MOD:01975]
id	MOD:01975
name	S-poly(3-hydroxybutyrate)-L-cysteine
def	"A protein modification that effectively converts an L-cysteine residue to S-(poly-3-hydroxybutyrate)-L-cysteine." [PubMed:19711985, PubMed:9888824, RESID:AA0617]
synonym	"(alpha)-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-(omega)-[(3R)-3-hydroxybutanoyl]-poly([(3R)-3-methyl-1-oxopropane-1,3-diyl]oxy)" EXACT RESID-systematic []
synonym	"S-poly(3-hydroxybutanoate)cysteine" EXACT RESID-alternate []
synonym	"S-poly(3-hydroxybutanoic acid)cysteine" EXACT RESID-alternate []
synonym	"S-poly(3-hydroxybutyrate)-L-cysteine" EXACT RESID-name []
synonym	"S-poly(3-hydroxybutyrate)cysteine" EXACT RESID-alternate []
synonym	"S-poly(3-hydroxybutyric acid)cysteine" EXACT RESID-alternate []
synonym	"S-poly(beta-hydroxybutyrate)cysteine" EXACT RESID-alternate []
synonym	"S-poly[®-3-hydroxybutyrate]cysteine" EXACT RESID-alternate []
xref	DiffAvg: "172.18"
xref	DiffFormula: "C 8 H 12 N 0 O 4 S 0"
xref	DiffMono: "172.073559"
xref	Formula: "C 11 H 17 N 1 O 5 S 1"
xref	MassAvg: "275.32"
xref	MassMono: "275.082744"
xref	Origin: "C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00672 S-acylated residue ! S-acylated residue
is_a	MOD:00905 modified L-cysteine residue ! modified L-cysteine residue

2.1976. MOD:01976 O3-(poly-3-hydroxybutyrate)-L-serine

Table 1978. Term [MOD:01976]
id	MOD:01976
name	O3-(poly-3-hydroxybutyrate)-L-serine
def	"A protein modification that effectively converts an L-serine residue to O3-(poly-3-hydroxybutyrate)-L-serine." [PubMed:17659252, PubMed:20004640, RESID:AA0618]
subset	PSI-MOD-slim
synonym	"(2S)-2-amino-3-[([(3R)-3-hydroxybutanoyl]oxy)-poly([(3R)-3-methyl-1-oxopropane-1,3-diyl]oxy)]propanoic acid" EXACT RESID-systematic []
synonym	"O3-(poly-3-hydroxybutyrate)-L-serine" EXACT RESID-name []
synonym	"O3-poly(3-hydroxybutanoate)serine" EXACT RESID-alternate []
synonym	"O3-poly(3-hydroxybutanoic acid)serine" EXACT RESID-alternate []
synonym	"O3-poly(3-hydroxybutyrate)serine" EXACT RESID-alternate []
synonym	"O3-poly(3-hydroxybutyric acid)serine" EXACT RESID-alternate []
synonym	"O3-poly(beta-hydroxybutyrate)serine" EXACT RESID-alternate []
synonym	"O3-poly[®-3-hydroxybutyrate]serine" EXACT RESID-alternate []
xref	DiffAvg: "172.18"
xref	DiffFormula: "C 8 H 12 N 0 O 4"
xref	DiffMono: "172.073559"
xref	Formula: "C 11 H 17 N 1 O 6"
xref	MassAvg: "259.26"
xref	MassMono: "259.105587"
xref	Origin: "S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00671 O-acylated residue ! O-acylated residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1977. MOD:01977 O-(L-isoglutamyl)-L-serine

Table 1979. Term [MOD:01977]
id	MOD:01977
name	O-(L-isoglutamyl)-L-serine
def	"A protein modification that effectively crosslinks either an L-glutamine residue or an L-glutamic acid residue with an L-serine residue by an ester bond to form O-(L-isoglutamyl)-L-serine." [PubMed:17051152, RESID:AA0597]
comment	Cross-link 2.
synonym	"(2S)-2-amino-5-[(2S)-2-amino-2-carboxyethoxy]-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"O(beta)-(gamma-glutamyl)serine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-serine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)-serine" EXACT RESID-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 8 H 10 N 2 O 4"
xref	MassAvg: "198.18"
xref	MassMono: "198.064057"
xref	Origin: "S, X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00885 ester crosslinked residues ! ester crosslinked residues
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue

2.1978. MOD:01978 O-(L-isoaspartyl)-L-threonine

Table 1980. Term [MOD:01978]
id	MOD:01978
name	O-(L-isoaspartyl)-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-(L-isoaspartyl)-L-threonine, using either free L-asparagine and releasing ammonia or using a peptidyl L-aspartic acid residue and releasing water." [PubMed:8706862, RESID:AA0525]
comment	This is a threonine active intermediate and not an ester cross-link of peptides [JSG].
synonym	"(2S)-2-amino-4-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-3-amino-3-carboxypropanoyl]oxy)propanoic acid" EXACT RESID-alternate []
synonym	"O(beta)-(beta-aspartyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoaspartyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoaspartyl)-threonine" EXACT RESID-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 8 H 12 N 2 O 5"
xref	MassAvg: "216.19"
xref	MassMono: "216.074621"
xref	Origin: "T, X"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1979. MOD:01979 O-(L-isoglutamyl)-L-threonine

Table 1981. Term [MOD:01979]
id	MOD:01979
name	O-(L-isoglutamyl)-L-threonine
def	"A protein modification that effectively converts an L-threonine residue to O-(L-isoglutamyl)-L-threonine, using free L-glutamine and releasing ammonia, or using a peptidyl L-glutamine and releasing ammonia." [PubMed:8706862, RESID:AA0536]
comment	This is not an ester cross-link of peptides [JSG].
synonym	"(2S)-2-amino-5-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-5-oxopentanoic acid" EXACT RESID-systematic []
synonym	"(2S,3R)-2-amino-3-([(4S)-4-amino-4-carboxybutanoyl]oxy)-propanoic acid" EXACT RESID-alternate []
synonym	"5-(threon-O3-yl)glutamate" EXACT RESID-alternate []
synonym	"O(beta)-(gamma-glutamyl)threonine" EXACT RESID-alternate []
synonym	"O-(L-isoglutamyl)-L-threonine" EXACT RESID-name []
synonym	"O3-(isoglutamyl)threonine" EXACT RESID-alternate []
xref	DiffAvg: "none"
xref	DiffFormula: "none"
xref	DiffMono: "none"
xref	Formula: "C 9 H 14 N 2 O 5"
xref	MassAvg: "230.22"
xref	MassMono: "230.090272"
xref	Origin: "T, X"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:00859 modified residue that can arise from different natural residues ! modified residue that can arise from different natural residues
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue

2.1980. MOD:01980 omega-N-glycosyl-L-arginine

Table 1982. Term [MOD:01980]
id	MOD:01980
name	omega-N-glycosyl-L-arginine
def	"A protein modification that effectively converts an L-arginine residue to N4-glycosyl-arginine." [PubMed:15279557, PubMed:8521968, PubMed:9536051, RESID:AA0327, UniMod:41#R]
synonym	"(2S)-2-amino-5-(beta-D-glucopyranosyl[imino(methylamino)methyl]amino)pentanoic acid" EXACT RESID-systematic []
synonym	"Hex" RELATED PSI-MS-label []
synonym	"Hexose" RELATED UniMod-description []
synonym	"NG-beta-D-glucosylarginine" EXACT RESID-alternate []
synonym	"omega-N-(beta-D-glucosyl)-L-arginine" EXACT RESID-alternate []
synonym	"omega-N-glucosyl-L-arginine" EXACT RESID-name []
synonym	"omega-N-glycosyl-L-arginine" EXACT RESID-alternate []
xref	Origin: "R"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00006 N-glycosylated residue ! N-glycosylated residue
is_a	MOD:00902 modified L-arginine residue ! modified L-arginine residue

2.1981. MOD:01981 3-methyllanthionine

Table 1983. Term [MOD:01981]
id	MOD:01981
name	3-methyllanthionine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form 3-methyllanthionine with unresolved stereospecificity." [PubMed:18688235]
comment	Cross-link 2.
synonym	"2,6-diamino-3-methyl-4-thiaheptanedioic acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-3-([2-amino-2-carboxyethyl]sulfanyl)butanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid" EXACT PSI-MOD-alternate []
synonym	"2-azanyl-3-[(2-azanyl-2-carboxyethyl)sulfanyl]butanoic acid" EXACT PSI-MOD-alternate []
synonym	"3-methyllanthionine" EXACT PSI-MOD-alternate []
synonym	"cysteine-3-L-butyrine thioether" EXACT PSI-MOD-alternate []
xref	DiffAvg: "-18.02"
xref	DiffFormula: "C 0 H -2 N 0 O -1 S 0"
xref	DiffMono: "-18.010565"
xref	Formula: "C 7 H 10 N 2 O 2 S 1"
xref	MassAvg: "186.23"
xref	MassMono: "186.046299"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:00954 crosslinked residues with loss of water ! crosslinked residues with loss of water
is_a	MOD:01993 beta-carbon thioether crosslinked residues ! beta-carbon thioether crosslinked residues

2.1982. MOD:01982 N,N,N-trimethylglycine

Table 1984. Term [MOD:01982]
id	MOD:01982
name	N,N,N-trimethylglycine
def	"modification from RESID" [ChEBI:17750, PubMed:23818633, PubMed:23978223, RESID:AA0619]
subset	PSI-MOD-slim
synonym	"(trimethylammonio)ethanoic acid" EXACT RESID-alternate []
synonym	"1-carboxy-N,N,N-trimethylmethanazanium" EXACT RESID-alternate []
synonym	"2-trimethylammonioacetate" EXACT RESID-alternate []
synonym	"betaine" EXACT RESID-alternate []
synonym	"carboxy-N,N,N-trimethylmethanaminium" EXACT RESID-systematic []
synonym	"carboxymethyl-trimethylazanium" EXACT RESID-alternate []
synonym	"glycine betaine" EXACT RESID-alternate []
synonym	"MOD_RES N,N,N-trimethylglycine" EXACT UniProt-feature []
synonym	"N,N,N-trimethylglycine cation" EXACT RESID-alternate []
synonym	"N,N,N-trimethylglycinium" EXACT RESID-alternate []
synonym	"N2Me3+Gly" EXACT PSI-MOD-label []
xref	DiffAvg: "43.09"
xref	DiffFormula: "C 3 H 7 N 0 O 0"
xref	DiffMono: "43.054775"
xref	Formula: "C 5 H 11 N 1 O 1"
xref	MassAvg: "101.15"
xref	MassMono: "101.084064"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00714 methylated glycine ! methylated glycine
is_a	MOD:01698 alpha-amino trimethylated protonated-residue ! alpha-amino trimethylated protonated-residue

2.1983. MOD:01983 N,N-dimethylglycine

Table 1985. Term [MOD:01983]
id	MOD:01983
name	N,N-dimethylglycine
def	"A protein modification that effectively converts a glycine residue to N,N-dimethyllglycine." [ChEBI:17724, PubMed:23818633, PubMed:23978223, RESID:AA0620]
synonym	"(dimethylamino)ethanoic acid" EXACT RESID-systematic []
synonym	"1-carboxy-N,N-dimethylaminomethane" EXACT RESID-alternate []
synonym	"2-(dimethylamino)acetic acid" EXACT RESID-alternate []
synonym	"MOD_RES N,N-dimethylglycine" EXACT UniProt-feature []
synonym	"vitamin B16" EXACT RESID-alternate []
xref	DiffAvg: "28.05"
xref	DiffFormula: "C 2 H 4 N 0 O 0"
xref	DiffMono: "28.031300"
xref	Formula: "C 4 H 8 N 1 O 1"
xref	MassAvg: "86.11"
xref	MassMono: "86.060589"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00714 methylated glycine ! methylated glycine
is_a	MOD:01686 alpha-amino dimethylated residue ! alpha-amino dimethylated residue

2.1984. MOD:01984 2-(L-cystein-S-yl)-L-alanine

Table 1986. Term [MOD:01984]
id	MOD:01984
name	2-(L-cystein-S-yl)-L-alanine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-alanine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-alanine." [PubMed:21526839, RESID:AA0621]
comment	Cross-link 2.
synonym	"(2R)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"(2R,5R)-2,5-diamino-5-methyl-4-thiahexanedioic acid" EXACT RESID-alternate []
synonym	"alpha-(L-cystein-S-yl)-L-alanine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 2 S 1"
xref	MassAvg: "172.20"
xref	MassMono: "172.030649"
xref	Origin: "A, C"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00901 modified L-alanine residue ! modified L-alanine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1985. MOD:01985 2-(L-cystein-S-yl)-D-asparagine

Table 1987. Term [MOD:01985]
id	MOD:01985
name	2-(L-cystein-S-yl)-D-asparagine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-asparagine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-asparagine." [PubMed:21786372, RESID:AA0622]
comment	Cross-link 2.
synonym	"(2S)-2,4-diamino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-4-oxobutanoic acid" EXACT RESID-systematic []
synonym	"alpha-(L-cystein-S-yl)-D-asparagine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 7 H 9 N 3 O 3 S 1"
xref	MassAvg: "215.23"
xref	MassMono: "215.036462"
xref	Origin: "C, N"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00903 modified L-asparagine residue ! modified L-asparagine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1986. MOD:01986 2-(L-cystein-S-yl)-L-serine

Table 1988. Term [MOD:01986]
id	MOD:01986
name	2-(L-cystein-S-yl)-L-serine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-serine." [PubMed:21526839, RESID:AA0623]
comment	Cross-link 2.
synonym	"(2R)-2-amino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-hydroxypropanoic acid" EXACT RESID-systematic []
synonym	"(2R,5R)-2,5-diamino-5-carboxy-6-hydroxy-4-thiahexanoic acid" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 3 S 1"
xref	MassAvg: "188.20"
xref	MassMono: "188.025563"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1987. MOD:01987 2-(L-cystein-S-yl)-D-serine

Table 1989. Term [MOD:01987]
id	MOD:01987
name	2-(L-cystein-S-yl)-D-serine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-serine." [PubMed:21786372, RESID:AA0624]
comment	Cross-link 2.
synonym	"(2R,5S)-2,5-diamino-5-carboxy-6-hydroxy-4-thiahexanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-hydroxypropanoic acid" EXACT RESID-systematic []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 6 H 8 N 2 O 3 S 1"
xref	MassAvg: "188.20"
xref	MassMono: "188.025563"
xref	Origin: "C, S"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00916 modified L-serine residue ! modified L-serine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1988. MOD:01988 2-(L-cystein-S-yl)-L-threonine

Table 1990. Term [MOD:01988]
id	MOD:01988
name	2-(L-cystein-S-yl)-L-threonine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-threonine." [PubMed:21526839, RESID:AA0625]
comment	Cross-link 2.
synonym	"(2R,3R)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-hydroxybutanoic acid" EXACT RESID-systematic []
synonym	"(2R,5R,6R)-2,5-diamino-5-carboxy-6-hydroxy-4-thiaheptanoic acid" EXACT RESID-alternate []
synonym	"alpha-(L-cystein-S-yl)-L-threonine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 7 H 10 N 2 O 3 S 1"
xref	MassAvg: "202.23"
xref	MassMono: "202.041213"
xref	Origin: "C, T"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00917 modified L-threonine residue ! modified L-threonine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1989. MOD:01989 2-(L-cystein-S-yl)-D-tyrosine

Table 1991. Term [MOD:01989]
id	MOD:01989
name	2-(L-cystein-S-yl)-D-tyrosine
def	"A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-tyrosine." [PubMed:21526839, RESID:AA0626]
comment	Cross-link 2.
synonym	"(2R,5S)-2,5-diamino-5-carboxyl-6-(hydroxyphenyl)-4-thiahexanoic acid" EXACT RESID-alternate []
synonym	"(2S)-2-amino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-(4-hydroxyphenyl)propanoic acid" EXACT RESID-systematic []
synonym	"alpha-(L-cystein-S-yl)-D-tyrosine" EXACT RESID-alternate []
xref	DiffAvg: "-2.02"
xref	DiffFormula: "C 0 H -2 N 0 O 0 S 0"
xref	DiffMono: "-2.015650"
xref	Formula: "C 12 H 12 N 2 O 3 S 1"
xref	MassAvg: "264.30"
xref	MassMono: "264.056863"
xref	Origin: "C, Y"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00664 stereoisomerized residue ! stereoisomerized residue
is_a	MOD:00919 modified L-tyrosine residue ! modified L-tyrosine residue
is_a	MOD:01992 alpha-carbon thioether crosslinked residues ! alpha-carbon thioether crosslinked residues

2.1990. MOD:01990 protonated glycine (glycinium) residue

Table 1992. Term [MOD:01990]
id	MOD:01990
name	protonated glycine (glycinium) residue
def	"A protein modification that effectively converts a glycine residue to a glycinium (protonated glycine)." [ChEBI:64723, PubMed:18688235]
subset	PSI-MOD-slim
xref	DiffAvg: "1.01"
xref	DiffFormula: "C 0 H 1 N 0 O 0"
xref	DiffMono: "1.007276"
xref	FormalCharge: "1+"
xref	Formula: "C 2 H 5 N 1 O 1"
xref	MassAvg: "59.07"
xref	MassMono: "59.036565"
xref	Origin: "G"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:00908 modified glycine residue ! modified glycine residue
is_a	MOD:01700 alpha-amino protonated residue ! alpha-amino protonated residue

2.1991. MOD:01991 N,N,N-trimethylglycine (from glycinium)

Table 1993. Term [MOD:01991]
id	MOD:01991
name	N,N,N-trimethylglycine (from glycinium)
def	"A protein modification that effectively converts a glycinium (protonated glycine) residue to an N,N,N-trimethylglycine." [ChEBI:17750, PubMed:23818633, PubMed:23978223, RESID:AA0619]
comment	For amino acids residues, amine trimethylation can effectively only be accomplished with an aminium, protonated primary amino, group. This process accounts only for trimethylation and not protonation. The alternative N2Me3+Gly process (MOD:01982) accounts for both protonation and trimethylation.
subset	PSI-MOD-slim
synonym	"N2Me3Gly" EXACT PSI-MOD-label []
xref	DiffAvg: "42.08"
xref	DiffFormula: "C 3 H 6 N 0 O 0"
xref	DiffMono: "42.046402"
xref	FormalCharge: "1+"
xref	Formula: "C 5 H 11 N 1 O 1"
xref	MassAvg: "101.15"
xref	MassMono: "101.083515"
xref	Origin: "MOD:01990"
xref	Source: "natural"
xref	TermSpec: "N-term"
is_a	MOD:01687 alpha-amino trimethylated residue ! alpha-amino trimethylated residue
relationship	derives_from MOD:01990 protonated glycine (glycinium) residue ! protonated glycine (glycinium) residue

2.1992. MOD:01992 alpha-carbon thioether crosslinked residues

Table 1994. Term [MOD:01992]
id	MOD:01992
name	alpha-carbon thioether crosslinked residues
def	"A protein modification that crosslinks two residues by formation of a thioether bond between a cysteine thiol and the alpha-carbon of another amino acid residue." [PubMed:18688235]
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues

2.1993. MOD:01993 beta-carbon thioether crosslinked residues

Table 1995. Term [MOD:01993]
id	MOD:01993
name	beta-carbon thioether crosslinked residues
def	"A protein modification that crosslinks two residues by formation of a thioether bond between a cysteine thiol and the beta-carbon of another amino acid residue." [PubMed:18688235]
comment	These are typical lanthionine-like crosslinks.
is_a	MOD:00687 thioether crosslinked residues ! thioether crosslinked residues

2.1994. MOD:01994 N1'-formyl-L-tryptophan

Table 1996. Term [MOD:01994]
id	MOD:01994
name	N1'-formyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N1'-formyl-L-tryptophan." [PubMed:18688235]
comment	This modifications has not been reported as commonly encountered [JSG].
synonym	"N1’FoTrp" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 12 H 10 N 2 O 2"
xref	MassAvg: "214.22"
xref	MassMono: "214.074228"
xref	Origin: "W"
xref	Source: "hypothetical"
xref	TermSpec: "none"
is_a	MOD:01106 N-formyl-L-tryptophan ! N-formyl-L-tryptophan

2.1995. MOD:01995 N2-formyl-L-tryptophan

Table 1997. Term [MOD:01995]
id	MOD:01995
name	N2-formyl-L-tryptophan
def	"A protein modification that effectively converts an L-tryptophan residue to N2-formyl-L-tryptophan." [PubMed:18688235]
comment	This modifications has not been reported as commonly encountered [JSG].
synonym	"N2FoTrp" EXACT PSI-MOD-label []
xref	DiffAvg: "28.01"
xref	DiffFormula: "C 1 H 0 N 0 O 1"
xref	DiffMono: "27.994915"
xref	Formula: "C 12 H 11 N 2 O 2"
xref	MassAvg: "215.23"
xref	MassMono: "215.082053"
xref	Origin: "W"
xref	Source: "hypothetical"
xref	TermSpec: "N-term"
is_a	MOD:01106 N-formyl-L-tryptophan ! N-formyl-L-tryptophan

2.1996. MOD:01996 butanoylated residue

Table 1998. Term [MOD:01996]
id	MOD:01996
name	butanoylated residue
def	"A protein modification that effectively replaces a hydrogen atom with an butanoyl group." [PubMed:18688235]
comment	Amino hydrogens are replaced to produce amides; hydroxyl hydrogens are replaced to produce esters; and hydrosulfanyl (thiol) hydrogens are replaced to produce sulfanyl esters (thiol esters).
synonym	"ButRes" EXACT PSI-MOD-label []
synonym	"Butyryl" RELATED UniMod-interim []
synonym	"butyrylation" EXACT PSI-MOD-alternate []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:00649 acylated residue ! acylated residue

2.1997. MOD:01997 N-butanoylated residue

Table 1999. Term [MOD:01997]
id	MOD:01997
name	N-butanoylated residue
def	"A protein modification that effectively replaces a residue amino or imino hydrogen with a butanoyl group." [PubMed:18688235]
synonym	"N-butanoyl" EXACT PSI-MOD-alternate []
synonym	"N-butanoylation" EXACT PSI-MOD-alternate []
synonym	"N-butyryl" EXACT PSI-MOD-alternate []
synonym	"N-butyrylation" EXACT PSI-MOD-alternate []
synonym	"NButRes" EXACT PSI-MOD-label []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 N 0 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "none"
xref	TermSpec: "none"
is_a	MOD:01996 butanoylated residue ! butanoylated residue

2.1998. MOD:01998 alpha-amino butanoylated residue

Table 2000. Term [MOD:01998]
id	MOD:01998
name	alpha-amino butanoylated residue
def	"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a butanoyl group." [PubMed:18688235]
synonym	"N2ButRes" EXACT PSI-MOD-label []
xref	DiffAvg: "70.09"
xref	DiffFormula: "C 4 H 6 N 0 O 1"
xref	DiffMono: "70.041865"
xref	Formula: "none"
xref	MassAvg: "none"
xref	MassMono: "none"
xref	Origin: "X"
xref	Source: "artifact"
xref	TermSpec: "N-term"
is_a	MOD:01997 N-butanoylated residue ! N-butanoylated residue

2.1999. MOD:01999 N6-(11-cis)-retinylidene-L-lysine

Table 2001. Term [MOD:01999]
id	MOD:01999
name	N6-(11-cis)-retinylidene-L-lysine
def	"A protein modification that effectively converts an L-lysine residue to N6-retinylidene-(11-cis)-L-lysine." [PubMed:18688235]
synonym	"(2S)-2-amino-6-[(2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)-2,4,6,8-nonatetraenylidene]aminohexanoic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "266.43"
xref	DiffFormula: "C 20 H 26 N 0 O 0"
xref	DiffMono: "266.203451"
xref	Formula: "C 26 H 38 N 2 O 1"
xref	MassAvg: "394.60"
xref	MassMono: "394.298414"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:02000 N6-retinylidene-L-lysine (unspecified geometric isomer) ! N6-retinylidene-L-lysine (unspecified geometric isomer)

2.2000. MOD:02000 N6-retinylidene-L-lysine (unspecified geometric isomer)

Table 2002. Term [MOD:02000]
id	MOD:02000
name	N6-retinylidene-L-lysine (unspecified geometric isomer)
def	"A protein modification that effectively converts an L-lysine residue to N6-retinylidene-L-lysine (unspecified geometric isomer)." [PubMed:18688235]
synonym	"(2S)-2-amino-6-[3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)-2,4,6,8-nonatetraenylidene]aminohexanoic acid" EXACT PSI-MOD-alternate []
xref	DiffAvg: "266.43"
xref	DiffFormula: "C 20 H 26 N 0 O 0"
xref	DiffMono: "266.203451"
xref	Formula: "C 26 H 38 N 2 O 1"
xref	MassAvg: "394.60"
xref	MassMono: "394.298414"
xref	Origin: "K"
xref	Source: "natural"
xref	TermSpec: "none"
is_a	MOD:00912 modified L-lysine residue ! modified L-lysine residue

2.2001. contains contains

Table 2003. Typedef [contains]
id	contains
name	contains
def	"'Entity A' contains 'Entity B' implies that 'Entity B' is a part of the structure of 'Entity A'." [PubMed:18688235]
comment	The inverse relationship to "part of".
is_transitive	true

2.2002. derives_from derives from

Table 2004. Typedef [derives_from]
id	derives_from
name	derives from
def	"'Entity A' derives_from 'Entity B' implies that 'Entity A' is chemically derived from 'Entity B'." [PubMed:18688235]
is_transitive	true

2.2003. has_functional_parent has functional parent

Table 2005. Typedef [has_functional_parent]
id	has_functional_parent
name	has functional parent
def	"'Entity A' has_functional_parent 'Entity B' implies that 'Entity B' has at least one chacteristic group from which 'Entity A' can be derived by functional modification." [PubMed:18688235]
comment	This relationship indicates that the formula and mass of the child are not inherited from the mass of the parent.
is_transitive	true

2.2004. part_of part of

Table 2006. Typedef [part_of]
id	part_of
name	part of
def	"'Entity A' part_of 'Entity B' implies that 'Entity A' is a part of the structure of 'Entity B'." [PubMed:18688235]
is_transitive	true

PSI-MOD Ontology

1. Document Metadata

2. Definitions and Terms

2.1. MOD:00001 alkylated residue

2.2. MOD:00002 O-glycosyl-L-serine

2.3. MOD:00003 UniMod

2.4. MOD:00004 artifact

2.5. MOD:00005 O-glycosyl-L-threonine

2.6. MOD:00006 N-glycosylated residue

2.7. MOD:00007 selenium substitution for sulfur

2.8. MOD:00008 common

2.9. MOD:00009 natural residue

2.10. MOD:00010 L-alanine residue

2.11. MOD:00011 L-arginine residue

2.12. MOD:00012 L-asparagine residue

2.13. MOD:00013 L-aspartic acid residue

2.14. MOD:00014 L-cysteine residue

2.15. MOD:00015 L-glutamic acid residue

2.16. MOD:00016 L-glutamine residue

2.17. MOD:00017 glycine residue

2.18. MOD:00018 L-histidine residue

2.19. MOD:00019 L-isoleucine residue

2.20. MOD:00020 L-leucine residue

2.21. MOD:00021 L-lysine residue

2.22. MOD:00022 L-methionine residue

2.23. MOD:00023 L-phenylalanine residue

2.24. MOD:00024 L-proline residue

2.25. MOD:00025 L-serine residue

2.26. MOD:00026 L-threonine residue

2.27. MOD:00027 L-tryptophan residue

2.28. MOD:00028 L-tyrosine residue

2.29. MOD:00029 L-valine residue

2.30. MOD:00030 N-formyl-L-methionine residue

2.31. MOD:00031 L-selenocysteine residue

2.32. MOD:00032 uncategorized protein modification

2.33. MOD:00033 crosslinked residues

2.34. MOD:00034 L-cystine (cross-link)

2.35. MOD:00035 (2S,3R)-3-hydroxyasparagine

2.36. MOD:00036 (2S,3R)-3-hydroxyaspartic acid

2.37. MOD:00037 5-hydroxy-L-lysine

2.38. MOD:00038 3-hydroxy-L-proline

2.39. MOD:00039 4-hydroxy-L-proline

2.40. MOD:00040 2-pyrrolidone-5-carboxylic acid (Gln)

2.41. MOD:00041 L-gamma-carboxyglutamic acid

2.42. MOD:00042 L-aspartic 4-phosphoric anhydride

2.43. MOD:00043 S-phospho-L-cysteine

2.44. MOD:00044 1'-phospho-L-histidine

2.45. MOD:00045 3'-phospho-L-histidine

2.46. MOD:00046 O-phospho-L-serine

2.47. MOD:00047 O-phospho-L-threonine

2.48. MOD:00048 O4'-phospho-L-tyrosine

2.49. MOD:00049 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine

2.50. MOD:00050 N-acetyl-L-alanine

2.51. MOD:00051 N-acetyl-L-aspartic acid

2.52. MOD:00052 N-acetyl-L-cysteine

2.53. MOD:00053 N-acetyl-L-glutamic acid

2.54. MOD:00054 N-acetyl-L-glutamine

2.55. MOD:00055 N-acetylglycine

2.56. MOD:00056 N-acetyl-L-isoleucine

2.57. MOD:00057 N2-acetyl-L-lysine

2.58. MOD:00058 N-acetyl-L-methionine

2.59. MOD:00059 N-acetyl-L-proline

2.60. MOD:00060 N-acetyl-L-serine

2.61. MOD:00061 N-acetyl-L-threonine

2.62. MOD:00062 N-acetyl-L-tyrosine

2.63. MOD:00063 N-acetyl-L-valine

2.64. MOD:00064 N6-acetyl-L-lysine

2.65. MOD:00065 S-acetyl-L-cysteine

2.66. MOD:00066 N-formylglycine

2.67. MOD:00067 N-D-glucuronoylglycine

2.68. MOD:00068 N-myristoylglycine

2.69. MOD:00069 N-palmitoyl-L-cysteine

2.70. MOD:00070 N-methyl-L-alanine

2.71. MOD:00071 N,N,N-trimethyl-L-alanine

2.72. MOD:00072 N-methylglycine

2.73. MOD:00073 N-methyl-L-methionine

2.74. MOD:00074 N-methyl-L-phenylalanine

2.75. MOD:00075 N,N-dimethyl-L-proline

2.76. MOD:00076 symmetric dimethyl-L-arginine

2.77. MOD:00077 asymmetric dimethyl-L-arginine